ライフサイエンスコーパス: help( to|) elucidate

1 These findings may help elucidate a deeper mechanistic understanding of the

2 key F. tularensis effector protein, and may help elucidate a mechanistic understanding of F. tularen

3 within cellular and animal models as well as help elucidate aberrant proteolytic function correlated

4 ht interfere with essential MA functions and help elucidate additional features of MA binding.

5 derstanding how BLM and FANCJ cooperate will help to elucidate an important pathway for maintaining g

6 enase-2 inhibitors with regional blocks, may help elucidate and clarify the true benefits of perioper

7 re no published Guanche autosomal genomes to help elucidate and directly test this hypothesis.

8 The methodology presented here would help to elucidate and predict novel networks and potenti

9 A relatively unbiased method, as such, will help elucidate any potential associations between advers

10 selective, sensitive, and rapid method will help elucidate any potential associations between human

11 retinal regeneration in these organisms will help to elucidate approaches to stimulate a similar resp

12 mechanisms underlying these associations may help elucidate biological mechanisms influencing sleep d

13 eterogeneity of colorectal neoplasia and may help elucidate carcinogenic mechanisms for distinct path

14 o-profiling of rare cell populations and may help elucidate correlates of protection for a variety of

15 nctional studies of these novel genes should help to elucidate critical early steps leading to the fo

16 occur during senescence/immortalization may help elucidate crucial events that lead to cell transfor

17 An Fe(2+)/Fe(3+) redox couple was used to help elucidate details of the band diagram.

18 emonstrates how a computational approach can help elucidate developing ELNs and their impact on tumor

19 These results help elucidate differences between the initial negative

20 nical and biomarker fingerprint profiles may help elucidate disease subtypes as well as response to t

21 Vs) may represent novel effectors that might help to elucidate disease-specific pathways in metabolic

22 l inconsistencies between similar components help elucidate DOM properties for which fluorescence spe

23 arking risk for psychotic illness and it may help elucidate etiological underpinnings of psychotic di

24 To help elucidate expansin's mechanism of wall loosening, w

25 ntial energy surface, are in accord with and help to elucidate experiment.

26 method will find a significant hit that can help elucidate function.

27 equencing of protein-coding genes, which can help elucidate functional differences among microbial co

28 patiotemporal context of expression data and help elucidate gene function.

29 Their combined use can help elucidate gene regulation 'logic' by aiding in targ

30 CML and its progression to blast crisis may help elucidate general mechanisms of carcinogenesis and

31 ogonal RNA transcription regulators, and may help elucidate general principles of non-coding RNA regu

32 ioral measures linked to brain circuitry can help elucidate genetic mechanisms contributing to defici

33 for regulatory factor interactions that will help elucidate genome function and the implementation of

34 vide new drug and vaccine targets and should help elucidate hookworm pathogenesis.

35 nd pathogenicity, their further study should help to elucidate host-virus interactions that determine

36 body assembly and maturation to date and may help elucidate how abscission sites are positioned and r

37 These results help elucidate how cortical processing exploits spatial

38 These findings can help elucidate how faster processes can organize, transp

39 To help elucidate how general the role of dopamine (DA) rel

40 The characterization of mutant lines can help elucidate how recombination is controlled.

41 dy mass and its demographic consequences can help elucidate how social and environmental factors affe

42 nmental field work, laboratory evolution may help elucidate how these bacteria have so successfully a

43 es that regulate EGFR signaling in vivo will help elucidate how this pathway can become inappropriate

44 e to EBV and disease risk across cancers may help elucidate how this ubiquitous virus contributes to

45 virions to transduce nondividing cells could help to elucidate incompletely understood mechanisms of

46 ll the proposed computational frameworks can help elucidate input/output relationships of signaling n

47 In order to help elucidate its function, we undertook a determinatio

48 tion and fibrillation pathway of hSAA1.1 may help elucidate its pathological role.

49 tion of C9orf72 protein isoforms, which will help elucidate its physiological function and role in AL

50 bility of FAN1 to traverse ICLs in DNA could help to elucidate its biological function, which is curr

51 protein subcellular localization can greatly help to elucidate its functions.

