ライフサイエンスコーパス: hemangioma

1 (rhabdomyoma, myxoma, teratoma, fibroma, and hemangioma).

2 eins (metastasis) and disrupts blood supply (hemangiomas).

3 nly confronted with the problem of a growing hemangioma.

4 re treated for symptomatic papillary retinal hemangioma.

5 system was searched in a 10-year period for hemangioma.

6 valuation and treatment of CMN and infantile hemangioma.

7 To describe OCTA features of iris racemose hemangioma.

8 ticipants had a clinically visible choroidal hemangioma.

9 46 were classified as benign foci other than hemangioma.

10 onchopulmonary aspergillosis, and subglottic hemangioma.

11 ure standard-of-care treatment for infantile hemangioma.

12 stemic use of propranolol to treat infantile hemangioma.

13 atments for periocular infantile (capillary) hemangioma.

14 ve been used to successfully treat infantile hemangioma.

15 l of stem cells derived from human infantile hemangioma.

16 osin, immunodiagnostic markers for infantile hemangioma.

17 th is a rare and atypical feature of hepatic hemangioma.

18 /- and Tsc2+/- mice frequently develop liver hemangioma.

19 ations as the underlying cause of congenital hemangioma.

20 depicts the looping course of iris racemose hemangioma.

21 om patients undergoing resection for hepatic hemangioma.

22 a hemangiomatosis presentation of congenital hemangioma.

23 bnormal vessel growth typical of epithelioid hemangioma.

24 y for 6 months in the treatment of infantile hemangioma.

25 esion which had a classic imaging pattern of hemangioma.

26 data describe the natural history of hepatic hemangiomas.

27 nevi, nevus sebaceus, port-wine stains, and hemangiomas.

28 ful tool in the assessment of possible liver hemangiomas.

29 of benign vascular tumors such as infantile hemangiomas.

30 the treatment of certain types of infantile hemangiomas.

31 y for the treatment of complicated infantile hemangiomas.

32 mangiomas and treating complicated infantile hemangiomas.

33 on of propranolol on regression of infantile hemangiomas.

34 the formation and rapid growth of infantile hemangiomas.

35 (IGFBP3) was down-regulated in proliferating hemangiomas.

36 ular tumorigenesis in a mouse model of liver hemangiomas.

37 by the growth of abnormal blood vessels and hemangiomas.

38 s that expressed high levels of VEGF induced hemangiomas.

39 ations, juvenile angiofibromas and infantile hemangiomas.

40 of MET and contribute to the development of hemangiomas.

41 anscription factors Snail/Slug in involuting hemangiomas.

42 epartment as either typical or suspicious of hemangioma 1.5-4 years earlier were enrolled in this ret

43 hree types of liver lesions (13 cysts, seven hemangiomas, 10 metastases) were selected.

44 ad focal nodular hyperplasia, 25 (17.0%) had hemangiomas, 11 (7.5%) had hepatic epithelioid hemangioe

45 USG findings were categorized as (1) cyst or hemangioma, (2) indeterminate lesion, (3) suspicious for

46 lipoma (5%), lymphangioma (3%) and capillary hemangioma (3%).

47 17 patients with eyelid infantile capillary hemangiomas, 3 were excluded for asthma and 14 (7 males,

48 ses, 7 basal cell carcinomas, 7 melanomas, 4 hemangiomas, 4 dermatofibromas, 2 squamous cell carcinom

49 dded (FFPE) congenital cutaneous and hepatic hemangiomas, 4/8 had GNAQ or GNA11 Glu209 variants.

50 ecimens of venous malformations, 4 capillary hemangiomas, 7 lymphatic malformations, and 6 lymphatico

51 : To describe the sequelae left by infantile hemangiomas after natural involution and to identify cli

52 (RPE), hemorrhagic RPE detachment, choroidal hemangioma, age-related macular degeneration, RPE hyperp

53 has been used to treat complicated infantile hemangiomas, although data from randomized, controlled t

54 Of the 13 lesions identified as a cyst/hemangioma and 17 as indeterminate, 1 was found to be me

55 n Tsc1+/- female mice, with 91% having liver hemangioma and 55% having severe lesions by 7 months of

56 tem cell as the cellular origin of infantile hemangioma and describes for what we believe is the firs

57 viously described in vivo model of infantile hemangioma and in cultured hemangioma-derived cells.

