ライフサイエンスコーパス: hemopoietic

1 Rbeta chain-deficient mice exhibited similar hemopoietic abnormalities.

2 ation between levels of c-myb expression and hemopoietic activity of the tissues and cells examined,

3 can be used as a novel and unique source of hemopoietic and DC precursors as well as DCs at differen

4 hat MRP14 deficiency is required in both the hemopoietic and intrinsic cells for the protective effec

5 ataset comprising pure cell populations from hemopoietic and non-hemopoietic cell types.

6 urprisingly, costimulatory molecules on both hemopoietic and nonhematopoietic cells are required for

7 ata illustrate the complex interplay between hemopoietic and nonhemopoietic cell types for the develo

8 We report that direct recognition of hemopoietic and nonhemopoietic cells are individually ra

9 Hemopoietic and nonhemopoietic cells contribute to TLR4-

10 gs suggest a model in which TLR signaling in hemopoietic and nonhemopoietic cells mediate three disti

11 To differentiate the role of A2a on hemopoietic and nonhemopoietic cells, we created chimeri

12 CD38 exerts pleiotropic actions in hemopoietic and nonhemopoietic compartments via effects

13 onstrating that immunity requires STAT6(-/-) hemopoietic and nonhemopoietic components.

14 a an IFN-gamma-dependent mechanism involving hemopoietic and nonhemopoietic derived cells, and is not

15 Further studies revealed that hemopoietic and nonhemopoietic expression of the cytokin

16 Indeed, it is not known whether hemopoietic and/or nonhemopoietic expression of TACE is

17 ernatively, hearts that lack MHC class II on hemopoietic APCs are acutely rejected at a significantly

18 Hearts that express MHC class II on hemopoietic APCs are acutely rejected in a mean of 7 day

19 ulatory capacity of endothelium from that of hemopoietic APCs by using bone marrow chimeras.

20 mportant in transplantation, because, unlike hemopoietic APCs, allogeneic vascular endothelium remain

21 Unlike graft-resident donor-derived hemopoietic APCs, which decrease in number over time aft

22 alpha as a mediator within the neural-immune-hemopoietic axis.

23 D44 is a transmembrane adhesion molecule and hemopoietic CD44 has an essential role in hyaluronan cle

24 Reconstitution of hemopoietic CD44 reversed the inflammatory phenotype.

25 ach cell type before skin grafting abolished hemopoietic cell engraftment and prevented allograft acc

26 Donor hemopoietic cell engraftment is considered to be an indi

27 Like hemopoietic cell homing, levels of stromal cell-derived

28 hemokine receptors thought to be involved in hemopoietic cell homing, stromal cell-derived factor-1 a

29 to the activation of Src Family Kinase (SFK)/hemopoietic cell kinase (Hck) and suppression of apoptos

30 n-3, activated a Src kinase family molecule, hemopoietic cell kinase (Hck), and induced cellular adhe

31 32D cells are a murine hemopoietic cell line that undergoes apoptosis upon with

32 The donor hemopoietic cell lineage(s) responsible for the inductio

33 kDa) is an adaptor molecule expressed in all hemopoietic cell lineages except mature B cells and is k

34 l ablation as well as a tool to characterize hemopoietic cell lineages.

35 d the expression of CD148 on multiple murine hemopoietic cell lineages.

36 nd in multiple adult tissues, including most hemopoietic cell lineages.

37 or the motheaten viable (me-v) allele of the hemopoietic cell phosphatase (Hcph) gene.

38 Furthermore, analysis of tumor hemopoietic cell populations showed that effective, MSU-

39 ovel role for this molecule in adhesion of a hemopoietic cell to laminin-1.

40 -versus-host disease (GVHD) after allogeneic hemopoietic cell transplantation (alloHCT).

41 alignancy, for donor selection in allogeneic hemopoietic cell transplantation, and for models of NK t

42 ject donor grafts following nonmyeloablative hemopoietic cell transplantation.

