ライフサイエンスコーパス: harness

1 symmetrical and unsymmetrical alkynes can be harnessed.

2 e full potential of the dendralenes could be harnessed.

3 odies targeting 4-1BB have been developed to harness 4-1BB signaling for cancer immunotherapy.

4 surfaces, we show that bacteria are able to harness a variety of mechanisms to unpin contact lines,

5 Nayak and Metcalf have harnessed a bacterial Cas9 protein for genome editing in

6 Thus, the data indicate how harnessing a conformationally adaptive dimer can drive l

7 y for discrete membrane trafficking steps by harnessing a nucleotide-bound cycle.

8 mbretastatin D-1 by a conceptually new route harnessing a ring-contracting flash vacuum pyrolytic ext

9 also discuss possible future directions for harnessing adult neurogenesis for therapeutic use.

10 We developed a strategy to harness alkyl amines as alkylating agents via C-N bond a

11 In applied research, strategies to harness amino acid auxotrophy so as to block cancerous l

12 Here we harness an endogenous signaling pathway to regulate ther

13 of Developmental Cell, Parhad et al. (2017) harness an evolution-guided approach to define the genet

14 e that approximate number system (ANS) tasks harness an innate sense of number.

15 romolecular system offers the possibility of harnessing an equilibrium/nonequilibrium system in tande

16 These lessons should be harnessed and put into practice to build demand and trus

17 To harness antigen gene replication but avoid production of

18 The ability of these agents to harness antitumor immunity appears to be key for their s

19 ence changes with metabolic state, it can be harnessed as a label-free imaging tool with which to stu

20 bacterial CRISPR-Cas9 immune system has been harnessed as a powerful and versatile genome-editing too

21 s at the hexagonal ends of the crystals were harnessed as a powerful means to direct His-tagged fluor

22 arget and destroy invasive DNA and have been harnessed as a robust technology for genome editing.

23 the form of selective breeding has long been harnessed as a useful tool by humans.

24 ssically considered inert substrates, can be harnessed as synthons for use in reactions that form C-C

25 Here, we harness automated neuroimaging methods for cerebellar mo

26 The main challenge on the road ahead is to harness bigger health care data in ways that produce mea

27 Here we harnessed bioinformatics tools and a novel analytical fr

28 een manipulating the adaptive immune system, harnessing both the innate and adaptive arms of the immu

29 operties of integrin-ECM links, which may be harnessed by cells to control adhesion and migration.

30 port that crack formation can be effectively harnessed by elaborately restricting the drying of collo

31 nd among plant traits are increasingly being harnessed by empiricists and modelers to understand and

32 This frustration is harnessed by guest exchange to yield a very broad array

33 driving forces arising from dynamics can be harnessed by nature to evolve new allosteric ligand spec

34 Moreover, this plasticity can be harnessed by rehabilitative training to significantly pr

35 he genomic DNA, which would be rectified and harnessed by the forces from the interior wall of the vi

36 ectronic configuration changes that could be harnessed catalytically before excited state relaxation.

37 e we review leading HIV cure strategies that harness cell-mediated control against HIV in stably supp

38 An innovative approach to harness cellular dimensions reveals fundamental links be

39 to validate the present results, but also to harness clinical, biochemical, imaging, and genetic mark

40 nrich the knowledge that is learned; and (3) harness compositionality and learning-to-learn to rapidl

41 eet the goals of the Cancer Moonshot include harnessing computational power and architectures, develo

42 The challenge for immunologists is to harness computing and turn an avalanche of quantitative

43 ls described here highlight the potential of harnessing conformational order derived from PIC assembl

44 stem is thus a powerful tool that, if better harnessed, could significantly enhance the efficacy of c

45 the public but can also be used as a tool to harness creative thinking that can contribute to develop

46 y to exceed the limits of DIW 3D printing by harnessing deformation, instability, and fracture of vis

47 The wave energy harnessing device had on average 3.5 times higher impact

48 trode fabrication of various flexible energy harnessing devices.