58 e lesions are shared with those of infantile hemangioma and tufted angioma of children, but features

59 difference in accumulation of RBCs between a hemangioma and uninvolved liver remains unknown.

60 riasis, use of topical timolol for infantile hemangiomas and bone marrow transplantation for dystroph

61 is the association of large segmental facial hemangiomas and congenital anomalies, such as posterior

62 for atopic dermatitis, psoriasis, infantile hemangiomas and dystrophic epidermolysis bullosa are rev

63 t of atopic dermatitis, psoriasis, infantile hemangiomas and dystrophic epidermolysis bullosa will be

64 e quotients of accumulation of Tc-99m-RBC in hemangiomas and in normal liver parenchyma (HEM/liv), an

65 nd show that FoxOs suppress the formation of hemangiomas and lymphomas in mice.

66 ALV-J) is a simple retrovirus that can cause hemangiomas and myeloid tumors in chickens and is curren

67 enes in a VHL mouse model of cavernous liver hemangiomas and polycythemia.

68 ells of the myeloid lineage in proliferating hemangiomas and propose a mechanism for the observed evo

69 Nine hemangiomas and six venous malformations were found amon

70 ndrome (BRRS), characterized by lipomatosis, hemangiomas and speckled penis.

71 ssed the development of VHL-associated liver hemangiomas and that angiogenic gene expression in hepat

72 clinical syndromes associated with infantile hemangiomas and treating complicated infantile hemangiom

73 33(-)/Ulex europeus-I(+)) from proliferating hemangiomas and used a previously described property of

74 ace markers and other cellular properties in hemangiomas and vascular malformations relevant to vascu

75 ations and clinical issues for patients with hemangiomas and vascular malformations, and (4) the eluc

76 The transcriptomes of placenta, hemangioma, and eight normal and diseased tissues were c

77 lular carcinoma, one cholangiocarcinoma, one hemangioma, and one biliary hamartoma).

78 Hepatocellular carcinomas (HCCs), hemangiomas, and adenomas had more variable uptake diffe

79 Atypical presentation and abscess-, hemangioma-, and metastasis-like images delayed AE diagn

80 We found that the Tsc mouse liver hemangioma are composed predominantly of endothelial cel

81 e-related macular degeneration and infantile hemangioma are more common in light-skinned individuals

82 anscriptomes of human placenta and infantile hemangioma are sufficiently similar to suggest a placent

83 Infantile hemangiomas are benign tumors of vascular endothelial ce

84 Infantile hemangiomas are characterized by rapid capillary growth

85 While hemangiomas are classic examples of angiogenesis, the an

86 Hemangiomas are common, and most lesions are benign.

87 genital melanocytic nevi (CMN) and infantile hemangiomas are commonly encountered in newborns and may

88 Infantile hemangiomas are composed of endothelial cells (ECs), end

89 The consequences of hemangiomas are extensive and can be challenging to reco

90 Infantile hemangiomas are localized and rapidly growing regions of

91 Although capillary hemangiomas are more common in children, lobular capilla

92 esis, the angiogenic factors responsible for hemangiomas are not fully understood.

93 Our results indicate that hemangiomas are not microchimeric in origin.

94 Hemangiomas are one of the common primary benign tumors

95 As infantile hemangiomas are reported to express high levels of beta

96 Infantile hemangiomas are the most common benign tumors of infancy

97 Hemangiomas are the most common type of tumor in infants

98 Congenital hemangiomas are typically solitary and have not been rep

99 Congenital hemangiomas are uncommon benign vascular tumors that pre

100 isolated from blood or from a proliferating hemangioma, are stimulated by an angiogenesis inhibitor.

101 We hypothesized that congenital hemangiomas arise due to somatic mutation and performed

102 ls (PHACE syndrome--Posterior fossa defects, Hemangiomas, Arterial anomalies, Cardiac defects and Coa

103 diagnosed with periocular lobular capillary hemangioma at a median age of 39 years (range, 17-82 yea

104 All patients with eyelid infantile capillary hemangiomas at risk of developing amblyopia seen between

105 Vertebral hemangiomas being the most common of all are seen in dai

106 ioma of infancy and, using a murine model of hemangioma, bEnd.3 cells; we show that bEnd.3 hemangioma

107 s that Rapamycin also leads to regression of hemangioma blood vessels, consistent with its known anti

108 essed in the endothelium of human tumors and hemangiomas but was undetectable in normal endothelium.

