ライフサイエンスコーパス: hematogenous

1 agalactiae (34%), and 52% of all cases were hematogenous.

2 tes of dissemination including lymphatic and hematogenous.

3 n blood and lymphatic vessels indicated both hematogenous and lymphatic dissemination.

4 ate systemically via infected macrophages by hematogenous and lymphatic routes.

5 primary sites, to their transit through the hematogenous and/or lymphatic systems, and ending with t

6 Subacute, hematogenous, and extrapulmonary disease tends to be mor

7 ecting survival in a murine genetic model of hematogenous C. albicans infection.

8 To test whether hematogenous C. muridarum can spread to and establish a

9 esistant adhesive interactions essential for hematogenous cancer dissemination.

10 lay an important role during early stages of hematogenous cancer metastasis.

11 hought to mediate sialyl Lewis A/X-dependent hematogenous cancer metastasis.

12 (AmB) were investigated in a rabbit model of hematogenous Candida albicans meningoencephalitis.

13 Hematogenous Candida meningoencephalitis (HCME) is a rel

14 tly tested for virulence in a mouse model of hematogenous candidiasis.

15 shock with multiple organ injury early after hematogenous candidiasis.

16 -mer peptide, designated I-peptide, inhibits hematogenous carbohydrate-dependent cancer cell coloniza

17 Hematogenous CCA metastases commonly occur at distant or

18 Newly infiltrating, hematogenous CD16(+) monocytes were detected in a periva

19 ated as mediators of apoptosis, primarily in hematogenous cell systems, but their role in neuronal ap

20 those of mice lacking CD36 both in brain and hematogenous cells (CD36(-/-) -->CD36(-/-); - 72%).

21 ansgenic mice as donors, the distribution of hematogenous cells after bone marrow transplantation was

22 s suggest that a significant number of donor hematogenous cells are able to infiltrate into the brain

23 microglia and endothelial cells), and not in hematogenous cells is involved in the damage.

24 evade complement-mediated clearance from the hematogenous circulation is a novel virulence attribute

25 cated infection (n=104), and bacteremia with hematogenous complications (n=157).

26 in clonal complex (CC) 30 is associated with hematogenous complications and (2) test the hypothesis t

27 l virulence factors may increase the risk of hematogenous complications during methicillin-resistant

28 ions (V-MICs) and MRSA clone type on risk of hematogenous complications from MRSA BSI during implemen

29 ignificant trend toward increasing levels of hematogenous complications.

30 ted a significant trend toward more frequent hematogenous complications.

31 RB6-8C5 were more resistant to experimental hematogenous disseminated candidiasis if they received M

32 antibody (MAb) B6.1 increases resistance to hematogenous disseminated candidiasis in normal and SCID

33 ative urine cultures in patients at risk for hematogenous disseminated candidiasis is controversial.

34 isms of bone infection followed a pattern of hematogenous dissemination (67%), direct inoculation (25

35 transgenic expression of LMO1 also promoted hematogenous dissemination and distant metastasis, which

36 Inoculation resulted in hematogenous dissemination and logarithmic growth within

37 It develops after hematogenous dissemination and subsequent invasion of th

38 M33 does not have a role in cell-associated hematogenous dissemination but is required for viral amp

39 protein sigma1s is a critical determinant of hematogenous dissemination by type 1 reoviruses, which r

40 more, association of specific genotypes with hematogenous dissemination early in the disease course h

41 Less commonly, skin lesions may arise from hematogenous dissemination in compromised hosts with inv

42 There was a small but significant effect on hematogenous dissemination in favor of the CRT group (35

43 types that pose the greatest risk of causing hematogenous dissemination in humans.

44 ificant association between the frequency of hematogenous dissemination in Lyme disease patients and

45 hat apoptosis, which occurs at 24-48 h after hematogenous dissemination in the lungs is an important

46 es, and endothelial cells may regulate their hematogenous dissemination in the microvasculature.

