ライフサイエンスコーパス: heal

1 ng by secondary intention, which was slow to heal.

2 lving and nonresolving pathway in myocardial healing.

3 vant to cancer, vascular diseases, and wound healing.

4 eria can colonize the wound and impair wound healing.

5 ) accelerates the process of acid burn wound-healing.

6 ) to determine the function of MLL1 in wound healing.

7 rs and conditions can lead to impaired wound healing.

8 pathogen defense, organ rejection, and wound healing.

9 ot interfere with skin development and wound healing.

10 duced FPD development by promoting FPD wound healing.

11 volved in developmental regulation and wound healing.

12 obiota over time and their associations with healing.

13 the fracture callus and for undisturbed bone healing.

14 organized collagen formation and poor tissue healing.

15 (TM) play a role in skin integrity and wound healing.

16 d angiogenesis, especially in diabetic wound healing.

17 ic bone were associated with impaired socket healing.

18 t are likely associated with improved tendon healing.

19 vement of keratinocytes in connective tissue healing.

20 for osteoarthritis (OA) and diminished wound healing.

21 ying regenerative vs non-regenerative tendon healing.

22 tical bone, as well as asymmetry in fracture healing.

23 regeneration, resulting in delayed fracture healing.

24 ayed repair, and TIP39 treatment accelerated healing.

25 olonged inflammatory phenotype in late wound healing.

26 2 polarization of macrophages in acute wound healing.

27 vs patients with asymptomatic IBD in mucosal healing.

28 rogressive fashion promotes pathologic wound healing.

29 vo for their ability to promote dermal wound healing.

30 AK, ASK1, and PP5 in ATII cells during wound healing.

31 the beneficial effects of PTH2R signaling on healing.

32 uired altered cutaneous bacteria and delayed healing.

33 d to altered long bone properties and callus healing.

34 arginine uptake mediates AS II-induced wound healing.

35 2 ulcer pathogenesis, severity, or prolonged healing.

36 icacy of platelet-derived proteins for wound healing.

37 hown to promote the corneal epithelial wound healing.

38 related miRNAs with potential roles in wound healing.

39 cx in cortical bone development and fracture healing.

40 during papilloma induction and during wound healing.

41 nd deficiencies in the MMP9 lead to impaired healing.

42 macrophages and play central roles in wound healing.

43 aspect of re-epithelialization during wound healing.

44 e potential to induce angiogenesis and wound healing.

45 lating cellular traits associated with wound healing.

46 nderstood inputs for organogenesis and wound healing.

47 uld promote fast and scarless gingival wound healing.

48 s of chronic inflammation, cancer, and wound healing.

49 nt in 16.3% of patients with IBD and mucosal healing (15.4% of patients with CD, 17.4% with UC).

50 hness, damping, fatigue resistance, and self-healing ability is required.

51 top and bottom molecules, revealing the self-healing ability of the beta roll stack.

52 estal, or subcrestal (-1.5 mm) position, and healing abutments were connected.

53 a concentration-dependent incidence of wound healing adverse events (WHAE).

54 -links to reassemble, the hydrogels can self-heal after being strained to failure, in most cases reco

55 ssue for 10 weeks, while control groups were healed after 4 weeks.

56 production is essential for intestinal wound healing after colonic surgery, possibly via its effects

57 Perineal wound healing after eAPR with preoperative radiotherapy for re

58 est that 3S may be used to safely accelerate healing after injury in diverse clinical contexts.

59 sor is an effective tool to help assess bone healing after internal fixation and could provide an obj

60 or T cells in profibrotic cardiac repair and healing after ischemia, little is known about whether T

61 Thus, the PGE2/Ep3 axis promotes cardiac healing after MI by activating reparative Ly6C(low) Mos/

62 Ep3 deletion in Mos/Mps markedly attenuates healing after MI by reducing neovascularization in peri-

63 nic conductor is presented that autonomously heals after experiencing severe mechanical damage.