43 of morbidity and mortality after allogeneic hemopoietic cell transplantation.

44 Most clinical allogeneic hemopoietic cell transplants (alloHCT) are now performed

45 Collectively, our findings show how multiple hemopoietic cell types regulate mTEC development through

46 of the activation and/or function of various hemopoietic cell types.

47 mulatory and inhibitory roles within several hemopoietic cell types.

48 re cell populations from hemopoietic and non-hemopoietic cell types.

49 emopoietic cell types or radiation-sensitive hemopoietic cell types.

50 nhancing an anti-inflammatory loop involving hemopoietic cell-produced IL-10 acting on brain parenchy

51 To determine the contribution of the hemopoietic cell-restricted PI3K delta in neutrophil che

52 of guanine exchange factors and a prominent hemopoietic cell-specific protein tyrosine kinase substr

53 CD45 (leukocyte common) antigen is a hemopoietic cell-specific tyrosine phosphatase essential

54 the previously described first exon found in hemopoietic cells (1E(A)) and approximately 42 bp upstre

55 ers of adult liver cells (cytochrome P450s), hemopoietic cells (CD45), and mesenchymal cells (vascula

56 kinase family, is predominantly expressed in hemopoietic cells and binds specifically to the common g

57 Using [(35)S]Sch225336, we assayed hemopoietic cells and cell lines to quantitate the expre

58 e report that they originate from peripheral hemopoietic cells and exhibit diverse functions that cha

59 stamine H(4) receptor is highly expressed in hemopoietic cells and is a promising new target for the

60 Jak3 is preferentially expressed in hemopoietic cells and is up-regulated upon cell differen

61 To define the roles of FcR-bearing hemopoietic cells and of kidney resident mesangial cells

62 Chemokines regulate the migration of hemopoietic cells and play an important role in the path

63 results indicate that CpG targets recipient hemopoietic cells and that its pro-rejection effects cor

64 Wild-type chimeric mice bearing TLR4 mutant hemopoietic cells and TLR4 mutant mice transplanted with

65 ession of protective MHC class II alleles in hemopoietic cells could be used to prevent the recurrenc

66 reveal that AhR-mediated events external to hemopoietic cells direct dioxin-enhanced IFN-gamma produ

67 ogenous GCs can program endotoxin-responsive hemopoietic cells during their differentiation by regula

68 Most hemopoietic cells express one or more members of the Ly-

69 ury, revealing that PPT-A gene expression in hemopoietic cells has a previously unanticipated essenti

70 rophages mediate strong rejection of porcine hemopoietic cells in mice.

71 tween capsaicin-sensitive sensory fibers and hemopoietic cells in neurokinin-mediated inflammation an

72 In most of these studies, virtually all the hemopoietic cells in the NOD recipients eventually conve

73 significant role in the clearance of porcine hemopoietic cells in vivo.

74 since PD-L1 is expressed by parenchymal and hemopoietic cells in WT kidneys, we explored the differe

75 , as well as genes not normally expressed in hemopoietic cells including inhibitor of DNA binding 4.

76 Third, enhancement of chemotaxis of hemopoietic cells is also mediated by C3a-desArg, which

77 V is expressed by a subpopulation of CD34(+) hemopoietic cells isolated from cord blood and that thes

78 and add to the growing body of evidence that hemopoietic cells may use unique molecular intermediates

79 ply, lesion characteristics, and circulating hemopoietic cells numbers before and after successful PC

80 of the p50/p105 subunit of NF-kappaB within hemopoietic cells of the innate immune system interferes

81 strated that the presence of p50/p105 within hemopoietic cells of the innate immune system was necess

82 Thus, in vivo both radioresistant and hemopoietic cells play key nonredundant roles in mediati

83 e of Ag presentation by a majority (>99%) of hemopoietic cells surprisingly also allowed initial prim

84 ning inositol phosphatase SHIP1 functions in hemopoietic cells to limit activation events mediated by

85 we tested the ability of FL-mobilized donor hemopoietic cells to promote induction of skin graft tol

86 gated inflammation and innate immunity in FA hemopoietic cells using mice deficient in Fanconi comple

87 spleen and bone marrow, Flt3-L production by hemopoietic cells was critical for generation of normal

88 ereas LTbetaR expression by both stromal and hemopoietic cells was needed to prevent apoptosis.

