ライフサイエンスコーパス: hearing impairment

1 vere thyroid hormone deficiency and profound hearing impairment.

2 135G>T [p.Glu379X]) in ILDR1 as the cause of hearing impairment.

3 rlying nonsyndromic prelingual sensorineural hearing impairment.

4 of the mechanisms of hypothyroidism-induced hearing impairment.

5 sleep deprivation, immobility and visual and hearing impairment.

6 th an increased risk of substantial neonatal hearing impairment.

7 ner ear histology suggestive of a conductive hearing impairment.

8 l hearing and 7 with bilateral sensorineural hearing impairment.

9 e unit (NICU), and one of them had bilateral hearing impairment.

10 thyroid hormone dysregulation in age-related hearing impairment.

11 vating neurons is the most frequent cause of hearing impairment.

12 d neural system of the inner ear, leading to hearing impairment.

13 nd travel, among individuals who also have a hearing impairment.

14 t heterozygous mice do not suffer peripheral hearing impairment.

15 d with a higher likelihood of developing any hearing impairment.

16 molecular mechanisms underlying hearing and hearing impairment.

17 autosomal dominant, nonsyndromic hereditary hearing impairment.

18 universal neonatal screening programmes for hearing impairment.

19 egated with the inherited autosomal dominant hearing impairment.

20 a conditioning tone, perhaps attributable to hearing impairment.

21 at least 30 autosomal loci for nonsyndromic hearing impairment.

22 vement in immobility, visual impairment, and hearing impairment.

23 sclerosis is the single most common cause of hearing impairment.

24 ry disorder that causes hypopigmentation and hearing impairment.

25 0 of these children have moderate or greater hearing impairment.

26 RP) with or without congenital sensorineural hearing impairment.

27 CNS mechanisms are affected by a peripheral hearing impairment.

28 ese myosins in patients suffering visual and hearing impairment.

29 icity in the perceptual sequelae of cochlear hearing impairment.

30 gic disease, brain lesions, drug effect, and hearing impairment.

31 uced myelination might augment sensorineural hearing impairment.

32 ptors of the auditory system re-emerges with hearing impairment.

33 ign of damage in both noise- and age-related hearing impairment.

34 oaches and medical care for LF patients with hearing impairment.

35 r, and prognostic indicator, for age-related hearing impairment.

36 , indicating hair cell dysfunction and gross hearing impairment.

37 in a socially excluded group of people with hearing impairment.

38 examined a clinical cohort of subjects with hearing impairment.

39 tation had symmetric, mild-to-moderate mixed hearing impairment.

40 isk for psychosis is observed in people with hearing impairment.

41 idneys, diabetes, hepatitis, depression, and hearing impairment.

42 ty of a link between K(v)1.1 dysfunction and hearing impairment.

43 normal hearing listeners and other forms of hearing impairment.

44 within 19 genetic intervals associated with hearing impairment.

45 or a substantial proportion of patients with hearing impairment.

46 studies in older humans when controlling for hearing impairments.

47 s that cause severe prelingual non-syndromic hearing impairments.

48 e fibers, can lead to profound and permanent hearing impairments.

49 r diagnosis of cerebral palsy and visual and hearing impairments.

50 00), IGF-1 was associated with lower odds of hearing impairment (0.86; 0.73, 1.00) after adjustment f

51 he appropriate compensation of sensorineural hearing impairment across a range of frequencies (e.g.,

52 ous for KARS mutations had symmetric, severe hearing impairment across all frequencies but did not sh

53 family with autosomal dominant nonsyndromic hearing impairment (ADNSHI) was enrolled in this study.

54 Genetic hearing impairment affects around 1 in every 2,000 birth

55 ter than the effects of vision impairment or hearing impairment alone, because when these two sensory

56 Its potential for permanent hearing impairment also emphasizes the need to better un

57 protective effects on hypothyroidism-induced hearing impairment, an F1 intercross was generated betwe

58 n leads to the DFNA17 phenotype (progressive hearing impairment and cochleosaccular degeneration) rem

59 uated and considered in future management of hearing impairment and design of auditory prostheses.

60 l hearing), adjusted for the severity of the hearing impairment and for maternal education.

61 the middle ear, is the most common cause of hearing impairment and surgery in children.

62 ion are advancing molecular understanding of hearing impairment and the complex mechanisms of the aud

63 screening for permanent bilateral childhood hearing impairment and the effects of confirmation of he

64 Variables, including hearing impairment and the presence of visual and other

65 ications for pitch perception in people with hearing impairments and cochlear implants.