47 Hematogenous dissemination is important for infection by

48 .045), providing clinical corroboration that hematogenous dissemination is related to the genetic sub

49 Hematogenous dissemination is thought to be a late event

50 limits the intravegetation proliferation and hematogenous dissemination of a tPMPs strain in experime

51 the investigation of factors involved in the hematogenous dissemination of B. burgdorferi.

52 Hematogenous dissemination of bacteria was observed micr

53 oor outcome of cancer patients occurs during hematogenous dissemination of cancer cells.

54 r cell aggregates that may contribute to the hematogenous dissemination of cancer.

55 Adhesion interactions during hematogenous dissemination of Candida albicans likely in

56 Since hematogenous dissemination of circulating tumor cells is

57 al protein 1 (tPMP-1) on the progression and hematogenous dissemination of experimental endocarditis

58 Hematogenous dissemination of HCMV via infected monocyte

59 cytes are proposed to play a key role in the hematogenous dissemination of human cytomegalovirus (HCM

60 eral blood monocytes are responsible for the hematogenous dissemination of human cytomegalovirus (HCM

61 Monocytes play a key role in the hematogenous dissemination of human cytomegalovirus (HCM

62 meningoencephalitis develops as a result of hematogenous dissemination of inhaled Cryptococcus neofo

63 Hematogenous dissemination of melanoma is a life-threate

64 ng the central nervous system, and inhibited hematogenous dissemination of primary lymphoma cells.

65 into potential adhesive mechanisms promoting hematogenous dissemination of prostate tumor cells into

66 tion and are a key cell type responsible for hematogenous dissemination of the virus.

67 ction and are proposed to be responsible for hematogenous dissemination of the virus.

68 ction and are proposed to be responsible for hematogenous dissemination of the virus.

69 >90% of cancer-related deaths, is enabled by hematogenous dissemination of tumor cells via the circul

70 and fibrin(ogen) play critical roles in the hematogenous dissemination of tumor cells, including col

71 ment of metastasis function, the hallmark of hematogenous dissemination of tumor cells.

72 Endothelial adhesion is necessary for the hematogenous dissemination of tumor cells.

73 These data support the view of hematogenous dissemination of ZIKV and implicate AXL as

74 halmitis is a serious infection secondary to hematogenous dissemination or direct inoculation of the

75 By comparison, protection against hematogenous dissemination required the induction of IL-

76 verity, and MRSA density in skin, as well as hematogenous dissemination to kidney.

77 Inhibition of IL-17A but not IL-22 led to hematogenous dissemination to kidneys, which correlated

78 Bacteremia with hematogenous dissemination was first detected 2 days aft

79 Instead, sigma1s mediates hematogenous dissemination within the infected host, whi

80 i sensu stricto may affect the occurrence of hematogenous dissemination, 104 untreated adults with er

81 also lead to gastrointestinal involvement by hematogenous dissemination, resulting in complications a

82 llular changes that allow for HCMV entry and hematogenous dissemination.

83 e aberrant biological activity that promotes hematogenous dissemination.

84 st factors, may be important determinants of hematogenous dissemination.

85 ansiently adherent leukocytes and subsequent hematogenous dissemination.

86 Tumors require a blood supply for growth and hematogenous dissemination.

87 ough the gastrointestinal tract, followed by hematogenous dissemination.

88 ion using a rabbit model of endocarditis and hematogenous dissemination.

89 amined with an in vivo model of experimental hematogenous E. coli K1 meningitis and an in vitro model

90 l nervous system in the newborn rat model of hematogenous E. coli meningitis than the parent strain.

91 inal fluid of newborn rats with experimental hematogenous E. coli meningitis, suggesting that the Glc

92 one-related plasmacytomas than in those with hematogenous EMM.

93 t role in the replication of B. anthracis in hematogenous environments.

94 Hematogenous hepatic metastases developed in 38 of 244 p

95 ce of LPS receptor (TLR4) is not required on hematogenous immune cells but is required on cells that

96 c gradient that guides the transmigration of hematogenous immune cells into the injured nerve.

