ライフサイエンスコーパス: helper T-cell

1 molecule CD28 is essential for activation of helper T cells.

2 d T cells, especially in the TH17 lineage of helper T cells.

3 he development of IL-17-producing pathogenic helper T cells.

4 or typically expressed by the TH17 subset of helper T cells.

5 -)Sirpalpha(+) DCs induced the TH1 subset of helper T cells.

6 ity to differentiate into the TH17 subset of helper T cells.

7 chanism did not appear to be shared by mouse helper T cells.

8 in controlling the proallergic generation of helper T cells.

9 ferentiation into the TH2 and TH9 subsets of helper T cells.

10 phabeta(+) cytotoxic T lymphocytes or CD4(+) helper T cells.

11 ediated functional differentiation of CD4(+) helper T cells.

12 ewildering number of fates seem possible for helper T cells.

13 tion ex vivo by LN CD4(+)CXCR5(+) follicular helper T cells.

14 on of inducible T(reg) cells into follicular helper T cells.

15 hich occurs almost exclusively in follicular helper T cells.

16 the differentiation of the T(H)17 subset of helper T cells.

17 being activated and in the function of these helper T cells.

18 hat can fine-tune the plasticity and fate of helper T cells.

19 augmented the response by activating CD4(+) helper T cells.

20 ification, differentiation and commitment of helper T cells.

21 mportant regulator of the differentiation of helper T cells.

22 nature cytokines secreted by IL-17-producing helper T cells.

23 es, especially those of the T(H)17 subset of helper T cells.

24 ne profile favoring the generation of Type 1 helper T cells.

25 e network controlling the differentiation of helper T cells.

26 4, which allowed stable expression of Cd4 in helper T cells.

27 ter B cell support by PG-specific follicular helper T cells.

28 tokine produced by regulatory T-cells and by helper T-cells.

29 uggesting a large pool of S. aureus-reactive helper T-cells.

30 ncreases proliferation of cytotoxic, but not helper, T cells.

31 autoimmune diseases through differentiating helper T cell 1 (TH1) and maintaining TH17 responses.

32 F-alpha ratio and suppressed proinflammatory helper T cell 1 (Th1) cytokine expression by autologous

33 wn-regulated pathogenic pro-inflammatory and helper T cell 1 (Th1) responses and up-regulated benefic

34 IV) disease progression is associated with a helper T cell 1 (Th1) to helper T cell 2 (Th2) cytokine

35 rmine whether blockade of the interleukin 23-helper T cell 17 (IL-23-TH17) pathway with ustekinumab r

36 s associated with a helper T cell 1 (Th1) to helper T cell 2 (Th2) cytokine profile switch.

37 n particular, nicotine is found to promote a helper T cell 2 adaptive immunologic response within T c

38 FIV employs a distinct strategy to target helper T cells; a high affinity interaction with CD134 (

39 Helper T-cell activation generally requires the corecept

40 f CD4(-)CD8(+) (cytotoxic) and CD4(+)CD8(+) (helper) T cells, after in vitro re-stimulation.

41 tipeptide vaccine (6MHP), designed to induce helper T cells against melanocytic and cancer-testis ant

42 T-B zone interface and promote induction of helper T cell and antibody responses.

43 ecular interactions at the interface between helper T cells and antigen-presenting B cells govern the

44 reased frequencies of tumor-infiltrating CD4 helper T cells and CD8 memory cytotoxic T cells.

