ライフサイエンスコーパス: heterocomplex

1 that may drive the formation of the ternary heterocomplex.

2 ted a stable salt-resistant chaperone-client heterocomplex.

3 a subset of AUF1 proteins that interact in a heterocomplex.

4 in vivo identification of the RAD51B/RAD51C heterocomplex.

5 the existence of an endogenous RAD51B/RAD51C heterocomplex.

6 correlated with the presence of a c-Src/HER2 heterocomplex.

7 eractions within the hsp90-kinase-p50(cdc37) heterocomplex.

8 anism is formation of a cross-class receptor heterocomplex.

9 nredundant functional role forming in vivo a heterocomplex.

10 that mediated by the TbetaR-I and TbetaR-II heterocomplex.

11 sing in Escherichia coli to an active enzyme heterocomplex.

12 p90 to block formation of the p23.hsp90.FKBP heterocomplex.

13 by formation of a functional receptor-hsp90 heterocomplex.

14 8, and 11 also contribute to a less abundant heterocomplex.

15 agment Pih1(1-195) is able to bind Rvb1/Rvb2 heterocomplex.

16 nd FGFR1c consistent with formation of a 1:1 heterocomplex.

17 8s, Klp5 and Klp6, which associate to form a heterocomplex.

18 ate in the absence of a functional hsp90-p23 heterocomplex.

19 th a heat shock protein (Hsp)90 multiprotein heterocomplex.

20 SH5 promotes the dissociation of hMSH4-hMSH5 heterocomplex.

21 -dependent remodeling of the BAG2-Hsc70-CHIP heterocomplex.

22 pithelium, prevents formation of the protein heterocomplex.

23 or stabilize high-affinity chaperone-client heterocomplexes.

24 of p50(cdc37) associated with Hsp90/PP5-HRI heterocomplexes.

25 y found associated with protein kinase.hsp90 heterocomplexes.

26 assembles glucocorticoid receptor (GR).hsp90 heterocomplexes.

27 sembly of glucocorticoid receptor (GR).Hsp90 heterocomplexes.

28 cyte lysate, which also assembles nNOS.hsp90 heterocomplexes.

29 hat forms glucocorticoid receptor (GR).hsp90 heterocomplexes.

30 ons, determines the assembly of stable hsp90 heterocomplexes.

31 ere much less stable than wild-type GR.hsp90 heterocomplexes.

32 not present in native steroid receptor.hsp90 heterocomplexes.

33 and increases retinoic acid occupancy of the heterocomplexes.

34 semble steroid receptors into receptor.hsp90 heterocomplexes.

35 PMD1 and PMD2 can form homo- and heterocomplexes.

36 neutrophil granules as well as S100A8/A9, a heterocomplex abundant in neutrophil cytosol.

37 The beta-catenin.alphaT-catenin heterocomplex also binds F-actin with high affinity unli

38 ent human serum showed that free circulating heterocomplexes also exist in the blood, although the ma

39 sis, binds relatively poorly to the purified heterocomplexes, although it binds with high affinity to

40 such a co-chaperone that remodels the Hsp90 heterocomplex and causes protein degradation of some Hsp

41 rventions through regulation of the Hsp90-GR heterocomplex and focal prevention of GR signaling in se

42 r pouches and injured muscles depends on the heterocomplex and is inhibited by AMD3100 and glycyrrhiz

43 elucidate the function of the RAD51B/RAD51C heterocomplex and its association with the other RAD51 p

44 n-p23 complex, counteracting assembly of the heterocomplex and repression of hHSF1 transcriptional ac

45 insight into a type I transmembrane receptor heterocomplex and the mechanism of integrin inside-out t

46 cocorticoid receptor (GR) to form a GR.hsp90 heterocomplex and to convert the receptor ligand binding

47 assembles glucocorticoid receptor (GR).hsp90 heterocomplexes and causes the simultaneous opening of t

48 assembles glucocorticoid receptor (GR).hsp90 heterocomplexes and causes the simultaneous opening of t

49 assembles glucocorticoid receptor (GR).hsp90 heterocomplexes and causes the simultaneous opening of t

50 in promoting both assembly of receptor-hsp90 heterocomplexes and conversion of receptor to the steroi

51 WRKY proteins formed both homocomplexes and heterocomplexes and DNA binding activities were signific

52 ecreased ability to assemble stable GR.hsp90 heterocomplexes and generate stable steroid binding acti

53 ssential for the formation of receptor.Hsp90 heterocomplexes and GR folding.

