ライフサイエンスコーパス: handful

1 that comprise the gD-HveA interface, only a handful are critical for complex formation.

2 dels, previous research suggests that only a handful are evolutionarily stable against invasion by fr

3 tes range from 15 to 20 channels, and only a handful are functionally understood.

4 (NBs) in bacteria of which, to-date, only a handful are known.

5 the specific biological functions of only a handful are understood at present.

6 fore, regular consumption (approximately one handful daily) of nuts over the long term, as a replacem

7 ousands of potential target peptides, only a handful generate measurable responses.

8 ctions of Holocene climate in Europe, only a handful has addressed winter conditions, and most of the

9 ation that out of thousands of seeds, only a handful have any chance of being optimal.

10 oduct antibiotics discovered to date, only a handful have been developed for the treatment of bacteri

11 le copy-number gain or loss, of which only a handful have been linked to a specific gene.

12 hundred grains and boundaries, where only a handful have been previously reported.

13 encode roughly 70 F-box proteins, but only a handful have established functions.

14 A handful, however, strike many months after birth, follow

15 It is one of a handful molecules that can expose new recognition sites

16 vidence of pervasive cotargeting, in which a handful of "hub" microRNAs are involved in a majority of

17 cells per ganglion to some containing only a handful of 5-HT(1crust)ir cells in the entire nerve cord

18 ndidate gene-based studies have identified a handful of aberrant CpG DNA methylation events in prosta

19 Only a handful of academic centers of surgical innovation exist

20 of brain function, with fMRI showing only a handful of activated regions in response to task/stimula

21 hundreds of pre-clinical candidates, only a handful of adjuvants are approved for prophylactic vacci

22 Only a handful of adjuvants have both sufficient potency and ac

23 networks are almost entirely aligned with a handful of aligners that we unify into a new tool, Ulign

24 c event, as nonhuman primates possess only a handful of AluYb elements.

25 tions in neuroscience best studied in only a handful of animal models?

26 A handful of animals, notably the fungus-growing ants, ter

27 steries remain about its key protagonists, a handful of Anopheles species.

28 Overall, only a handful of articles addressed treatment of depression wi

29 Clusters containing only a handful of atoms have been the subject of extensive theo

30 striking is the direct juxtaposition of the handful of bacterial model organisms to the 1000 prokary

31 s that contribute to biofilm formation for a handful of bacterial species.

32 Despite its evolutionary importance, only a handful of bacterial, genome-wide cytosine studies have

33 Px data for one or more TF(s) in more than a handful of biological contexts.

34 Since 2003, a handful of biological systems have been identified to di

35 Only a handful of bird species are known to use foraging tools

36 Only a handful of broadly applicable reporters have been identi

37 To date, though, only a handful of broadly useful transformations have been iden

38 Examples include metabolism where a handful of building blocks mediate between multiple inpu

39 is and degradation in enterobacteria, only a handful of c-di-GMP receptors/effectors have been identi

40 It is among a handful of cancers whose dimensions are reported in mill

41 zeolite structures led to the discovery of a handful of candidates that have sufficient methane sorpt

42 calcinosis has rarely been made, with only a handful of cases described in literature.

43 actitioner as no center will see more than a handful of cases each year.

44 e increasing acceptance of this view, only a handful of cases of adaptive gene expression evolution h

45 Recent work has highlighted a handful of cases where mobile element insertions have re

46 oups in proteins has been achieved in only a handful of cases, which typically have involved comparat

47 these changes has been elucidated in only a handful of cases.

48 gulatory antagonism previously observed in a handful of cases.

49 We also identify a handful of characteristics that drive nanoscientists' in

50 A handful of class A beta-lactamases have been discovered

51 To date, however, only a handful of ClpXP substrates have been identified.

52 oxidase, but HV 1 were known only to a tiny handful of cognoscenti around the world.

53 A handful of commercial and freely available software prog

54 ast and colorectal cancers are composed of a handful of commonly mutated gene "mountains" and a much

55 metallic neptunium chemistry, and yet only a handful of complexes have been reported, and even fewer

56 roducts were determined to consist of only a handful of compounds that quickly polymerize to form anh

57 depends on the reliability of results from a handful of computational techniques, structural alignmen

58 There are only a handful of concepts concerning cancer and carcinogenesis

59 hese hypokalemia-mediated changes occur in a handful of conditions including primary aldosteronism, d

60 We registered only a handful of conserved intronic ncRNAs of flowering plants

61 The discovery of a handful of conserved signaling pathways that dictate mos

62 nectedness, "importance") were observed in a handful of cortical regions.

