ライフサイエンスコーパス: harsh

1 on, Salmonella must successively survive the harsh acid stress of the stomach and multiply into a mil

2 y relevant stressors--such as heat, mild and harsh acidic conditions, storage and proteolytic degrada

3 d related species may be able to combat this harsh acidic environment which contains reactive oxygen

4 tors induces doping without encountering any harsh activation.

5 ty in multiple cycling tests under prolonged harsh adsorption-desorption conditions.

6 RG I as compared to the galactan ones under harsh alkaline conditions.

7 Traditional methods utilize harsh and laborious sample dehydration procedures, often

8 haracter attributes, by increasing perceived harsh and lingering bitterness, astringency, and bittern

9 purely climate, southern countries are less harsh and more predictable than northern countries.

10 ductionist laboratory settings generalise to harsh and noisy natural environments in which genetic va

11 Harsh and unpredictable ("desperate") ecologies induce f

12 ver, oral DNA delivery is complicated by the harsh and variable conditions encountered throughout gas

13 ors and which enables them to be active in a harsh and variable environment.

14 hop acid contents were perceived as having 'harsh' and 'progressive' bitterness, whilst beers that h

15 suggests that North American deserts, while harsh, are not uniform in the challenges they present to

16 reatment technique preserves cartilage under harsh articulation conditions, showing promise as a mate

17 However, the fact that both benign and harsh, as well as stable and fluctuating, environments c

18 ligands protect the nanostructures from the harsh biological environment, while allowing coupling to

19 ognition abilities and the high stability in harsh chemical and physical conditions.

20 The harsh chemical conditions involved in the isolation of f

21 Despite the harsh chemical conditions of stored urine (pH > 9 and to

22 ution using visible light while withstanding harsh chemical environments.

23 reby avoiding the use of organic solvents or harsh chemical procedures.

24 functionalities to their surfaces, although harsh chemical treatments can lead to their break-up int

25 For example, cryogenic storage imposes very harsh chemical, physical, and mechanical stresses on bio

26 Harsh chemicals and heat activation are effective for st

27 e procedure that does not require the use of harsh chemicals or any electrode/enzyme pre-treatments.

28 In humans and other animals, harsh circumstances in early life predict morbidity and

29 torpor) to cope with reduced food supply and harsh climates [1, 2].

30 C. burnetii has evolved to replicate in this harsh compartment by a mechanism involving acid activati

31 000 potential cycles to 1.4 V vs RHE, a very harsh condition for ORR electrocatalysts where state-of-

32 tion through iron sequestration, even in the harsh condition of urine acidification.

33 ased therapies are selective, do not require harsh conditioning, and do not have a risk of graft-vers

34 However, under harsh conditions (enzyme:inhibitor = 1:2000), OXA-24 was

35 ucture of ILs, and (3) the sustainability in harsh conditions (high temperature or humidity) and inte

36 Effective control of phase growth under harsh conditions (such as high temperature, highly condu

37 ilver complex and modest heating compared to harsh conditions and extra promoters including directing

38 ently require the use of alkyl iodides under harsh conditions and high pressures of CO.

39 approach to improve their stability against harsh conditions and provide controlled release for food

40 als often requires toxic starting compounds, harsh conditions and/or complex procedures.

41 However, harsh conditions are traditionally required for the effe

42 SsoPox showed resistance to harsh conditions demonstrating that it is an extremely a

43 hoice for sialic acid stabilization, but the harsh conditions during permethylation may lead to the d

44 vailable CAs are woefully inadequate for the harsh conditions employed in most of these processes.

45 ow-temperature activity, while surviving the harsh conditions encountered at high engine loads, remai

46 rsors typically require inert atmosphere and harsh conditions for their generation and use.