49 esent a quantum error correction scheme that harnesses dissipation to stabilize a trapped-ion qubit.

50 ds on the paradigms used, as different tasks harness distinct capabilities to activate speech process

51 only begun to be explored in pioneering work harnessing DNA scaffolds to dictate the spacing, number

52 Harnessing "ecometric" measurement tools and emerging so

53 athway, which maintains proteostasis, can be harnessed effectively to protect oligodendrocytes and my

54 Microbial fuel cells harness electrical power from a wide variety of substrat

55 gical approaches to pain management, such as harnessing endogenous opioids for pain relief.

56 macological approaches to pain management by harnessing endogenous opioids for pain relief.SIGNIFICAN

57 ion in brown and beige adipocytes, where the harnessed energy is dissipated as heat in a process know

58 chological origins of human cooperation that harnesses evolutionary theories about the two major prob

59 Our approach provides a facile way to harness excitonic properties in low-dimensional semicond

60 l to mobilize into circulation, which may be harnessed for adoptive cellular therapy.

61 ve a tumor-suppressor function that could be harnessed for cancer therapy.

62 laboratory findings have also been recently harnessed for disease prevention.

63 This can be harnessed for early diagnosis of proteinopathies and for

64 Lachnospiraceae bacterium (LbCpf1) have been harnessed for eukaryotic genome editing.

65 y to the CRISPR RNA (crRNA), and it has been harnessed for genome editing technologies.

66 e V CRISPR-Cas system that has been recently harnessed for genome editing.

67 e Corynebacterium glutamicum, which has been harnessed for industrial production of amino acids, as w

68 e addition of radicals to isonitriles can be harnessed for initiating reaction cascades designed to o

69 kers, and they represent targets that can be harnessed for innovative therapeutic approaches.

70 ns to the operating parameters, which can be harnessed for metrological purposes.

71 is may allow the near-infrared photons to be harnessed for photovoltaics and photocatalysis.

72 ucleic acids and how these systems have been harnessed for precision genome manipulation in a wide ar

73 logy-dependent repair mechanisms that can be harnessed for recombineering and genome editing.

74 ilities by the length of the strand might be harnessed for stimulus-responsive applications in DNA sc

75 ngle-crystalline packing motif, which can be harnessed for strong intermolecular electronic coupling.

76 ates suppressive human Tr1 cells that may be harnessed for the control of allergic diseases.

77 complementary to the guide RNA and has been harnessed for the development of a variety of new techno

78 simplified cloning, these have not yet been harnessed for the high-throughput generation of expressi

79 -axial strain conditions; such states may be harnessed for the realization of qubits.

80 cts of STING on T cells could potentially be harnessed for therapeutic applications.

81 ost-a relationship that could potentially be harnessed for therapeutic benefits.

82 T cells as alternative APCs, which could be harnessed for therapeutic interventions and vaccine desi

83 Before these cells can be harnessed for therapeutic purposes, it is necessary to u

84 member of the COMPASS family, which could be harnessed for therapeutic regulation of signaling in hum

85 pecific delivery of T cell antigens could be harnessed for tolerance induction in clinical settings.

86 palindromic repeat (CRISPR) system, recently harnessed for transcriptional regulation in various hete

87 c tunnel junctions and show that STDP can be harnessed from inhomogeneous polarization switching.

88 is realized that can be dynamically tuned by harnessing geometric and magnetic nonlinearities in the

89 HBV uses multiple pathways to harness host innate immunity to enhance its replication.

90 By harnessing host-guest optochemical interactions of funct

91 Harnessing humoral and innate cellular responses has bec

92 Harnessing immune system to treat cancer requires simult

93 ntrol ion transfer, in a process that can be harnessed in applications such as batteries, smart windo

94 ells to adopt migration patterns that may be harnessed in health or exploited in disease.

