ライフサイエンスコーパス: help elucidate

1 These findings may help elucidate a deeper mechanistic understanding of the

2 key F. tularensis effector protein, and may help elucidate a mechanistic understanding of F. tularen

3 ething rarely done in a range-limit context, helps elucidate a mechanistic understanding of range con

4 within cellular and animal models as well as help elucidate aberrant proteolytic function correlated

5 ht interfere with essential MA functions and help elucidate additional features of MA binding.

6 enase-2 inhibitors with regional blocks, may help elucidate and clarify the true benefits of perioper

7 re no published Guanche autosomal genomes to help elucidate and directly test this hypothesis.

8 A relatively unbiased method, as such, will help elucidate any potential associations between advers

9 selective, sensitive, and rapid method will help elucidate any potential associations between human

10 human chronic myeloid leukemia (CML) and may help elucidate basic leukemogenic mechanisms in CML stem

11 mechanisms underlying these associations may help elucidate biological mechanisms influencing sleep d

12 eterogeneity of colorectal neoplasia and may help elucidate carcinogenic mechanisms for distinct path

13 o-profiling of rare cell populations and may help elucidate correlates of protection for a variety of

14 occur during senescence/immortalization may help elucidate crucial events that lead to cell transfor

15 An Fe(2+)/Fe(3+) redox couple was used to help elucidate details of the band diagram.

16 emonstrates how a computational approach can help elucidate developing ELNs and their impact on tumor

17 These results help elucidate differences between the initial negative

18 nical and biomarker fingerprint profiles may help elucidate disease subtypes as well as response to t

19 l inconsistencies between similar components help elucidate DOM properties for which fluorescence spe

20 reinforcement learning techniques that have helped elucidate dopamine's role in appetitive behavior.

21 ical and genomic profiling technologies have helped elucidate early and late diversification mechanis

22 arking risk for psychotic illness and it may help elucidate etiological underpinnings of psychotic di

23 To help elucidate expansin's mechanism of wall loosening, w

24 method will find a significant hit that can help elucidate function.

25 equencing of protein-coding genes, which can help elucidate functional differences among microbial co

26 ng with the recent advances in genetics, has helped elucidate further roles of primary cilia beyond s

27 patiotemporal context of expression data and help elucidate gene function.

28 Their combined use can help elucidate gene regulation 'logic' by aiding in targ

29 CML and its progression to blast crisis may help elucidate general mechanisms of carcinogenesis and

30 ogonal RNA transcription regulators, and may help elucidate general principles of non-coding RNA regu

31 ioral measures linked to brain circuitry can help elucidate genetic mechanisms contributing to defici

32 for regulatory factor interactions that will help elucidate genome function and the implementation of

33 vide new drug and vaccine targets and should help elucidate hookworm pathogenesis.

34 body assembly and maturation to date and may help elucidate how abscission sites are positioned and r

35 These results help elucidate how cortical processing exploits spatial

36 These findings can help elucidate how faster processes can organize, transp

37 To help elucidate how general the role of dopamine (DA) rel

38 The characterization of mutant lines can help elucidate how recombination is controlled.

39 dy mass and its demographic consequences can help elucidate how social and environmental factors affe

40 nmental field work, laboratory evolution may help elucidate how these bacteria have so successfully a

41 ion antimalarial drug-heme structures should help elucidate how these drugs inhibit formation of hemo

42 es that regulate EGFR signaling in vivo will help elucidate how this pathway can become inappropriate

43 e to EBV and disease risk across cancers may help elucidate how this ubiquitous virus contributes to

44 These reports help elucidate how transcriptional regulators are themse

45 ng of the translation initiation process and helped elucidate how modifications of the general transl

46 Model systems have helped elucidate how secretion systems function at both

47 broader view of neural circuit dynamics and helping elucidate how brain regions work in concert to s

48 Genomic biology offers promise in helping elucidate in greater detail how nutrient utiliza

49 ll the proposed computational frameworks can help elucidate input/output relationships of signaling n

50 biologically active peptides into cells may help elucidate intracellular signal transduction pathway

51 To help elucidate its early responses to a decrease in nitr

52 In order to help elucidate its function, we undertook a determinatio

53 tion and fibrillation pathway of hSAA1.1 may help elucidate its pathological role.