47 These harsh conditions generally lead to sample loss and DNA d

48 To survive, they must resist the harsh conditions in phagocytes (including acidic pH, ele

49 molecules involves catalytic reactions under harsh conditions in the liquid phase (e.g., temperatures

50 Settler cells are better able to withstand harsh conditions like drought and alkaline pH.

51 ducted in RNase-free solutions, prior to the harsh conditions of FISH, in order to preserve protein a

52 hat is resistant to corrosion even under the harsh conditions of start-up, shut-down, and/or hydrogen

53 ctors frequently found to be unstable in the harsh conditions of the bloodstream, and viral vectors o

54 mily of nanoparticles that can withstand the harsh conditions of the stomach and intestine, avoid sys

55 t Fe-AAPyr can be utilized in MFCs under the harsh conditions of wastewater.

56 show sensitivity to side reactions, and need harsh conditions or long reaction times.

57 methods are useful, but they are limited by harsh conditions or the need to prepare reagents.

58 man anionic peptide that is active under the harsh conditions present in human sweat.

59 Due to the harsh conditions required to produce 11 and 12, it is ex

60 e pendant arms are kinetically inert in very harsh conditions such as 2 M HCl, with no dissociation b

61 adaptation of cancer cells to growth in the harsh conditions that are frequently encountered within

62 or example, when C. elegans larvae encounter harsh conditions they can reversibly halt the passage of

63 Current catalysts require harsh conditions to effect HDO, decreasing the process e

64 g alkali or transition metal reagents and/or harsh conditions to facilitate the process.

65 hes which are structure-compromising and use harsh conditions to target, and oxidize and/or remove pa

66 uce these oxyanions often require the use of harsh conditions, but microorganisms can efficiently red

67 During winter, trees have to cope with harsh conditions, including extreme freeze-thaw stress.

68 the current routes to these products involve harsh conditions, limiting the variety of functionality.

69 ccomplished using physical methods involving harsh conditions, limiting their applicability in numero

70 HfO2 TRRAM shows reliable performance under harsh conditions, such as high oxygen partial pressure,

71 mers were surprisingly stable in the face of harsh conditions, suggesting that junk Env is unlikely t

72 Under harsh conditions, the enzyme in SEE exhibits better perf

73 ery few proteases are able to withstand such harsh conditions, with pepsin being the best-known excep

74 BChE from denaturation and degradation under harsh conditions.

75 pment into dauer, a diapause that withstands harsh conditions.

76 the other hand, it was rapidly reduced under harsh conditions.

77 , as indicated by washing the membrane under harsh conditions.

78 able over time and disassemble with force or harsh conditions.

79 rtain microorganisms can adapt even to these harsh conditions.

80 e peptide interactions that resist force and harsh conditions.

81 aim at designing enzymes that can work under harsh conditions.

82 diagnostic and bioimaging platform for very harsh conditions.

83 ndicating the attempt to form biofilms under harsh conditions.

84 al stability suitable for applications under harsh conditions.

85 in biological functions in order to survive harsh conditions.

86 matrix (ECM) without the involvement of any harsh conditions.

87 a highly endothermic process conducted under harsh conditions; hence, the main difficulty resides in

88 lled primarily by injection of opioids, with harsh criminalisation of drug use that has resulted in e

89 (<6 microW), and mechanical stability under harsh deformations.

90 ligation auxiliaries that are removed under harsh denaturing conditions and have limited applicabili

91 ence reduce the time spent foraging in their harsh desert environment.

92 lly critical during preparation of worms for harsh desiccation (preconditioning) and during the entry

93 usion bodies, which can be solubilized using harsh detergents or urea; however, traditional methods o

94 ed in gentle detergents but are disrupted in harsh detergents such as Triton X-100.

95 ed for his use of electrical stimulation and harsh disciplinary procedures in popular and scientific

96 ms of ethanol wetting and ethanol removal by harsh drying condition.

97 cability of AlN TRRAM for future transparent harsh electronics.

98 nd may serve as an evolutionary precursor to harsh elemental soils and environments.

