ライフサイエンスコーパス: hearing

1 middle ear conducts sound to the cochlea for hearing.

2 ted slant - a feature considered crucial for hearing.

3 88V/A88V) mice from degeneration and rescues hearing.

4 ical role in sound localization and binaural hearing.

5 evidence for the role that SLC16A5 plays in hearing.

6 to exhibit a compensated acidosis and normal hearing.

7 terpreting evolutionary changes in mammalian hearing.

8 ransduction are affected before the onset of hearing.

9 on, interoception, balance, respiration, and hearing.

10 in determining the frequency selectivity of hearing.

11 ich may contribute to perceptual deficits in hearing.

12 tern was usually reversed, with participants hearing a single stream with increasing Deltaf1 in the a

13 Self-reported improvement in hearing ability was hard to predict but tended to be sma

14 rom a questionnaire comparing self-perceived hearing ability with Fcomp off and Fcomp on.

15 ry capacity, and pretreatment self-perceived hearing ability.

16 Hearing acuity in treated animals is unaltered at postna

17 valuate the performance of a visually guided hearing aid (VGHA) under conditions designed to capture

18 to be significant predictors: more expected hearing aid benefits, greater social pressure, and great

19 Nose, and Throat specialist ( n = 110) or a hearing aid dispenser ( n = 267) filled in a baseline qu

20 ed to determine the predictors of entering a hearing aid evaluation period (HAEP) using a prospective

21 Delays in hearing aid fitting and CI referral were categorized as

22 audiologists supporting decision-making for hearing aid fitting and CI referral.

23 recording in the pathway facilitated earlier hearing aid fitting for milder impairments.

24 e has also been a national trend for earlier hearing aid fitting in children, the current study demon

25 Data analysis explored the age of diagnosis, hearing aid fitting, and referral for cochlear implant (

26 acle in realization of a totally implantable hearing aid is a lack of reliable implantable microphone

27 estionnaire that focused on attitudes toward hearing aid use postimplantation, patterns of usage, and

28 ion and auditory temporal processing skills, hearing-aid settings, working memory capacity, and pretr

29 Sixty-eight hearing-aid users or candidates were fitted bilaterally

30 The results may be useful for improving hearing aids and setting patients' expectations.

31 Unfortunately, performance with hearing aids and the benefit obtained from using them va

32 ction was attributable to earlier fitting of hearing aids for children with mild and moderate hearing

33 han three times the benefit of our subjects' hearing aids for speech processing in noisy listening co

34 Participants wore the hearing aids in each condition in a counterbalanced orde

35 nd was effective in the individuals treated; hearing aids or cochlear implants did not improve commun

36 dates were fitted bilaterally with nonlinear hearing aids using standard procedures.

37 When managed with hearing aids, this did not have an appreciable effect on

38 Most of them can be treated with hearing aids.

39 totally implantable cochlear- or middle-ear hearing aids.

40 psychopathology when assessed while wearing hearing aids.

41 icipants were 14 young adults, 7 with normal hearing and 7 with bilateral sensorineural hearing impai

42 Dysfunctions of hearing and balance are often irreversible in mammals ow

43 nction, may enable future gene therapies for hearing and balance disorders.

44 he cochleovestibular ganglion (CVG) transmit hearing and balance information to the brain.

45 SIGNIFICANCE STATEMENT: Hearing and balance rely on specialized sensory hair cel

46 n degradation or damage can lead to impaired hearing and balance, we analyzed IE samples by tandem ma

47 biophysical process underlying the senses of hearing and balance.

48 situations in which they may have difficulty hearing and communicating, which may contribute to the d

49 representations of modulated noise in normal-hearing and hearing-impaired listeners.

50 nsequences of transient Schwann cell loss on hearing and might provide insights into the causes of th

51 ession and open perspectives to decipher how hearing and other sensory modalities are integrated at t

52 behaviours linked to sensory stimuli (smell, hearing and vision) both having negative implications fo

53 and visual cortices has been reported after hearing and visual deficits mostly during the developmen

54 However, neurophysiological studies with hearing animals have shown that the central auditory sys

55 d to estimate how well acoustic and electric hearing are combined.

