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1 trimers, potentially via a coiled-coil alpha-helix.
2 in mechanism involving the amphipathic alpha-helix.
3 ed on the formation of a parallel DNA triple helix.
4 urbs the conformation of its DNA-recognition helix.
5  pendants positioned on the same side of the helix.
6 ellin monomers are arranged in a left-handed helix.
7 finding that human calcitonin forms an alpha-helix.
8 of the microparticles was of a V-type single helix.
9 ide chains arranged along one side of the 14-helix.
10  as if transitioning between the ends of the helix.
11 ond transmembrane segment and major coupling helix.
12 ural and dynamic perturbations in the double helix.
13 tolabeled residues (V954 and E969) in the S6 helix.
14 ered flexibility from the N terminus through helix 1 and modulated the RcnR-DNA interaction.
15 ing to RcnR orders its N terminus, decreases helix 1 flexibility, and induces conformational changes
16                               (2)H uptake in helix 1 was suppressed in the Ni(II)- and Co(II)-bound R
17 vealed water penetration along transmembrane helix 1 with the cooperation of a polar residue (Y147 in
18 al aromatic and hydrophobic residues in pore helix 1, helices S5 and S6, and helix S6 of a neighbouri
19 include a distinct movement of transmembrane helix 2 (M2), from its position in the previously report
20 nalysis revealed that the flexibility of the helix 3, 7, and 11 regions represents the most important
21  four lipid-facing residues in transmembrane helix 4 (TM4) that is known to be important for dimeriza
22 a are antimicrobial, we synthesized IFN-beta helix 4 and found that it is sufficient to permeate mode
23 f the IFN-beta molecular surface (especially helix 4) are cationic and amphipathic, both classic char
24 on of a polar residue (Y147 in transmembrane helix 5) in the adjacent protomer.
25  a sharp kink in the middle of transmembrane helix 6, which pivots its intracellular half outward to
26                   To improve sampling of the helix 6-7 loop, we incorporated motion modes based on pr
27 xes further showed two distinct folds of the helix 6-7 region, classified as "open" and "closed", whi
28 two homologous copies of a six-transmembrane-helix (6-TM) domain, which has no sequence homology to t
29  of the acceptor arm of deacylated tRNA with helix 68 of 23S rRNA.
30               Nmd3 and Lsg1 together embrace helix 69 of the B2a intersubunit bridge, inducing base f
31 ere, we identify a structural element, alpha-helix-7, in human Argonaute2 (Ago2) that is required for
32 ecognition of specific, structured RNAs like Helix 70.
33 s the helix-loop transition in transmembrane helix 8, which likely forms the structural basis for CFT
34 UT1 variant in which we substituted membrane helix 9 with the equivalent GLUT3 sequence.
35 on RTA and makes primary contacts with alpha-helix A (residues 18-32), alpha-helix F (182-194), as we
36 haped substrate pocket, formed from an alpha-helix, a 310 helix, and a recently evolved tri-proline l
37                       Instead of a canonical helix, a noncanonical herringbone helix is formed.
38 ngineered TGF-beta monomer, lacking the heel helix, a structural motif essential for binding the TGF-
39 he Swellix program presented here combines a helix abstraction with a combinatorial approach to the R
40  bind membrane and form an amphipathic alpha-helix (AH).
41 t mutations in loop L1c-FlapI, loop L6c, and helix alpha1c of the RFK module (positions K202, E203, F
42         Our data show that the two A3H alpha-helixes alpha3 and alpha4 represent the Vif-binding site
43              Multiple residues within the S1 helix also play an important role in fine-tuning the vol
44 hPg residues occupied opposite faces of this helix, an arrangement that minimized steric clashing of
45 g events in biogenesis is the formation of a helix, an elementary structure that is ubiquitously pres
46 is concentrated in regions between the alpha-helix and beta-sheet domains.
