ライフサイエンスコーパス: heterocyclic

1 of acetylenic esters or ketones to generate heterocyclic 10-membered intermediates that contain pair

2 which is not limited to specific aromatic or heterocyclic aldehydes.

3 Eudistoma sp. provided eudistidine C (1), a heterocyclic alkaloid with a novel molecular framework.

4 Novel heterocyclic alkaloids eudistidines A (1) and B (2) were

5 An efficient cycloaddition of heterocyclic alkenes with nitrile oxides generated in si

6 SNO-OCTs are eight-membered heterocyclic alkynes that have fast rates of reactivity

7 nd optimization of a novel class of nonbasic heterocyclic amide agonists of 5-HT2C.

8 The heterocyclic amine 2-amino-1-methyl-6-phenylimidazo[4,5-

9 ne (IQ), a highly mutagenic and carcinogenic heterocyclic amine found in cooked meats, were investiga

10 MCC was studied concerning the formation of heterocyclic amines (HAAs).

11 The relative part of heme iron (1% in diet), heterocyclic amines (PhIP + MeIQx, 50 + 25 mug/kg in die

12 number of preneoplastic lesions, but dietary heterocyclic amines and NOC had no effect on carcinogene

13 Heme iron, heterocyclic amines, and endogenous N-nitroso compounds

14 diverse and previously unreported series of heterocyclic and aryl substituted groups (24 examples) a

15 , and stereoselective synthesis of series of heterocyclic and spiroheterocyclic compounds was accompl

16 romatic acids as well as primary, secondary, heterocyclic, and even functionalized amines.

17 les rearrangement of five- to eight-membered heterocyclic anthranilamides.

18 , incorporation of a pyrazolo[1,5-a]pyridine heterocyclic appendage led to a series of high-affinity

19 Heterocyclic architectures offer powerful creative possi

20 PhIP is an abundant heterocyclic aromatic amine (HCA) and important dietary

21 Heterocyclic aromatic amines (HAAs) are formed in the cr

22 owed the separation and the determination of heterocyclic aromatic amines (HAAs) classified as mutage

23 omatic hydrocarbons (PAHs), aromatic amines, heterocyclic aromatic amines (HAAs), and N-nitroso compo

24 rganoleptic properties, but it is also where heterocyclic aromatic amines (HAs) are formed.

25 done and very well-done) on the formation of heterocyclic aromatic amines (HCAs) and polycyclic aroma

26 licating PhIP, one of the most mass-abundant heterocyclic aromatic amines formed in well-done cooked

27 ography for the determination of three polar heterocyclic aromatic amines from hamburger patties.

28 that promote meta-C-H arylation of anilines, heterocyclic aromatic amines, phenols, and 2-benzyl hete

29 ed in situ with 21 different carbocyclic and heterocyclic aromatic compounds.

30 The list of heterocyclic aromatics and the mass spectral library gen

31 Although the signals of these heterocyclic aromatics diminished with distance, some we

32 The same heterocyclic aromatics identified in snow, lake sediment

33 eum coke particles are a potential source of heterocyclic aromatics to the local environment, but oth

34 Relative concentrations of heterocyclic aromatics were estimated and were found to

35 from the analysis, focusing mainly on other heterocyclic aromatics.

36 Electron-deficient, electron-rich, and heterocyclic aryl bromides have been successfully cross-

37 Heterocyclic aryl iodides are also compatible with this

38 Meta-C-H arylation with heterocyclic aryl iodides as coupling partners is also r

39 rapid access to a diverse array of different heterocyclic as well as carbocyclic products.

40 rse electron demand Diels-Alder reactions of heterocyclic azadienes has been introduced.

41 ol (TFE), to activate the electron-deficient heterocyclic azadienes.

42 ductive activation of the electron-deficient heterocyclic azadienes.

43 entional peptides, (ii) chiral and nonplanar heterocyclic backbones that are less prone to the hydrop

44 cal that can engage in the C-H alkylation of heterocyclic bases and 1,4-quinones.

45 Under irradiation, heterocyclic biradicaloids 3 are shown to generate housa

46 A series of aromatic/heterocyclic bis-sulfonamides were synthesized from thre

47 be further functionalized to provide complex heterocyclic building blocks.

