ライフサイエンスコーパス: hairy

1 ophila in that it includes Tc-odd but not Tc-hairy.

2 In contrast, long-range repressors such as Hairy act over distances >1 kb.

3 Fibrillar, or "hairy," adhesives have evolved multiple times independen

4 ved Hairy/Enhancer of Split family repressor Hairy, analyzing histone marks and gene expression in Dr

5 es that differentiate this species from its 'hairy' ancestors.

6 We show that Hairy and Dl function concertedly and nonredundantly to

7 o a prepattern of repression, established by Hairy and Dl, which unfolds progressively during larval

8 h signaling and induced the transcription of hairy and E (spl)-1 (HES)-1, by Notch-independent mechan

9 evels of cyclin A2, cyclin B1, cyclin E2 and hairy and enhancer of split (Hes) 1.

10 , a pro-neuronal differentiation factor, and Hairy and Enhancer of Split (HES1), a transcription repr

11 Hairy and enhancer of split 1 (Hes-1) is a mammalian tra

12 t Notch1, but not Notch2, activation induced hairy and enhancer of split 1 (HES1) expression and gene

13 by NOTCH receptors, which signal through the Hairy and Enhancer of Split 1 (HES1) transcription regul

14 EBNA2 and EBNALP, EBNALP was associated with hairy and enhancer of split 1 (hes1), cd21, cd23, and ar

15 helix-loop-helix (bHLH) transcription factor hairy and enhancer of split 1 (HES1).

16 and autoimmune diseases, activate the Notch1-hairy and enhancer of split 1 (Notch1-HES1) axis in targ

17 n of the biliary stem-cell signaling pathway hairy and enhancer of split 1/pancreatic duodenal homeob

18 the expression of the specific target genes hairy and enhancer of split 3 (Hes3) and Sonic hedgehog

19 MEM106B, PDIA6 and the Notch signaling genes hairy and enhancer of split 4 (HES4) and JAGGED2, suppor

20 TAp63 transactivates hairy and enhancer of split 5 (Hes5) and atonal homolog

21 The initial efforts identify that hairy and enhancer of split 6 (Hes6), a novel transcript

22 ty shift assays, we show that Pax3 regulates Hairy and enhancer of split homolog-1 (Hes1) and Neuroge

23 Two gene families, HES (hairy and Enhancer of Split) and KIF1 (kinesin-like prot

24 HES1 (hairy and enhancer of split) is a transcription factor t

25 ression, as well as downstream targets HES1 (hairy and enhancer of split-1) and CCND1 (cyclin D1).

26 F-kappaB but also results in decreased Hes1 (hairy and enhancer of split-1), a negative regulator of

27 re accompanied by a reduction in Notch-1 and Hairy and enhancer of split-5 (Hes-5) mRNA and protein l

28 k from NOTCH3 receptor signaling through the Hairy and enhancer of Split-5 (HES-5) protein to smooth

29 Notch induces Hairy and Enhancer of Split-related with YRPW motif (Hey

30 signaling pathway: the transcription factor, hairy and enhancer of Split1 (HES1) and two members of t

31 The afferent inputs from hairy and glabrous skin are distinct with respect to bot

32 Laser stimulation of hairy and glabrous skin at the same energy elicited rema

33 im of this study was to assess the effect of hairy and glabrous skin stimulation on neural transmissi

34 reshold mechanoreceptors that innervate both hairy and glabrous skin.

35 using the prototypical long-range repressor Hairy and the short-range repressor Knirps.

