ライフサイエンスコーパス: heparan sulfate proteoglycan

1 yndecan 4 as well as that of an unidentified heparan sulfate proteoglycan.

2 EGF188, that differ in their ability to bind heparan sulfate proteoglycan.

3 ers in the secretory pathway, namely LRP and heparan sulfate proteoglycan.

4 MuSK is activated by agrin, a neuron-derived heparan sulfate proteoglycan.

5 well as non-nucleic acid polyanions, such as heparan sulfate proteoglycan.

6 FGFR-1 but also syndecan-4, a transmembrane heparan-sulfate proteoglycan.

7 by T lymphocytes, TNF-like molecule 1A, and heparan sulfate proteoglycans.

8 cells requires its interaction with surface heparan sulfate proteoglycans.

9 creas), is in part dependent on sulfation of heparan sulfate proteoglycans.

10 ccurs after the initial binding of HMPV F to heparan sulfate proteoglycans.

11 TACI), and also interacts independently with heparan sulfate proteoglycans.

12 lphosphatidylinositol-anchored, cell-surface heparan sulfate proteoglycans.

13 lphosphatidylinositol-anchored, cell-surface heparan sulfate proteoglycans.

14 hesis, even after inhibition of sulfation of heparan sulfate proteoglycans.

15 its carboxyl terminus with lipoproteins and heparan sulfate proteoglycans.

16 lular trapping mediated by membrane-proximal heparan sulfate proteoglycans.

17 do not require cell surface sialic acids or heparan sulfate proteoglycans.

18 ion in vitro, which depended on cell-surface heparan sulfate proteoglycans.

19 inoglycans are the oligosaccharide chains of heparan sulfate proteoglycans.

20 conditions depends entirely on cell surface heparan sulfate proteoglycans.

21 -sulfation states of cell-surface and matrix heparan sulfate proteoglycans.

22 is modulated by extrinsic cofactors such as heparan sulfate proteoglycans.

23 ular attachment through binding cell surface heparan sulfate proteoglycans.

24 on through binding to integrin receptors and heparan sulfate proteoglycans.

25 sistent with a previously described role for heparan sulfate proteoglycans.

26 the endothelial receptors for IE binding are heparan sulfate proteoglycans.

27 Here, we focused on the syndecan-1 heparan sulfate proteoglycan, a highly conserved, multif

28 ary domains: a charged N terminus that binds heparan sulfate proteoglycans, a central NANP repeat dom

29 a conserved member of the glypican family of heparan sulfate proteoglycans, a family with several mem

30 was reduced approximately 60% by binding to heparan sulfate proteoglycans, a prominent component of

31 ng the MEK/ERK pathway is likely to modulate heparan sulfate proteoglycan activity, which in turn may

32 It is shown in this study that the heparan sulfate proteoglycan agrin is overexpressed in T

33 ine protease neurotrypsin, which cleaves the heparan sulfate proteoglycan agrin.

34 transduction activity requires cell surface heparan sulfate proteoglycans, although AAV(VR-942) lack

35 e two modules on Thy1(+) oval cells required heparan sulfate proteoglycan and integrin alpha(5)beta(1

36 Of the 11 well-characterized AAV serotypes, heparan sulfate proteoglycan and sialic acid have been s

37 nalization of Tat requires interactions with heparan sulfate proteoglycans and cholesterol-enriched l

38 Heparan sulfate proteoglycans and heparin derivatives fu

39 lpha C protein interaction involves multiple heparan sulfate proteoglycans and impairs bacterial kill

40 eins, thereby increasing viral attachment to heparan sulfate proteoglycans and inducing cell migratio

41 Heparin/heparan sulfate proteoglycans and neuropilin-1 (NRP-1) h

42 This DC-mediated transfer of HTLV-1 involves heparan sulfate proteoglycans and neuropilin-1 and resul

43 glucosamine 6-O-sulfate modifications within heparan sulfate proteoglycans and regulate their interac

44 by apoE's ability to bind with cell surface heparan sulfate proteoglycans and to lipoprotein recepto

45 tion of haptotactic gradients on endothelial heparan sulfate proteoglycans and, hence, integrin-media