48 that the stable and commercially available N-heterocyclic carbene (NHC) 1,3-bis(2,6-diisopropylphenyl

49 Bis-N-heterocyclic carbene (NHC) aminopincer ligands were succ

50 mol % of a catalyst derived from a chiral N-heterocyclic carbene (NHC) and a copper chloride salt.

51 d Lewis acid-mediated radical reactions of N-heterocyclic carbene (NHC) boranes.

52 N-Heterocyclic carbene (NHC) catalysis has emerged as a po

53 mines with enals was realized using chiral N-heterocyclic carbene (NHC) catalysts.

54 Three N-heterocyclic carbene (NHC) catalyzed kinetic resolutions

55 lkali-metal-mediated metalation (AMMM) and N-heterocyclic carbene (NHC) chemistry, a novel C-N bond a

56 of the past 15 years the success story of N-heterocyclic carbene (NHC) compounds in organic, inorgan

57 An energy-based index of the ease of N-heterocyclic carbene (NHC) formation either by deprotona

58 iso-propylphenyl)phenyl) stabilized by the N-heterocyclic carbene (NHC) ImMe4 is reported.

59 ring structure, is studied with the common N-heterocyclic carbene (NHC) IPr [1,3-bis(2,6-diisopropylp

60 Here, we show that N-heterocyclic carbene (NHC) Ir(III) complexes can serve a

61 Dissymmetry at the N-heterocyclic carbene (NHC) ligand was identified as a ke

62 It is well-recognized that N-heterocyclic carbene (NHC) ligands have provided a new d

63 Organometallics with N-heterocyclic carbene (NHC) ligands have triggered major

64 , and a horizontal Be-Be axis supported by N-heterocyclic carbene (NHC) ligands.

65 for the reaction between N-aryl triazolium N-heterocyclic carbene (NHC) precatalysts and substituted

66 metrical unsaturated 2,6-diisopropylphenyl N-heterocyclic carbene (NHC) precursors with excellent sel

67 A fused pi-helical N-heterocyclic carbene (NHC) system was prepared and exami

68 o directly link the dicarbollide ion to an N-heterocyclic carbene (NHC) to form an isolable N-dicarbo

69 -Si bond-forming processes catalyzed by an N-heterocyclic carbene (NHC) were recently introduced; the

70 N-Heterocyclic carbene (NHC)-catalyzed intramolecular aldo

71 ical/computational investigations into the N-heterocyclic carbene (NHC)-catalyzed proton-transfer pol

72 unsaturated amide and ester equivalents in N-heterocyclic carbene (NHC)-catalyzed redox hetero-Diels-

73 The synthesis of N-heterocyclic carbene (NHC)-cyclic (alkyl)(amino) carbene

74 he synthesis and characterization of novel N-heterocyclic carbene (NHC)-gold(I) complexes and their b

75 We report the N-heterocyclic carbene (NHC)-induced activation of an othe

76 time, an extensive characterization of an N-heterocyclic carbene (NHC)-modified supported heterogene

77 pi-acceptor when compared with that of an N-heterocyclic carbene (NHC).

78 Ni(COD)2 (COD = 1,5-cyclooctadiene) and an N-heterocyclic carbene (NHC).

79 stituted allyl substrates, simply by using N-heterocyclic carbene as ligand, leading to branched prod

80 ted esters in the presence of alcohols and N-heterocyclic carbene catalysts, e.g., benzimidazolyliden

81 Relying on the established chemistry of N-heterocyclic carbene copper hydride (NHCCuH) complexes,

82 The reaction of 1 with N-heterocyclic carbene IMes afforded 3-(IMes)C14H7O2B(C6F5

83 combination of a rhodium pre-catalyst, an N-heterocyclic carbene ligand and an amino-pyridine co-cat

84 Addition of the N-heterocyclic carbene ligand IMes to fac,anti-(ONO(Cat))R

85 ckel(0) precatalysts bearing an unhindered N-heterocyclic carbene ligand, which was developed in opti

86 Readily accessed cobalt pre-catalysts with N-heterocyclic carbene ligands catalyze the Suzuki cross-c

87 Correction for 'Privileged chiral N-heterocyclic carbene ligands for asymmetric transition-m

88 ing (phenylpyridine or benzoquinoline) and N-heterocyclic carbene ligands possess intriguing structur

89 Herein the chemical conversion of N-heterocyclic carbene molecules attached to catalytic par

90 emically active groups in surface-anchored N-heterocyclic carbene molecules.