66 search tool that can elucidate the nature of hearing impairments and suggest or eliminate compensator

67 e outcomes of disability and death combined, hearing impairment, and adverse events.

68 deprivation, immobility, visual impairment, hearing impairment, and dehydration.

69 suffered from pancytopenia, allergy, asthma, hearing impairment, and mental retardation.

70 children aged 6-19 years have some degree of hearing impairment, and over 216,000 of these children h

71 cluding microcephaly, neurological deficits, hearing impairment, and vision loss.

72 iovascular disease, itself a risk factor for hearing impairment, and, in animal studies, molecular ev

73 a range of adverse listening conditions and hearing impairments, and even for users of cochlear impl

74 is unfolding as genes underlying hereditary hearing impairment are identified.

75 People with hearing impairment are thought to rely heavily on contex

76 Age-related hearing impairment (ARHI) affects 25-40% of individuals

77 Age-related hearing impairment (ARHI), or presbycusis, is the most p

78 damage to the inner ear is a major cause of hearing impairment, arising from exposures occurring dur

79 within the autosomal-recessive nonsyndromic hearing impairment (ARNSHI) locus DFNB68 on 19p13.2.

80 ciated with autosomal-recessive nonsyndromic hearing impairment (ARNSHI), was mapped to chromosomal r

81 e to the aetiology of amblyaudia, a binaural hearing impairment associated with bouts of otitis media

82 dulthood, corresponding with the early onset hearing impairment associated with Mass1frings.

83 formation of the heart and other organs, and hearing impairment associated with recurrent ear infecti

84 Hearing impairment at birth was also less frequent in th

85 onates, both groups with no risk factors for hearing impairment at birth, were included.

86 mpairment and the effects of confirmation of hearing impairment by nine months of age on subsequent v

87 Confirmation of hearing impairment by nine months of age was associated

88 Modern screening tests for hearing impairment can improve identification of newborn

89 family members in three generations: 10 with hearing impairment caused by the DFNA23 locus, 8 unaffec

90 Developmental hearing impairments compromise sound discrimination, spe

91 ogical abnormalities of the external ear and hearing impairment (conductive or sensorineural) affect

92 fects, but three of 11 surviving infants had hearing impairment confirmed on auditory testing between

93 as immobility, functional decline, visual or hearing impairment, dehydration, and sleep deprivation a

94 (DFNB2), and autosomal-dominant nonsyndromic hearing impairment (DFNA11).

95 have been linked to non-syndromic hereditary hearing impairment DFNA17 as well as 'MYH9-related disea

96 me type IB, autosomal-recessive nonsyndromic hearing impairment (DFNB2), and autosomal-dominant nonsy

97 characterized by a pigmentation anomaly and hearing impairment due to lack of melanocyte.

98 ice, in contrast, present with non-syndromic hearing impairment due to the effects of multiple genes

99 Hearing impairment due to the loss of sensory hair cells

100 the lesions but no new hair cells arise and hearing impairment ensues.

101 holistic approaches to health management and hearing impairment, (f) universal access to evolving and

102 iption cofactor Eyes absent 4 (Eya4), causes hearing impairment followed by dilative cardiomyopathy.

103 US population, and prevalences of vision and hearing impairment have been extensively evaluated.

104 Hearing impairment (HI) is prevalent, is modifiable, and

105 d or absent for listeners with sensorineural hearing impairment (HI).

106 #267300) often associated with sensorineural hearing impairment; however, mice with a knockout mutati

107 ry, smoking, body mass index, and vision and hearing impairment (HR = 1.05, 95% CI = 1.03-1.07, p < 0

108 tudied 120 children with bilateral permanent hearing impairment identified from a large birth cohort

109 reduced hearing ability and the duration of hearing impairment in 42 unilateral hearing loss (UHL) p

110 0 on screening for age-related sensorineural hearing impairment in adults aged 50 years or older with

111 ions and 2) modifiable factors contribute to hearing impairment in adults.

112 which may have changed temporal patterns of hearing impairment in adults.

113 The condition began with high-frequency hearing impairment in all family members excluding III:2

114 effect of birth cohort on the prevalence of hearing impairment in an adult population aged 45-94 yea

115 tations in the POU domain gene Brn-3c causes hearing impairment in both the human and mouse as a resu

116 OM remains the most common cause of hearing impairment in childhood.

117 otic capsule are common causes of conductive hearing impairment in children and adults.