52 AcroB may help elucidate key aspects of mitochondria electrophile

53 These results should help elucidate Li(+) intercalation motifs between curved

54 a can, with great spatiotemporal resolution, help elucidate local disease patterns.

55 These results may help elucidate lower than expected mortality rates obser

56 ts luminally exposed to high CO(2) saline to help elucidate luminal acid-sensing mechanisms.

57 Further genomic and functional analyses may help elucidate mechanisms by which tumor cells metastasi

58 ed spermatogonia, including SSCs, which will help elucidate mechanisms controlling the earliest cell

59 These investigations were conducted to help elucidate mechanisms for improving olefin hydrogena

60 notypes associated with expression and could help elucidate mechanisms of intestinal disease.

61 C2-8 provides an essential tool to help elucidate mechanisms of neurodegeneration in HD and

62 preventive HIV-1 vaccine efficacy trial can help elucidate mechanisms of partial protection.

63 Understanding this difference may help elucidate mechanisms of pathogenesis.

64 udy of the loci identified in this study may help elucidate mechanisms of phosphorus regulation.

65 s to paired computational studies that often help elucidate mechanisms of the observed behavior.

66 e models with direct CD4 alloreactivity will help elucidate mechanisms of transplant rejection and to

67 They help elucidate mechanisms underlying campomelic dysplasi

68 earing animal models, and bacterial genetics help to elucidate mechanisms by which P aeruginosa survi

69 The observations may help to elucidate mechanisms involved in the molecular p

70 These findings help to elucidate mechanisms of HIV-1 disease progressio

71 lues) and functional genomic datasets should help to elucidate mechanisms.

72 In addition, this methodology may help elucidate mechanistic pathways linking diet to chro

73 ood agreement with available experiments and help elucidate melanin's role in photoprotection against

74 contributions, these markers show promise to help elucidate mnemonic processing in TLE.

75 xpression profiling and ER protein assays to help elucidate molecular mechanism(s) responsible for ta

76 ors often use these datasets individually to help elucidate molecular mechanisms of human diseases.

77 Further testing may help to elucidate more accurate trends, as well as nonli

78 ges that occur in obese individuals may also help to elucidate more effective treatment options for t

79 Our results help elucidate nanomedicines' in vivo fate and provide g

80 These findings help elucidate neural mechanisms of anhedonia, as a step

81 These findings help elucidate neurochemical substrates of choice, with

82 which genes and their products interact can help to elucidate normal cell physiology as well as the

83 sq1) mice might represent a valuable tool to help elucidate novel aspects of TLR7 biology.

84 suprachiasmatic nucleus, these findings will help elucidate novel mechanisms modulating circadian flu

85 hanges seen in malnourished children and may help elucidate our understanding of long-term metabolic

86 light on analogous functions in mammals and help to elucidate pathomechanisms of neurological abnorm

87 These findings help elucidate possible mechanisms of nitrite-induced ca

88 results also show how a systems approach can help elucidate potential mechanisms of action and advers

89 These findings help to elucidate potential neural mechanisms of emotion

90 PET might thus help to elucidate potential therapeutic targets and be u

91 at nanoscale remains a challenge that could help elucidate processes in biology, medicine and techno

92 Indeed, models can help elucidate properties of these networks, understand

93 y computational tools have been developed to help elucidate protein function.

94 sA from Streptomyces lividans can be used to help elucidate questions about channel inactivation and

95 pic mechanisms which, with future study, may help to elucidate radiobiological responses along the Br

96 Our proposed method may help elucidate relationships among key mutations and the

97 binding sites around alternative exons will help elucidate splicing regulation by RBPs.

98 otspots at mutant amino acid resolution will help elucidate the allele-specific differences in their

99 These findings help elucidate the amino acid side chains involved in DN

100 model of the ICE electric field was used to help elucidate the antifouling mechanism in solution.

