ライフサイエンスコーパス: helix-turn-helix

1 r, a minor-groove binding alpha-helix, and a helix-turn-helix.

2 In detergent, the IFP forms helix-turn-helix and helix-turn-strand structures at pH

3 f individual residues within the DNA-binding helix-turn-helix and the winged region as well as within

4 sidue alpha-helix, a 34-residue cross-linked helix-turn-helix, and a 16-residue beta-hairpin) in the

5 The La motif adopts a winged helix-turn-helix architecture that has a highly conserve

6 membrane-mimetic environments, consists of a helix-turn-helix architecture that is independent of pH.

7 n synthesized and shown to form well-defined helix-turn-helix architectures in which helical and shee

8 ation domain, which adopts a similar stacked helix-turn-helix arrangement as its homologs GLD-1 (germ

9 Substitution of the helix-turn-helix capping motif (residues 9-35) of rabbit

10 The SpxR protein contains helix-turn-helix, CBS and HotDog domains implicated in b

11 , either of the ribbon-helix-helix or of the helix-turn-helix class; in other TAS, proteins containin

12 a close variant, T/SxxH, which initiates the helix-turn-helix conformation and presumably contributes

13 ation it appeared to adopt an intramolecular helix-turn-helix conformation.

14 ation motion during the export of nativelike helix-turn-helix conformations.

15 e provide evidence that RapLS20 binds to the helix-turn-helix-containing domain of RcoLS20 in vivo, p

16 ious Rossmann-type folds and between various helix-turn-helix-containing families.

17 The central part of the protein assumes a helix-turn-helix core domain with two well-defined alpha

18 ed-coil and a second, hitherto unidentified, helix-turn-helix dimerization interface at the C-termina

19 ereas the carboxy-terminal domain contains a helix turn helix DNA-binding motif.

20 No detectable helix-turn-helix DNA binding domain is associated with e

21 t two receiver domains, an OmpR-class winged helix-turn-helix DNA binding domain, and a histidine pho

22 eins, the C. jejuni ModE binds DNA through a helix-turn-helix DNA binding domain, but unlike other me

23 hereas dsDNA binding activity resides in the helix-turn-helix DNA binding domain.

24 esses characteristic autoinducer binding and helix-turn-helix DNA binding domains and shares a high l

25 ntral to the functions of Fis and involves a helix-turn-helix DNA binding motif located in the carbox

26 stitutions were generated in or near the Fis helix-turn-helix DNA binding motif, and the resulting pr

27 e structure reveals the presence of a winged-helix-turn-helix DNA binding motif, but the location of

28 the AsiA protomer, surprisingly, contains a helix-turn-helix DNA binding motif, predicting a potenti

29 To bind DNA, OhrR employs a chimeric winged helix-turn-helix DNA binding motif, which is composed of

30 fundamental building block of the widespread helix-turn-helix DNA binding motif.

31 1298 was identified that contains a putative helix-turn-helix DNA binding motif.

32 It forms a three-helix bundle containing a helix-turn-helix DNA binding motif.

33 ding (GAF) domain, and a bacterial AraC type helix-turn-helix DNA binding motif.

34 acid carboxy-terminal domain (CTD) with two helix-turn-helix DNA binding motifs and an approximately

35 o the two tandemly arranged homeodomain-like helix-turn-helix DNA binding motifs of centromere bindin

36 ate anti-sigma factor, MibW, and a potential helix-turn-helix DNA binding protein, MibR.

37 raC/XylS family of regulators, and RtsB is a helix-turn-helix DNA binding protein.

38 ng site, partially overlapping with a winged helix-turn-helix DNA binding site.

39 In Lrp-family proteins, an N-terminal helix-turn-helix DNA-binding and dimerizing domain is jo

40 iption factors that share a highly conserved helix-turn-helix DNA-binding domain and a less conserved

41 imeric protein containing a short N-terminal helix-turn-helix DNA-binding domain and a long C-termina

42 s58 and Cys60 from the alpha(3) helix of the helix-turn-helix DNA-binding domain and Cys7 and/or Cys1

43 largely accomplished via a highly conserved helix-turn-helix DNA-binding domain that is known as a h

44 N-terminal dimerization domain, a C-terminal helix-turn-helix DNA-binding domain, and a beta-strand l

45 al regulatory domain and a C-terminal winged helix-turn-helix DNA-binding domain, with phosphorylatio

46 d third helices (alpha 8 and alpha 9) form a helix-turn-helix DNA-binding domain.