64 ns, overcoming limitations faced by previous healing agents such as chitosan agglomerates.

65 in situ healing of compromised membranes via healing agents that are added to the feed side of a memb

66 pha3beta1 promotes this process during wound healing, alpha9beta1 has an inhibitory role, suggesting

67 for understanding why some fractures fail to heal and for developing novel therapeutic interventions.

68 organisms and tissues display the ability to heal and regenerate as needed for normal physiology and

69 In 6 weeks, the chorioretinal lesions had healed and visual acuity had improved to 20/25 OD and 20

70 ly incorporate treatment to accelerate ulcer healing and address MRSA into the care of diabetic patie

71 t the 10-lipid mixture, because of its wound-healing and antimicrobial properties, can be beneficial

72 cx-mutant mice demonstrated disrupted callus healing and asymmetry.

73 iation, and migration and in epidermal wound healing and barrier repair.

74 d cell behaviors to those activated in wound healing and identifies a repertoire of potential targets

75 tical tools with in vivo models of osteotomy healing and implant osseointegration to determine if one

76 unity instability was associated with faster healing and improved outcomes.

77 mation of organs, tissue regeneration, wound healing and many disease processes, including cancer.

78 ed exosomes may be involved in corneal wound healing and neovascularization, and thus, may serve as t

79 proteins involved in defense response, wound healing and protein phosphorylation when compared to nor

80 ived, transplanted ASCs can accelerate wound-healing and reduce hair loss in acid-burn skin injury.

81 view presents current understanding in wound healing and regeneration as two distinct aspects of cell

82 signaling on alveolar epithelial cell wound healing and repair, as well as on expression of elastoge

83 ns, while in adult tissues they aid in wound healing and the maintenance of intestinal cell populatio

84 reaction network, they are autonomously self-healing and they are highly adaptive to small changes in

85 levate in vivo levels of PGE2 and to promote healing and tissue regeneration.

86 al WNT-driven alveolar epithelial cell wound healing and transdifferentiation in vitro.

87 ties to prevent infection of burn wound, aid healing, and an anti-inflammatory dressing material.

88 act allergic and autoimmune responses, wound healing, and anti-microbial defense.

89 ganization in biofilms, embryogenesis, wound healing, and cancer metastasis.

90 tion and is involved in tissue repair, wound healing, and clearance of apoptotic cells and cellular d

91 shown to favor embryonic development, wound healing, and even tumor growth, suggesting more complex

92 ited positive correlations with OA, impaired healing, and inflammatory adipokines.

93 Selective inhibition of cell adhesion, wound healing, and invasion are demonstrated; near-infrared fl

94 critical for embryonic development and wound healing, and occurs in fibrotic disease and carcinoma.

95 cularization are to relieve pain, help wound healing, and prevent limb loss.

96 ation of cells in stem cell therapies, wound healing, and the treatment of cancer.

97 The wound healing assay reveals that inhibiting either BCL2L11 or

98 ntestinal cancer cell line Caco-2 in a wound-healing assay, and in mice colon wounds.

99 All cell migration and wound healing assays are based on the inherent ability of adhe

100 Furthermore, cell invasion and wound healing assays together with qRT-PCR determination of ep

101 and promotes healing by using in vitro wound healing assays, human ex vivo and porcine in vivo wound

102 Moreover, the elastomer can self-heal at room temperature with a recovered tensile streng

103 study aimed to compare the difference in GU healing between H. pylori-infected patients with IM and

104 n the dense fibrin matrix and can be used as healing biomaterial.

105 monstrated that FOXO1 was activated in wound healing but to higher levels in diabetic wounds.

106 Most surgical wounds heal by primary intention, that is to say, the edges of

107 ion-free survival by 18%, and improved wound healing by 59%, without affecting mortality.

108 in mice with colitis and accelerates mucosal healing by activating STAT1.