91 acuo according to the calculation, and the N-heterocyclic carbene quinoline-2-ylidene is not formed a

92 er ring boracyclopropanes (boriranes) with N-heterocyclic carbene substituents were prepared by a rec

93 to yield a thiazol-2-ylidene, which is an N-heterocyclic carbene that has high-affinity for and is p

94 The first isolable, photoswitchable N-heterocyclic carbene was synthesized and found to underg

95 y be facilitated by an NHC-Cu complex (NHC=N-heterocyclic carbene) and products obtained in 63-95 % y

96 l calculations via a NHC-stabilized (NHC = N-heterocyclic carbene) disilahydronium ion ("pi-bonded" i

97 on of the acyclic amido-chlorosilylene bis(N-heterocyclic carbene) Ni(0) complex [{N(Dipp)(SiMe3 )ClS

98 complex with a chiral sulfonate-containing N-heterocyclic carbene, are broadly applicable.

99 In particular, the development of N-heterocyclic carbene-based emitters and tetradentate cyc

100 s been synthesized from the combination of N-heterocyclic carbene-ligated gold(I) trimethylsilylchalc

101 pp=2,6-Pr(i)2 C6 H4 ) and two NHC ligands (N-heterocyclic carbene=:C[(Pr(i) )NC(Me)]2 ) was synthesiz

102 -->Ni(NHC)2 ] (1; Dipp=2,6-(i) Pr2 C6 H4 ; N-heterocyclic carbene=C[((i) Pr)NC(Me)]2 ) with N2 O furn

103 and 2b [RSi(O)(NHC)2]Cl stabilized by two N-heterocyclic carbenes (NHC = 1,3,4,5-tetramethylimidazol

104 N-Heterocyclic carbenes (NHC's) are known to serve as effi

105 ategy, the use of organocatalysts, such as N-heterocyclic carbenes (NHCs) and N-heterocyclic olefins

106 The success of achiral N-heterocyclic carbenes (NHCs) as stable electron-rich neu

107 termining ease of formation of (i) neutral N-heterocyclic carbenes (NHCs) by deprotonation of heteroc

108 carboquinoid and stabilized by two capping N-heterocyclic carbenes (NHCs) has been prepared.

109 rmation of organic films on gold employing N-heterocyclic carbenes (NHCs) has been previously shown t

110 ent density functional theory computations.N-heterocyclic carbenes (NHCs) have been applied as ancill

111 N-Heterocyclic carbenes (NHCs) have emerged as versatile l

112 =C=O (NHP=N-heterocyclic phosphenium) with N-heterocyclic carbenes (NHCs) leads to phosphaheteroallen

113 amounts of [M{N(SiMe3 )2 }2 ] (M=Fe, Co), N-heterocyclic carbenes (NHCs) react with primary phosphin

114 ent advancement in functionalizing gold by N-heterocyclic carbenes (NHCs), a promising alternative li

115 chemically different donor groups, and of N-heterocyclic carbenes (NHCs).

116 rene (9,10-diboraanthracene) stabilized by N-heterocyclic carbenes and its one- and two-electron oxid

117 An unforeseen original class of stable N-heterocyclic carbenes and, more generally, the potential

118 Mechanistic aspects of the N-heterocyclic carbenes catalyzed aerobic oxidation of ald

119 The trapping of a silicon(I) radical with N-heterocyclic carbenes is described.

120 A series of novel beta-carboline-based N-heterocyclic carbenes was prepared via Mannich reaction

121 ines and falls within a range dominated by N-heterocyclic carbenes.

122 and similar to that observed in classical N-heterocyclic carbenes.