54 P52 is a component of steroid receptor.hsp90 heterocomplexes, and it binds to hsp90 via a region cont

55 es the RalBP1 x HSF1 x HSP90 x alpha-tubulin heterocomplexes, and translocates into the nucleus, wher

56 dependent growth promoted by the ErbB2/ErbB3 heterocomplex are dependent upon c-Src, as demonstrated

57 y, two previous models on the formation of a heterocomplex are incompatible with our observations and

58 tranded DNA-binding protein Cdc13 and the Ku heterocomplex are known to participate in native telomer

59 Similarly, STAT1-STAT3 heterocomplexes are coimmunoadsorbed from hypotonic cyto

60 GR.hsp90 heterocomplexes are formed by a multiprotein system that

61 lex mechanism, where both receptor homo- and heterocomplexes are formed.

62 lia of kidney, thyroid, and liver, MCT/CD147 heterocomplexes are localized in the basolateral membran

63 d from L cell cytosol, it is in the GR.hsp90 heterocomplex assembled in reticulocyte lysate.

64 affect assembly, it is recovered in GR.hsp90 heterocomplexes assembled by both systems.

65 ell cytosol contain dynein and that GR.hsp90 heterocomplexes assembled in reticulocyte lysate contain

66 o show that Hop is not required for GR.Hsp90 heterocomplex assembly and activation of steroid binding

67 e same ability to carry out dynamic GR.hsp90 heterocomplex assembly as wild-type cytosol.

68 y incubating the washed GR with [3H]TA after heterocomplex assembly at 30 degrees C.

69 ain; furthermore, it also changes GSK3beta's heterocomplex assembly by associating with the phosphata

70 rm with corresponding inhibition of GR.hsp90 heterocomplex assembly by the minimal five-protein chape

71 Using both direct assay of heterocomplex assembly by Western blotting and indirect

72 he commonly accepted model of receptor-hsp90 heterocomplex assembly in which the chaperone initially

73 s, hsp70 is continuously bound by BAG-1, and heterocomplex assembly is blocked.

74 When cells are stressed, heterocomplex assembly is disrupted.

75 Retention by plants of the entire heterocomplex assembly machinery for linking the GR to d

76 five-protein system does not affect GR.hsp90 heterocomplex assembly or the activation of steroid bind

77 functions in the rabbit reticulocyte lysate heterocomplex assembly system and human p23 functions in

78 PRs) component of the steroid receptor.hsp90 heterocomplex assembly system bind very tightly to hsp90

79 ed proteins, we have prepared a five-protein heterocomplex assembly system consisting of two proteins

80 hsp90 heterocomplex assembly, but a complete heterocomplex assembly system has never been reconstitut

81 atography and then reconstitute the GR.hsp90 heterocomplex assembly system in a manner that requires

82 The effect of p23 in the minimal GR heterocomplex assembly system is to stabilize GR.hsp90 h

83 A minimal GR.hsp90 heterocomplex assembly system was reconstituted with pur

84 ntly, we have reconstituted a receptor.hsp90 heterocomplex assembly system with purified rabbit hsp90

85 ntly, we have reconstituted a receptor.hsp90 heterocomplex assembly system with purified rabbit hsp90

86 f this apparently ubiquitous protein folding/heterocomplex assembly system.

