ライフサイエンスコーパス: head-to-head

1 beta)(2), made up of alphabeta dimers linked head to head.

2 type locus contains a pair of genes arranged head-to-head.

3 sions where duplicated segments are arranged head-to-head.

4 RNA polymerase II (RNAPII) molecules collide head-to-head.

5 fector domains that interact with each other head-to-head.

6 re (5 Atkins, 4 WW, and 1 South Beach) and 2 head-to-head (1 of Atkins, WW, and Zone, and 1 of Atkins

7 ediates, i.e. 3- and 4-peptides that line up head to head across the entire APP transmembrane sequenc

8 We determined whether eligible studies were head-to-head active controlled trials and whether the re

9 ly motile cells that display no tendency for head-to-head agglutination and lack affinity to the ovid

10 Head-to-head analyses of relapse and disability outcomes

11 ructure reveals an unusual tetramer with two head to head and two tail to tail interactions, resultin

12 ollowing communication between sites in both head-to-head and head-to-tail orientations, we could sho

13 The nearly exclusive products from head-to-head and head-to-tail oriented "non-homologous"

14 bundant charged domain walls with conducting head-to-head and insulating tail-to-tail configurations,

15 lution at low micromolar concentrations, and head-to-head and side-to-side arrangements, respectively

16 Head-to-head and tail-to-tail magnetic domain walls in n

17 We performed head-to-head antigenic, immunogenic and molecular profil

18 e expression of a previously uncharacterized head-to-head antisense transcript, both transcripts bein

19 ted enhancement of gene expression involving head-to-head antisense transcription at a cancer-related

20 are located approximately 0.9 kb apart in a head-to-head arrangement in mammals.

21 A single crystal X-ray structure shows a head-to-head arrangement of porphyrins that explains bot

22 low gates in each hemichannel and the serial head-to-head arrangement of these gates in the intercell

23 The gene lies in a head-to-head arrangement with TFPT, a poorly characteriz

24 paired CSL-binding sites in a characteristic head-to-head arrangement.

25 in the Cph1 dimer are aligned in a parallel 'head-to-head' arrangement and that photoconversion betwe

26 that exhibit wild-type binding in univalent head-to-head assays are located in the interstrand regio

27 Head-to-head assembly of two spectrin heterodimers to fo

28 We performed a head to head assessment of FR104 (n=5), a selective pegy

29 he cytoplasms of two cells and are formed by head to head association of two hemichannels, one from e

30 by cisplatin have the HH1 conformation with head-to-head bases.

31 To test this hypothesis, we compared on a head-to-head basis the diagnostic performance of (64)Cu-

32 a larger prospective design, to compare on a head-to-head basis the performance of (64)Cu-DOTATATE an

33 and (68)Ga-DOTATOC PET/CT and compared on a head-to-head basis.

34 and (68)Ga-DOTATOC PET/CT and compared on a head-to-head basis.

35 in isoforms which suggests that heterotypic (head-to-head) binding between different claudin isoforms

36 Head-to-head biodistribution experiments comparing SA-bi

37 and healthy control subjects were evaluated head-to-head by the TST, QuantiFERON-TB-Gold in-tube tes

38 Head-to-head clinical trials are required to confirm the

39 CER methods in RA include head-to-head clinical trials, advanced techniques to sum

40 relative efficacy has not been determined in head-to-head clinical trials.

41 Thus, upon assembly of head-to-head CMGs that encircle double-stranded DNA at t

42 RNAPII stops but does not dissociate upon head-to-head collision in vitro, suggesting that opposin

43 Head-to-head collision in vivo also results in RNAPII st

44 This study provides the first head-to-head comparative analysis of leading antigens us

45 This controlled clinical head-to-head comparative study revealed PET to exhibit t

46 As head-to-head comparative trials between P2Y12-receptor a

47 We head-to-head compared the accuracy of these systems in p

48 In a head to head comparison on loops extracted from freshly

49 In our head to head comparison, SMART and CLARK had similar acc

50 In head-to-head comparison (using satellite data from 2003

51 This head-to-head comparison aimed to identify genes required

52 Head-to-head comparison and validation of these tracer c

53 This was a head-to-head comparison between (68)Ga-labeled prostate-

54 Head-to-head comparison between ferret and human antiser

55 ools, Kattan nomogram and CAPRA-S score in a head-to-head comparison for predicting risk of recurrenc

56 PGE2 are more competitive, as determined by head-to-head comparison in a competitive transplantation

57 Head-to-head comparison in human lung cells by NGS revea

58 wo clinical trials have been published and a head-to-head comparison is lacking to date.

