ライフサイエンスコーパス: heterotopic

1 vivo contractile function of rejecting mouse heterotopic abdominal heart allografts 5 days after tran

2 The authors developed a model of heterotopic abdominal heart transplant (HAHT) to investi

3 UN was induced in male Lewis rat hearts by heterotopic abdominal heart transplantation.

4 Heterotopic abdominal rat heart transplantation has been

5 of cardiac allograft vasculopathy (CAV) is a heterotopic (abdominal) vascularized murine cardiac tran

6 Heterotopic, abdominal transplantation of cardiac allogr

7 ne copolymerization with metallocenes having heterotopic active sites (R =Me, i-Pr) yield alternating

8 -1 protein expression is increased in murine heterotopic airway rejection, and deficiency of HO-1 acc

9 d myofibroblast infiltration was observed in heterotopic airways transplanted into the IL-13(-/-) rec

10 Recipients of heterotopic allogeneic cardiac grafts (C3H donors into B

11 ate this question, we performed vascularized heterotopic allogeneic cardiac transplants in TNF-R1-def

12 0 mug of TNFRSF25 agonist 4C12 4 days before heterotopic allogeneic heart transplantation.

13 onary IL-10 gene transfer using a functional heterotopic allograft heart transplant model in rabbits.

14 We report significant prolongation of heterotopic alpha Galactosyl transferase "knock-out" and

15 Heterotopic and control (orthotopic) transplants consist

16 antly higher than that between nonhomotopic (heterotopic and intrahemispheric) regions.

17 Using heterotopic and intravenous injection models of lung met

18 irect xenograft tumors require 2 and 5 h for heterotopic and orthotopic implantation, respectively, a

19 In vivo heterotopic and orthotopic implantations using ESRP1 ove

20 The growth of heterotopic and orthotopic Met-expressing human tumor xe

21 In mice with established heterotopic and orthotopic pancreatic tumor xenografts,

22 murine Lewis lung cancer (LLC; 3LL, H-2(b)) heterotopic and orthotopic tumor model systems in C57BL/

23 stained increase in Gd concentration in both heterotopic and orthotopic tumors using dynamic quantita

24 e-controlled NEVKP (n = 5) followed by renal heterotopic autotransplantation.

25 Heterotopic B.16-F10 melanomas elicited greater vascular

26 C57Bl/6 B7-1/B7-2-/- mice were grafted with heterotopic BALB/c hearts.

27 eir migration in the white matter, forming a heterotopic band below the normotopic cortex, and is gen

28 Qualitative analysis of heterotopic bone composition was completed with ex vivo

29 ly, conditional deletion of Zfp521 inhibited heterotopic bone formation in response to local injectio

30 Heterotopic bone formation in these animals appears to f

31 Understanding the role of burn injury on heterotopic bone formation is an important first step to

32 iation is not fully understood, we adapted a heterotopic bone formation model as a new approach for s

33 soaked beads in head explants also prevented heterotopic bone formation.

34 of stem cells to chondrocytes and subsequent heterotopic bone formation.

35 sease characterized by progressive postnatal heterotopic bone formation.

36 es aimed to prevent unwanted and detrimental heterotopic bone formation.

37 model to study the effect of burn injury on heterotopic bone formation.

38 seful in investigations of the mechanisms of heterotopic bone formation.

39 se findings suggest the residence of HSCs in heterotopic bone marrow and support the future use of th

40 tem cells), capable of generating a complete heterotopic bone organ upon in vivo transplantation were

41 Heterotopic bone volume was analyzed in vivo by micro-co

42 Subcutaneously implanted ossicles formed heterotopic bone.

43 To elucidate the role of NO in this cascade, heterotopic bronchial allografts were studied in pigs.

44 Heterotopic bronchus transplantation was performed in 33

45 Heterotopic brown Norway rat cardiac isografts were remo

46 Heterotopic Brown Norway-Lewis heart transplantations we

47 complex mismatch, as well as using a murine heterotopic cardiac allograft model (BALB/c->C57BL/6).

48 rejection, we developed a mouse vascularized heterotopic cardiac allograft model in which B6.RAG1 KO

49 graft rejection in a murine nonvascularized heterotopic cardiac allograft model.

50 Heterotopic cardiac allograft outcomes in cynomolgus mon

51 Cynomolgus monkey heterotopic cardiac allograft recipients were treated wi

52 tolerant + anti-ER-TR7 mice received BALB/c heterotopic cardiac allografts and graft survival was mo

53 ory CD4 T cells prolonged survival of murine heterotopic cardiac allografts and synergizes with conve

54 rtment, these B6 mice were transplanted with heterotopic cardiac allografts from allogeneic BALB/c do

55 ansferred into immune-deficient mice bearing heterotopic cardiac allografts from IFN-gamma receptor-d

56 Survival of Lewis to Fisher 344 rat heterotopic cardiac allografts was determined in untreat

57 mune profiles and transplanted chimeras with heterotopic cardiac allografts with or without costimula

58 the graft in cynomolgus monkey recipients of heterotopic cardiac allografts.

