1 Two-dimensional 1H-
15N heteronuclear NMR spectra indicate that H24 is present i
2 1H and
15N heteronuclear NMR spectroscopy has allowed the direct lo
3 (1H,
15N)
heteronuclear NMR experiments aided in assigning the imi
4 Two-dimensional 1H homonuclear and 13C-
1H heteronuclear NMR spectroscopy of native tx5a isolated f
5 and heteronuclear NMR spectra and 1H-15N
3D heteronuclear NMR spectra.
6 ined using a strategy based on 2D, 3D and
4D heteronuclear NMR experiments, and on perdeuterated 13C/
7 e-dimensional (3D) and four-dimensional (
4D)
heteronuclear NMR spectroscopy.
8 ing one- and two-dimensional (1)H, (13)C
and heteronuclear NMR experiments under continuous flow.
9 is issue we establish by crystallography
and heteronuclear NMR spectroscopy that the imidazole of His
10 We used circular dichroism
and heteronuclear NMR to investigate the secondary structure
11 Using UV melting, gel electrophoresis
and heteronuclear NMR, we investigated effects of various si
12 erved HNF-3 homologous protein, Genesis,
and heteronuclear NMR, circular dichroism, DNA gel-shift ass
13 Using (1)H
and heteronuclear NMR spectroscopy, we have characterized on
14 Homo
and heteronuclear NMR spectroscopy have been used to determi
15 High-resolution homo-
and heteronuclear NMR data have been used for structure dete
16 ntent, leading to remarkably clean homo-
and heteronuclear NMR spectra of the serum metabolome that c
17 We show by homo-
and heteronuclear NMR spectroscopy that the covalent Adriamy
18 -dimensional and three-dimensional homo-
and heteronuclear NMR spectroscopy.
19 dodecylphosphocholine micelles by homo-
and heteronuclear NMR spectroscopy.
20 ins of the ribozyme, as studied by homo-
and heteronuclear NMR spectroscopy.
21 rometry (MS), tandem MS, and homonuclear
and heteronuclear NMR analyses.
22 ance restraints derived from homonuclear
and heteronuclear NMR experiments were used to calculate str
23 achieved by two-dimensional homonuclear
and heteronuclear NMR experiments, is reported for the first
24 ained using multidimensional homonuclear
and heteronuclear NMR experiments.
25 obtained from 1H and 15N 2D homonuclear
and heteronuclear NMR spectra and 1H-15N 3D heteronuclear NM
26 peaks in the amide region of homonuclear
and heteronuclear NMR spectra.
27 de has been determined using homonuclear
and heteronuclear NMR spectroscopy, and compared to the unbo
28 rmined using two-dimensional homonuclear
and heteronuclear NMR spectroscopy.
29 were completely assigned by homonuclear
and heteronuclear NMR spectroscopy.
30 ncomplexed E-domain using 2D homonuclear
and heteronuclear NMR spectroscopy.
31 ructure was determined using homonuclear
and heteronuclear NMR techniques on non-labeled and15N-label
32 gated using a combination of homonuclear
and heteronuclear NMR techniques.
33 binding site was studied by homonuclear
and heteronuclear NMR.
34 s were examined by mutagenesis, kinetic,
and heteronuclear NMR studies.
35 hia coli was investigated by mutagenesis
and heteronuclear NMR methods.
36 Previous mutagenesis
and heteronuclear NMR spectroscopy studies directed toward t
37 By deletion mutagenesis
and heteronuclear NMR spectroscopy we localised a globular d
38 near-UV CD, fluorescence, urea titration
and heteronuclear NMR experiments, we show that three amino
39 Here, using
both heteronuclear NMR and single crystal X-ray diffraction,
40 th RbfA, determined in solution at pH 5.0
by heteronuclear NMR methods.
41 ine domain of fractalkine (residues 1-76)
by heteronuclear NMR methods.
42 d-denatured state of barstar was assigned
by heteronuclear NMR experiments and structural parameters
43 residues per monomer, have been assigned
by heteronuclear NMR methods with the 15N- and 13C-labeled
44 red the autocatalytic conversion of BACE1
by heteronuclear NMR spectroscopy and used chemical shift p
45 Sxl (Sxl-RBD1 + 2) has been characterized
by heteronuclear NMR.
46 il nature of zeta(cyt) was also confirmed
by heteronuclear NMR.
47 nd the catalytic domain of FKBP38 derived
by heteronuclear NMR spectroscopy.
48 ture of the NC-SL2 complex was determined
by heteronuclear NMR methods using (15)N,(13)C-isotopically
49 ate 8.1 in these reactions was determined
by heteronuclear NMR to be a configurationally stable, alph
50 However, here we establish
by heteronuclear NMR and other spectroscopic methods that T
51 nt helix at low temperature as identified
by heteronuclear NMR relaxation measurements, secondary che
52 of the 19-residue SL2 oligoribonucleotide
by heteronuclear NMR methods.