123 orizontal lineAl double bond stabilized by N-heterocyclic carbenes.

124 rbon dioxide forms covalent complexes with N-heterocyclic carbenes.

125 ent Pd-catalyzed decarboxylative coupling of heterocyclic carboxylic acids with heterocyclic halides

126 the antipsychotic drug aripiprazole and the heterocyclic catecholamine surrogates present in the bet

127 etween the conventional binding sites in the heterocyclic cations in PIL and an in situ generated pol

128 will prove useful in the art and practice of heterocyclic chemistry and beneficial for the study of g

129 e one of the key exploration areas of modern heterocyclic chemistry.

130 of this remarkable chemist and his legacy to heterocyclic chemistry.

131 s were tentatively identified as nitrogenous heterocyclic compounds (e.g., 3-chloro-5-hydroxy-1H-pyrr

132 me) by analysing the non-volatile oxygenated heterocyclic compounds (OHC) by UHPLC/TOF-HRMS, multivar

133 Likewise, when trichloromethyl heterocyclic compounds contain another reactive function

134 se products were structurally similar to the heterocyclic compounds formed during chlorination, such

135 aromatic substitution reactions on different heterocyclic compounds has been examined.

136 hat the formation of halogenated nitrogenous heterocyclic compounds is reported from chloramination p

137 Indolizidines are bioactive heterocyclic compounds of great potential normally prepa

138 eterocycles during the synthesis of targeted heterocyclic compounds require the use of SF5 -functiona

139 the transformations of propargylamines into heterocyclic compounds such as pyrroles, pyridines, thia

140 efficiently transformed into a rare class of heterocyclic compounds-dibenzo[b,f][1,5]diazocines-by a

141 ccess to a variety of underexplored strained heterocyclic compounds.

142 s for the synthesis of biologically relevant heterocyclic compounds.

143 Benzothiophenes are heterocyclic constituents of important molecules relevan

144 e report herein that we further explored the heterocyclic core of these inhibitors by a fused imidazo

145 Nonetheless, simple catalytic routes to new heterocyclic cores are infrequently reported, and method

146 dergoes reductive elimination to provide the heterocyclic coupling adduct.

147 The reaction tolerates a variety of heterocyclic coupling partners, including pyridines, pyr

148 These small molecules of the heterocyclic diamidine family disrupted the interaction

149 base pairs, we recently discovered that the heterocyclic diamidine, DB2277, forms a strong monomer c

150 The heterocyclic diamidine, DB2277, specifically recognizes

151 Sulfurization of anionic N-heterocyclic dicarbene, [:C{[N(2,6-Pr(i)2C6H3)]2CHCLi}]n

152 Heterocyclic dications are receiving increasing attentio

153 tic research of unprecedented multitargeting heterocyclic ferrociphenols bearing either a succinimidy

154 s diverse trans-3,4-disubstituted carbo- and heterocyclic five-membered rings in high yields and with

155 -catalysed cross-coupling sequences to unite heterocyclic fragments.

156 t reaction is described in which an atypical heterocyclic framework (the anthranil or benzo[c]isoxazo

157 Then, the chemical reactivity of this heterocyclic framework was explored to develop straightf

158 A new fused N-heterocyclic framework, dipyrazolo-1,3,5-triazinane, was

159 arylation under mild conditions to give new heterocyclic frameworks.

160 hydride featuring a neutral (carbene-type) N-heterocyclic Ga(I) ligand.

161 donor and withdrawing groups, as well as by heterocyclic halides in good to excellent yields.

162 upling of heterocyclic carboxylic acids with heterocyclic halides to achieve the synthesis of biheter

163 from mono- and polyaromatic hydrocarbons and heterocyclic hydrocarbons, together accounting for 3.9-4

164 oxazolo[3,4-b]quinolin-3(1H)-one as "masked" heterocyclic hydroxylamines to generate Paal-Knorr inter

165 en described today which are stabilized by N-heterocyclic iminato ligands.

166 calculations and revealed the pi-donating N-heterocyclic imino (NHI) and sigma-donating silyl groups

167 The imidazolin-2-imino group is an N-heterocyclic imino functionality that derives from the c

168 underscore the value of harnessing strained heterocyclic intermediates as a unique approach to build

169 ng the cycloaddition reactivity of these new heterocyclic intermediates.