36 interacts synergistically with the repressor hairy and with Dpp signaling in posterior and anterior r

37 Strikingly, five TFs (nf-kb, egr, pax6, hairy, and clockwork orange) were predicted to co-regula

38 trate that the products of the genes stripe, hairy, and extramacrochaetae contribute to rescue by ant

39 le genes even-skipped, odd-skipped, runt and hairy are all expressed as early blastoderm pair-rule st

40 Hairy attachment structures (fossula spongiosa), present

41 Transcriptome analysis of hairy B. villosa leaves indicated higher expression of s

42 r, transcripts of the TRY inhibitory gene in hairy B. villosa were surprisingly high relative to B. n

43 The gain of eccrine sweat glands in hairy body skin has empowered humans to run marathons an

44 e expression differences in an exceptionally hairy Brassica species compared with a glabrous species

45 y, which disrupts the repressive activity of Hairy by inhibiting the recruitment of its cofactor Grou

46 eukaemia is reviewed, focussing first on the hairy cell itself and then on its interactions with the

47 arge fraction of melanomas, thyroid cancers, hairy cell leukaemias and, to a smaller extent, a wide s

48 ia (29), T-cell prolymphocytic leukemia (3), hairy cell leukemia (1), adult T-cell leukemia/lymphoma

49 V600E mutation was reported in all cases of hairy cell leukemia (HCL) but not in other peripheral B-

50 BRAFV600E mutation was recently detected in hairy cell leukemia (HCL) by whole exome sequencing.

51 tic leukemia (CLL) cases, 100% (32 of 32) of hairy cell leukemia (HCL) cases, 15% (5 of 34) of mantle

52 Hairy cell leukemia (HCL) is a chronic B-cell leukemia n

53 Hairy cell leukemia (HCL) is a chronic mature B-cell neo

54 Hairy cell leukemia (HCL) is a distinct clinicopathologi

55 Hairy cell leukemia (HCL) is a distinct clinicopathologi

56 Hairy cell leukemia (HCL) is a rare, indolent B-cell dis

57 Hairy cell leukemia (HCL) is characterized by underexpre

58 Hairy cell leukemia (HCL) is marked by near 100% mutatio

59 Hairy cell leukemia (HCL) shows unique clinicopathologic

60 iral oncogene homolog B1 (BRAF) mutations in hairy cell leukemia (HCL) subsets, demonstrating that BR

61 To compare hairy cell leukemia (HCL) with chronic lymphocytic leuke

62 produce high response rates in patients with hairy cell leukemia (HCL), a significant number of patie

63 ), 7 of 7 follicular lymphoma (FL), 13 of 17 hairy cell leukemia (HCL), and 2 of 3 mantle cell lympho

64 target on B-cell malignancies, particularly hairy cell leukemia (HCL), but its soluble extracellular

65 e (BRAF V600E) is the key driver mutation in hairy cell leukemia (HCL), suggesting opportunities for

66 defining the BRAF-V600E driving mutation in hairy cell leukemia (HCL),provide extensive laboratory s

67 nd also occurs in the hematopoietic neoplasm hairy cell leukemia (HCL).

68 recently described as a molecular marker of hairy cell leukemia (HCL).

69 duces protracted remissions in patients with hairy cell leukemia (HCL).

70 accepted as the agent of choice in treating hairy cell leukemia (HCL).

71 ious CDKN1B mutation in 16% of patients with hairy cell leukemia (HCL).

72 ates when used as first-line monotherapy for hairy cell leukemia (HCL); however, patients continue to

73 low-grade follicular lymphoma (FL; n = 44), hairy cell leukemia (HCL; n = 15), and reactive lymphoid

74 cally, this paper describes the frequency of hairy cell leukemia among all adult leukemias and charac

75 ons is helpful in the diagnosis of classical hairy cell leukemia and a number of histiocytic neoplasm

76 Immunotoxin therapy is very effective in hairy cell leukemia and also has activity in other hemol

77 lymphoid neoplasm subtypes, most notably for hairy cell leukemia and follicular lymphoma, black predo

78 ate of complete remissions in drug-resistant hairy cell leukemia and has a lower response rate in ped

79 RITs have shown efficacy in refractory hairy cell leukemia and in some children with acute lymp

80 with reports of only a few cases of variant hairy cell leukemia and neurological disease associated

81 ladribine is best known for the treatment of hairy cell leukemia and other lymphoid cancers, it also

82 The description of hairy cell leukemia as a specific clinical entity was pu

83 HA22 is very active in drug-resistant hairy cell leukemia but is less active in children with

84 V600E-expressing human primary melanoma and hairy cell leukemia cells.

85 The Hairy Cell Leukemia Foundation convened an international

86 ibine followed by rituximab in patients with hairy cell leukemia including the vari-ant form (HCLv).