95 ML nuclear bodies are druggable and could be harnessed in other conditions.

96 n bonding also allows site-selectivity to be harnessed in reactions of polyunsaturated compounds, sin

97 Our findings illuminate how ATP energy is harnessed in the NBDs in a two-stroke cycle and elucidat

98 These findings open the possibility of harnessing in vivo imaging to determine the contribution

99 These selected modifications harnessed innate biodistribution pathways through the st

100 rea, our understanding of how to control and harness it and dial-up specific properties is still in i

101 Harnessing it by study of its passage through organic ma

102 s of the radical were changed drastically by harnessing its binding energy to the metalloprotein.

103 g health care in conflict and to effectively harness legal mechanisms to discourage future perpetrato

104 Harnessing lipogenic pathways and rewiring acyl-CoA and

105 ail, an untargeted metabolomic approach that harnesses mass spectral networking was used to assess th

106 By harnessing multiomics approaches, we may gain valuable i

107 Systems genetics, a process of harnessing multiple levels of component trait informatio

108 Here we harness narrow-range temperature cycling to cause repeat

109 escribe a computational tool, demuxlet, that harnesses natural genetic variation to determine the sam

110 The goal of the TFT is to harness naturally occurring mutations in the mitochondri

111 ectacular advancements have been achieved to harness nature's ability to cure diseased tissues and or

112 the control of Arc that could be targeted to harness neuroplasticity for clinical applications.

113 lly broadened, and researchers have begun to harness new approaches to explore how rodents and humans

114 proteinase function should inspire more work harnessing new technologies such as imaging, proteomics,

115 s to prevent or target metastatic disease by harnessing NK cells.

116 Biological systems have evolved to harness non-equilibrium processes from the molecular to

117 r TBV effects with a novel allometric method harnessing normative scaling rules for subcortical size

118 le oxidation chemistry demands strategies to harness O2 as a terminal oxidant.

119 The metal cluster in each of these MMOs harnesses O2 to functionalize the C-H bond using differe

120 morphous NiFe-LDH/C nanohybrid, allowing the harness of the high intrinsic activity of NiFe-LDH due t

121 e effect on yield, but hindered simultaneous harnessing of below- and above-ground ecosystem services

122 Harnessing of Morita-Baylis-Hillman (MBH) carbonates of

123 of scalable bottom-up approaches stymies the harnessing of smart tissues' biological, mechanical and

124 Understanding and therapeutic harnessing of the role of stroma in cancer restraint may

125 roups offer complementary expertise that, if harnessed, offer to accelerate our understanding of aque

126 s paper presents a statistical framework for harnessing online activity data to better understand how

127 s for personalized therapeutics will require harnessing pheno-genotypic cell-level data quantitativel

128 ayers offer a promising strategy to directly harness photon upconversion via triplet-triplet annihila

129 eres and imply that it is most beneficial to harness plasticity in both hemispheres in neurorehabilit

130 skill learning may be beneficial because it harnesses plasticity in the ipsilateral hemisphere.SIGNI

131 karyotic protein with prion properties which harnesses prion-like transmission to regulate protein fu

132 Harnessing proximity-enabled reactivity of an unnatural

133 In this study, we harness PTS by rendering association of split intein fra

134 We harnessed publically available information from the Psyc

135 Engineering apparatus that harness quantum theory promises to offer practical advan

136 achieved via a redox-relay mechanism, which harnesses radical intermediates for selective C-N bond c

137 hemists with the unprecedented capability to harness reactive radicals through discrete, single-elect

138 'template-switching' lentiviral vector that harnesses recombination events during reverse-transcript

139 roaches modulate resolution and propose that harnessing resolution concepts could potentially lead to

140 life via respiratory failure, the ability to harness respiratory motor plasticity to improve breathin

141 t to evaluate their relevance for efforts to harness science in support of sustainability in the deve

142 ar the as-fabricated photovoltaic textile to harness solar energy for powering small electronic devic

143 , it is imperative to design strategies that harness specialized DC subsets in situ.