54 tion of C9orf72 protein isoforms, which will help elucidate its physiological function and role in AL

55 AcroB may help elucidate key aspects of mitochondria electrophile

56 These results should help elucidate Li(+) intercalation motifs between curved

57 a can, with great spatiotemporal resolution, help elucidate local disease patterns.

58 These results may help elucidate lower than expected mortality rates obser

59 ts luminally exposed to high CO(2) saline to help elucidate luminal acid-sensing mechanisms.

60 interest since its discovery in 1980 and has helped elucidate many important aspects of quantum physi

61 Recent discoveries have helped elucidate many of the processes involved in cell

62 enetic disease screening/diagnosis and might help elucidate mechanisms and pathways that lead to geno

63 Further genomic and functional analyses may help elucidate mechanisms by which tumor cells metastasi

64 ed spermatogonia, including SSCs, which will help elucidate mechanisms controlling the earliest cell

65 These investigations were conducted to help elucidate mechanisms for improving olefin hydrogena

66 notypes associated with expression and could help elucidate mechanisms of intestinal disease.

67 C2-8 provides an essential tool to help elucidate mechanisms of neurodegeneration in HD and

68 preventive HIV-1 vaccine efficacy trial can help elucidate mechanisms of partial protection.

69 Understanding this difference may help elucidate mechanisms of pathogenesis.

70 udy of the loci identified in this study may help elucidate mechanisms of phosphorus regulation.

71 s to paired computational studies that often help elucidate mechanisms of the observed behavior.

72 e models with direct CD4 alloreactivity will help elucidate mechanisms of transplant rejection and to

73 They help elucidate mechanisms underlying campomelic dysplasi

74 In addition, this methodology may help elucidate mechanistic pathways linking diet to chro

75 ood agreement with available experiments and help elucidate melanin's role in photoprotection against

76 contributions, these markers show promise to help elucidate mnemonic processing in TLE.

77 xpression profiling and ER protein assays to help elucidate molecular mechanism(s) responsible for ta

78 ors often use these datasets individually to help elucidate molecular mechanisms of human diseases.

79 Mouse models have helped elucidate MYCN functions; however its cardiac-spe

80 Our results help elucidate nanomedicines' in vivo fate and provide g

81 These findings help elucidate neural mechanisms of anhedonia, as a step

82 These findings help elucidate neurochemical substrates of choice, with

83 fication of numerous mutants whose study has helped elucidate new mechanisms in cardiac development.

84 sq1) mice might represent a valuable tool to help elucidate novel aspects of TLR7 biology.

85 suprachiasmatic nucleus, these findings will help elucidate novel mechanisms modulating circadian flu

86 ncer profiles, we showed that using pi-value helps elucidating otherwise overlooked important biologi

87 hanges seen in malnourished children and may help elucidate our understanding of long-term metabolic

88 pha-synuclein, parkin, and other genes, have helped elucidate pathogenesis.

89 These findings help elucidate possible mechanisms of nitrite-induced ca

90 angiotensinogen (AGT) as a candidate gene to help elucidate potential mechanisms for previously repor

91 results also show how a systems approach can help elucidate potential mechanisms of action and advers

92 at nanoscale remains a challenge that could help elucidate processes in biology, medicine and techno

93 Indeed, models can help elucidate properties of these networks, understand

94 y computational tools have been developed to help elucidate protein function.

95 sA from Streptomyces lividans can be used to help elucidate questions about channel inactivation and

96 traits influenced by a common group of genes helps elucidate regulatory networks and can improve link

97 Our proposed method may help elucidate relationships among key mutations and the

98 Eye tracking has helped elucidate relationships between eye movements, vi

99 binding sites around alternative exons will help elucidate splicing regulation by RBPs.

