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1 d this transcription factor, flowering basic helix-loop-helix 1 (FBH1) that binds in vivo to the prom
2 at protein and transcript levels of nescient helix loop helix 2 (NHLH2) and the prohormone convertase
3 ow that the Caenorhabditis elegans E-protein helix-loop-helix-2 (HLH-2) functions as a homodimer in d
7 tor (ARNT) subunit, which dimerize via basic helix-loop-helix and PAS domains, and recruit coactivato
8 we have found that the previously identified helix-loop-helix and Ufd2-box domains in human Act1 have
9 3), bZIP (basic-leucine zipper), bHLH (basic helix-loop-helix) and SBP (SQUAMOSA promoter binding pro
10 cription factors composed of R2R3 MYB, basic helix-loop-helix, and WD40 proteins that activate the pr
12 ion and degradation of phy-interacting basic Helix Loop Helix (bHLH) transcription factors (PIFs), su
13 om Arabidopsis thaliana and associated basic helix-loop-helix (bHLH) and MYB transcription factors ac
14 both the anthocyanin pathway genes and basic-helix-loop-helix (bHLH) ANTHOCYANIN1 (AN1), itself an es
15 anced mRNA and protein expression of a basic helix-loop-helix (bHLH) class myogenic determination fac
16 ificities of 19 Caenorhabditis elegans basic helix-loop-helix (bHLH) dimers using protein binding mic
17 ter 1 is actually a membrane-localized basic helix-loop-helix (bHLH) DNA-binding transcription factor
18 other species' HIF-1, HdHIF-1 has one basic helix-loop-helix (bHLH) domain and two Per-Arnt-Sim (PAS
19 3-MYB regulator C1 cooperates with the basic helix-loop-helix (bHLH) factor R to activate the express
21 proneural transcription factors of the basic helix-loop-helix (bHLH) family are required to commit ce
22 TING FACTORs (PIFs) are members of the basic helix-loop-helix (bHLH) family of transcription factors
26 ntified as homologs of the subgroup lb basic helix-loop-helix (bHLH) genes that are known to regulate
29 DNA as a homo- or heterodimer via its basic helix-loop-helix (bHLH) motif, little is known about the
30 We show here that the Ascl1 and Neurog basic helix-loop-helix (bHLH) proneural factors are expressed
31 iation is largely under the control of basic Helix-Loop-Helix (bHLH) proneural transcription factors
32 (TCF4 also known as ITF2 or E2-2) is a basic helix-loop-helix (bHLH) protein associated with Pitt-Hop
35 l characterization of a plant-specific basic helix-loop-helix (bHLH) protein, FEHLSTART (FST), a defe
36 ochrome Interacting Factor 1 (PIF1), a basic helix-loop-helix (bHLH) protein, functions as a negative
37 eracts with and inhibits a DNA binding basic helix-loop-helix (bHLH) protein, HBI1, in Arabidopsis th
42 h proneural activator (P) proteins and basic helix-loop-helix (bHLH) repressor (R) factors (a "P+R" r
43 In the dorsal spinal cord, Ptf1a, a basic helix-loop-helix (bHLH) transcription activator, maintai
48 emonstrate that mice deficient for the basic helix-loop-helix (bHLH) transcription factor Bhlhe40 (Bh
49 e, we identified a jasmonate-regulated basic helix-loop-helix (bHLH) transcription factor from clade
51 f SPARC, as well as the Notch effector basic helix-loop-helix (bHLH) transcription factor hairy and e
53 atory cells in both sexes requires the basic-helix-loop-helix (bHLH) transcription factor HLH-2, the
55 gibberellin, that inhibit the atypical basic helix-loop-helix (bHLH) transcription factor INCREASED L
60 encoding an anther-specific predicted basic helix-loop-helix (bHLH) transcription factor required fo
61 thaliana) require the function of the basic helix-loop-helix (bHLH) transcription factor SPEECHLESS
63 ns of TWIST1, which encodes a class II basic helix-loop-helix (bHLH) transcription factor, and causes
64 arise from progenitors expressing the basic helix-loop-helix (bHLH) transcription factor, Atoh7, whi
65 hat mutations in lin-22, a Hes-related basic helix-loop-helix (bHLH) transcription factor, increase s
66 gene male sterility32 (ms32) encodes a basic helix-loop-helix (bHLH) transcription factor, which func
67 f achaete-scute homologue 2 (Ascl2)--a basic helix-loop-helix (bHLH) transcription factor--is selecti
68 d three genes (NtMYC2a, b, c) encoding basic helix-loop-helix (bHLH) transcription factors (TFs) whos
69 characterization of two genes encoding basic-helix-loop-helix (bHLH) transcription factors (TFs), NtM
70 es oligodendrocyte development through basic-helix-loop-helix (bHLH) transcription factors and promot
