ライフサイエンスコーパス: have been elucidated

1 ing nor the molecular mechanism of switching had been elucidated.

2 pment and functioning of the auditory system have been elucidated.

3 ignaling in an androgen-depleted environment have been elucidated.

4 e TTF and newly formed triazole ring systems have been elucidated.

5 allene ether version of the Nazarov reaction have been elucidated.

6 lished specific genetic risk factors for CAD have been elucidated.

7 grees C, and details of the reaction pathway have been elucidated.

8 nor its link to the progression of apoptosis have been elucidated.

9 ts on TLR signaling of several of these SNPs have been elucidated.

10 the genesis of dyslipidemia and hypertension have been elucidated.

11 ction against primary sclerosing cholangitis have been elucidated.

12 hat directly control V(H) gene rearrangement have been elucidated.

13 eraction between parasite and mammalian host have been elucidated.

14 ructures of these in complex with chitinases have been elucidated.

15 inetic contributions to stability or folding have been elucidated.

16 nd the major biochemical mechanisms involved have been elucidated.

17 7, or either of these proteins with a kinase have been elucidated.

18 s and mechanisms of these signaling pathways have been elucidated.

19 ch intron and the intron/exon junctions also have been elucidated.

20 mitosene (2,7-DAM), the major MC metabolite, have been elucidated.

21 ecognition sites on AsiA and final sigma(70) have been elucidated.

22 half of them, binding sites on this collagen have been elucidated.

23 as zinc ligands and in binding and catalysis have been elucidated.

24 es of ulcerative colitis and Crohn's disease have been elucidated.

25 e structures that alter CD44 affinity for HA have been elucidated.

26 nt of DNA polymerase I from Escherichia coli have been elucidated.

27 tosol to trigger activation of NOD1 and NOD2 have been elucidated.

28 molecular mediators of tamoxifen resistance have been elucidated.

29 t to lie outside the reducing range of SmI2, have been elucidated.

30 local connectivity, and parallel processing have been elucidated.

31 of the relevant adaptive traits and variants have been elucidated.

32 lopathies that underlie cardiac arrhythmias, have been elucidated.

33 f drugs, discovered by phenotypic screening, have been elucidated.

34 nor the molecular mechanisms underlying them have been elucidated.

35 , and their underlying molecular mechanisms, have been elucidated.

36 athways that promote cell fate specification have been elucidated.

37 transplantation treatment for this disorder have been elucidated.

38 on efficiency and its transformation pathway have been elucidated.

39 g with the interaction of nkx2.7 with tbx20, have been elucidated.

40 mechanisms of NK activation postvaccination have been elucidated.

41 iated, and many of its underlying mechanisms have been elucidated.

42 SUMO elicits its effects on target proteins have been elucidated.

43 y which autophagy operates in these contexts have been elucidated.

44 systems, few of its developmental functions have been elucidated.

45 hways that lead to Th17 cell differentiation have been elucidated.

46 functional roles of key residues and motifs have been elucidated.

47 While multiple critical genes and pathways have been elucidated, a genome-wide analysis of gene exp

48 y have been known for some time, few details have been elucidated about changes that occur as a resul

49 monogenetic and complex polygenic disorders have been elucidated and functionally characterized.

50 of the biochemical steps of the PAO pathway have been elucidated and genes encoding many of the chlo

51 cribe characteristics of this chemistry that have been elucidated and how this chemistry may be utili

52 al abnormalities underlying these conditions have been elucidated and novel enzyme defects continue t

53 lecular contacts at the active site of FIH-1 have been elucidated and provide a platform for future d

54 The crystal structures of these receptors have been elucidated and reveal hydrogen bonding in the

55 ions of many previously uncharacterized COGs have been elucidated and tentative functional assignment

56 pathogenesis, the roles of several cytokines have been elucidated and tested in both preclinical anim

57 logy of pain transmission within the cranium have been elucidated, and advances been made into the pa