100 in vitro hydrogenase activation methods have helped elucidate steps in the H-cluster biosynthetic pat

101 These results may help elucidate the ability of mu agonists to regulate th

102 otspots at mutant amino acid resolution will help elucidate the allele-specific differences in their

103 These findings help elucidate the amino acid side chains involved in DN

104 model of the ICE electric field was used to help elucidate the antifouling mechanism in solution.

105 These findings may help elucidate the apparently contradicting results of c

106 To help elucidate the assembly mechanism of the nucleocapsi

107 ell as the analytical method, can be used to help elucidate the axonal transport impairments observed

108 human non-small cell lung cancer (NSCLC) may help elucidate the basis for its dismal prognosis.

109 umbers, a larger multi-institution study may help elucidate the benefits of T2 mapping as an adjuncti

110 Specific inhibitors may also help elucidate the biochemical roles of each Hsp90 paral

111 stratification may reduce heterogeneity and help elucidate the biological basis of complex neuropsyc

112 the potential for this monogenic disorder to help elucidate the biological features of idiopathic aut

113 To help elucidate the biological function of PRMT6 in vivo,

114 ification of cellular PTPase substrates will help elucidate the biological functions of individual PT

115 To help elucidate the biological functions of M6P/IGF2R in

116 isease status but also cognitive function to help elucidate the biological pathway from gene to brain

117 These findings may help elucidate the biological validity of similar findin

118 ating activity of the amygdala in humans and help elucidate the causal neural interactions that under

119 Further study of SSPCs may help elucidate the cellular and molecular mechanism of s

120 Ice-COLD-PCR will help elucidate the clinical significance of low-abundanc

121 In sum, our comprehensive data help elucidate the complex binding landscape of C2H2-ZF

122 These findings help elucidate the complex communication that occurs in

123 These findings help elucidate the complex nature of CD28 gene regulatio

124 ng regulation of PI 3-kinase activity should help elucidate the complexity of the IR signaling mechan

125 These findings may help elucidate the connection between key local events a

126 he findings constitute new evidence that may help elucidate the consequences of H.M.'s operation in t

127 f selection to aging within a population and help elucidate the contribution of aging itself to the v

128 llular trafficking of PrP(C) may, therefore, help elucidate the conversion process.

129 ween consolation and empathy, these findings help elucidate the development of individual socio-cogni

130 These mechanisms may help elucidate the differential mutational statistics in

131 three complementary animal models that will help elucidate the disease mechanism.

132 presented along with computational data that help elucidate the efficacy that 1 imparts on Suzuki-Miy

133 factors that underlie these differences may help elucidate the etiology and prevention of hip OA.

134 neation of such defining characteristics may help elucidate the etiology and prognosis of such tumors

135 iological arousal and later child PTSD could help elucidate the etiology of posttrauma responses in c

136 n be relatively safe in this population, may help elucidate the etiology of renal failure, may predic

137 sed attention to events in this interval may help elucidate the etiology of TGCTs.

138 c regulation of melanoblast development will help elucidate the etiology of these and other neurocris

139 ng commonalities between lncRNA systems will help elucidate the evolution and mechanistic role of lnc

140 uture studies of the first years of life may help elucidate the factors and processes that bring abou

141 Our findings help elucidate the factors structuring marine mammal mic

142 Calculations help elucidate the factors that underlie the selective b

143 tly enhanced reproducibility are expected to help elucidate the formation mechanism of this interesti

144 oteins and their structural interactions may help elucidate the formation of the polar tube during th

145 iptional meta-analysis was also conducted to help elucidate the function of the CLE peptide family me

146 Studies of THRUMIN1 will help elucidate the function of this family of eukaryotic

147 These findings help elucidate the functional differences that result fr

148 To help elucidate the functions of the large number of PFam

149 um of laboratories utilizing metabolomics to help elucidate the functions of uncharacterized genes.

150 d pathways, and cellular phenotypes that may help elucidate the genetic basis of childhood HSE.

151 landraces from a broad geographical range to help elucidate the genetic basis of local adaptation.