72 ential activation of master regulatory basic-helix-loop-helix (bHLH) transcription factors controls t
73 al and temporal expression of specific basic-helix-loop-helix (bHLH) transcription factors defines ma
78 nds upon the function of the proneural basic helix-loop-helix (bHLH) transcription factors NEUROG1 an
79 find that expression of the proneural basic helix-loop-helix (bHLH) transcription factors Neurog2 or
80 , by controlling the activity of three basic-helix-loop-helix (bHLH) transcription factors of the PHY
84 inin antagonized the ability of neural basic helix-loop-helix (bHLH) transcription factors to activat
86 the differential up-regulation of two basic helix-loop-helix (bHLH) transcription factors with predi
87 ated at least partly by regulating two basic helix-loop-helix (bHLH) transcription factors, Neurog1 a
88 Here we report interactions between basic helix-loop-helix (bHLH) transcriptional activators and t
89 e expression of BARREN STALK1 (BA1), a basic helix-loop-helix (bHLH) transcriptional regulator necess
91 ecific genes Sohlh1 and Sohlh2, encode basic helix-loop-helix (bHLH) transcriptional regulators that
92 the core of the network are TFs of the basic helix-loop-helix (bHLH), nuclear factor I (NFI), SOX, an
93 insect juvenile hormone receptor is a basic helix-loop-helix (bHLH), Per-Arnt-Sim (PAS) domain prote
95 lear translocator (ARNT) belong to the basic helix-loop-helix (bHLH)-PER-ARNT-SIM (PAS) family of tra
96 of ARNT itself is modulated by another basic helix-loop-helix (bHLH)-Per-ARNT-SIM (PAS) protein, the
98 AhR), a ligand-activated member of the basic helix-loop-helix (bHLH)/PER-ARNT-SIM (PAS) transcription
100 onal activation by MYB134 and that the basic helix-loop-helix-binding motif of MYB182 was essential f
101 ion factor families (zinc finger GATA, basic helix-loop-helix, BTF3/NAC [for basic transcription fact
103 ranscripts of a MYB PA activator and a basic helix-loop-helix cofactor was observed in MYB182-overexp
105 mapped the interaction interface to the MYC helix-loop-helix domain and a novel 15-residue MYC-bindi
106 interact on the MIC-1 promoter via the basic helix-loop-helix domain in DEC1 and the tetramerization
111 ionally and computationally designed site II helix-loop-helix epitope-scaffold vaccines distinguished
115 e the roles of Phytochrome-Interacting basic helix-loop-helix Factors, PIF1, 3, 4, and 5, in relaying
116 re members of the Arabidopsis thaliana basic helix-loop-helix family of transcriptional regulators th
117 encodes a transcription factor of the basic/helix-loop-helix family sufficient to cause hyperplasia.
118 microarray analyses and identified the basic helix-loop-helix family transcription factor Bhlhe40 as
119 the Os07g11020 or Rc locus encoding a basic helix-loop-helix family transcription factor by intragen
120 e-specific transcription factor of the basic helix-loop-helix family, and c-Kit, a tyrosine kinase re
121 transcription factors, members of the basic helix-loop-helix family, play crucial roles in mesoderm
122 inducible transcription factors of the basic helix-loop-helix family, TRITERPENE SAPONIN BIOSYNTHESIS
123 that the compensatory mutations increase the helix-loop-helix flexibility, allowing rescue of the cor
124 ily of plant defense peptides that share the helix-loop-helix fold stabilized by two disulfide bridge
127 l structure of AS8 was solved, revealing the helix-loop-helix geometry of the unique AS8 insertion re
128 ocator (ARNT) protein, occurring through the Helix-Loop-Helix (HLH) and PER-ARNT-SIM (PAS) domains, i
129 of the paclobutrazol-resistant (PRE) family helix-loop-helix (HLH) factors, which promote cell elong
137 ppress the expression of a common downstream helix-loop-helix (HLH)/bHLH network, thus forming an inc
138 ining the structure of MerFt, the 60-residue helix-loop-helix integral membrane core of the 81-residu
139 in gene-binding protein (VBP)] and two basic helix-loop-helix leucine zipper (B-HLH-ZIP) [USF (upstre
140 ology box II (MBII) and the C-terminal basic helix-loop-helix leucine zipper (bHLH-LZ) domains of the
141 almia transcription factor (MITF) is a basic helix-loop-helix leucine zipper (bHLH-Zip) DNA-binding p
142 obligate transcription partner Mlx are basic helix-loop-helix leucine zipper (bHLHZip) transcription
143 iated transcription factor (MITF) is a basic helix-loop-helix leucine zipper protein that plays major
144 he RTG pathway relies on Rtg1 and Rtg3 basic helix-loop-helix leucine Zipper transcription factors.