45 ir differentiation into the T(H)17 subset of helper T cells and colitogenic potential, in a manner de

46 CD4+ helper T cells and cytotoxic CD8+ T cells are key player

47 hyperactive response of the T(H)17 subset of helper T cells and developed spontaneous IL-22-dependent

48 mechanisms that regulate the T(H)9 subset of helper T cells and diseases mediated by T(H)9 cells rema

49 regulatory T cells and the T(H)17 subset of helper T cells and diverted CD4(+)Foxp3(-) T cells to a

50 function, amplified the number of follicular helper T cells and germinal-center B cells and plasmabla

51 rs and functionality of LCMV-specific CD4(+) helper T cells and impaired antiviral CD8(+) T-cell resp

52 is produced by cells of the T(H)17 subset of helper T cells and other leukocytes, not only enhances p

53 ed genes, increased the number of follicular helper T cells and plasmablasts in the spleen, and led t

54 ffector cells of the TH1 and TH17 subsets of helper T cells and the development of experimental autoi

55 ed differentiation into the T(H)17 subset of helper T cells and therefore represents a factor that ca

56 is essential for the formation of follicular helper T cells and thus GCs, although whether IRF4 plays

57 ene expression specific to the TH2 subset of helper T cells and was important for the migration of TH

58 ting immune activation was assessed based on helper T-cell and regulatory T-cell activation in mice.

59 mediated by CD4(+)CXCR5(+)PD-1(+) follicular helper T cells, and can suppress inflammation in autoimm

60 renal allograft rejection induced by memory helper T cells, and CD8 T cell depletion at the time of

61 regulatory T cells (Treg), exhausted CD4(+) helper T cells, and myeloid-derived suppressor cells (MD

62 acilitated antigen-specific interaction with helper T cells, and promoted antibody affinity maturatio

63 he generation of antigen-specific follicular helper T cells, antigen-specific GC B cells, and high-af

64 CD4 helper T cells are critical for proper immune cell homeo

65 Helper T cells are critical for protective immunity, CD8

66 echanisms that maintain lineage integrity of helper T cells are largely unknown.

67 roles in the differentiation and function of helper T cells are not well understood.

68 Thus, distinct CD4(+) helper T cells are specialized to help either in primary

69 TH17 cells (interleukin-17 (IL-17)-producing helper T cells) are highly proinflammatory cells that ar

70 unctional antibody responses, via follicular helper T cells, as well as on the roles of CD4(+) T cell

71 ity complex (MHC) class II-restricted CD4(+) helper T cells but are also a common feature of MHC clas

72 class II complexes and defective priming of helper T cells but not of cytotoxic T lymphocyte (CTL) r

73 bility (MHC) class II complexes to stimulate helper T cells, but the genetic and regulatory basis for

74 Alloreactive memory helper T cells can induce potent alloantibody responses

75 , interleukin-12, and subsequent circulation helper T cell (CD4-expressing cells) numbers.

76 ls (CD3(+)), cytotoxic T cells (CD8(+)), and helper T cells (CD4(+)) in vessels of idiopathic PAH lun

77 Helper T cells control host defense against pathogens.

78 ggerated airway eosinophilia, release type 2 helper T cell cytokines and exhibit airway hyper-respons

79 unctions of IL-9 in the regulation of type 2 helper T cell cytokines and responses.

80 findings demonstrate that individual type 17 helper T-cell cytokines can have proinflammatory or anti

81 Type 17 helper T-cell cytokines have been implicated in the path

82 y a reduced expression of both types 1 and 2 helper T-cell cytokines.

83 ia, yet the mechanism by which HIV-1 induces helper T-cell death has not been defined.

84 fibroblasts resulted in impaired follicular helper T cell differentiation and, consequently, in redu

85 Thus, IL-2 influences helper T cell differentiation by modulating the expressi

86 se results demonstrate that miR-29 regulates helper T cell differentiation by repressing multiple tar

87 ondary complications and a skewed follicular helper T-cell differentiation in defined monogenic immun

88 How MyD88 regulates helper T-cell differentiation remains largely unknown, h

89 d, Nlrp10(-/-) mice had a profound defect in helper T-cell-driven immune responses to a diverse array

90 iRNA down-regulation promotes acquisition of helper T cell effector functions by relaxing the repress

91 ller cells (consisting of cytotoxic T cells, helper T cells, effector B cells, and natural killer cel

92 ht zone phenotype (site of Ag and follicular helper T cell encounter) express much higher levels of G

93 xpressed at functionally relevant amounts in helper T cells, Eomes was abundant in miRNA-deficient ce

94 Helper T-cell epitope dominance in human immunodeficienc

95 Using human cells, we identified eight helper T-cell epitopes in PE38, a portion of the bacteri

96 n processing and MHC protein binding for all helper T-cell epitopes of an antigen.