109 glucocorticoid (GC) downregulation of wound healing by interaction with the membrane bound GC recept

110 g mediators of inflammation accelerate wound healing by preventing chronic inflammation and allowing

111 sue loss), and are known as 'surgical wounds healing by secondary intention'.

112 or older and had at least one surgical wound healing by secondary intention, which was slow to heal.

113 particularly to "unexpected" surgical wounds healing by secondary intention.

114 vastatin reverses FPP's effects and promotes healing by using in vitro wound healing assays, human ex

115 cxGFP(+) cells were localized throughout the healing callus after fracture.

116 polymer networks, exhibiting remarkable self-healing capability at room temperature.

117 test the method, we compared well and poorly healing cardiac ventricles using a transgenic fish model

118 During skin wound healing, CD26-positive cells accumulated over time and p

119 The primary endpoint was mucosal healing (CDEIS <4) with absence of deep ulcers 48 weeks

120 Wound healing complications were more prevalent in the bevaciz

121 nanoparticles also have the ability to self-heal defects in their crystal structures.

122 was the rate of uncomplicated perineal wound healing defined as a Southampton wound score of less tha

123 ts, and while regenerative dentistry aims to heal dental tissue after injury, existing polymeric rest

124 g the proliferative phase of cutaneous wound healing, dermal fibroblasts are recruited into the clott

125 y a key role in tissue homeostasis and wound healing during Th2-mediated immune responses, such as pa

126 Meanwhile, nanopores shrink (self-heal) during radiation, and their shrinkage rate is pore

127 Although the wound healing effects of nitric oxide (NO) are known, the mech

128 tensile loads, and exhibit a remarkable self-healing efficiency.

129 integration to determine if one type of bone healed faster and supported osseointegration better than

130 demonstrated clearance of bacteria and wound healing following repeated i.v. administration of activa

131 emarkably, LCMV coinfection of mice that had healed from L. guyanensis infection induced reactivation

132 i1+ cells and hedgehog signaling in enthesis healing, Gli1 expression was examined via lineage tracin

133 However, the role of Scx in fracture healing has not yet been explored.

134 utoff, 36.2% of patients with IBD in mucosal healing have increased intestinal permeability.

135 and myofibroblast formation in corneal wound healing have not been fully elucidated.

136 A transparent, self-healing, highly stretchable ionic conductor is presented

137 cal processes including embryogenesis, wound healing, host immunity, and tumor suppression.

138 imulation (ES) is known to promote cutaneous healing; however, its ability to regulate reinnervation

139 However, some wounds may be left open to heal (if there is a risk of infection, or if there has b

140 al Gli1+ cell population had the capacity to heal immature entheses after injury, but this capacity w

141 as a central clinical issue for RDEB, wound healing impairment has been only marginally investigated

142 wever, implanted materials can cause further healing impairments due to the persistent inflammatory s

143 s and mechanism of AS II on intestinal wound healing in both in vitro and in vivo models.

144 eneficial in the treatment of impaired wound healing in diabetes.

145 ensin system is implicated in abnormal wound healing in diabetic and older adults.

146 er significantly accelerated cutaneous wound healing in diabetic mice through facilitating angiogenes

147 ting antiretroviral effects on genital wound healing in future clinical trials.

148 e, using an in vivo model of cutaneous wound healing in mice, we provide evidence that GPNMB is funct

149 cyte cell line and demonstrated potent wound healing in mice.

150 n of epidermal caspase-8 as a model of wound healing in Mus musculus, we analyzed the signaling compo

151 udin, down-regulation had no impact on wound healing in normal scratch assays, but after subjecting t

152 Compared to skin, wound healing in oral mucosa is faster and produces less scarr

153 method can be readily applied to image wound healing in other injured or diseased tissues, or to moni

154 We concluded that corneal endothelial wound healing in rabbits has different outcomes depending upon

155 cells (ATII) are instrumental in early wound healing in response to lung injury, restoring epithelial

156 erexpression significantly accelerated wound healing in STZ-induced diabetic mice.