87 Hairy cell leukemia is an uncommon hematologic malignanc

88 Enormous progress in the treatment of hairy cell leukemia over the last five decades has emerg

89 Immunophenotypic features in classic hairy cell leukemia show that the leukemic cells express

90 utcome of young patients with a diagnosis of hairy cell leukemia treated with cladribine.

91 Hairy cell leukemia variant (HCLv) presents with high di

92 notoxin treatment and report that samples of hairy cell leukemia with high levels of Bim protein resp

93 ity against chronic lymphocytic leukemia and hairy cell leukemia, in general, monoclonal antibodies h

94 al blood samples obtained from patients with hairy cell leukemia, marginal zone lymphoma, and chronic

95 lymphoma, CLL, acute lymphoblastic leukemia, hairy cell leukemia, non-Hodgkin lymphoma (including rit

96 d many complete remissions in drug-resistant Hairy cell leukemia, where many treatment cycles can be

97 ts profound impact on the natural history of hairy cell leukemia, with responses approaching 100% and

98 1 in both leukemia and lymphoma, and BRAF in hairy cell leukemia.

99 ll known and revolutionized the treatment of hairy cell leukemia.

100 signaling important for the pathogenesis of hairy cell leukemia.

101 ted kinase (ERK) in the hairy cells (HCs) of hairy cell leukemia.

102 time the clinical and pathologic features of hairy cell leukemia.

103 The biology of hairy-cell leukaemia is reviewed, focussing first on the

104 BRAF inhibitor vemurafenib in patients with hairy-cell leukemia that had relapsed after treatment wi

105 d many complete remissions in drug-resistant hairy-cell leukemia when several cycles of the agent can

106 B-Raf kinase (BRAF mutations) are present in hairy-cell leukemia, cutaneous melanoma, thyroid carcino

107 BRAF V600E is the genetic lesion underlying hairy-cell leukemia.

108 tive in patients with relapsed or refractory hairy-cell leukemia.

109 isms driving variant and IGHV4-34-expressing hairy-cell leukemias, we performed whole-exome sequencin

110 Hairy cells (HCs) are mature malignant B cells that cont

111 ellular signal-regulated kinase (ERK) in the hairy cells (HCs) of hairy cell leukemia.

112 Hairy cells are highly activated clonal B cells related

113 ete response (CR), defined as presence of no hairy cells in BM and blood with normalization of counts

114 r signal-regulated kinase phosphorylation of hairy cells in vivo.

115 The activation of hairy cells makes them unusually sensitive to interferon

116 third-party observers, in the context of the Hairy-Downy game.

117 s signal primarily through the regulation of hairy enhancer of split (HES) and HES-related (HRT) gene

118 transcription of Notch target genes, such as Hairy Enhancer of Split (Hes) and Hes-related with YRPF

119 Expression of NOTCH and hairy enhancer of split (HES) proteins was assessed in p

120 sette subfamily G member 2 (ABCG2), p63, and hairy enhancer of split 1 (Hes1) were chosen as corneoli

121 cient mice showed reduced gene expression of hairy enhancer of split 1, an intestinal progenitor cell

122 he promoter that regulates the expression of Hairy Enhancer of Split 5, an inhibitor of neurite forma

123 retase activity, Notch1 cleavage, and Hes-1 (hairy enhancer of split homolog-1) expression, all of wh

124 Hairy enhancer of split-1 was a Notch1-downstream gene e

125 transcription of Notch target genes, such as hairy enhancer of split-related with YRPW motif (Hey)1 a

126 d lack the distinguishing characteristics of Hairy/Enhancer of Split (HES) bHLH proteins that are Not

127 rgence-with a high-affinity binding site for Hairy/Enhancer of split (Hes) repressor proteins.