152 This work should help elucidate the hydrolytic ring-opening mechanism of

153 ron and high resolution x-ray diffraction to help elucidate the identity of the catalytic base in the

154 The two boundaries help elucidate the in vivo binding structure of a given

155 that genetics and developmental biology can help elucidate the in vivo site of action of pharmacolog

156 lity of intermolecular interactions may also help elucidate the interactions of the molecular nanofib

157 These findings help elucidate the link between compulsive eating and an

158 els that develop dysplasia and neoplasia may help elucidate the link between inflammation and colorec

159 Our results also help elucidate the link between RBC dyscrasias and cardi

160 y of selective pressures on individuals will help elucidate the maintenance of microbial diversity an

161 Results of this comparison will help elucidate the manner in which discreet DNA modules

162 ns ubiquitous in key cellular processes, and help elucidate the mechanism and pathological significan

163 ng a catalytic intermediate that promises to help elucidate the mechanism of catalysis.

164 ribution and evolution of these sites and to help elucidate the mechanism of frameshifting, we determ

165 KvDMR1 into its functional components should help elucidate the mechanism of its function in vivo.

166 he protein SP-B, whose structure promises to help elucidate the mechanism of its function.

167 pendent biological activities of PDNF should help elucidate the mechanism of PDNF activation of TrkA-

168 Our study provides new data that will help elucidate the mechanism of PM10-mediated lung cance

169 To help elucidate the mechanism of prevention of colonizati

170 To help elucidate the mechanism of protein inactivation med

171 ponse induced by the vaccine have promise to help elucidate the mechanism of SAEs.

172 define the role of OTT1 in hematopoiesis and help elucidate the mechanism of t(1,22) acute megakaryoc

173 ork was to obtain new information that might help elucidate the mechanism of T2 distribution in muscl

174 These findings may help elucidate the mechanism underlying arterivirus repl

175 ion, and mechanical systolic performance may help elucidate the mechanism underlying the observed glo

176 hin the Aec1 and Aec2 genetic regions should help elucidate the mechanism(s) underlying SS-like disea

177 imental characterization and in so doing may help elucidate the mechanisms and biological implication

178 ion of these findings in further studies may help elucidate the mechanisms behind this short-term inc

179 To help elucidate the mechanisms behind XMRV infection, we

180 APOL1 may provide clues that will ultimately help elucidate the mechanisms by which APOL1 variants pr

181 These findings may help elucidate the mechanisms by which chronic asymptoma

182 expression in response to E2F-1 in order to help elucidate the mechanisms by which E2F-1 causes apop

183 ow mutant TBP mediates neuropathology should help elucidate the mechanisms by which transcriptional d

184 ecular fingerprint (gene profile) of IC will help elucidate the mechanisms involved and suggest furth

185 To help elucidate the mechanisms involved in the block in p

186 the Wolff-Parkinson-White (WPW) syndrome to help elucidate the mechanisms of accessory pathway forma

187 pattern of T cell differentiation that might help elucidate the mechanisms of HCV immunity and pathog

188 ering protective genetic variants that could help elucidate the mechanisms of Mendelian diseases and

189 SA signaling network in plants, and may also help elucidate the mechanisms through which SA acts as a

190 We anticipate that these findings will help elucidate the mechanisms underlying HCM development

191 epts and simplifying modeling approaches may help elucidate the mechanisms underlying other cellular

192 To help elucidate the mechanisms underlying this phenomenon

193 fold and unfold, have recently been used to help elucidate the mechanistic principles that underlie

194 residues at the inhibitor-binding site will help elucidate the molecular basis for fusion activation

195 crystal structures and enzymological studies help elucidate the molecular basis of LovC specificity,

196 aspartate-prone proteins identified here may help elucidate the molecular basis of one or more develo

197 transcriptional regulatory sites in vivo to help elucidate the molecular basis of sex-related differ

198 Expression profiling of pure DCIS will help elucidate the molecular characteristics that distin

199 al outcome of a mutation, and can be used to help elucidate the molecular mechanism of disease/cancer

