ライフサイエンスコーパス: heterodimeric

1 SFTI-1 (sunflower trypsin inhibitor-1) and a heterodimeric 2S albumin.

2 TmrAB is a heterodimeric ABC exporter from the thermophilic Gram-ne

3 Here, we present the apo structure of the heterodimeric ABC exporter TM287/288 and compare it to t

4 DEER measurements on the heterodimeric ABC exporter TM287/288 from Thermotoga mar

5 In particular, heterodimeric ABC exporters exhibit pronounced allosteri

6 rovide detailed mechanistic insight into how heterodimeric ABC exporters operate.

7 d with antigen processing (TAP) is a 150 kDa heterodimeric ABC transport complex that selects peptide

8 Here we report that, for the heterodimeric ABC transporter TmrAB, the extent of delip

9 aneic acids A and B are formally dimeric and heterodimeric adducts of yunnaneic acids C and D.

10 Integrins are a family of heterodimeric adhesion receptors that transmit signals b

11 le linker was removed, yielding fully mature heterodimeric albumin.

12 Imidazole-3-glycerol phosphate synthase is a heterodimeric allosteric enzyme that catalyzes consecuti

13 Integrins are heterodimeric alpha/beta extracellular matrix adhesion r

14 Integrins are a family of heterodimeric (alpha+beta) adhesion receptors that play

15 Integrins are heterodimeric (alphabeta) cell surface receptors that ar

16 CD98hc (SLC3A2), a heterodimeric amino acid transporter, modulates integrin

17 7R)- and (2S,7S)-2 and a series of homo- and heterodimeric analogues in which octanedioic acid was us

18 ution cryo-EM data is superior in predicting heterodimeric and heterotrimeric protein assemblies.

19 e sought crystal structures of aglycosylated heterodimeric and homodimeric "knob" and "hole" Fc fragm

20 r structural and functional differences, the heterodimeric and homodimeric kinesin-14s share a common

21 The design comprises two, noncovalent, heterodimeric and homotrimeric coiled-coil bundles.

22 nsing, it is unknown why the Rag GTPases are heterodimeric and whether their subunits communicate wit

23 hat Sid2p and Mob1p both exist as monomeric, heterodimeric, and homodimeric species throughout the ce

24 e describe the identification of a series of heterodimeric antagonists with highly potent antiprolife

25 e function of these dimers, specifically the heterodimeric AP-1 comprised of JunD and c-Fos (AP-1(Jun

26 DNA dissociation rates of wild-type AraC and heterodimeric AraC constructs in which one subunit is ca

27 The structure reveals the heterodimeric architecture of the complex and donor subs

28 , a potential drug target, is unique for its heterodimeric arrangement and an active site different f

29 Although recent studies have suggested heterodimeric assembly of mGlu receptors in vitro, the d

30 signaling can be silenced through a physical heterodimeric association with CB2, thereby inhibiting s

31 binding and transcriptional activity through heterodimeric association with several members of the nu

32 The carotenoid is required for the heterodimeric association, assembling an orange complex

33 Cohesin contains a heterodimeric ATP-binding Cassette (ABC) ATPase comprise

34 GUVs incorporating BmrC/BmrD, a bacterial heterodimeric ATP-binding cassette efflux transporter, w

35 intenance of chromosomes 1 and 3 (Smc1-Smc3) heterodimeric ATPase, the kleisin subunit sister chromat

36 of proteins that bind the TIRs identified a heterodimeric basic leucine zipper (bZIP) complex betwee

37 odies expressed in the same cell to generate heterodimeric bispecific antibodies.

38 e developed a novel one-arm single chain Fab heterodimeric bispecific IgG (OAscFab-IgG) antibody form

39 Each of these actin structures relies on heterodimeric capping protein (CAPZ), which blocks actin

40 xperimental system to modulate the levels of heterodimeric capping protein (CP) and examine the conse

41 Heterodimeric capping protein (CP) is a conserved and ub

42 or data alignment and analysis, we show that heterodimeric capping protein can replace Aip1p, but Aip

43 r genetic studies reveal that the ubiquitous heterodimeric capping protein transduces ROS signaling t

44 Moreover, Twf2a binds heterodimeric capping proteins, but the role of this int

45 e Sox pathway are covalently attached to the heterodimeric carrier protein SoxYZ through conjugation

46 n silico studies to identify the most likely heterodimeric CCL5-HNP1 complex which was subsequently u

47 They share the heterodimeric CD122/CD132 receptor to deliver their sign

48 ic CEACAM6 complex, monomeric CEACAM8, and a heterodimeric CEACAM6-CEACAM8 complex.