128 Ectopic expression of Hairy/Enhancer of Split 1 (HES1) consistently reproduced

129 tors (Notch1-4), or through the Notch target Hairy/Enhancer of Split 1 (HES1), consistently leads to

130 Notch effector, and represses Notch-induced Hairy/Enhancer of Split 1 activity.

131 Therefore, we studied the conserved Hairy/Enhancer of Split family repressor Hairy, analyzin

132 of Hes (Hairy/Enhancer of Split)-1 and Hey (Hairy/Enhancer of Split related with YRPW)1 (primary tar

133 Expression of the hairy/enhancer of split transcription factor hes6, is al

134 ase reporter assays and localization of Hes (Hairy/Enhancer of Split)-1 and Hey (Hairy/Enhancer of Sp

135 Retroviral expression of Hairy/Enhancer of Split-1 (Hes1) recapitulated the Notch

136 Hairy/Enhancer of Split-1, which is expressed in Clara c

137 The expression of hairy/Enhancer of split-related 1 (her1) is affected fir

138 a reduction in endodermal expression of the hairy/enhancer of split-related gene, her5, at mid to la

139 s deltaC and deltaD, and finally, by another hairy/Enhancer of split-related gene, her7.

140 ing analysis and identified that Hey1 of the hairy/Enhancer of split-related repressor protein basic

141 The Notch target Hairy/Enhancer of Split1 (HES1) is sufficient to reprodu

142 ivity or deleting the downstream target gene Hairy/Enhancer-of-split 1, results in an increase in Ley

143 ch-regulated targets, including genes of the hairy/enhancer-of-split family in organisms ranging from

144 lences Notch, Neuralized and all three Ciona Hairy/Enhancer-of-Split genes.

145 g to enhanced expression of the Notch target hairy/enhancer-of-split related with YRPW motif protein

146 Here, we reveal that Hey2, a hairy/enhancer-of-split-related basic helix-loop-helix t

147 Most strikingly, Hairy exhibits biochemical activity on many loci that ar

148 We also explore the regulation of periodic hairy expression.

149 , using numerical simulations, we show that "hairy" (f-star) or DNA grafted on nanocubes provides a g

150 Female hairy-faced hover wasps forage for the young of a domina

151 Binding sites for the transcription factors Hairy, GAGA, Adf1, Cf1, Snail, and Dri, known to functio

152 was not effective in induction of Kr-h1 and Hairy gene expression in vitro in fat bodies of female m

153 directs spatially dynamic expression of the Hairy gene her5.

154 imer mediates JH III activation of Kr-h1 and Hairy genes in the context of light-dependent circadian

155 nt Physalis pubescens L., commonly named as "hairy groundcherry" in English and "Deng-Long-Cao" in Ch

156 Three genes, extramacrochaetae (emc), hairy (h) and stripe (sr), involved in repression have b

157 ese roles are distinct from the bHLH protein Hairy (H), which we show restricts atonal (ato) expressi

158 tous digital dermatitis (PDD), also known as hairy heel wart, is a growing cause of lameness of cows

159 uences, including a C-terminal WRPW/Y motif (Hairy/Hes/Runx) and internal eh1 motifs (FxIxxIL; Engrai

160 ant resulted in inflammation and swelling of hairy hind foot skin in rats, a transient thermal hypera

161 as found to be significantly enhanced in the hairy hindpaw skin and its receptor GDNF family receptor

162 Western blot and real-time PCR analysis of hairy hindpaw skin and L2/L3 DRGs after saphenous nerve

163 Real-time PCR analysis of L2/L3 DRGs and hairy hindpaw skin at various times after saphenous nerv

164 In contrast, Hairy induces widespread histone deacetylation and inhib

165 sized pollen grains that can easily stick to hairy insects for pollination to nanoscale virus particl

166 Epstein-Barr virus (EBV) causes hairy leukoplakia (HL), a benign lesion of oral epitheli

167 F-7 protein expression in vivo in lesions of hairy leukoplakia (HLP) in which there is abundant EBV r

168 as nasopharyngeal carcinoma (NPC), and oral hairy leukoplakia (OHL) lesions that have lytic infectio

169 ription from Zp, with all Z(+) cells in oral hairy leukoplakia being BLIMP1(+).