89 beta-chain molecules in bone marrow-derived hemopoietic cells was resistant to induction by PD-1-PD-

90 o donor cells, presumably by destroying host hemopoietic cells without causing GvHD.

91 secretion are found in both melanocytes and hemopoietic cells, and are dysfunctional in genetic dise

92 A-2, normal cell expression is restricted to hemopoietic cells, and boosting the immune response to t

93 ur results indicate that PD-L1 expression on hemopoietic cells, and not parenchymal cells, is primari

94 WASP expression is limited to hemopoietic cells, and WASP regulates the actin cytoskel

95 demonstrate that AhR-regulated events within hemopoietic cells, but not directly within CD8+ T cells,

96 nase initially found to be expressed only in hemopoietic cells, has now been shown to be expressed in

97 DCAL-1 has restricted expression in hemopoietic cells, in particular, DCs and B cells, but T

98 athway is important for several functions in hemopoietic cells, including the suppression of apoptosi

99 cyte survival required LTalpha expression by hemopoietic cells, independent of developmental defects

100 tyrosine phosphatase expressed on nucleated hemopoietic cells, is prominently involved in T cell act

101 on requires MHC class II expression on donor hemopoietic cells, nonhemopoietic cells, or both.

102 n agreement with this finding, in 32D murine hemopoietic cells, nuclear translocation of IRS-1 correl

103 Thus, activating FcRs on circulating hemopoietic cells, rather than on mesangial cells, are r

104 ation in growth factor-dependent survival of hemopoietic cells, the role of glucose energy metabolism

105 alleled by thyroidal infiltration of CD45(+) hemopoietic cells, which increased from an average of 4%

106 ikely tick-borne and replicates primarily in hemopoietic cells, which may lead to disregulation of pr

107 uman TF involved in lineage specification of hemopoietic cells.

108 nic isoforms were detected on the surface of hemopoietic cells.

109 regulatory cytokine with diverse effects on hemopoietic cells.

110 x NZW)F1 mice expressing activating FcRs in hemopoietic cells.

111 ays both stimulatory and inhibitory roles in hemopoietic cells.

112 but also inhibits apoptosis of other normal hemopoietic cells.

113 ass II was expressed either on somatic or on hemopoietic cells.

114 he ligand for 2B4, CD48, is expressed on all hemopoietic cells.

115 amily, only c-Cbl and Cbl-b are expressed in hemopoietic cells.

116 is widely expressed in both parenchymal and hemopoietic cells.

117 c-myb may be expressed primarily in immature hemopoietic cells.

118 pha acts as a chemoattractant for immune and hemopoietic cells.

119 ssential for differentiation and function of hemopoietic cells.

120 -myb transcription was detected only in some hemopoietic cells; these cells, however, belong to sever

121 We set out to identify the specific hemopoietic cellular populations in which the AHR was ac

122 Using hemopoietic chimeras, we show that the impaired function

123 omponent, a stable state of mixed allogeneic hemopoietic chimerism sufficient to inhibit T1D developm

124 of cells of donor origin in recipients with hemopoietic chimerism.

125 tic MCMV load by 4-log(10) and promoted full hemopoietic chimerism.

126 Although allogeneic hemopoietic chimerization can clearly provide a means fo

127 n reports in which T1D-protective allogeneic hemopoietic chimerization was established in NOD mice th

128 Thus, through TNF production, the hemopoietic compartment initiates the signals for its ow

129 mixed bone marrow chimeric mice in which the hemopoietic compartment was reconstituted with a mixture

130 development involved a cis effect within the hemopoietic compartment.