46 senchyme, likely presented in the context of heparan sulfate proteoglycans, and effector molecules in

47 Angiogenin uptake into astroglia requires heparan sulfate proteoglycans, and engages clathrin-medi

48 trix may be dependent upon interactions with heparan sulfate proteoglycans, and these are likely to t

49 ation of MuSK by agrin, a neuronally derived heparan-sulfate proteoglycan, and LRP4 (low-density lipo

50 we demonstrate that surfen, a small molecule heparan sulfate proteoglycan antagonist, inhibits both S

51 Heparan sulfate proteoglycans are an important and abund

52 Heparan sulfate proteoglycans are critical binding partn

53 Heparan sulfate proteoglycans are essential for biologic

54 Heparan sulfate proteoglycans are ubiquitously located o

55 can-1, the predominant intestinal epithelial heparan sulfate proteoglycan, are essential in maintaini

56 Here, we identified heparan sulfate proteoglycan as a major cellular attachm

57 activity, GAG incorporation of (35)SO4, and heparan sulfate proteoglycan assembly.

58 Heparan sulfate proteoglycans bind to and regulate many

59 glycosophosphotidylinositol (GPI)-anchored, heparan-sulfate proteoglycans bind ligands of several ot

60 secretoneurin stimulates binding of VEGF to heparan sulfate proteoglycan binding sites.

61 ting effect of apoA-V has been attributed to heparan sulfate proteoglycan binding, as confirmed by st

62 ovel role for toutvelu (ttv), a regulator of heparan sulfate proteoglycan biosynthesis during this pr

63 of potential multistep processes involved in heparan-sulfate proteoglycans-bound FGF2 release, intern

64 boat, can mediate trans signaling through a heparan sulfate proteoglycan co-receptor in S2 cells.

65 HSulf-1 modulates the sulfation states of heparan sulfate proteoglycans critical for heparin bindi

66 monstrate a potential mechanism by which the heparan sulfate proteoglycan Dally-like (Dlp) promotes W

67 fects of RAP were significantly decreased in heparan sulfate proteoglycan-deficient Chinese hamster o

68 xclusive ligand of dendritic cell-associated heparan sulfate proteoglycan-dependent integrin ligand (

69 ered that the dendritic cell (DC)-associated heparan sulfate proteoglycan-dependent integrin ligand (

70 a patients express dendritic cell-associated heparan sulfate proteoglycan-dependent integrin ligand,

71 leagues show that dendritic cell-associated, heparan sulfate proteoglycans-dependent integrin ligand

72 We found that Glypican-3 (GPC3), a heparan sulfate proteoglycan expressed on murine as well

73 Glypicans are conserved cell surface heparan sulfate proteoglycans expressed in a spatiotempo

74 ze glycosaminoglycans, and more specifically heparan sulfate proteoglycans, for their attachment to h

75 e ectodomain shedding of syndecan-1, a major heparan sulfate proteoglycan found in epithelial cells.

76 enous hypertension, and the specific loss of heparan sulfate proteoglycans from the basolateral surfa

77 Conducted research showed that heparan sulfate proteoglycans function as adhesion molec

78 ems reflect the molecular characteristics of heparan sulfate proteoglycan functions observed previous

79 e includes only three characterized membrane heparan sulfate proteoglycan genes.

80 We previously found that the heparan sulfate proteoglycan glypican 1 (GPC1) is univer

81 The heparan sulfate proteoglycan Glypican 4 (Gpc4) is strong

82 roteoglycan neurocan, the growth-stimulating heparan sulfate proteoglycan glypican, or the chondroiti

83 The heparan sulfate proteoglycan glypican-1 (GPC1) is a core

84 The heparan sulfate proteoglycan glypican-1 (GPC1) is involv

85 vate EGL-mediated NO production and that the heparan sulfate proteoglycan glypican-1 is a primary mec

86 g protein on the Schwann cell surface is the heparan sulfate proteoglycan glypican-1.