118 Because CSOM is the commonest cause of hearing impairment in children in these countries, an ef

119 the duration of MEE and possible concomitant hearing impairment in children with AOM.

120 iants co-segregates with congenital profound hearing impairment in consanguineous Pakistani families

121 mtDNA mutations predisposing to hearing impairment in humans are generally homoplasmic,

122 tated the identification of genes that cause hearing impairment in humans.

123 icate that the short nose, otitis media, and hearing impairment in Jacobsen syndrome are likely becau

124 we link a previously uncharacterized gene to hearing impairment in mice and humans.

125 of candidate genes to late-onset progressive hearing impairment in mouse and human.

126 F) recommendation statement on screening for hearing impairment in older adults.

127 l function are important contributors to the hearing impairment in Pit1(dw) mice.

128 1 appeared to confer some protection against hearing impairment in some older adults warrants replica

129 aring loss (NSHL) is the most common type of hearing impairment in the elderly.

130 lea accounts for a significant proportion of hearing impairment in the population.

131 o national guidelines, and the prevalence of hearing impairment in the two groups was compared by usi

132 The prevalence of hearing impairment in these neonates was determined, wit

133 amily with X-linked postlingual nonsyndromic hearing impairment in which the critical linkage interva

134 the genetic and physiological bases of human hearing impairment, including both early- and late-onset

135 a range of adverse listening conditions and hearing impairments, including cochlear implant-supporte

136 , TR beta 2-null mice exhibit no evidence of hearing impairment, indicating that TR beta 1 and TR bet

137 Hearing impairment is 1 of the 4 most prevalent chronic

138 Given that the frequency of all childhood hearing impairment is 1/1,000 and that half of that is g

139 There are >400 disorders in which hearing impairment is a characteristic of the syndrome,

140 Pediatric hearing impairment is a chronic handicap that can potent

141 Hearing impairment is a common human condition, but we k

142 Functional simulation of sensorineural hearing impairment is an important research tool that ca

143 As newborn screening for hearing impairment is being implemented in many birth ho

144 Hearing impairment is clinically and genetically heterog

145 Hearing impairment is common in adults with diabetes, an

146 Although hearing impairment is common in patients with mtDNA defe

147 genetic deafness is non-syndromic, in which hearing impairment is not associated with any other abno

148 of middle ear effusion (MEE) and concomitant hearing impairment is not known.

149 mporal resolution in listeners with cochlear hearing impairment is presented with the aim of assessin

150 autosomal dominant late-onset non-syndromic hearing impairment is segregating, we have identified a

151 Hearing impairment is the most common sensory deficit.

152 Hearing impairment is the most common sensory disorder,

153 Late-onset non-syndromic hearing impairment is the most common type of neurologic

154 Severe deafness or hearing impairment is the most prevalent inherited senso

155 ion.The full extent of the genetic basis for hearing impairment is unknown.

156 the link between IGF-1 and the occurrence of hearing impairment is untested in population-based studi

157 ied mutation in CABP2 that causes a moderate hearing impairment likely via nonsense-mediated decay of

158 y, a novel autosomal recessive non-syndromic hearing impairment locus DFNB44 was mapped to chromosome

159 generation and a moderate but nonprogressive hearing impairment, mimicking the visual and hearing def

160 for blindness (0.9% vs 0%; P = .02), and for hearing impairment (moderate and severe, 0.9% vs 0%; P =

161 sifiable category where 67.2% had documented hearing impairment, more than in any other group (P < 0.

162 benefit to individuals in all categories of hearing impairment (normal, mild, moderate, severe, and

163 Autosomal recessive non-syndromal hearing impairment (NSRD) is genetically heterogeneous.

164 mbers, consistent with the optic atrophy and hearing impairment observed in human patients.

165 ho had confirmed bilateral OME and bilateral hearing impairment of 25-70 dB of at least 3 months' dur

166 mutation is responsible for the early onset hearing impairment of BUB/BnJ mice.