157 ximately 2 to 4 weeks and better periodontal healing in terms of conventional flap sites.

158 a dampening of the host immune response and healing in the mouse model, and it may provide an altern

159 -acetylcysteine accelerates amputation stump healing in the setting of diabetes.

160 rates, mitotic activity, and osteotomy site healing in type III bone and high endogenous Wnt signali

161 sa was sufficient to impair epithelial wound healing in vivo.

162 gh distinct, yet overlapping phases of wound healing, including hemostasis, inflammation, proliferati

163 as assessment of wound healing using a wound healing index (WHI).

164 gene expression, cellular homeostasis, wound healing, inflammation, allergy, autoimmunity, and oncoge

165 Wound healing is a biological process directed towards restora

166 Bone healing is a complex process with closely linked phases

167 Epithelial wound healing is an evolutionarily conserved process that requ

168 -induced HA synthesis for regenerative wound healing is demonstrated by inhibition of HA synthesis in

169 indings are novel in understanding how wound healing is regulated.

170 Wound healing is significantly delayed in irradiated skin.

171 An important phase of wound healing is the generation of a basal epithelium wholly r

172 The resulting gel is dynamic, can self-heal, is heat responsive, and can be reshaped by postgel

173 rds with a number of similar observations of healed lesions observed in trilobites.

174 d help delineate an altered profile in wound-healing markers during ONJ development.

175 Self-healing materials can repair damage caused by mechanical

176 Osteotomies were created in healed maxillary extraction sites 1) by drilling or 2) b

177 ings provide novel insights regarding unique healing mechanisms of amnion.

178 tion, may utilize mechanically induced, self-healing mechanisms that allow the hole to be closed afte

179 erein introduce an improved in situ membrane healing method using amine-functionalized silica micropa

180 r and molecular processes involved in tissue healing might lead to scar formation.

181 o FHs promote tissue regeneration in a wound-healing model of mouse submandibular glands (mSMGs).

182 nly in hypertension, but also in the case of healed myocardial infarction.

183 In healing myocardial infarction, myofibroblast- and cardio

184 fter molar extraction, sites were allowed to heal naturally or received RP with freeze-dried bone all

185 inflammatory bowel disease, complete mucosal healing occurs in fewer than 50% of patients.

186 One week after healing of abutments, rats were infected with Porphyromo

187 SCs in the regulation of inflammation during healing of acute tendon injuries.

188 at NAC alters the vascular milieu to improve healing of amputation stumps in diabetes using a novel i

189 f AQP3 to the mechanism of EPO action on the healing of burn wounds in the skin of pigs with experime

190 technology to address this issue is in situ healing of compromised membranes via healing agents that

191 aid its clinical relevance of promoting the healing of corneal epithelium debridement.

192 The healing of cutaneous wounds is dependent on the progress

193 est that this preparation of PRP accelerates healing of cutaneous wounds only as a controlled release

194 All 3 patients noted significant healing of erosions and plaques starting from the periph

195 tact lenses, was associated with significant healing of existing lesions.

196 he fetal membrane closed within 72 h whereas healing of large ruptures was only 40%.

197 respondingly, AQP3(-/-) mice showed impaired healing of superficial wounds in the colon and impaired

198 characterized by proteins involved in wound healing, ongoing fibrosis, and inflammation.

199 produce tunably non-Gaussian, partially self-healing optical modes.

200 vessel regression during development, wound healing or IFNgamma-mediated, pregnancy-induced remodell

201 not provide an objective measure of fracture healing or weight bearing for lower extremity fractures.