63 tiffness 0.025 pN/nm) and mediated by only a handful of cross-links.

64 urvey the entire zygotic genome using just a handful of crosses.

65 ry' returns over 2500 references, yet only a handful of delivery systems have been successfully trans

66 ckground of global 5hmC loss we identified a handful of developmentally important genes that maintain

67 ion zones fail to develop fully, with only a handful of differentiated fiber cells present at birth.

68 x 6 represents an intriguing addition to the handful of diiron(IV) complexes that have been character

69 Among a handful of drug-resistant mutants, M2-S31N is the predom

70 Among the handful of drug-resistant mutants, S31N is found in more

71 for HCC is exceedingly limited, with only a handful of drugs providing benefit.

72 renorphine is available in prisons in only a handful of EECA countries (methadone or buprenorphine in

73 led to the successful characterization of a handful of effectors and it is beginning to provide insi

74 Only a handful of endogenous peptide defense signals have been

75 Only a handful of enzymes are capable of recognizing and cleavi

76 ral genomes, it has been observed for only a handful of eukaryotic genes.

77 ns is unknown, but initiator proteins from a handful of eukaryotic viruses can perform this function.

78 stigation of SMC AS has been restricted to a handful of events.

79 There are now a handful of examples of intestinal commensal bacteria wit

80 Apart from a handful of examples, however, the chemistry of these com

81 ensure this outcome is understood in only a handful of examples.

82 Only a handful of exceptional examples are known, typically inv

83 ity in data sources and study design, with a handful of exceptions, the preponderance of data indicat

84 Drawing on a small handful of exemplary studies, we review some of the majo

85 tral features have, however, been found in a handful of exotic NSs and were thought to be a manifesta

86 In contrast, there have been only a handful of experimental studies that provide data agains

87 is the best explanation for the origin of a handful of extant diploid bisexual animal taxa.

88 Only a handful of eye types exist because the physics of light

89 A handful of factors are known to function at particular d

90 A handful of families with vestibulopathy spanning several

91 d genes, and the deregulated expression of a handful of family members is associated with human tumor

92 binations such that each NK cell expresses a handful of family members.

93 ade Hampton Frost (1919-1938), was among the handful of foundational thinkers in the discipline of ep

94 A handful of free-floating planetary-mass objects have bee

95 To date, only a handful of functional sites have been identified in mamm

96 sis suggests that substantial expansion of a handful of gene families, along with extensive remodelli

97 Indeed, among a handful of general strategies for synthesizing such supr

98 monstrate that the hybrid method with only a handful of generations of the DTWF model leads to a freq

99 Only a handful of genes are known to affect the development of

100 Prior molecular efforts have focused on a handful of genes but have provided little resolution to

101 To date, only a handful of genes downstream of Math5 have been identifie

102 ies of cones and rods are well known, only a handful of genes have been identified that regulate the

103 stablished disease-causing DNA variants in a handful of genes have evolved into sequencing factories

104 nes in maize (Zea mays ssp. mays) but only a handful of genes in Arabidopsis (Arabidopsis thaliana).

105 Only a handful of genes required for the interface between pher

106 Only a handful of genes showed evidence for sequence adaptation

107 To date, only a handful of genes that control polarized localization of

108 n identified in clinical studies as one of a handful of genes whose altered expression levels or alle

109 ses in the utilization frequencies of just a handful of genes, and these genes have no clear position

110 However, a handful of genes, including the homologous genes LNK1 an

111 aberrations and the recurrent mutation of a handful of genes, such as TP53, ATM, and CCND1.

112 usceptible hosts have been limited to only a handful of genes.

113 It is known that such resistance relies on a handful of genetic lesions and/or extracellular signals

114 However, as only a handful of genetic risk factors have been investigated b

115 The review offers a handful of glimpses into these complex dynamics.

116 al cell responses can be explained by just a handful of glomeruli.

117 In contrast, only a handful of GWAS of PTSD have appeared in the literature

118 nce and memory are limited and includes only handful of hash table (BLAT, SSAHA2) or trie (Burrows-Wh

119 Metazoans use a handful of highly conserved signaling pathways to create

120 d previous studies on mRNA decay have used a handful of highly expressed transcripts as models.

