ライフサイエンスコーパス: healthy aging

1 with a modest decrease in the likelihood of healthy aging.

2 ne in episodic memory is a common feature of healthy aging.

3 t by eating well are important components of healthy aging.

4 modify the trajectory of disease to prolong healthy aging.

5 re enabling more precise characterization of healthy aging.

6 in function at rest is minimally affected by healthy aging.

7 of fat distribution and its association with healthy aging.

8 of circumstances that include but transcend healthy aging.

9 ise as a new therapeutic paradigm to promote healthy aging.

10 to whether cerebral perfusion declines with healthy aging.

11 pathways may be a novel strategy to promote healthy aging.

12 ally associated with tau tracer retention in healthy aging.

13 mostly of skeletal muscle, is important for healthy aging.

14 [4], to identify gut-microbial signatures of healthy aging.

15 , and mechanisms of action in the context of healthy aging.

16 cognitive decline is a genetic component of healthy aging.

17 d vegetables) may have a beneficial role for healthy aging.

18 is therefore a potential strategy to promote healthy aging.

19 orking memory capacity (WMC) associated with healthy aging.

20 omatic stem cells can be enhanced to promote healthy aging.

21 ples) were associated with increased odds of healthy aging.

22 id subclasses at midlife had greater odds of healthy aging.

23 strated the importance of kidney function in healthy aging.

24 oid intake in midlife with the prevalence of healthy aging.

25 urodegenerative pathologies, and may promote healthy aging.

26 age, 1517 women (11.0%) met our criteria for healthy aging.

27 of metformin-based interventions to promote healthy aging.

28 to 83%; P for trend = 0.002) greater odds of healthy aging.

29 scribed frontotemporal pattern of changes in healthy aging.

30 king memory impairments in schizophrenia and healthy aging.

31 via conserved molecular pathways to promote healthy aging.

32 is of the conserved mechanisms that modulate healthy aging.

33 er effect on cardiorespiratory coupling than healthy aging.

34 this complex phenotype into subphenotypes of healthy aging.

35 er cognitive function, and lipid profiles of healthy aging.

36 other factors contributing to long life and healthy aging.

37 about alteration of a key neural circuit in healthy aging.

38 ies, the Canadian Community Health Survey on Healthy Aging (2008-2009), and the Quebec Longitudinal S

39 1) from the Canadian Community Health Survey-Healthy Aging (2008-2009).

40 ted include a centenarian who was a model of healthy aging, a 92-year-old with dementia and clinicall

41 These case histories provide examples of how healthy aging and dementia relate to the degree of patho

42 who were enrolled in longitudinal studies of healthy aging and dementia.

43 , intrinsic evidence for such a link between healthy aging and development in brain structure remains

44 learning and memory and their alterations in healthy aging and diseases.

45 er maintenance of telomere length may confer healthy aging and exceptional longevity in humans.

46 al relaxation velocity declines as a part of healthy aging and is largely prognostically benign.

47 to understand the epigenetic contribution to healthy aging and longevity and the molecular basis of t

48 noncanonical Ahcy enzymes as determinants of healthy aging and longevity.

49 hain deficiencies caused by mtDNA decline in healthy aging and neurodegenerative disease.

50 tory animals can help to distinguish between healthy aging and pathological conditions that may contr

51 om the longitudinal Adult Children Study and Healthy Aging and Senile Dementia Study at the Knight Al

52 ein (HSP) 70 plays an important role in both healthy aging and the stress response to injury.

53 ences exist between the processes of normal "healthy" aging and pathologic age-related neurodegenerat

54 e development of novel drug targets for both healthy aging, and pathological aging such as Alzheimer'

55 rmalities in psychosis, their deviation from healthy aging, and the influence of sex on these measure

56 initial formation of tangles and plaques in healthy aging appeared to be independent of each other.

57 ation of greater height with reduced odds of healthy aging appeared to be more evident among women wi

58 Healthy aging appears to primarily affect a frontal-stri

59 ves to optimize long-term health and promote healthy aging are based on the concept of functional fit

60 nephron GFR remains relatively constant with healthy aging as does glomerular volume.

61 ignificant change between young controls and healthy aging as measured by the GM volume and cortical

62 cation of genetic factors that contribute to healthy aging as well as the chronic conditions common i

63 Centenarians are a model for healthy aging because they have reached the extreme limi

64 e production is beneficial for memory in the healthy aging brain, it might be detrimental in an Alzhe

65 The process of healthy aging can best be described by plotting the traj

66 Healthy aging can lead to impairments in learning that a

67 h unpublished data from 200 individuals of a healthy aging cohort (Erikson et al., Cell 165(4):1002-1

68 The effect on PC of healthy aging compared with aging with RFs or cardiovasc

69 range, 65-84 years; 12 men, 11 women) and 50 healthy aging control subjects (mean age, 73.1 years +/-

70 distensibility between patients with DM and healthy aging control subjects.