47  polycrystalline material in which the alpha-helix and beta-sheet regions of the protein are similar
48  Vps4 subunit to join the growing end of the helix and engage the substrate, while hydrolysis and rel
49 s bound at the channel-periphery near the M4 helix and exerts a long-range allosteric effect on the p
50 t degron, Deg1, also contains an amphipathic helix and exhibits 42% amino acid similarity with SM N10
51 e demonstrate that targeted helix-(pi-sheet)-helix and helix-(pi-sheet)-coil assemblies occur without
52 in intercalates between turns of the dynamin helix and impairs fission by preventing trans interactio
53                                    The alpha-helix and random coil contents of the 600 MPa treated sa
54 for the first time, both the helicity of the helix and the form of the herringbone.
55 te pocket, formed from an alpha-helix, a 310 helix, and a recently evolved tri-proline loop.
56 comprising six transmembrane helices, a pore helix, and a selectivity filter.
57  the converter, the SH1-SH2 helix, the relay helix, and the lever, abolishes nonmuscle myosin-2 speci
58 rate 2 SMS excitation in transmural myofiber helix angle, mean diffusivity (mean +/- standard deviati
59 ed in the monomeric state but forms an alpha-helix approximately 70 residues long in the self-associa
60 ed and shown to form well-defined helix-turn-helix architectures in which helical and sheet subcompon
61 nce-defined helix-sheet-coil and helix-sheet-helix architectures, are Nature-inspired synthetic mimic
62 nstructured in isolation but tends to form a helix as evidenced by CD and NMR studies.
63 nd conformation, instead of forming an alpha-helix as observed in the previously solved structure of
64 D IR spectroscopy, parallel and antiparallel helix associations were identified by vibrational coupli
65 anionic lipid membranes using an amphipathic helix at its unique N-terminus.
66  that covers one full turn of the nucleosome helix at seven different SHLs, and that the position of
67                                          The helix at the C-terminus binds to the well-known p53-bind
68 electrostatic interactions near the Cbeta H3 helix at the membrane-proximal face of the TCR, a region
69 es and show that the pore is most probably a helix barrel that contains eight D4 peptides arranged in
70                                   Such alpha-helix barrels engineered from peptides could find applic
71 linearly with the G:C content of the hairpin helix, being 50% longer for hairpins with only A:T base
72 TR structure reveals a previously unresolved helix belonging to the R domain docked inside the intrac
73 s (PIFs) are members of the basic helix-loop-helix (bHLH) family of transcription factors in Arabidop
74 e transcription factor (TF) basic/Helix-Loop-Helix (bHLH) is important for plant growth, development,
75        We hypothesized that basic helix-loop-helix (bHLH) MIST1 (BHLHA15) is a "scaling factor" that
76 known as ITF2 or E2-2) is a basic helix-loop-helix (bHLH) protein associated with Pitt-Hopkins syndro
77 n anther-specific predicted basic helix-loop-helix (bHLH) transcription factor required for tapetal d
78 ns in lin-22, a Hes-related basic helix-loop-helix (bHLH) transcription factor, increase seam cell nu
79           This includes the basic helix-loop-helix (bHLH) transcription factors SPEECHLESS (SPCH), MU
80 ential up-regulation of two basic helix-loop-helix (bHLH) transcription factors with predicted effect
81 enile hormone receptor is a basic helix-loop-helix (bHLH), Per-Arnt-Sim (PAS) domain protein, a novel
82 e maturation protein, which, with just a six-helix bundle and a six-stranded beta-sheet, forms a geno
83 rom the C112R substitution in the N-terminal helix bundle and likely relate to a reduced ability of a
84 wo interhelical loops of the C-terminal four-helix bundle appear to penetrate the membrane bilayer, s
85 a FPPase and CPPase are located within a six-helix bundle containing amino acids 53 to 241.
86 y replacing the loops and helices of the six-helix bundle from enzyme with those from the other.
87 r to Polalpha, p261C of Pol contains a three-helix bundle in the middle and zinc-binding modules on e
88 o heptad-repeat regions refold to form a six-helix bundle structure that can be specifically targeted
89  revealed the complete structure of the four-helix bundle that forms the C-terminal domain.