202 l cells move randomly; however, during wound healing, organism development, cancer metastasis, and ma

203 were coupled with cryoablation to create non-healing osteonecrotic defects in the diaphysis of the mu

204 on from specific experimental studies on the healing pattern of the interface between the root surfac

205 To assess the vessel-healing pattern of Ultimaster drug-eluting stent using o

206 TNFalpha and IL-1beta during the early wound healing phase and reduced inflammation by downregulating

207 ownregulating IL-1beta during the late wound healing phase.

208 This self-healing polymer-beta-sheet peptide hybrid hydrogel with

209 and should enable development of tough, self-healing polymers of practical usage.

210 le to the pristine strength of existing self-healing polymers.

211 cytic lineage inhibit hematopoiesis and bone healing, potentially by producing excessive amounts of D

212 R values and van Hemert scale scores, as the healing process advanced on serial measurements at each

213 al cellular traits associated with the wound healing process and may also be able to regulate the res

214 ies a potential regulatory role in the wound healing process and, thus highlights their potential as

215 fillings, do not directly participate in the healing process in a bioinstructive manner.

216 In chronic nonhealing wounds, the healing process is disrupted and wounds are often infect

217 roid, dexamethasone, and promotes the tissue healing process.

218 which are sequentially recruited during the healing process.

219 sence of LPA1 mitigates the epithelial wound healing process.

220 cation defects without any adverse effect on healing process.

221 function of DM in corneal endothelial wound healing process.

222 cture of time) appeared to be central to the healing process.

223 e favorable biomechanical behavior and strut healing profile compared with BVS in normal porcine coro

224 ared the biomechanical behavior and vascular healing profile of a novel thin-walled (115 microm) siro

225 The cutaneous wound-healing program is a product of a complex interplay amon

226 cond messenger and master regulator of wound-healing programs, it is unknown what initiates the rise

227 application is demonstrated by investigating healing progression and endothelial cell migration in th

228 rium system in tandem with its inherent self-healing properties and triggered release functionality.

229 CMR and increases in inflammation and wound healing proteins on post-MI day 7.

230 overcome limitations of dis/reconnection of healing/provisional abutments (PAs).

231 adjunctive modality in the treatment of non-healing radiation wounds.

232 with gastric IM change may have a higher GU healing rate than those without gastric IM.

233 Patients with IM had a higher GU healing rate than those without IM (91.9% vs. 84.3%, P =

234 d the participants with improved ulcers, the healing rates increased to 94.7%, 97.3%, and 89.7% respe

235 The primary endpoint was healing rates of HD-CU at 14 days after treatment.

236 ogenesis, promoting corneal epithelial wound healing, regulating gene expression and maintaining corn

237 ) strongly regulated the expression of wound healing-related genes.

238 echanism by which NO modulates corneal wound healing remains unclear.

239 Lung fibrosis is an unabated wound healing response characterized by the loss and aberrant

240 olymer-free) on neointimal proliferation and healing response in the familial hypercholesterolemic sw

241 may alter the homeostatic balance and wound-healing response of gingival connective tissues affected

242 molecular mechanisms underlying the altered healing response of RDEB.

243 n the heart, acute injury induces a fibrotic healing response that generates collagen-rich scarring t

244 tiviral host defense during the normal wound healing response.

245 TX3 mediated the hepatic stellate cell wound-healing response.

246 e tissue regeneration in which classic wound-healing responses predominate.

247 domains, has roles in vasculogenesis, wound healing responses, and fibrogenesis and is upregulated i

248 nerating myofibroblasts and associated wound-healing responses.

249 n, the blinking reflex, and epithelial wound healing, resulting in loss of transparency and vision.

250 Within 4 months of healing, rhBMP-2-treated sites showed better radiographi

251 kin microbiome dominated and caused impaired healing, shown in cross-fostering experiments of wild-ty

252 s, and crusts, EPD is difficult to treat and heals slowly.

253 adult nervous system has little ability to 'heal' spinal connections, and it is assumed to be unable

254 ture rupture of membranes (pPROM), membranes heal spontaneously and pregnancy continues until term.

