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1 t least 10(1)(3)-fold) expansion of immature hematopoietic progenitors.
2 ecreased expression of multiple Hox genes in hematopoietic progenitors.
3 and disrupts cis-regulatory architecture of hematopoietic progenitors.
4 s proliferation of embryonic fibroblasts and hematopoietic progenitors.
5 erate with GATA1s in transformation of fetal hematopoietic progenitors.
6 e expression of ETO and RUNX1 genes in human hematopoietic progenitors.
7 ythroid-specific genes within populations of hematopoietic progenitors.
8 tem cells (HSCs) and other lineage-committed hematopoietic progenitors.
9 the in vitro differentiation of iPSC toward hematopoietic progenitors.
10 udied erythropoiesis using knockout mice and hematopoietic progenitors.
11 lineages and colony-forming unit assays for hematopoietic progenitors.
12 y in the absence of PRC1, to fully transform hematopoietic progenitors.
13 nervous system (SNS) regulates neuronal and hematopoietic progenitors.
14 alternative for studying telomere crisis in hematopoietic progenitors.
15 ty of mast cells to differentiate from their hematopoietic progenitors.
16 odor environments fail to sustain a pool of hematopoietic progenitors.
17 ) and mouse bone marrow cells, which contain hematopoietic progenitors.
18 ile promoting the self-renewal of very early hematopoietic progenitors.
19 definitive repopulation status on primitive hematopoietic progenitors.
20 ent apoptotic effectors targeting autologous hematopoietic progenitors.
21 olonies, indicating that these cells are not hematopoietic progenitors.
22 HES1) expression and generation of committed hematopoietic progenitors.
23 eukemogenic in vivo when expressed in normal hematopoietic progenitors.
24 induction of myeloid fate from hESC-derived hematopoietic progenitors.
25 factor (SCF) is expressed on mast cells and hematopoietic progenitors.
26 ytokine signaling to HSCs and more committed hematopoietic progenitors.
27 nome to direct fate lineage determination of hematopoietic progenitors.
28 ommitment were mediated by beta3 integrin on hematopoietic progenitors.
29 hat regulate the differentiation capacity of hematopoietic progenitors.
30 osine kinase that leads to transformation of hematopoietic progenitors.
31 evelop from MPP2, a myeloid-biased subset of hematopoietic progenitors.
32 filtration of the bone marrow by transformed hematopoietic progenitors.
33 e enriched in NKT progenitors, like in other hematopoietic progenitors.
34 es the ex vivo characterization of zebrafish hematopoietic progenitors.
35 HPs transcriptionally resemble native Kit(+) hematopoietic progenitors.
36 oform of SON enhances replating potential of hematopoietic progenitors.
37 also revealed a prethymic role for BCL11B in hematopoietic progenitors.
38 -BP1) and 4E-BP2 as compared with most other hematopoietic progenitors.
39 promote monocyte/macrophage development from hematopoietic progenitors, a process critical in trigger
40 spheres can significantly expand multipotent hematopoietic progenitors able to engraft immunodeficien
41 B cells into IFrag(-/-) mice protects early hematopoietic progenitor activity during systemic respon
42 mice resulted in an accelerated recovery of hematopoietic progenitor activity in bone marrow and a m
43 iver exhibited severe deficiency in HSCs and hematopoietic progenitors, along with elevated reactive
44 iota is known to influence the generation of hematopoietic progenitors, although the pathways underly
45 esized that the arterial wall is a source of hematopoietic progenitor and stem cells in postnatal lif
46 scontinuous sinusoids also allow circulating hematopoietic progenitor and stem cells to populate the
47 potent stem (iPS) cell reprogramming of aged hematopoietic progenitors and allowed the resulting aged
49 hat express a hyperactive mutant of Stat5 in hematopoietic progenitors and derived lineages in a liga
50 rophages are derived from primitive yolk-sac hematopoietic progenitors and exhibit hallmarks of M2 ac
51 ia (MLL) trigger aberrant gene expression in hematopoietic progenitors and give rise to an aggressive
53 L-RARA mice, which express PML-RARA in early hematopoietic progenitors and myeloid precursors, with o
54 tablished that during embryonic development, hematopoietic progenitors and stem cells are generated f
56 vites evolutionary parallels with vertebrate hematopoietic progenitors and the independent myeloid sy
57 nt by preserving immune resources, including hematopoietic progenitors and thymic activity, which cou
58 protein synthesis in HSCs, but not in other hematopoietic progenitors, and impaired their reconstitu
59 matopoietic engraftment and clonogenicity of hematopoietic progenitors, and is dependent on secreted
60 ression, enhanced self-renewal, expansion of hematopoietic progenitors, and myeloid differentiation b
61 deletion of Chd1 leads to loss of definitive hematopoietic progenitors, anemia, and lethality by embr
64 ence with expansion and differentiation into hematopoietic progenitors are incompletely understood.