97 Hematogenous immune cells may migrate to/infiltrate the

98 cedure resulted in a marked propensity for a hematogenous implant-related infection comprised of sept

99 inhibited biofilm formation in vitro and the hematogenous implant-related infection in vivo.

100 Hematogenous implant-related infections following bacter

101 be therapeutically targeted against Saureus hematogenous implant-related infections.

102 more resistant than control mice to a lethal hematogenous infection by C. albicans, as evidenced by e

103 Herein, we developed a model of hematogenous infection in which an orthopedic titanium i

104 iver and lung dysfunction were studied after hematogenous infection of Sprague-Dawley rats with 10(9)

105 e prototypic wild-type CDV(R252) showed that hematogenous infection of the choroid plexus is not a si

106 ts (n = 43) were perfused over 180 min after hematogenous infection with 10(9) live Escherichia coli

107 Coinciding with hematogenous infection, most patients had >/=2 infected

108 res of Candida albicans in a rabbit model of hematogenous infection.

109 ment and invade the tissue parenchyma during hematogenous infection.

110 les in host defense against cutaneous versus hematogenous infection.

111 Among patients with hematogenous infections, odds of endogenous endophthalmi

112 Among inpatients with hematogenous infections, the overall incidence rate of p

113 developing endophthalmitis in patients with hematogenous infections.

114 ine system may be of particular interest for hematogenous leukocyte infiltration of the central nervo

115 Hematogenous leukocytes infiltrate the CNS after inflamm

116 ) from perihepatic peritoneal metastasis and hematogenous liver metastases.

117 is virus-induced demyelination, depletion of hematogenous macrophages abrogates the demyelinating pro

118 The lysozyme M EGFP-knockin mouse tags hematogenous macrophages, but not microglia.

119 cularity and perhaps cancer dissemination by hematogenous means.

120 the blood-brain barrier in the experimental hematogenous meningitis animal model.

121 cal isolate HI689 in the infant rat model of hematogenous meningitis, an established model of invasiv

122 In a murine model of hematogenous meningitis, mice infected with beta-h/c mut

123 e the blood-brain barrier using our model of hematogenous meningitis.

124 BB in the neonatal rat model of experimental hematogenous meningitis.

125 both in vitro and in a newborn rat model of hematogenous meningitis.

126 ent strain in newborn rats with experimental hematogenous meningitis.

127 smolarity) in newborn rats with experimental hematogenous meningitis.

128 Conclusion Differentiating hematogenous metastases and LPI is important for radiolo

129 tases and LPI is important for radiologists; hematogenous metastases are associated with shorter surv

130 Hematogenous metastases are rarely present at diagnosis

131 are not highly vascularised tumours, making hematogenous metastases uncommon.

132 Hematogenous metastases were associated with significant

133 iations and prognostic importance of LPI and hematogenous metastases were studied by using univariate

134 16; 95% CI: 1.94, 4.56) were associated with hematogenous metastases.

135 ls (CTCs) represent a surrogate biomarker of hematogenous metastases.

136 ted in reduced tumor vasculature and limited hematogenous metastases.

137 Hematogenous metastasis (blood tumor burden, lung metast

138 c evidence that platelets play a key role in hematogenous metastasis and contribute to this process b

139 Our results highlight hematogenous metastasis as an important mode of ovarian

140 in samples from the 4 patients who developed hematogenous metastasis but in none of tumors from patie

141 have been able to observe the steps in early hematogenous metastasis by epifluorescence microscopy of

142 Thus, MMP-9 expression is required for hematogenous metastasis in a murine prostate model syste

143 ome 3 that reduced relative tumor growth and hematogenous metastasis in the SS.BN3(IL2Rgamma) consomi

144 red as a predictor and therapeutic target of hematogenous metastasis in TNBC patients.