170 genation of diverse aliphatic, aromatic, and heterocyclic ketones as well as aldehydes, which are rea

171 Porphyrins are organic heterocyclic macrocycles with photophysical properties w

172 lts to give neutral NHCs or deprotonation of heterocyclic mesomeric betaines to give anionic NHCs is

173 ts and (ii) anionic NHCs by deprotonation of heterocyclic mesomeric betaines.

174 , such as pterins, folates, and flavins, are heterocyclic metabolites that often serve as redox-activ

175 ion of compounds containing a broad range of heterocyclic moieties.

176 ade; and (iv) the tether forms an additional heterocyclic moiety, imidazolidine-4,5-dione, a known ph

177 imple system for the construction of complex heterocyclic molecules, such as fused azoles derivatives

178 rect regioselective arylamination of various heterocyclic N-oxides was achieved successfully under re

179 e involves the initial reaction of activated heterocyclic N-oxides with DABCO, followed by in situ tr

180 tended, polycyclic heteroaromatic molecules (heterocyclic nanographenes) are a highly versatile class

181 expected thionated NDI derivatives 2-6, new heterocyclic naphtho-p-quinodimethane compounds 7 depict

182 Commercial application of many promising heterocyclic natural products is limited by their natura

183 y of bacterial alkaloids is a diverse set of heterocyclic natural products that have likely been know

184 y, 3,3'-diindolylmethane was identified as a heterocyclic, nonlipid-like GPR84 agonist.

185 thiophen-2-one is a rare example of a stable heterocyclic o-quinone methide analogue that shows a var

186 triamides [M(N'')3 ] were treated with the N-heterocyclic olefin H2 C=C(NMeCH)2 , which constitutes a

187 s a broad range of aryl, styrene, vinyl, and heterocyclic olefinic targets.

188 such as N-heterocyclic carbenes (NHCs) and N-heterocyclic olefins (NHOs) as well as phosphazene bases

189 Aromatic heterocyclic oxides, such as dibenzothiophene S-oxide (D

190 s), oxygenated-PAHs, and nitrogen containing heterocyclic PACs.

191 Hs (unsubstituted, oxygenated, nitrated, and heterocyclic PAHs).

192 on of phosphanyl ketenes, (NHP)-P=C=O (NHP=N-heterocyclic phosphenium) with N-heterocyclic carbenes (

193 e synthesis of vinyldiazaphosphonates from N-heterocyclic phosphine (NHP) and allenes via phospha-Mic

194 ng either cycloalkylphosphine derivatives or heterocyclic phosphine derivatives.

195 A novel 1,3,2-diazaphospholidine (N-heterocyclic phosphine)-thiourea-mediated phospha-Mannic

196 form C-N bonds through the utilization of N-heterocyclic phosphine-butane (NHP-butane) has been deve

197 he critical role of thiourea moiety of the N-heterocyclic phosphine-thiourea in the sequential intram

198 essible from (hetero)aryl glyoxylic acids or heterocyclic pi-nucleophiles by consecutive four- and fi

199 Azaarenes are N-heterocyclic polyaromatic pollutants that co-occur with

200 isking approach toward the radiosynthesis of heterocyclic positron emission tomography (PET) radiolig

201 provide the corresponding tricyclic bridged heterocyclic product and gave only a bis-allyl adduct, w

202 The five-membered heterocyclic products are generated in good to excellent

203 rovide the corresponding nitrogen-containing heterocyclic products in good to excellent yields.

204 Interestingly, some of these N-heterocyclic products possess the tricyclic core of epim

205 specifically dideuterated tricyclic bridged heterocyclic products, and from computational studies.

206 The discovery of novel 4-hydroxy-2-(heterocyclic)pyrimidine-5-carboxamide inhibitors of hypo

207 Heterocyclic pyrrole molecules are in situ aligned and p

208 are the first metallacycles bearing nitrogen heterocyclic radicals as bridges.