59 Here, a head-to-head comparison is made between mechanisms based

60 etection of TF, we performed a prospective a head-to-head comparison of (18)F-FDG and (18)F-FLT in pa

61 The goal of this study was to make a head-to-head comparison of 2 common forms of multidiscip

62 igate some of the challenges revealed in our head-to-head comparison of aptamer binding assays, we fu

63 e goal of this study was to conduct a direct head-to-head comparison of different stem cell types in

64 Head-to-head comparison of fibrosis biomarkers ST2 and G

65 We performed a head-to-head comparison of five different adjuvants Alum

66 logous primary myeloid target cell types for head-to-head comparison of infection rates, viral output

67 Interestingly, a head-to-head comparison of mice with deletion of Adora2b

68 This head-to-head comparison of prasugrel and ticagrelor does

69 INTERPRETATION: This first head-to-head comparison of quetiapine-ER versus aripipra

70 This first head-to-head comparison of recombinant versus inactivate

71 Based on these results, a head-to-head comparison of rivaroxaban with long-term lo

72 fore, this study was undertaken as the first head-to-head comparison of subcutaneous (SC) abatacept a

73 No randomized head-to-head comparison of the efficacy and safety of ti

74 is of the parent N-H BN indole and provide a head-to-head comparison of the structural features, pK(a

75 No head-to-head comparison of these regimens has been condu

76 The present study is a large, randomized head-to-head comparison of these treatments on outcomes

77 The phase 3 ENDEAVOR trial was a head-to-head comparison of two proteasome inhibitors in

78 Head-to-head comparison showed that (89)Zr-transferrin t

79 The head-to-head comparison study of Snake and Taqman reveal

80 A blind, head-to-head comparison study of SpinDx versus the gold-

81 rtussis detection, although there is limited head-to-head comparison to evaluating the PCR yield from

82 ative of the tumor as a whole as assessed by head-to-head comparison to single cell suspensions of di

83 A head-to-head comparison was performed of the effects of

84 The procedures developed for this head-to-head comparison will be useful for future evalua

85 pients over a period of 42 d and performed a head-to-head comparison with a conventional B cell ELISp

86 attractive new vaccine candidate that merits head-to-head comparison with other modalities of vaccine

87 egression analysis was used, combined with a head-to-head comparison, for follow-up at 12, 24, and 60

88 In a head-to-head comparison, however, the B. burgdorferi Del

89 Strikingly, in a head-to-head comparison, oncogenic BRAF(V600E) elicited

90 Through a head-to-head comparison, we find that ICE libraries yiel

91 ickening with, however, scarce data on their head-to-head comparison.

92 luoroethyl)tyrosine ([(18)F]FET) tracer in a head-to-head comparison.

93 Differences in trial design and lack of head to head comparisons to date make it difficult to de

94 Though there are no head to head comparisons with other pharmacological agen

95 In head-to-head comparisons among children with both GA and

96 Head-to-head comparisons among NOACs were not available.

97 However, no head-to-head comparisons between MRE and ARFI for diagno

98 cs are the best options in HE treatment, but head-to-head comparisons between these drugs are scarce.

99 Head-to-head comparisons between various medications and

100 Because head-to-head comparisons of AEDs (used in the European U

101 Head-to-head comparisons of conventional influenza vacci

102 This work carries out head-to-head comparisons of currently available NIR-II p

103 n to inactivate platelet COX-1 will confound head-to-head comparisons of distinct NSAIDs in ongoing c

104 gies during transitions in care) rather than head-to-head comparisons of medications.

