ライフサイエンスコーパス: healing

1 lving and nonresolving pathway in myocardial healing.

2 ) accelerates the process of acid burn wound-healing.

3 ) to determine the function of MLL1 in wound healing.

4 rs and conditions can lead to impaired wound healing.

5 pathogen defense, organ rejection, and wound healing.

6 ot interfere with skin development and wound healing.

7 obiota over time and their associations with healing.

8 duced FPD development by promoting FPD wound healing.

9 volved in developmental regulation and wound healing.

10 the fracture callus and for undisturbed bone healing.

11 (TM) play a role in skin integrity and wound healing.

12 organized collagen formation and poor tissue healing.

13 d angiogenesis, especially in diabetic wound healing.

14 ic bone were associated with impaired socket healing.

15 t are likely associated with improved tendon healing.

16 vement of keratinocytes in connective tissue healing.

17 for osteoarthritis (OA) and diminished wound healing.

18 ying regenerative vs non-regenerative tendon healing.

19 regeneration, resulting in delayed fracture healing.

20 tical bone, as well as asymmetry in fracture healing.

21 ayed repair, and TIP39 treatment accelerated healing.

22 olonged inflammatory phenotype in late wound healing.

23 2 polarization of macrophages in acute wound healing.

24 vs patients with asymptomatic IBD in mucosal healing.

25 rogressive fashion promotes pathologic wound healing.

26 vo for their ability to promote dermal wound healing.

27 AK, ASK1, and PP5 in ATII cells during wound healing.

28 the beneficial effects of PTH2R signaling on healing.

29 uired altered cutaneous bacteria and delayed healing.

30 d to altered long bone properties and callus healing.

31 arginine uptake mediates AS II-induced wound healing.

32 2 ulcer pathogenesis, severity, or prolonged healing.

33 icacy of platelet-derived proteins for wound healing.

34 to study collective cell migration and wound healing.

35 hown to promote the corneal epithelial wound healing.

36 exogenous NO donor (NaNO2) on corneal wound healing.

37 interrupts tissue remodeling in normal wound healing.

38 prove keratinocyte differentiation and wound healing.

39 normally stimulate multiple phases of wound healing.

40 of the pelvic floor improves perineal wound healing.

41 related miRNAs with potential roles in wound healing.

42 cx in cortical bone development and fracture healing.

43 during papilloma induction and during wound healing.

44 nd deficiencies in the MMP9 lead to impaired healing.

45 macrophages and play central roles in wound healing.

46 e potential to induce angiogenesis and wound healing.

47 aspect of re-epithelialization during wound healing.

48 lating cellular traits associated with wound healing.

49 nderstood inputs for organogenesis and wound healing.

50 uld promote fast and scarless gingival wound healing.

51 s of chronic inflammation, cancer, and wound healing.

52 vant to cancer, vascular diseases, and wound healing.

53 eria can colonize the wound and impair wound healing.

54 nt in 16.3% of patients with IBD and mucosal healing (15.4% of patients with CD, 17.4% with UC).

55 hness, damping, fatigue resistance, and self-healing ability is required.

56 top and bottom molecules, revealing the self-healing ability of the beta roll stack.

57 estal, or subcrestal (-1.5 mm) position, and healing abutments were connected.

58 a concentration-dependent incidence of wound healing adverse events (WHAE).

59 production is essential for intestinal wound healing after colonic surgery, possibly via its effects

60 Perineal wound healing after eAPR with preoperative radiotherapy for re

61 est that 3S may be used to safely accelerate healing after injury in diverse clinical contexts.

62 sor is an effective tool to help assess bone healing after internal fixation and could provide an obj

63 or T cells in profibrotic cardiac repair and healing after ischemia, little is known about whether T

64 Thus, the PGE2/Ep3 axis promotes cardiac healing after MI by activating reparative Ly6C(low) Mos/

65 Ep3 deletion in Mos/Mps markedly attenuates healing after MI by reducing neovascularization in peri-

66 ns, overcoming limitations faced by previous healing agents such as chitosan agglomerates.

67 in situ healing of compromised membranes via healing agents that are added to the feed side of a memb

68 pha3beta1 promotes this process during wound healing, alpha9beta1 has an inhibitory role, suggesting

69 ly incorporate treatment to accelerate ulcer healing and address MRSA into the care of diabetic patie

70 t the 10-lipid mixture, because of its wound-healing and antimicrobial properties, can be beneficial

71 cx-mutant mice demonstrated disrupted callus healing and asymmetry.

72 iation, and migration and in epidermal wound healing and barrier repair.