209 Compound 13 and analogues containing heterocyclic replacements for the C2 phenyl and modified

210 ansformation of diarylethenes with different heterocyclic residues permits synthesis of naphthalenes

211 le methylene unit between the oxadiazole and heterocyclic ring afforded a SphK1-selective inhibitor i

212 of diarylethenes comprising a five-membered heterocyclic ring and phenyl moiety is described.

213 The structure of the heterocyclic ring system was confirmed through single-cr

214 to date, provide direct access to diverse N-heterocyclic ring systems.

215 varying substituents at each position on the heterocyclic ring was determined; particularly, the tran

216 A single nitrogen-rich heterocyclic ring with many energetic groups is expected

217 gave thiohydantoins racemized at C-5 of the heterocyclic ring.

218 n addition to allowing the generation of two heterocyclic rings and four C-N bonds in a single operat

219 In sapphyrins, the five pyrrole/heterocyclic rings are connected through four meso-carbo

220 d, whereas in smaragdyrins, the five pyrrole/heterocyclic rings are connected through three meso-carb

221 values of the covalently fused five-membered heterocyclic rings are more negative than the five-membe

222 ngs are more negative than the five-membered heterocyclic rings formed by intramolecular coordination

223 expanded porphyrins containing five pyrrole/heterocyclic rings such as sapphyrins and smaragdyrins.

224 Several examples of bis-heterocyclic rings were also synthesized through the pro

225 es (ACPs) to afford five-membered carbo- and heterocyclic rings with concomitant intramolecular thioe

226 , as well as hydroxylation of photo-oxidized heterocyclic rings, have been identified during photodeg

227 cles contain 22pi electrons and five pyrrole/heterocyclic rings, they are structurally different.

228 id pimelate moiety and assembly of the fused heterocyclic rings.

229 rocyclic carbenes (NHCs) by deprotonation of heterocyclic salts and (ii) anionic NHCs by deprotonatio

230 its structure, the 5-membered chiral biaryl heterocyclic scaffold represents a departure from 6-memb

231 alpha is remarkably sensitive to the type of heterocyclic scaffold with oxazolo-4N-pyridines as the m

232 osition of both imidazolinium cations on the heterocyclic scaffold.

233 olidone-ring annulated thiophene/furan-based heterocyclic scaffolds (e.g., 4,5-dihydro-6H-thieno[2,3-

234 The prepared heterocyclic scaffolds are decorated with several substi

235 g of these intermediates affords an array of heterocyclic scaffolds by the formation of one or more n

236 e incorporation of an alkyne linker in other heterocyclic scaffolds can also achieve potent inhibitio

237 Furthermore, other similar heterocyclic scaffolds can also be functionalized regios

238 , provide straightforward access to bicyclic heterocyclic scaffolds containing bridgehead nitrogen ce

239 nds have found significant applications as N-heterocyclic scaffolds in self-assembly processes, in pa

240 Heterocyclic scaffolds that are either hard to synthesiz

241 ross-dehydrogenative coupling of biorelevant heterocyclic scaffolds with arylmethanes for aroylation

242 d with a wide array of medicinally important heterocyclic scaffolds with diverse functional group tol

243 orininones (carbonyl-containing, boron-based heterocyclic scaffolds) using simple reagents and condit

244 A concise synthetic methodology for new heterocyclic scaffolds, such as pyrazolo-pyrrolo-pyrazin

245 teroarylated phenol moieties by wide-ranging heterocyclic scaffolds.

246 lkenes to provide stereochemically complex N-heterocyclic scaffolds.

247 mployed in strategies for developing diverse heterocyclic scaffolds.

248 efin-based Minisci reaction to functionalize heterocyclic scaffolds.