49 Integrins are heterodimeric cell surface adhesion and signaling recept

50 Integrins are abundant heterodimeric cell-surface adhesion receptors essential

51 These screens reveal the heterodimeric, circadian rhythm TFs Clock and Bmal1 as g

52 the IntS11/9 and, by analogy, the CPSF73/100 heterodimeric cleavage factors distinguish themselves fr

53 GPS cleavage generates not only the heterodimeric cleaved full-length Pc1 (Pc1(cFL)) in whic

54 ase catalytic subunit E9 associated with its heterodimeric co-factor A20.D4 required for processive g

55 e that CDC48A physically associates with its heterodimeric cofactor UFD1-NPL4, known to bind ubiquiti

56 e KEAP1-CUL3 E3 complex, with the aid of the heterodimeric cofactor UFD1/NPL4 and the UBA-UBX-contain

57 designed a heterotrimer from three pairs of heterodimeric coiled coils that mediate specific interac

58 We have substituted an antiparallel heterodimeric coiled-coil motif for the beta-strand stal

59 lex with Geminin showed a tight head-to-head heterodimeric coiled-coil.

60 he retromer-linked SNX-BAR proteins comprise heterodimeric combinations of SNX1 or SNX2 with SNX5 or

61 Here we present the crystal structures of a heterodimeric complex between the extracellular domains

62 studied to date by forming an anti-parallel heterodimeric complex between two peptides that are larg

63 The N-terminal acetyltransferase NatA is a heterodimeric complex consisting of a catalytic subunit

64 sary to load hSOD1 with Cu(I), requiring the heterodimeric complex formation with hSOD1 fostered by t

65 t 2.8-A-resolution crystal structures of the heterodimeric complex formed between the ligand-binding

66 nase-like orphan receptor 2 (ROR2) to form a heterodimeric complex in mammalian cells.

67 These findings imply that such heterodimeric complex is the functional unit in mitochon

68 We determine that the heterodimeric complex of methyltransferase domains, comb

69 (ABCG8), two half-transporters that act as a heterodimeric complex promoting sterol secretion.

70 G9a and GLP lysine methyltransferases form a heterodimeric complex that is responsible for the majori

71 le integrin beta2 is primarily released as a heterodimeric complex with alphaM that retains its abili

72 e absence of the FliF(C) peptide but forms a heterodimeric complex with the peptide, and we show that

73 In the cell, Timeless forms a constitutive heterodimeric complex with Tipin.

74 confirm the previously identified Pf12-Pf41 heterodimeric complex, and analysis of individual cross-

75 th the N-terminal domain of DnaA revealing a heterodimeric complex.

76 te editing at almost all sites, suggesting a heterodimeric complex.

77 itin phosphorylation by wild-type PINK1 in a heterodimeric complex.

78 that avian and mammalian TAP1 and TAP2 form heterodimeric complexes across taxa.

79 rted, and here we show that AT1R and FP form heterodimeric complexes in both HEK 293 and vascular smo

80 I domain used in TALENs to generate obligate heterodimeric complexes substantially and significantly

81 d of MCL1, but not that of BAK, forms stable heterodimeric complexes with cBID in a manner adjustable

82 e to homodimerize, it is more likely to form heterodimeric complexes with PAK1.

83 members c-Jun, JunB, and JunD, which formed heterodimeric complexes with the AP-1 family members act

84 ze and provides evidence that Cullin 5 forms heterodimeric complexes with the Cullin 4a-DDB1 complex.

85 e show that in Drosophila melanogaster, both heterodimeric components of the SUMO E1-activating enzym

86 dynamic TCR quaternary change involving its heterodimeric components.