90 nds to model the formation of the SNARE four-helix bundle that mediates synaptic vesicle fusion and u
91 ported water-soluble self-assembled foldamer helix bundle to encapsulate simple guest molecules withi
92 on replacement of the first helix in the six-helix bundle.
93 e distinct conformational changes within the helix bundle.
94 he FAM3C proteins do not form classical four-helix-bundle structures as was initially predicted.
95  of WhiB1 reveals that Wbl proteins are four-helix bundles with a core of three alpha-helices held to
96 e fifth subunit approximately continues this helix but appears to be dissociating.
97   In contrast, mutants lacking the TAD alpha-helix but retaining the most distal C-terminal residues
98 s in K2hPg Further, the adoption of an alpha-helix by VKK38 upon binding to K2hPg sterically optimize
99 tonated Ex moves upward, out of the positive helix cage.
100 ructure of StnA can be described as an alpha-helix cap domain on top of a common alpha/beta hydrolase
101           In the latter, the slope along the helix changes its sign at least twice per turn.
102 fold and the alpha2 helices form a tight two-helix coiled-coil.
103 we have developed porphyrin-peptoid (pigment-helix) conjugates (PPCs) that can modulate the donor-acc
104 al domain and an incipient amphipathic alpha-helix contained within it.
105 etween these potassium and water sites and a helix controlling the cytoplasmic gate of KdpA is linked
106 trate, while hydrolysis and release promotes helix disassembly and substrate release at the lagging e
107  in the A. thaliana kinome found that alphaC helix disorder may be a common feature of plant kinases.
108                               Importantly, a helix-disrupting mutation of W50R into residues 44-65 re
109 epair (BER) recognizes and repairs minimally helix-distorting DNA base lesions induced by both endoge
110 proteins share the Forkhead domain, a winged-helix DNA binding module, which is conserved among eukar
111 rial outer membrane via its N-terminal alpha helix domain and hosts a redox-active [2Fe-2S] cluster i
112 egion consists of a zinc domain and a winged helix domain and plays an important role in enzyme activ
113  domain near Pol I wall or the tandem winged helix domain of A49 at a partially overlapping location.
114       It contains one long, imperfect double helix (domain I), one branched domain (domain II) contai
115 ke domains forming one layer, and the winged-helix domains (WHDs) forming a top layer.
116 raphy, we show that Cdt1 contains two winged-helix domains in the C-terminal half of the protein and
117 que secondary structure that we term an "eta-helix" due to its repeating turns, which are highly remi
118 ation, AU/GU internal loop closure and AU/GU helix end parameters were particularly important.
119 s with alpha-helix A (residues 18-32), alpha-helix F (182-194), as well as the F-G loop.
120 fferences that alter the conformation of the helix F through helix G region in the upper portion of t
121 of At2g44920 as a representative of the beta-helix family to determine if it had exceptional global s
122 ion factors, members of the basic helix-loop-helix family, play crucial roles in mesoderm development
123 rties of mutations within an overlooked hERG helix, finding important contributions to channel functi
124 ructure immediately adjacent to the SecA two-helix finger subdomain before channel entry.
125  selectivity, which correlates strongly with helix folding, the system we report here is also highly
126 210 on the adjacent subunit's backbone alpha-helix form salt bridges in hexamers and pentamers.
127 ally, the N- and C-terminal halves of the TM helix form trimeric cores of opposite nature (hydrophobi
128 ngaged on cellulose, as models predict alpha-helix formation and decreased cellulose interaction for
129          Thus, reversible alphaS amphipathic helix formation and dynamic multimerization regulate a n
130 nd on the other hand, they can promote alpha-helix formation in certain peptides.
131  an important role in the zipper-like triple-helix formation in collagen.
132 , without any signs of intramolecular triple helix formation or fiber-fiber aggregation.