87 6 knockdown cytosol restores stable GR.hsp90 heterocomplex assembly to the level of wild-type cytosol

88 However, in contrast to the GR, heterocomplex assembly with hsp90 is not required for in

89 pha on transcriptional activation, the hsp90 heterocomplex assembly, and hsp90-dependent nuclear tran

90 PR) domains, it is not required for GR.hsp90 heterocomplex assembly, and it is thought to play a role

91 of steroid binding activity that occurs with heterocomplex assembly, and three proteins, Hop, hsp40,

92 be required for progesterone receptor.hsp90 heterocomplex assembly, but a complete heterocomplex ass

93 tem consisting of two proteins essential for heterocomplex assembly-hsp90 and hsp70-and three protein

94 binding domain that is required for GR.hsp90 heterocomplex assembly.

95 s have rejected any role for Hop in GR.hsp90 heterocomplex assembly.

96 chaperone system without inhibiting GR.hsp90 heterocomplex assembly.

97 ption did not affect GR folding and GR.hsp90 heterocomplex assembly.

98 e effect of BAG-1 on GR folding and GR.hsp90 heterocomplex assembly.

99 aperone system where it potentiates GR.hsp90 heterocomplex assembly.

100 and it does not appear to affect the rate of heterocomplex assembly.

101 ylation of hsp90 results in dynamic GR.hsp90 heterocomplex assembly/disassembly, and this is manifest

102 ssembly of the glucocorticoid receptor-hsp90 heterocomplex at an intermediate state of assembly where

103 one Hip has been recovered in receptor.hsp90 heterocomplexes at an intermediate stage of assembly in

104 eterotetrameric structure of native receptor heterocomplexes being 1 molecule of receptor, 2 molecule

105 Once mixing has taken place, formation of a heterocomplex between betaB1- and betaA3-crystallins is

106 Although the native heterocomplex between hsp90 and p50(cdc37) is salt-labil

107 er, by co-immunoprecipitation experiments, a heterocomplex between N. crassa HET-C1 and PhcA was asso

108 We hypothesized that heterocomplexes between ficolin-1 and PTX3 might mediate

109 ggest a mechanism involving the formation of heterocomplexes between HSF1 and HSF2 with enhanced acti

110 AP1 and AG homocomplexes and AP3-PI heterocomplexes bind to CArG-box sequences.

111 immediate dissociation of the cytoplasmic GR heterocomplex, binding of hormone-induced substitution o

112 Unlike other DnaJs, Tid1-L and -S form heterocomplexes; both unassembled and complexed Tid1 are

113 These two proteins form a heterocomplex, but not a homocomplex.

114 otein with high affinity sites for pZPB-pZPC heterocomplexes, but not free glycoprotein subunits.

115 with comparable affinity to CRABP-I and the heterocomplexes, but with approximately 10-fold less aff

116 tially forms heterodimers with Mlx, and this heterocomplex can bind to, and activate transcription fr

117 recognition is mediated by the presence of a heterocomplex composed of polypeptides encoded by het-c

118 ceptor homodimer and tissue protection via a heterocomplex composed of the EPO receptor and CD131, th

119 plex with M protein after synthesis, whereas heterocomplexes consisting of all three proteins formed

120 nly HE dimers were found associated with the heterocomplexes consisting of all three proteins.

121 we report that TNF induces the formation of heterocomplexes consisting of both p55 and p75 TNF recep

122 ndetermined) fraction of the native GR.hsp90 heterocomplexes contain the cyclosporin A-binding immuno

123 These receptor heterocomplexes contain wheat FKBPs, and they bind rabbi

124 Here, we show that CyP-A exists in native heterocomplexes containing cytoplasmic dynein that can b

125 glucocorticoid receptors (GR) exist as large heterocomplexes containing hsp90 bound to TPR proteins,

126 Here we report crystal structures of heterocomplexes containing mammalian R2 C-terminal hepta

127 CyP-A heterocomplexes containing tubulin and dynein can be for

128 sp70) assembly system inhibits both receptor heterocomplex disassembly and loss of steroid binding ac

129 isms, transcriptionally repressed HSF1.HSP90 heterocomplexes dissociate following stress, which trigg

130 ulfide bonds, the formation of the XXT2-XXT5 heterocomplex does not involve covalent interactions.