144 Harnessing stem carbohydrate dynamics in grasses offers

145 tosolic release of the entrapped agents that harnesses sub-lethal photodynamic therapy (PDT) using a

146 The goal of these new approaches is to harness subtype-specific insights into cancer and immune

147 ll-molecule natural product, hinokitiol, can harness such gradients to restore iron transport into, w

148 By harnessing such low-cost and versatile deuterated substr

149 rapid, point-of-care diagnostic device which harnesses surface acoustic wave (SAW) biochips, to detec

150 his study reveals an adaptive mechanism that harnesses synergistic paracrine signalling via IL-6/8, w

151 In the past decade, the power of harnessing T-cell co-signaling pathways has become incre

152 oorthogonal tetrazine uncaging reaction that harnesses tetrazine reactivity to unmask vinyl ether cag

153 The ability to harness the "lifetime" of hot-carrier gases with nanosca

154 Immunotherapies that harness the activity of the immune system against tumors

155 duce class IIa HDAC inhibition as a means to harness the anti-tumour potential of macrophages to enha

156 proach for production of hybrid varieties to harness the benefits of hybrid vigour.

157 In this work, we harness the capacity of fluorescence activated cell sort

158 mpatible, mechanically flexible, and able to harness the chemical energy available inside biological

159 in plant science will accelerate efforts to harness the chemical wealth of the plant kingdom.

160 ally, we established a database and tools to harness the cross-linked interactions we observed as mol

161 ls are being conducted with the objective to harness the donor immune system to protect the transplan

162 In the current study, we harness the draining properties of the lymphatic system

163 In this study, we harness the electric and magnetic resonances of such ant

164 tte (ABC) transporters of the exporter class harness the energy of ATP hydrolysis in the nucleotide-b

165 r Cell, cast light on how cohesin regulators harness the energy of ATP hydrolysis to open the cohesin

166 ATLs harness the energy of GTP hydrolysis to initiate a serie

167 Here, we harness the energy-minimization nature of nanomagnetic s

168 latory network, very few of them are able to harness the extra expression states present in single-ce

169 es a conformation that enables the enzyme to harness the free energy of ADP binding to drive ATP rele

170 Therefore, we are yet to harness the full potential of redox enzymes for the deve

171 A biocatalytic approach could harness the high affinity of enzymes for their substrate

172 Here we harness the high resolution of molecular dynamics simula

173 to the activation of bystander effects that harness the immune system against the tumor, attacking n

174 the host immune system, and discusses how to harness the immune system effectively as a therapeutic t

175 suppress CNS immune mechanisms, while others harness the immune system to clear deleterious products

176 Finally, we harness the impedance signature of unstimulated T cells

177 tion protocols are indeed necessary to fully harness the information-theoretic resources contained in

178 or UPS activity may provide opportunities to harness the innate immunity of epithelia against infecti

179 Our dual strategy can be used to harness the landrace diversity of plants and animals.

180 s are attractive model systems with which to harness the maximum magnetic anisotropy of Dy(III) ions.

181 er understanding of these links will help us harness the potential therapeutic benefits of autophagy

182 hitecture to a given task is needed to fully harness the power of CNNs for computational biology appl

183 Yet many radiologists struggle to harness the power of cost measurement and cost managemen

184 cally encoded, single-protein reporters that harness the power of molecular biology to visualize spec

185 zation, and imaging have begun to more fully harness the power that such large data stores can provid

186 How to harness the private sector to improve population health

187 The proposed system presents a solution to harness the same amount of solar products (crops, electr

188 Here we harness the specificity and rapid-acting properties of b

189 ased methods like ConsensusDriver promise to harness the strengths of different driver prediction par

190 cgMLST offers an opportunity to harness the tremendous power of next-generation sequenci

191 Here, we harnessed the endogenous regenerative capacity of the ze

192 In this study, we have harnessed the power of bioorthogonal tethering to SNAP a

193 ing in specific cell populations in vivo, we harnessed the power of DREADD (designer receptors exclus

194 th you: Xia, Burns, Martinez, and co-workers harnessed the ring strain of ladderenes to enable both t

195 Trim-Away harnesses the cellular protein degradation machinery to

196 Our approach harnesses the native targeting and activation mechanism

197 The proposed VO2 oscillator network harnesses the natural analogue between optimization prob

198 The antenna-reactor geometry efficiently harnesses the plasmon resonance of aluminum to supply en

199 script]) for next-generation sequencing that harnesses the specificity of HIV-directed priming to ena

200 st that bold approaches to drug development, harnessing the adaptive properties of the immune-microen

201 a physically controlled drug delivery method harnessing the biology of endothelial adherens junction

202 Receptor mediated transcytosis harnessing the cellular uptake and transport of natural

203 accuracy of the technique can be enhanced by harnessing the central limit theorem.

