ライフサイエンスコーパス: hepatic stem cell

1 y is the use of multiple definitions for the hepatic stem cell.

2 biology have intersected at the study of the hepatic stem cell.

3 xpressed in embryonic livers and in isolated hepatic stem cells.

4 normal activation and proliferation of adult hepatic stem cells.

5 During the hepatic stem cell activation (2-acetylaminofluorene/part

6 development of nonalcoholic steatohepatitis, hepatic stem cell activation, and hepatocarcinogenesis i

7 ulations can occur in diseases; for example, hepatic stem cell amplification occurs in mild forms of

8 In adult livers, intermediates between hepatic stem cells and hepatoblasts and between hepatobl

9 livers contain two pluripotent progenitors: hepatic stem cells and hepatoblasts.

10 Hepatic stem cells are activated after liver damage and

11 The hepatic stem cells are located in vivo in stem cell nich

12 Hepatic stem cells are located within canals of Hering a

13 hat hepatic stellate cells may contribute to hepatic stem cell behavior, cancer, and regeneration.

14 for biliary-type cytokeratins, may represent hepatic stem cells, canals of Hering (CoH), and/or ducta

15 The existence of a facultative hepatic stem cell compartment in bile ductules that part

16 ed during activation of the normally dormant hepatic stem cell compartment.

17 close relationship between BDE cells and the hepatic stem-cell compartment.

18 r characterizing the cellular biology of the hepatic stem-cell compartment.

19 ultures, which might contain a population of hepatic stem cells, constitute an excellent tool for a v

20 transcription factors at different stages of hepatic stem cell differentiation.

21 ulture system have relevance for identifying hepatic stem cells from adults, for studying liver devel

22 Isolation of hepatic stem cells from the adult liver (AL) has not yet

23 tudies to identify, characterize and isolate hepatic stem cells from the AL.

24 no specific marker gene unique to the adult hepatic stem cell has yet been identified, and regenerat

25 y, the very question of the existence of the hepatic stem cell has yet to be unequivocally establishe

26 as or be a source of bipotential facultative hepatic stem cells (hepatoblasts).

27 ve been devised for transplantation of human hepatic stem cells (hHpSCs) embedded into a mix of solub

28 lity in driving the differentiation of human hepatic stem cells (hHpSCs) into adult liver fates.

29 Human hepatic stem cells (hHpSCs), seeded onto liver biomatrix

30 Human hepatic stem cells (hHpSCs), which are pluripotent precu

31 To activate oval cells, the hepatic stem cell (HSC) progeny, we used a model of live

32 dult HCs), fetal liver cells (FLCs), induced hepatic stem cells (iHepSCs) and bone marrow derived mes

33 ilar to that seen during early activation of hepatic stem cells in adult liver.

34 systems associated with early activation of hepatic stem cells in bile duct proliferation was also e

35 , the CoH consist of, or harbor, facultative hepatic stem cells in humans.

36 The involvement of hepatic stem cells in liver regeneration under certain c

37 dent with bromodeoxyuridine to load possible hepatic stem cells in mice with label and then administe

38 recursors to hepatoblasts, which differ from hepatic stem cells in size, morphology, and in expressin

39 ental evidence supporting the involvement of hepatic stem cells in the pathogenesis of liver cancers,

40 ification of oval cells (presumed progeny of hepatic stem cells) in a variety of biliary and nonbilia

41 EpCAM (epithelial cell adhesion molecule, a hepatic stem cell marker) expression.

42 Recently, we have identified that a hepatic stem cell marker, epithelial cell adhesion molec

43 developing embryo, and EpCAM, a cell surface hepatic stem cell marker.

44 Notably, perivascular tumor cells expressed hepatic stem cell markers.

45 certain physiologic conditions, a portion of hepatic stem cells might arise from the bone marrow and

46 Progressive activation of the mouse hepatic stem cell niche in response to ALIOS correlated

47 Four possible hepatic stem cell niches are identified by this approach

48 been made in the identification of potential hepatic stem cell niches.

49 ential cell surface markers for murine fetal hepatic stem cells, of which Nope may be particularly us

50 Adult hepatic stem cells or oval cells are facultative stem ce

51 Proliferation and differentiation of hepatic stem cell progenies (i.e., oval cells) sustain l

52 They behave like hepatic stem cells/progenitors with dual phenotype, exhi

53 he idea that CD34 might also be expressed on hepatic stem cell progeny.

54 AHR activation have been evaluated on rodent hepatic stem cells (rHpSCs) versus their descendants, he

55 Oval cells are resident hepatic stem cells that promote liver regeneration and r

56 The derivation of hepatic stem cells, the roles of HFE protein and other h

57 ago that the adult mammalian liver contains hepatic stem cells, this issue remains controversial.

58 The hepatic stem cells uniquely express the combination of e

59 To identify new surface markers for hepatic stem cells, we analyzed differences in the gene