71 , we uncover a novel mutational signature in healthy aging endocrine cells.

72 e what methods can be used today to increase healthy aging, forestall the onset of these diseases, an

73 rstand the role of dietary protein intake in healthy aging, greater efforts are needed to coordinate

74 Healthy aging has been associated with decreased special

75 iative emotional learning, but the impact of healthy aging has gone relatively unexplored.

76 resonance spectroscopy ((1)H-MRS) studies on healthy aging have reported inconsistent findings and ha

77 Diet and exercise are determinants of healthy aging; however, the extent to which they affect

78 tion of age-related disease and promotion of healthy aging in humans, and the challenge of possible n

79 orm-specific sirtuin activation may have for healthy aging in humans.

80 were conducted in 329 AA participants in the Healthy Aging in Neighborhoods of Diversity across the L

81 In the Healthy Aging in Neighborhoods of Diversity across the L

82 As part of the Healthy Aging in Neighborhoods of Diversity across the L

83 This study's objective was to investigate healthy aging in older French adults 5 years after a per

84 y of height (</=1.57 m), the OR of achieving healthy aging in the highest category (>/=1.70 m) was 0.

85 out the brain in a nonhuman primate model of healthy aging in which the full complement of Alzheimer'

86 nted several additional phenotypes linked to healthy aging, including lower prevalence of cancer and

87 ells with age, but the changes that occur in healthy aging individuals is less clear.

88 ted prefrontal activity in humans, show that healthy aging induces functional alterations in the rewa

89 tudinal studies of subjects progressing from healthy aging into dementia will enable a detailed under

90 Healthy aging involves the interaction between genes, th

91 Although healthy aging is accompanied by a general decline in mem

92 Overall, our results suggest healthy aging is an overlapping but distinct phenotype f

93 Healthy aging is associated with a decline in basic perc

94 A sedentary lifestyle during healthy aging is associated with decreased left ventricu

95 onic disease prevention and the promotion of healthy aging is critical, especially because obesity, w

96 Additionally, healthy aging is not associated with a decreased rate of

97 longevity, usually focused on centenarians, healthy aging is not associated with known longevity var

98 sability and normative functional beliefs of healthy aging is required in this population to inform i

99 Healthy aging is thought to reflect the combined influen

100 d action of sensory and reward circuits, and healthy aging may be compromised when the expectations d

101 igated the associations of adult height with healthy aging measured by a full spectrum of health outc

102 sis and treatment of testosterone decline in healthy aging men and the associated clinical issues for

103 hese results suggest that the ability of the healthy aging motor cortex to reorganize in response to

104 In a healthy aging normal population, choline/creatine and my

105 of this study was to evaluate the effect of healthy aging on brain incorporation of 11C-AA, before a

106 s have supported the preferential effects of healthy aging on frontal cortex, but reductions in other

107 ith a prudent dietary pattern in relation to healthy aging (P-interaction = 0.005), and among the ind

108 8% (95% CI: 6%, 11%) decrease in the odds of healthy aging per SD (0.062 m) increase in height.

109 n particle sizes are heritable and promote a healthy aging phenotype.

110 d factors associated with GCC thickness in a healthy aging population.

111 NSAIDs) reduces the risk of developing AD in healthy aging populations.

112 upplementation was associated with a greater healthy aging probability among men (relative risk = 1.1

113 hypothesis that muscle insulin resistance in healthy aging promotes increased hepatic de novo lipogen

114 ting white matter microstructural changes in healthy aging provides essential context to clinical stu

115 Normal healthy aging results in changes in Doppler indexes of d

116 Circulating PC levels do not decline with healthy aging; RF exposure at a younger age stimulates P

117 cures to devastating diseases and to foster healthy aging, shows the need to respect public sensibil

118 Investigators in the Chicago Healthy Aging Study (CHAS) reexamined 1,395 surviving pa

119 successfully separate patients with AD from healthy aging subjects.

120 tched for working memory performance with 17 healthy aging subjects.

121 matter loss in parietal regions is a part of healthy aging suggests that diminished rPPC grey matter

122 rences in gray matter reflect the effects of healthy aging that cannot be attributed to AD pathology,

123 With normal or healthy aging, the heart undergoes extensive vascular, c

124 In the RM model of healthy aging, the major regionally distributed effects

125 -by-sex interaction in conversion risk (from healthy aging to mild cognitive impairment (MCI)/AD or f

126 ued genome sequencing of a related phenotype-healthy aging-to understand the genetics of disease-free

127 Healthy aging was assessed in 2007-2009 by using multipl

128 hy compared with usual aging as of age 70 y; healthy aging was based on survival to >/=70 y with main

129 Healthy aging was defined as being free of 11 major chro

130 "Healthy" aging was defined as survival to 70 years or ol

131 When the 4 components of healthy aging were analyzed separately, the AHEI-2010 an

132 , the atrophy pattern in PD was also seen in healthy aging, where it also correlated with the loss of