109 teroids are commonly used to treat infantile hemangioma, but the mechanism of action of this therapy

110 e more common in children, lobular capillary hemangiomas can also arise in the periocular region of a

111 irths, and although rarely life threatening, hemangiomas can pose serious concerns to the cosmetic an

112 Although benign, some hemangiomas cause deformation and destruction of feature

113 s this issue, we used tie-2-deficient bEnd.3 hemangioma cells, which, surprisingly, were fully profic

114 Cavernous hemangiomas (CHs) account for 5% to 12% of all spinal va

115 Congenital hemangiomas (CHs) are rare benign vascular tumors that d

116 The average age at which hemangioma completed involution was 3.5 years.

117 (OCTA) allows visualization of iris racemose hemangioma course and its relation to the normal iris mi

118 dition characterized by thymic lymphomas and hemangiomas, demonstrating that the mammalian FoxOs are

119 pression of GFP was used to confirm that the hemangioma-derived cells formed the blood vessels and ad

120 when transplanted into immunodeficient mice, hemangioma-derived cells recapitulated the unique evolut

121 odel of infantile hemangioma and in cultured hemangioma-derived cells.

122 and used a previously described property of hemangioma-derived ECs (HemECs), enhanced migratory acti

123 gioma-derived stem cells in vitro but not by hemangioma-derived endothelial cells or human umbilical-

124 In hemangioma-derived endothelial cells, defects in a vascu

125 Our hypothesis is that hemangioma-derived EPCs (HemEPCs) differentiate into the

126 ioma-genesis we characterized the progenitor hemangioma-derived stem cell (HemSC) and its lineage and

127 on its ability to inhibit proliferation of a hemangioma-derived stem cell population, human vasculoge

128 We also tested hemangioma-derived stem cells for expression of vascular

129 We tested hemangioma-derived stem cells for vasculogenic activity

130 Pretreatment of hemangioma-derived stem cells in vitro before implantati

131 examethasone suppressed VEGF-A production by hemangioma-derived stem cells in vitro but not by hemang

132 Silencing VEGF-A in hemangioma-derived stem cells reduced vasculogenesis in

133 d also inhibited the expression of VEGF-A by hemangioma-derived stem cells, and silencing of VEGF-A e

134 nt suppressed other proangiogenic factors in hemangioma-derived stem cells, including urokinase plasm

135 redefining the clinical course of infantile hemangiomas, describing clinical syndromes associated wi

136 is known about the pathogenesis of infantile hemangiomas despite the fact that they are relatively co

137 logic means, suggesting that angiogenesis in hemangiomas differs fundamentally from that of malignant

138 Although most CMN and infantile hemangiomas do not require active intervention, understa

139 ry as a basis, we set out to explore whether hemangioma endothelial cells (HEC) were maternal in orig

140 thelial growth factor receptor-1 (VEGFR1) in hemangioma endothelial cells (hemECs) and hemangioma tis

141 As a consequence, hemangioma endothelial cells exhibit constitutive vascul

142 Cultured proliferating and involuting hemangioma endothelial cells were treated with varying c

143 led to a dose dependent cytotoxic effect in hemangioma endothelial cells with decreased cell viabili

144 32, CD14, CD15) that unexpectedly co-labeled hemangioma endothelial cells, providing new evidence tha

145 ranscriptome similarity between placenta and hemangioma exceeded that of any other tissue compared an

146 tal cavernous venous malformations (not true hemangiomas), except that their vascular walls are thinn

147 s support a unifying diagnosis of congenital hemangioma for these vascular tumors.

148 es recent studies of molecular mechanisms of hemangioma formation and places new findings and hypothe

149 therapy for problematic hemangioma, to block hemangioma formation in vivo.

150 ngioma specimens, raise the possibility that hemangioma formation involves a combination of germline

151 uld be potentially helpful in distinguishing hemangiomas from other RBC-accumulating liver masses.

152 To understand the process of hemangioma-genesis we characterized the progenitor heman

153 During follow-up, 39.3% of hemangiomas grew 5% or more in mean linear dimension.

154 Nearly 40% of hepatic hemangiomas grow over time.

155 establishes Nox4 as a critical regulator of hemangioma growth and identifies fulvenes as a potential

156 Nox activity in vitro and potently inhibited hemangioma growth in vivo.

157 reased Ang2 mRNA levels and greatly impaired hemangioma growth in vivo.