204 complish this by creating materials aimed at harnessing the complex interplay between quantum wavefun

205 Here we show that, by harnessing the dual signaling and antibiotic features of

206 miRNA world, and a systematic effort toward harnessing the enormous therapeutic potential of these s

207 etargeting stands as a promising approach to harnessing the exquisite tumor-targeting properties of a

208 s across the inner mitochondrial membrane by harnessing the free energy generated by the reduction of

209 nes generating directional pulling forces by harnessing the mechanically purposeful motion of molecul

210 By harnessing the MN's reversible swelling/deswelling prope

211 e strategies present a critical step towards harnessing the myriad of potential applications of MOFs

212 By harnessing the one-electron chemistry of photoredox cata

213 ent engineering efforts have centered around harnessing the potential of these microbial biofactories

214 ntly, there has been substantial interest in harnessing the power of antibody-mediated catalysis agai

215 he diversity across populations, and studies harnessing the power of genetic and genomic approaches t

216 Harnessing the power of genome editing may usher in a se

217 avenues to pain prevention and treatment by harnessing the power of the mind.

218 tific communities are probably not yet fully harnessing the power of these genetic discoveries.

219 Harnessing the power of this technology, hospitals can c

220 Harnessing the printing and postprinting parameters allo

221 Harnessing the reverse reaction has the potential to all

222 ponses against Mycobacterium tuberculosis by harnessing the SET8-NQO1/TRXR1 axis with its specific an

223 Policymakers should explore methods of harnessing the surge of novel TOAMs to increase price co

224 By harnessing the temporal specificity of optogenetics, we

225 of crowdsourcing are not restricted only to harnessing the time, labor, and funds from the public bu

226 densities up to terahertz frequencies, thus harnessing the unique properties of topological material

227 ates opportunities for studying magnetism by harnessing the unusual features of atomically thin mater

228 Harnessing the upper critical solution temperature of su

229 This SDSM operates by harnessing the wettability contrast and the geometry of

230 To harness their extraordinary stretchability and microstru

231 To harness their full biosynthetic potential, it is importa

232 y applications, previous research has yet to harness their potential burning efficiency for enhanced

233 gene function is of increasing importance to harness their potential to produce plants with novel tra

234 How can we best harness their power?

235 re research directions for understanding and harnessing their ability to specifically control gene ex

236 ion and documentation of diagnostic imaging, harnessing their potential requires efficient and automa

237 or preventing bubble related pathologies and harnessing their potential therapeutic benefits.

238 ed with the aim of finding new materials and harnessing their unique and tunable electronic and optic

239 ligands integrated into porous materials to harness them for gas storage and separations, chemical s

240 elp patients and develop new treatments that harness these surgical effects with less invasive interv

241 Here, we harness these tools to generate a brain-scale circuit mo

242 Harnessing these cooperative interactions to catalyse re

243 However, less progress has been made in harnessing these data to reveal new therapies.

244 By harnessing these datasets, we defined developmental ages

245 Harnessing these dechlorinating processes could provide

246 A major challenge to harnessing these natural products is that they are found

247 and there has been an increasing interest in harnessing these receptors to augment tumor immunity.

248 ropic or direct adhesive interactions, or by harnessing "third-party" molecular anchors to crosslink

249 In order to harness this degradative response therapeutically, we al

250 schemia, but previous studies have failed to harness this finding for therapeutic use.

251 mory in mice and identify molecular tools to harness this pathway for therapeutic purposes.

252 To fully harness this potential, we must accurately know the X-ra

253 e development of translational strategies to harness this process for neuronal repair.