56 aches in Drosophila melanogaster to identify hearing as an important sensory modality in the context

57 tal of 20 children and 15 adults with normal hearing as well as 21 children and 17 adults with mild t

58 th that easily spans the full range of human hearing, as well as that of many other mammals.

59 do not have any functional residual acoustic hearing at low frequencies.

60 ascending (afferent) auditory system before hearing begins.

61 Our sense of hearing boasts exquisite sensitivity, precise frequency

62 cally specialize for voice processing in the hearing brain preferentially reorganize for face process

63 In newborn and post-hearing C57BL/6J and CBA/CaJ mice, histochemical and imm

64 predicted performance for acoustic-electric hearing) can be used to estimate how well acoustic and e

65 The remarkable hearing capacities of mammals arise from various evoluti

66 In normal-hearing children, adult-like processing patterns were fo

67 rates 2-3 times higher in deaf compared with hearing children.

68 bservers performed with higher accuracy than hearing controls across all of these tasks.

69 stimulation using cochlear implants in adult hearing controls and deaf cats.

70 Additionally, in hearing controls, acoustic stimuli were used to assess t

71 syndrome due to characteristic skin lesions, hearing deficiency and keratitis.

72 iated complications which apart from causing hearing deficit, may prove fatal at times.

73 These animals also show high frequency hearing deficits and impaired skeletal muscle regenerati

74 ngation process, and its absence also causes hearing deficits.

75 circuit connectivity that may underlie these hearing deficits.

76 ates to visual phenotype and the presence of hearing deficits.

77 Just before the onset of hearing, descending (efferent) input from cholinergic ne

78 within 30 days, dementia, anxiety disorder, hearing difficulty, or history of drug abuse were exclud

79 note, the predictive effect of self-reported hearing disability was modified by readiness such that w

80 r social pressure, and greater self-reported hearing disability.

81 des a new approach to treating patients with hearing disorders who are refractory to glucocorticoids.

82 increased attention for treatment of genetic hearing disorders.

83 Vision and hearing do not appear specialized based on the relative

84 itory system, specialization for directional hearing does not contribute to source segregation.

85 We Envision Our Future April 1995: Effect of Hearing Enhancement on Medical Status Ratings Twenty-one

86 rich in harmonic structures in our everyday hearing environment, it has remained largely unknown wha

87 to maximize the benefit of acoustic-electric hearing, especially for EAS.

88 Hearing evaluations were conducted at baseline, before e

89 ave frequently found that adults with normal hearing exhibit systematic errors (biases) in their audi

90 Piezo2-null mice have largely normal hearing, exhibiting up to 20 dB elevation in threshold i

91 ergy savings within the comfortable range of hearing for CI users.

92 oset (Callithrix jacchus), across the entire hearing frequency range.

93 Both isoforms provide selective benefits for hearing function by maintaining the functional integrity

94 neuronal silencing and targeted knockdown of hearing genes in the fly's auditory organ elicit abnorma

95 though 4- to 7-year-old children with normal hearing had immature cortical responses, adult patterns

96 lue of an experience or behavior can explain hearing health behaviors in older adults with hearing lo

97 rowing importance of hearing loss and global hearing health care.

98 st a need to evaluate vestibular function in hearing impaired individuals, especially those who exhib

99 sity over time is particularly difficult for hearing-impaired listeners with a sensorineural hearing

100 ons of modulated noise in normal-hearing and hearing-impaired listeners.

101 00), IGF-1 was associated with lower odds of hearing impairment (0.86; 0.73, 1.00) after adjustment f

102 d or absent for listeners with sensorineural hearing impairment (HI).

