ライフサイエンスコーパス: healthy adult

1 xercise + ACh, ATP, SNP, or KCl infusions in healthy adults.

2 on or hypertrophy in a proportion of active, healthy adults.

3 ntibody response at antigen-sparing doses in healthy adults.

4 s and potential sources of variability among healthy adults.

5 rsely affects cardiovascular risk factors in healthy adults.

6 cardiovascular disease (CVD) among generally healthy adults.

7 allowed in feed) on winter serum 25(OH)D in healthy adults.

8 ssociation between dairy and incident T2D in healthy adults.

9 during cognitive reappraisal in a sample of healthy adults.

10 mponent AR structure in 90% of a group of 29 healthy adults.

11 erly, immunocompromised patients, as well as healthy adults.

12 tions for cardiovascular risk assessment for healthy adults.

13 attention-deficit/hyperactivity disorder, in healthy adults.

14 risk allele on reward systems functioning in healthy adults.

15 transmitter to learning-dependent changes in healthy adults.

16 tudies of the whole body were performed on 5 healthy adults.

17 licited pronounced proliferation in PBMCs of healthy adults.

18 cited robust neutralising antibody titres in healthy adults.

19 16 d) and other reports of medication use by healthy adults.

20 e than 100,000 memory B lymphocytes from two healthy adults.

21 enza vaccination and respiratory symptoms in healthy adults.

22 a that are common asymptomatic colonizers of healthy adults.

23 colonization rate, density, and duration in healthy adults.

24 mismatched peripheral blood lymphocytes from healthy adults.

25 l tablet vaccine against influenza A H1N1 in healthy adults.

26 nctional capacity of the fecal microbiome of healthy adults.

27 llected 4-d food diary information from 1500 healthy adults.

28 es in outcome value did not differ in SZ and healthy adults.

29 a parallel group design was used to study 26 healthy adults.

30 of 496 plasma protein turnover rates from 4 healthy adults.

31 y signal learning on subsequent REM sleep in healthy adults.

32 neonates, young children aged 12-59 mo, and healthy adults.

33 emerging mechanism of disease in previously healthy adults.

34 of coronary heart disease (CHD) in generally healthy adults.

35 of clinical disease in a challenge study of healthy adults.

36 rmance (P=0.0003) in 3,346 young and elderly healthy adults.

37 nit of blood close to the storage limit into healthy adults.

38 e common in over-the-counter supplements for healthy adults.

39 han wild type embryos, they can develop into healthy adults.

40 Videofluoroscopy was performed in 31 healthy adults.

41 cells has not been explored, particularly in healthy adults.

42 degree of interference remains undefined in healthy adults.

43 literacy and numeracy in the same sample of healthy adults.

44 nectivity to the temporopolar seed region in healthy adults.

45 somatic mutations in the blood of otherwise healthy adults.

46 is not associated with CVD risk in generally healthy adults.

47 risks of obesity, T2D, and CVD in apparently healthy adults.

48 and EPA plus DHA) and insulin resistance in healthy adults.

49 ctivating antibodies are readily detected in healthy adults.

50 s with comorbidities was similar to that for healthy adults.

51 We analyzed sera obtained from 16 healthy adults (18-63 years of age), 52 children (2-17 y

52 nes in cognitive processing speed across 106 healthy adults (19.92-88.29 years) who participated in t

53 routine was devised and a cohort of N = 116 healthy adults (20-79 years of age) was studied.

54 state-of-the art neuroimaging methods in 40 healthy adults (21 females, mean age 26.5 years).

55 Monocytes sorted from nonfrail healthy adults (21-40 y) and old (>/=65 y) individuals w

56 re quantified in forearm skin samples from 5 healthy adults (24 +/- 3 years) using western blot analy

57 fibres were placed in the forearm skin of 12 healthy adults (25 +/- 3 years) for graded infusions (0.