101 These findings may help elucidate the apparently contradicting results of c

102 To help elucidate the assembly mechanism of the nucleocapsi

103 ell as the analytical method, can be used to help elucidate the axonal transport impairments observed

104 human non-small cell lung cancer (NSCLC) may help elucidate the basis for its dismal prognosis.

105 umbers, a larger multi-institution study may help elucidate the benefits of T2 mapping as an adjuncti

106 Specific inhibitors may also help elucidate the biochemical roles of each Hsp90 paral

107 stratification may reduce heterogeneity and help elucidate the biological basis of complex neuropsyc

108 the potential for this monogenic disorder to help elucidate the biological features of idiopathic aut

109 To help elucidate the biological function of PRMT6 in vivo,

110 isease status but also cognitive function to help elucidate the biological pathway from gene to brain

111 These findings may help elucidate the biological validity of similar findin

112 ating activity of the amygdala in humans and help elucidate the causal neural interactions that under

113 Further study of SSPCs may help elucidate the cellular and molecular mechanism of s

114 Ice-COLD-PCR will help elucidate the clinical significance of low-abundanc

115 In sum, our comprehensive data help elucidate the complex binding landscape of C2H2-ZF

116 These findings help elucidate the complex communication that occurs in

117 These findings help elucidate the complex nature of CD28 gene regulatio

118 These findings may help elucidate the connection between key local events a

119 he findings constitute new evidence that may help elucidate the consequences of H.M.'s operation in t

120 f selection to aging within a population and help elucidate the contribution of aging itself to the v

121 llular trafficking of PrP(C) may, therefore, help elucidate the conversion process.

122 ween consolation and empathy, these findings help elucidate the development of individual socio-cogni

123 These mechanisms may help elucidate the differential mutational statistics in

124 three complementary animal models that will help elucidate the disease mechanism.

125 presented along with computational data that help elucidate the efficacy that 1 imparts on Suzuki-Miy

126 neation of such defining characteristics may help elucidate the etiology and prognosis of such tumors

127 iological arousal and later child PTSD could help elucidate the etiology of posttrauma responses in c

128 n be relatively safe in this population, may help elucidate the etiology of renal failure, may predic

129 sed attention to events in this interval may help elucidate the etiology of TGCTs.

130 c regulation of melanoblast development will help elucidate the etiology of these and other neurocris

131 ng commonalities between lncRNA systems will help elucidate the evolution and mechanistic role of lnc

132 Our findings help elucidate the factors structuring marine mammal mic

133 Calculations help elucidate the factors that underlie the selective b

134 tly enhanced reproducibility are expected to help elucidate the formation mechanism of this interesti

135 oteins and their structural interactions may help elucidate the formation of the polar tube during th

136 iptional meta-analysis was also conducted to help elucidate the function of the CLE peptide family me

137 Studies of THRUMIN1 will help elucidate the function of this family of eukaryotic

138 These findings help elucidate the functional differences that result fr

139 To help elucidate the functions of the large number of PFam

140 um of laboratories utilizing metabolomics to help elucidate the functions of uncharacterized genes.

141 d pathways, and cellular phenotypes that may help elucidate the genetic basis of childhood HSE.

142 landraces from a broad geographical range to help elucidate the genetic basis of local adaptation.

143 This work should help elucidate the hydrolytic ring-opening mechanism of

144 ron and high resolution x-ray diffraction to help elucidate the identity of the catalytic base in the

145 The two boundaries help elucidate the in vivo binding structure of a given

146 lity of intermolecular interactions may also help elucidate the interactions of the molecular nanofib

147 These findings help elucidate the link between compulsive eating and an

148 els that develop dysplasia and neoplasia may help elucidate the link between inflammation and colorec

149 y of selective pressures on individuals will help elucidate the maintenance of microbial diversity an

150 ns ubiquitous in key cellular processes, and help elucidate the mechanism and pathological significan

151 ng a catalytic intermediate that promises to help elucidate the mechanism of catalysis.