68 oughout adult life, macrophages derived from hematopoietic progenitors are seeded throughout the body
69 tability; and (3) increasing self-renewal in hematopoietic progenitors, as all of these events are af
70 plerixafor results in rapid mobilization of hematopoietic progenitors, but fails to mobilize 33% of
71 iple subsets of highly purified intermediate hematopoietic progenitors by wild-type HIV both in vitro
73 by which that occurs, using an immortalized hematopoietic progenitor cell line, EML-C1, as a model s
74 igratory responses of cocultured stromal and hematopoietic progenitor cell lines, helping explain how
75 factor (VEGF), VEGF receptor, and CD34/CD31 (hematopoietic progenitor cell marker/endothelial cell ma
76 ability in hematopoietic stem cell (HSC) and hematopoietic progenitor cell populations from young and
77 Somatic mutations were tracked to CD34(+) hematopoietic progenitor cell populations, being further
78 ation of ERK in these cells led to rescue of hematopoietic progenitor cell proliferation in vitro and
79 ug sensitivity, and abrogated MPP1-dependent hematopoietic progenitor cell replating in methylcellulo
80 s of thrombotic microangiopathy secondary to hematopoietic progenitor cell transplantation, infection
81 ith significantly increased numbers of HSCs, hematopoietic progenitor cell-1 (HPC-1), HPC-2, and Lin(
84 report that inhibition of Notch signaling in hematopoietic progenitor cells (HPC), myeloid-derived su
85 xpression of RUNX1a facilitates emergence of hematopoietic progenitor cells (HPCs) and positively reg
87 oiesis characterized by increased numbers of hematopoietic progenitor cells (HPCs) at the expense of
88 hierarchy among intermediate populations of hematopoietic progenitor cells (HPCs) derived from human
89 fety and effectiveness of mobilizing CD34(+) hematopoietic progenitor cells (HPCs) in adults with bet
92 d CD34(+)CXCR4(+) cells as well as assayable hematopoietic progenitor cells (HPCs) irrespective of th
93 rus (HCMV) can establish latent infection in hematopoietic progenitor cells (HPCs) or CD14 (+) monocy
94 (HSCs), impaired radioprotective function of hematopoietic progenitor cells (HPCs), and myeloid and e
95 determine the effect of fibrosis on healthy hematopoietic progenitor cells (HPCs), bioartificial mat
96 t5 deletion resulted in a concurrent loss of hematopoietic progenitor cells (HPCs), leading to fatal
97 d lung homing of bone marrow-derived CD34(+) hematopoietic progenitor cells (HPCs), which include eos
98 c stem cells (HSCs) generate highly dividing hematopoietic progenitor cells (HPCs), which produce all
106 production of large numbers of primary human hematopoietic progenitor cells (HPs) capable of differen
107 transcriptomic profiling of normal human HSC/hematopoietic progenitor cells [HPCs], revealing that se
108 ed for LC differentiation from human CD34(+) hematopoietic progenitor cells and blood monocytes in vi
109 iferation and appropriate differentiation of hematopoietic progenitor cells and in animal hematopoies
110 tein that confers self-renewal capability to hematopoietic progenitor cells and induces acute myeloge
111 ga-dose" of T cell-depleted peripheral blood hematopoietic progenitor cells and no posttransplant pha
112 patient can be induced to differentiate into hematopoietic progenitor cells and then further to eryth
113 ired for latency and reactivation in CD34(+) hematopoietic progenitor cells and virion maturation in
114 The findings indicate that Th2-promoting hematopoietic progenitor cells are rapidly recruited to
116 wth factor A (Vegf-a)-dependent apoptosis of hematopoietic progenitor cells associated with overprodu
117 opoiesis and changes in pre-mRNA splicing in hematopoietic progenitor cells by whole transcriptome an
119 Recent studies have found that peripheral hematopoietic progenitor cells contribute to type 2 cyto