58 zed double-blind crossover study in which 32 healthy adults (25.9 +/- 6.6 years of age) were exposed

59 81 healthy adults (44.6 +/- 17.7 years old, 47% male), with

60 se pharmacokinetic trial was conducted in 10 healthy adults 50y to evaluate the acute (24-h) absorpti

61 s should be offered to adult patients (85%), healthy adults (75%), and the parents of a child with a

62 lating monoclonal B cells may be detected in healthy adults, a condition called monoclonal B-cell lym

63 bution of age-related white matter change in healthy adults across the adult lifespan.

64 ct EEHV genomes in necropsy tissue from five healthy adult African elephants.

65 three exercise intensity conditions in nine healthy adults after taking a 1-mg Fluoride tablet.

66 n superior and inferior visual field from 20 healthy adults (age 23-43, median 26 years).

67 Seventeen healthy adults (age 35-65 years) without sleep disorders

68 Twenty healthy adults (age range, 20-65 years) with acne scars

69 ble-blind, placebo-controlled phase 2 trial, healthy adults aged 18-31 years were randomly assigned (

70 icle (VLP) vaccine candidate formulations in healthy adults aged 18-49 years.

71 gunya virus vaccine, VRC-CHKVLP059-00-VP, in healthy adults aged 18-50 years who were enrolled at the

72 a30, was shown to be safe and immunogenic in healthy adults aged 18-50 years.

73 d H7N9 vaccine in an observer-blind study in healthy adults aged 18-64 years.

74 nit (Harrow, Middlesex, UK), we screened for healthy adults aged 18-65 years, with a body-mass index

75 non-pregnant, immunocompetent, and otherwise healthy adults aged 18-65 years.

76 Whole-body MRI was performed in 142 healthy adults aged 19-65 y [mean +/- SD age: 37.0 +/- 1

77 e interval of 3.6 years in 207 well screened healthy adults aged 23-87 years.

78 onse study we enrolled and randomly assigned healthy adults (aged 18-61 years) at eight study sites i

79 Healthy adults (aged 18-65 y, phototypes I-II) were rand

80 Healthy adults (aged 19-40 years) were randomized 1:1:1:

81 d 15-18 years [six boys, five girls]) and 10 healthy adults (aged 22-36 years [five men, five women])

82 intake-amount escalation study, in which 34 healthy adults (aged 35-55 y) consumed escalating amount

83 swallowing tasks by collecting data from 55 healthy adults (ages 18-65).

84 Twenty adults (10 healthy adults and 10 adults with T2DM) were recruited.

85 , independently collected, large cohorts-440 healthy adults and 662 healthy children-using high-resol

86 hed cellular and humoral immune responses in healthy adults and asthmatic patients.

87 HMPV reinfections are common in healthy adults and children, suggesting that the protect

88 t are generally absent in fecal samples from healthy adults and children.

89 to the intestinal microbiota present in 143 healthy adults and compare this response with the respon

90 humoral immunity in antisera of patients and healthy adults and greatly increased the viral binding a

91 d to severe, even fatal, illness in infected healthy adults and led to vaccination of a portion of th

92 Scratching the skin of healthy adults and tape stripping of mouse skin induced

93 neuron-specific transcripts in the blood of healthy adults and those suffering from the neurodegener

94 live attenuated influenza vaccine (pLAIV) in healthy adults, and assessed the ability of 1 or 2 doses

95 These findings mirror those in healthy adults, and encourage replications using larger

96 e deceased organ donors, including children, healthy adults, and individuals with type 1 or type 2 di

97 intestinal or genital tracts of up to 30% of healthy adults, and infection is thought to arise from i

98 can be identified in H7N9-infected patients, healthy adults, and newborn babies.

99 amygdala lesion patients, neuroimaging of 19 healthy adults, and single-neuron recordings in 9 neuros

100 Previous studies suggested that 7 to 15% of healthy adults are colonized with toxigenic Clostridium

101 ces in the structure of the angular gyrus in healthy adults are related to variability in behavioral

102 to the presence of protective antibodies in healthy adults as a mechanism governing protection again

103 fragment is present in the brains and CSF of healthy adults as well as in Alzheimer's patients.

104 In conclusion, lower nephron number in healthy adults associates with characteristics reflectiv

105 rtality, or all-cause mortality in generally healthy adults at this time.