47 riptional activator (PspR) with a C-terminal helix-turn-helix DNA-binding domain.

48 d proteins consisting of only the C-terminal helix-turn-helix DNA-binding domains of both proteins at

49 als an unexpected synaptic interface between helix-turn-helix DNA-binding domains that is also highli

50 ly of transcription factors and contains two helix-turn-helix DNA-binding domains, POU(HD) and POU(S)

51 een used as small molecule sensor coupled to helix-turn-helix DNA-binding domains.

52 The N-terminal region of RstR contains a helix-turn-helix DNA-binding element similar to the heli

53 -interaction domain, flanked by a C-terminal helix-turn-helix DNA-binding motif and a divergent N-ter

54 The N-terminal DNA-binding domain contains a helix-turn-helix DNA-binding motif and alteration of cer

55 hile the N-terminal domains contain a winged helix-turn-helix DNA-binding motif and are arranged arou

56 The protein contains a typical helix-turn-helix DNA-binding motif and can be classified

57 The first gene product (ORF1) has a putative helix-turn-helix DNA-binding motif and shows sequence si

58 The C-terminal domain has a classical helix-turn-helix DNA-binding motif that is located at op

59 Like Fur, DtxR contains a helix-turn-helix DNA-binding motif, recognizes a 19-bp i

60 of significant homology, which includes the helix-turn-helix DNA-binding motif, with the Escherichia

61 l domain, exposing a previously unrecognized helix-turn-helix DNA-binding motif.

62 etermine the functionality of four potential helix-turn-helix DNA-binding motifs (HTH1-HTH4) identifi

63 ions harboring a TFIIIA-type zinc finger and helix-turn-helix DNA-binding motifs.

64 (factor for inversion stimulation) family of helix-turn-helix DNA-binding proteins.

65 residues located both within and outside the helix-turn-helix DNA-binding region are critical.

66 posed of three domains: an N-terminal winged helix-turn-helix domain (WH), a GAF-like domain, and an

67 DNA revealed that SpoIIID does indeed have a helix-turn-helix domain and that it has a novel C-termin

68 The degenerate helix-turn-helix domain at the C-terminus of MCM exerts

69 models in which the recognition helix of the helix-turn-helix domain interacts with the major groove

70 conserved arginine residue within the winged helix-turn-helix domain is necessary for modulation of t

71 caused an amino acid change in the putative helix-turn-helix domain of MexL.

72 in is fused to a C-terminal MarR-like winged helix-turn-helix domain that is expected to be involved

73 is a highly conserved carboxy-terminal basic helix-turn-helix domain that is involved in dimerization

74 AbiEi has an N-terminal winged-helix-turn-helix domain that is required for repression

75 hat has a frameshift removing its C-terminal helix-turn-helix domain, grows very slowly and different

76 nucleases, are replaced by an unusual winged helix-turn-helix domain, where the "wing" is contributed

77 A binds DNA predominantly via its C-terminal helix-turn-helix domain, with direct binding of recognit

78 erved consensus motif (SQQQFSRYE) within the helix-turn-helix domain.

79 gulators and are predicted to bind DNA via a helix-turn-helix domain.

80 is predicted to bind DNA, due to its strong helix-turn-helix domain.

81 and a C-terminal circularly permuted winged-helix-turn-helix domain.

82 HP1043 suggested that C215S might affect the helix-turn-helix domain.

83 een the N-terminal domain and the C-terminal helix-turn-helix domain.

84 dimerization domain; a central DNA-binding, helix-turn-helix domain; and an amino-terminal domain re

85 rminal region (NTR), and its C-terminal HTH (helix-turn-helix) domain is also unique in DNA recogniti

86 ore dimerization domain and the DNA-binding, helix-turn-helix, domain.