103 ement for infants with a permanent childhood hearing impairment (PCHI) during 2011-2015 at a U.K. ser

104 th a relative frequency greater than 4% were hearing impairment (three [3%] of 93 patients in the SRS

105 1 appeared to confer some protection against hearing impairment in some older adults warrants replica

106 To study the mechanism of hearing impairment resulting from CABP2 loss of function

107 as immobility, functional decline, visual or hearing impairment, dehydration, and sleep deprivation a

108 Atp6v1b1vtx/vtx mutant mice exhibit profound hearing impairment, which is associated with enlarged en

109 idneys, diabetes, hepatitis, depression, and hearing impairment.

110 sleep deprivation, immobility and visual and hearing impairment.

111 l hearing and 7 with bilateral sensorineural hearing impairment.

112 ese myosins in patients suffering visual and hearing impairment.

113 uced myelination might augment sensorineural hearing impairment.

114 56; hepatitis: OR 1.30; depression: OR 1.47; hearing impairment: OR 1.91) (all P < .05).

115 #267300) often associated with sensorineural hearing impairment; however, mice with a knockout mutati

116 related hearing loss disrupts high-frequency hearing in inbred CD-1 mice.

117 nels and is essential for their function and hearing in mice.

118 auditory neurons is not essential for normal hearing in mice.

119 The mechanics of hearing in rodents such as gerbil pose a challenge to ou

120 Our data define the importance of hearing in the control of Drosophila intermale aggressio

121 tant is most likely responsible for impaired hearing in the shaker-1 mice.

122 h Cx30 has been shown not to be required for hearing in young adult mice, IHCs from Cx30 knock-out mi

123 racterized by progressive loss of vision and hearing is caused by mutations in the clarin-1 gene (CLR

124 SIGNIFICANCE STATEMENT: Normal hearing is important to everyday life, but abnormal audi

125 Here we show that not only touch, but also hearing is involved in this phenomenon.

126 An additional role for Foxo3 in preserving hearing is likely, as low frequency auditory function is

127 udiometric test frequency increase by 6.0 dB hearing level (HL).

128 Forty young normal-hearing listeners (20 musicians and 20 nonmusicians) com

129 Repeated testing of the normal-hearing listeners showed no significant practice effects

130 information for cochlear-implant and normal-hearing listeners.

131 ABSTRACT: Age-related hearing loss (ARHL) is associated with changes to the au

132 ation of aspirin use was not associated with hearing loss (for >6 years of use compared with <1 year,

133 Noise induced hearing loss (NIHL) is a disease that affects millions o

134 : 1.05, 2.05) odds ratios for high-frequency hearing loss (p-trend<0.001 and=0.007), respectively.

135 3.03 (95% CI: 1.44, 6.40) for high-frequency hearing loss (p-trend=0.003), but blood lead was not ass

136 en adults with mild to severe high-frequency hearing loss (seven with extensive DRs, one with patchy

137 sequencing in individuals with sensorineural hearing loss (SNHL) and identified pathogenic mutations

138 Sensorineural hearing loss (SNHL) at birth was associated with a posit

139 ring-impaired listeners with a sensorineural hearing loss (SNHL).

140 The primary endpoint was incidence of hearing loss 4 weeks after final cisplatin dose.

141 V) in Brazil, we identified 3 cases of acute hearing loss after exanthematous illness.

142 rstood how distinct GJB2 mutations result in hearing loss alone or in skin pathologies with comorbid

143 duration of analgesic use and self-reported hearing loss among 55,850 women in the Nurses' Health St

144 etion or duplication syndromes often display hearing loss and behavioral disorders, including ADHD an

145 detection and intervention for sensorineural hearing loss and developmental delay, where appropriate.

146 2013, and point to the growing importance of hearing loss and global hearing health care.

147 2), there was no association between risk of hearing loss and hair color (for black hair vs. red or b

148 loss disorders, such as sudden sensorineural hearing loss and Meniere's disease that are elicited by

149 In this Review, we describe the burden of hearing loss and offer our and others' recommendations f

150 r cells, but not in neurons, causes profound hearing loss and outer hair cell degeneration in mice.