106 Sera obtained from 29 healthy adults before and after primary or secondary bac

107 Here we present results from 181 healthy adults between 64 and 68 y of age who underwent

108 Healthy adults born and raised at moderate altitude (2,0

109 h sampled from the daily interactions of 143 healthy adults, both total language output and patterns

110 white matter in limiting VWM capacity in the healthy adult brain and suggest that white matter may re

111 In the healthy adult brain synapses are continuously remodelled

112 ceptor (CSF1R) signaling for survival in the healthy adult brain, and we have exploited this dependen

113 ed T cells of 5 of 17 HSV-1/VZV-seropositive healthy adults but not in cord blood donors (n = 5).

114 ffects of dietary cholesterol on CVD risk in healthy adults by using systematic review and meta-analy

115 th various important cardiac disorders, as a healthy adult cardiac fibroblast gene co-regulated by ca

116 Twenty-three healthy adults completed a task that measured the unique

117 Twenty healthy adults consumed only vegetable/fruit juices for

118 adults (BDE) and 19 age- and gender-matched healthy adults (CONT).

119 ous idiopathic generalized epilepsies and 40 healthy adult controls.

120 ently of endosomal TLRs, and human pDCs from healthy adult donors produced IFN-alpha in a retinoic ac

121 id progenitor cells from peripheral blood of healthy adult donors.

122 ained from peripheral blood B cells from 110 healthy adult donors.

123 We assessed brain activity in young healthy adults during a vigilant attention task under hi

124 t 24 h, participants with MetS compared with healthy adults excreted 41% less alpha-CEHC (all values

125 In 41 healthy adults experimentally infected with wild-type S.

126 a naturally proliferating alpha-cell from a healthy adult, for which pathway analysis indicated acti

127 zation in asymptomatic persons, we recruited healthy adults from the general population in Allegheny

128 ttention, here we examined their strength in healthy adults given methylphenidate (Ritalin), a common

129 In healthy adult glomeruli, the proendothelial survival fac

130 Given the Se, and Cr intakes for healthy adults, goat and cow yogurts may be important di

131 h yielded the intriguing conclusion that, in healthy adults, higher levels of variability in neuronal

132 We show that in healthy adult human ears, deeper tissue penetration of S

133 nectivity (RSFC) analyses, with data from 33 healthy adult human participants, we demonstrate that (1

134 WM (fast but capacity-limited) mechanisms in healthy adult human subjects.

135 sma was infused as an intravenous bolus in 7 healthy adult human volunteers at </=2 mg/kg to provide

136 (SM1) cortex and the contraction force of 17 healthy adult humans (7 females, 10 males).

137 c signals were recorded from 20 right-handed healthy adult humans who listened to five different reco

138 upper tract (stomach and small intestine) of healthy adult humans.

139 al digestive functions of the upper tract of healthy adult humans: the TIM-1.

140 In healthy adults humans, we investigated the impact of eff

141 ntial losses in productivity among otherwise healthy adults if uncorrected or undercorrected.

142 We enrolled 72 flavivirus-naive healthy adults in a phase 1 double-blinded, randomized,

143 nicity of rVSV-ZEBOV at various doses in 158 healthy adults in Europe and Africa.

144 al respiratory capacity was determined in 21 healthy adults in vivo using NIRS to measure the recover

145 Twenty healthy adults, in sequentially enrolled groups of 10 ea

146 conjugate vaccines against meningococcus in healthy adults, in the broader context of published stud

147 cted by Se status in rectal biopsies from 22 healthy adults, including 11 controls with optimal statu

148 ates neural activity in the angular gyrus of healthy adults, independent of the modality of the seman

149 r inflammation and papillitis in, otherwise, healthy adult individuals.

150 randomized, double-blind, clinical trial in healthy adults inoculated with RSV.

151 sly that alpha-tocopherol bioavailability in healthy adults is higher than in those with MetS, thereb

152 ly lower skeletal muscle blood flow in older healthy adults is not due to augmented sympathetic vasoc

153 from HFD-fed mice with intestinal tumours to healthy adult K-ras(G12Dint) mice was sufficient to tran

154 Among healthy adult kidney donors, the single-nephron GFR was

155 ems-level differences in specialization in a healthy adult lifespan sample (n = 210; 20-89 y).