87 The importance of heparan sulfate proteoglycans has been highlighted by a

88 d host glycosaminoglycan-anchoring proteins (heparan sulfate proteoglycans) has limited the understan

89 Syndecan 4, a heparan sulfate proteoglycan, has been associated with o

90 Glypican-3 (GPC3) is a cell-surface heparan sulfate proteoglycan highly expressed in hepatoc

91 Heparan sulfate proteoglycans (HS-PGs) regulate several

92 Indeed, expression of heparan sulfate proteoglycans (HS-PGs), normally involve

93 Two endocytic receptors, the syndecan-1 heparan sulfate proteoglycan (HSPG) and the LDL receptor

94 Binding of AAV to heparan sulfate proteoglycan (HSPG) at the ILM may allow

95 Glypican-3 (Gpc3) is a heparan sulfate proteoglycan (HSPG) expressed widely dur

96 ficient virus spread correlated largely with heparan sulfate proteoglycan (HSPG) expression on target

97 Heparan sulfate proteoglycan (HSPG) has also been implic

98 Heparan sulfate proteoglycan (HSPG) is required for this

99 emical studies implicate the presence of the heparan sulfate proteoglycan (HSPG) perlecan in islet am

100 odes the phylogenetically conserved secreted heparan sulfate proteoglycan (HSPG) perlecan, a componen

101 misrouting phenotype in mutants defective in heparan sulfate proteoglycan (HSPG) production and avoid

102 ine protease (SP) domains and bury potential heparan sulfate proteoglycan (HSPG) receptor binding res

103 ce lacking lipoprotein lipase (LPL), hepatic heparan sulfate proteoglycan (HSPG) receptors, LDLR, or

104 The heparan sulfate proteoglycan (HSPG) syndecan-1 (SDC1) ac

105 sion receptors, integrin alpha6beta1 and the heparan sulfate proteoglycan (HSPG) syndecan-4, triggeri

106 -2 mutants, which affect enzymes involved in heparan sulfate proteoglycan (HSPG) synthesis.

107 Although binding of CXCL12gamma to heparan sulfate proteoglycan (HSPG) was 10-fold higher t

108 l synaptogenesis, including the GPI-anchored heparan sulfate proteoglycan (HSPG) Wnt co-receptor Dall

109 attachment factors (HAFs), such as DC-SIGN, heparan sulfate proteoglycan (HSPG), and alpha4beta7 int

110 Dally-like (Dlp) is a glypican-type heparan sulfate proteoglycan (HSPG), containing a protei

111 e nonessential gC interact with cell surface heparan sulfate proteoglycan (HSPG), promoting viral att

112 To confirm this finding, we prepared heparan sulfate proteoglycan (HSPG)-knockout (KO) cells

113 sly shown to confer binding of the virion to heparan sulfate proteoglycan (HSPG).

114 its receptors, the proto-oncogene c-Met and heparan sulfate proteoglycan (HSPG).

115 accumulation is mediated through binding to heparan sulfate proteoglycans (HSPG) allowing for possib

116 It damages cell surface heparan sulfate proteoglycans (HSPG) and activates LOX-1

117 Here, we provide evidence of a novel role of heparan sulfate proteoglycans (HSPG) in the adaptive res

118 Binding to lipid and heparan sulfate proteoglycans (HSPG) induces apoE to ado

119 Heparan sulfate proteoglycans (HSPG) play a critical rol

120 Cleavage of heparan sulfate proteoglycans (HSPG) with heparinase III

121 y RTK pathways is regulated by extracellular heparan sulfate proteoglycans (HSPG), suggesting these m

122 step of virus-cell interaction by mimicking heparan sulfate proteoglycans (HSPG), the highly conserv

123 Heparan sulfate proteoglycans (HSPGs) act as binding rec

124 Heparan sulfate proteoglycans (HSPGs) act as coreceptors

125 Once released by HIV(+) cells, p17 binds heparan sulfate proteoglycans (HSPGs) and CXCR1 on leuko

126 bacterial surface binds to host cell surface heparan sulfate proteoglycans (HSPGs) and facilitates en

127 Binding studies with heparan sulfate proteoglycans (HSPGs) and neuropilin-1 (

128 enzyme that removes 6-O sulfate groups from heparan sulfate proteoglycans (HSPGs) and suppresses upt