97 opment of innate-like T-cells and follicular helper T-cells, events that are known to require strong/

98 MicroRNA (miRNA)-deficient helper T cells exhibit abnormal IFN-gamma production and

99 Here we found that the helper T cell fate was not fixed and that mature, antige

100 fferentiation is a major determinant for the helper T cell fate.

101 ility of this idea to the T(H)2 cell, T(H)17 helper T cell, follicular helper T cell (T(FH) cell) and

102 Our study highlights the critical role helper T cell function has in the elicitation of broadly

103 ulin class switching is due to deficient CD4 helper T cell function.

104 ter understanding of the mechanisms by which helper T cells function in the natural history of cholan

105 Follicular helper T cells, germinal center B cells, and autoantibod

106 Finally, in NSTEMI patients, helper T cells had a reduced ability in T-cell receptor-

107 Type 17 helper T cells have been suggested to play a pathologica

108 which were implicated in Treg and follicular helper T cell homeostasis.

109 (Tfh) cells comprise an important subset of helper T cells; however, their relationship with other h

110 mock-infected AMs or LMVECs and analyzed for helper T cell (i.e., Treg, Th17, Th1, and Th2) marker ex

111 phages, reminiscent of the licensing role of helper T cells in antiviral adaptive immunity.

112 anti-fungal responses of the TH17 subset of helper T cells in controlling infection with Candida alb

113 ut the differentiation of pathogenic type 17 helper T cells in experimental autoimmune uveoretinitis

114 that endogenous cells of the TH17 subset of helper T cells in lymphoid organs of naive mice 'prefere

115 ion, mature B cells interact with follicular helper T cells in specialized structures called germinal

116 ed and presented by GC B cells to follicular helper T cells in the light zone.

117 accumulated as cells of the T(H)17 subset of helper T cells in the lungs.

118 ine deaminase, and IL-21(+)PD1(+) follicular helper T cells in tLTs together with CD138(+) plasma cel

119 for proper differentiation of types 1 and 2 helper T cells in vivo by restraining the expression and

120 r better showed greater maximum effector and helper T-cell increases, elevated antiviral and alloreac

121 +) T cells and amplifying Th2 and follicular helper T cell induction.

122 Itch deficiency in the TH17 subset of helper T cells, innate lymphoid cells and gammadelta T c

123 The differentiation of helper T cells into effector subsets is critical to host

124 that drive the differentiation of human CD4+ helper T cells into TFH cells remain largely undefined.

125 ifferentiation of the TH1 and TFH subsets of helper T cells is not well understood.

126 induced expression of FcgammaRIIIa on CD4(+) helper T-cells is an important finding since these recep

127 g cells) and the inflammatory TH17 subset of helper T cells leads to the development of autoimmune an

128 Once differentiated, helper T cells maintain a stable transcriptional memory

129 A4, identifying neuropilin-1 (NRP1); and the helper T cell marker, CD4.

130 by key transcription factors, including the helper T cell master regulator ThPOK, which suppresses t

131 ts targeting mechanisms involving CD4 type 1 helper T cells may provide more effective, better tolera

132 ell (Treg) subset that suppresses follicular helper T cell-mediated B cell responses in the germinal

133 essive interferon-gamma that directly limits helper T cell-mediated support of humoral immunity and d

134 and atopic dermatitis, which are both type 2 helper T-cell-mediated diseases.

135 hare common characteristics including type 2 helper-T-cell-mediated inflammation.

