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2 patient outcomes in several human cancers, no such advance has been achieved in muscle-invasive bladder cancer (MIBC).
3 Significant progress in meeting the need for FP has been achieved in Senegal, but more needs to be done parti
4 Doppler wire-derived coronary flow reserve has been applied in research studies, but its clinical role h
6 The 1,3-bielectrophilic reactivity of the MBH bromides has been demonstrated in the synthesis of 3,4-dihydro-2H-pyri
8 Increased expression of Interleukin (IL)-33 has been detected in intestinal samples of patients with ulce
9 Abusive treatment of women during childbirth has been documented in low-resource countries and is a deterr
10 A sugar-sweetened beverage (SSB) tax in Mexico has been effective in reducing consumption of SSBs, with larg
11 e exquisite dependency on CRAF kinase in KRAS mutant tumors has been established in genetically engineered mouse models a
14 nal attraction between a halogen atom and an electron donor has been exploited in knowledge-based drug design.
15 e analogue nucleoside reverse transcriptase inhibitor drugs has been identified in sub-Saharan Africa in patients with vi
17 The accumulation of dysfunctional mitochondria has been implicated in aging, but a deeper understanding of m
21 ge specification have been identified, and Notch signalling has been implicated in lineage allocation, but it remains unc
24 Essential for fetal testis descent, INSL3 has been implicated in testicular and sperm function in adult
25 Consequently, abnormal turnover of SGs has been implicated in the development of various pathologies
26 erner syndrome protein (WRN) is a RecQ family helicase that has been implicated in the efficient processing of G4 DNA str
29 rough cGMP has therapeutic potential in the colon, where it has been implicated in the suppression of colitis and colon c
30 cal mediators of any anti-viral immune response and IFNbeta has been implicated in the temporary control of lentiviral in
31 Vascular endothelial growth factor (VEGF)-A has been implicated in this context, but there are conflictin
32 Although the copper ion transporter CopA has been known in Escherichia coli, no gene for its chaperone
34 atures of this process remain obscure, significant progress has been made in recent years to decipher various molecular a
36 In recent years, significant progress has been made in the understanding of proteasome assembly, st
38 A dramatic increase in the incidence of IBD has been observed in the past 2 decades, mainly in developed
40 The quantum anomalous Hall (QAH) effect, which has been realized in magnetic topological insulators (TIs), i
43 32 that encodes a lncRNA, and the decreased MEG3 expression has been reported in multiple cancer tissues.
44 nd tailored management of patients with type 2 diabetes, as has been shown in patients with maturity onset diabetes of th
45 n by protecting the cohesin complex from cleavage, and this has been shown in yeasts to be mediated by recruitment of the
46 Endochondral ossification in the diaphysis of long bones has been studied in-depth during fetal development but not po
47 rate to reach a desired outcome is a difficult problem that has been studied in great detail using steady-state models.
48 morbidity and cost has led to a large body of research that has been summarised in systematic reviews and integrated into
49 under expanded access, the first time that an Ebola vaccine has been used in an outbreak setting outside a clinical trial
50 (MI-BCI) or transcranial direct current stimulation (tDCS) has been used in stroke rehabilitation, though their combinat
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