129 We previously showed that HMPV binds heparan sulfate proteoglycans (HSPGs) and that HMPV bind

130 Because SULF1 and SULF2 desulfate heparan sulfate proteoglycans (HSPGs) and the HSPG glypi

131 xtracellular Hh binds to cell-bound glypican heparan sulfate proteoglycans (HSPGs) and the secreted p

132 Heparan sulfate proteoglycans (HSPGs) are central modula

133 Heparan sulfate proteoglycans (HSPGs) are concentrated a

134 Heparan sulfate proteoglycans (HSPGs) are extracellular

135 Heparan sulfate proteoglycans (HSPGs) are extracellular

136 Heparan sulfate proteoglycans (HSPGs) are found in the b

137 Heparan sulfate proteoglycans (HSPGs) are important modu

138 evious studies in Drosophila have shown that heparan sulfate proteoglycans (HSPGs) are involved in bo

139 Heparan sulfate proteoglycans (HSPGs) are normally assoc

140 Heparan sulfate proteoglycans (HSPGs) are potent regulat

141 Heparan sulfate proteoglycans (HSPGs) are required durin

142 In primary CD4(+) T cells, heparan sulfate proteoglycans (HSPGs) are required for e

143 Heparan sulfate proteoglycans (HSPGs) are synthesised an

144 Heparan sulfate proteoglycans (HSPGs) are ubiquitous com

145 Heparan sulfate proteoglycans (HSPGs) are ubiquitously e

146 Heparan sulfate proteoglycans (HSPGs) are used by a numb

147 nd that of others have identified syndecan-1 heparan sulfate proteoglycans (HSPGs) as remnant lipopro

148 Heparan sulfate proteoglycans (HSPGs) bind to and regula

149 O-sulfotransferases modify heparan sulfate proteoglycans (HSPGs) by catalyzing the

150 Heparan sulfate proteoglycans (HSPGs) control many cellu

151 Heparan sulfate proteoglycans (HSPGs) critically modulat

152 and distribution of Upd are regulated by the heparan sulfate proteoglycans (HSPGs) Dally and Dally-li

153 matosensory neurons as a model, we show that heparan sulfate proteoglycans (HSPGs) Dally and Syndecan

154 rough a similar ternary complex but requires heparan sulfate proteoglycans (HSPGs) for full activity.

155 of injury and repair in the lung, fragmented heparan sulfate proteoglycans (HSPGs) from damaged extra

156 Heparan sulfate proteoglycans (HSPGs) function as a co-r

157 Heparan sulfate proteoglycans (HSPGs) function as corece

158 In addition, heparan sulfate proteoglycans (HSPGs) have also been imp

159 Heparan sulfate proteoglycans (HSPGs) have been attribut

160 Cell surface heparan sulfate proteoglycans (HSPGs) have been implicat

161 Heparan sulfate proteoglycans (HSPGs) have long been imp

162 Heparan sulfate proteoglycans (HSPGs) have long unbranch

163 llenge model, we evaluated the importance of heparan sulfate proteoglycans (HSPGs) in human papilloma

164 The importance of heparan sulfate proteoglycans (HSPGs) in neurodevelopmen

165 sly explored the role of N-glycoproteins and heparan sulfate proteoglycans (HSPGs) in P. aeruginosa-m

166 e selectivity has been attributed to anionic heparan sulfate proteoglycans (HSPGs) in the glomerular

167 Heparan sulfate proteoglycans (HSPGs) influence the sign

168 Heparan sulfate proteoglycans (HSPGs) modulate the actio

169 terminal pro region is excreted and binds to heparan sulfate proteoglycans (HSPGs) of the basement me

170 indicates that prion protein aggregates bind heparan sulfate proteoglycans (HSPGs) on the cell surfac

171 o covalently attach to core proteins to form heparan sulfate proteoglycans (HSPGs) on the cell surfac

172 Heparan sulfate proteoglycans (HSPGs) play critical role

173 Heparan sulfate proteoglycans (HSPGs) regulate a number

174 We show that the Drosophila heparan sulfate proteoglycans (HSPGs) Syndecan (Sdc) and

175 Islet amyloid also contains heparan sulfate proteoglycans (HSPGs) that may contribut

176 any microbial pathogens subvert cell surface heparan sulfate proteoglycans (HSPGs) to infect host cel