249 the Ess-Kurti-Falck aziridination, while the heterocyclic side chains were introduced via stereoselec

250 The first single-component N-heterocyclic silylene borane 1 (LSi-R-BMes2 ; L=PhC(N(t)

251 The first chelating bis(N-heterocyclic silylene)xanthene ligand [Si(II)(Xant)Si(II

252 donating to withdrawing moieties at both the heterocyclic site and through meso-substitution of penta

253 r triazole-NHC control to give unknown fused heterocyclic skeletons, pyrrolo[3,2-c][1,2,4]triazolo[5,

254 zine-5-carboxylates, including unprecedented heterocyclic skeletons, was performed by the transformat

255 1H-imidazo[2,1-a]pyrrolo[3,4-c]isoquinoline heterocyclic skeletons, which were further transformed i

256 synthase kinase (GSK)3 inhibitor, VP3.15, a heterocyclic small molecule with good pharmacokinetic pr

257 f a chemical library, we identified a set of heterocyclic small molecules as potential inhibitors of

258 e synthesis of a wide variety of acyclic and heterocyclic small molecules.

259 The method can be used to couple two heterocyclic species so the highly enantioenriched produ

260 A series of new heterocyclic strained cyclooctynes containing a sulfamat

261 Various heterocyclic structures containing the pyrrole moiety ha

262 -O and C-N bond-cleaving to afford prevalent heterocyclic structures of N-substituted pyridones and 2

263 the preparation of a diverse array of novel heterocyclic structures.

264 iastereoselective installation of carbo- and heterocyclic substituents at position 1', orthogonal fun

265 rylisoxazoles, bearing unsaturated carbo and heterocyclic substituents at the position 4, gives the c

266 , bifunctional nitrile template that binds a heterocyclic substrate via a reversible coordination ins

267 Amination and alkynylation of heterocyclic substrates including indole, indoline, and

268 t either nitrogen or sulfur atoms present in heterocyclic substrates may bind preferentially to a tra

269 te remote, site-selective C-H olefination of heterocyclic substrates that do not have the necessary f

270 pecially for electron-deficient aromatic and heterocyclic substrates.

271 ctive and can couple synthetically important heterocyclic substrates.

272 was employed in a convergent assembly of the heterocyclic subunits.

273 A series of acidic diaryl ether heterocyclic sulfonamides that are potent and subtype se

274 ts which have been explored as precursors in heterocyclic synthesis.

275 ives as the first representatives of a novel heterocyclic system.

276 n withdrawing/donating aroyl units including heterocyclic systems are well tolerated in the present d

277 t to broader conformational issues involving heterocyclic systems bearing aryl substituents.

278 Novel tricyclic bridged heterocyclic systems can be readily prepared from sequen

279 xity by domino/tandem process to produce the heterocyclic systems in good yields.

280 The assembly of both heterocyclic systems is initiated by an aza-Michael reac

281 ic species, in particular, a wide variety of heterocyclic systems spanning small 3-membered ring syst

282 gy has been established for the synthesis of heterocyclic systems under mild conditions.

283 is, recent, distinct approaches to construct heterocyclic systems using oxetanes are described.

284 azoles, 2H-benzotriazoles, and related fused heterocyclic systems with good functional group compatib

285 Such heterocyclic systems would be expected to be useful scaf

286 d [3,4-a]isoquinolines, as well two more new heterocyclic systems, pyrrolo[3,4-c][1,2,4]triazolo[5,1-

287 a valuable method for the formation of fused heterocyclic systems.

288 aborininones with the analogous carbon-based heterocyclic systems.

289 ent is followed by fragmentation to give the heterocyclic target.

290 imidazoheterocycles with a diverse range of heterocyclic thiols and heterocyclic thiones.

291 nylation of enaminones with a broad range of heterocyclic thiols and thiones using cross dehydrogenat

292 The direct amination reaction of heterocyclic thiols has been developed in the presence o

293 egy employs the reaction of easily available heterocyclic thiols or thiones with imidazoheterocycles.

294 inazoline derivatives from the corresponding heterocyclic thiols with amines in good to excellent yie

295 h a diverse range of heterocyclic thiols and heterocyclic thiones.

296 mising classes of iron chelators are alpha-N-heterocyclic thiosemicarbazones with Triapine as the mos

297 pyrroles fused with two peripheral arenes or heterocyclic units has been realized through the concise

298 A variety of heterocyclic units, including pyrazoles, benzopyrazoles,

299 r the assembly of compounds bearing multiple heterocyclic units.

300 ubstituents are tolerated as well as various heterocyclic units.