133 rwent coupled folding and binding with alpha-helix formation upon interaction with RCD1, whereas pept
134 esistant to conformational collapse or alpha-helix formation upon the addition of the osmolyte trimet
135 cle binding via membrane-induced amphipathic helix formation, and '3K' further enhances this effect.
136 oupling between membrane partitioning, alpha-helix formation, and electrostatic repulsions between ac
137 onds is the rate-limiting step during triple-helix formation.
138 s (GPCRs) have evolved a seven-transmembrane helix framework that is responsive to a wide range of ex
139          Our results show that the short 310-helix from D580 to S584 is critical for proper biogenesi
140 domains induces protection of the Nef alphaB-helix from deuterium uptake, consistent with a role for
141 gest that the formation of an extended alpha-helix from the disordered carboxy-terminal region of nuc
142 lter the conformation of the helix F through helix G region in the upper portion of the cavity and io
143 to a transient unfolding and dissociation of helix H that becomes more prominent at higher temperatur
144 Polymerization assays using Lmod2 mutants of helix h1 and the WH2 domain support this conclusion.
145 rms were observed on the heme-proximal side (helix H5), at the dimerization interface (helices H6 and
146 haracterize the substrate preferences of the helix-hairpin-helix (HhH) domains of XPF and ERCC-XPF an
147 conformational transitions in the C-terminal helix have specific functional involvements in PtdIns tr
148 ubiquitination-resistance were positioned at helix-helix interfaces, likely preventing the hepcidin-i
149 a tetratricopeptide-repeat (TPR), helix-turn-helix (HH), and U-box domain.
150 e substrate preferences of the helix-hairpin-helix (HhH) domains of XPF and ERCC-XPF and show that th
151        Cyanobacteria possess a family of one-helix high light-inducible proteins (Hlips) that are hom
152    Here, we identify a network of helix-loop-helix (HLH) transcriptional regulators controlled by MYT
153 x/loop regions, as well as of the C-terminal helix; (iii) the energy barrier of phospholipid extracti
154 obe cooperate to recognize a mixed alpha/310 helix in AKAP79.
155 at fibrillar exon1 has a partly mobile alpha-helix in its aggregation-accelerating N terminus, and se
156 ults support a model whereby the amphipathic helix in SM N100 attaches reversibly to the ER membrane
157 ed a deletion mutant lacking only this alpha-helix in stable cell lines and Xenopus laevis photorecep
158   Furthermore, we showed that an amphipathic helix in the C-terminal cytosolic tail of RHD3 has a mem
159 res of these three factors revealed an alpha-helix in the C-terminal inhibitory domain that packs aga
160 ties were lost upon replacement of the first helix in the six-helix bundle.
161 connecting helices, as well as the short 310 helix initiating the CTD.
162  G530 stabilizes the cognate codon-anticodon helix, initiating step-wise 'latching' of the decoding c
163 regulating signal sequence and transmembrane helix insertion in a substrate-dependent manner.
164 mall molecule stabilizes a mobile C-terminal helix inside a hydrophobic crevice of NCS-1 to impede Ri
165 ecific factors such as Cwc25 lock the branch helix into position for nucleophilic attack of the branc
166 due volume at the Phe position in the alpha1-helix is critical for alphaLbeta2 activation because tri
167 ding on cholesterol levels; with excess, the helix is ejected and unravels, exposing a hydrophobic pa
168  canonical helix, a noncanonical herringbone helix is formed.
169                       For example, a central helix is more frequently populated within the A2T-bound
170  the cleft closes, and the amphipathic alpha-helix is released to bind to the carrier domain via its
171 econdary structure with a low content of PII helix is remarkably efficient at promoting calcium adsor
172                                         This helix is required for association with actin as truncati
173                                     The FtsL helix is thus a candidate for acting as a potential mech
174 y residues in the S5, S6, and the first pore helix; isoflurane competitively disrupts A-967079 antago
175 l parameters of adjacent rungs in the triple-helix ladder and developed statistical potentials by ext
176 cription factor (MITF) is a basic helix-loop-helix leucine zipper (bHLH-Zip) DNA-binding protein.