73 life, and the association between intestinal healing and disease progression in high-risk patients, a

74 MicroRNAs (miRs) play a role in healing and host response to bacterial pathogens.

75 d cell behaviors to those activated in wound healing and identifies a repertoire of potential targets

76 tical tools with in vivo models of osteotomy healing and implant osseointegration to determine if one

77 unity instability was associated with faster healing and improved outcomes.

78 mation of organs, tissue regeneration, wound healing and many disease processes, including cancer.

79 ed exosomes may be involved in corneal wound healing and neovascularization, and thus, may serve as t

80 proteins involved in defense response, wound healing and protein phosphorylation when compared to nor

81 ived, transplanted ASCs can accelerate wound-healing and reduce hair loss in acid-burn skin injury.

82 view presents current understanding in wound healing and regeneration as two distinct aspects of cell

83 signaling on alveolar epithelial cell wound healing and repair, as well as on expression of elastoge

84 ns, while in adult tissues they aid in wound healing and the maintenance of intestinal cell populatio

85 reaction network, they are autonomously self-healing and they are highly adaptive to small changes in

86 levate in vivo levels of PGE2 and to promote healing and tissue regeneration.

87 al WNT-driven alveolar epithelial cell wound healing and transdifferentiation in vitro.

88 ties to prevent infection of burn wound, aid healing, and an anti-inflammatory dressing material.

89 act allergic and autoimmune responses, wound healing, and anti-microbial defense.

90 ganization in biofilms, embryogenesis, wound healing, and cancer metastasis.

91 tion and is involved in tissue repair, wound healing, and clearance of apoptotic cells and cellular d

92 shown to favor embryonic development, wound healing, and even tumor growth, suggesting more complex

93 ited positive correlations with OA, impaired healing, and inflammatory adipokines.

94 Selective inhibition of cell adhesion, wound healing, and invasion are demonstrated; near-infrared fl

95 ding those related to differentiation, wound healing, and metabolism.

96 critical for embryonic development and wound healing, and occurs in fibrotic disease and carcinoma.

97 cularization are to relieve pain, help wound healing, and prevent limb loss.

98 integrity by the critical means of response, healing, and regeneration.

99 eleted in mice at the late stage of fracture healing, and the effects on healing quality were investi

100 ation of cells in stem cell therapies, wound healing, and the treatment of cancer.

101 propagated tissue damage and impaired wound healing, as occurs after spinal cord injury (SCI).

102 The wound healing assay reveals that inhibiting either BCL2L11 or

103 this short report we will explain the wound healing assay, also known as the "in vitro scratch assay

104 ntestinal cancer cell line Caco-2 in a wound-healing assay, and in mice colon wounds.

105 All cell migration and wound healing assays are based on the inherent ability of adhe

106 Furthermore, cell invasion and wound healing assays together with qRT-PCR determination of ep

107 and promotes healing by using in vitro wound healing assays, human ex vivo and porcine in vivo wound

108 ced migration speeds as measured using wound-healing assays.

109 study aimed to compare the difference in GU healing between H. pylori-infected patients with IM and

110 n the dense fibrin matrix and can be used as healing biomaterial.

111 monstrated that FOXO1 was activated in wound healing but to higher levels in diabetic wounds.

112 ion-free survival by 18%, and improved wound healing by 59%, without affecting mortality.

113 in mice with colitis and accelerates mucosal healing by activating STAT1.

114 glucocorticoid (GC) downregulation of wound healing by interaction with the membrane bound GC recept

115 g mediators of inflammation accelerate wound healing by preventing chronic inflammation and allowing

116 sue loss), and are known as 'surgical wounds healing by secondary intention'.

117 or older and had at least one surgical wound healing by secondary intention, which was slow to heal.

118 particularly to "unexpected" surgical wounds healing by secondary intention.

119 vastatin reverses FPP's effects and promotes healing by using in vitro wound healing assays, human ex

120 cxGFP(+) cells were localized throughout the healing callus after fracture.

121 polymer networks, exhibiting remarkable self-healing capability at room temperature.

122 test the method, we compared well and poorly healing cardiac ventricles using a transgenic fish model

123 During skin wound healing, CD26-positive cells accumulated over time and p

124 The primary endpoint was mucosal healing (CDEIS <4) with absence of deep ulcers 48 weeks

125 Wound healing complications were more prevalent in the bevaciz

126 was the rate of uncomplicated perineal wound healing defined as a Southampton wound score of less tha

127 g the proliferative phase of cutaneous wound healing, dermal fibroblasts are recruited into the clott

128 y a key role in tissue homeostasis and wound healing during Th2-mediated immune responses, such as pa

129 Although the wound healing effects of nitric oxide (NO) are known, the mech

130 tensile loads, and exhibit a remarkable self-healing efficiency.