151 gated the relationship between self-reported hearing loss and skin pigmentation by using hair color,

152 nts from the perspectives of the person with hearing loss and their communication partner.

153 Glucocorticoids have been used to treat hearing loss and vestibular dysfunction for many years.

154 The item content of hearing loss assessment tools should seek to capture the

155 background and congenic regions have on the hearing loss associated with Cdh23(c.753)alleles.

156 Mutations of SLC26A4 are a common cause of hearing loss associated with enlargement of the endolymp

157 In childhood, partial hearing loss can produce prolonged deficits in speech pe

158 to date no one has synthesized the range of hearing loss complaints from the perspectives of the per

159 more than 400 human genetic syndromes with a hearing loss component.

160 Temporary hearing loss could cause similar changes at later stages

161 Accelerated age-related hearing loss disrupts high-frequency hearing in inbred C

162 y and how this could relate to sensorineural hearing loss following peripheral impairment.SIGNIFICANC

163 Over 100 non-syndromic hearing loss genes have been identified in mouse and hum

164 In total, we identify 67 candidate hearing loss genes.

165 Efforts to develop gene therapies for hearing loss have been hampered by the lack of safe, eff

166 However, the specific defects that lead to hearing loss have not been described.

167 Cisplatin chemotherapy causes permanent hearing loss in 40-80% of treated patients.

168 ted the association between heavy metals and hearing loss in a general population that includes adult

169 y of Cas9-guide RNA complexes can ameliorate hearing loss in a mouse model of human genetic deafness.

170 osulfate for prevention of cisplatin-induced hearing loss in children and adolescents.

171 iosulfate protects against cisplatin-induced hearing loss in children and is not associated with seri

172 effusion (COME) is the most common cause of hearing loss in children, and known to have high heritab

173 thway could underlie treatable sensorineural hearing loss in DFNA34, CAPS, and possibly in a wide var

174 accharide (LPS)-induced sudden sensorineural hearing loss in guinea pigs.

175 Early onset profound hearing loss in KO mice and lack of information about th

176 ntaining HDAC2 expression levels, preventing hearing loss in LPS-exposed animals and reducing cochlea

177 terozygous mice did not examine or report on hearing loss in mature animals, it has not been clinical

178 ve been linked to syndromic and nonsyndromic hearing loss in mice and humans.

179 a diversity of conductive and sensorineural hearing loss in nearly half of AGS patients, many of whi

180 We observe similar stapes defects and hearing loss in one patient with heterozygous JAGGED1 lo

181 tackle the increasingly important problem of hearing loss in our aging population.

182 e both temporary and permanent noise-induced hearing loss in preclinical studies.

183 applicable to the detection of noise-induced hearing loss in stranded cetaceans.

184 LRP3 causes autosomal-dominant sensorineural hearing loss in two unrelated families.

185 ebselen for the prevention of noise-induced hearing loss in young adults in a phase 2 clinical trial

186 Hearing loss is a major public health concern with no ph

187 and that heterozygous mice actually develop hearing loss late in life.

188 Hearing loss leads to a host of cellular and synaptic ch

189 to validate otoprotection in an in vivo rat hearing loss model.

190 sorder, whereas all other PJVK alleles cause hearing loss of cochlear origin.

191 t tools should seek to capture the impact of hearing loss on everyday life, but to date no one has sy

192 y presented before age 3 years and developed hearing loss or other neurological features including at

193 1 children and 17 adults with mild to severe hearing loss participated.