152 ribution and evolution of these sites and to help elucidate the mechanism of frameshifting, we determ

153 KvDMR1 into its functional components should help elucidate the mechanism of its function in vivo.

154 pendent biological activities of PDNF should help elucidate the mechanism of PDNF activation of TrkA-

155 Our study provides new data that will help elucidate the mechanism of PM10-mediated lung cance

156 To help elucidate the mechanism of protein inactivation med

157 ponse induced by the vaccine have promise to help elucidate the mechanism of SAEs.

158 define the role of OTT1 in hematopoiesis and help elucidate the mechanism of t(1,22) acute megakaryoc

159 ork was to obtain new information that might help elucidate the mechanism of T2 distribution in muscl

160 These findings may help elucidate the mechanism underlying arterivirus repl

161 ion of these findings in further studies may help elucidate the mechanisms behind this short-term inc

162 To help elucidate the mechanisms behind XMRV infection, we

163 APOL1 may provide clues that will ultimately help elucidate the mechanisms by which APOL1 variants pr

164 expression in response to E2F-1 in order to help elucidate the mechanisms by which E2F-1 causes apop

165 ow mutant TBP mediates neuropathology should help elucidate the mechanisms by which transcriptional d

166 To help elucidate the mechanisms involved in the block in p

167 pattern of T cell differentiation that might help elucidate the mechanisms of HCV immunity and pathog

168 ering protective genetic variants that could help elucidate the mechanisms of Mendelian diseases and

169 SA signaling network in plants, and may also help elucidate the mechanisms through which SA acts as a

170 We anticipate that these findings will help elucidate the mechanisms underlying HCM development

171 epts and simplifying modeling approaches may help elucidate the mechanisms underlying other cellular

172 To help elucidate the mechanisms underlying this phenomenon

173 fold and unfold, have recently been used to help elucidate the mechanistic principles that underlie

174 residues at the inhibitor-binding site will help elucidate the molecular basis for fusion activation

175 crystal structures and enzymological studies help elucidate the molecular basis of LovC specificity,

176 aspartate-prone proteins identified here may help elucidate the molecular basis of one or more develo

177 transcriptional regulatory sites in vivo to help elucidate the molecular basis of sex-related differ

178 Expression profiling of pure DCIS will help elucidate the molecular characteristics that distin

179 al outcome of a mutation, and can be used to help elucidate the molecular mechanism of disease/cancer

180 Our findings help elucidate the molecular mechanisms by which transcr

181 These models also help elucidate the molecular mechanisms of corneal epith

182 Identification of the causal alleles will help elucidate the molecular mechanisms responsible for

183 ypoparathyroidism-associated GCMB mutations, help elucidate the molecular mechanisms underlying DNA-b

184 tionary success of the ssDNA viruses and may help elucidate the mystery of integrated RNA viruses in

185 and functional ortholog of mammalian MCH and help elucidate the nature of MCH evolution among vertebr

186 lysis of intrinsic connectivity networks may help elucidate the neural architectures that support fun

187 These findings help elucidate the neural systems-level effects of methy

188 s of OT and OTR in social recognition should help elucidate the neurobiological bases of human disord

189 k towards postmortem human brain research to help elucidate the neurobiological underpinnings of MRI

190 These results not only help elucidate the origins of the TM(n+):TiO(2) DMS ferr

191 Our findings help elucidate the paracrine signaling events activated

192 rther characterization of Vitamin D/VDR will help elucidate the pathogenesis of various human disease

193 The double-mutant mice will help elucidate the pathophysiological mechanisms underly

194 novel mouse model of BONJ-like disease will help elucidate the pathophysiology of BONJ and ultimatel

195 choroidal vasculature at variable depths may help elucidate the pathophysiology of disease and can co

196 chronic inflammatory disease models that can help elucidate the pathophysiology of vascular inflammat

197 sensitive detection of CCC DNA, which should help elucidate the pathways of CCC DNA formation and the

198 and temporal resolution in intact organs may help elucidate the players involved.