177 ein, Gp5.7, which adopts a winged helix-turn-helix-like structure and specifically represses transcri
178  CFTR from all other ABC transporters is the helix-loop transition in transmembrane helix 8, which li
179 TING FACTORs (PIFs) are members of the basic helix-loop-helix (bHLH) family of transcription factors
180          The transcription factor (TF) basic/Helix-Loop-Helix (bHLH) is important for plant growth, d
181                   We hypothesized that basic helix-loop-helix (bHLH) MIST1 (BHLHA15) is a "scaling fa
182 (TCF4 also known as ITF2 or E2-2) is a basic helix-loop-helix (bHLH) protein associated with Pitt-Hop
183  encoding an anther-specific predicted basic helix-loop-helix (bHLH) transcription factor required fo
184 hat mutations in lin-22, a Hes-related basic helix-loop-helix (bHLH) transcription factor, increase s
185                      This includes the basic helix-loop-helix (bHLH) transcription factors SPEECHLESS
186  the differential up-regulation of two basic helix-loop-helix (bHLH) transcription factors with predi
187  insect juvenile hormone receptor is a basic helix-loop-helix (bHLH), Per-Arnt-Sim (PAS) domain prote
188               Here, we identify a network of helix-loop-helix (HLH) transcriptional regulators contro
189                The spermatogenesis/oogenesis helix-loop-helix (SOHLH) proteins SOHLH1 and SOHLH2 play
190  transcription factors, members of the basic helix-loop-helix family, play crucial roles in mesoderm
191 almia transcription factor (MITF) is a basic helix-loop-helix leucine zipper (bHLH-Zip) DNA-binding p
192                                    The basic helix-loop-helix PAS domain (bHLH-PAS) transcription fac
193  HAIR DEFECTIVE-SIX LIKE (RSL) class I basic helix-loop-helix proteins are expressed in future root h
194 roaches, we discovered that the Id family of helix-loop-helix proteins is both necessary and sufficie
195 nd 5' RACE identified the prooncogenic basic helix-loop-helix transcription factor ID1 as an IRE1alph
196 p1 Inhibitor of differentiation 1 (Id1) is a helix-loop-helix transcription factor that plays an impo
197 PK3 and MPK6 can phosphorylate ICE1, a basic-helix-loop-helix transcription factor that regulates the
198                        Homeodomain and basic helix-loop-helix transcription factors are required for
199 is accompanied by loss of flexibility of two helix/loop regions, as well as of the C-terminal helix;
200            The key finding in the DNA double helix model is the specific pairing or binding between n
201 r an interesting semblance to the DNA double helix model.
202  a helical hairpin, and bipartite helix-turn-helix motif.
203  at least a factor of 60, confirming that TM helix motions are linked to the citrate-binding event.
204 ges that lead to asynchronous pore-lining M2 helix movements.
205 in the protein where the intersection of two helix N-termini creates a region with a strong, localize
206 th POTRA2 containing an additional elongated helix not observed previously in other POTRA domains.
207 ithin the hydrophobic half of the stabilized helix not only reversed the strong membrane interaction
208 lly conserved bulged uridine (U51) in the P4 helix of circularly permuted Bacillus subtilis P RNA wit
209 dulates the rate of Ziploc-ing of the triple helix of collagen in the rER.
210 Delta60) suggested that an 'accessory' alpha-helix of Complexin-I inhibits release by inserting into
211                                          The helix of FtsB is interrupted between the transmembrane a
212 olved for any linear peptoid, revealed a PPI helix of great regularity despite the presence of only 5
213 cysteine (Cys195) in the third transmembrane helix of Orai1.
214 talytically important interactions of the P4 helix of P RNA with metal ions, demonstrating that the b
215 substitutions, locating to the transmembrane helix of TatB that restored transport activity to Tat si
216             We also show that the C-terminal helix of the bHLH domain is involved in intermolecular i
217 ecular interactions with the DNA-recognition helix of the ETS domain to mediate autoinhibition.