131 to analyze functions of TRAF6 in vivo in the hemopoietic compartment.

132 epithelial cell (mTEC) development involves hemopoietic cross-talk, and numerous TNFR superfamily me

133 ing molecular differences in fetal and adult hemopoietic cross-talk.

134 s-like tyrosine kinase-3 ligand (Flt3L) is a hemopoietic cytokine that stimulates the production of d

135 resulting increased production of Wnt10b and hemopoietic cytokines by T cells and SCs, respectively,

136 red for ovx to increase SC production of the hemopoietic cytokines interleukin (IL)-6, IL-7, and gran

137 Thus, early hemopoietic cytokines such as FLT3-L, stem cell factor,

138 emonstrated significantly elevated levels of hemopoietic cytokines such as fms-like tyrosine kinase l

139 sing from mutations of WAS protein (WASP), a hemopoietic cytoskeletal protein.

140 Studies have implicated migratory hemopoietic DCs in this process, but direct demonstratio

141 These severe hemopoietic defects originate from a proliferative impai

142 UP-LPS induction of IL-1beta and IL-10 were hemopoietic dependent, and GM-CSF was nonhemopoietic dep

143 pathology, which in large part is driven by hemopoietic-derived cytokines such as TNF-alpha.

144 could be activated in the thymocytes but not hemopoietic-derived dendritic cells or other APCs.

145 L-7 expression is initiated independently of hemopoietic-derived signals during thymic organogenesis,

146 nase activity and are believed to deregulate hemopoietic development in a manner analogous to BCR-ABL

147 udies for PU.1 function in transcription and hemopoietic development is discussed.

148 TCR genes were expressed abnormally early in hemopoietic development, indicating that RAG-mediated re

149 and VEGFR2/KDR/Flk-1, has been documented in hemopoietic development.

150 As a first step, we induced hemopoietic differentiation by coculture of hES cells wi

151 sine kinase signaling is essential for early hemopoietic differentiation, but only marginally affects

152 so provide new insights on the mechanisms of hemopoietic dysregulation in FHL.

153 PrP(C) expression in the lymphoid, nervous, hemopoietic, endocrine, and certain epithelial tissues o

154 ich causes a very high degree of deletion in hemopoietic/endothelial progenitor cells but without del

155 The difficulty in achieving donor hemopoietic engraftment across highly disparate xenogene

156 hat the dose of irradiation influences donor hemopoietic engraftment and affects generation of anti-d

157 ulating macrophage-microbicidal activity and hemopoietic function.

158 t necessarily translate into preservation of hemopoietic function.

159 G-CSF is a hemopoietic growth factor that has a role in steady stat

160 ly express murine Flt3 ligand (FL), a potent hemopoietic growth factor that promotes the differentiat

161 ulate continued interest in the potential of hemopoietic growth factors (, thrombopoietin and interle

162 Finally, several hemopoietic growth factors were found to induce Egr gene

163 s of B6 mice, yet this resistance depends on hemopoietic IL-10 activity.

164 Interestingly, hemopoietic IL-10 was required for maintaining the resis

165 referentially expressed in a cell of a given hemopoietic lineage.

166 xpressed constitutively by cells of a single hemopoietic lineage.

167 oenvironment that impairs development in all hemopoietic lineages.

168 sels with no detectable differentiation into hemopoietic lineages.

169 oreceptor and integrin signaling in multiple hemopoietic lineages.

170 s that were not present in nonmegakaryocytic hemopoietic marrow cells from the same patient.

171 The hemopoietic microenvironment consists of a diverse reper

172 he results further reveal a new role for the hemopoietic microenvironment in B cell development in vi

173 enesis of many human malignancies, including hemopoietic neoplasms.

174 chimeric mice deleted of TLR9 in either the hemopoietic or nonhemopoietic compartments demonstrated

175 spensions of the head kidney (HKL), the main hemopoietic organ in teleosts, showed a univariate type

176 ted diabetes) in these animals, suggesting a hemopoietic origin for their IENK cell defect.