131 ering normal PAR proteins into nonfunctional heterocomplexes (dominant-negative interference).

132 ndense multiple intact TRAP rings into large heterocomplexes, effectively reducing the available cont

133 not found to be associated with the AhR-Arnt heterocomplex either in vitro or in nuclear extracts iso

134 Dissection of heterocomplex energetic components reveals a crucial rol

135 repeat (TPR) domain, and different receptor heterocomplexes exist depending upon which immunophilin

136 We demonstrate here that STAT protein heterocomplexes exist prior to cytokine treatment.

137 ating that Wee1, Mik1 and Swe1 require Hsp90 heterocomplexes for their stability and maintenance of f

138 results demonstrate that ficolin-1 and PTX3 heterocomplex formation acts as a noninflammatory "find

139 residues M10 or T11 but K60 is essential for heterocomplex formation and Cu transfer.

140 naling by MDA5 and RIG-I, presumably through heterocomplex formation and/or by serving as a sink for

141 Receptor heterocomplex formation in animal lysates and in the pla

142 Ficolin-1 and PTX3 heterocomplex formation occurred on dying host cells, bu

143 that overexpressed wild-type c-Src enhances heterocomplex formation of ErbB2 and ErbB3 that results

144 The heterocomplex formation was a prerequisite for enhanceme

145 We assessed the heterocomplex formation with ELISA, size-exclusion chrom

146 ce of a critical alpha-helical structure and heterocomplex formation with hsp90 but eliminates steroi

147 binding modes are observed in both homo- and heterocomplex formation with minimal change in helix axi

148 mily is required for substrate targeting and heterocomplex formation with other chaperones, but mutan

149 g membrane fusion, ion channel activity, and heterocomplex formation with other proteins.

150 hypothesized that MAP-1 is also involved in heterocomplex formation with the MASPs thereby breaking

151 Furthermore, GRo.hsp90 heterocomplexes formed in vivo or assembled under cell-f

152 peptide repeat-containing component of Hsp90 heterocomplexes found to be essential for cell viability

153 First, we show that p53.hsp90 heterocomplexes from DLD-1 human colon cancer cells cont

154 how that p50(cdc37) exists in separate hsp90 heterocomplexes from the TPR domain proteins and that in

155 es stable glucocorticoid receptor (GR)-hsp90 heterocomplexes has been reconstituted from reticulocyte

156 both receptor-hsp90 and protein kinase-hsp90 heterocomplexes have been carried out with the protein-f

157 r knowledge, model for the transient ternary heterocomplex, i.e., a TrkA/NGF/p75(NTR) ligand/receptor

158 ur-protein complex will form stable GR.Hsp90 heterocomplexes if p23 is added to the system.

159 is observed with a variety of protein kinase heterocomplexes immunoadsorbed from cytosols.

160 Here, we also show that native GR.hsp90 heterocomplexes immunoadsorbed from L cell cytosol conta

161 show that addition of p23 to native GR.hsp90 heterocomplexes immunoadsorbed from L cell cytosol or to

162 p23 stabilizes the GR.hsp90 heterocomplex in a dynamic and ATP-independent manner.

163 ense mutations disrupt the formation of this heterocomplex in in vitro interaction assays.

164 About half of each protein was detected in a heterocomplex in logarithmically growing yeast.

165 reatment of mice with ezetimibe disrupts the heterocomplex in only hypercholesterolemic animals.

166 mphasizing the functional importance of this heterocomplex in p53 control.

167 isms, PfClpP and PfClpR do not form a stable heterocomplex in the apicoplast of P. falciparum.

168 of disassembly of the triple mutant GR.hsp90 heterocomplex in the cell.

169 exists as a molybdate-stabilized nNOS.hsp90 heterocomplex in the cytosolic fraction of human embryon

170 ors by being part of a FGFR1-5-HT1A receptor heterocomplex in the midbrain raphe 5-HT nerve cells app

171 y of c-Src and EGFR to form an EGF-dependent heterocomplex in vivo.