99 endolithic microorganisms are adapted to the harsh environment and capable of metabolic activity at i

100 that structure bacterial communities in this harsh environment are not known; however, insights from

101 managed to demographically establish in this harsh environment by addressing a central question: did

102 odulate host immune responses to establish a harsh environment for clinically important bacterial pat

103 Fuel is a harsh environment for microbial growth.

104 nce that natural selection in the relatively harsh environment of Chirikof Island has further impacte

105 However, the instability of palladium in the harsh environment of fuel-cell cathodes renders its comm

106 uipped to resist chemical degradation in the harsh environment of mucosal surfaces and enzymes of hos

107 ole in biofilm formation, protection against harsh environment of the gut, and colonization of the ho

108 nd rapidly to nutrient limitation within the harsh environment of the phagosome.

109 After travelling through the harsh environment of the stomach lumen, H. pylori coloni

110 l diversity may also be a consequence of the harsh environment within which we find these charismatic

111 s performance by mass overload, and create a harsh environment, which reduces biological activity.

112 nds is essential for animals to survive in a harsh environment, yet the signaling pathways initiating

113 ay reflect adaptations for surviving in this harsh environment.

114 on, survival, and eventually metastasis in a harsh environment.

115 ells to survive an unpredictable change to a harsh environment.

116 mperatures significantly limit their uses in harsh-environment energy storage devices, e.g., automobi

117 lved a number of strategies to cope with the harsh environmental changes during mammalian infection.

118 To survive in the harsh environmental condition the plant species have dev

119 To protect anthocyanins against harsh environmental conditions (e.g., pH and temperature

120 also performs reliably under four different harsh environmental conditions and 2 MeV proton irradiat

121 It has an excellent adaptability to harsh environmental conditions and plays an important ro

122 d immunity during development if they expect harsh environmental conditions as an adult or it might s

123 Harsh environmental conditions cause Caenorhabditis eleg

124 ant but potentially infective parasites from harsh environmental conditions until their ingestion by

125 he degradation of plastics after exposure to harsh environmental conditions, and iii) detect counterf

126 eloped a variety of mechanisms for surviving harsh environmental conditions, nutrient stress and over

127 gnition element due to their stability under harsh environmental conditions, were synthesized using t

128 e-scale grid storage, and sensors located in harsh environmental conditions, where performance at tem

129 cies richness along gradients from benign to harsh environmental conditions, which supports the hypot

130 potential as an optical sensing element for harsh environmental conditions.

131 nges of body length may occur in response to harsh environmental conditions.

132 ed performance for sensing, especially under harsh environmental conditions.

133 pe considered especially well adapted to the harsh environmental extremes of the Great Plains.

134 beetles with protection against a variety of harsh environmental factors.

135 quely stable cell forms, highly resistant to harsh environmental insults.

136 hell also protects the functional NP core in harsh environments (down to pH 1) while still showing th

137 bstances, thereby improving their fitness in harsh environments and contributing to resistance agains

138 ial roles in protection of the bacteria from harsh environments and toxic compounds, including antibi

139 le in protecting Gram-negative bacteria from harsh environments and toxic compounds.

140 (GI) tract is highly challenging due to the harsh environments any drug- delivery vehicle must exper

141 Hydrophobic materials that are robust to harsh environments are needed in a broad range of applic

142 nematode Caenorhabditis elegans can adapt to harsh environments by undergoing a whole-animal change,

143 cuous species that inhabits a large range of harsh environments including flooded habitats and varyin

144 d whether species inhabiting low-resource or harsh environments invest more in defense, as predicted

145 grow, and how they avoid destruction in the harsh environments of star-forming galaxies.

146 pave new paths for materials applications in harsh environments requiring higher stabilities.