145 A hematogenous metastasis mouse model revealed that PPM1A

146 fficking in both acute and chronic settings, hematogenous metastasis of carcinoma cells, effector mec

147 abiosis model that demonstrates preferential hematogenous metastasis of ovarian cancer to the omentum

148 r cells to the vascular endothelium and that hematogenous metastasis originates from the proliferatio

149 Using a mouse model of hematogenous metastasis to the lung, we observed decreas

150 A higher AR expression increases ccRCC hematogenous metastasis yet decreases ccRCC lymphatic me

151 umor cells in distant organs is required for hematogenous metastasis, but the tumor cell surface mole

152 ere in a model for TF-dependent experimental hematogenous metastasis, that TF supports metastasis by

153 use the lungs are the most common target for hematogenous metastasis, this research offers a plausibl

154 f the main host responses to coagulation for hematogenous metastasis, we examined lung metastases aft

155 f how platelets contribute to the process of hematogenous metastasis.

156 evealed that TM is a powerful determinant of hematogenous metastasis.

157 within the microvasculature and facilitates hematogenous metastasis.

158 through it occurs at least as frequently as hematogenous metastasis.

159 servation of how macrophages are involved in hematogenous metastasis.

160 The liver is a common site of hematogenous metastasis.

161 ed fibrinolysis had no significant impact on hematogenous metastasis.

162 s may contribute to the role of platelets in hematogenous metastasis.

163 ons, except for the one SM that succumbed to hematogenous metastasis.

164 nd histopathological parameters with risk of hematogenous metastasis.

165 ood vessels, thereby promoting lymphatic and hematogenous metastasis.

166 uman soft tissue sarcomas have a distinctive hematogenous metastatic pattern (predominantly lung), an

167 y demyelinating stages comprised CCR1+/CCR5+ hematogenous monocytes and CCR1-/CCR5- resident microgli

168 ) axis is a dominant pathway responsible for hematogenous omental metastasis.

169 vo tumors that develop in transplanted donor hematogenous or lymphoid cells after transplantation.

170 inal tract and disseminates systemically via hematogenous or neural routes.

171 graphy in pediatric cases of suspected acute hematogenous osteomyelitis (AHO) with nondiagnostic radi

172 In children, hematogenous osteomyelitis is an infection that primaril

173 n summary, our mouse model of staphylococcal hematogenous osteomyelitis precisely reproduces most fea

174 thritis/pyomyositis, nontraumatic meningitis/hematogenous osteomyelitis, and pneumonia) each had a si

175 and in distinguishing it from unifocal acute hematogenous osteomyelitis.

176 ue to limited virus delivery to the brain by hematogenous pathways.

177 al models: efficacy in Staphylococcus aureus hematogenous pneumonia and inhalation anthrax but no act

178 study to investigate the importation of the hematogenous precursors of thymic DCs.

179 at labels CD14 antigen present on monocytes, hematogenous precursors of tissue macrophages, did not l

180 Hematogenous precursors repopulate the thymus of normal

181 was radiosensitive and rapidly replaced from hematogenous precursors, whereas the other was relativel

182 each of these key hemostatic factors on the hematogenous pulmonary metastasis of 2 established murin

183 hat was attenuated for virulence in a murine hematogenous pyelonephritis infection model.

184 y (IM) metastasis is generally attributed to hematogenous rather than lymphatic spread.

185 jor route of drug delivery in this system is hematogenous rather than transscleral.

186 f CCR2(+) MOs/MPs rather than blocking their hematogenous recruitment.

187 r invasion of placental trophoblasts and the hematogenous release of placental debris.

188 rains induced equivalent rates and extent of hematogenous renal infection, only the tPMP(r) strain di

189 Our data also underscore that the hematogenous route might play a pivotal role in viral di

190 t manner, suggesting that fusobacteria use a hematogenous route to reach colon adenocarcinomas.

191 ination from and/or toward the brain via the hematogenous route was provided, confirming a hypothesis

192 We report that IPCs can enter PLNs via a hematogenous route, which involves a multistep adhesive

193 disseminated lymphatically rather than by a hematogenous route.

194 cells to metastasize via either lymphatic or hematogenous routes.

195 e 1 Lang (T1L), which disseminates solely by hematogenous routes.