158 th a soluble tie-2 receptor decreases bEnd.3 hemangioma growth in vivo.

159 that this treatment nearly abolished bEnd.3 hemangioma growth in vivo.

160 d subcutaneously into nude mice, we compared hemangioma growth originating from bEnd cells derived fr

161 h production of VEGF was sufficient to cause hemangioma growth.

162 on at a time when the treatment paradigm for hemangiomas has changed.

163 Hemangiomas have been found to be clonal neoplasms of en

164 macrophage-treated ECs isolated from patient hemangiomas (HemECs) but not untreated HemECs readily di

165 ography performed in 1 eye depicted the iris hemangioma; however, small-caliber radial iris vessels w

166 ay) in the treatment of periocular infantile hemangioma (IH) based on clinical and radiological findi

167 Infantile hemangioma (IH) is a common childhood vascular tumor.

168 Infantile hemangioma (IH) is the most common tumor of infancy.

169 Herein, we used infantile hemangioma (IH), the most common tumor of infancy, as a

170 re multipotent cells isolated from infantile hemangioma (IH), which form hemangioma-like lesions when

171 Infantile hemangiomas (IH) are common tumors for which there is no

172 Propranolol therapy for infantile hemangiomas (IH) is now being used widely, and case repo

173 Infantile hemangiomas (IHs) are common benign tumors of infancy th

174 ikely to make a correct diagnosis of SCC and hemangioma in color (P < .001 for both comparisons) and

175 icantly accelerated the development of liver hemangioma in Tsc1+/- female mice, with 91% having liver

176 s tumors that are accompanied by soft tissue hemangiomas in Maffucci syndrome.

177 y active Akt was sufficient to induce benign hemangiomas in mice, whereas heterozyogosity for PTEN (t

178 lar tumors that differ from common infantile hemangiomas in that they grow in utero and are fully dev

179 cantly reduced the frequency and severity of hemangiomas in Tsc1+/- female mice.

180 ly expressed in proliferating and involuting hemangiomas in vivo will contribute to our understanding

181 tion may be useful in the treatment of human hemangiomas in vivo.

182 reason for vertebroplasty was the vertebral hemangioma, in another 4 - pathological vertebral fractu

183 Using an experimental model of human hemangiomas, in which polyoma middle T-transformed brain

184 Conventional treatments for infantile hemangioma include the use of corticosteroids, laser, su

185 Certain clinical characteristics of hemangioma, including those located on the head and neck

186 The mechanisms that trigger involution of hemangioma into fibro-fatty tissue remain unknown.

187 Importance: Infantile hemangiomas involute to some extent, but they often leav

188 Capillary hemangiomas involved the upper eyelid in 10 cases and th

189 Infantile hemangioma is a benign endothelial tumor composed of dis

190 Infantile hemangioma is a common vascular tumor with a unique life

191 Epithelioid hemangioma is a locally aggressive vascular neoplasm, fo

192 Congenital hemangioma is a rare vascular tumor that forms in utero.

193 Synovial hemangioma is benign tumor of the joints and is seen rel

194 er proton beam therapy for retinal papillary hemangioma is convincing, whereas functional outcome may

195 male patient with the diagnosis of synovial hemangioma is reported and its radiologic findings are m

196 ogenic endothelial cells in common infantile hemangioma is unknown.

197 od cells (Tc-99m-RBC) for detection of liver hemangiomas is very high, it is still not perfect.

198 s malformation (VVM), also called "verrucous hemangioma," is a non-hereditary, congenital, vascular a

199 zed the treatment of proliferating infantile hemangiomas, laser and/or surgical excision are useful i

200 omas (KHEs), and childhood lobular capillary hemangiomas (LCHs).

201 l propranolol for eyelid infantile capillary hemangiomas led to complete regression of the lesion in

202 Superficial and deep hemangiomas left significantly fewer sequelae than combi

203 lls from hemangioma tissue that give rise to hemangioma-like lesions in immunodeficient mice.