177 Professional APCs of hemopoietic-origin prime pathogen-specific naive CD8 T c

178 Deletion of either lipocalin-type or hemopoietic PGD synthase enzymes decreased urinary tetra

179 enic mice lacking leukotriene C(4) synthase, hemopoietic PGD(2) synthase, N-deacetylase/N-sulfotransf

180 n numbers of CD34/CD133-positive circulating hemopoietic precursor cells and CFI (r=0.75, P<0.001).

181 capable of resorbing bone, are derived from hemopoietic precursor cells of monocyte-macrophage linea

182 to modulate osteoclast differentiation from hemopoietic precursor cells of the monocyte-macrophage l

183 This included the loss of uncommitted hemopoietic precursor cells.

184 in normal mice, resulting in a reduction of hemopoietic precursors by 50% and of neutrophils by 43%.

185 Fetal liver (FL) hemopoietic precursors from these mice were used to gene

186 and dermal DCs), and DCs derived from CD34+ hemopoietic precursors in bone marrow, umbilical cord bl

187 ogress in the generation of DCs from defined hemopoietic precursors in vitro has revealed the heterog

188 d in receiving LT-dependent signals from the hemopoietic precursors recruited to CP.

189 -kappaB ligand (RANKL)-induced commitment of hemopoietic precursors to the osteoclastic lineage.

190 -induced functional damage to PHSC and other hemopoietic precursors, suggesting that improvements in

191 rovide protective immunity for recipients of hemopoietic progenitor cell transplants, but may cause g

192 n support the self-renewal of multipotential hemopoietic progenitor cells (MHPCs) is pertinent to und

193 In IL3-dependent hemopoietic progenitor cells (which express all four cla

194 The hierarchy of human hemopoietic progenitor cells that produce lymphoid and g

195 ) progeny of retrovirally transduced CD34(+) hemopoietic progenitor cells to stimulate responses agai

196 obust, and "dynamic" analysis of multipotent hemopoietic progenitor cells undergoing self-renewal in

197 Retroviral transduction of CD34(+) hemopoietic progenitor cells, during pre-expansion by th

198 igration and engraftment of human and murine hemopoietic progenitor cells, suggesting a cross-influen

199 cells but not in extracts of mobilized CD34+ hemopoietic progenitor cells.

200 blocking NF-kappaB activation in bone marrow hemopoietic progenitor cells.

201 ulting from an immune and cytokine attack on hemopoietic progenitor cells.

202 in vitro differentiation of mouse and human hemopoietic progenitor cells.

203 main-containing leukocyte protein of 76 kDa, hemopoietic progenitor kinase 1, and c-Cbl.

204 ly Mll(PTD/WT) FLC had increased pluripotent hemopoietic progenitors (CFU-GEMM).

205 hese cells can be produced from hESC-derived hemopoietic progenitors at a clonal frequency similar to

206 ed to reconstitute development of IL-7R(-/-) hemopoietic progenitors by transducing the receptors in

207 hroughout adult life, the thymus must import hemopoietic progenitors from the bone marrow via the blo

208 The nature of hemopoietic progenitors subject to leukemic transformati

209 E2A to rescue B lymphopoiesis from E2A(-/-) hemopoietic progenitors, although the N terminus of E2A,

210 ing activates T lineage differentiation from hemopoietic progenitors, but relatively few regulators t

211 duce the migration of resting leukocytes and hemopoietic progenitors.

212 thymic progeny, and 3) limited production of hemopoietic progeny other than thymocytes.

213 N-gamma-induced T-bet expression through the hemopoietic protein tyrosine phosphatase (PTP) Src homol

214 the nonhemopoietic (radioresistant) and the hemopoietic (radiosensitive) compartments, we measured b

215 proliferation both in vitro and in long term hemopoietic reconstitution in vivo.

