ライフサイエンスコーパス: hepatic clearance

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1 rt by their short half-life due to excessive hepatic clearance.

2 stabsorptive rates and that avoid first-pass hepatic clearance.

3 of drugs, especially with low or negligible hepatic clearance.

4 cilitating glucocorticoid production and LPS hepatic clearance.

5 gent from the blood was used as a measure of hepatic clearance.

6 eas in MODY3 patients may be due to impaired hepatic clearance and elevated plasma concentrations of

7 ing first-pass elimination in the liver, and hepatic clearance) and systemic exposure (i.e., CFA) of

8 action unbound in plasma (fup) and intrinsic hepatic clearance (CLint) parameters were estimated in s

9 The average hepatic clearance fraction in the two-compartment model

10 ion of CEA (PELPK motif) responsible for its hepatic clearance in three of eight patients with high C

11 Hepatic clearance involves the LDL receptor (LDLR) and p

12 of TG-rich lipoproteins primarily through a hepatic clearance mechanism mediated by the LDLR/LRP1 ax

13 r-bearing mice despite lack of saturation of hepatic clearance mechanisms.

14 suggesting the possibility of rapid in vivo hepatic clearance mediated by oxidative metabolism.

15 Hepatic clearance of (99m)Tc-mebrofenin was studied with

16 Type 2 diabetes mellitus (T2DM) impairs hepatic clearance of atherogenic postprandial remnant li

17 Type 2 diabetes mellitus (T2DM) impairs hepatic clearance of atherogenic postprandial triglyceri

18 The hepatic clearance of atRA is mediated primarily by CYP26

19 ct in a gene other than NTCP that influences hepatic clearance of bile salts.

20 x from peripheral cells as well as the rapid hepatic clearance of FC from plasma HDL.

21 Intrinsic hepatic clearance of fluorescent bile acids (2-7 mL/g li

22 Hepatic clearance of fVIII is mediated by the LDL recept

23 severe hypercholesterolemia due to impaired hepatic clearance of LDL.

24 Hepatic clearance of remnants occurs via low density lip

25 eins into BAT, subsequently accelerating the hepatic clearance of the cholesterol-enriched remnants.

26 tivate blood-borne thrombin leading to rapid hepatic clearance of the thrombin-inhibitor complex.

27 Hepatic clearance of triglyceride-rich lipoproteins depe

28 ran sulfate proteoglycan syndecan-1 mediates hepatic clearance of triglyceride-rich lipoproteins in m

29 Both renal and hepatic clearance pathways were observed.

30 correction for potential binding effects on hepatic clearance provided the most accurate predictions

31 In this study, we measured in vitro hepatic clearance rates for 50 IOCs using a pooled batch

32 Thus, multiple hepatic clearance receptors cooperate to eliminate secre

33 Inhibition of known glycan-recognizing hepatic clearance receptors showed involvement of multip

34 metastases and elevated liver enzymes (rapid hepatic clearance with liberation of free I-).

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