87 Its helix-turn-helix domains bind A-boxes and the dimer doma

88 ion analysis showed that the RING finger and helix-turn-helix domains of Bmi-1 were required for life

89 eaks these interactions, freeing the LOV and helix-turn-helix domains of each other.

90 otein-DNA bridged complex in which both ParB helix-turn-helix domains simultaneously bind adjacent A-

91 veals interactions between the EL222 LOV and helix-turn-helix domains that we show inhibit DNA bindin

92 a-strand region linking the dimerization and helix-turn-helix domains.

93 tric dimer with extended amino-terminal HTH (helix-turn-helix) domains that contact A-boxes.

94 rough the movement of an arginine-containing helix-turn-helix element at the protein-lipid interface.

95 nge area that links a beta-sheet and a 3(10)-helix-turn-helix element in the N terminus.

96 of the channel-distal from the pore-and the helix-turn-helix extension between segments S2 and S3 pr

97 domain predicted by homology with the winged helix-turn-helix family of activators.

98 ll fold resembles closely that of the winged helix-turn-helix family of DNA-binding proteins.

99 TPR domain proteins, exhibiting the typical helix-turn-helix fold, can be designed by arraying tande

100 lustrating a potentially conserved aspect of helix-turn-helix folding, our results further underscore

101 es, lack canonical signal peptides, and form helix-turn-helix hairpin structures with WXG positioned

102 Pdcd4 MA-3(C) is composed of three layers of helix-turn-helix hairpins capped by a single helix and s

103 onsists of a tetratricopeptide-repeat (TPR), helix-turn-helix (HH), and U-box domain.

104 A conserved helix-turn-helix (HLH) that is part of this site interac

105 These 51 residue proteins, which adopt the helix-turn-helix homeodomain fold, share as few as 12 re

106 osed in unfolding the marginally stable lacI helix-turn-helix (HTH) DNA binding domain using circular

107 model system that links LOV regulation to a helix-turn-helix (HTH) DNA binding domain, we demonstrat

108 R dimer binds to one half of a tra box via a helix-turn-helix (HTH) DNA binding motif.

109 NA, which showed that only one of Rob's dual helix-turn-helix (HTH) DNA binding motifs binds a recogn

110 AraC proteins contain two helix-turn-helix (HTH) DNA binding motifs.

111 The amino-terminal half of EspR is a helix-turn-helix (HTH) DNA-binding domain and the carbox

112 A gene regulatory protein with helix-turn-helix (HTH) DNA-binding motif, GalS contains

113 that are individually recognized by the two helix-turn-helix (HTH) DNA-binding motifs of an ExsA mon

114 nscription regulators whose hallmark is dual helix-turn-helix (HTH) DNA-binding motifs.

115 all-alpha protein that contains a classical helix-turn-helix (HTH) domain and can be assigned to the

116 It is thought to have a helix-turn-helix (HTH) domain at the N-terminus and poss

117 represent a growing subfamily of the winged helix-turn-helix (HTH) domain family whose members share

118 TAN (after PatA N-terminus), and a potential helix-turn-helix (HTH) domain.

119 design and synthesis of peptides with hybrid helix-turn-helix (HTH) motif and their conformational an

120 The helix-turn-helix (HTH) motif features frequently in prot

121 hat the FOXA DNA binding domain folds into a helix-turn-helix (HTH) motif flanked on either side by "

122 to improve the detection of the DNA-binding helix-turn-helix (HTH) motif from sequence.

123 rotein structures containing the DNA-binding helix-turn-helix (HTH) motif has been developed.

124 nally, site-directed mutagenesis of the AmpR helix-turn-helix (HTH) motif identified residues critica

125 When bound to site 1, the first helix-turn-helix (HTH) motif of ExsA interacts with the

126 ng protein with structural similarity to the helix-turn-helix (HTH) motif of the lambda repressor DNA

127 FN-gammaR1 ligand-binding domain and a 57-aa helix-turn-helix (HTH) motif that is structurally relate

128 DNA-binding proteins, CodY appears to have a helix-turn-helix (HTH) motif thought to be critical for

129 tructures occurs in the putative DNA-binding helix-turn-helix (HTH) motif.