120 fies frequencies of growth-factor responsive hematopoietic progenitor cells during steady state and a
121 n attenuated strain of CMV are maintained in hematopoietic progenitor cells during their differentiat
122 reviously shown that HCMV infection of human hematopoietic progenitor cells engrafted in immune defic
124 tropenias and for mobilization of peripheral hematopoietic progenitor cells for stem cell transplanta
125 ultured from peripheral blood or bone marrow hematopoietic progenitor cells from four patients were u
126 ce-activated cell sorting (FACS) of c-kit(+) hematopoietic progenitor cells from mixed bone marrow po
127 BM) chimeras were generated by transplanting hematopoietic progenitor cells from stress-susceptible m
128 creased rDNA promoter methylation in CD34(+) hematopoietic progenitor cells from the majority of MDS
130 creased the proportion of JAK2V617F-positive hematopoietic progenitor cells in 6 PV patients studied.
131 e proportion of phenotypic HSCs and immature hematopoietic progenitor cells in phase G0 of the cell c
132 tly used to stimulate bone marrow release of hematopoietic progenitor cells in preparation for stem c
133 hich a low ROS level is required to maintain hematopoietic progenitor cells in the tissue and to redu
134 for E-selectin binding and for migration of hematopoietic progenitor cells into the bone marrow.
135 CCR9 controls the immigration of multipotent hematopoietic progenitor cells into the thymus to sustai
136 skewing promote oncogenic transformation of hematopoietic progenitor cells into therapy-resistant le
140 lation and the expression of PML-RARalpha in hematopoietic progenitor cells prevented differentiation
141 ients with systemic histiocytoses resides in hematopoietic progenitor cells prior to committed monocy
143 elogenous leukemia (CML) caused normal mouse hematopoietic progenitor cells to divide more readily, a
146 y glycosyltransferases, and decorates marrow hematopoietic progenitor cells with alpha2,6-linked sial
147 f a human cell AML, generated in CD34+ human hematopoietic progenitor cells xenografted into immunoco
148 thma, decreased B-lymphocyte development and hematopoietic progenitor cells, and lymphoid organ hypop
149 ndogenously expressed by a mast cell line or hematopoietic progenitor cells, and specifically blocks
150 n, intermediate reactivity toward monocytes, hematopoietic progenitor cells, and T-cells was observed
151 is detected in hematopoietic stem cells and hematopoietic progenitor cells, and that its expression
152 combined with Peg IFN-alpha 2a can target PV hematopoietic progenitor cells, eliminating the numbers
153 cells, we transduced lineage-depleted murine hematopoietic progenitor cells, observing GFP expression
154 asia, fibrosis, and impaired colonization by hematopoietic progenitor cells, resulting in anemia and
155 of T-lineage specification in human CD34(+) hematopoietic progenitor cells, similar to ICN1 overexpr
157 Although both ligands activated Notch in hematopoietic progenitor cells, they had an opposite eff
158 t-like or a replicative infection in CD34(+) hematopoietic progenitor cells, we defined classes of lo
159 ssion and ex vivo differentiation of CD34(+) hematopoietic progenitor cells, we demonstrate that C/EB
184 eukemia (AML) represents a clonal disease of hematopoietic progenitors characterized by acquired hete
185 this study, we test the assumption that the hematopoietic progenitor/colony-forming cells of the emb
187 ECs generated substantially more CD34+CD45+ hematopoietic progenitors compared with cells cocultured
189 find that deletion of Cebpa rendered murine hematopoietic progenitors completely resistant to MLL-EN
191 and KD of miR-486-5p in primary fetal liver hematopoietic progenitors demonstrated that miR-486-5p c