131 demonstrated clearance of bacteria and wound healing following repeated i.v. administration of activa

132 i1+ cells and hedgehog signaling in enthesis healing, Gli1 expression was examined via lineage tracin

133 Periodontal wound healing has been accelerated by different low-level lase

134 However, the role of Scx in fracture healing has not yet been explored.

135 utoff, 36.2% of patients with IBD in mucosal healing have increased intestinal permeability.

136 and myofibroblast formation in corneal wound healing have not been fully elucidated.

137 A transparent, self-healing, highly stretchable ionic conductor is presented

138 cal processes including embryogenesis, wound healing, host immunity, and tumor suppression.

139 imulation (ES) is known to promote cutaneous healing; however, its ability to regulate reinnervation

140 as a central clinical issue for RDEB, wound healing impairment has been only marginally investigated

141 Bone fracture healing impairment related to systemic diseases such as

142 wever, implanted materials can cause further healing impairments due to the persistent inflammatory s

143 h OA, synovitis, adipokine levels, and wound healing in a pre-clinical obese mouse model of OA.

144 s and mechanism of AS II on intestinal wound healing in both in vitro and in vivo models.

145 eneficial in the treatment of impaired wound healing in diabetes.

146 ensin system is implicated in abnormal wound healing in diabetic and older adults.

147 er significantly accelerated cutaneous wound healing in diabetic mice through facilitating angiogenes

148 ting antiretroviral effects on genital wound healing in future clinical trials.

149 cing Wnt/beta-catenin signaling during ulcer healing in IBD.

150 e, using an in vivo model of cutaneous wound healing in mice, we provide evidence that GPNMB is funct

151 ion, granulation formation, and proper wound healing in mice.

152 cyte cell line and demonstrated potent wound healing in mice.

153 n of epidermal caspase-8 as a model of wound healing in Mus musculus, we analyzed the signaling compo

154 udin, down-regulation had no impact on wound healing in normal scratch assays, but after subjecting t

155 Compared to skin, wound healing in oral mucosa is faster and produces less scarr

156 method can be readily applied to image wound healing in other injured or diseased tissues, or to moni

157 We concluded that corneal endothelial wound healing in rabbits has different outcomes depending upon

158 cells (ATII) are instrumental in early wound healing in response to lung injury, restoring epithelial

159 erexpression significantly accelerated wound healing in STZ-induced diabetic mice.

160 ximately 2 to 4 weeks and better periodontal healing in terms of conventional flap sites.

161 a dampening of the host immune response and healing in the mouse model, and it may provide an altern

162 -acetylcysteine accelerates amputation stump healing in the setting of diabetes.

163 rates, mitotic activity, and osteotomy site healing in type III bone and high endogenous Wnt signali

164 rovascular endothelial cells and, in a wound-healing in vitro assay, impaired cell motility and cytok

165 sa was sufficient to impair epithelial wound healing in vivo.

166 gh distinct, yet overlapping phases of wound healing, including hemostasis, inflammation, proliferati

167 as assessment of wound healing using a wound healing index (WHI).

168 gene expression, cellular homeostasis, wound healing, inflammation, allergy, autoimmunity, and oncoge

169 ors of stress signals, are also potent wound healing inhibitors.

170 Wound healing is a biological process directed towards restora

171 Bone healing is a complex process with closely linked phases

172 Epithelial wound healing is an evolutionarily conserved process that requ

173 -induced HA synthesis for regenerative wound healing is demonstrated by inhibition of HA synthesis in

174 indings are novel in understanding how wound healing is regulated.

175 Wound healing is significantly delayed in irradiated skin.

176 An important phase of wound healing is the generation of a basal epithelium wholly r

177 a treat-to-target strategy (based on tissue healing) is likely to be optimal.

178 idered incapable of responding to damage and healing it, leading to the profound negative environment

179 d help delineate an altered profile in wound-healing markers during ONJ development.

180 Self-healing materials can repair damage caused by mechanical

181 ings provide novel insights regarding unique healing mechanisms of amnion.

182 tion, may utilize mechanically induced, self-healing mechanisms that allow the hole to be closed afte

183 erein introduce an improved in situ membrane healing method using amine-functionalized silica micropa

184 r and molecular processes involved in tissue healing might lead to scar formation.

185 o FHs promote tissue regeneration in a wound-healing model of mouse submandibular glands (mSMGs).