199 ion in this model of open-angle glaucoma may help elucidate the primary changes occurring at the mole

200 ormational effects, the study of which might help elucidate the proton-coupled electron-transfer mech

201 s pave the way for further investigations to help elucidate the relationships between telomere length

202 s of neonatal Kiss1 and ERs mRNA levels will help elucidate the relative roles each plays in the sex-

203 he H5N1 isolates from different countries to help elucidate the risk of a human pandemic from the str

204 ease and suggest research avenues that might help elucidate the role of activated platelets in CF.

205 Controlled clinical trials now underway will help elucidate the role of AVP receptor antagonism in th

206 echanisms of microRNA transcription, and can help elucidate the role of microRNA as mediators of comp

207 e and host-microbe chemical cross-talk would help elucidate the role of our gut microbiota in health

208 he Cu-induced transcriptome generated should help elucidate the role of the Cu response in maintainin

209 ties influence the metabolic environment may help elucidate the role of the microbiota in disease dev

210 eloped based on binding domain structures to help elucidate the role of this enzyme in the central ne

211 This strategy is poised to help elucidate the role of variants at the low end of th

212 is mouse model provides a powerful system to help elucidate the specific metabolic mechanisms that un

213 cyclin degradation that we report here could help elucidate the specific roles of the redundant CDK-c

214 The results help elucidate the structural origins of the extreme ant

215 campus, and provides a promising approach to help elucidate the synaptic basis of long-term memory.

216 temporally distinct, and this difference may help elucidate the therapeutic window for use of antivir

217 le probes to the DAT protein will ultimately help elucidate the three-dimensional arrangement of the

218 EYA-SO targets identified in this study will help elucidate the transcriptional circuitries whereby o

219 or a broad array of imaging applications and help elucidate the underlying biologic processes relevan

220 known functional information into GWASs can help elucidate the underlying biological mechanisms and

221 eeded in these secondary forms of disease to help elucidate the underlying cause and pathogenesis of

222 nd understanding their normal functions will help elucidate the underlying causes of these disorders.

223 discoveries with psychological processes and help elucidate the underlying neural mechanisms.

224 We propose a mathematical model that may help elucidate the underlying physiological mechanism re

225 mplications for arbovirus evolution and will help elucidate the viral factors responsible for the bro

226 This new strategy should help to elucidate the biological implications of deamida

227 using cellular systems and animal models can help to elucidate the biological mechanisms involved in

228 with traditional analyses of diagnosis, may help to elucidate the biological pathways underlying fam

229 This observation may help to elucidate the branch point of TGFbeta signaling

230 ced pluripotent stem cells could potentially help to elucidate the complex mechanisms of the disease

231 d signaling ligands such as amino acids will help to elucidate the complex roles of these small molec

232 genomic tool-kit present in Urbilateria will help to elucidate the contribution of gene loss and deve

233 This distinction might help to elucidate the delayed action of antidepressants.

234 eveloped a novel mouse model of PBC that may help to elucidate the detailed mechanism of this complex

235 meric terminal domain complex model may also help to elucidate the effects of mutations in the end do

236 chools by race/ethnicity, sex, and grade may help to elucidate the etiology of childhood overweight a

237 ogous functions of POMT genes in mammals and help to elucidate the etiology of neurological defects i

238 that functional aspects of allelic diversity help to elucidate the evolution of polymorphic genes inv

239 ral history of speciation genomics that will help to elucidate the factors responsible for population

240 protein features were identified which could help to elucidate the function of TM6SF2.

241 These new findings will help to elucidate the genetic program that promotes the

242 To obtain further information that might help to elucidate the mechanism and preferred substrate

243 Our results help to elucidate the mechanism by which somatic-cell nu

244 These data will help to elucidate the mechanism of cross-species infecti

245 corticoid-induced and -repressed genes could help to elucidate the mechanism of GR regulation for the

246 To help to elucidate the mechanism of infection, we have us

247 These findings may help to elucidate the mechanism of the bleeding disturba

248 Our findings help to elucidate the mechanism of thrombus growth and p

249 These results help to elucidate the mechanisms by which Wolbachia adap

250 ts also suggest several experiments that can help to elucidate the mechanisms of in vitro and in vivo

251 r results imply several experiments that can help to elucidate the mechanisms of in vitro and in vivo

252 h respect to protein interactions, which may help to elucidate the mechanisms of ligand discriminatio

253 Here we review recent findings that help to elucidate the mechanisms underlying monogenic an

254 HPS etiology, and further investigations may help to elucidate the mechanisms underlying the observed

255 better understanding of TG2 regulation could help to elucidate the mechanistic basis of this malady.