121 In the protein kinase field, only a handful of highly selective allosteric modulators have b

122 However, there are only a handful of Hsp70-binding molecules known.

123 To date, however, only a handful of human-chimpanzee nucleotide differences leadi

124 Despite these striking phenotypes, only a handful of imprinted genes are known or suspected to reg

125 miting case, for the redesign of a single or handful of individual sequences.

126 ornia have diverged in allele frequency at a handful of individual SNPs, but a Kenyan sample is both

127 n 2011, extends into southern Kenya, where a handful of individuals survive in the Masai Mara.

128 By comparison, only a handful of innate visual behaviors are known in this spe

129 Recently, a handful of intergenic long noncoding RNAs (lncRNAs) have

130 ered on English as a global hub and around a handful of intermediate hub languages, which include Spa

131 merging pattern whereby class I HLA reveal a handful of internal viral ligands and whereby CTL recogn

132 ically regulated by the phosphorylation of a handful of its 49 tyrosines.

133 ical of values found in the literature for a handful of KBOs, and an "equator-on" aspect, we find 199

134 s encompass large surface areas, but often a handful of key residues dominate the binding energy land

135 y across plant ecological strategies using a handful of key traits.

136 e progress made in this area is limited to a handful of known cases of small molecules that target sp

137 There are currently only a handful of known centriole proteins.

138 sulfur response regulator, SurR, is among a handful of known redox-active transcriptional regulators

139 Although there are a handful of known riboswitches, our knowledge in this fie

140 lence or marker genes is mainly focused on a handful of known species, and shotgun metagenomics is li

141 ence of molecular linkage maps for all but a handful of laboratory and domesticated animals.

142 Only a handful of Lactobacillus species is found in caries lesi

143 that rival those previously found only at a handful of large sequencing centers.

144 was implemented by Portuguese who imported a handful of macaques from Java to Mauritius Island.

145 owever, these studies were limited to only a handful of mammalian origins, and it remains unclear how

146 fic loci led to the identification of only a handful of mammalian replication origins.

147 techniques were used to sequence the Y for a handful of mammalian species.

148 derlying mechanisms remain contentious, as a handful of markers usually provides little power to dete

149 expression data from thousands of genes to a handful of metagenes.

150 A handful of methods stand out as providing the best balan

151 ription factor, one usually has to compare a handful of methods.

152 ocytes and raise the possibility that only a handful of microRNAs may ultimately be responsible for t

153 Although some targets of a handful of miRNAs are known, the number and identities o

154 ons (NTA) are a common phenomenon, and for a handful of miRNAs the additions have been demonstrated t

155 A handful of mitochondrial ribosomal proteins appear to be

156 ge of Y chromosome sequences is limited to a handful of model organisms, constraining our understandi

157 Despite the observation of a handful of modified viral RNAs five decades ago, very li

158 s of SIRT6 in physiology and disease, only a handful of molecular and functional interactions of SIRT

159 strategies that concentrate on only one or a handful of molecular targets limits the utility of the i

160 This wide spectrum of use is based on only a handful of molecules, the majority of which belong to th

161 memory consolidation remain restricted to a handful of molecules.

162 usceptibility to Parkinson's disease, only a handful of monogenic causes of parkinsonism have been id

163 Among the handful of monophosphine ligands that effect asymmetric

164 C) by constructing and characterizing only a handful of multiple-point mutants.

165 arable stability can be effected with just a handful of mutations in a small protein.

166 , and its scope has been limited by the mere handful of natural combinations.

167 n has proven extremely difficult with only a handful of NMR-based models proposed, suggesting a need

168 peptidase, using this approach identified a handful of novel endogenous DPP4 substrates.

169 Only a handful of NSCLC patients have been included in DC clini

170 However, recent analyses have turned up a handful of nuclear genes in chromalveolates that are of

171 Water ice has been reported in a handful of objects, but most appear spectrally featurele

172 ock powerful global plant predictions from a handful of open-access field measurements.

173 ranscription, plays a primary role at only a handful of origins, but subtly influences initiation tim

174 Review of this case, as well as a handful of other cases of infantile Cushing disease in t

175 features that are only present in at most a handful of other genes.

176 sin), ZFYVE26/SPG15, SPG7 (paraplegin) and a handful of other rare genes, but many cases remain genet

177 modest, the stability of sensors employing a handful of other reporters, including anthraquinone, Nil

178 ved fossil biotas of the Burgess Shale and a handful of other similar Cambrian deposits provide rare

179 measured conformational changes, when only a handful of pairwise constraints are used (</=10).

180 n living organisms, is represented only by a handful of papers.