147 muCSs) are more suitable for operation under harsh environments such as high temperature and corrosiv

148 Organisms from harsh environments such as the Brazilian semiarid Caatin

149 performance of Cu mesh hybrid electrodes in harsh environments suggests they have strong potential f

150 sing, and quantum photonics, particularly in harsh environments that are challenging for other device

151 Harsh environments within damaged and diseased tissues a

152 sumption of its grain and ability to grow in harsh environments, but remains understudied in terms of

153 that inbreeding depression is more severe in harsh environments, but the few studies of in situ wild

154 appears to be frequent during adaptation to harsh environments, including the colonization of animal

155 ce, critical for timely protein synthesis in harsh environments, is accompanied by a drastic reductio

156 Designing materials to function in harsh environments, such as conductive aqueous media, is

157 e perennial weeds to adapt and survive under harsh environments, which will be beneficial for address

158 treme stability that allow their survival in harsh environments.

159 cids might play major roles in adaptation to harsh environments.

160 he promising applicability of HfO2 TRRAM for harsh environments.

161 nderappreciated selective force on plants in harsh environments.

162 the capsid thus favouring phage survival in harsh environments.

163 and utilize urease, which limit their use in harsh environments.

164 ve focus on deficits in people who come from harsh environments.

165 by polymeric modifiers, these deteriorate in harsh environments.

166 ustain hydrophobicity even after exposure to harsh environments.

167 al diodes for performing logic operations in harsh environments.

168 s may have especially strong consequences in harsh environments.

169 ter understanding of how bacteria survive in harsh environments.

170 s many secondary metabolites to help survive harsh environments.

171 e-rich conditions and mitigating exposure to harsh environments.

172 otic regulatory network topology to adapt to harsh environments.

173 n enable microbial communities to survive in harsh environments.

174 nd portable electrochemical immunosensors in harsh environments.

175 are of great interest for applications under harsh environments.

176 To understand better how MTB adapts to the harsh environs of the human host, we performed a global

177 atom production rates, short half-lives, and harsh experimental conditions limited the number of expe

178 volving multiple Diels-Alder reactions under harsh extended reaction conditions.

179 ility and increasing protein longevity under harsh extracellular conditions.

180 Viruses must remain infectious while in harsh extracellular environments.

181 als to foster communication between cells in harsh extracellular environments.

182 ols are able to explain the influence of the harsh FCC processing conditions (e.g. steam) and the pre

183 leakages for the electrode channels even at harsh flow rates of up to 40.0 mL min(-1).

184 opulations because they were confronted with harsh, fluctuating environmental conditions.

185 ribute to transmission and resistance in the harsh food environment and sporulation is essential for

186 oparticles can improve drug stability in the harsh gastrointestinal (GI) tract environment, providing

187 function in H. capsulatum replication in the harsh growth environment of the macrophage phagosome.

188 litate establishment of ericaceous plants in harsh habitats.

189 eoid roots of nonmycorrhizal species such as harsh hakea (Hakea prostrata).

190 Harsh hakea thrives in the nutrient-impoverished, ancien

191 Proteoid roots from Pi-starved harsh hakea were analyzed over 20 d of development to co

192 ignificant amounts of acrylamide during less harsh heat treatment (121 degrees C for 30min).

193 These include harsh heat treatments, chemical modifications or biocata

194 trates outstanding long-term stability under harsh HER cycling conditions.

195 nd porosity being retained after exposure to harsh humid conditions (90% relative humidity at 353 K).

196 s must also be able to withstand the initial harsh hydrogen peroxide treatment necessary for hydroxyl

197 more nurturant-involved parenting, and less harsh-inconsistent parenting, as a consequence of the in

198 ion under simulated conditions that resemble harsh industrial environments.

199 in protecting the underlying tissue from the harsh intestinal environment, is completely renewed ever

200 le to accomplish their tasks of transport in harsh intracellular circumstances, stochastic studies on

201 The harsh irradiation environment poses serious threat to th

202 ndividuals' immediate living conditions less harsh, leading to slower life strategies.