194 First and foremost, treating hearing loss should be investigated as a means of improv

195 und noise.SIGNIFICANCE STATEMENT People with hearing loss struggle to follow conversations in noisy e

196 Black individuals have a lower risk of hearing loss than do whites, possibly because of differe

197 Recent research has linked age-related hearing loss to impaired performance across cognitive do

198 equency (3, 4, and 6 kHz) were computed, and hearing loss was defined as a PTA>25 dB in adults and PT

199 In the absence of treatment, significant hearing loss was detected in LPS-exposed animals.

200 Hearing loss was identified in 14 (28.6%; 95% CI 16.6-43

201 stratification variables, the likelihood of hearing loss was significantly lower in the sodium thios

202 Children with profound hearing loss were referred for CI assessment at a signif

203 Mid-frequency to high-frequency hearing loss, an expected adverse event, was documented

204 two unrelated individuals with microcephaly, hearing loss, and overlapping dysmorphic features.

205 w-cost possibilities exist for prevention of hearing loss, as do unprecedented opportunities to reduc

206 ere associated with slightly higher risks of hearing loss, but duration of aspirin use was not.

207 The M163V mutant, which causes only hearing loss, exhibited impaired gap junction function a

208 ly similar: severe disability, microcephaly, hearing loss, spasticity, and characteristic brain imagi

209 To determine how ESRP1 mutations cause hearing loss, we evaluated Esrp1(-/-) mouse embryos and

210 atypical association of LCA with early-onset hearing loss, we identified two heterozygous mutations a

211 e are currently no biological treatments for hearing loss, we sought to advance gene therapy approach

212 ssment tools exist to evaluate the impact of hearing loss, with little consensus among researchers as

213 cs has been associated with a higher risk of hearing loss.

214 s pigmentosa (RP) and bilateral neurosensory hearing loss.

215 ns to cochlear hair cells, causing permanent hearing loss.

216 reatment of some types of autosomal-dominant hearing loss.

217 role of GPx1 activity in acute noise-induced hearing loss.

218 llion people worldwide suffer from disabling hearing loss.

219 ion may form the basis for otoferlin-related hearing loss.

220 on (COME) is the leading cause of conductive hearing loss.

221 essment and to evaluate existing measures of hearing loss.

222 eurodegeneration and exacerbates age-related hearing loss.

223 on for both the children and the adults with hearing loss.

224 it a simple differential diagnosis of hidden hearing loss.

225 ead to many skin disorders and sensorineural hearing loss.

226 e central auditory system during age-related hearing loss.

227 earing health behaviors in older adults with hearing loss.

228 ural TFS for older listeners without or with hearing loss.

229 n adolescents may play a role in the risk of hearing loss.

230 correlation between smoking and age-related hearing loss.

231 003), but blood lead was not associated with hearing loss.

232 mulation in the terminal may protect against hearing loss.

233 s alone or in skin pathologies with comorbid hearing loss.

234 th/+) mice substantially reduced progressive hearing loss.

235 anscriptase PCR, or (iii) new vision loss or hearing loss.

236 0.001) were associated with higher risks of hearing loss.

237 use stereociliary bundle disorganization and hearing loss.

238 and it typically presents with sensorineural hearing loss.

239 ochlear hair cell degeneration, and profound hearing loss.

240 gainst cochlear synaptopathy associated with hearing loss.SIGNIFICANCE STATEMENT A single incidence o

241 Atoh1 alleles should be considered in human hearing loss.SIGNIFICANCE STATEMENT The discovery that A

242 A34, CAPS, and possibly in a wide variety of hearing-loss disorders, such as sudden sensorineural hea

243 ing aids for children with mild and moderate hearing losses, for which the median age fell from 19 to

244 lation results suggest acoustic and electric hearing may be more effectively and efficiently combined

245 teraural time differences (ITDs) for spatial hearing may require access to bilateral auditory input d

246 In electrical hearing, multipulse integration (MPI) describes the rate

247 s) that is evident for listeners with normal hearing (NH) is generally reduced or absent for listener

248 l of cochlear hair cells and preservation of hearing, NO-mediated cascades have both protective and d

249 ons by users of different sign languages and hearing nonsigners exhibit marked similarities in the us

250 Using slice recordings before hearing onset and in vivo recordings with iontophoretic

251 moval, animals that had been earplugged from hearing onset throughout auditory critical periods displ

252 pha starts to express in type II SGNs before hearing onset, but the expression level declines in the

253 s with iontophoretic drug applications after hearing onset, we show that cell-specific purinergic mod

254 5, suggesting its existence before and after hearing onset.