177 stimulator of glioma growth, is regulated by heparan sulfate proteoglycans (HSPGs) via a ternary comp

178 Heparan sulfate proteoglycans (HSPGs), a class of glycos

179 wn to interfere with binding to cell surface heparan sulfate proteoglycans (HSPGs), also resulted in

180 Recently, a glucose transporter, GLUT-1, heparan sulfate proteoglycans (HSPGs), and neuropilin-1

181 transferases, a class of enzymes that modify heparan sulfate proteoglycans (HSPGs), are essential to

182 We demonstrated that expression of heparan sulfate proteoglycans (HSPGs), including TbetaRI

183 ein belonging to the heterogeneous family of heparan sulfate proteoglycans (HSPGs), is expressed by c

184 Heparan sulfate proteoglycans (HSPGs), located on the ce

185 We found levels of mRNAs encoding heparan sulfate proteoglycans (HSPGs), particularly SDC1

186 In contrast to the functional role of heparan sulfate proteoglycans (HSPGs), the importance of

187 ize glycosaminoglycans (GAGs), specifically, heparan sulfate proteoglycans (HSPGs), were resistant to

188 Epiblast-state transition in mESCs involves heparan sulfate proteoglycans (HSPGs), which have also b

189 LDL receptor (LDLR) family and cell-surface heparan sulfate proteoglycans (HSPGs), which have been s

190 uction by bridging the virus to cell-surface heparan sulfate proteoglycans (HSPGs).

191 as Hedgehog (Hh) and Wingless (Wg) depend on heparan sulfate proteoglycans (HSPGs).

192 his alters hepatic lipoprotein clearance via heparan sulfate proteoglycans (HSPGs).

193 n interact with the extracellular matrix and heparan sulfate proteoglycans (HSPGs).

194 aces of uninfected cells by interacting with heparan sulfate proteoglycans (HSPGs).

195 ally involves virion binding to cell surface heparan sulfate proteoglycans (HSPGs).

196 linked to core proteins collectively termed heparan sulfate proteoglycans (HSPGs).

197 cans comprise a major family of cell surface heparan sulfate proteoglycans (HSPGs).

198 ter hepatocytes in vivo through cell surface heparan sulfate proteoglycans (HSPGs).

199 thought to enter hepatocytes in vivo through heparan sulfate proteoglycans (HSPGs).

200 s with their receptors are often mediated by heparan sulfate proteoglycans (HSPGs).

201 vein (vn) and may influence binding of Vn to heparan-sulfated proteoglycans (HSPGs).

202 revealed that syndecan-4 (SD-4) is the sole heparan sulfate proteoglycan immunoprecipitated by DC-HI

203 Glypican-1 (Gpc1) is the predominant heparan sulfate proteoglycan in the developing and adult

204 wo glycosylphosphatidylinositol (GPI)-linked heparan sulfate proteoglycans in Drosophila.

205 gnaling and suggest a physiological role for heparan sulfate proteoglycans in the regulation of ephri

206 ccumulate through binding to highly specific heparan-sulfate proteoglycans in the extracellular matri

207 dent replication confirms a role for GPC5, a heparan sulfate proteoglycan, in disease risk.

208 we evaluated the role of syndecan-1, a major heparan sulfate proteoglycan, in modulating inflammatory

209 we evaluated the role of syndecan-1, a major heparan sulfate proteoglycan, in modulating multiorgan h

210 as well as aberrant cellular localization of heparan sulfate proteoglycans, in all subtypes.