58 In the heart, elegant molecular pathways have been elucidated, and derangements in these pathways

59 defects underlying many of these conditions have been elucidated, and great progress has been made t

60 matory cascade underlying allergy and asthma have been elucidated, and IgE is now known to play a key

61 mical signaling pathways for these responses have been elucidated, and recent evidence points to the

62 he genetic bases for some of these disorders have been elucidated, and signaling pathways required fo

63 nteraction of these bacteria with their host have been elucidated, and the murine model of cystitis h

64 access, tumor biology, and cancer management have been elucidated as possible reasons for disparities

65 gh numerous direct neural targets of cocaine have been elucidated at the molecular level, little is k

66 (TF)-target gene binding relationships that have been elucidated at the molecular level.

67 several features of copper binding to LPMOs have been elucidated, but the identity of the reactive o

68 ric acid- and levamisole-sensitive receptors have been elucidated, but the levamisole-insensitive ace

69 matodes, globally acting regulatory pathways have been elucidated, but the more tissue- and organ-spe

70 plex formed by the oligonucleotide d(G3T4G3) have been elucidated by a combination of high-resolution

71 Sound British Columbia, and their structures have been elucidated by analysis of NMR and MS data.

72 The structures of the new dhilirolides have been elucidated by analysis of spectroscopic data a

73 les of function for light-gated ion channels have been elucidated by creating channelrhodopsins with

74 ly has a unique structure, features of which have been elucidated by DFT calculations.

75 ter partial chondroitin ABC lyase digestion, have been elucidated by disaccharide analysis, liquid se

76 The photophysics have been elucidated by intensity-dependent correlation

77 les from aqueous solutions of SnCl(4).5H(2)O have been elucidated by means of in situ X-ray total sca

78 ues have been obtained, and their structures have been elucidated by NMR spectroscopy and X-ray cryst

79 iamine-based Trost 'Standard Ligand' (R,R)-1 have been elucidated by NMR, isotopic labeling and compu

80 nal features of factor XIII and fibrin(ogen) have been elucidated by protein and gene analysis, site-

81 The functions of many cellular proteins have been elucidated by selective gene inactivation and

82 tion to increased levels of dietary peptides have been elucidated by studying the response to the sub

83 len)-catalyzed epoxidation by peracetic acid have been elucidated by the density functional [Becke th

84 rafficking and their roles in Cu homeostasis have been elucidated by the studies of model microorgani

85 acteristics of aromatic and aliphatic phases have been elucidated by the use of linear solvation ener

86 d truncated bacteriophage T4 gene 32 protein have been elucidated by two independent and sensitive me

87 l cycle regulation of Caulobacter crescentus have been elucidated by using defined unmethylated or he

88 solid-state structural features of 12 and 17 have been elucidated by X-ray crystallographic methods.

89 ), 3-Cp*, 3-(t)Bu, 4-Cp*, 4-(t)Bu, and 5-Cp* have been elucidated by X-ray crystallography.

90 opy, and the molecular structures of 6 and 8 have been elucidated by X-ray crystallography.

91 The structures of the porphyrins have been elucidated by x-ray diffraction analysis, and

92 al structures of the C-terminal domain of A1 have been elucidated, each in complex with a nanobody as

93 From this database there have been elucidated elements of recognition rules that

94 the structural biology of the Pap CU pathway have been elucidated, except for the C-terminal domain o

95 Important roles for autophagy have been elucidated for cell survival during nutrient i

96 s, as well as inventories of affected genes, have been elucidated for deletions of AZFa and of AZFc b

97 While many details have been elucidated for how the cytosol and endoplasmic

98 Although chemical mechanisms have been elucidated for many enzymes, the question of h

99 Contributions to O(2) activation have been elucidated for non-heme relative to heme ligan

100 the genetic factors predisposing to obesity have been elucidated for several rare syndromes, the fac

101 Two distinct mechanistic pathways have been elucidated for stoichiometric reactions of the

102 Only a few functionally significant residues have been elucidated for this enzyme, as well as for the

103 nection with details of the mechanism, which have been elucidated from kinetics, site-directed mutage

104 cellular determinants of heart regeneration have been elucidated, how injury triggers a regenerative

105 sms mediating genotoxic NF-kappaB activation have been elucidated, how this signalling is terminated

106 taxa inhabiting deep-sea hydrothermal vents have been elucidated; however, the physicochemical facto

107 growth and differentiation of the allantois had been elucidated in whole embryos.