145 eport here for the first time that the basic helix-loop-helix-leucine-zip transcription factor upstre
147 -IBH1-HBI1 tripartite helix-loop-helix/basic helix-loop-helix module is part of a central transcripti
148 potent neutralizing antibody that binds to a helix-loop-helix motif in the RSV fusion glycoprotein.
150 ture of gp6 reveals a dimeric protein with a helix-loop-helix motif similar to that of bacteriophage
151 c core domain and C-terminal domain adopts a helix-loop-helix motif that is similar to the correspond
152 studies, Mdv1 binds Fis1 through a U-shaped helix-loop-helix motif, and dimerization of the Mdv1-Fis
153 ) of the coat protein through its C-terminal helix-loop-helix motif, as well as unexpected interactio
155 expectedly, the predicted leucine zipper and helix-loop-helix motifs do not form these structures but
159 containing putative binding sites for basic/helix-loop-helix, MYB, and BZIP transcription factors.
161 anscription factor that belongs to the basic helix-loop-helix PAS (Per-Arnt-Sim homology domain) fami
163 criptional activator consisting of two basic helix-loop-helix PER-ARNT-SIM (bHLH-PAS) domain protein
164 anscription factor and a member of the basic helix-loop-helix PER/ARNT/SIM family of chemosensors and
165 ins NPAS1 and NPAS3 are members of the basic helix-loop-helix-PER-ARNT-SIM (bHLH-PAS) family, and the
167 racting factoR3-like5, which encodes a basic helix-loop-helix protein coordinating hormone responses
172 negative heterodimer partners for the basic-helix-loop-helix protein family and as such contribute t
174 tal muscle that expresses the myogenic basic helix-loop-helix protein MyoD but fails to undergo termi
175 tional 26S proteasome and involves the basic helix-loop-helix protein SPATULA as a key component.
176 Atonal homolog1 (Atoh1) encodes a basic helix-loop-helix protein that is the first transcription
177 atenin through an interaction with the basic helix-loop-helix protein upstream stimulatory transcript
178 idopsis (Arabidopsis thaliana) FAMA, a basic helix-loop-helix protein whose actions during the final
180 HAIR DEFECTIVE-SIX LIKE (RSL) class I basic helix-loop-helix proteins are expressed in future root h
181 roaches, we discovered that the Id family of helix-loop-helix proteins is both necessary and sufficie
182 e, we show that genes encoding the two basic helix-loop-helix proteins PpSMF1 (SPEECH, MUTE and FAMA-
185 pmental regulatory pathways that include the helix-loop-helix regulator hlh-2/daughterless and transc
186 a previously undescribed fold, consisting of helix-loop-helix repeats arranged into an overall cresce
189 is a well-characterized, approximately 24-aa helix-loop-helix structure on the RSV fusion (F) protein
190 omain of TbTRF, which folds into a canonical helix-loop-helix structure that is conserved to the Myb
194 iation via induction of GATA-4 and the basic helix-loop-helix TAL1 and that knockdown of both factors
197 C3 promoter and identified that twist basic helix-loop-helix transcription factor 1 (TWIST1) binds t
198 our data suggest TWIST1 (twist family basic helix-loop-helix transcription factor 1) and SSPN (sarco
199 em-cell regulator achaete-scute family basic helix-loop-helix transcription factor 2 (ASCL2), Wnt/bet
200 previous data suggested that the human basic helix-loop-helix transcription factor achaete-scute homo
202 Previously, we showed that DEC1, a basic helix-loop-helix transcription factor and a target of p5
203 tionally, we have identified Twist1, a basic helix-loop-helix transcription factor and a well-known E
207 present study we demonstrate that the basic helix-loop-helix transcription factor Atonal homolog 8 (
209 nce is provided that the BR-controlled basic helix-loop-helix transcription factor CESTA (CES) can co
213 tral regulator of this response is the basic helix-loop-helix transcription factor FER-LIKE IRON DEFI
214 homozygous frameshift mutation in the basic helix-loop-helix transcription factor gene ARNT2 (c.1373
215 stricting the expression domain of the basic helix-loop-helix transcription factor gene SPATULA.