255 ing an identifiable modular network prior to hearing onset.

256 egions, ATP responsiveness diminished before hearing onset.

257 ine mechanical measurements of sound-induced hearing organ motion and detailed anatomical investigati

258 igand may play such a role in the developing hearing organ of the bird cochlea.

259 nd cap cell size in the proximal part of the hearing organ while in the distal part of the organ, sma

260 In the present study of a tonotopic insect hearing organ, we combine mechanical measurements of sou

261 Vertebrate hearing organs manifest cellular asymmetries across the

262 The tonotopically organized hearing organs of bushcrickets provide the opportunity f

263 rphological and structural properties within hearing organs that are needed to establish tonotopic gr

264 Mosquitoes use their antennae as hearing organs to locate and interact with one another v

265 etaining the sound of specific words despite hearing other stimuli during encoding.

266 s (STC) we collected fMRI data from deaf and hearing participants (male and female), who either acqui

267 Twenty-four normal hearing participants were asked to localise the position

268 that primarily respond to auditory input in hearing people.

269 total, 377 older persons who presented with hearing problems to an Ear, Nose, and Throat specialist

270 cern with no pharmaceutical intervention for hearing protection or restoration.

271 s have a rich vocal repertoire and a similar hearing range to that of humans.

272 hop examining possible futures of speech and hearing science out to 2030.

273 es produce advertisement calls outside their hearing sensitivity range and their inner ears are partl

274 al dysfunction, alone or in combination with hearing settings, did not affect outcome predictions.

275 In hearing signers, enhanced activation was absent in both

276 Furthermore, hearing signers, with the same sign language experience

277 opamine neurotransmission was elevated after hearing songs.

278 s provide key insights into the evolution of hearing specializations and feeding strategies in early

279 s the lowest frequencies of the pilot whales hearing spectrum.

280 in responses in awake animals in the passive hearing state are modulated dynamically by previous audi

281 by determining the differential effects that hearing status and task demands can have on left and rig

282 To investigate how hearing status, sign language experience, and task deman

283 ing influence of the Cdh23(c.753A)variant in hearing studies of B6 mice and mutant mice on the B6 bac

284 Vowel recognition was measured in normal-hearing subjects listening to simulations of unimodal, E

285 In addition, hearing subjects performed the same task in the auditory

286 Both deaf and hearing subjects performed the task visually, in the cen

287 to CBA/J mice with sensitive high-frequency hearing, suggesting that gap junctions contribute to pas

288 participants' visual search immediately upon hearing the ambiguous object's name (e.g. "teapot").

289 as an obstacle by increasing emissions, but hearing the sonar emissions of the nearby bat partially

290 ABSTRACT: Just before the onset of hearing, the inner hair cells (IHCs) receive inhibitory

291 It has inspired many functional hearing theories.

292 on Chr 13 that accounts for about 20% of the hearing threshold variation in the backcross mice.

293 Our results also show that both hearing thresholds and, to a lesser extent, magnified co

294 Pure-tone average (PTA) of hearing thresholds at high frequency (3, 4, and 6 kHz) w

295 However, elevated high frequency hearing thresholds did not predict demand for informatio

296 esponses but did not affect OHC function and hearing thresholds.

297 esign of future neural prostheses to restore hearing to deaf individuals.SIGNIFICANCE STATEMENT The q

298 Auditory verbal hallucinations (hearing voices) are typically associated with psychosis,

299 formance was best when acoustic and electric hearing was combined in the same ear.

300 nd either GMFCS level 2, active seizures, or hearing with amplification.

301 n with simultaneous bilateral CIs and normal hearing with similar time-in-sound was explored in the p