156 Twelve healthy adult male participants who underwent nasogastri

157 Twelve healthy adult male subjects received 1-L intravenous inf

158 DNL in overweight and/or obese but otherwise healthy adult male subjects.

159 Healthy adult male Wistar rats underwent irradiation wit

160 Six healthy adult males were randomized to receive either si

161 omized trial evaluating single oral doses in healthy adult males.

162 The study population comprised 87 healthy adults (mean age, 25 years) who were grouped acc

163 , randomized, crossover feeding trial in 106 healthy adults [mean +/- SD age: 47 +/- 10.8 y; body mas

164 placebo-controlled, between-subject design, healthy adult men (n = 121) were administered either T o

165 lacebo-controlled, 3-period crossover trial, healthy adult men (n = 21) consumed bars containing no s

166 e results of a clinical study in a cohort of healthy adult men aimed at further discerning the specif

167 ed with insulin resistance in this cohort of healthy adult men and women.

168 the whole-body distribution of (52)Mn(2+) in healthy adult mice by dynamic and static PET imaging.

169 Lineage tracing in healthy adult mice revealed that PAX7+ spermatogonia sel

170 3, -9 and MT1-MMP was found in the retina of healthy, adult mice.

171 l transplant (HCT) recipients and Triplex in healthy adults motivated the initiation of a placebo-con

172 attenuated neurotropism and were safe in the healthy adult mouse brain.

173 Microglia in the healthy adult mouse depend on colony-stimulating factor

174 s (MLpvNG2(+) cells) that were isolated from healthy adult mouse liver by using a "Percoll-Plate-Wait

175 ct electrical interactions in the setting of healthy adult myocardium was predicted by coupling and f

176 A in humans after consumption of raw carrots.Healthy adults (n = 12) consumed a meal containing 300 g

177 people with schizophrenia (SZ) (n = 18) and healthy adults (n = 18).

178 refrontal, parietal and temporal cortices of healthy adults (n = 19) during memory encoding and retri

179 Compared to healthy adults (n = 34, 28 female, 49.7 +/- 9.9 years ol

180 behavioral and electrocortical markers while healthy adults (n = 40) performed a continuous monitorin

181 Healthy adults (n = 521) received 2 vaccine doses (days

182 on spectrum imaging data from neurologically healthy adults (N = 60) was used to map frontostriatal a

183 hin-subject crossover study was conducted in healthy adults (n=17).

184 tes to acute stress exposure, in a sample of healthy adults (n=30) with a history of early childhood

185 Healthy adults (n=333, Mage=70 years) enrolled in the Au

186 Similarly, in 24 healthy adults, neurobehavioral vulnerability to SR expo

187 In 23 healthy adults, neurobehavioral vulnerability to TSD exp

188 -in-human proof-of-concept clinical trial in healthy adults of a prophylactic mRNA-based vaccine enco

189 ome-wide SNP data from 1,320 unrelated young healthy adults of non-Hispanic European ancestry.

190 s at approximately 6-month intervals from 52 healthy adult office workers from Boston, Massachusetts,

191 In most healthy adults, one 15-microg dose of vaccine elicited l

192 f glucose, sucrose, or both with fructose in healthy adults or children with or without diabetes.

193 ing vaccine efficacy (VE[t]) was examined in healthy adult participants (age range, 18-49 years) in a

194 In this preliminary study of 6 healthy adult participants and 11 hormone and nonhormone

195 The initial study cohort comprised 2386 healthy adult participants, who were voluntarily admitte

196 Healthy adults participating in a randomized placebo-con

197 ase of multifocal necrotizing fasciitis in a healthy adult patient, secondary to Haemophilus influenz

198 Ten healthy adult patients presenting with 21 Miller Class I

199 Ten healthy adult patients presenting with twenty-one Miller

200 Healthy adult patients requiring one-stage dental implan

201 Healthy adults performed a computer-gaming style task in

202 e alcohol intoxication (~0.6 g/kg), 35 young healthy adults performed the TAP during functional magne

203 Twenty-three healthy adults performed two sessions of a navigation ta

204 nsitivity of our approach was assessed in 30 healthy adults performing a matching task with their dom

205 In summary, our results indicate that human healthy adult peripheral blood at steady-state consists

206 enhancement of muscarinic excitation in the healthy adult PFC arises via the electrogenic process of

207 with cardiac dilatation and hypertrophy in a healthy adult population.