130 ree oligonucleotide-binding (OB) folds and a helix-turn-helix (HTH) motif.

131 derivative of Cys420 which is located in the helix-turn-helix (HTH) motif.

132 nsists of an intertwined dimer with a winged helix-turn-helix (HTH) motif.

133 roteins that bind DNA using small contiguous helix-turn-helix (HTH) motifs comprise a significant num

134 MelR binds to 18 bp target sites using two helix-turn-helix (HTH) motifs that are both located in i

135 All members of the AraC family contain two helix-turn-helix (HTH) motifs that contact two segments

136 kingly similar geometries of the EF-hand and helix-turn-helix (HTH) motifs was investigated by NMR an

137 mains, the paired domain (PD), which has two helix-turn-helix (HTH) motifs, and the homeodomain (HD),

138 ator binding, and that the marginally stable helix-turn-helix (HTH) recognition element is greatly st

139 Ala substitutions in two putative helix-turn-helix (HTH) recognition helices that caused d

140 almost exclusively in O157:H7 isolates as a helix-turn-helix (HTH) truncated isoform.

141 We focus on three structural motifs: helix-turn-helix (HTH), helix-hairpin-helix (HhH) and he

142 sis and demonstrate that K52 residues within helix-turn-helix (HTH), K80, R82 and R88 (in the wing) a

143 extensive loop-region (aa 418-530) with two helix-turn-helix (HTH)-like domains, and binds to a heat

144 It is a helix-turn-helix (HTH)-type transcription factor activat

145 a mutation of the loop region of helix-loop-helix-turn-helix in exon 3 of IE1-72 as well as a mutati

146 bulin-like beta-sandwich fold with two extra helix-turn-helix inserts.

147 egion of sigma(70), converting a DNA-binding helix-turn-helix into a continuous pseudohelix.

148 Helix-turn-helix is the simplest alpha-helical structura

149 lavin kinase domain and a DNA-binding winged helix-turn-helix-like domain.

150 kDa T7 protein, Gp5.7, which adopts a winged helix-turn-helix-like structure and specifically repress

151 dated by a flexible linkage between the CcpA helix-turn-helix-loop-helix motif and hinge helices, whi

152 show that RacA contains an N-terminal winged-helix-turn-helix module connected by a disordered region

153 turally related and evolutionarily conserved helix-turn-helix modules within each monomer.

154 -binding site into the engrailed homeodomain helix-turn-helix motif (HTH).

155 ve examined the nature of the highly charged helix-turn-helix motif (S3b and S4) to address how a hig

156 ognition: anti-parallel beta strands (MetR), helix-turn-helix motif + hinge helices (PurR), and zinc

157 putative recognition helix of the predicted helix-turn-helix motif and a basic region near the C ter

158 degrees rigid body rotations of each winged helix-turn-helix motif and DNA dissociation.

159 f the dtxR gene that encodes the DNA-binding helix-turn-helix motif and metal-binding site 1 within d

160 The structure conforms to a helix-bend-helix-turn-helix motif and reveals that the anchor enter

161 ORF157 contains a helix-turn-helix motif and shares no homology with known

162 ra are at residues 78-81, at the turn of the helix-turn-helix motif and the tip of the recognition he

163 ruption of the interface between a conserved helix-turn-helix motif and the top of TMH2.

164 A might use a slightly different part of the helix-turn-helix motif and there appears to be some asso

165 conserved motif that contains a well-folded helix-turn-helix motif and two highly dynamic wings.