136 ry T cells and lymph node-derived follicular helper T cells of patients with CVID compared with those

137 nd of coreceptors through which signals from helper T cells or pathogen-associated molecular patterns

138 e differentiation and function of follicular helper T cells or that of other helper T cell subsets.

139 on (P = 0.007) and CD25 expression on CD4(+) helper T cells (P = 0.0003) in the activated cord blood

140 on factors do not neatly conform to a simple helper T-cell paradigm.

141 The IL-6/follicular helper T cell pathway is a potential therapeutic target

142 family in the determination of the effector helper T cell phenotype that naive CD4(+) T cells adopt

143 pt predominantly type 1 helper or follicular helper T cell phenotypes in response to bacterial or vir

144 CD4+ helper T cells play an essential role in protection agai

145 CD4(+) helper T cells play crucial roles for host defense and i

146 trates that CD28 persistence is required for helper T cell polarization in response to infection, des

147 ntributed to miRNA-dependent proinflammatory helper T-cell polarization.

148 intenance and/or expansion of the follicular helper T cell population, although it was dispensable fo

149 nalysis we define an alpha4 nAChR expressing helper T-cell population (alpha4(+)CD3(+)CD4(+)) and sho

150 F(+))-producing cells and contain follicular helper T-cell populations not only in the spleen and dra

151 sulted in the post-thymic termination of the helper T cell program and the functional differentiation

152 itory circuit that stabilizes the follicular helper T cell program at least in part through the contr

153 generation of an autoreactive TH17 subset of helper T cells, prominently associated with autoimmune d

154 Thus, the sites of helper T-cell recognition, the dominant epitopes, are ta

155 rs experienced significant downregulation of helper T-cell-related (T(H)1, T(H)17, and T(H)22) mRNA e

156 nt for differentiation of the TH17 subset of helper T cells remain unclear.

157 into the T(H)1, T(H)2 and T(H)17 subsets of helper T cells, respectively.

158 Deer mice remain infected despite a helper T cell response that leads to high-titer neutrali

159 the proteins contribute most strongly to the helper T cell response, highlight specific weaknesses of

160 mice developed an exaggerated type 1 and 17 helper T-cell response, characterized by natural killer

161 in the lungs, associated with poor specific helper T-cell response.

162 erial burdens and changes in the host type 1 helper T-cell response.

163 so required to elicit proinflammatory CD4(+) helper T cell responses to infection and mucosal vaccina

164 MHC class II-restricted T cells and promote helper T cell responses.

165 and other diseases driven by an imbalance in helper T cell responses.

166 s in an impaired ability to stimulate CD4(+) helper T cell responses.

167 iew the current status of the flexibility of helper T-cell responses in relation to their genetic reg

168 ese data suggest that pDCs facilitate CD4(+) helper T-cell responses to persistent viruses independen

169 mmunodeficiency viruses (FIV and HIV) target helper T cells selectively, and in doing so they induce

170 our findings suggest that the TH9 subset of helper T cells serves an important role in driving ulcer

171 rexate is an immunomodulator with effects on helper T-cell signaling in psoriasis.

172 what do terms like 'lineage commitment' and helper T-cell 'specification' mean in the early 21st cen

173 renal allograft rejection induced by memory helper T cells starting at day 4 after transplantation.

174 Each helper T cell subset expresses a distinct set of genes t

175 elper T cells (TFH cells) are the prototypic helper T cell subset specialized to enable B cells to fo

176 FOXP3-positive Treg cells are a critical helper T cell subset, and dysregulation of Treg generati

177 anti-tumor effects of a unique human CD4(+) helper T-cell subset that directly recognizes the cytopl

178 differentiation into at least four distinct helper T cell subsets after recognition of foreign antig

179 ve phenotypes that mirror those of polarized helper T cell subsets in their expression of core transc

180 n RA compared to healthy controls, but other helper T cell subsets were not different.