186 claudin-1 and occludin in ex vivo skin wound healing models and tissue samples of acute and chronic h

187 In healing myocardial infarction, myofibroblast- and cardio

188 inflammatory bowel disease, complete mucosal healing occurs in fewer than 50% of patients.

189 One week after healing of abutments, rats were infected with Porphyromo

190 SCs in the regulation of inflammation during healing of acute tendon injuries.

191 at NAC alters the vascular milieu to improve healing of amputation stumps in diabetes using a novel i

192 f AQP3 to the mechanism of EPO action on the healing of burn wounds in the skin of pigs with experime

193 technology to address this issue is in situ healing of compromised membranes via healing agents that

194 aid its clinical relevance of promoting the healing of corneal epithelium debridement.

195 The healing of cutaneous wounds is dependent on the progress

196 est that this preparation of PRP accelerates healing of cutaneous wounds only as a controlled release

197 The impaired wound healing of diabetic wounds is attributed to low levels o

198 All 3 patients noted significant healing of erosions and plaques starting from the periph

199 tact lenses, was associated with significant healing of existing lesions.

200 he fetal membrane closed within 72 h whereas healing of large ruptures was only 40%.

201 respondingly, AQP3(-/-) mice showed impaired healing of superficial wounds in the colon and impaired

202 Migration and healing of the amnion mesenchymal compartment, however,

203 characterized by proteins involved in wound healing, ongoing fibrosis, and inflammation.

204 produce tunably non-Gaussian, partially self-healing optical modes.

205 vessel regression during development, wound healing or IFNgamma-mediated, pregnancy-induced remodell

206 not provide an objective measure of fracture healing or weight bearing for lower extremity fractures.

207 l cells move randomly; however, during wound healing, organism development, cancer metastasis, and ma

208 were coupled with cryoablation to create non-healing osteonecrotic defects in the diaphysis of the mu

209 on from specific experimental studies on the healing pattern of the interface between the root surfac

210 To assess the vessel-healing pattern of Ultimaster drug-eluting stent using o

211 TNFalpha and IL-1beta during the early wound healing phase and reduced inflammation by downregulating

212 ownregulating IL-1beta during the late wound healing phase.

213 This self-healing polymer-beta-sheet peptide hybrid hydrogel with

214 and should enable development of tough, self-healing polymers of practical usage.

215 le to the pristine strength of existing self-healing polymers.

216 cytic lineage inhibit hematopoiesis and bone healing, potentially by producing excessive amounts of D

217 R values and van Hemert scale scores, as the healing process advanced on serial measurements at each

218 al cellular traits associated with the wound healing process and may also be able to regulate the res

219 ies a potential regulatory role in the wound healing process and, thus highlights their potential as

220 fillings, do not directly participate in the healing process in a bioinstructive manner.

221 In chronic nonhealing wounds, the healing process is disrupted and wounds are often infect

222 re entheses had few Gli1+ cells early in the healing process, with limited recovery of the cell popul

223 roid, dexamethasone, and promotes the tissue healing process.

224 which are sequentially recruited during the healing process.

225 sence of LPA1 mitigates the epithelial wound healing process.

226 cation defects without any adverse effect on healing process.

227 function of DM in corneal endothelial wound healing process.

228 recovery of the cell population later in the healing process.

229 cture of time) appeared to be central to the healing process.

230 e favorable biomechanical behavior and strut healing profile compared with BVS in normal porcine coro

231 ared the biomechanical behavior and vascular healing profile of a novel thin-walled (115 microm) siro

232 The cutaneous wound-healing program is a product of a complex interplay amon

233 cond messenger and master regulator of wound-healing programs, it is unknown what initiates the rise

234 application is demonstrated by investigating healing progression and endothelial cell migration in th

235 rium system in tandem with its inherent self-healing properties and triggered release functionality.

236 We attribute the observed self-healing property to swelling of the pore-filling hydroge

237 CMR and increases in inflammation and wound healing proteins on post-MI day 7.

238 overcome limitations of dis/reconnection of healing/provisional abutments (PAs).

239 tage of fracture healing, and the effects on healing quality were investigated.

240 adjunctive modality in the treatment of non-healing radiation wounds.

241 with gastric IM change may have a higher GU healing rate than those without gastric IM.

242 Patients with IM had a higher GU healing rate than those without IM (91.9% vs. 84.3%, P =

243 d the participants with improved ulcers, the healing rates increased to 94.7%, 97.3%, and 89.7% respe

244 The primary endpoint was healing rates of HD-CU at 14 days after treatment.

245 ogenesis, promoting corneal epithelial wound healing, regulating gene expression and maintaining corn

246 ) strongly regulated the expression of wound healing-related genes.