108 ases in which the roles of individual miRNAs have been elucidated in behaving animals.

109 to conscious perception at a cortical level have been elucidated in both animals and humans.

110 e involved in atmospheric particle formation have been elucidated in controlled laboratory studies of

111 uction of cyclic strain into cellular events have been elucidated in cultured vascular cells.

112 tential (TRP) channels, particularly as they have been elucidated in heterologous expression systems.

113 In plants, cysteines have been elucidated in maintaining protein folding and

114 principles of chromatin remodelling as they have been elucidated in non-plant systems and to discuss

115 functions of such polyadenylated transcripts have been elucidated in only a few examples.

116 (IGF-1R) and estrogen receptors (ERs), which have been elucidated in other systems, have yet to be ex

117 of the budding yeast G1-S transition (Start) have been elucidated in recent years, especially with re

118 ed by bacterial and oomycete plant pathogens have been elucidated in recent years, information for th

119 cal excision of introns and joining of exons have been elucidated in recent years, the signaling path

120 , and dihydroxylated compounds, are degraded have been elucidated in recent years.

121 criptional level, and several major pathways have been elucidated in recent years.

122 s in asynchronous insect flight muscle (IFM) have been elucidated in situ using multiple approaches.

123 Although mechanisms of miRNA biogenesis have been elucidated in some detail, there is limited ap

124 These two hypotheses of genetic control have been elucidated in the literature.

125 of the TLR-mediated cell signaling pathways have been elucidated in the past few years, the molecula

126 ve been identified, and molecular mechanisms have been elucidated in yeast.

127 onic MPN phenotype to acute myeloid leukemia have been elucidated, including deletion of the transcri

128 derlying methicillin resistance in S. aureus have been elucidated, including regulatory events and th

129 The initial steps in DSB formation have been elucidated, involving cytosine deamination by

130 own, and the deregulated downstream pathways have been elucidated, it will be possible to identify vu

131 Although many of c-MYC's functions have been elucidated, its effect on the presentation of

132 lthough early stages of invadopodia assembly have been elucidated, little is known about maturation o

133 ral steps in MPO biosynthesis and processing have been elucidated, many questions remained, such as t

134 ereas the events responsible for its release have been elucidated, mechanisms regulating the nuclear

135 h the structures of many DNA binding domains have been elucidated, no detailed structures are yet ava

136 isms for iron entry and storage within cells have been elucidated, no system to mediate iron efflux h

137 ents of the hair-cell transduction apparatus have been elucidated only recently.

138 de of action of this virulence master switch have been elucidated, others remain unsolved.

139 As the complexities of dystrophic pathology have been elucidated over the last few years, it has bec

140 regarding the coevolution of bats and moths have been elucidated over the past 50 years.

141 sms for sensing mechanical and chemical cues have been elucidated over the past three decades, the me

142 hilic members of the family whose structures have been elucidated previously.

143 ction of inositol hexakisphosphate (InsP(6)) have been elucidated recently.

144 Furthermore, new details have been elucidated regarding the morphology and physio

145 perception, and signaling of these hormones have been elucidated, revealing the variety of mechanism

146 gh the general sortase-associated mechanisms have been elucidated, several structural attributes uniq

147 very few anthraquinone biosynthetic pathways have been elucidated so far, including the enzymatic dim

148 r which the structure-property relationships have been elucidated so far.