53 flexibility in the native state as probed
by heteronuclear NMR spectroscopy and multiple conformer si
54 d the pH titration of individual residues
by heteronuclear NMR.
55 beta-chains of oxyhemoglobin, as revealed
by heteronuclear NMR spectra of chain-selectively labeled s
56 e applied differential scanning
calorimetry,
heteronuclear NMR spectroscopy, and solution small-angle
57 n D(28K) we performed detailed
complementary heteronuclear NMR and microelectrospray mass spectrometr
58 been labeled with 13C and 15N, and
complete heteronuclear NMR resonance assignments have been comple
59 or enzymatic oxidation in rat liver
cytosol;
heteronuclear NMR experiments revealed that oxidation oc
60 K(D) = 52 nM) was determined by standard 3-
D heteronuclear NMR methods.
61 the 15N nuclear spins using proton-
detected heteronuclear NMR spectroscopy.
62 plication of two, three and four-
dimensional heteronuclear NMR techniques on samples containing unifo
63 (U1A117) determined using multi-
dimensional heteronuclear NMR is presented.
64 Multi-
dimensional heteronuclear NMR spectroscopy has been used to obtain s
65 iptional repressor MBD1 by multi-
dimensional heteronuclear NMR spectroscopy.
66 9)) has been determined by multi-
dimensional heteronuclear NMR spectroscopy.
67 using two-dimensional and three-
dimensional heteronuclear NMR spectroscopy.
68 has been determined using three-
dimensional heteronuclear NMR spectroscopy.
69 has been determined using three-
dimensional heteronuclear NMR spectroscopy.
70 using two-dimensional and three-
dimensional heteronuclear NMR spectroscopy.
71 ar NMR in conjunction with three-
dimensional heteronuclear NMR.
72 n organic solvents and using two-
dimensional heteronuclear NMR in conjunction with magic-angle spinni
73 riched bile salts along with two-
dimensional heteronuclear NMR methods.
74 h as may be obtained from a two-
dimensional,
heteronuclear NMR spectrum), the inverse mode of SPARIA
75 Here, we
employ heteronuclear NMR spectroscopy to characterize a monomer
76 We have
employed heteronuclear NMR methods to determine the pK(a) values
77 effects (fluoro, nitrobenzoate), handles
for heteronuclear NMR ((19)F:fluoro; pentafluorophenyl or pe
78 he T and A bases, as previously deduced
from heteronuclear NMR measurements by Zhao et al.
79 unfolded BPTI analogue were determined
from heteronuclear NMR relaxation measurements at similar sol
80 ntains a large unfolded region identified
in heteronuclear NMR experiments.
81 Multidimensional heteronuclear NMR analysis showed that the binding mode
82 Multidimensional heteronuclear NMR and molecular modeling studies are rep
83 Multidimensional heteronuclear NMR techniques were applied to study a pro
84 A
multidimensional heteronuclear NMR study has demonstrated that a guanine-
85 Comparison of proton and
multidimensional heteronuclear NMR spectra of individual modules to those
86 structure, as determined by
multidimensional heteronuclear NMR analysis.
87 149, has been determined by
multidimensional heteronuclear NMR spectroscopy.
88 get RNA, has been solved by
multidimensional heteronuclear NMR spectroscopy.
89 eceptor, has been solved by
multidimensional heteronuclear NMR spectroscopy.
90 it of TC has been solved by
multidimensional heteronuclear NMR spectroscopy.
91 the structure was solved by
multidimensional heteronuclear NMR, revealing many structural features of
92 29-231)] is investigated by
multidimensional heteronuclear NMR.
93 of arginine was studied by
multidimensional heteronuclear NMR.
94 Dcp has been determined by
multidimensional heteronuclear NMR.
95 28)) has been determined by
multidimensional heteronuclear NMR.
96 693) has been determined by
multidimensional heteronuclear NMR.
97 estraints were derived from
multidimensional heteronuclear NMR spectra.
98 Recent developments in
multidimensional heteronuclear NMR spectroscopy and large-scale synthesis
99 omain using high resolution
multidimensional heteronuclear NMR techniques.
100 ed solubility dictated that
multidimensional heteronuclear NMR experiments had to be performed at a p
101 Phe13 in MIP-1beta, we used
multidimensional heteronuclear NMR to determine the three-dimensional str
102 ed to high resolution using
multidimensional heteronuclear NMR methods.
103 ucture of this mutant using
multidimensional heteronuclear NMR methods.