194 L cells, as CHD4 depletion in normal CD34(+) hematopoietic progenitors does not increase their suscep
195 nsgene or by homozygous knock-out of Phd2 in hematopoietic progenitors driven by a Vav1-Cre transgene
198 kg/day activated telomerase 2-4 fold both in hematopoietic progenitors ex vivo and in bone marrow and
199 wed the visualization and differentiation of hematopoietic progenitors ex vivo in real-time with time
200 the c-Kit receptor tyrosine kinase to elicit hematopoietic progenitor expansion but can be toxic when
204 Pgamma are not restricted to fibroblasts, as hematopoietic progenitors from Cebpg(-/-) bone marrow al
205 imeric mice (Cdk5(+/+C) or Cdk5(-/-C)) using hematopoietic progenitors from either embryonic day 16.5
207 reviously demonstrated that the induction of hematopoietic progenitors from fibroblasts progresses th
208 gulation of SLPI in CD34(+) bone marrow (BM) hematopoietic progenitors from healthy individuals resul
209 omide-induced reprogramming was conserved in hematopoietic progenitors from individuals with sickle c
210 supporting B lymphopoiesis in vitro, whereas hematopoietic progenitors from mutant mice exhibit norma
211 ha-dependent inhibitory effects on malignant hematopoietic progenitors from patients with chronic mye
212 Ns to exert suppressive effects in malignant hematopoietic progenitors from patients with polycythemi
215 ng hematopoietic cells and bone marrow-based hematopoietic progenitors, functional evidence of the ce
217 found Cdc73 promotes expression of an early hematopoietic progenitor gene program that prevents diff
219 reases proliferation of these most primitive hematopoietic progenitors, giving rise to higher levels
220 edullary zone which contain undifferentiated hematopoietic progenitors has many, closely spaced membr
221 nclear, and direct infection of intermediate hematopoietic progenitors has not been established as a
223 ufficiency underlies the clonal expansion of hematopoietic progenitors in a large fraction of human m
225 us to explore the effects of antibiotics on hematopoietic progenitors in detail using a murine model
226 Despite markedly reduced cellularity of hematopoietic progenitors in E18.5 bone marrow, the numb
227 st mature granulocytes, but not toward human hematopoietic progenitors in humanized immune reconstitu
228 irculation prevented CBLB502 from protecting hematopoietic progenitors in lethally irradiated mice, i
229 ated proliferation of adoptively transferred hematopoietic progenitors in the bone marrow of mice wit
230 without adversely affecting human clonogenic hematopoietic progenitors in vitro, or murine hematopoie
234 treatment with TNF-alpha of lineage-negative hematopoietic progenitors increased NK and myeloid diffe
235 n murine models, forced expression of MN1 in hematopoietic progenitors induces an aggressive myeloid
236 oid leukemia, mutated cells transform normal hematopoietic progenitors into "leukemic like" cells thr
237 olute a mixture of ES cells, fibroblasts and hematopoietic progenitors into high-quality chromatin st
238 normal gene expression networks to reprogram hematopoietic progenitors into preleukemic stem cells, a
240 ed with BCR-ABL1-positive ALL, a multipotent hematopoietic progenitor is affected by the BCR-ABL1 fus
241 standing how CMV interacts with LC and their hematopoietic progenitors is thus essential to develop i
242 p1 constitutively co-immunoprecipitated with hematopoietic progenitor kinase 1 (HPK1) in neutrophil-l
243 this issue of Blood, Jakob et al report that hematopoietic progenitor kinase 1 (HPK1) participates du
244 itment of the inhibitory signaling molecules hematopoietic progenitor kinase 1 and SH2-containing ino
247 rogenitor cells expressing SMC, myeloid, and hematopoietic progenitor-like properties and that differ