87 We demonstrate that a single heterodimeric core-TAP complex is active in peptide bind

88 ase CnsC from Penicillium that catalyzes the heterodimeric coupling between two different indole moie

89 This heterodimeric cpSRP recognizes LHCP and delivers it to t

90 t/sGCbetacat model derived from the inactive heterodimeric crystal structure of the catalytic domains

91 lored with a focus on Drosophila bursicon, a heterodimeric cystine-knot protein that activates the G

92 netically engineered a novel IL27p28/IL12p40 heterodimeric cytokine (p28/p40) that antagonizes signal

93 Interleukin 35 (IL-35) is a heterodimeric cytokine composed of IL-12p35 and Ebi3 sub

94 IL-12 is a 70-kDa heterodimeric cytokine composed of the p35 and p40 subun

95 IL-27 is a heterodimeric cytokine composed of the subunits p28 and

96 eceptor, a G-protein-coupled receptor, and a heterodimeric cytokine receptor in living cells with exc

97 These tyrosine kinases associate with heterodimeric cytokine receptors such as IL-7 receptor o

98 ization of gp130, a common component of many heterodimeric cytokine receptors.

99 Creation of the biologically active p28/p40 heterodimeric cytokine represents an important proof-of-

100 in 35 (IL-35) belongs to the IL-12 family of heterodimeric cytokines but has a distinct functional pr

101 the p35 and p19 polypeptides to generate the heterodimeric cytokines IL-12 and IL-23, respectively.

102 Interleukin (IL) 12 and IL23 are two related heterodimeric cytokines produced by antigen-presenting c

103 in stonefish venom is stonustoxin (SNTX), a heterodimeric cytolytic protein that induces cardiovascu

104 d, formation of these potentially protective heterodimeric disulfide complexes is limited, and so cel

105 did permit DNA binding by a tissue-specific heterodimeric DNA-binding partner, myogenic differentiat

106 are exchanged in part or fully to design new heterodimeric domains.

107 Lys63-linked polyUb chains, catalyzed by the heterodimeric E2 enzyme Ube2N/Ube2V2.

108 The monoUb is a substrate for the heterodimeric E2 Ube2N/Ube2V2, resulting in TRIM21-ancho

109 the other operating with the E2 Ubc4 and the heterodimeric E3 Slx5/Slx8.

110 the first cloning of the EcR subunit of the heterodimeric EcR-USP ecdysone receptor.

111 1 or Arg1914 binding determinants delocalize heterodimeric envoplakin from intracellular vimentin and

112 e palmitoyltransferase is a highly conserved heterodimeric enzyme complex.

113 decarboxylated by sirohaem decarboxylase, a heterodimeric enzyme composed of AhbA and AhbB, to give

114 The recombinant heterodimeric enzyme has the expected activities in its

115 HIV-1 reverse transcriptase (RT) is a heterodimeric enzyme that converts the genomic viral RNA

116 alyses confirmed the renal expression of the heterodimeric EPO receptor/CD131 complex, which is requi

117 NA binding assays also show that, within the heterodimeric ERCC1-XPF complex, XPF specifically recogn

118 Integrins are heterodimeric extracellular matrix receptors that are es

119 Ms) of RIP1 and RIP3 mediate the assembly of heterodimeric filamentous structures.

120 be the crystal structure of human primase in heterodimeric form consisting of full-length catalytic s

121 rmore, our data show that in higher plants a heterodimeric form of cpSRP is required for the formatio

122 trast between the functions of the homo- and heterodimeric forms of proteins deserves the attention o

123 A that detects both the single-chain and the heterodimeric forms of the cytokine.

124 a wealth of information concerning monomeric/heterodimeric forms of this kinase.

125 terestingly, the role of ABCD2 (in homo- and heterodimeric forms) in the metabolism of polyunsaturate

126 aration, a molecular feature differentiating heterodimeric from homodimeric ABC exporters.