104 of the two sequences using
multidimensional heteronuclear NMR spectroscopy, and the structure was fo
105 rminal EF-hand domain using
multidimensional heteronuclear NMR.
106 modification, and two-dimensional (1)H-(15)
N heteronuclear NMR relaxation experiments.
107 Comparative two-dimensional (1)H, (15)
N heteronuclear NMR spectra indicate that the double mutan
108 ecylphosphocholine micelles using (1)H/(15)
N heteronuclear NMR spectroscopy.
109 s a function of temperature using (1)H-(15)
N heteronuclear NMR spectroscopy.
110 We used a combination
of heteronuclear NMR experiments and molecular dynamics sim
111 15N-labeled PSA, we applied a combination
of heteronuclear NMR methods, such as heteronuclear single
112 er acidic conditions, using a combination
of heteronuclear NMR, analytical ultracentrifugation, and c
113 roach is presented for the interpretation
of heteronuclear NMR spin relaxation data in mobile protein
114 of the apo-domain was determined by means
of heteronuclear NMR spectroscopy and found to be a flatten
115 P with and without bound ligands by means
of heteronuclear NMR.
116 reliable way of enhancing the sensitivity
of heteronuclear NMR in dilute mixtures of metabolites.
117 In this paper, we present a series
of heteronuclear NMR experiments for the direct observation
118 ure in solution was improved with the use
of heteronuclear NMR data.
119 An analysis
of heteronuclear-NMR-based screening data is used to derive
120 tural (13)C abundance, metabolomics based
on heteronuclear NMR is limited by sensitivity.
121 structure we report for the A form, based
on heteronuclear NMR restraints, involving a total of 1288
122 Here, using
primarily heteronuclear NMR complemented by fluorescence spectrosc
123 A high
quality heteronuclear NMR spectrum of HCV NS5B(Delta21) has been
124 ment are amenable to further high-
resolution heteronuclear NMR analysis.
125 A range of double and triple
resonance heteronuclear NMR has been used to obtain nearly complet
126 Double- and triple-
resonance heteronuclear NMR spectroscopy have been used to determi
127 Standard heteronuclear NMR methods were used to assign the protei
128 In this
study,
heteronuclear NMR methods were used to study the structu
129 These results indicate
that heteronuclear NMR, used with chain-selective isotopic la
130 ments, and illustrates the usefulness of
the heteronuclear NMR experiments.
131 ns and the first equivalent of metal
through heteronuclear NMR relaxation measurements.
132 ate was then directly demonstrated using
two heteronuclear NMR methods, an 1H-(13)C HSQC experiment a
133 rized in mutational studies, and here we
use heteronuclear NMR spectroscopy to identify the rat CD48
134 In this study, we
use heteronuclear NMR techniques to study drug binding to [m
135 We have
used heteronuclear NMR methods to probe the loop conformation
136 We have now
used heteronuclear NMR spectroscopy to determine its conforma
137 Here, we
used heteronuclear NMR spectroscopy and molecular modeling to
138 Using heteronuclear NMR (13)C-(15)N-(1)H correlation experimen
139 Using heteronuclear NMR methods we have investigated the domai
140 Using heteronuclear NMR spectroscopy, we demonstrate that a 13
141 Using heteronuclear NMR spectroscopy, we demonstrated that the
142 Using heteronuclear NMR spectroscopy, we have determined the b
143 Using heteronuclear NMR spectroscopy, we have determined the s
144 humanized anti-HER2 antibody (Hu4D5-8)
using heteronuclear NMR spectroscopy.
145 polypeptide dynamics of human FADD-DD
using heteronuclear NMR spectroscopy of (15)N and (13)C,(15)N-
146 protein unfolded in 6 M urea in detail
using heteronuclear NMR.
147 e in its free form has been determined
using heteronuclear NMR and compared to the structure of the p
148 dust mite allergen Der p 2, determined
using heteronuclear NMR methods.
149 eptide bound to BIV TAR RNA determined
using heteronuclear NMR methods.
150 (Ku86CTR(592-709)) has been determined
using heteronuclear NMR spectroscopy and dynamical simulated a
151 rtase (PC) 1 pro-domain was determined
using heteronuclear NMR spectroscopy and is the first structur
152 hydrogen isotope exchange experiments
using heteronuclear NMR spectroscopy.
153 ate kinase (PGK) has been investigated
using heteronuclear NMR spectroscopy.
154 tructure for the bound form of TAR RNA
using heteronuclear NMR.
155 cross-linked DNA fragment was studied
using heteronuclear NMR techniques.
156 Studies
using heteronuclear NMR showed a steep decrease in (1)H-(15)N
157 ed modes to be characterized in analogy
with heteronuclear NMR.