247 echanism by which NO modulates corneal wound healing remains unclear.

248 Lung fibrosis is an unabated wound healing response characterized by the loss and aberrant

249 olymer-free) on neointimal proliferation and healing response in the familial hypercholesterolemic sw

250 may alter the homeostatic balance and wound-healing response of gingival connective tissues affected

251 molecular mechanisms underlying the altered healing response of RDEB.

252 n the heart, acute injury induces a fibrotic healing response that generates collagen-rich scarring t

253 TX3 mediated the hepatic stellate cell wound-healing response.

254 tiviral host defense during the normal wound healing response.

255 ated myofibroblast differentiation and wound healing responses in cultured pericytes, but domain 4 sh

256 e tissue regeneration in which classic wound-healing responses predominate.

257 domains, has roles in vasculogenesis, wound healing responses, and fibrogenesis and is upregulated i

258 nerating myofibroblasts and associated wound-healing responses.

259 n, the blinking reflex, and epithelial wound healing, resulting in loss of transparency and vision.

260 Within 4 months of healing, rhBMP-2-treated sites showed better radiographi

261 kin microbiome dominated and caused impaired healing, shown in cross-fostering experiments of wild-ty

262 stress responses and apoptosis at the wound healing stage, signaling pathways including Wnt and TGFb

263 The in situ healing technique recovered the particle rejection of co

264 ent mechanical and histologic changes of the healing tendon in a transected rabbit model of the Achil

265 be used to objectively assess a diseased or healing tendon.

266 hown that cell-based therapies improve wound healing, the recruitment of therapeutic cells to blister

267 Detecting and healing these hidden wounds may help prevent and treat p

268 gels are highly dynamic, adaptable, and self-healing, those derived from lipoic acid are rigid, resil

269 n of 0.5% PVI could promote acute skin wound healing though increased expression of TGF beta leading

270 EPO treatment of the burns accelerated their healing through an AQP3-dependent mechanism that activat

271 tions such as normal aorta, lungs, and wound healing, tumors, and placenta, as well.

272 Secondary outcome was assessment of wound healing using a wound healing index (WHI).

273 on rabbit corneas during UVB irradiation and healing (UVB doses 1.01 J/cm(2) once daily for four days

274 enitor cells regulate inflammation in tendon healing via JNK and STAT3 signaling.

275 in patients with symptomatic IBD in mucosal healing vs patients with asymptomatic IBD in mucosal hea

276 ar inhibition of myofibroblast formation and healing was also observed in a dermal wounding model wit

277 Mucosal healing was defined as CD Endoscopic Index of Severity o

278 Scaffold strut healing was evaluated in vivo using weekly optical coher

279 Healing was followed for 4 months.

280 , which is normally present in wounds, wound healing was impaired.

281 Contrary incomplete socket healing was noted after extraction of teeth with EP in Z

282 ermeability in patients with IBD and mucosal healing, we associated impaired intestinal permeability

283 understand how stress signals inhibit wound healing, we investigated the role of membranous glucocor

284 rate a functional ES-TUBB3 axis in cutaneous healing, we showed increased TUBB3(+) melanocytes and me

285 Amputation stump tissue perfusion and healing were evaluated in C57BL/6J adult mice with strep

286 Patients' hopes for healing were often unrealistic, posing challenges for th

287 Several cytokines relevant to healing were upregulated during storage.

288 s, such as graft infection and delayed wound healing, were seen in 6 patients; 8 patients experienced

289 HTS is the result of dysregulated wound healing, where excessive collagen and extracellular matr

290 er Pseudomonas species directly impair wound healing, wild-type mice were infected with Pseudomonas a

291 and nonresolving inflammation in myocardial healing will help to develop novel targets with major em

292 infiltrates, 1 (0.1%) had delayed epithelial healing with dendrites, and 3 (0.4%) had recurrent epith

293 scans showed a progressive long-term retinal healing with reappearance of the ellipsoid line and visu

294 lted in significantly impaired scratch wound healing, with delayed migration and reduced proliferatio

295 hanism for DNA breakage followed by telomere healing, with the formation of more accessible chromatin

296 omplication that can result in delayed wound healing, wound breakdown, fistula formation, and comprom

297 emotherapy for recurrence and those with non-healing wounds or active bleeding conditions were inelig

298 anscription factor c-Myc (a biomarker of non-healing wounds), in porcine and human wound models.

299 are increasingly recognized to be capable of healing wounds.

300 ulating Fgfbp1-expressing cells migrate into healing wounds.