166 ed conservation of basic residues within the helix-turn-helix motif and within the beta hairpin loop,

167 recently, we suggested the possibility of a helix-turn-helix motif around a turn encompassing residu

168 e three-helix bundle protein form the native helix-turn-helix motif as an on-pathway intermediate wit

169 FP and the (13)C chemical shifts supported a helix-turn-helix motif at both pH 5.0 and 7.4 with an al

170 bundle containing a pseudo 2-fold axis and a helix-turn-helix motif commonly found in DNA-binding pro

171 NrpR contained a putative N-terminal winged helix-turn-helix motif followed by two mutually homologo

172 SpoIIID was predicted to have a helix-turn-helix motif for sequence-specific DNA binding

173 Two monomers of the helix-turn-helix motif form an antiparallel dimer as ori

174 for the interaction and that Asp(18) of the helix-turn-helix motif forms a component of the interact

175 ratricopeptide repeat (TPR), a 34 amino acid helix-turn-helix motif found in tandem arrays in many na

176 tilt) from central helix C, positioning the helix-turn-helix motif in an unfavorable position for th

177 okaryotic DNA-binding proteins with a single helix-turn-helix motif in its ability to bind DNA monome

178 dues throughout the recognition helix of the helix-turn-helix motif in region 4.2, in contrast to DNA

179 ed a common orientation of the proposed ECL2 helix-turn-helix motif in the binding cavity of cCPE: re

180 g method, we found that ATR interacts with a helix-turn-helix motif in the minimal DNA-binding domain

181 s of mthCdc6-1 mutants demonstrates that the helix-turn-helix motif in the winged-helix domain mediat

182 Here we show that R432 within the helix-turn-helix motif is critical for sequence-specific

183 we obtained direct evidence that the central helix-turn-helix motif of EsxA inserted into the membran

184 tein interaction; the protruding hydrophobic helix-turn-helix motif of one subunit fits into a groove

185 We show that the cytoplasmic helix-turn-helix motif of Thermotoga maritima RodZ direc

186 that the ATR-XPA interaction mediated by the helix-turn-helix motif of XPA plays an important role in

187 hat for DNA binding, ComA uses the conserved helix-turn-helix motif present in other NarL family memb

188 whose amino acid sequence contains a winged helix-turn-helix motif similar to the DNA-binding domain

189 Its predicted helix-turn-helix motif suggested that it has a role as a

190 Each HigA monomer contains a helix-turn-helix motif that binds to its own DNA operato

191 The structure reveals a helix-turn-helix motif that dimerizes to form an antipar

192 ignificant helical secondary structure via a helix-turn-helix motif that inserts the central hydropho

193 Helices 4 and 5 form a classic helix-turn-helix motif that is the putative DNA binding

194 tratricopeptide repeat (TPR) is a 34-residue helix-turn-helix motif that occurs as three or more tand

195 o acid region which potentially folds into a helix-turn-helix motif that specifically binds to the Ca

196 conformational fluctuations that adjust the helix-turn-helix motif to open or close the top of the b

197 main caused by a 6-9 degrees rotation of the helix-turn-helix motif with respect to the rest of the m

198 phaalphabeta subunits are characterized by a helix-turn-helix motif with sequence signature GxxG at t

199 fies an N-terminal cytoplasmic domain with a helix-turn-helix motif, a transmembrane sequence, and a

200 minal DNA-binding domain contains the winged helix-turn-helix motif, and the C-terminal presumed regu

201 that connects the helices of a non-canonical helix-turn-helix motif, and through a concomitant struct

202 e DNA-binding domain of SimR has a classical helix-turn-helix motif, but it also carries an arginine-

203 and characterization generated a 24-residue helix-turn-helix motif, including a 13-residue insertion

204 he complex, the alpha/beta-type SASP adopt a helix-turn-helix motif, interact with DNA through minor

205 In addition to a predicted helix-turn-helix motif, SpoIIID has a C-terminal basic r

206 The helix-turn-helix motif, termed "DELSEED-loop," in the C-

207 The ORF14 protein contains a helix-turn-helix motif, while the ORF16 upstream region

208 he long, flexible loop between them form the helix-turn-helix motif, with the third helix being the r

209 The ARID (A-T Rich Interaction Domain) is a helix-turn-helix motif-based DNA-binding domain, conserv

210 invariant cysteine residues and a conserved helix-turn-helix motif.

211 ing, form the second helix of an unpredicted helix-turn-helix motif.

212 the major groove contact site as a modified helix-turn-helix motif.

213 confirming that DNA binding is mediated by a helix-turn-helix motif.