170 ses are due to lytic infection (such as oral hairy leukoplakia) or latent infection (such as nasophar

171 Here we demonstrate that the Arabidopsis HAIRY MERISTEM (HAM) family of transcription regulators

172 The Petunia hybrida HAIRY MERISTEM (HAM) gene, a member of the GRAS family o

173 including its specific expression signature, hairy morphology, and antiapoptotic behavior.

174 Hairy nanoparticles are employed as multifunctional node

175 r PAA, demonstrating the capability of these hairy nanoparticles to undergo chain reorganization in r

176 ng the BclA protein that contributes to the 'hairy nap' layer.

177 BclA and related proteins form the hairy nap, and require ExsFA (BxpB) for their localizati

178 a 2D-crystalline basal layer, overlaid by a hairy nap.

179 degrees C showed that addition of 1 wt % of hairy NPs into PAO led to significant reductions in coef

180 These hairy NPs represent a new type of lubricating oil additi

181 These hairy NPs showed exceptional stability in poly(alphaolef

182 The excellent lubricating properties of hairy NPs were further elucidated by the characterizatio

183 lymer brush-grafted inorganic nanoparticles (hairy NPs) as highly effective lubricant additives for f

184 mulated with retinoic acid and rat split and hairy related proteins constitute a structurally distinc

185 analyses revealed that endogenous levels of Hairy Related Transcription (HRT) factor 2 (HRT2) peaked

186 Here, we establish Gridlock (Grl), a Hairy-related basic helix-loop-helix (bHLH) transcriptio

187 We previously reported that mice lacking the hairy-related basic helix-loop-helix (bHLH) transcriptio

188 The hairy-related family of transcriptional repressors (Hrt)

189 sion of the transcriptional repressors HRT1 (Hairy-related transcription factor 1) and HRT2, in a CBF

190 c helix-loop-helix transcriptional repressor Hairy-related transcription factor 2 (Hrt2) is expressed

191 Hairy-related transcription factor proteins, which antag

192 the expression of Notch downstream effectors hairy-related transcription factors.

193 ations in Notch2, Jagged1 or homologs of the Hairy-related transcriptional repressor Hey2 cause conge

194 atin immunoprecipitation, we have analyzed a Hairy-repressible gene in the embryo during activation a

195 In these assays, the Hairy repression domain did not exhibit previously descr

196 s silenced using RNA interference in soybean hairy root composite plants, these plants had severely r

197 terference of isoflavone synthase in soybean hairy root composite plants.

198 Overexpression of MYB182 in hairy root culture and whole poplar plants led to reduce

199 yptamine biosynthesis in Catharanthus roseus hairy root culture eliminates all production of monoterp

200 , and increased nicotine accumulation in the hairy root culture media.

201 Peanut (Arachis hypogaea) hairy root cultures produce a diverse array of prenylate

202 transferase genes in elicitor-treated peanut hairy root cultures.

203 lium under N-limited growth conditions using hairy root cultures.

204 have been targeted at either whole plants or hairy root cultures.

205 related pathogens that cause crown gall and hairy root diseases, which result from integration and e

206 tants, yucca6 plants do not display short or hairy root phenotypes and lack morphological changes und

207 However, hairy root transformation had notable influence on Sphin

208 The effect of hairy root transformation on rhizosphere bacterial commu

209 hat cause different diseases, crown gall and hairy root.