204 d from infantile hemangioma (IH), which form hemangioma-like lesions when injected subcutaneously int

205 edominantly benign complication in infantile hemangioma, little is known about the prognosis of ulcer

206 most common lesions were renal cysts, liver hemangiomas, liver cysts, thyroid nodules, and uterine l

207 t significantly fewer sequelae than combined hemangiomas (Mann-Whitney; superficial vs deep, OR, 1.6;

208 the unique self-limited growth of infantile hemangioma may, in fact, mirror the lifetime of placenta

209 sically located inside the liver parenchyma, hemangiomas may occasionally develop outside the extra-h

210 2%), Schmorl nodes with edema (mean, 58.0%), hemangiomas (mean, 49.4%), and benign fractures (mean, 4

211 Our in vitro and in vivo (hemangioma model of angiogenesis) experiments confirmed

212 Initial misdiagnosis as retinitis (n = 5), hemangioma (n = 1), choroidal neovascular membrane (n =

213 = 23), cholangiocarcinoma (n = 6), cavernous hemangioma (n = 4), focal nodular hyperplasia (n = 2), h

214 bdomyoma (n = 14), malignant tumor (n = 12), hemangioma (n = 9), thrombus (n = 4), myxoma (n = 3), te

215 ation on surgical specimens of proliferating hemangiomas (n=8) demonstrated no XX-labeled HEC from re

216 stabilizes (i.e., non-involuting congenital hemangioma [NICH]).

217 by Harve Deramond in France in 1984 due to a hemangioma of cervical vertebral body.

218 n of the endothelial tie-2 receptor in human hemangioma of infancy and, using a murine model of heman

219 The morphology and location of a hemangioma of infancy are critically important factors i

220 Hemangioma of infancy is the most common neoplasm of chi

221 Hemangioma of the rib is rarely seen.

222 rteriovenous malformations: one had a benign hemangioma of the small bowel, and the other had chronic

223 (1) the establishment of a relation between hemangiomas of infancy and placental tissue, (2) the dis

224 Hemangiomas of infancy differ from malignant endothelial

225 ry of unique immunohistochemical markers for hemangiomas of infancy, (3) the importance of morphology

226 in nongenital warts, molluscum contagiosum, hemangiomas of infancy, and basal cell carcinoma.

227 ch as infantile atopic dermatitis, vitiligo, hemangiomas of infancy, warts, and molluscum contagiosum

228 found to be effective in treatment of severe hemangiomas of infancy.

229 has led to advances in the understanding of hemangiomas of infancy.

230 Features of iris racemose hemangioma on OCTA.

231 center evaluating the growth rate of hepatic hemangiomas on cross-sectional imaging studies during a

232 These conditions include renal hemangiomas or arteriovenous malformations, ureteropelvi

233 or nearly complete resolution of the target hemangioma) or failure of trial treatment at week 24, as

234 d in children with associated skin capillary hemangioma (p < 0001).

235 wth factor receptor/integrin complex in some hemangioma patients, and somatic mutations in a phosphat

236 rnt completely suppressed the development of hemangiomas, polycythemia, and Hif-induced gene expressi

237 emangioma, bEnd.3 cells; we show that bEnd.3 hemangiomas produce both angiopoietin-2 (ang-2) and its

238 ic C482R VEGFR-2 mutant, linked to infantile hemangioma, promotes ligand-independent signaling by mim

239 ities of the airway, such as laryngomalacia, hemangiomas, pyriform aperture stenosis, choanal atresia

240 s/caregivers completed the 35-item Infantile Hemangioma Quality-of-Life (IH-QoL) instrument and provi

241 induced by M1 macrophages promotes infantile hemangioma regression and may lead to novel therapeutic

242 o-mesenchymal transition (EndMT) and promote hemangioma regression.

243 n part, recapitulated the natural history of hemangioma regression.

244 5 months of age with proliferating infantile hemangioma requiring systemic therapy.

245 s of ulcerated rapidly involuting congenital hemangiomas (RICH) that were complicated by life-threate

246 quickly (i.e., rapidly involuting congenital hemangioma [RICH]) or partially regresses and stabilizes

247 Human placenta and infantile hemangioma samples highly express ECSCR protein, suggest

248 and ocular adnexal tissue, such as lymphoma, hemangioma, sarcoidosis, and dermoid cyst.

249 Spindle cell hemangioma (SCH) is a rare, benign vascular tumor of the

250 rmine how patients with more rapidly growing hemangiomas should be treated.