181 By collapsing structural diversity to a handful of parameters, such methods can be used to delin

182 mizing model hyperparameters only requires a handful of passes through the data.

183 Although originally identified in a handful of pathogenic bacteria, T3SSs are encoded by a l

184 A handful of pediatric patients undergoing sequential LT a

185 Currently only a handful of people worldwide have undergone this procedur

186 Most functional biomaterials are based on a handful of peptide sequences derived from protein ligand

187 ered biomaterials have been generated from a handful of peptides that were selected and exploited for

188 To date, only a handful of phosphoproteins with important biological fun

189 However, only a handful of pioneering studies describe the dynamics of p

190 t that these studies all fall prey to only a handful of pitfalls.

191 tissue-specific roles have been shown for a handful of plant ARF-GEFs, a fundamental yet unanswered

192 However, only a handful of plant signaling peptides have been reported.

193 only few multicellular species, limited to a handful of plants and animals, have been shown to fulfil

194 associated with many human diseases, only a handful of plasma proteins are routinely used in clinica

195 Specifically, a handful of point-lights attached to the joints of a huma

196 However, only a handful of polymeric biomaterials are utilized today bec

197 ributions to circadian rhythmicity made by a handful of post-translational mechanisms, such as phosph

198 We identified a handful of potential recombination-associated sequence m

199 tion with ribosome profiling we identified a handful of previously unknown non-AUG initiation sites,

200 For example, marmosets are among only a handful of primates that, like humans, routinely pair bo

201 The use of a handful of probes has already revealed an amazing specif

202 defense funding has thus far produced only a handful of products for clinical development.

203 ical indications and directed against only a handful of protein and lipid kinases, leaving 70% of the

204 ase stretches of satellite DNA repeats and a handful of protein-coding genes that are monomorphic wit

205 s target proteins, but it can also degrade a handful of proteins in a limited and site-specific manne

206 In contrast to FTase and GGTase I, only a handful of RabGGTase inhibitors have been developed.

207 To date, only a handful of radiogenomics studies have been performed to

208 e autoantibodies (ACAAs) are pathogenic in a handful of rare immunodeficiencies.

209 Imine bond formation is one of a handful of reactions which define a discipline known as

210 information in living cells, but only for a handful of recombinant proteins at a time, whereas the l

211 n intergroup context is built around a small handful of recurrent interaction types.

212 ough the structure of many P450s and a small handful of redox partners are known, there is very littl

213 Overall, our results show that a handful of regions carry most of the mutations acquired

214 ure is of a highly subdivided species with a handful of relatively clonal groups (complexes) that, at

215 m the recent massive amplification of just a handful of repeat families, as shown in species with sma

216 tic means of factor delivery, and although a handful of replacement molecules have been identified, t

217 To date there is only a handful of reported cases of successful HSCT from siblin

218 While a handful of reports have demonstrated the potential of su

219 A handful of reports have shown that innate immune respons

220 ethics of placebo-controlled studies; only a handful of reports, however, have empirically addressed

221 less, the physiological properties of only a handful of retinal ganglion cell types have been studied

222 , radiation, intravesical agents) based on a handful of retrospective case series.

223 e time dimension, data are reduced to only a handful of scans around each peak apex.

224 cy syndrome (AIDS) epidemic has grown from a handful of sentinel observations in New York and Califor

225 ily interpretable when analyzing more than a handful of sequences.

226 revious one covering glycans released from a handful of serum glycoproteins, has more than 170 comple

227 The ubiquitin ligase Smurf1 can target a handful of signaling proteins for ubiquitin-mediated pro

228 Yet, its value has been measured only for a handful of simple lipids, and no simulation has so far d

229 Such instances have been inferred only for a handful of sites, and these lie almost exclusively withi

230 , these behaviors have only been tested in a handful of size dimorphic spiders.

231 Only a handful of small molecules that antagonize the action of

232 Fingerprinting of donor L1s revealed that a handful of source L1 elements in a tumor can spawn from

233 Although a handful of sparse vegetation records exists from middle

234 ficient replication origin modules to only a handful of species and restricts our understanding of or

235 ction with Lactobacillus is rare, and only a handful of species have been identified as being clinica

236 ly divergent or uniquely present in one or a handful of species, hampering efforts to determine the g

237 nging technology that is available only in a handful of species.