208 ogenic CNVs in unselected, but assumed to be healthy, adult populations may be associated with unreco

209 We analyse resting-state fMRI data from 98 healthy adults previously categorized as being among the

210 In healthy adults, prior TIV administration decreased humor

211 rus, little is known about how antibodies in healthy adults protect them against reinfection.

212 Two-hundred ninety healthy adults provided information on childhood parenta

213 cilitate non-noxious tactile activity in the healthy adult rat spinal dorsal horn via activation of s

214 1.38 - 2.22) are comparable with values for healthy adult rat ventricles (1.98 - 3.63).

215 Healthy adults received 2 doses of subvirion H3N2v vacci

216 Healthy adults received real or sham tDCS over their dor

217 Ten healthy adults received two-hour controlled-exposure-exp

218 salamanders, newts and zebrafish, where all healthy adults regenerate in response to injury.

219 (AD) affect brain function and cognition in healthy adult samples may help to identify the biomarker

220 e HRV-C-specific antibody response is low in healthy adult sera and that most of the antibody to HRV-

221 previously described the skin mycobiomes in healthy adults, showing lipophilic fungi Malassezia pred

222 emodeling and homeostasis are unclear in the healthy adult skeleton.

223 In healthy adults, sleep restriction without circadian misa

224 enerated new stable isotope labeling data in healthy adult subjects using both heavy water (n = 4) an

225 A prospective cohort study on healthy adult subjects was conducted at the Department o

226 , double-blind, four-way crossover study, 21 healthy adult subjects were exposed at rest in a randomi

227 Healthy adult temporal lobe tissue was obtained during s

228 We identified B cells in peripheral blood of healthy adults that produce PF4/heparin-specific antibod

229 w--by using two 8-d laboratory protocols--in healthy adults that the circadian system and circadian m

230 The aim was to investigate in healthy adults the effects of cocoa flavanol (CF) intake

231 resents best practices for antibiotic use in healthy adults (those without chronic lung disease or im

232 We conducted a cohort study of 60 healthy adults to compare the uncertainty and accuracy i

233 Here we used PET imaging in 40 healthy adults to compare, within individuals, the estim

234 nging from nontrauma-exposed psychiatrically healthy adults to trauma-exposed adults with severe trau

235 ging from nontrauma-exposed, psychiatrically healthy adults to trauma-exposed adults with severe trau

236 In healthy adults, total 8-d ad libitum energy intake was i

237 In healthy adults, two-hour PM2.5 exposure substantially in

238 Twelve healthy adults underwent a 2-week protocol that enabled

239 nalyzed IGH repertoires in 9 allergic and 24 healthy adults using high-throughput DNA sequencing of 1

240 i were added to anticoagulated blood from 12 healthy adults vaccinated with meningococcal serogroup B

241 Eleven healthy adult volunteers (age = 46 +/- 10 years) were in

242 Healthy adult volunteers aged 18-50 years were randomly

243 human typhoid infection model, we recruited healthy adult volunteers aged between 18 and 60 years, w

244 ycoprotein of Zaire ebolavirus (ZEBOV) to 60 healthy adult volunteers in Oxford, United Kingdom.

245 label, phase 1 pharmacokinetic (PK) studies, healthy adult volunteers received (1) darunavir/ritonavi

246 PfSPZ ('PfSPZ Challenge') to malaria-naive, healthy adult volunteers taking chloroquine for antimala

247 In a between-subjects design, healthy adult volunteers underwent threat (fear) conditi

248 Sixty healthy adult volunteers were randomized to a single sta

249 during the course of influenza infection in healthy adult volunteers who were previously seronegativ

250 We presented healthy adult volunteers with three types of rare tone-t

251 Consenting healthy adult volunteers, 18-45 years old, were randomly

252 U) and homologous VSV-Ebola vaccine boost in healthy adult volunteers.

253 ipheral blood mononuclear cells (PBMCs) from healthy adult volunteers.