105 d 140 trials and 26 observational studies of head-to-head comparisons of monotherapy or combination t

106 There were no head-to-head comparisons of NOACs and limited data on ha

107 long-term follow-up data are available from head-to-head comparisons of second-generation drug-eluti

108 Despite the rather limited number of head-to-head comparisons of sstr antagonists and agonist

109 We performed head-to-head comparisons of the cellular and humoral imm

110 We tested this assumption by performing head-to-head comparisons of the requirements for each co

111 upranational reference laboratories to allow head-to-head comparisons of two new tests, Hain Genotype

112 Head-to-head comparisons were sparse, and network meta-a

113 All the head-to-head comparisons were supported by very-low-qual

114 Future studies and head-to-head comparisons with conventional ablation tech

115 In head-to-head comparisons with the relevance-chain, multi

116 Head-to-head comparisons with the relevance-chain, multi

117 placebo-controlled studies predominate over head-to-head comparisons, although the latter would be m

118 Few trials, no head-to-head comparisons, and inadequate follow-up in ma

119 Sensitivity and specificity estimates, head-to-head comparisons, measures of agreement, and lat

120 trial results to real-world settings include head-to-head comparisons, some that incorporate noninfer

121 ed with previously validated methods through head-to-head comparisons.

122 nd outcome measurement were heterogenous for head-to-head comparisons.

123 ect evidence available from randomized blind head-to-head comparisons.

124 ety data, possible publication bias, and few head-to-head comparisons.

125 ensional cell culture has yet to be shown in head-to-head-comparisons.

126 and wild-type (WT) virus were competed in a head-to-head competition assay to determine how differen

127 Head-to-head competition assays on agar plates indicate

128 ss differences were identified using ex vivo head-to-head competition assays.

129 The contest will entail a head-to-head competition starting on 3 January 2013.

130 First, by direct head-to-head competition, nuclear-localized SerRS blocks

131 ids and outcompeting the wild-type genome in head-to-head competition.

132 by directly measuring allelic frequencies in head-to-head competitions using a mass spectrometry-base

133 nt dimerization and that UL9 dimers are in a head-to-head configuration.

134 Convergent gene pairs with head-to-head configurations are widespread in both eukar

135 ge two-helical assemblies that associate via head-to-head contacts between coiled-coil middle domains

136 the majority of molecules are dimeric with a head-to-head contour distance of approximately 50 nm.

137 The evidence favored head-to-head coupling yielding ligated diboranes.

138 e furan backbone is almost unaffected by the head-to-head defect which is known to cause considerable

139 d in multiple orientations (head-to-tail and head-to-head), depending on the specific DNA contacts.

140 Both kinases reveal a head to head dimer with one major dimeric interface thro

141 gen-binding sites of these antibodies form a head-to-head dimer and cooperatively recognize the antig

142 ike human cytomegalovirus UL44, PF-8 forms a head-to-head dimer in the form of a C clamp, with its co

143 The PhyB PSM crystallized as a head-to-head dimer with strong structural homology to it

144 ture of piperarborenine D is reassigned to a head-to-head dimer, which was synthesized using an intra

145 lel beta-helix, antiparallel beta-helix, and head-to-head dimer.

146 In the structure, RctB adopts a head-to-head dimeric configuration that likely reflects

147 c molecular dynamics simulation study of AmB head-to-head dimerization in a phospholipid bilayer, a p

148 The His61Tyr mutation on loop 5 weakens head-to-head dimerization, yet a side-to-side dimer bind

149 In particular, "head-to-head" dimerization occurs when the intrinsically

150 The head-to-head dimers have two lateral loops on the same G

151 In the head-to-head dimers that form the conducting, membrane-s

152 ahorse-shaped zinc-aminopeptidase that forms head-to-head dimers.

153 Only a head-to-head direct comparison of the different new OACs

154 erent treatments, but in the absence of such head-to-head direct comparisons, another alternative to

155 Random effects meta-analyses summarised head-to-head (direct) comparisons, and network meta-anal

156 A "head-to-head" direct comparison of drugs is the standard

157 he discrepancy is the occurrence of spectrin head-to-head disassociation which is also included withi

158 The HelitronFinder program identified two head-to-head dissimilar Helitrons in a maize BAC sequenc

159 ferroelectric BaTiO3 tunnel barrier, where a head-to-head domain wall is constrained.