196 E), a severe intraocular infection caused by hematogenous seeding of mycotic organisms to the eye.

197 rally injected alphaviruses enter the CNS by hematogenous seeding of the CVOs followed by centripetal

198 ater time points after infection, cells from hematogenous sources helped to partially replenish the p

199 ltapvl, and LACDeltahla D14 survivors had no hematogenous spread (P < .001).

200 d 72% of LACDeltahla-infected rabbits had no hematogenous spread and similar lung and bone bacterial

201 Our data demonstrate direct hematogenous spread as a dissemination route that contri

202 Two prominent possibilities include hematogenous spread by leukocytes and neural spread by a

203 Hematogenous spread can occur to many sites, but spleen,

204 and 85A to reduce lung pathology and prevent hematogenous spread in guinea pigs challenged with a low

205 and vascular endothelium may regulate their hematogenous spread in the microvasculature.

206 required for S. aureus fitness in vivo in a hematogenous spread infection model and a nasal colonisa

207 luble plasma FN and, thus, can happen during hematogenous spread of cancer cells at high plasma FN co

208 Modeling the hematogenous spread of cancer cells to distant organs po

209 expressed on tumor cells contributes to the hematogenous spread of colon carcinoma.

210 did not protect challenged guinea pigs from hematogenous spread of organisms to the spleen.

211 The molecular mechanisms underlying the hematogenous spread of PCs outside the bone marrow are o

212 C57BL/6 mice early during infection reduced hematogenous spread of the bacilli, suggesting that MMPs

213 irus (HCMV) pathogenesis is dependent on the hematogenous spread of the virus to host tissue.

214 The presence of SV40 in PBMCs suggests that hematogenous spread of viral infection may occur.

215 ection of vascular endothelial cells and the hematogenous spread of virus-infected leukocytes from me

216 Protecting the fetus from the hematogenous spread of viruses requires multifaceted lay

217 A propensity for hematogenous spread with resulting contamination of auto

218 ection through transscleral diffusion, local hematogenous spread, and possibly movement through the u

219 yoepithelial differentiation, proclivity for hematogenous spread, and slow but progressive clinical c

220 ichia coli meningitis develop as a result of hematogenous spread, but it is not clear how circulating

221 Outcomes (mortality, hematogenous spread, lung and bone involvements) of rabb

222 llary beds (such as within the brain) during hematogenous spread, thereby facilitating blood-to-brain

223 To decipher the mechanism of hematogenous spread, we focused on the viral dysregulati

224 aperitoneal inoculation were consistent with hematogenous spread.

225 illimeters and cells lack routes for distant hematogenous spread.

226 rst immune competent mouse model for distant hematogenous spread.

227 o be required for early lung involvement via hematogenous spread.

228 ized by a propensity for early lymphatic and hematogenous spread.

229 olves lymphatic dissemination in addition to hematogenous spreading.

230 at IRS4 is not significantly involved in the hematogenous stage of disease.

231 ut how ILC2s egress from the bone marrow for hematogenous trafficking.

232 ysical and immunological barrier against the hematogenous transmission of viruses from mother to fetu

233 can originate from the oral cavity following hematogenous transmission.

234 ing from the lower reproductive tract or via hematogenous transmission.

235 nocrotaline pyrrole in the liver followed by hematogenous transport to the lung where it injures pulm

236 mic domain to support the complex process of hematogenous tumor cell dissemination.

237 Tissue factor also supports hematogenous tumor dissemination.

238 ghlights how this interaction is involved in hematogenous tumor metastasis.

239 ns of thrombospondin-1, which is involved in hematogenous tumor spread, invasion and angiogenesis, an

240 inical trials for the treatment of solid and hematogenous tumors.

241 The role of hematogenous vasculature and development of angiogenic b

242 ti-step carcinogenesis and in the control of hematogenous versus lymphatic metastasis are unknown.

243 promote subsequent infection of T cells and hematogenous virus spread.

244 Fifty-two were hematogenous, with poorer prognoses, and 88% were caused