172 the GR with hsp90.p60.hsp70 forms a GR.hsp90 heterocomplex in which hsp90 is in an ATP-dependent conf

173 e Tpr2 was not detected as a component of PR heterocomplexes in cell lysates, purified Tpr2 bound the

174 uronal glucose transporter GLUT3 do not form heterocomplexes in human embryonic kidney 293 (HEK293) c

175 Approximately one-half of the GR.hsp90 heterocomplexes in L cell cytosol contains an immunophil

176 determines a major portion of the native GR heterocomplexes in L cell cytosol.

177 edicted signal peptide sequence formed HET-C heterocomplexes in the cytoplasm and showed a growth arr

178 e for the existence of FGFR1-5-HT1A receptor heterocomplexes in the dorsal and median raphe nuclei of

179 pr2 promoted the accumulation of Hsp70 in PR heterocomplexes in the presence of Hsp90.

180 nd HSP90 are also present in the RalBP1.HSF1 heterocomplexes in unstressed cells.

181 forms) can bind to satellite DNA as homo- or heterocomplexes in vitro.

182 e data suggest that KLB and FGFR1 form a 1:1 heterocomplex independent of the galectin lattice that t

183 1c, suggesting that the two receptors form a heterocomplex independent of the galectin lattice.

184 eins, CRABP-I and CRABP-II, and the purified heterocomplexes indicate that all-trans-retinoic acid bi

185 The Nop56/58-fibrillarin heterocomplex is a core protein complex of the box C/D r

186 The resulting heterocomplex is a surprisingly compact structure, featu

187 assembly of a glucocorticoid receptor-hsp90 heterocomplex is brought about in reticulocyte lysate by

188 ent manner, and hsp90 in the hsp90.p60.hsp70 heterocomplex is in a conformation that does not bind p2

189 This heterocomplex is then translocated into the nucleus, whe

190 he components of the 5-HT(2A).mGlu2 receptor heterocomplex is up-regulated in the frontal cortex of s

191 nophilin component of steroid receptor.hsp90 heterocomplexes is accompanied by coadsorption of cytopl

192 Although hsp40 is not in the final GR.hsp90 heterocomplex isolated from L cell cytosol, it is in the

193 GR.hsp90 heterocomplexes isolated from cells contain one of sever

194 tain dynamitin as well as dynein and that GR heterocomplexes isolated from cytosol containing paclita

195 phate) completely prevented formation of the heterocomplex (Kd > 100 nM).

196 activity requires activation by a chaperone heterocomplex like that required for activation of the v

197 The HET-C heterocomplex localized to the plasma membrane (PM); PM-

198 p50 component of the Src.hsp90 and Raf.hsp90 heterocomplexes localizes to cytoskeletal fibers extendi

199 However, while eukaryotic MCM2-7 is a heterocomplex made of different polypeptide chains, the

200 Formation of the heterocomplex may also represent the first step toward r

201 ce that the TPR proteins in steroid receptor heterocomplexes may be required for signaling in vivo.

202 Formation of TNF receptor heterocomplexes may therefore 1) define a novel molecula

203 type I/type II receptor (TbetaR-I.TbetaR-II) heterocomplex-mediated signaling.

204 to the plasma membrane (PM); PM-bound HET-C heterocomplexes occurred in all three het-c incompatible

205 aranodal junctions comprised of the neuronal heterocomplex of contactin and contactin-associated prot

206 hen the fusion protein was phosphorylated, a heterocomplex of potential sorting proteins was recovere

207 effects are due to the formation of a stable heterocomplex of the dominant-negative receptor with the

208 f its biological effects by interaction with heterocomplexes of nuclear retinoic acid receptors (RARs

209 lex assembly system is to stabilize GR.hsp90 heterocomplexes once they are formed and it does not app

210 hat dissociation of GR/heat shock protein 90 heterocomplex or decrease in GR protein would account fo

211 ng conformation, but to form stable GR.hsp90 heterocomplexes, p23 must also be present in the incubat

212 oadsorbed from L cell cytosol or to GR.hsp90 heterocomplexes prepared with the minimal (hsp90.p60.hsp