181 The differentiation of CD4(+) helper T cell subsets with diverse effector functions is

182 e Notch family direct the differentiation of helper T cell subsets, but their influence on regulatory

183 ell progenitors to terminally differentiated helper T cell subsets.

184 f follicular helper T cells or that of other helper T cell subsets.

185 ls, even as they differentiate into effector helper T cell subsets.

186 f signature cytokines, analogous to adaptive helper T cell subsets.

187 ously defined 'master regulators' for CD4(+) helper T-cell subsets are also shared by ILC subsets.

188 t and functional divergence of the different helper T-cell subsets as well as in regulatory T cells.

189 ur appreciation for the actual complexity of helper T-cell subsets continues unabated.

190 We analyzed CD4(+) helper T-cell subsets from peripheral blood or cerebrosp

191 Added to the crowded scene for helper T-cell subsets is the continuously growing family

192 an important regulator of other specialized helper T-cell subsets within germinal centers, pre-germi

193 lammatory diseases thought to be mediated by helper T-cell subtypes 1 and 2 (TH1 and TH2), respective

194 nteresting results include CSF enrichment of helper T cells (subtypes TH1 and TH17) and regulatory T

195 ntiated more readily into cytokine-producing helper T cells, suggesting that activation-induced miRNA

196 T(H)2 cell, T(H)17 helper T cell, follicular helper T cell (T(FH) cell) and induced regulatory T cell

197 lper type 1 cell (T(H)1 cell) and follicular helper T cell (T(FH) cell) gene-expression profile, resp

198 hought be an autocrine factor for follicular helper T cell (T(FH)) and Th17 differentiation.

199 d T(reg) cell-mediated suppression of type 1 helper T cell (T(H)1 cell) responses and protected again

200 CD4(+) follicular helper T cells (T(FH) cells) are essential for germinal

201 Follicular helper T cells (T(FH) cells) are responsible for effecti

202 Follicular helper T cells (T(FH) cells) are specialized effector CD

203 Follicular helper T cells (T(FH) cells) constitute the CD4(+) T cel

204 paralleled by the accumulation of follicular helper T cells (T(FH) cells) is linked to mutation of th

205 Follicular helper T cells (T(FH) cells) provide critical help to B

206 ediated by CD4(+)CXCR5(+)Foxp3(-) follicular helper T cells (T(FH) cells).

207 ich are needed for development of follicular helper T cells (T(FH) cells).

208 cells suppressed CD4 T cells and follicular helper T cells (T(FH)) in a perforin-dependent manner du

209 the expansion of antigen-specific follicular helper T cells (T(fh)), compared to vaccinations with so

210 CD4(+) interleukin 17 (IL-17)-producing helper T cells (T(H)17 cells) are instrumental in the im

211 Interleukin 17 (IL-17)-producing helper T cells (T(H)17 cells) are often present at the s

212 s (T(H)2 cells) and interleukin 17-producing helper T cells (T(H)17 cells) but not of T helper type 1

213 We found that IL-17-producing helper T cells (T(H)17 cells) had distinct plasticity in

214 Interleukin 17-producing helper T cells (T(H)17 cells) have a major role in prote

215 Interleukin 17 (IL-17)-producing helper T cells (T(H)17 cells) require exposure to IL-23

216 In contrast, tissue type 2 helper T cells (T(H)2 cells) produced both cytokines.

217 Given their functional relatedness to type 2 helper T cells (T(H)2 cells), we explored whether Gfi1 a

218 ent of interleukin 4 (IL-4)-producing type 2 helper T cells (T(H)2 cells), which suggests that T(H)2

219 , patients with IMNM exhibit a strong type 1 helper T cell (T1)/classically activated macrophage M1 r

220 tches, such TH17 cells acquired a follicular helper T cell (TFH cell) phenotype and induced the devel

221 pe 1 helper T cell (TH1 cell) and follicular helper T cell (TFH cell) responses.