200 Our findings help elucidate the molecular mechanisms by which transcr

201 These models also help elucidate the molecular mechanisms of corneal epith

202 Identification of the causal alleles will help elucidate the molecular mechanisms responsible for

203 ypoparathyroidism-associated GCMB mutations, help elucidate the molecular mechanisms underlying DNA-b

204 characterization of these stem cells should help elucidate the molecular pathways that govern normal

205 ochemical dissection of this reaction should help elucidate the molecular requirements and hierarchy

206 tionary success of the ssDNA viruses and may help elucidate the mystery of integrated RNA viruses in

207 and functional ortholog of mammalian MCH and help elucidate the nature of MCH evolution among vertebr

208 lysis of intrinsic connectivity networks may help elucidate the neural architectures that support fun

209 These findings help elucidate the neural systems-level effects of methy

210 s of OT and OTR in social recognition should help elucidate the neurobiological bases of human disord

211 k towards postmortem human brain research to help elucidate the neurobiological underpinnings of MRI

212 ght-induced melatonin suppression that could help elucidate the ocular photoreceptor system for regul

213 To help elucidate the origins of the RAG genes, we have clo

214 These results not only help elucidate the origins of the TM(n+):TiO(2) DMS ferr

215 Our findings help elucidate the paracrine signaling events activated

216 y symptoms after HSC transplantation and may help elucidate the pathogenesis of idiopathic BOOP.

217 These observations could help elucidate the pathogenesis of the disease.

218 rther characterization of Vitamin D/VDR will help elucidate the pathogenesis of various human disease

219 The double-mutant mice will help elucidate the pathophysiological mechanisms underly

220 novel mouse model of BONJ-like disease will help elucidate the pathophysiology of BONJ and ultimatel

221 choroidal vasculature at variable depths may help elucidate the pathophysiology of disease and can co

222 More data are needed to help elucidate the pathophysiology of this syndrome.

223 chronic inflammatory disease models that can help elucidate the pathophysiology of vascular inflammat

224 sensitive detection of CCC DNA, which should help elucidate the pathways of CCC DNA formation and the

225 and temporal resolution in intact organs may help elucidate the players involved.

226 ion in this model of open-angle glaucoma may help elucidate the primary changes occurring at the mole

227 ormational effects, the study of which might help elucidate the proton-coupled electron-transfer mech

228 s pave the way for further investigations to help elucidate the relationships between telomere length

229 s of neonatal Kiss1 and ERs mRNA levels will help elucidate the relative roles each plays in the sex-

230 These findings help elucidate the relative roles of visual experience v

231 he H5N1 isolates from different countries to help elucidate the risk of a human pandemic from the str

232 ease and suggest research avenues that might help elucidate the role of activated platelets in CF.

233 Controlled clinical trials now underway will help elucidate the role of AVP receptor antagonism in th

234 To help elucidate the role of CSP41 in chloroplast gene reg

235 -8 receptors have been identified, which may help elucidate the role of interleukin-8 and related che

236 echanisms of microRNA transcription, and can help elucidate the role of microRNA as mediators of comp

237 e and host-microbe chemical cross-talk would help elucidate the role of our gut microbiota in health

238 tinum-DNA damage by DNA repair processes and help elucidate the role of specific post-translational m

239 he Cu-induced transcriptome generated should help elucidate the role of the Cu response in maintainin

240 ties influence the metabolic environment may help elucidate the role of the microbiota in disease dev

241 tions into the regulation of this system may help elucidate the role of the Ysps during the life cycl

242 eloped based on binding domain structures to help elucidate the role of this enzyme in the central ne

243 This strategy is poised to help elucidate the role of variants at the low end of th

244 is mouse model provides a powerful system to help elucidate the specific metabolic mechanisms that un

245 cyclin degradation that we report here could help elucidate the specific roles of the redundant CDK-c

246 The results help elucidate the structural origins of the extreme ant

247 A54 and T54 I-FABP has now been performed to help elucidate the structural origins of their physiolog

248 campus, and provides a promising approach to help elucidate the synaptic basis of long-term memory.