213 plexes but not the formation of RIG-I/TRIM25 heterocomplexes, preventing the formation of RIG-I/MAVS

214 rgy transfer data show that the HMGB1-CXCL12 heterocomplex promotes different conformational rearrang

215 py, and other biophysical methods, including heterocomplex pulldown assays, far-UV CD spectroscopy, t

216 The resulting GR.hsp90 heterocomplex rapidly disassembles unless p23 is present

217 v-Raf selects predominantly hsp90.p50(cdc37) heterocomplexes, rather than hsp90.TPR protein heterocom

218 tment of HuH-7 with rapamycin to disrupt the heterocomplex reduced surface ASGPR binding activity by

219 Formation of this heterocomplex results in repression of the transcription

220 even for the best characterized human septin heterocomplex (SEPT2/SEPT6/SEPT7), the role of C-termina

221 ns, simulations of the six possible Atox1-WD heterocomplexes show that Atox1 interactions with WD4 ar

222 A Cfd1 mutation that caused a defect in heterocomplex stability supported iron binding to Nbp35

223 ociation constants for VibF subfragment pair heterocomplexes, suggest that the mere presence of C1 do

224 Mad; rather, high levels of c-Myc prevent a heterocomplex switch from growth-promoting Myc-Max to gr

225 is determined by assembly of stable GR.hsp90 heterocomplexes that are formed by a purified five-chape

226 otein kinases, such as v-Src and v-Raf, into heterocomplexes that contain hsp90 and either immunophil

227 ffect associated with special, highly stable heterocomplexes that influences phase separation in liqu

228 AK (IL-1 receptor-associated kinase) and the heterocomplex (the signaling complex) of the two recepto

229 osine phosphatase 1B (PTP1B) to a MET/VEGFR2 heterocomplex, thereby suppressing HGF-dependent MET pho

230 t the association of p23 with Hsp90-receptor heterocomplexes; these observations have led to the hypo

231 tor proteins and the oligomeric state of the heterocomplex; this regulation has important consequence

232 of their C termini and is necessary for the heterocomplex to accumulate in the nucleus.

233 that state of hsp90 stabilizes the GR.hsp90 heterocomplex to inactivation and disassembly.

234 iscovered that rMASP-1 and rMASP-3 also form heterocomplexes under these conditions.

235 G protein heterocomplex undergoes dissociation and association dur

236 The RAD51B/RAD51C heterocomplex was isolated and purified by immunoaffinit

237 ought that the bipartite architecture of the heterocomplex was not likely a general phenomenon.

238 nce of the interaction of PP5 with Hsp90-HRI heterocomplexes was examined by characterizing the effec

239 essivity factor, comprised of the A20 and D4 heterocomplex, was constructed and used for lead optimiz

240 To demonstrate the plant heterocomplex, we add purified mammalian p23, preadsorbe

241 terocomplexes, rather than hsp90.TPR protein heterocomplexes, we have examined the binding of p50(cdc

242 As expected, the nuclear heterocomplexes were functionally inactive, since DD1 is

243 protein retention experiments in which Hsp90 heterocomplexes were precipitated resulted in coprecipit

244 ty, and it does not assemble stable GR.hsp90 heterocomplexes when it is a component of a purified fiv

245 ed in reticulocyte lysate spontaneously form heterocomplexes when the translation lysates are mixed a

246 h kinase substrates produce kinase-chaperone heterocomplexes which are highly salt-resistant.

247 in the formation of salt-labile hsp90-kinase heterocomplexes which lack the p50(cdc37) cohort.

248 ed through the formation of the p16-CDK4-Sp1 heterocomplex, which binds to Sp1 consensus-binding moti

249 eceptor associated factors 2/1 (TRAF2/TRAF1) heterocomplex, which mediates the recruitment of two cel

250 and glutamatergic drugs bind the mGluR2/2AR heterocomplex, which then balances Gi- and Gq-dependent

251 HMGB1 and CXCL12 form a heterocomplex, which we characterized by nuclear magneti

252 Septins can self-assemble into heterocomplexes, which polymerize into highly organized,

253 Binding activity was attributed to pZPB-pZPC heterocomplexes, which were detected in co-incubation mi

254 but the MutL homologue AtMLH1, which forms a heterocomplex with AtMLH3, fails to localize normally.