218 main of one molecule bound to the C-terminal helix of the neighboring D1 domain.
219 lular half outward to accommodate the alpha5-helix of the Ras-like domain of Gs.
220     The three-way junction and the P1 switch helix of the two apo conformers are notably different fr
221 the U2AF-homology motif (UHM) and the alpha6 helix of U2AF35, and was fine-tuned by exon Ab/3 variant
222  last 16 CCD residues, composing an "overlap helix" (OH), have been crystallized in two mutually excl
223 h helix rotations and movements toward a two-helix packing mode.
224 lated DNA local parameters, step parameters, helix parameters, and major/minor groove widths to exami
225 docked conformation and the preceding alpha6 helix partially melted.
226                         The basic helix-loop-helix PAS domain (bHLH-PAS) transcription factor CLOCK:B
227 the robust autophagy activity of the Kalpha2-helix peptide, the present study showed that treatment w
228  antiviral activities of synthesized Kalpha2-helix peptide, which was derived from the viral FLICE-li
229 ate that targeted helix-(pi-sheet)-helix and helix-(pi-sheet)-coil assemblies occur without compromis
230                 We demonstrate that targeted helix-(pi-sheet)-helix and helix-(pi-sheet)-coil assembl
231 ane proteins with a single membrane-spanning helix play a plethora of vital roles in the cellular pro
232 SECM/optical microscope, generating a double helix point spread function at the image plane, which al
233 ing module, a membrane-inducible amphipathic helix present in a previously undescribed location in At
234 s steps involving unwinding-rewinding of the helix proceeded over the course of days.
235 as previously been employed to measure alpha-helix propensities among proteinogenic alpha-amino acid
236 rrounded by IDRs, individual intrinsic alpha-helix propensities varied as shown by CD spectroscopy.
237 d in nonphotochemical quenching, and the one-helix proteins and their cyanobacterial homologs designa
238 TIVE-SIX LIKE (RSL) class I basic helix-loop-helix proteins are expressed in future root hair cells (
239  discovered that the Id family of helix-loop-helix proteins is both necessary and sufficient to direc
240 dulating the position of the DNA recognition helix region relative to its major groove.
241 esulting in a rearrangement of the substrate helix register into a so-called "shifted" conformation t
242 ike movement of beta6-alpha7 loop and alpha7-helix, required for high-affinity ligand binding.
243 ge in a specific interaction with post-relay helix residue Glu-469, which affects the mechanics of th
244                                         Pore helix rotation by STIM1 also explains the dynamic coupli
245 onal amplitudes of the Tsr HAMP coupled with helix rotations and movements toward a two-helix packing
246 dues in pore helix 1, helices S5 and S6, and helix S6 of a neighbouring subunit, form a hydrophobic c
247 n to Survivin and Borealin, the single alpha-helix (SAH) domain of INCENP supports CPC localization t
248 ha1 and alpha2 helices are consistent with a helix scissors motion or a gearbox rotational model of H
249 inding pocket in mdm2 whereas the N-terminal helix serves as an affinity enhancer.
250 rgeted assemblies, a mix of sequence-defined helix-sheet-coil and helix-sheet-helix architectures, ar
251 mix of sequence-defined helix-sheet-coil and helix-sheet-helix architectures, are Nature-inspired syn
252  transcription are sufficient to give M2-seq helix signatures; these signals were previously overlook
253 amaterial consisting of interconnected metal helix slat structures with four-fold symmetry, which exh
254     The spermatogenesis/oogenesis helix-loop-helix (SOHLH) proteins SOHLH1 and SOHLH2 play important
255                                              Helix stabilities are relatively low, 4 kcal/mol to 5 kc
256    Studies of F103 in the hinge of the inner helix suggest an important role for its bulky sidechain
257 mely Kite dimers (Kleisin interacting winged-helix tandem elements), interact with Smc-kleisin rings
258  secondary structural element is one turn of helix that binds the central portion of the CRM1 groove.