160 ias that leads to energetically unfavourable head-to-head domain walls in as-grown epitaxial PbZr(0.2

161 ins of replication are selected by loading a head-to-head double hexamer of the Mcm2-7 replicative he

162 two heterohexameric Mcm2-7 complexes into a head-to-head double hexamer that facilitates bidirection

163 Minichromosome Maintenance (MCM) proteins as head-to-head double hexamers during DNA replication orig

164 ve helicase encircles double-stranded DNA as head-to-head double hexamers.

165 romyces cerevisiae and other eukaryotes as a head-to-head double-hexamer around origin DNA.

166 In head-to-head experiments with PAC-1, pharmacokinetic eva

167 an asymmetric tunnel-fold homodecamer of two head-to-head facing pentameric subunits, harboring 10 ac

168 roximately 10%) are arranged in a divergent, head-to-head fashion and controlled by bidirectional pro

169 Linking inactive, monomeric proteins in a head-to-head fashion by an intermolecular disulfide bond

170 study compared these approaches in a direct head-to-head fashion in a contemporary population.

171 metrically to opposite faces of the DNA in a head-to-head fashion with a loophelix motif making seque

172 occupied by Hsp47 molecules, which bind in a head-to-head fashion, thus making extensive contacts wit

173 llizes as a C3-symmetric dimer in an unusual head-to-head fashion.

174 nhibitors (ARNI), have not been studied in a head-to-head fashion.

175 AlO3 on SrTiO3 substrate is accompanied with head-to-head ferroelectric-like polarizations across the

176 II was organized into laterally associated, head-to-head filament chains highly reminiscent of mamma

177 te by measurements in which two RNAs compete head-to-head for a limited amount of CP.

178 We compared MRE versus ARFI head-to-head for diagnosing fibrosis in well-characteriz

179 ST2 and galectin-3 (Gal-3) were compared head-to-head for long-term risk stratification in an amb

180 Half are between head-to-head gene pairs.

181 Head-to-head genes have, on average, lower gene expressi

182 as a cis regulatory element separating close head-to-head genes with different transcription regulati

183 osaccharides are symmetrically joined, by a "head-to-head" glycosidic linkage between their carbonyl

184 perature in the absence of added salt and as head-to-head hairpin dimers in the presence of >50 mM Na

185 A distribution of head-to-head, head-to-tail, and tail-to-tail regiochemis

186 Idas in complex with Geminin showed a tight head-to-head heterodimeric coiled-coil.

187 tion complex, including the formation of two head-to-head hexameric helicases around the replication

188 Note that head-to-head (HH) linkages have traditionally been avoid

189 itate the conversion of coumarin to its anti-head-to-head (HH) photodimer with high selectivity.

190 Compared head to head, high-dose aprotinin demonstrated significa

191 he glycine-rich tail is sufficient to form a head-to-head homodimer primarily via its N-terminal doma

192 Head-to-head hybridization of these transcripts blocks s

193 pairs, the AG and Watson-Crick pairs are all head-to-head imino-paired (cis Watson-Crick/Watson-Crick

194 inary validation, but few have been compared head to head in independent centers and in different sta

195 In head-to-head infections at fixed multiplicities of infec

196 haI-spectrin fragment containing the site of head-to-head interaction with the beta-chain binds more

197 Our data are most consistent with head-to-head interactions in a 2:2:1 XRCC4:XLF:Ligase IV

198 ate formation of the rod-shaped tetramer via head-to-head interactions of two APO2 dimers.

199 Moreover, we show that the head-to-head juxtaposition of the Mcm2-7 double hexamer

200 dgap (1.37-1.46 eV) polymers incorporating a head-to-head linkage containing 3-alkoxy-3'-alkyl-2,2'-b

201 The head-to-head linkage enables polymers with sufficient so

202 LOH), by conditionally inactivating Ext1 via head-to-head loxP sites and temporally controlled Cre-re

203 osed of four exons and it is orientated in a head-to-head manner to IRXA2.