255 ing DNA-binding specificities and can form a heterocomplex with DNA.

256 FtsH3 also forms a separate heterocomplex with FtsH1, thus explaining why FtsH3 is m

257 ptors (GR) overexpressed in Sf9 cells are in heterocomplex with hsp90 and have steroid binding activi

258 hHSF1 polypeptide is in a dynamic heterocomplex with Hsp90 and is incapable of specificall

259 Glucocorticoid receptors (GRs) must heterocomplex with hsp90 to have an open steroid binding

260 us where they exist in the same multiprotein heterocomplex with hsp90.

261 stem that assembles steroid receptors into a heterocomplex with hsp90.

262 or into a functional (i.e., steroid binding) heterocomplex with hsp90.

263 The MondoA transcription factor forms a heterocomplex with its obligate partner Mlx to regulate

264 eptor-regulated Smad, such as Smad2, forms a heterocomplex with the co-mediator Smad, Smad4.

265 R) is recovered from hormone-free cells in a heterocomplex with the molecular chaperone hsp90, which

266 growth conditions, the HSF1 monomer is in a heterocomplex with the molecular chaperone HSP90.

267 A variety of signaling proteins form heterocomplexes with and are regulated by the heat shock

268 PP5 was also present in Hsp90 heterocomplexes with another Hsp90 cohort, p50(cdc37), a

269 at TCTP contains a BH3-like domain and forms heterocomplexes with Bcl-xL.

270 ClpRs are found to form heterocomplexes with ClpP resulting in a ClpRP tetradeca

271 Finally, we assembled progesterone receptor heterocomplexes with hsp70, hsp40, Hop, p23, and wild ty

272 ein kinases (e.g. pp60(src), v-Raf) exist in heterocomplexes with hsp90 and a 50-kDa protein that is

273 trast, unliganded steroid receptors exist in heterocomplexes with hsp90 and a tetratricopeptide repea

274 The assembly of p53 or GR heterocomplexes with hsp90 and immunophilins was not aff

275 PP5, FKBP52, and CyP-40 exist in separate heterocomplexes with hsp90, and competition binding expe

276 acity of this machinery to properly assemble heterocomplexes with hsp90.

277 (e.g. pp60(src), Raf) that also form stable heterocomplexes with hsp90.

278 ganelles, forming homotypic interactions and heterocomplexes with its homolog Mfn1.

279 tive MS, we built native-like models of four heterocomplexes with known subunit structures and compar

280 has the same ability as p23 to stabilize GR heterocomplexes with mammalian hsp90, but GR heterocompl

281 members of the EGFR family are known to form heterocomplexes with one another, c-Src has also been sh

282 heterocomplexes with mammalian hsp90, but GR heterocomplexes with plant hsp90 are stabilized by p23 a

283 We found that rMAP-1 can engage in heterocomplexes with rMASP-1 and rMASP-3 in a calcium-de

284 show that STAT2 and STAT3 exist in separate heterocomplexes with STAT1, consistent with a model in w

285 osolic receptors that are in stable GR.hsp90 heterocomplexes with steroid binding activity, a strictl

286 id binding activity to approximately 600-kDa heterocomplexes with steroid binding activity.

287 calcium ion, (4) the ability to form stable heterocomplexes with the copper chaperone for SOD1 (CCS)

288 ite on hsp90 and that they exist in separate heterocomplexes with the glucocorticoid receptor (GR).

289 e type V TGF-beta receptor was found to form heterocomplexes with the type I TGF-beta receptor by imm

290 affected only formation and activity of the heterocomplex, without effect on homomers of either rece

291 plexes, CSLC4-CSLC4 and XXT2-XXT2, and three heterocomplexes, XXT2-XXT5, XXT1-XXT2, and XXT5-CSLC4.