238 Despite this, only a handful of specific genes have been identified, and it i

239 Only a handful of spermatogenic genes are within this region, i

240 k drive, and prior drive are controlled by a handful of state parameters, which I hypothesize corresp

241 gy to make predictions constrained by just a handful of state variables, like total abundance or spec

242 However, there are currently only a handful of strategies for engineering such regulatory co

243 Yet there are only a handful of studies demonstrating control of electronic i

244 se variants are associated with disorders, a handful of studies documented an adaptive advantage conf

245 However, to date, only a handful of studies empirically tested its applicability

246 search has focused on candidate-genes with a handful of studies employing whole transcriptome approac

247 To date, only a handful of studies have directly determined the infectio

248 Only a handful of studies have examined the anatomy of the VOF

249 e and in contrast to transcriptomics, only a handful of studies in crop plants engaged with global pr

250 ) HDX-MS has become common, there are only a handful of studies reporting the systematic evaluation o

251 d DNA double-strand breaks, there are only a handful of studies that report precise editing of endoge

252 To our knowledge, this is one of only a handful of studies to document a nonmonotonic dose respo

253 af thermoregulation has been documented in a handful of studies, but the generality and origins of th

254 for cell cycle progression; however, only a handful of substrates are currently known.

255 s and hint at evolutionary processes where a handful of successful metabolic strategies are utilized

256 Only a handful of such peptides are known.

257 sms of sex determination is known for only a handful of such species, but, in those that have been in

258 nic wild-type lines provides evidence that a handful of synonymous substitutions supply cryptic varia

259 necessary level of detail exists for only a handful of systems.

260 Only a handful of target genes are known for these two factors

261 quamous cell carcinomas and pointed toward a handful of targetable alterations.

262 However, the mere handful of targets that have been identified barely begi

263 Unexpectedly, only the repression of a handful of TFs significantly affected transcriptomes, wh

264 No such vaccine currently exists, and only a handful of the hundreds of potential candidates in the p

265 on a regular basis, we would like to share a handful of the many lessons that we have learned in our

266 Only a handful of the more than 100,000 fungal species on our p

267 s to adopt the strategy of confirming only a handful of the most statistically significant results, a

268 To this day, only a handful of these compounds have been synthesized, but mo

269 H2 and PTP domains likely evolved earliest-a handful of these domains are found in premetazoan eukary

270 domain defines a large E3 family, but only a handful of these enzymes have been defined with respect

271 o 10% of a genome may encode TFs, but only a handful of these have been studied in detail.

272 omyces peucetius DnrI protein, one of only a handful of these proteins yet discovered, controls the b

273 h common diseases and complex traits, only a handful of these variants are validated to be causal.

274 quantitative data, on the other hand, only a handful of tools exist, and the computational burden is

275 ts; however, due to fairly large SEs, only a handful of trait pairs yielded statistically significant

276 r between species have been identified for a handful of traits, but the relationship between alleles

277 itted somatic cells using a combination of a handful of transcription factors, such as OCT3/4, SOX2,

278 not widespread, and are available at only a handful of transplant programs.

279 , most centers have performed no more than a handful of transplants.

280 A handful of trials are targeting non-CD19 hematological a

281 al conception just over a decade ago, only a handful of trials have been completed assessing the effi

282 A handful of tumor-derived cell lines form the mainstay of

283 , data are reduced from a full spectrum to a handful of unique ions for each chromatographic peak.

284 synthases identified in plants, less than a handful of unique sesquiterpene synthases have been desc

285 A handful of unique toehold activation mechanisms, includi

286 grees of freedom can be often described by a handful of variables.

287 skeletal structures helps explain how only a handful of vesicle types can mediate the numerous traffi

288 arkable progress, our understanding of how a handful of viral proteins can completely overrun the mul

289 a few strains of inbred mice infected with a handful of viruses with limited coding capacity.

290 olding studies are generally restricted to a handful of well-behaved proteins.

291 Despite their utility, only a handful of well-characterized regulators exist, limiting

292 it is apparent that altered expression of a handful of Wnt pathway proteins occurs in or regulates a

293 t the results are limited in scope to just a handful of woody species in one part of the state and ar

294 Currently, only a handful of XNA structures have been archived in the Prot

295 reas previous observations documented only a handful per day with lower average speeds of 200 kilomet

296 In the review period, only a handful reports on single nucleotide polymorphism analys

297 , these hundreds of options reduce to a mere handful, some of which turn out to be identical.

298 of repeats in any one array can range from a handful to several hundreds.

299 trated by many secreted proteins, but only a handful, tumor necrosis factor-alpha, IFN-gamma and IL-1

300 selected based on their activity, but only a handful with maximal activity have been traditionally id