203 are not expected to find any application in harsh loading conditions.

204 stances of diseases of that organ system and harsh mechanical and physical conditions any such system

205 Aggregates created by harsh mechanical stress showed the largest number of sub

206 e absolute true rate, the most important and harsh metrics for the multi-label systems.

207 tation site for human pancreatic islets is a harsh microenvironment for islets and it lacks the abili

208 subsp. paratuberculosis is known to survive harsh microenvironments, especially those inside activat

209 m of inadequate value under a broad range of harsh non-biological conditions, and how to reconstitute

210 The harsh northern conditions may impose greater selective p

211 pes of touch stimuli: gentle (innocuous) and harsh (noxious/painful) touch, however, the underlying m

212 Rigorous parameter tuning and a harsh null are used to minimize false positives.

213 may result from the selective pressure of a harsh nutrient-deprived microenvironment.

214 t also presents outstanding durability under harsh OER cycling conditions, and its stability is much

215 n modern electronics and power modules where harsh operating conditions are present.

216 duce bioactive components and be adapted for harsh operating environments that reflect in vivo condit

217 ve revealed that Drosophila larvae can sense harsh or gentle touch with dendritic arborization (da) n

218 egion central for classifying a detergent as harsh or mild, but the detergent aggregation number migh

219 t methods to make boronic acids often employ harsh or wasteful reagents to prepare boronic acid deriv

220 while protecting the nanocarbon product from harsh oxidizing environment.

221 to secondary materials over time due to the harsh, oxidizing conditions required to drive oxygen evo

222 rtner sexual violence, childhood trauma, and harsh parenting (smacking their children as a form of di

223 Furthermore, animal studies suggest that harsh parenting affects the expression of genes by epige

224 al education, unstable family structure, and harsh parenting and TL.

225 s during pregnancy reported engaging in more harsh parenting behaviors when their children were toddl

226 ds of child maltreatment and mother-reported harsh parenting behaviors.

227 as a risk factor for child maltreatment and harsh parenting during their children's first and second

228 intentions signal risk for maltreatment and harsh parenting of her child during the first years of l

229 economic conditions had a stronger impact on harsh parenting than improvements in conditions, and tha

230 trauma, physical intimate partner violence, harsh parenting, and other factors.

231 ns, rather than current conditions, affected harsh parenting, that declines in macroeconomic conditio

232 e effects of the Great Recession on maternal harsh parenting.

233 iapausing stage that allows survival through harsh periods).

234 However, the harsh permeabilization conditions also led to the leakag

235 sustained at these anodes for many hours in harsh pH and oxidative environments whereas comparable s

236 2) employing mild redox reactions instead of harsh photochemical methods that decompose transiently f

237 S molecules modifying the SiNWs survived the harsh photolithographic processes, including coating wit

238 e transition to land exposed early plants to harsh physical conditions that resulted in key physiolog

239 ing process, microorganisms are subjected to harsh physicochemical conditions within the kilometer-de

240 The device is capable of functioning even in harsh physiological fluids, such as urine and bile juice

241 hese organometallic APNCs should not require harsh pretreatment for activation toward catalysis, such

242 s limited by the enzyme's sensitivity to the harsh process conditions.

243 insensitivity to both particle chemistry and harsh processing conditions.

244 ase-sensitive infectious prions destroyed by harsh proteolytic treatments.

245 ul mistakes, which are often associated with harsh punishment in abusive settings.

246 material with great potential for extremely harsh radiation environments.

247 inly with activated alcohols, which dictates harsh reaction conditions and thus limits its synthetic

248 diphenyl diisocyanate (4,4'-MDI) circumvents harsh reaction conditions and/or hazardous reagents empl

249 s are scarce and severely hampered by either harsh reaction conditions or the required use of stoichi

250 organic chemists, due to the involvement of harsh reaction conditions or the use of expensive cataly

251 ubstructures has been limited because of the harsh reaction conditions required to displace the chlor

252 considering that aldehydes normally require harsh reaction conditions to take part in such transform

253 g of the reaction mixture, and the effect of harsh reaction conditions were investigated.