216 nt from the mother led patient 1 to complete hemopoietic reconstitution, but only partial IFN-gammaR

217 infusion of purified CD4(+) T cells enhances hemopoietic recovery.

218 m impaired cytoreduction rather than delayed hemopoietic recovery.

219 th SDF-1alpha and Tac1 peptides are relevant hemopoietic regulators.

220 hma results from alterations in two distinct hemopoietic regulatory mechanisms.

221 This establishes IL-17A as a hemopoietic response cytokine to radiation injury in mic

222 in regulating host resistance as well as the hemopoietic response to intracellular pathogens.

223 The hemopoietic specific adapter protein ADAP (adhesion and

224 Previous evidence suggested that the hemopoietic-specific nuclear factor Ikaros regulates TCR

225 The hemopoietic-specific Rho family GTPase Rac2 shares 92% a

226 Vav1 is a hemopoietic-specific Rho/Rac guanine nucleotide exchange

227 The involvement of CD26/DPPIV in CD34(+) hemopoietic stem and progenitor cell migration has not b

228 Migration of hemopoietic stem and progenitor cells (HSPC) is required

229 Estrogen deficiency expands hemopoietic stem and progenitor cells (HSPCs) and mature

230 parathyroid hormone (iPTH) treatment expands hemopoietic stem and progenitor cells (HSPCs), but the i

231 ay represent a novel regulatory mechanism in hemopoietic stem and progenitor cells for the migration,

232 CXCL12/SDF-1alpha induces migration of hemopoietic stem and progenitor cells, and it is thought

233 F-beta is considered a negative regulator of hemopoietic stem and progenitor cells.

234 role that NK cells play in the rejection of hemopoietic stem cell (HSC) and tolerance induction has

235 acilitating cells (FC) significantly enhance hemopoietic stem cell (HSC) engraftment in allogeneic an

236 ecreted molecule derived from adipocytes, in hemopoietic stem cell (HSC) function.

237 Hemopoietic stem cell (HSC) transplantation using 500-50

238 ive properties, but its effects on primitive hemopoietic stem cell (PHSC) and early multilineage prec

239 et unknown serum factors in the aging of the hemopoietic stem cell compartment and possibly in organi

240 oplasms (MPNs) are a group of related clonal hemopoietic stem cell disorders associated with hyperpro

241 is, in fact, a positive regulator of murine hemopoietic stem cell function in vivo.

242 capable of providing signals that influence hemopoietic stem cell function.

243 etinoids are known to have potent effects on hemopoietic stem cell integrity, and our objective was t

244 2.R cells) that abrogate fully MHC-disparate hemopoietic stem cell rejection more effectively than co

245 d with conventional drug therapy, autologous hemopoietic stem cell transplantation (HSCT) can induce

246 a major problem for recipients of allogeneic hemopoietic stem cell transplantation (HSCT).

247 ous disease (CGD) can be cured by allogeneic hemopoietic stem cell transplantation (HSCT).

248 cultures for a cohort of patients undergoing hemopoietic stem cell transplantation and determined the

249 tic cells in CD8+ T cell-repleted allogeneic hemopoietic stem cell transplantation and prevented the

250 Therefore, unlike conventional drug therapy, hemopoietic stem cell transplantation generates a newly

251 inor histocompatibility Ag-mismatched murine hemopoietic stem cell transplantation models, whereas CD

252 In allogeneic hemopoietic stem cell transplantation, mature donor alph

253 ompatibility (H) Ags important in allogeneic hemopoietic stem cell transplantation, responses against

254 -leukemia (GvL) activity in murine models of hemopoietic stem cell transplantation.

255 ications limiting the efficacy of allogeneic hemopoietic stem cell transplantation.