214 boxyl-terminal domain binds DNA via a winged helix-turn-helix motif.

215 pin domain, a helical hairpin, and bipartite helix-turn-helix motif.

216 s found previously for a naturally occurring helix-turn-helix motif.

217 pecific contacts to the major groove via its helix-turn-helix motif.

218 a three-helix bundle containing a canonical helix-turn-helix motif.

219 d antiparallel beta-barrel and an N-terminal helix-turn-helix motif.

220 the DNA in the classical fashion of a winged helix-turn-helix motif.

221 strongly to DNA through the zinc finger and helix-turn-helix motifs and that DNA binding and catalys

222 irF, it may use both of its carboxy-terminal helix-turn-helix motifs for DNA interaction, and may als

223 w minor grooves using the separation between helix-turn-helix motifs in the Fis dimer as a ruler.

224 in the spatial relationship between the two helix-turn-helix motifs in the Fis dimer upon DNA bindin

225 Since the distance between the two helix-turn-helix motifs is too great to allow binding to

226 The putative helix-turn-helix motifs of Jerky can also bind double-st

227 of alpha-helices in a series of right-handed helix-turn-helix motifs organized into a long rod of len

228 and the unprecedented close spacing between helix-turn-helix motifs present in the apodimer is accom

229 s a unique fold in which three tandem winged helix-turn-helix motifs scaffold a positively charged co

230 anges needed to allow the DNA-binding winged helix-turn-helix motifs to interact with the consecutive

231 y binding to voltage-sensor paddles, crucial helix-turn-helix motifs within the voltage-sensing domai

232 The many alpha-helical HEAT repeats (helix-turn-helix motifs) facilitate bending and allow th

233 As one of the few stable helix-turn-helix motifs, alphatalpha is an excellent mod

234 groove binding wings, an inward movement of helix-turn-helix motifs, and a downward relocation of pl

235 in of AdpA (AdpA-DBD), which consists of two helix-turn-helix motifs, and a target duplex DNA contain

236 extended eukaryotic-like wings, prokaryotic helix-turn-helix motifs, and helix-helix elements.

237 B contains at least three DNA binding winged-helix-turn-helix motifs, and mutations within any of the

238 logs with 98% identity overall and identical helix-turn-helix motifs, for which a previous study neve

239 domain containing two functionally separable helix-turn-helix motifs, resembling the paired domain of

240 N-terminal DNA-binding domain containing two helix-turn-helix motifs.

241 rientation of the two DNA-interacting winged helix-turn-helix motifs.

242 by a complement of DNA contacts made by two helix-turn-helix motifs.

243 tructural features; embedded zinc ribbon and helix-turn-helix motifs.

244 Lrp, including complete conservation of the helix-turn-helix motifs.

245 gions of the two subunits organized with two helix-turn-helix motifs; two globular flaps extending in

246 1.8-A resolution, showing a homodimer with a helix-turn-helix N-terminal domain and a C-terminal doma

247 ecular modeling indicated that a hydrophobic helix-turn-helix near the C terminus of Rdh1 (residues 2

248 urn-helix DNA-binding element similar to the helix-turn-helix of the cI/Cro family of phage repressor

249 n a strikingly similar fashion: a continuous helix-turn-helix of the effectors engages Galphaq within

250 esidues map to the wing domain of the winged helix-turn-helix of ToxR.

251 and alpha-helix 8 of the DNA binding domain (helix-turn-helix) of RegA directly interacted with CbbR,

252 uces alkylhydroperoxide radicals through its helix-turn-helix oxidoreductase motif, the C-terminal do

253 The C-terminal regulatory domain forms a helix-turn-helix plus a long strand.

254 ncluding the typical beta-barrel capped by a helix-turn-helix portal.

255 different locations in the de novo designed helix-turn-helix protein alphatalpha.

256 l and quantitative DNA binding affinities of helix-turn-helix proteins are mapped onto the crystal st

257 omain has a structure that resembles that of helix-turn-helix proteins, LFY and its orthologs represe

258 modes of DNA binding is evident with winged helix-turn-helix proteins, raising doubts that mechanism

259 Residue-level unfolding of two helix-turn-helix proteins--one naturally occurring and o

260 a unique feature of the OmpR group of winged helix-turn-helix proteins.