167 y, age-adjusted prevalence of high-frequency hearing impairment of mild or greater severity in the wo

168 adjusted prevalence of low- or mid-frequency hearing impairment of mild or greater severity in the wo

169 Children with bilateral permanent hearing impairment often have impaired language and spee

170 uditory hair cell defect is a major cause of hearing impairment, often leading to spiral ganglia neur

171 uditory brainstem responses indicated a mild hearing impairment on hair cell-specific deletion of all

172 The rate of hearing impairment or deafness was found to be 0% (0 of

173 Hearing impairment or vestibular dysfunction in humans o

174 85); deafness (OR, 2.19; 95% CI, 1.17-4.12); hearing impairment (OR,1.55; 95% CI, 1.29-1.87); upper e

175 tory factors such as neurological disorders, hearing impairment, or lack of adequate opportunity-are

176 56; hepatitis: OR 1.30; depression: OR 1.47; hearing impairment: OR 1.91) (all P < .05).

177 rt, IGF-1 was not associated with subsequent hearing impairment (OR5nmol/L increase; 95% CI: 1.01; 0.

178 They exhibited hearing impairment, otitis media, fusions of ossicles to

179 , personal or parental history of migration, hearing impairment, parental age, parental income, paren

180 ement for infants with a permanent childhood hearing impairment (PCHI) during 2011-2015 at a U.K. ser

181 born screening (UNS) for permanent childhood hearing impairment (PCHI) was undertaken to establish wh

182 riants both segregated with the nonsyndromic-hearing-impairment phenotype within the three families,

183 ost common sensory disorder, with congenital hearing impairment present in approximately 1 in 1,000 n

184 This hearing impairment progressed with age.

185 The enrichment of hearing impairment-related genes in the SOC may have imp

186 e brain revealed a significant enrichment of hearing impairment-related oligos in the SOC (26 in the

187 ents surviving BTs were at elevated risk for hearing impairments (relative risk [RR], 17.3; P = <.000

188 ad an increased risk of exacerbations but no hearing impairment, resting tachycardia, or apparent ris

189 To study the mechanism of hearing impairment resulting from CABP2 loss of function

190 hose with missense mutations; development of hearing impairment showed a similar trend.

191 nt was independent of known risk factors for hearing impairment, such as noise exposure, ototoxic med

192 he acoustic startle response consistent with hearing impairment, suggesting a novel role for Rsph9 in

193 lying neurodegenerative disorder or isolated hearing impairment tended to hear more persistent music,

194 ently believed to be permanent, resulting in hearing impairment that affects more than 10% of the pop

195 air cell survival and therefore minimize the hearing impairment that normally occurs with aging and/o

196 with universal newborn screening and 57 had hearing impairment that was confirmed by nine months of

197 Tecta domains causing mid- or high-frequency hearing impairments that are either stable or progressiv

198 e been linked to the most frequent monogenic hearing impairment, the recessive isolated deafness DFNB

199 th a relative frequency greater than 4% were hearing impairment (three [3%] of 93 patients in the SRS

200 Symptoms such as hearing impairment, tinnitus, or a disturbance in sense

201 The data linking hearing impairment to incident late-life depression are

202 We locate the cause of the hearing impairment to the middle ear, demonstrating over

203 ew locus-DFNA17, for nonsyndromic hereditary hearing impairment-to chromosome 22q12.2-q13.3.

204 The prevalence of hearing impairment was 1% (one of 96; 95% confidence int

205 Hearing impairment was assessed from the pure tone avera

206 Early detection of childhood hearing impairment was associated with higher scores for

207 Hearing impairment was common, particularly in the not o

208 Hearing impairment was defined as a pure-tone average of

209 Hearing impairment was first detected at 3 weeks of age,

210 The association between diabetes and hearing impairment was independent of known risk factors

211 Hearing impairment was more penetrant and stapes malform

212 Hearing impairment was more prevalent among adults with

213 hildren and 0.0% of controls (P < .001), and hearing impairment was observed in 2.1% of extremely pre

214 for low- or mid-frequency and high-frequency hearing impairment were 1.82 [CI, 1.27 to 2.60] and 2.16

215 r increase in birth year, the odds of having hearing impairment were 13% lower in men (odds ratio = 0

216 severe, sloping, symmetrical, sensorineural hearing impairment were fitted with hearing aids.

217 of the baseline scores paralleled degree of hearing impairment when impairment was defined using a b

218 t at 4 weeks most showed variable degrees of hearing impairment, which became severe or profound in a

219 Four subjects from three families reported hearing impairment, which has not previously been report

220 Atp6v1b1vtx/vtx mutant mice exhibit profound hearing impairment, which is associated with enlarged en

221 fferent types of gene products can result in hearing impairment, which, given the complexity of the a

222 This stop-gained mutation segregated with hearing impairment within the family and was not identif