256 Our results help to elucidate the molecular basis of voltage sensing

257 er development of single-molecule tools will help to elucidate the molecular dynamics of these comple

258 These findings help to elucidate the molecular mechanisms of maspin and

259 This mouse model may help to elucidate the molecular mechanisms that lead to

260 angiosperm flowers and gymnosperm cones may help to elucidate the mysterious origin of the flower.

261 as produced a theoretical framework that can help to elucidate the neural correlates for reward funct

262 rocedures providing full body-based cues may help to elucidate the neural mechanisms supporting spati

263 btained in pentane and computational studies help to elucidate the observed behavior.

264 Ongoing clinical trials will help to elucidate the optimum management of patients wit

265 Understanding epigenetic changes in HCC will help to elucidate the pathogenesis and may eventually le

266 These findings may help to elucidate the pathogenesis of aniridic keratopat

267 in identifying genetic risk factors that can help to elucidate the pathophysiology and that might res

268 ht on the molecular neurobiology of T2DM and help to elucidate the pathophysiology of diabetes-relate

269 onal assessment of new Nav1.9 mutations will help to elucidate the phenotypic spectrum of Nav1.9 chan

270 tools, such as the geriatric assessment, may help to elucidate the physiologic age of the patient as

271 analysis of cell-derived microparticles will help to elucidate the precise mechanisms of their genera

272 egulation of these presynaptic proteins will help to elucidate the presynaptic differentiation proces

273 Our observations help to elucidate the process by which mitogens up-regul

274 DFT calculations help to elucidate the reaction mechanism.

275 Our results help to elucidate the requirements for scaling the metho

276 These electrophysiological studies help to elucidate the role of specific channels in setti

277 igations in humans and in animal models will help to elucidate the role of this enzyme in human disea

278 Further study of such inhibitors may help to elucidate the role played by DC-SIGN in HIV tran

279 describe patterns of sauropod movement will help to elucidate the role that migration played in the

280 ial pyruvate carrier (MPC) inhibitor and may help to elucidate the roles of MPC in amino acid metabol

281 Collectively, our results help to elucidate the roles of PARP-1 in the regulation

282 sistent with available experimental data and help to elucidate the selectivity filters in the Mg(2+)-

283 metics with simple amphiphilic sequences can help to elucidate the structures of cross beta-sheet ass

284 tanding of their underlying mechanisms might help to elucidate the transition of normal physiological

285 de new, robust mouse models of DN and should help to elucidate the underlying genetic basis of predis

286 o independent biochemical pathways that will help to elucidate the underlying pathology.

287 hem into chemically meaningful fragments can help elucidate their functional properties, and may be u

288 Genetic association studies may help elucidate their origin and function.

289 ties of pesticide exposure, they nonetheless help elucidate their risks to colony health.

290 e the study of trace metals in the brain and help to elucidate their role in neurobiology.

291 To help elucidate these roles, we have characterized the fi

292 To help elucidate this process, we examined the binding act

293 To help to elucidate this issue, we applied an in vitro amp

294 ng a set of microarray samples as input, can help elucidate tightly coexpressed gene sets (modules) t

295 cation of changes most specific to HFpEF may help elucidate underlying pathophysiology.

296 annotation of the mammalian genome that will help elucidate various human disease genes and pathways.

297 tional redundancy for Drpr in Drosophila may help elucidate whether paralogs of MEGF10 in humans (eg,

298 contacts than from drinking water, which may help elucidate why interventions focused on water withou

299 ell compartments uniquely place zebrafish to help elucidate why mammals possess such low capacity to

300 Thus, these simulations also help elucidate why some inhibitory serpin families are m