222 atory T cells (TFR cells) inhibit follicular helper T cell (TFH cell)-mediated antibody production.

223 In contrast, follicular helper T cell (TFH) effectors are generated after primin

224 Follicular helper T cells (Tfh ) are located within germinal center

225 Follicular helper T cells (TFH cells) and follicular regulatory T c

226 Follicular helper T cells (TFH cells) are CD4(+) T cells specialize

227 Follicular helper T cells (Tfh cells) are required for T cell help

228 Follicular helper T cells (Tfh cells) are the major producers of in

229 Follicular helper T cells (TFH cells) are the prototypic helper T c

230 Follicular helper T cells (TFH cells) compose a heterogeneous subse

231 g the developmental mechanisms of follicular helper T cells (TFH cells) in humans is relevant to the

232 Aberrant population expansion of follicular helper T cells (TFH cells) occurs in patients with lupus

233 Within the GC, FO helper T cells (TFH cells) provide a local source of BLy

234 cy virus (HIV), which persists in follicular helper T cells (TFH cells), and Epstein-Barr virus (EBV)

235 g helper T cells (TH17 cells) and follicular helper T cells (TFH cells).

236 pends on interactions with CD4(+) follicular helper T cells (TFH cells).

237 fuels the stepwise development of follicular helper T cells (TFH cells).

238 is is dependent on CD4(+)CXCR5(+) follicular helper T cells (TFH) and inhibited by CD4(+)CXCR5(+)Foxp

239 Follicular helper T cells (Tfh) are essential for B cell production

240 by the more recent definition of follicular helper T cells (Tfh) as the key T cell subset in B cell

241 In follicular lymphoma (FL), follicular helper T cells (TFH) have been depicted as one of the ma

242 Follicular helper T cells (Tfh) have been well documented to play a

243 esponse through interactions with follicular helper T cells (TFH).

244 Follicular helper T cells (TFHs) are a key component of adaptive im

245 ssion also expanded the number of follicular helper T cells (TFHs) in a cell-intrinsic and Ag-specifi

246 the normal balance of pneumococcal-specific helper T cell (Th) 1/Th17 immunity to colonization, resu

247 -based vaccine formulation enhances systemic helper T cells TH1 and TH2 serum antibody and cytotoxic

248 Treg cell stability to repression of type 1 helper T cell (TH1 cell) and follicular helper T cell (T

249 between groups were observed for the type 1 helper T cell (TH1)-associated chemokines CXCL9 and CXCL

250 rosis factor-alpha; decreased types 1 and 17 helper T cells (Th1 and Th17, respectively); and increas

251 uding Slc2a1, Slc2a3, Pkm and Hk2, in type 1 helper T cells (TH1 cells) exposed to low concentrations

252 r the signaling pathways of type 1, 2 and 17 helper T cells (TH1, TH2 and TH17), JAK-STAT, interferon

253 naling, induces the expression of the type 1 helper T-cell (Th1) cytokine, interferon gamma, and supp

254 negative Borrelia cultures, and the type 17 helper T cell (TH17)-associated cytokine interleukin 23

255 Interleukin 17 (IL-17)-producing helper T cells (TH17 cells) and CD4(+) inducible regulat

256 ntiation of interleukin 17 (IL-17)-producing helper T cells (TH17 cells) and follicular helper T cell

257 Interleukin (IL) 17-secreting CD4(+) helper T cells (Th17 cells) are essential for host defen

258 tion of interleukin (IL)-17-producing CD4(+) helper T cells (TH17 cells) has a pivotal role in autoim

259 mediated by interleukin 17 (IL-17)-producing helper T cells (TH17 cells) in the peripheral immune and

260 IL-17-producing CD4 helper T cells (Th17 cells) play a critical role in prom

261 recently discovered interleukin-17 producing helper T cells (Th17), which are fundamental for anti-mi

262 A-regulated pathways that control the type 2 helper T cell (TH2 cell) responses that drive pathogenic

263 bl deficiency skews CD4(+) T cells to type 2 helper T cell (Th2) differentiation, and c-Abl(-/-) mice

264 Multiple exposure to type 2 helper T cell (Th2)-inducing stimuli further enhances bo

265 The role of the type 2 helper T cell (Th2)-polarizing cytokines IL-4 and IL-10

266 ated inflammation that is driven by a type 2 helper T cell (Th2).