254 and placebo (microcrystalline cellulose) in healthy adult volunteers.

255 e 1, randomised, open-label trials involving healthy adult volunteers.

256 To this end, resting-state MEG data of 22 healthy adults was analysed.

257 In patients and healthy adults we measured 'intentional binding', the pe

258 f hypotheses generated from a prior study of healthy adults, we found that the relative magnitude of

259 ng 2-kb promoter regions of 472 genes in 410 healthy adults, we performed a quadratic regression of r

260 In a cohort of clinically healthy adults, we show that the angular information in

261 le human behavioral and imaging study of 100 healthy adults, we tested whether multitasking training

262 Even in healthy adults, weeks of cognitive training alone led to

263 15 healthy adults were administered in random order saline,

264 Healthy adults were assigned to groups A and B (BCG-naiv

265 Healthy adults were enrolled in a randomized, double-bli

266 - 5 years) and ten older (O: 69 +/- 3 years) healthy adults were passively heated until core temperat

267 Healthy adults were randomized to receive DCS (100 mg; n

268 placebo-controlled interventional trial, 20 healthy adults were randomized to receive either placebo

269 In all three studies, healthy adults were randomly assigned by a computer-gene

270 nity-based sample of 181 cognitively intact, healthy adults were recruited from the Dallas-Fort Worth

271 Fifteen healthy adults were supplemented with creatine and place

272 Purified PBMCs obtained from healthy adults were treated with ANE, nicotine, and/or L

273 ell as CMV-seronegative and CMV-seropositive healthy adults, were included as controls.

274 n pre- and postsynaptic dopamine function in healthy adults, which may serve as a template from which

275 s, gut microbiota, and microbial products in healthy adults while maintaining subject body weights.Af

276 Here we assessed ToM abilities in 55 healthy adults while performing a naturalistic ToM task,

277 Healthy adults who had chronic HCMV infection or were re

278 ontrolled clinical trial was performed in 48 healthy adults who received 2 doses of vaccine or placeb

279 of GS-5806, an oral RSV-entry inhibitor, in healthy adults who received a clinical challenge strain

280 We recruited 18-35-year-old healthy adults who were randomly assigned (1:1) in a dou

281 Nonrandomized crossover trial involving 6 healthy adults who were treated at an academic medical c

282 continuing through October 2011 enrolling 72 healthy adults who were vaccinated 1 year previously wit

283 ess in well-characterized, younger and older healthy adults, who were pre-selected on the basis of ha

284 Healthy adults with 4 to 9 annual genital HSV-2 recurren

285 n phase 1 clinical study was performed on 12 healthy adults with a high-specific-activity carrier-fre

286 We challenged 30 healthy adults with an unattenuated ETEC strain, and col

287 phere inhaled insulin should be reserved for healthy adults with diabetes who do not have pulmonary d

288 We inoculated 61 healthy adults with live RSV and studied protection from

289 with low or medium risk of bias, 6 enrolled healthy adults with normal cognition and 5 enrolled adul

290 In previously healthy adults with otherwise unexplained disseminated/e

291 We vaccinated healthy adults with Ty21a and assessed humoral and cellu

292 s to various categories of visual stimuli in healthy adults with variable levels of literacy, includi

293 rgy optimisation strategies, we recruited 88 healthy adults with varying adiposity and chronic stress

294 emotional faces during functional MRI in 28 healthy adults, with final analyses based on 20 individu

295 ical evaluation of the Triplex vaccine in 24 healthy adults, with or without immunity to CMV and vacc

296 odifies ad libitum energy intake over 8 d in healthy adults without fructose malabsorption.

297 e cognitive training and transfer effects in healthy adults without harmful effects.

298 This recommendation applies to healthy adults without special nutritional needs (typica

299 onal study of 95 HIV-infected and 30 matched-healthy adults, without known cardiovascular disease (CV

300 controlled trial, we randomly assigned (1:1) healthy adult women with a history of recurrent urinary