259 occurs at the N-terminus and the first alpha-helix that connects the HlyIIC domain to the HlyII-core
260 e six VAT subunits to constrict into a tight helix that grips an 80 A stretch of unfolded protein.
261 e the extended loop prior to the penultimate helix, the extended Omega-loop, and a beta-hairpin turn
262 ctions connecting the converter, the SH1-SH2 helix, the relay helix, and the lever, abolishes nonmusc
263 e (EC portion) to HL1 and to the neighboring helix TM2.
264 omote the pentapeptides transform from alpha-helix to beta-sheet conformation.
265 ositively charged residues in the C-terminal helix to engage in DNA binding, triggering a major repro
266  helix-turn-helix (wHTH) motifs use an alpha helix to read the base sequence in the major groove whil
267 ain (LBD) of hPXR, interacting with the AF-2 helix to stabilize the LBD for coactivator binding.
268  target RNA and extends a newly-formed alpha helix to the distal loop where it forms protein interact
269 identified the prooncogenic basic helix-loop-helix transcription factor ID1 as an IRE1alpha RNase tar
270 r of differentiation 1 (Id1) is a helix-loop-helix transcription factor that plays an important role
271 6 can phosphorylate ICE1, a basic-helix-loop-helix transcription factor that regulates the expression
272             Homeodomain and basic helix-loop-helix transcription factors are required for retinogenes
273  The functionally relevant random-coil-alpha-helix transition associated with Ca(2+) uptake that invo
274 duced Circulating LncRNA) partakes in triple helix (triplex) formation, is transiently elevated follo
275 r emission, while the closure of the labeled helix turn reduces this emission.
276                                          The helix, turn, and beta-strand motifs of biopolymer folded
277 onsists of a tetratricopeptide-repeat (TPR), helix-turn-helix (HH), and U-box domain.
278                              TFs with winged helix-turn-helix (wHTH) motifs use an alpha helix to rea
279 n synthesized and shown to form well-defined helix-turn-helix architectures in which helical and shee
280 pin domain, a helical hairpin, and bipartite helix-turn-helix motif.
281 kDa T7 protein, Gp5.7, which adopts a winged helix-turn-helix-like structure and specifically repress
282 s suggest that a likely mechanism for triple helix unfolding is intermolecular shearing of collagen a
283  analysis, we demonstrate that transmembrane helix VI, extracellular loop 3 and the HD play a central
284               A serine residue on the DIV S2 helix was found to be sufficient to explain Pre1a's pote
285                         Although the Bik BH3 helix was sufficient to enrich for ER-Bak and elicit ER
286                  In the canonical DNA double helix, Watson-Crick (WC) base pairs (bps) exist in dynam
287  exposed conformation stacked within the DNA helix, where it effectively blocks nucleotide incorporat
288 sing site is located on the face of the beta-helix whereas the C-terminal domain is likely involved i
289 to GPP, until replacement of the final alpha-helix, whereupon cyclopropanation and branching activity
290 ructurally blocked by the HECT domain alpha1-helix, which further undergoes ubiquitylation on a conse
291 sis suggests that it can form an amphipathic helix, which is ideal for lipid membrane interaction.
292 des extra bulk, probably in the form of a pi-helix, which is required for stringent gating and tight
293 ith an antiparallel motion of the C-terminal helix, which may alter the native-state structural ensem
294                    Four Vps4 subunits form a helix whose interfaces are consistent with ATP binding,
295                   TFs with winged helix-turn-helix (wHTH) motifs use an alpha helix to read the base
296 es possess an unstructured beta-domain and C-helix with the rest of the alpha-domain remaining native
297 d circular dichroism revealed an amphipathic helix within this 12-residue region.
298             Furthermore, the incipient alpha-helix (within the purified soluble C terminus) partition
299  1, can spontaneously assemble into a double helix without the need for a covalently connected linear
300 nucleic acid-binding domains for left-handed helix (Z-form) and receptor-interacting protein homotypi

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