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1 of open and closed conformational states of hUNG.
2 92 (63%) deaths were by hanging.
3 y from selected highly lethal means, such as hanging.
4 fic suicide rates: firearms, pesticides, and hanging.
6 rength, as measured by both weight-supported hanging (43% increase) and grip strength (25% increase),
7 nterestingly, mutations in human angiogenin (hANG), a member of the ribonuclease A (RNase A) superfam
9 have high dUTP levels, these cells have low hUNG activity, which may diminish the effectiveness of t
12 inhibitor of the ribonucleolytic activity of hANG, affected pathfinding by P19-derived neurons but no
14 rmal differentiation to study the effects of hANG-ALS variants on MN differentiation and survival.
16 to differentiate in the presence of hANG and hANG-ALS-associated variants internalize the wild-type a
20 induced to differentiate in the presence of hANG and hANG-ALS-associated variants internalize the wi
21 thods of suicide are preferred by young men: hanging and firearms in high-income countries, pesticide
22 from donors whose cause of death is suicidal hanging and to evaluate the outcome of the graft recipie
25 The ability of stem cells to self-renew has hung been attributed to an asymmetry in division that ge
27 boxyl-terminal region of these channels must hang below the pore much like the "hanging gondola" of v
28 ins, which initiate the response to ligand, 'hang' below the pore-forming part of the channel, attach
40 ype Celsr through its putative pro-region, a hanging drop assay reveals that cells from embryos with
42 d Tbx5 mRNA were first expressed at day 4 in hanging drop embryoid bodies, and adhesion of embryoid b
43 peptide complex readily crystallized by the hanging drop method in 15-18% polyethylene glycol 6000/1
46 imolar amounts of all five inhibitors in the hanging drop showed only the Raman signature of the comp
48 or oxidase enzyme are grown anaerobically by hanging drop vapor diffusion, under crystallization cond
51 microtissue spheroids, which is based on the hanging-drop network concept: The open microfluidic devi
58 llected from crystals in situ, in sitting or hanging drops, under the conditions used to grow the cry
59 Neonatal rats suspended in harnesses, limbs hanging freely, and injected with 100 mg/kg l-3,4-dihydr
60 of the FIDI method, 1-2-mm-diameter droplets hang from a capillary and undergo heterogeneous reaction
61 or phase which consists of a droplet that is hanging from a (conductive) pipet tip in the organic fil
62 looked more at impossible images with string hanging from below (unsupported), rather than above (sup
64 rogress has been largely limited to the "low hanging fruit" of mutations with obvious exonic coding o
65 focus on obvious areas of need, that is, low hanging fruit, provided early successes in our expanded
67 Matching these criteria, we identify "low-hanging fruits" for the inclusion in ESMs, such as basic
69 portion of the channel to enclose the Kv4.2 "hanging gondola" (a platform held beneath the transmembr
70 nels must hang below the pore much like the "hanging gondola" of voltage-gated potassium channels, bu
71 bedded part of the protein as a cytoplasmic "hanging gondola", and that ions gain access to the pore
72 mpairment (beam walking, pole climbing, wire hang, grip strength), sensorimotor skills (rotarod), mec
73 th a xanthene backbone and a carboxylic acid hanging group catalyzes the electrochemical production o
74 owever, only the former is observed when the hanging group is the acid, (HPX-CO2H)FeIII(OH), because
75 n and proton transfer from a carboxylic acid hanging group or an external acid to the meso carbon of
76 he HPX and HPD platforms with acid and ester hanging groups reveal that the introduction of a proton-
78 Steady-state fluorescence assays showed that hUNG has a much higher specificity constant (k(cat)/K(m)
79 oxia-induced cell death, but the variants of hANG implicated in ALS lacked the neuroprotective activi
81 e validity of PDF as an antibacterial target hangs, in part, on the ability of inhibitors to selectiv
83 ta suggest that the fleeting sliding form of hUNG is a distinct weakly interacting state that facilit
84 dings illustrate how the search mechanism of hUNG is not predetermined but, instead, depends on the c
87 hydroxynaphthalene (Fe/DHN) complexes on the hanging mercury drop electrode with catalytic enhancemen
93 proof of principle experiments, dropping and hanging mercury drop were observed as a function of the
96 enting yeast and ethanol than similar fruits hanging on trees, this transition may also be the first
97 that the kinetochore-associated Ska1 complex hangs on to depolymerizing microtubules and brings some
102 of injury deaths in order of frequency were hanging or suffocation, road traffic accidents, burns, d
104 to the porphyrin N core and the other cation hung over the N core through bonding with a carboxylate
105 nzymes such as human uracil-DNA glycosylase (hUNG) perform the initial step in the base excision repa
108 ng HPX (hanging porphyrin xanthene) and HPD (hanging porphyrin dibenzofuran) systems permit both the
112 tion and oxidation reactions (HER-HOR) using hanging strips of gas diffusion electrode (GDE) in solut
113 2.05; and 2008-2010: 2.69 times higher) and hanging/suffocation (males: 1996-1998, 1.24; and 2008-20
114 arm suicide rates declined, and the rates of hanging/suffocation for both males and females increased
116 hough the overall change in suicide rates by hanging/suffocation or other suicide methods did not cha
118 hanol in the open-field locomotor test, wire-hanging test, and righting-reflex test in male rats.
124 tes that asymmetric slip via collapse of the hanging wall is a natural consequence of coseismic defor
126 ated with deformation of mantle rocks in the hanging wall of subduction systems; an interpretation su
128 minantly subsidence of the basin side (fault hanging wall), with comparatively little or no uplift of
129 delling of the experiments confirms that the hanging-wall wedge undergoes pronounced rotation in one
132 ld-type (WT) mice using a unique two-kidney, hanging-weight model of renal bilateral IR (20 minutes o
133 the first time reports Cd(II) inhibition of hUNG which was due to replacement of the catalytic water
134 and hopping by human uracil DNA glycosylase (hUNG), which is an exemplar that efficiently locates rar
135 on is whether the facilitated search mode of hUNG, which includes both DNA sliding and hopping, chang
137 ield locomotion, rotarod motor coordination, hanging wire, footprint pathway, visual cliff, auditory
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