254 oranes that would react with the traditional harsh reaction conditions, allowing the development of a

255 locks have commonly involved multiple steps, harsh reaction conditions, and the use of stoichiometric

256 thesize BT suffer from many drawbacks, e.g., harsh reaction conditions, multiple steps and poor selec

257 equire excess substrate or directing groups, harsh reaction conditions, weak or acidic C-H bonds, or

258 processes, however, have most often required harsh reaction conditions, which has drastically limited

259 N-(aminoalkyl)benzamides are few and employ harsh reaction conditions.

260 t steels for longer and safer life cycles in harsh reactor environments.

261 The fact that (harsh) reagents are used in excess in multiple reaction

262 ve reagents that require special handling or harsh reductants that limit functionality.

263 spect to performance and stability under the harsh regime of concentrated light.

264 does not use electricity, can be deployed in harsh/remote environments, and collects/preserves sample

265 oparticles, which are difficult to deploy in harsh reservoir conditions and where failures cause mate

266 he nanoparticle rapidly aggregated under the harsh seawater conditions.

267 ximately 30.000 s(-1), indicating that under harsh shear conditions FVIII is released from its carrie

268 roup on the precursor, which could withstand harsh SN2 reaction conditions with no side reactions.

269 However, the harsh sol-gel conditions and low thermal stabilities hav

270 ted in bacterial death due to other forms of harsh stress, we investigated the possible involvement o

271 current energy-intensive and environmentally harsh synthesis methods for materials.

272 The harsh synthetic conditions and associated limited struct

273 s largely eluded experimental study, because harsh synthetic methods are required to obtain them.

274 Harsh temperature and pH conditions enhanced the extract

275 e case in their mountainous stretches, where harsh terrain is seen as an impediment to travel.

276 protect brooding embryos from the chemically harsh, thermally fluctuating vent environment.

277 sh relevant m/z signals without the use of a harsh thresholding step, thus allowing for discovery of

278 mulitidendritic nociceptors that respond to harsh touch and cold temperatures.

279 hibits differential behavioural responses to harsh touch and gentle touch.

280 Whereas the harsh touch response depends solely on cell-autonomous m

281 ensory neurons and interneurons required for harsh touch sensation at different body segments.

282 characterizes the sensory channels mediating harsh touch sensation in C. elegans, establishing it as

283 Here we characterize harsh touch sensation in C. elegans.

284 However, little is known about harsh touch sensation in this organism.

285 dendritic nociceptors in the head respond to harsh touch throughout their receptive field but respond

286 orms lacking dma-1 were defective in sensing harsh touch.

287 t with this hypothesis, TasA fibers required harsh treatments (e.g., formic acid) to be depolymerized

288 he samples are often subjected to relatively harsh treatments that are unrealistic in a natural conte

289 Stressful conditions in the harsh tumor microenvironment induce autophagy in cancer

290 n the production of lipid biomass within the harsh tumor microenvironment.

291 ally regulate signaling pathways to adapt to harsh tumor microenvironments.

292 f the shift toward fast life histories under harsh, unpredictable conditions.

293 hat colder rather than warm climates are the harsh, unpredictable ones, thus requiring greater self-c

294 A harsh wash with 3% acetic acid eluted the strongly bound

295 ual schedules were severely disrupted by the harsh weather, with many individuals undertaking reverse

296 tive strategy that allows animals to survive harsh winter conditions.

297 talizations and protect public health during harsh winter conditions.

298 Stream conditions of low predation and harsh winters provide ecological justification for the s

299 rogen-protecting groups, excess reagents and harsh workup conditions.

300 the nest can buffer reproductive failure in harsh years.