204 atively and result in association of stable, head-to-head Mcm2-7 double hexamers connected via their

205 A head-to-head molecular assembly configuration of the NGF

206 We propose that head-to-head motors may generate energy that underlies i

207 tegy was a 1 year, double-blind, phase 3b/4, head-to-head, non-inferiority, randomised controlled tri

208 The head-to-head NS1(172-352) dimer we observe in crystal la

209 c acid, and tranexamic acid with placebo and head to head on 8 clinical outcomes from 138 trials.

210 nt differences among any agent when compared head to head on other outcomes.

211 otopic subcomponents, respectively, allows a head-to-head or head-to-tail double helix to be generate

212 s and transcribing RNA polymerases in either head-to-head or head-to-tail orientations, as well as Ec

213 ized that upstream distance and orientation (head-to-head or head-to-tail) are important for the prom

214 The effect of target site orientation (head-to-head or head-to-tail) on the TPM behavior of syn

215 cent genes organized in a divergent fashion (head to head orientation) and separated by <1 kb.

216 t of Stx2e, one NbStx2e1 is interacting in a head-to-head orientation and directly competing with the

217 tal structure shows that 2 PapC molecules in head-to-head orientation interact via exposed beta-stran

218 human CYP1A genes CYP1A1 and CYP1A2 are in a head-to-head orientation on chromosome 15.

219 Closely apposed genes in a head-to-head orientation share the same upstream region

220 curs via rigid body docking of monomers in a head-to-head orientation to form kinetically trapped dim

221 When the sites are in head-to-head orientation, the knot products contain even

222 mbinogenic locus with PfRh2a and PfRh2b in a head-to-head orientation.

223 two Mcm2-7 helicases around origin DNA in a head-to-head orientation.

224 thylated DNA sequences in inversely repeated head-to-head orientations for efficient cleavage to occu

225 s harboring this intergenic sequence between head-to-head oriented green fluorescent protein and beta

226 cotranscribed with their parents and 3% with head-to-head oriented neighbors.

227 , we noted that AtClpB-C and AtCK2 genes are head-to-head oriented on chromosome 1 of the Arabidopsis

228 nt, random sites were only observed when two head-to-head oriented, unmethylated copies of the site w

229 The divergent depolarization fields of the head-to-head polarizations cast the interface into an el

230 lues for the mechanism and inhibition of the head-to-head prenyl transferases and should aid future d

231 phosphates from C(5) precursors; the epsilon head-to-head prenyl transferases that convert these diph

232 These protein kinases bind "head-to-head," present their respective active sites on

233 sis of a symmetrical monomer that provides a head-to-head pyridine building block for the preparation

234 The FIM12 study was a head-to-head randomised controlled trial in which 31,989

235 A lack of head-to-head randomized clinical trials (RCTs) comparing

236 The lack of head-to-head randomized controlled trials makes choosing

237 There are limited head-to-head randomized data on patient-related versus s

238 The first head-to-head randomized phase III comparative study betw

239 lure is thought to be a class effect, but no head-to-head randomized trials have compared individual

240 arison (MTC) meta-analysis uses both direct (head-to-head) randomized clinical trial (RCT) evidence a

241 When the architecture of this pair of head-to-head RBPjkappa binding sites is changed, the sit

242 However, the 2 head-to-head RCTs suggest that Atkins (range: -2.1 to -4

243 Head-to-head RCTs, providing the most robust evidence av

244 cloadditions proceed to give head-to-tail or head-to-head regioisomers, depending on the nature of th

245 vage of two recognition sites in an inverted head-to-head repeat.

246 between a pair of target sites in inverted (head-to-head) repeat.

247 inherent long-term competitiveness in a HSC head-to-head secondary transplantation model.

248 Spermatozoa agglutinated head-to-head show contact-induced coalescence of GM1 gan

249 the highest abundance of the single stranded head to head (SSHH) conformer.