261 interactions at the protein-DNA interface of helix-turn-helix proteins.

262 ifferent structural classes (zinc-finger and helix-turn-helix), quaternary states (monomeric and dime

263 regions of C are involved in DNA binding: a helix-turn-helix region and a beta-strand region linking

264 , or Arg30 (but not other amino acids in the helix-turn-helix region) to alanine inhibited interactio

265 n-binding domain of scaffolding protein is a helix turn helix structure near the C terminus with a hi

266 o Protein Data Bank (PDB) entry 1CMK , and a helix-turn-helix structure (HTH conformation), similar t

267 rmini disposed toward the cytosol and with a helix-turn-helix structure comprising transmembrane (TM)

268 The helix-turn-helix structure in the C-terminal domain of t

269 phy showed that the large insertion adopts a helix-turn-helix structure positioned as in the Foldit m

270 yeast transcription factor Mbp1 is a winged helix-turn-helix structure, with an extended DNA binding

271 ophobic anchor for maintaining a well-folded helix-turn-helix structure.

272 ltage-sensor paddles'-hydrophobic, cationic, helix-turn-helix structures on the channel's outer perim

273 The thermal unfolding of a 40-residue helix-turn-helix subdomain of the P22 viral coat protein

274 The structure reveals a novel helix-turn-helix subdomain that is allosterically couple

275 PhoPC exhibits a typical fold of the winged helix-turn-helix subfamily of response regulators.

276 The stem region is a unique three-stranded helix-turn-helix supercoil that has not previously been

277 f an N-terminal DNA binding domain of winged helix-turn-helix topology and a C-terminal dimerization

278 (TPR) domains consist of three copies of the helix-turn-helix TPR motif, together with a seventh C-te

279 odomain protein CEH-14 through CEH-63 to the helix-turn-helix transcription factor MBR-1.

280 We report that SciP, a helix-turn-helix transcription factor, is an essential c

281 f this simplification, we compared two small helix-turn-helix transcription factors with different en

282 NanR, one of >8,500 GntR superfamily helix-turn-helix transcriptional regulators, controls ex

283 rate reduction regulatory protein) family of helix-turn-helix transcriptional regulators.

284 acid synthase (fab) genes is controlled by a helix-turn-helix transcriptional repressor called FabT.

285 that the RING finger, as well as a conserved helix-turn-helix-turn domain, were required for its abil

286 BMI1 consists of a ring finger (RF), helix-turn-helix-turn-helix-turn (HT), proline/serine (P

287 Homeodomains are helix-turn-helix type DNA-binding domains that exhibit s

288 ator, IscR, is a transcription factor of the helix-turn-helix type that can coordinate a [2Fe-2S] clu

289 NilR contains a helix-turn-helix-type DNA binding domain and likely acts

290 1C) was found to comprise two related winged helix-turn-helix (WH) motifs, one of which is most simil

291 Additional result showed that a helix-turn-helix WHEP domain that was appended to GlyRS

292 MxiH (8.3 kDa) is a helix-turn-helix, whereas IpaD (36.6 kDa) has a dumbbell

293 r complexes and contain an N terminal winged helix-turn-helix (wHTH) DNA binding domain (DBD).

294 dimer, with each monomer harboring a winged helix-turn-helix (WHTH) DNA-binding motif.

295 , FhlA) domain that binds BCAAs and a winged helix-turn-helix (wHTH) domain that binds to DNA, but th

296 olase-like domain and the DNA-binding winged-helix-turn-helix (wHTH) domain.

297 se of Escherichia coli belongs to the winged helix-turn-helix (wHTH) family of transcriptional regula

298 TFs with winged helix-turn-helix (wHTH) motifs use an alpha helix to rea

299 PF0610 is a novel winged helix-turn-helix (wHTH) protein with a rubredoxin-like Z

300 toplasmic domain is homologous to the winged helix-turn-helix ('winged helix') DNA-binding/transcript