59 In a heterotopic cardiac allotransplantation model, CD73 defi

60 We used a murine heterotopic cardiac transplant model to identify inflamm

61 A vascularized murine heterotopic cardiac transplant model was used to test wh

62 e report the management of an infant who had heterotopic cardiac transplantation for advanced cardiom

63 shows several issues relating to the use of heterotopic cardiac transplantation in infants and the c

64 allograft rejection was investigated through heterotopic cardiac transplantation in mice.

65 The mouse heterotopic cardiac transplantation model has been used

66 A murine heterotopic cardiac transplantation model was used to te

67 We performed heterotopic cardiac transplantation using CD40-/- mice t

68 o smoke exposure in 6 groups of animals (rat heterotopic cardiac transplantation) as follows: tobacco

69 to control fibers, 10-hr heart cold storage, heterotopic cardiac transplantation, and 24-hr reperfusi

70 -mediated cardioprotection in a rat model of heterotopic cardiac transplantation.

71 At age 11 months, the patient underwent a heterotopic cardiac transplantation.

72 PVG-to-ACI rat heterotopic cardiac transplantations were performed in 4

73 ance to cardiac allografts in large animals, heterotopic cardiac transplants were performed across a

74 6) of previous transgenic CD46 pig-to-baboon heterotopic cardiac transplants were reanalyzed for base

75 Eight baboons received heterotopic cardiac xenografts from GalT-KO porcine dono

76 Heterotopic cardiac xenotransplantation from alpha1,3-ga

77 ckout cardiac xenografts after pig-to-baboon heterotopic cardiac xenotransplantation when the induced

78 ckout (GTKO) background using pig-to-primate heterotopic cardiac xenotransplantation.

79 Heterotopic cartilage develops in certain pathologic con

80 By 6 mo, heterotopic cartilage had formed in the discs and expres

81 ession of Kv4.2 (A-type) channel subunits in heterotopic cell regions of the hippocampus of MAM-expos

82 GAT-3) revealed a low level of expression in heterotopic cell regions, suggesting a reduced ability f

83 yed, rectifier (Kv2.1) potassium channels on heterotopic cells.

84 Finally, heterotopic cellular aggregates invade the Ctip2-/- stri

85 G peptide was evaluated in nude mice bearing heterotopic cervical (HT3), esophageal (OE33), pancreati

86 METHODS AND Five dogs underwent heterotopic cervical heart transplantation and simultane

87 Here we show that heterochronic and heterotopic changes early in limb development contribute

88 Previous studies have shown that heterotopic clusters of neocortically derived neurons ex

89 dynamic FC across both intrahemispheric and heterotopic connections.

90 compared with other interhemispheric (i.e., heterotopic) connections.

91 comonomers are enchained alternately at the heterotopic coordination sites of the metallocenes.

92 Heterotopic donor C57BL/6 cardiac allografts were perfor

93 However, at some sites, we also observed heterotopic effects; deactivating a specific domain in M

94 longer had any effect on them although the 'heterotopic' effects on a muscle not involved in the int

95 'Heterotopic' effects on a muscle not vibrated during the

96 g opposite effects on neighbouring muscles ('heterotopic' effects).

97 n adipocytes, which drive the early steps of heterotopic endochondral ossification by lowering oxygen

98 new members of the globin family and display heterotopic expression patterns.

99 itrate (GN) was used to induce acceptance of heterotopic FVB/N (H-2(q)) heart allografts by C57BL/6 (

100 iled studies revealed that the mechanisms of heterotopic gene expression in Plg(o) mice required fibr

101 Furthermore, by heterotopic grafting, we show that neural crest cell pop

102 Heterotopic grafts also gave rise to many ectopic muscle

103 arts were transplanted as fully vascularized heterotopic grafts from BALB/c donors into C57BL/6 recip

104 terior chamber of BALB/c eyes protects these heterotopic grafts from rejection but has only a trivial

105 Furthermore, heterotopic grafts of cells from outside the border to t

106 ouble cortex," a brain malformation in which heterotopic gray matter is interposed between zones of w

107 The commonest location of heterotopic gray matter were fronto-parietal areas of br

108 cal regions with connectivity to subcortical heterotopic gray matter.

109 fic unresponsiveness in murine recipients of heterotopic heart allografts.

110 A new rat model of heterotopic heart and lung transplantation has been deve

111 second transplant, consisting of a cervical heterotopic heart from the same ACI donor strain.

112 Heterotopic heart grafting was performed with or without

113 diated before receiving skin or vascularized heterotopic heart grafts from C57Bl/6 mice.

114 >100 day median survival of fully allogeneic heterotopic heart grafts.

115 In the murine heterotopic heart transplant model, BMS-345541 did not p

116 protocol using a rabbit functional cervical heterotopic heart transplant model.

117 assessed in a murine abdominal vascularized heterotopic heart transplant model.

118 major histocompatibility complex-mismatched heterotopic heart transplantation (BALB/c to C57BL/6) wa

119 examined in a fully allogeneic LEW to BN rat heterotopic heart transplantation (HHTx) model.