254 Here, the authors harness this unpredictability to develop a memristor-bas

255 We harnessed this reactivity to generate a broad range of s

256 1 binds the 5' SS and suggest that E complex harnesses this mechanism to stimulate recruitment and re

257 Thus, by harnessing this homeostatic regulatory mechanism, ES-62

258 er and aging with the long-term objective of harnessing this information for the advancement of patie

259 When harnessed, this system has the potential to write arbitr

260 By harnessing three indolyne isomers, six isomeric indole t

261 Thus, harnessing time- and compartment-specific differences in

262 The versatility of the method was harnessed to access a selenophene-annulated expanded hel

263 Rapid chemical reactions can be harnessed to achieve facile de novo synthesis of lipid m

264 nent of bacterial adaptive immunity has been harnessed to address important biological questions usin

265 ical targeting of HDAC3 could potentially be harnessed to alter systemic fuel metabolism and exercise

266 regulate and enhance efferocytosis could be harnessed to combat infection and chronic inflammatory c

267 en doping, solubility, and morphology can be harnessed to control crystallinity, create doping gradie

268 This property could be harnessed to develop more effective vaccines against enc

269 fore, drug interaction fingerprinting may be harnessed to differentiate drug identities.

270 ntegrin activation from a biomaterial can be harnessed to direct therapeutic vessel regeneration and

271 e demonstrate how this entropy change can be harnessed to drive PGNPs into spatially organized domain

272 apeutic delivery of senescent cells could be harnessed to drive tissue regeneration.

273 f spin-orbit torque and thermal noise can be harnessed to enable probabilistic inference in a plethor

274 ic CD8+ T cells and how these cells might be harnessed to greater effect toward achieving viral eradi

275 Im25 illustrating how this technology can be harnessed to identify alternatively polyadenylated RNA.

276 activity; this property could be potentially harnessed to improve drought tolerance in plants.

277 tidylcholine-based unilamellar liposomes are harnessed to investigate membranotropic effects of alkyl

278 Chemical and biological tools are harnessed to investigate the impact of spatial factors f

279 biosynthetic demands, metabolic pathways are harnessed to maximize proliferation and effector molecul

280 xygen deprivation, a mechanism that could be harnessed to minimize hypoxic damage in human disease.

281 d suggest that this function of FOXO1 can be harnessed to overcome chemoresistance in cancer.

282 hese rapidly evolving technologies are being harnessed to probe combinatorial gene functions in funct

283 endogenous cellular mechanisms, which may be harnessed to produce neuroprotection.

284 h its formidable political influence, can be harnessed to promote health initiatives in areas ranging

285 ven disturbance to fluid flows, which can be harnessed to promote mixing for various electrokinetic m

286 its endogenous CRISPR-Cas system I-B can be harnessed to repress gene expression in archaea.

287 us but dormant homeostatic mechanisms can be harnessed to restore synaptic strength despite C9orf72 p

288 rther insight into such differences might be harnessed to selectively promote regulatory T cells (Tre

289 and gene annotations are growing and can be harnessed to shed a new light on psychiatric disorders.

290 the lipid membrane, which can be ultimately harnessed to synthesize ATP.

291 cy patterns suggest that polyamides could be harnessed to target loci within regions of the genome th

292 vo control and whether it may be selectively harnessed to target pathogens and/or tumors isunknown.

293 er, these results showcase the potential for harnessing translation-reprogramming mechanisms for synt

294 eutic benefits beyond tumoricidal effects to harness tumor-specific, durable, and systemic antitumor

295 hemical energy produced by ATP hydrolysis is harnessed via the concerted motion of the protein-protei

296 Inspired by Nature, we harness virus-like assemblies as artificial nanocompartm

297 Electrically excitable cells harness voltage-coupled calcium influx to transmit intra

298 Here, we harnessed whole-genome sequencing data to estimate the m

299 Such tuning is harnessed within terahertz quantum cascade lasers to rev

300 is little mechanistic insight into how cells harness ZBTB33 transcriptional capabilities to promote a