248 one marrow, especially in B-cell lineage and hematopoietic progenitors; lineage tracing identified th
249 known to function as a positive regulator of hematopoietic progenitor maintenance in the lymph gland
251 at, in Drosophila, olfactory signals control hematopoietic progenitor maintenance, thus uncovering a
252 cuit that controls quiescence of MB-HSCs and hematopoietic progenitors marked by histidine decarboxyl
254 GATA1 suppression in ES and iPS cell-derived hematopoietic progenitors may enhance megakaryocyte prod
255 in the transcriptional states of developing hematopoietic progenitors may generally shape the mutati
256 proliferation and blocked differentiation of hematopoietic progenitors mediated, in part, by altered
257 sed by HSCs, and at lower levels by c-kit(+) hematopoietic progenitors, megakaryocytes, and Leptin Re
260 atopoietic stem cells (HSCs) and multipotent hematopoietic progenitors (MPPs) are routinely isolated
261 e between proliferation and growth arrest in hematopoietic progenitors, myeloid lineage specific dele
266 is SCF variant elicited biased activation of hematopoietic progenitors over mast cells in vitro and i
268 consist of G-CSF-dependent shifts of marrow hematopoietic progenitor populations including expansion
269 e, we sequenced RNA from eight primary human hematopoietic progenitor populations representing the ma
272 lymphoid cell fate is orchestrated in early hematopoietic progenitors remains poorly understood.
273 nitial activation of the Gata1 gene in early hematopoietic progenitors remains to be elucidated.
274 Ai to 20-30% of normal levels in multipotent hematopoietic progenitors resulted in clonal dominance o
275 d, consistent with a deficiency of primitive hematopoietic progenitors, serum levels of the hematopoi
276 for occluding-junctions in regulating niche-hematopoietic progenitor signalling and link this mechan
277 tor ARID3a is expressed in a subset of human hematopoietic progenitor stem cells in both healthy indi
279 Recently, ST2 expression was described on hematopoietic progenitor subsets, where its function rem
280 uced beta1- and beta2-integrin expression on hematopoietic progenitors suggests that increased spleni
282 ays an important role in the niche to expand hematopoietic progenitors through the modulation of seve
284 Hypercholesterolemia acts in platelets and hematopoietic progenitors to exacerbate thrombosis and a
285 pectedly, Cdk6 R31C impairs the potential of hematopoietic progenitors to repopulate upon adoptive tr
286 are cytokines, which regulate commitment of hematopoietic progenitors to the different blood lineage
287 (EndoMT) and the recruitment of circulating hematopoietic progenitors to the heart have been reporte
288 in vivo by creating bone marrow chimera from hematopoietic progenitors transduced with an inducible s
289 gnaling does not alter gene expression until hematopoietic progenitors transition from fetal to adult
290 howed that CARM1 is required for survival of hematopoietic progenitors under conditions that promote
291 ts lineage choice in differentiating primary hematopoietic progenitors using image patches from brigh
294 h-risk LCH arises from somatic mutation of a hematopoietic progenitor, whereas low-risk disease arise
295 ures, addition of Indian Hh ligand increased hematopoietic progenitors, whereas chemical inhibition o
296 ensing dependence through RagA and mTORC1 in hematopoietic progenitors, which dynamically drive matur
297 iated silencing of TMEM131L in human CD34(+) hematopoietic progenitors, which were then grafted in NO
299 a highly selective ligand for E-selectin on hematopoietic progenitors with unexpected important cont
300 chemical inhibition of Hh signaling reduced hematopoietic progenitors without affecting primitive st
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