255 calized cutaneous leishmaniasis (LCL), which heals spontaneously, or mucosal leishmaniasis (ML), char

256 stress responses and apoptosis at the wound healing stage, signaling pathways including Wnt and TGFb

257 The in situ healing technique recovered the particle rejection of co

258 ent mechanical and histologic changes of the healing tendon in a transected rabbit model of the Achil

259 be used to objectively assess a diseased or healing tendon.

260 Detecting and healing these hidden wounds may help prevent and treat p

261 gels are highly dynamic, adaptable, and self-healing, those derived from lipoic acid are rigid, resil

262 n of 0.5% PVI could promote acute skin wound healing though increased expression of TGF beta leading

263 Second, osteotomies were produced in healed tooth extraction sites and therefore represented

264 tions such as normal aorta, lungs, and wound healing, tumors, and placenta, as well.

265 Secondary outcome was assessment of wound healing using a wound healing index (WHI).

266 on rabbit corneas during UVB irradiation and healing (UVB doses 1.01 J/cm(2) once daily for four days

267 Tendon injuries heal via scar tissue rather than regeneration.

268 enitor cells regulate inflammation in tendon healing via JNK and STAT3 signaling.

269 in patients with symptomatic IBD in mucosal healing vs patients with asymptomatic IBD in mucosal hea

270 ar inhibition of myofibroblast formation and healing was also observed in a dermal wounding model wit

271 Mucosal healing was defined as CD Endoscopic Index of Severity o

272 Scaffold strut healing was evaluated in vivo using weekly optical coher

273 Healing was followed for 4 months.

274 , which is normally present in wounds, wound healing was impaired.

275 Contrary incomplete socket healing was noted after extraction of teeth with EP in Z

276 understand how stress signals inhibit wound healing, we investigated the role of membranous glucocor

277 rate a functional ES-TUBB3 axis in cutaneous healing, we showed increased TUBB3(+) melanocytes and me

278 Amputation stump tissue perfusion and healing were evaluated in C57BL/6J adult mice with strep

279 Patients' hopes for healing were often unrealistic, posing challenges for th

280 Several cytokines relevant to healing were upregulated during storage.

281 s, such as graft infection and delayed wound healing, were seen in 6 patients; 8 patients experienced

282 HTS is the result of dysregulated wound healing, where excessive collagen and extracellular matr

283 er Pseudomonas species directly impair wound healing, wild-type mice were infected with Pseudomonas a

284 and nonresolving inflammation in myocardial healing will help to develop novel targets with major em

285 00a4) suggesting that EP4cKO(S100a4) repairs heal with increased infiltration of EP4 expressing alpha

286 re; EP4 (flox/flox) (EP4cKO(S100a4)) repairs healed with improved gliding function at day 14, followe

287 infiltrates, 1 (0.1%) had delayed epithelial healing with dendrites, and 3 (0.4%) had recurrent epith

288 scans showed a progressive long-term retinal healing with reappearance of the ellipsoid line and visu

289 lted in significantly impaired scratch wound healing, with delayed migration and reduced proliferatio

290 hanism for DNA breakage followed by telomere healing, with the formation of more accessible chromatin

291 can lead to cell death, if not prevented or healed within an appropriate time.

292 e height was found in molar sites allowed to heal without RP on the buccal aspect of the socket (RP:

293 Membranes that have the ability to self-heal would recover their original rejection levels auton

294 omplication that can result in delayed wound healing, wound breakdown, fistula formation, and comprom

295 tural capacity to replace dying cells and to heal wounds.

296 alters the ultimate mechanical properties of healed wounds will be important to develop more effectiv

297 emotherapy for recurrence and those with non-healing wounds or active bleeding conditions were inelig

298 anscription factor c-Myc (a biomarker of non-healing wounds), in porcine and human wound models.

299 are increasingly recognized to be capable of healing wounds.

300 ulating Fgfbp1-expressing cells migrate into healing wounds.