149 endent mechanisms of TF-induced angiogenesis have been elucidated that may signal through distinct pa

150 including innervation and taste acquisition, have been elucidated, the early patterning signals drivi

151 involved in synthesis of core and O-antigen have been elucidated, the effect of removing O-antigen a

152 ly steps in the biosynthesis of homoterpenes have been elucidated, the identity of the enzyme respons

153 ally induces catastrophic immune destruction have been elucidated, the important role that miRNAs pla

154 e for bacterial translocation into the heart have been elucidated, the initial interactions of heart-

155 Although CaMKIIalpha functions have been elucidated, the isoform-specific catalytic fun

156 oth open and closed states of the proteasome have been elucidated, the mechanism by which gates excha

157 he pathway regulating sexual differentiation have been elucidated, the mechanism of Sry action within

158 Although genetic and cell biological aspects have been elucidated, the molecular details of HP1 bindi

159 Although some embryological pathways have been elucidated, the molecular etiologies of ASD ar

160 onents of the class I MHC processing pathway have been elucidated, the participation of nonproteasoma

161 lization of individual germ plasm components have been elucidated, the process by which germ plasm as

162 g the generation of phenotypic heterogeneity have been elucidated, the speed with which identical sis

163 eterminants of this metabolic transformation have been elucidated, their broad biological implication

164 everal Hdacs in bone development and biology have been elucidated though in vitro and in vivo models.

165 and binding to MHC class II HLA-DR molecules have been elucidated through a combination of peptide st

166 Further clues to its regulation have been elucidated through biosynthetic pathway determ

167 etagogue stimulation of pancreatic secretion have been elucidated through characterization of the Src

168 a+/ myo-inositol cotransporter (SLC5A3) gene have been elucidated through cloning, sequencing, mRNA a

169 The growth processes have been elucidated through experiments that probe dire

170 The structure and function of ion channels have been elucidated through high-resolution x-ray struc

171 echanism and microstructure of the nanotubes have been elucidated through SEM, STEM, HAADF-STEM tomog

172 en the ring expansion reactions of 1b and 1c have been elucidated through the calculation of the ener

173 ated ubiquitination and degradation of HMGCR have been elucidated through the study of cultured mamma

174 endelian disorders, only about half of which have been elucidated to date.

175 f those plant and algal polysaccharides that have been elucidated to date.

176 ors that participate in patterning the heart have been elucidated (Tu and Chi, 2012), the cellular ev

177 been separated by HPLC, and their structures have been elucidated unambiguously by NMR spectroscopy,

178 nal disease, and although initiation factors have been elucidated, uncertainty concerning the downstr

179 Their electronic structures have been elucidated using a host of physical methods, i

180 redox oxidative C-O coupling, the mechanisms have been elucidated using density functional theory (DF

181 Structures of all the compounds have been elucidated using IR, NMR, MS, and elemental an

182 The structures of all of the compounds have been elucidated using IR, NMR, MS, and elemental an

183 chanisms of action of interventional devices have been elucidated using IVUS, and ultrasound is used

184 dy the genes regulated by MucR in B. abortus have been elucidated using microarray analysis and real-

185 tioselective oxidation of secondary alcohols have been elucidated using quantum mechanics (B3LYP DFT

186 ue lipid-protein interaction mechanisms that have been elucidated using SPR.

187 Key miRNA regulation features that have been elucidated via modelling include: (i) the role

188 some cases, the mechanisms of these effects have been elucidated, while other mechanistic functions

189 ation of 3-5 and their electronic structures have been elucidated with DFT calculations.

190 ry responsible for cellular self-destruction have been elucidated with unprecedented celerity during

191 cology of the soybean aphid in North America have been elucidated, with economic thresholds, sampling

192 ex and simple retroviruses and retroelements have been elucidated, with the exception of the gammaret

193 uctural biology of the peptidoglycan pathway have been elucidated, with the exception of the PNGM str

194 Many pathways regulating blood formation have been elucidated, yet how each coordinates with embr