256 lute numbers to those observed from parallel hemopoietic stem cell transplants, and provide a source

257 They are driven by mutations in the hemopoietic stem cell, most notably JAK2(V617F), CALR, a

258 isition of the tyrosine kinase BCR-ABL1 in a hemopoietic stem cell, transforming it into a leukemic s

259 In the present studies we evaluated which hemopoietic stem cell-derived components are critical to

260 Hemopoietic stem cell-derived mature Langerhans-type den

261 combination with c-kit(+)Sca-1(+)lineage(-) hemopoietic stem cells (HSC) and congenic donor T cells

262 -binding protein 1 (Id1) is not expressed in hemopoietic stem cells (HSC), but is increased in more c

263 rations constrain the in vivo study of human hemopoietic stem cells (HSC).

264 donor CD4+ T cells developed from engrafted hemopoietic stem cells (HSCs) in C57BL/6SJL(B6/SJL, H-2(

265 marrow that potently enhance engraftment of hemopoietic stem cells (HSCs).

266 Transplantation of purified allogeneic hemopoietic stem cells (SC) alone is characterized by a

267 f a humanized Npm1c knock-in allele in mouse hemopoietic stem cells causes Hox gene overexpression, e

268 Retroviral transduction of hemopoietic stem cells from TCR transgenic mice and subs

269 Immune destruction of hemopoietic stem cells plays an important role in pathog

270 Wild-type hemopoietic stem cells rapidly matured into functional T

271 ms of lymphoid and myeloid lineage choice by hemopoietic stem cells remain unclear.

272 (NOD) mice by reconstitution with autologous hemopoietic stem cells retrovirally transduced with viru

273 of NOD mice with pre-existing T1D autologous hemopoietic stem cells transduced with viruses encoding

274 nonirradiated recipient mice, we found that hemopoietic stem cells were excluded from the thymus, wh

275 late the thymus 9 days more rapidly than can hemopoietic stem cells, a rate of thymic repopulation ap

276 y of innate immune cells, of mesenchymal and hemopoietic stem cells, and insulin-releasing pancreatic

277 pulation, which is immediately downstream of hemopoietic stem cells, is heterogeneous and can be subd

278 MPP and common lymphoid progenitors but not hemopoietic stem cells.

279 e marrow (BM) cells bearing the phenotype of hemopoietic stem cells.

280 s regulated in part by survival/apoptosis of hemopoietic stem/progenitor cells.

281 a from chemotherapy, we investigated whether hemopoietic stroma induces resistance to Apo2L/TRAIL apo

282 bsent from any other IRF4+PU.1+ lymphoid and hemopoietic subsets.

283 f SDF-1alpha on Tac1 expression in the major hemopoietic supporting cells, the bone marrow stroma, an

284 LPS-mediated hemopoietic suppression requires two major inflammatory

285 e to LPS-induced septic shock as a result of hemopoietic suppression.

286 d inflammatory phenotype is intrinsic to the hemopoietic system and can be corrected by the re-expres

287 in which one or several cell lineages of the hemopoietic system are affected.

288 At baseline, the hemopoietic system of IL-17R knockout mice (IL-17Ra(-/-)

289 5-Fluorouracil subjects the hemopoietic system to acute stress and has the advantage

290 ytes in the regenerative capabilities of the hemopoietic system under the pressure of Pneumocystis in

291 ins and is expressed on myeloid cells of the hemopoietic system.

292 the management of a range of diseases of the hemopoietic system.

293 be a stochastic process particularly in the hemopoietic system.

294 ults in increased output of eosinophils from hemopoietic tissue in individuals with asthma.

295 del of TGF-beta insensitivity limited to the hemopoietic tissue of adult wild-type C57BL/6 mice based

296 exportation of waves of prothymocytes by the hemopoietic tissues in coordination with their gated imp

297 anscription signaling pathways in irradiated hemopoietic tissues supports these observations.

298 ver, when challenged with gamma irradiation, hemopoietic toxicity is significantly more pronounced in

299 frequent target for retroviral activation in hemopoietic tumors of avian and mammalian species.

300 ical trials have been initiated in solid and hemopoietic tumors such as CML, chronic lymphocytic leuk