127 GABAB receptors are heterodimeric G protein-coupled receptors, which control

128 ric acid type B (GABAB) receptors, which are heterodimeric G-protein-coupled receptors constructed fr

129 GABABRs are heterodimeric G-protein-coupled receptors that are compo

130 The heterodimeric gH/gL complex binds to the EBV epithelial

131 we show the first crystal structures of the heterodimeric GluN1-GluN2A ATD, which provide the comple

132 rum and other apicomplexans possess a unique heterodimeric glutamyl-tRNA amidotransferase consisting

133 The HSV heterodimeric glycoprotein gE/gI is important for antero

134 mulating hormone and luteinizing hormone are heterodimeric glycoproteins expressed in gonadotropes.

135 In heterodimeric GPPSs, a non-catalytic small subunit (GPPS

136 findings indicate that the expression of the heterodimeric gut homing integrin alpha4beta7 can influe

137 er understand CCC protein recruitment by the heterodimeric HIF transcription factor, we used x-ray cr

138 ysis and electron microscopy reveal that the heterodimeric Hop2-Mnd1 is a V-shaped molecule.

139 beta subunit proteins and, consequently, the heterodimeric hormone secretion.

140 ew strategy for making monovalent bispecific heterodimeric IgG antibodies in mammalian cells.

141 In addition, the bispecific heterodimeric IgG derived from anti-HER2 and anti-EGF re

142 The engineered heterodimeric IgG molecules maintain the overall IgG str

143 t could be embedded in monovalent bispecific heterodimeric IgG to make best-in-class therapeutic anti

144 We produced heterodimeric IgGs from transiently and stably transfect

145 nd Calu-3 human tumor models showed that the heterodimeric IgGs strongly inhibited tumor growth.

146 27p28 establish efficacy of single chain and heterodimeric IL-12 family cytokines in treatment of a C

147 thus allows secretion of biologically active heterodimeric IL-12.

148 " mechanism of action for IL-15:IL-15Ralpha (heterodimeric IL-15 or hetIL-15) where the manner by whi

149 These identified properties of heterodimeric IL-15 provide a strong rationale for the e

150 ent homodimeric cytokines (IL-17A-F) and the heterodimeric IL-17A/F.

151 The cytokine IL-17, and signaling via its heterodimeric IL-17RA/IL-17RC receptor, is critical for

152 We found that both subunits of the heterodimeric IL-18 receptor are highly expressed in the

153 However, Th17 establishment also requires heterodimeric IL-23, but the mechanisms that regulate IL

154 The effects of heterodimeric IL-27 (p28/EBI3) have been implicated in t

155 Heterodimeric IL-27 (p28/EBV-induced gene 3) is an impor

156 es Th2 immune responses through binding to a heterodimeric IL-33Ralpha (ST2L)/IL-1alpha accessory pro

157 Expression of the heterodimeric IL-35 cytokine was targeted to beta-cells

158 on agonist-induced inside-out activation of heterodimeric integrin receptors by a mechanism involvin

159 t selectively binds the beta7 subunit of the heterodimeric integrins alpha4beta7 and alphaEbeta7.

160 ell surface expression of TIM-3 by forming a heterodimeric interaction in cis through the highly rela

161 ves from each other and demonstrate that the heterodimeric interaction is functionally required for s

162 -like domain or, in the full-length protein, heterodimeric interactions with a maturation protein.

163 ts choice of dimerization partner, promoting heterodimeric interactions with E47 (Tcfe2a), as opposed

164 An enormous heterodimeric interface appears to be responsible for an

165 nied by rearrangement of the GluN1-GluN2 ATD heterodimeric interface, altering subunit orientation in

166 [2Fe-2S](2+) GRX5 donate their cluster to a heterodimeric ISCA1/ISCA2 complex.

167 ugh structural determination of a C-terminal heterodimeric Kar3Vik1, electron microscopy, equilibrium

168 The properties of KIF3CC were not shared by heterodimeric KIF3AC and required the unique KIF3C-speci

169 The beta2 integrins (CD11/CD18) are heterodimeric leukocyte adhesion molecules expressed on

170 sary and sufficient for generation of stable heterodimeric ligands with enhanced activity and can ena

171 Cohesins are deposited by a conserved heterodimeric loading complex composed of the Scc2 and S

172 nd their cleaved propeptides copurified as a heterodimeric low molecular weight complex that stimulat

173 et highly similar MTase subunits that form a heterodimeric M1M2S MTase.