267 ate lymphoid cells (ILC2s) and CD4(+) type 2 helper T cells (TH2 cells) are defined by their similar

268 p 2 innate lymphoid cells (ILC2s) and type 2 helper T cells (Th2 cells) are the primary source of int

269 interleukin-33 (IL-33), which induces type-2 helper T cells (Th2 cells) at the site of infection to p

270 Type 2 helper T cells (TH2 cells) produce interleukin 13 (IL-13

271 lymphoid cells (ILC2s) and recruited type 2 helper T cells (TH2 cells).

272 with increased levels of eotaxins and type 2 helper T-cell (Th2) cytokines as disease progressed and

273 re prespecified according to baseline type 2 helper T-cell (Th2) status (assessed on the basis of tot

274 Effects on various type 2 helper T-cell (Th2)-associated biomarkers and safety and

275 by dupilumab of these key drivers of type 2 helper T-cell (Th2)-mediated inflammation could help in

276 the differentiation of CD4(+) IL-9-producing helper T cells (TH9 cells) remain incompletely understoo

277 y which a B cell is optimally activated by a helper T cell that responds to the same, or physically a

278 cells, promoting their differentiation into helper T cells that coordinate immune responses.

279 ility complex (MHC) class II-selected CD4(+) helper T cells that expressed CD8-lineage genes such as

280 dependent skin inflammation driven by CD4(+) helper T cells that produced the cytokines IL-17 and IL-

281 Unlike other helper T cells, the costimulatory ligands responsible fo

282 ate that they are not equivalent for CD4(+) 'helper' T cells, the principal orchestrators of adaptive

283 atory disease driven by the T(H)17 subset of helper T cells through molecular mechanisms that remain

284 ulates differentiation of the TH17 subset of helper T cells, thymic T cell development and lymph-node

285 coordinates signals derived from innate and helper T cells to control the production of a regulatory

286 The discovery of the specification of CD4(+) helper T cells to discrete effector 'lineages' represent

287 the expression of genes in the TH2 subset of helper T cells to enhancer occupancy by the BATF-IRF4 tr

288 In multimarker analysis, the helper T cell type 1 (TH1)-related markers interferon-ga

289 IL-13, a helper T cell type 2 (Th2) cytokine, transforms cultured

290 L-5 circumsporozoite protein (CSP) ratios, a helper T cell type 2 cytokine, correlated with higher od

291 s, highlighting the underappreciated role of helper T-cell type 2-related pathways.

292 t mRNA level ratio, consistent with a type 2 helper T-cell-type inflammatory response, and subacute f

293 modes of antigen presentation and priming of helper T cell versus CTL responses.

294 292, enhancing T-cell activation, in NSTEMI helper T cells versus SA and controls (each, p < 0.001),

295 toimmunity and regarded as "extrafollicular" helper T cells, were rare throughout the response, despi

296 ibodies require help from other lymphocytes (helper T cells) which recognize small peptides derived f

297 F) gene (Batf(-/-)) lack TH17 and follicular helper T cells, which demonstrates that Batf is a transc

298 ls and CD4(+) Th cells, including follicular helper T cells, which resulted in high titers of anti-nu

299 103(+) DC subsets induced the TH17 subset of helper T cells, while CD103(-)Sirpalpha(+) DCs induced t

300 thogen containment to the differentiation of helper T cells, yet the cues that position cells in this