219 nd 5' RACE identified the prooncogenic basic helix-loop-helix transcription factor ID1 as an IRE1alph
222 inhibitory interaction with Twist1, a basic helix-loop-helix transcription factor known to increase
224 iency-induced TRANSCRIPTION FACTOR1, a basic helix-loop-helix transcription factor necessary for indu
225 A role has been demonstrated for the basic helix-loop-helix transcription factor NeuroD1 in the pat
230 ME INTERACTING FACTOR3 (PIF3) is a key basic helix-loop-helix transcription factor of Arabidopsis tha
233 THAIR DEFECTIVE SIX-LIKE (RSL) class I basic helix-loop-helix transcription factor positively regulat
236 Previously, it has been shown that basic helix-loop-helix transcription factor Ptf1a is required
238 Previously we demonstrated that the basic helix-loop-helix transcription factor root hair defectiv
239 recruitment followed the loss from the basic helix-loop-helix transcription factor SPATULA (SPT) of a
240 tal lineage cells is controlled by the basic helix-loop-helix transcription factor SPEECHLESS (SPCH).
241 ed a progenitor, marked by the expression of helix-loop-helix transcription factor stem cell leukemia
242 itor of DNA-binding 2 (Id2) is an inhibitory helix-loop-helix transcription factor that is highly exp
243 p1 Inhibitor of differentiation 1 (Id1) is a helix-loop-helix transcription factor that plays an impo
244 Inhibitor of differentiation 1 (Id1) is a helix-loop-helix transcription factor that plays importa
247 PK3 and MPK6 can phosphorylate ICE1, a basic-helix-loop-helix transcription factor that regulates the
248 ICANCE STATEMENT The importance of the basic helix-loop-helix transcription factor transcription fact
251 few olfactory sensory neurons when the basic helix-loop-helix transcription factor, ASCL1 (previously
254 ouse and zebrafish illustrate that the basic-helix-loop-helix transcription factor, Hand2, is crucial
258 ly interacts with and phosphorylates a basic helix-loop-helix transcription factor, MYC2, and is phos
259 tral tegmental area that expresses the basic helix-loop-helix transcription factor, Neurogenic Differ
262 e expression of neurogenin 2 (Ngn2), a basic helix-loop-helix transcription factor, was significantly
263 scient helix-loop-helix-2 (NHLH2) is a basic helix-loop-helix transcription factor, which has been im
265 e) two-hybrid screening, we identified basic helix-loop-helix transcription factor05 (bHLH05) as an i
266 amined whether four of the subgroup Ib basic helix-loop-helix transcription factors (bHLH38, bHLH39,
267 ction screens identified three related basic helix-loop-helix transcription factors (MYC2, MYC3, and
269 omata formation is induced by a set of basic helix-loop-helix transcription factors and inhibited by
271 ve determined that the two Arabidopsis basic helix-loop-helix transcription factors bHLH25 and bHLH27
272 A) E3 ubiquitin ligase and a subset of basic helix-loop-helix transcription factors called phytochrom
273 NTR) is an oscillating gene regulated by the helix-loop-helix transcription factors CLOCK and BMAL1.
274 restriction of symplastic movement of basic helix-loop-helix transcription factors into neighboring
275 eprogramming that does not involve the basic helix-loop-helix transcription factors MYC2 and related
276 ctions between BTS and PYE-like (PYEL) basic helix-loop-helix transcription factors occur within the
278 ability of MYC2, MYC3, and MYC4, three basic helix-loop-helix transcription factors that additively c
279 New Gene (RING) domain, interacts with basic helix-loop-helix transcription factors that are capable
280 nt lacking MYC2, MYC3, and MYC4, three basic helix-loop-helix transcription factors that are known to
281 module is a set of "master regulator" basic helix-loop-helix transcription factors that regulate ind
284 cting factors (PIFs), a small group of basic helix-loop-helix transcription factors, repress photomor
285 pid phosphorylation and degradation of basic helix-loop-helix transcription factors, such as PHYTOCHR
286 of a family of antagonistically acting basic helix-loop-helix transcription factors, the PHYTOCHROME-
288 ID4, a dominant-negative inhibitor of basic helix-loop-helix transcription factors, up-regulated in
292 cell factor-1 (ABF-1), which encodes a basic helix-loop-helix transcriptional repressor, participates
295 hanges were seen in mRNA levels of conserved helix-loop-helix ubiquitous kinase, IRAK1, 2, TLR4, 9 an
296 strated that proinflammatory TLRs (conserved helix-loop-helix ubiquitous kinase, IRAK1, TLR1, TLR4, T
298 nd RNAi-based approaches and found the basic helix-loop-helix ZIP transcription factor AP4 to have an
299 eavage does not require the N-terminal basic helix-loop-helix zipper transcription factor domain, thu
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