210 A hairy-root transformation system was employed to investi

211 ling of mttt8 mutant seeds and M. truncatula hairy roots (mttt8 mutant, mttt8 mutant complemented wit

212 Compared with control roots, CrWRKY1 hairy roots accumulated up to 3-fold higher levels of se

213 Overexpression of MtMATE69 in hairy roots altered Fe homeostasis and hormone levels un

214 and their conjugates in Medicago truncatula hairy roots and anthocyanin-overproducing tobacco (Nicot

215 ocyanin and PA accumulation in M. truncatula hairy roots and Arabidopsis thaliana seeds, respectively

216 ores anthocyanins and PAs in mttt8 plant and hairy roots and further enhances both productions in wil

217 Transcriptome analyses of overexpressing hairy roots and knockout mutants of MtMYB5 and MtMYB14 i

218 owever, when complex expression systems like hairy roots are used for production, multiple population

219 Histochemical staining of transgenic hairy roots carrying the promoter-reporter constructs in

220 entified as a key player in the formation of hairy roots during the plant-A. rhizogenes interaction.

221 Medicago truncatula hairy roots expressing LaPT1 accumulated isowighteone, a

222 NUP1-RNAi hairy roots had reduced NUP1 mRNA accumulation levels, r

223 SPARENT TESTA 2 (TT2) in Medicago trunculata hairy roots induces both proanthocyanidin accumulation a

224 decreased the number of galls in transformed hairy roots inoculated with RKN.

225 Overexpression of MtMATE66 rendered hairy roots more tolerant to Al(3+) toxicity.

226 e accumulation of proanthocyanidins (PAs) in hairy roots of Medicago truncatula.

227 PAR was expressed ectopically in transformed hairy roots of Medicago.

228 xpression of TSAR1 or TSAR2 in M. truncatula hairy roots resulted in elevated transcript levels of kn

229 the ectopic expression of MYB15 in grapevine hairy roots resulted in increased STS expression and in

230 The overexpression of CrWRKY1 in C. roseus hairy roots up-regulated several key TIA pathway genes,

231 Overexpression of CrMAPKK1 in C. roseus hairy roots upregulated TIA pathways genes and increased

232 gly induces PA accumulation in M. truncatula hairy roots, and both myb5 and myb14 mutants of M. trunc

233 analysis of par mutants and MtPAR-expressing hairy roots, coupled with yeast one-hybrid analysis, rev

234 C2-L3 was ectopically expressed in grapevine hairy roots, showing a reduction in proanthocyanidin con

235 Using composite plants with transgenic hairy roots, we show that RDN1 and RDN2 orthologs from d

236 s of phytoplasma-infected plants, by forming hairy roots.

237 to 4-methyl tryptophan inhibition of CrWRKY1 hairy roots.

238 antly while chrysin glycosides accumulate in hairy roots.

239 ic increase of TIA accumulation in C. roseus hairy roots.

240 ivity from the microsomal fraction of peanut hairy roots.

241 rther enhances both productions in wild-type hairy roots.

242 hpRNA mediated gene silencing in transgenic, hairy roots.

243 or tanshinone production in elicited Danshen hairy roots.

244 ce when over-expressed in transgenic soybean hairy roots.

245 factor was observed in MYB182-overexpressing hairy roots.

246 Drosophila pair-rule genes even-skipped and hairy, show periodic expression in the posterior disc, c

247 the three major hair follicle types of trunk hairy skin (guard, awl/auchene, and zigzag hairs) is inn

248 their relative patterns of axonal endings in hairy skin and the spinal cord.

249 Light mechanical stimulation of hairy skin can induce a form of itch known as mechanical

250 The piloneural collar in mammalian hairy skin comprises an intricate pattern of circumferen

251 echanoafferents (C tactile, CT) in the human hairy skin have recently been linked to pleasant touch s

252 rst pain to heat stimulation of glabrous and hairy skin in humans.

253 ory neurons that detect pleasant stroking of hairy skin in vivo have not been reported.

254 s always had significantly longer latencies (hairy skin N2 wave, +75%; P2 wave, +56%) and smaller amp

255 +75%; P2 wave, +56%) and smaller amplitudes (hairy skin N2 wave, -42%; P2 wave, -19%) than LEPs.