251 eformations helped to the final diagnosis of hemangioma, showing its origin from the liver edge.

252 VEGF-A was detected in hemangioma specimens in the proliferating phase but not

253 matic mutations in a phosphatase in sporadic hemangioma specimens, raise the possibility that hemangi

254 Hemangioma stem cells (HemSCs) are multipotent cells iso

255 ng of blood flow through vessels formed with hemangioma stem cells shows that Rapamycin also leads to

256 differentiation potential in patient-derived hemangioma stem cells, and suggests a novel therapeutic

257 cin reduces the self-renewal capacity of the hemangioma stem cells, diminishes differentiation potent

258 egrations in the MET gene in two of the five hemangiomas studied.

259 ary outcomes include the fraction of hepatic hemangiomas that demonstrated growth during long-term fo

260 Although the overall rate of growth is slow, hemangiomas that exhibit growth do so at a modest rate (

261 ve cohort study of images from 187 infantile hemangiomas that had not received systemic treatment and

262 Most are benign infantile hemangiomas that typically regress by 5 years of age; ot

263 Patients with hepatic hemangiomas that were 1 cm or larger as seen on cross-se

264 s a wide variety of human diseases,including hemangiomas, the most common tumor of childhood.

265 mature human placental vessels and infantile hemangiomas, the most common tumor of infancy and ECs.

266 apitulated the unique evolution of infantile hemangioma--the formation of blood vessels followed by i

267 be clinically and radiologically typical for hemangiomas, their HEM/liv ratios were at least 1.6 (sma

268 ropranolol exerts its suppressive effects on hemangiomas through the HIF-1alpha-VEGF-A angiogenesis a

269 in hemangioma endothelial cells (hemECs) and hemangioma tissue is markedly reduced compared to contro

270 isolation of multipotential stem cells from hemangioma tissue that give rise to hemangioma-like lesi

271 of vessels from proliferating and involuting hemangiomas to identify differentially expressed genes.

272 the current standard therapy for problematic hemangioma, to block hemangioma formation in vivo.

273 these or similar agents may be effective in hemangioma treatment.

274 shown a promising new therapy for infantile hemangioma using nonselective beta-blockers, including o

275 T homozygosity was associated with vertebral hemangiomas, varicose veins, lower blood pressures, and

276 By OCTA, the hemangioma was clearly visualized as a uniform large-cal

277 By anterior segment OCT, the racemose hemangioma was partially visualized in all cases.

278 cidental diagnosis of a pedunculated hepatic hemangioma was strongly suggested by the typical imaging

279 an increased frequency and severity of liver hemangiomas was seen in Tsc1+/- males treated with estro

280 In a subset of individuals with hemangioma, we found missense mutations in the genes enc

281 Using an experimental mouse model of human hemangioma, we found that the endothelial neoplasms deri

282 of 4 patients with unilateral iris racemose hemangioma were included in the study.

283 ents diagnosed with unilateral iris racemose hemangioma were included in the study.

284 Fourteen of 22 hemangiomas were assigned an SCS of less than 50%, and 2

285 Hemangiomas were avoided and only normal, pericyte-cover

286 e to normal placental vessels, proliferating hemangiomas were characterized by increased expression o

287 Involuting hemangiomas were characterized by the expression of chro

288 A total of 163 hemangiomas were identified in 123 patients.

289 referentially expressed in both placenta and hemangiomas were identified, including 17-beta hydroxyst

290 Results: A total of 184 hemangiomas were included.

291 ging closer an understanding of the cause of hemangioma, which will provide opportunities for the dev

292 architecture of slow-growing Ang2-expressing hemangiomas, while Ang2+/- cells were greatly impaired i

293 indicates the rare association of congenital hemangioma with hematologic abnormalities and verifies s

294 cular haemangioma or an intermediate type of hemangioma with intra- and extraarticular components.

295 omatic exudative retinal papillary capillary hemangioma with or without association with von Hippel-L

296 Superficial hemangiomas with a cobblestone appearance or rough surfa

297 Hemangiomas with a step or abrupt border of the superfic

298 Using multivariate analysis, combined hemangiomas with a superficial component and a step bord

299 the chickens developed myeloid leukosis and hemangiomas within 2 months after hatching.

300 All eyes had sectoral iris racemose hemangioma without associated iris or ciliary body solid