250 allel double helix (PDH) and single-stranded head-to-head (SSHH) dimers were observed.

251 ymmetric unit, two associating together as a head-to-head stacked dimer, and the third as a single he

252 This was supported by meta-analysis of head-to-head studies (odds ratio, 9.617 [2.654-34.845])

253 However, to date, prospective head-to-head studies are lacking regarding the diagnosti

254 However, head-to-head studies are needed to assess the relative e

255 s daily dose of 12.5 to 25 mg as measured in head-to-head studies by ambulatory BP measurement is con

256 bviously, the ideal way to do this is to use head-to-head studies in CSU.

257 ences in diagnostic accuracy (moderate SOE); head-to-head studies of other biomarkers were limited.

258 Comparative evidence is limited by few head-to-head studies.

259 The results are similar to those of previous head-to-head studies.

260 Based on statistical decision theory, our head-to-head study suggests that QuantiFERON-TB Gold In-

261 For this randomised, open-label, phase 3 head-to-head study, we enrolled patients (from centres i

262 If at least one 'head-to-head' study was found then a mixed treatment com

263 estigator blind thereafter), parallel-group, head-to-head superiority study (EXXELERATE), eligible pa

264 structure of ZIKV NS1172-352, which forms a head-to-head, symmetric dimer with a unique 14-stranded

265 lf-assembles into a bilayered structure with head-to-head, tail-to-tail arrangements of each particle

266 ric intermediates; loci 1, 2, and 5 produced head-to-head/tail-to-tail concatemers; and locus 7 yield

267 "Head-to-head" terpene synthases catalyze the first commi

268 We show that two monomers directly contact head-to-head through the FAT and kinase domains.

269 med DUOX maturation factor (DUOXA2) arranged head-to-head to and co-expressed with DUOX2.

270 tiple immunogens and immunization strategies head-to-head to determine their impact on the quantity,

271 Their anti-parallel head-to-head-to-tail 'triplex' strand arrangement create

272 Only 1 head-to-head trial met the inclusion criteria; both this

273 Seven placebo-controlled RCTs and 1 head-to-head trial provide results for main outcomes.

274 In a head-to-head trial, we compared the safety and efficacy

275 en an area of speculation with no definitive head-to-head trial.

276 stic accuracy has not been compared in large head to head trials.

277 In head-to-head trials (4 RCTs), no difference in the likel

278 Head-to-head trials (n = 23), mostly examining synthetic

279 Two persons independently selected relevant head-to-head trials and prospective cohort studies with

280 s new members of a drug class are developed, head-to-head trials are an important strategy to guide p

281 Because additional head-to-head trials are unlikely, any further investigat

282 agents are effective treatments for UC, but head-to-head trials are warranted to establish the best

283 Although no head-to-head trials compare HCTZ with the uncommonly pre

284 To date, head-to-head trials comparing the efficacy and safety of

285 py the European Medicines Agency will accept head-to-head trials designed to show noninferiority for

286 Large head-to-head trials evaluating long-term treatments are

287 We performed a systematic search of head-to-head trials for gaining objective reliable data

288 Head-to-head trials have shown CTDN's superiority in ant

289 with industry-sponsored trials, the lack of head-to-head trials of new effective treatments, the nee

290 Also, essential head-to-head trials of therapies for this complex progre

291 Until head-to-head trials or large-scale observational studies

292 Nine head-to-head trials showed greater pain reduction associ

293 earch was updated to August 2007 to identify head-to-head trials that reported blood pressure outcome

294 Head-to-head trials to guide antipsychotic treatment cho

295 venous sinus stenting should be compared in head-to-head trials with optic nerve sheath fenestration

296 placebo, to undertake a systematic review of head-to-head trials, and to compare the relative effecti

297 e of the entire photosensing module showed a head-to-head, twisted dimeric arrangement with bowed hel

298 800), a fully automated system, was compared head to head, using female samples, to Gen-Probe Aptima

299 ivatives between two reporter genes oriented head to head, we show that the TAL effector drives expre

300 s efficacy and safety have not been compared head-to-head with the next-generation everolimus-eluting