211 ivation by binding dendritic cell-associated heparan sulfate proteoglycan-integrin ligand (DC-HIL) on

212 Agrin is a key heparan sulfate proteoglycan involved in the development

213 To investigate whether a heparan sulfate proteoglycan is involved in pipe functio

214 sulfate and that N- and 6-O-sulfation of the heparan sulfate proteoglycans is required for HCV infect

215 Interaction with heparan sulfate proteoglycans is supposed to provide che

216 The biosynthesis of heparan sulfate proteoglycans is tightly regulated by mu

217 a member of the mammalian glypican family of heparan sulfate proteoglycans, is highly expressed in gl

218 d ones bind heparin - a structural analog of heparan sulfate proteoglycans known to mediate exosome e

219 of integrin alpha(6)beta(1) and cell surface heparan sulfate proteoglycans, leading to ROS-dependent

220 Here we provide evidence that heparan sulfate proteoglycans may mediate binding betwee

221 These studies suggest that heparan sulfate proteoglycans may play a critical role i

222 evious studies have suggested alterations in heparan sulfate proteoglycan metabolism in rat and mouse

223 shedding of syndecan-1, a major cell surface heparan sulfate proteoglycan, modulates molecular and ce

224 in Caenorhabditis elegans, LON-2/glypican, a heparan sulfate proteoglycan, modulates UNC-6/netrin sig

225 Expression of SP-Tatm3x in heparan sulfate proteoglycan-negative cells further impr

226 how in this study that syndecan-1, the major heparan sulfate proteoglycan of epithelial cells, attenu

227 e binding of Wg to Dally, a potential target heparan sulfate proteoglycan of Sulf1.

228 ly dependent on the presence of cell surface heparan sulfate proteoglycans of acceptor cells.

229 on of DC-HIL, we hypothesized that a heparin/heparan sulfate proteoglycan on activated T cells is the

230 mation between FGF, FGF receptor (FGFR), and heparan sulfate proteoglycan on the cell membrane.

231 and Tec kinase, as well as membrane-proximal heparan sulfate proteoglycans on cell surfaces.

232 ) extracellular trapping of FGF2 mediated by heparan sulfate proteoglycans on cell surfaces.

233 ctoferrin was attributable to its binding to heparan sulfate proteoglycans on the cell surface of DA

234 All recombinant Tau assemblies bound heparan sulfate proteoglycans on the cell surface, which

235 L protein mediates attachment of virions to heparan sulfate proteoglycans on the surface of hepatocy

236 ances LPL cleavage in the presence of either heparan sulfate proteoglycans or glycosylphosphatidylino

237 llografts, selective induction of the matrix heparan sulfate proteoglycan perlecan was observed, alon

238 in, the angiostatic C-terminal domain of the heparan sulfate proteoglycan perlecan, inhibits angiogen

239 Endorepellin, the C-terminal fragment of the heparan sulfate proteoglycan perlecan, possesses angiost

240 t cell lines, RBL-2H3 and HMC-1, produce the heparan sulfate proteoglycan, perlecan, with a molecular

241 ), which is bound to the pericellular matrix heparan sulfate proteoglycan, perlecan.

242 vide the first genetic evidence that hepatic heparan sulfate proteoglycans play a central role in the

243 der normal physiological conditions, hepatic heparan sulfate proteoglycans play a crucial role in the

244 Syndecan 1 is a major heparan sulfate proteoglycan present on many host cells

245 by high expression of syndecan-1 (CD138), a heparan sulfate proteoglycan present on the myeloma cell

246 Heparan sulfate proteoglycans, present on cell surfaces

247 Syndecan-1 is a cell surface heparan sulfate proteoglycan primarily expressed in the

248 d, Saez et al demonstrate that inhibition of heparan sulfate proteoglycan production by bone marrow o

249 ociated with mutations in genes encoding for heparan sulfate proteoglycan protein cores or biosynthet

250 suggesting that Pipe-mediated sulfation of a heparan sulfate proteoglycan provides a spatial cue for

251 r mediating the interaction of AAV2 with the heparan sulfate proteoglycan receptor.