256 t of tactile stimulation differs between the hairy skin of the arm, and the glabrous skin of the palm

257 examined neuron had a receptive field on the hairy skin of the hindlimb and responded to noxious mech

258 y of cutaneous sensory arbor morphologies in hairy skin of the mouse using genetically-directed spars

259 from these cells provide innervation to the hairy skin of the perineal region and can be activated b

260 On the hairy skin of the upper limb, spatial acuity for pain an

261 mechanosensitive C fibers that innervate the hairy skin represent the neurobiological substrate for t

262 ratings similar to those obtained following hairy skin stimulation, and CHEPs following glabrous ski

263 e, -40%; P2 wave, -44%) than CHEPs following hairy skin stimulation.

264 These neurons exclusively innervate hairy skin with large terminal arborizations that resemb

265 the upper lip (glabrous skin) and the chin (hairy skin).

266 ns are activated by massage-like stroking of hairy skin, but not by noxious punctate mechanical stimu

267 pheral nociceptor sensitization in hind foot hairy skin, but not glabrous skin, rapidly activates a d

268 When heat stimuli are applied to primate hairy skin, first pain sensation is mediated by type-II

269 In mouse hairy skin, lanceolate complexes associated with three t

270 In mouse hairy skin, Mrgprd, as marked by expression of green flu

271 In the glabrous and hairy skin, rare Merkel endings and transverse lanceolat

272 rogenitors that reside in the touch domes of hairy skin, termed touch dome progenitor cells (TDPCs).

273 In hairy skin, transient hyperalgesia was associated with s

274 afferent classes that innervate glabrous and hairy skin.

275 expressing neurons innervate exclusively the hairy skin.

276 ic sensory fibers that exclusively innervate hairy skin.

277 ic types of gentle mechanical stimulation on hairy skin.

278 c diblock DNA copolymers self-assemble into "hairy", star-like micelles, shown in the AFM image and t

279 tudies, we have found that expression of two hairy stripes along the D/V axis is induced in response

280 Here, we show that expression of two other hairy stripes along the orthogonal A/P axis is establish

281 nd cyclin D1, smoothening of leukemic cells' hairy surface, and, eventually, apoptosis.

282 Nature relies on 'hairy' surfaces to protect blood capillaries from wear a

283 enhancers and long-range repressors such as Hairy that can dominantly inhibit distal elements.

284 ctors, many regions are targeted errantly by Hairy to modify the chromatin landscape.

285 rofile signature, change of morphology from "hairy" to "smooth," and eventually apoptosis.

286 ave been attributed to specialized feet with hairy toes that uncurl and peel in milliseconds.

287 found that three direct targets of ECR/USP--hairy, vrille, and Hr4--are required for cellular differ

288 ession of two JH-responsive genes, Kr-h1 and Hairy, was dependent on both the ratio of light to dark

289 itates the ubiquitylation of the HES protein Hairy, which disrupts the repressive activity of Hairy b

290 artially established by the prepattern gene, hairy, which represses ac expression in four of eight in

291 ila insulator proteins such as Suppressor of Hairy wing [SU(HW)] and Boundary Element Associated Fact

292 The Drosophila Suppressor of Hairy wing [Su(Hw)] insulator protein has an essential r

293 Suppressor of Hairy-wing [Su(Hw)] is a DNA-binding factor required for

294 The Drosophila Suppressor of Hairy-wing [Su(Hw)] protein is a globally expressed, mul

295 trovirus binds the zinc-finger Suppressor of Hairy-wing [Su(Hw)] protein that associates with hundred

296 genomic-binding sites for the Suppressor of Hairy-wing [Su(Hw)] protein, a component of the gypsy in

297 generate binding sites for the Suppressor of Hairy-wing [Su(Hw)] protein.

298 gulation, we studiedDrosophila Suppressor of Hairy-wing [Su(Hw)], an exemplar multifunctional polydac

299 specific transcription factor (Suppressor of Hairy-wing) and a histone modification (H3K36me3).

300 luding compact body conformations, extremely hairy winter coats, and acute seasonal differences in me