174 Inhibition of the catalytic subunit of the heterodimeric methionine S-adenosyl transferase-2 (MAT2A

175 ed to form exclusive homodimers, 16 possible heterodimeric mGluRs have been proposed but their existe

176 reporting a general approach to characterize heterodimeric mGluRs, our study opens new avenues to und

177 cling of naked TAS2R14 in the absence of the heterodimeric milieu.

178 es to promote dsDNA degradation by forming a heterodimeric molecular machine.

179 sociated CD3epsilongamma and CD3epsilondelta heterodimeric molecules, which, along with CD3zetazeta h

180 s (PAS-A and PAS-B), which mediate homo- and heterodimeric mPER-mPER interactions as well as interact

181 n folds into homodimeric (mutant/mutant) and heterodimeric [mutant/wild type (WT)] myosin molecules t

182 ed AXR1 (AUXIN-RESISTANT1), a subunit of the heterodimeric NAE (E1 NEDD8-ACTIVATING ENZYME), as highl

183 Strikingly, co-depletion of NatA, a heterodimeric NAT complex that physically interacts with

184 tudy, we have taken advantage of the unusual heterodimeric nature of the Saccharomyces cerevisiae RNR

185 fy AUXIN RESISTANT1 (AXR1), a subunit of the heterodimeric NEDD8 E1 activating enzyme, as a NEDD8-mod

186 The heterodimeric NeqAB complex assumes a closed, rigid conf

187 duce neurotoxins, the genes of a specialized heterodimeric neurotoxin predate the origin of rattlesna

188 interaction partner FosB before forming the heterodimeric NFATc3-FosB transcription factor complex,

189 The heterodimeric [NiFe] hydrogenase from Desulfovibrio fruc

190 DTX1 and DTX3L, functioning as a heterodimeric Notch E3 ligase, concertedly downregulate

191 The heterodimeric nuclear factor (NF) 90/NF45 complex (NF90/

192 ing process through binding to its conserved heterodimeric nuclear receptor: Ecdysone Receptor (EcR)

193 Ralpha/farnesoid X receptor alpha (FXRalpha) heterodimeric nuclear receptors can also mediate ligand-

194 amolecular hydrogelation triggered by mixing heterodimeric nucleopeptides.

195 antibody engineering technology to develop a heterodimeric OAscFab-IgG bispecific antibody, which com

196 Mucin 1 (MUC1) is a heterodimeric oncoprotein that is aberrantly overexpress

197 hese results highlight the importance of the heterodimeric organization of P1-P2 in the human stalk p

198 , these proteins are not well conserved with heterodimeric (p48/p58) primases in eukaryotes.

199 mma, we tested the impact of p87 and p101 in heterodimeric p87-p110gamma and p101-p110gamma complexes

200 c ERK1/2 and AKT activation as well as short heterodimeric partner (SHP) mRNA induction by TCA in the

201 ration of a growth factor co-receptor with a heterodimeric partner and ligand known to regulate angio

202 uits a corepressor complex that includes its heterodimeric partner BACH1, the chromatin remodeling fa

203 uits a set of corepressors that includes its heterodimeric partner BTB and CNC homology 1, basic leuc

204 Fra-1 depletion or its heterodimeric partner c-Jun inhibits the proliferative a

205 gence of nascent HSCs in the AGM without its heterodimeric partner CBFbeta.

206 In APP/PS1 mice, Mrp14 and its heterodimeric partner Mrp8 was found to be upregulated i

207 pha-catenin, a Hippo signaling regulator and heterodimeric partner of beta-catenin at cell:cell adher

208 Here, we show that C/EBPgamma, a heterodimeric partner of C/EBPbeta whose biological func

209 IP-seq was also performed for c-Jun, a known heterodimeric partner of Meq.

210 A change in the heterodimeric partner of PPARalpha from RXRalpha to Sirt

211 mutation of the RXRA gene, which encodes the heterodimeric partner of PPARgamma.

212 integration site 1 for binding to the common heterodimeric partner Pbx1.