249 temporally distinct, and this difference may help elucidate the therapeutic window for use of antivir

250 le probes to the DAT protein will ultimately help elucidate the three-dimensional arrangement of the

251 EYA-SO targets identified in this study will help elucidate the transcriptional circuitries whereby o

252 or a broad array of imaging applications and help elucidate the underlying biologic processes relevan

253 known functional information into GWASs can help elucidate the underlying biological mechanisms and

254 eeded in these secondary forms of disease to help elucidate the underlying cause and pathogenesis of

255 nd understanding their normal functions will help elucidate the underlying causes of these disorders.

256 The ability to discern such patterns can help elucidate the underlying mechanisms and guide antia

257 discoveries with psychological processes and help elucidate the underlying neural mechanisms.

258 We propose a mathematical model that may help elucidate the underlying physiological mechanism re

259 mplications for arbovirus evolution and will help elucidate the viral factors responsible for the bro

260 Recent studies helped elucidate the cellular and molecular basis of PDC

261 ng individuals in households or schools have helped elucidate the determinants of transmission in sma

262 nsfer in donor-bridge-acceptor molecules has helped elucidate the distance dependence of electron tra

263 erate to large contemporary case series have helped elucidate the early natural history, presenting c

264 abricated and nanofabricated structures have helped elucidate the effects of nanoscale spatial confin

265 ithin- versus between-individual variability helped elucidate the factors contributing to the conside

266 nt studies using Cre-LoxP recombination have helped elucidate the function of LRP1 in mature normal a

267 Insights from basic science research have helped elucidate the mechanisms by which metabolism-base

268 This has helped elucidate the mechanisms of several mutations and

269 Two, a large body of work has helped elucidate the molecular details underlying the Ne

270 Recent literature is summarized that has helped elucidate the pathophysiologic basis for their oc

271 tion of the HJ in three different directions helped elucidate the structures of the transient species

272 In addition to helping elucidate the role of B cells in MS, our approac

273 Our work helps elucidate the ambiguity concerning the role of TGF

274 onale for selectivity at the molecular level helps elucidate the biological function and design of sp

275 Mathematical modeling helps elucidate the biological mechanisms at play as the

276 resolution of the conformational transitions helps elucidate the complex chaperone machinery.

277 This work helps elucidate the design rules by which simple logic c

278 ed explanatory variables is developed, which helps elucidate the factors contributing to elevated (22

279 Using our method, we provide a resource that helps elucidate the functional and spatial organization

280 ain coarsening in the plasticized film which helps elucidate the mechanism by which additives improve

281 tractile property of cardiomyocytes not only helps elucidate the pathophysiology of heart failure but

282 This finding helps elucidate the relative role of surface exposure of

283 tic step performed by key conserved residues-helps elucidate the structure-function relationships of

284 rity analysis of biological time series data helps elucidate the varying dynamics of biological syste

285 al, religious, and medical significance, and help elucidate their earliest descriptions in the Shang

286 hem into chemically meaningful fragments can help elucidate their functional properties, and may be u

287 Genetic association studies may help elucidate their origin and function.

288 ties of pesticide exposure, they nonetheless help elucidate their risks to colony health.

289 To help elucidate these roles, we have characterized the fi

290 ng UL97 function and maribavir action should help elucidate this interesting biological process and h

291 To help elucidate this process, we examined the binding act

292 To help elucidate this, we generated a mouse strain carryin

293 ng a set of microarray samples as input, can help elucidate tightly coexpressed gene sets (modules) t

294 cation of changes most specific to HFpEF may help elucidate underlying pathophysiology.

295 annotation of the mammalian genome that will help elucidate various human disease genes and pathways.

296 tional redundancy for Drpr in Drosophila may help elucidate whether paralogs of MEGF10 in humans (eg,

297 This new understanding helps elucidate which microstructural features need to b

298 contacts than from drinking water, which may help elucidate why interventions focused on water withou

299 ell compartments uniquely place zebrafish to help elucidate why mammals possess such low capacity to

300 Thus, these simulations also help elucidate why some inhibitory serpin families are m