ライフサイエンスコーパス: have led to

1 Anthropogenic activities have led to large-scale mercury (Hg) pollution in the Arctic.

2 Protein design advancements have led to biotechnological strategies based on more stable

3 Advances have led to an understanding of the importance of size (body

4 spectroscopy instrumentation and data processing algorithms have led to the emergence of Ramanomics - an independent disc

5 Findings emerging from epigenome-wide analyses have led to new discoveries with remarkable clinical applicat

6 sing over - make it an unusual component of the genome, and have led to its genetic variation becoming a key part of stud

7 n microscopy methods help to overcome these limitations and have led to new and refined insights into recombination mecha

8 ces have improved analysis of this complex modification and have led to the discovery of hundreds of ADP-ribosylated prot

9 ed light on the pathogenesis of different amyloid types and have led to identification of numerous new amyloid types, inc

10 o screen, isolate, and characterize HIV-specific antibodies have led to the identification of a new generation of potent

11 Advances in DNA sequencing and computational approaches have led to recent breakthroughs in the use of microbiome app

12 cent understandings in the development and spread of cancer have led to the realization of novel single cell analysis pla

13 The unique chemical and physical properties of CAP have led to its use in various biomedical applications includ

14 bacterial A-type CcOs, studies of bovine mitochondrial CcO have led to suggestions that its H channel instead provides t

15 new copies of the relevant gene to hematopoietic stem cells have led to safe and effective treatments for several PIDs, i

16 These concerns have led to critical revisiting and modification of prior pai

17 DL1 genes encoding C1 and C2 receptors, respectively, could have led to obsolescence of KIR2DP1(F) Alternatively, pathoge

18 ons requiring immediate intervention and that led (or could have led) to major disability or death.

19 studies toward the total synthesis of dehaloperophoramidine have led to the discovery of two novel domino processes, the

20 Decades of increasing vaccination and development have led to dramatic declines in the global burden of measles

21 Difficulties adhering to a gluten-free diet have led to the development of non-dietary therapies, several

22 The NIMH supported efforts have led to a vast increase in the amount of genetic and geno

23 development of new reactions based on C-H functionalization have led to its wider adoption across a range of research are

24 in neuroimaging, neuropathology, epidemiology, and genetics have led to a deeper understanding of how vascular disease af

25 onsiderable advances in the understanding of their genetics have led to increased clinical recognition of these condition

26 Concurrently, advances in tumor immunology have led to the development of immunomodulatory antibodies ta

27 rom the Chesapeake Bay, where anthropogenic nutrient inputs have led to eutrophication, hypoxia and anoxia, and low pH.

28 f the Mediterranean coast; and earlier soil moisture maxima have led to earlier winter floods in western Europe.

29 s can evolve rapidly and that natural genetic variation may have led to a SLO3 variant that differs from wild type in bot

30 Ecological-level studies suggest that MMLs have led to substitution of cannabis for opioids, and also po

31 Advances in bioinspired design principles and nanomaterials have led to tremendous progress in autonomously moving synthe

32 lecular and morphological characters, including nodulation, have led to major changes in our understanding of legume taxo

33 ons to the study of eusocial insect species, in particular, have led to several hypotheses for the processes underlying t

34 e (RTK)/Ras/mitogen-activated protein kinase (MAPK) pathway have led to clinical responses in lung and other cancers, but

35 These reports have led to the development of stereoretentive catalysts that

36 Concerns about acquisition of antibiotic resistance have led to increasing demand for new antimicrobial therapies

37 Advances in genome profiling and next-generation sequencing have led to the classification of HCCs based on molecular fea

38 icacy results from both in-vitro and in-vivo animal studies have led to their steady progression through clinical trials.

39 Although ancient-DNA studies have led to huge advances in our knowledge of these aspects o

40 ons account for 85-90% of GISTs; subsequent genetic studies have led to the identification of mutation/epimutation of add

41 The present studies have led to the identification of several structurally novel

42 erimental and theoretical studies of electrosensory systems have led to detailed accounts of how negative images are form

43 Since then, advances in genomic techniques have led to the identification of new monogenic disorders and

44 lecular biology and next generation sequencing technologies have led to the expenential growh of the sequence databases.

45 Warmer temperatures have led to earlier spring snowmelt floods throughout northea

46 ea, with three particular geological events hypothesised to have led to their isolation and divergence; (1) the opening o

47 Improvements in care and treatment have led to more young adults with life-limiting conditions l

48 ory of BT release and land use associated with urbanization have led to higher levels of BTs in urban areas and provide a

49 Europe; delayed winter storms associated with polar warming have led to later winter floods around the North Sea and some

50 pective with a focus on the key advances in knowledge which have led to the definition and exemplification of protein deg