213 e specific binding of the VDR along with its heterodimeric partner RXR to the negative vitamin D resp

214 and induced transcriptional activity of its heterodimeric partner T-cell factor and their target gen

215 e form of the Ecdysone receptor (EcR) or its heterodimeric partner ultraspiracle (usp) causes GSC and

216 immune-regulatory functions regulated by its heterodimeric partner.

217 The AHR and heterodimeric partners AHR nuclear translocator and RELB

218 iosensor based on reversible exchange of the heterodimeric partners of green and red dimerization-dep

219 in stably transfected cells coexpressing the heterodimeric partners of SIM1 (ARNT or ARNT2).

220 Inhibin is a heterodimeric peptide hormone produced in the ovary that

221 The study of complex heterodimeric peptide ligands has been hampered by a pau

222 The heterodimeric peptide transporter consists of two homolo

223 ch the two subunits were fused into a single heterodimeric peptide, oriented as either alpha-beta or

224 Integrin alphaIIbbeta3 is a highly abundant heterodimeric platelet receptor that can transmit inform

225 rase complex consisting of the Rev1 CTD, the heterodimeric Pol zeta complex, and the Pol kappa Rev1-i

226 We demonstrate that interleukin-12, a heterodimeric pro-inflammatory cytokine consisting of th

227 secretion system, M. tuberculosis releases a heterodimeric protein complex, containing a 6-kDa early

228 Mucin 1 (MUC1) is a heterodimeric protein formed by two subunits that is abe

229 ll, Bajaj and colleagues report that CD98, a heterodimeric protein highly expressed in acute myeloid

230 coevolution provides accurate predictions of heterodimeric protein interfaces from sequence informati

231 The mucin 1 (MUC1) heterodimeric protein is aberrantly overexpressed in hum

232 ir RNA binding sites, the interfaces between heterodimeric protein molecules, the stems in RNA molecu

233 Mucin 1 (MUC1) is a heterodimeric protein that is aberrantly overexpressed i

234 sGC is a 150 kDa heterodimeric protein with two H-NOX domains (one with h

235 for an unsolved map containing a 660-residue heterodimeric protein.

236 poxia-inducible factor (HIF) 1 and HIF-2 are heterodimeric proteins composed of an oxygen-regulated H

237 gests that P. malariae expresses a family of heterodimeric proteins on its surface that have structur

238 Because TCRs function as heterodimeric proteins, we used an emulsion-based RT-PCR

239 I precomplexes occurred at normal rates, but heterodimeric PSII reaction centers (RCs) and higher ord

240 entially can be double-geranylgeranylated by heterodimeric Rab geranylgeranyltransferases (Rab-GGTs).

241 to Rad51 paralog function, we investigated a heterodimeric Rad51 paralog complex, RFS-1/RIP-1, and un

242 Here, we show that Sestrins bind to the heterodimeric RagA/B-RagC/D GTPases, and function as gua

243 hat could improve the assembly and purity of heterodimeric reaction products, we sought crystal struc

244 The symmetry of a homodimer is broken in heterodimeric reaction-center structures, such as those

245 IL-25 signals through a heterodimeric receptor (IL-25R) composed of IL-17RA and

246 I interferons (IFN-lambdas) signal through a heterodimeric receptor complex composed of the IFN-lambd

247 a1, which then recruits IL-4Ralpha to form a heterodimeric receptor complex.

248 They signal through heterodimeric receptor complexes consisting of members o

249 a T cell-derived cytokine that signals via a heterodimeric receptor composed of IL-31Ralpha and oncos

250 a pathway that is initiated by binding to a heterodimeric receptor consisting of IL-13Ralpha1 and IL

251 flammation and the locus containing IFNAR, a heterodimeric receptor for the type I interferons has be

252 ory cytokine that acts on target cells via a heterodimeric receptor formed by IL-17RA and IL-17RC sub

253 Type III IFNs signal through a unique heterodimeric receptor, IFN-lambdaR1/interleukin-10R2 (I

254 of l- and d-amino acid actions on the sweet heterodimeric receptor.