252 air depends on interactions between cellular heparan sulfate proteoglycan receptors, syndecan-1 and -

253 t or dynamin activity or remove cell surface heparan sulfate proteoglycans reduced infection efficien

254 kdown of glycosaminoglycan polymerases or of heparan sulfate proteoglycans reduced the cellular bindi

255 Transmembrane heparan sulfate proteoglycans regulate multiple aspects

256 Heparan sulfate proteoglycans regulate various physiolog

257 Previous studies showed that Dally, a heparan sulfate proteoglycan, regulates both the distrib

258 Heparan sulfate proteoglycan(s) is present in neutrophil

259 es the interaction between TGF-beta1 and its heparan sulfate proteoglycan sequestration receptor, TGF

260 neuronal connectivity, recent studies of the heparan sulfate proteoglycans suggest that these ancient

261 iciency screen to identify the transmembrane heparan sulfate proteoglycan Syndecan (Sdc) as a ligand

262 t this activity requires the shedding of the heparan sulfate proteoglycan syndecan-1 (Sdc1) from the

263 The induction of the cell surface heparan sulfate proteoglycan syndecan-1 (Sdc1) in stroma

264 When shed from the cell surface, the heparan sulfate proteoglycan syndecan-1 can facilitate t

265 Furthermore, we identified the heparan sulfate proteoglycan syndecan-1 in complexes wit

266 The heparan sulfate proteoglycan syndecan-1 is expressed by

267 The cell surface heparan sulfate proteoglycan syndecan-1 is induced in st

268 The heparan sulfate proteoglycan syndecan-1 is proteolytical

269 We recently showed that the heparan sulfate proteoglycan syndecan-1 mediates hepatic

270 ncreasing the expression and shedding of the heparan sulfate proteoglycan syndecan-1, a molecule know

271 s have shown that postsynaptic expression of heparan sulfate proteoglycan syndecan-2 (SDC2) induces d

272 The interaction of TG2 with the heparan sulfate proteoglycan syndecan-4 (Sdc4) regulates

273 n sulfate (HS)/heparin and reported that the heparan sulfate proteoglycan syndecan-4 acts as a recept

274 The heparan sulfate proteoglycan syndecan-4 is important in

275 nascin-C, was dependent on expression of the heparan sulfate proteoglycan syndecan-4, which also bind

276 The cell surface heparan sulfate proteoglycan, syndecan-1, has been repor

277 ia low density lipoprotein receptors and the heparan sulfate proteoglycan, syndecan-1.

278 Syndecan-2 is a heparan sulfate proteoglycan that has a cell adhesion re

279 Syndecan-2 is a heparan sulfate proteoglycan that is known to be importa

280 wth factors (HBGFs) and glypican-1 (GPC1), a heparan sulfate proteoglycan that promotes efficient sig

281 ne copy of GPC1, which encodes glypican 1, a heparan sulfate proteoglycan that regulates Hedgehog sig

282 Syndecans are a family of four transmembrane heparan sulfate proteoglycans that act as coreceptors fo

283 Glypicans are heparan sulfate proteoglycans that are bound to the cell

284 cur in a manner dependent on the presence of heparan sulfate proteoglycans that are expressed ubiquit

285 Heparin, an analog of the heparan sulfate proteoglycans that are receptors for den

286 Glypicans are heparan sulfate proteoglycans that modulate the signalin

287 the enzyme heparanase (HPSE), which degrades heparan sulfate proteoglycans, the main components of EC

288 inding domain that mediates interaction with heparan sulfate proteoglycans, thereby targeting LPA pro

289 , the light chains caused a translocation of heparan sulfate proteoglycan to the nucleus.

290 of HPV type 16 (HPV16) (pseudo)virions with heparan sulfate proteoglycans triggers a conformational

291 he PSC requires expression of the Dally-like heparan-sulfate proteoglycan, under the control of the C

292 In addition, eliminating heparan sulfate proteoglycans using heparinase completel

293 The direct Ad binding to hepatic heparan sulfate proteoglycans via the KKTK motif within

294 olecule-3-grabbing nonintegrin (DC-SIGN) and heparan sulfate proteoglycan were implicated as corecept

295 rosarcoma and a murine osteoblast cell line, heparan sulfate proteoglycans were identified as the cel

296 Ps Dpp and Gbb through its Vg domain, and to heparan sulfate proteoglycans, which are well-known for

297 T beta RIII is a heparan sulfate proteoglycan with a short cytoplasmic ta

298 hanosensitive complex contains an endogenous heparan sulfate proteoglycan with HS chains that is crit

299 We review recent genetic evidence that heparan sulfate proteoglycans work in concert with the L

300 modifications of glycosaminoglycan chains on heparan sulfate proteoglycans, yet their biological func