255 Integrins are a family of heterodimeric receptors that bind to components of the e

256 lved in innate immune signaling, notably the heterodimeric S100 calcium-binding proteins S100a8 and S

257 n, our results show that the expression of a heterodimeric secretory protein can be improved by harmo

258 Here, we focus on antiparallel homo- or heterodimeric small multidrug resistance proteins and ex

259 how that it interacts with h-cohesin and the heterodimeric Smc1-Smc3 complex but not with the Smc1 or

260 suggests deep functional conservation of the heterodimeric SMF1 and SCRM1 unit is required to activat

261 ation of the same [4Fe-4S](2+) cluster-bound heterodimeric species is also observed by having first o

262 a model with a subset of Cdc11p binding the heterodimeric species with a Kd < 0.1 muM when Sid2p bin

263 e unique features of this complex that drive heterodimeric specificity and high affinity binding, we

264 eby transition from a homodimeric state to a heterodimeric state in which the coiled-coil region of W

265 We found the CEACAM6-CEACAM8 heterodimeric state to be substantially favored energeti

266 pUL17 and pUL25 form a heterodimeric structure, the capsid vertex-specific comp

267 We show that PA-PB1 forms a stable heterodimeric submodule that can strongly interact with

268 by facilitating redistribution of its small heterodimeric subunit Rnr2-Rnr4 from the nucleus to the

269 T cells are defined by a heterodimeric surface receptor, the T cell receptor (TCR

270 We also tested obligate heterodimeric TALENs and found that these nucleases indu

271 y, mutations induced by both homodimeric and heterodimeric TALENs are passed efficiently through the

272 Here, the heterodimeric TAP complex was purified and reconstituted

273 to redirect the activity of T cells, normal heterodimeric TCRs or synthetic chimeric Ag receptors (C

274 re, we describe the 2.7-A X-ray structure of heterodimeric Thermus thermophilus multidrug resistance

275 ted by chronic influences of the hormones on heterodimeric thyroid hormone nuclear receptors.

276 ilt on a negative feedback loop in which the heterodimeric transcription factor circadian locomotor o

277 f extrinsic and intrinsic signals to control heterodimeric transcription factor complex formation pro

278 NX1/CBFbeta (core binding factor [CBF]) is a heterodimeric transcription factor complex that is frequ

279 Hypoxia-inducible factor 1 (HIF1) is a heterodimeric transcription factor containing an inducib

280 Hypoxia inducible factor-1 (HIF-1) is a heterodimeric transcription factor that acts as the mast

281 Hypoxia-inducible factor-1 (HIF-1) is a heterodimeric transcription factor that mediates adaptiv

282 HIF is an alpha/beta-heterodimeric transcription factor that regulates the ex

283 Hypoxia inducible factors (HIFs) are heterodimeric transcription factors induced in a variety

284 d (Runx) factors belong to a small family of heterodimeric transcription factors known to regulate li

285 Hypoxia-inducible factors (HIF) are heterodimeric transcription factors that allow cells to

286 oxia inducible factors (HIFs) are alpha/beta heterodimeric transcription factors that direct multiple

287 A key component of this mechanism is a heterodimeric transcriptional activator consisting of tw

288 P2 from the same taxon can form a functional heterodimeric translocation complex.

289 The integrins are a family of 24 heterodimeric transmembrane cell surface receptors.

290 Integrins are heterodimeric transmembrane protein receptors consisting

291 Integrins are heterodimeric transmembrane receptors consisting of alph

292 Integrins are heterodimeric, transmembrane receptors that are expresse

293 lex class I (MHC I) molecules depends on the heterodimeric transporter associated with antigen proces

294 pe (Env) spike, which consists of a compact, heterodimeric trimer of the glycoproteins gp120 and gp41

295 The heterodimeric TSC complex, consisting of Tsc1 and Tsc2 p

296 Cells producing a heterodimeric Tsr receptor containing only one functiona

297 between residues 130 and 131 and generated a heterodimeric unstable metabolite TSLP (29-130 + 131-159

298 cking VHH class (JIK-B8) were expressed as a heterodimeric VHH-based neutralizing agent (VNA2-PA).

299 Collectively, these data suggest that heterodimeric VHH-based neutralizing agents may function

300 maintaining robust editing by using obligate heterodimeric ZFNs engineered to minimize unwanted cleav