120 croRNA expression was examined in a model of heterotopic heart transplantation by microarray analyses

121 Heterotopic heart transplantation from GalT-KO pigs was

122 ngation was observed in a fully vascularized heterotopic heart transplantation model (DBA/2 into B6),

123 A rabbit functional cervical heterotopic heart transplantation model was used, and pl

124 A PVG to ACI rat heterotopic heart transplantation model was used.

125 ymosin beta4 attenuated graft rejection in a heterotopic heart transplantation model.

126 ing and reduction in LV mass were induced by heterotopic heart transplantation to the abdominal aorta

127 In vivo abdominal heterotopic heart transplantation was performed in rats

128 Heterotopic heart transplantation was performed using AC

129 ith the use of an experimental rodent model, heterotopic heart transplantation was performed, creatin

130 tion Wistar Furth [RT1u] into Lewis [RT1l]), heterotopic heart transplantation was performed, creatin

131 Orthotopic kidney and heterotopic heart transplantation were performed in diff

132 es were transferred to nude mice followed by heterotopic heart transplantation.

133 y subcutaneously to rats starting the day of heterotopic heart transplantation.

134 aive animals and from mice stimulated by rat heterotopic heart transplantation.

135 A series of 10 heterotopic heart transplants from CD46 transgenic pigs

136 lloproteinases in kidneys from recipients of heterotopic heart transplants treated with CsA for 30 an

137 Heterotopic heart transplants were performed on donor he

138 Twenty-three consecutive abdominal heterotopic heart transplants were studied.

139 Anti-Gal IgM hybridomas isolated after a rat heterotopic heart xenograft (4 days) utilized germline V

140 i-Gal hybridomas from mice 21 days after rat heterotopic heart xenografts, indicating an isotype swit

141 in glucocorticoid-treated animals following heterotopic (hepatic) expression of both carboxylated an

142 We investigated heterotopic hepatocyte transplantation on biodegradable

143 surgical techniques for orthotopic (ORT) and heterotopic (HET) hind limb transplantation.

144 n 28 NOD.rag(-/-)gammac(-/-) mice undergoing heterotopic human bronchus transplantation and reconstit

145 Orthotopic or heterotopic implantation of established cell lines requi

146 escribe our protocols for the orthotopic and heterotopic implantation of pancreatic cancer cell lines

147 The Imc conveys heterotopic inhibition to the TeO, Ipc, and SLu via wide

148 cal function regulating homotopic as well as heterotopic interhemispheric interactions (IHIs) are ass

149 Seven MGH-miniature swine received heterotopic intestinal grafts, two across MHC-matched, m

150 Mouse heterotopic isograft heart transplants were performed in

151 A heterotopic kidney engraftment site was used for compari

152 mononuclear cells or bone marrow cells and a heterotopic limb transplant were performed.

153 ex topologies are attainable with irregular, heterotopic linkers.

154 ormality in dentate granule cells, including heterotopic localization of granule cells in the molecul

155 Heterotopic lower layer replacement operations strongly

156 We performed heterotopic MHC class I/II cardiac transplants from BALB

157 yosin (CM) in Freund's adjuvant and received heterotopic, minor antigen-mismatched heart transplants.

158 Using a heterotopic model of transplantation, we investigated th

159 del (miniature swine) is feasible using this heterotopic model, and it can be useful for the study of

160 We found that in a fully mismatched heterotopic mouse heart transplantation model, T cells d

161 lopment of obliterative bronchiolitis in the heterotopic mouse trachea model.

162 be targeted to any irregularities within the heterotopic mucosa.

163 The preservation and transplantation of heterotopic murine cardiac allografts strongly induce Eg

164 We performed heterotopic murine cardiac transplants in total allogene

165 gle human leukocyte antigen (HLA)-mismatched heterotopic murine heart transplant model (HLA-A2 into H

166 To that end, heterotopic murine Lewis lung cancer and tail vein metas

167 ative airways disease (OAD) also develops in heterotopic murine tracheal allografts in association wi

168 In this study, we used an heterotopic murine tracheal transplantation model to det

169 Patch-clamp recordings from visualized heterotopic neurons indicated a lack of fast, transient

170 We conclude that heterotopic neurons lack functional A-type Kv4.2 potassi

171 Heterotopic neurons were identified in subcortical white

172 ramatic prolongation of GABAergic IPSCs onto heterotopic neurons.

173 s (or normotopic cells) but had no effect on heterotopic neurons.

174 ortex as well as a second band of misplaced (heterotopic) neurons beneath the cortex ("double cortex

175 The mice exhibited white matter heterotopic nodules and discrete cortical tuber-like les

176 urons were classified as Type I-inhibited by heterotopic noxious conditioning stimuli (HNCS) or as Ty

177 to change and therefore was more stable than heterotopic or intrahemispheric connections.

178 The many heterotopic origins represent unexpected commissural inf

179 scaffolds in nude mice gave rise to perfect heterotopic ossicles in vivo with ultrastructure of dent

180 bers and 11% to 20% of civilians who develop heterotopic ossification (HO) after blast-related extrem

181 Heterotopic ossification (HO) and fatty infiltration (FI

182 ia (POH) is a rare developmental disorder of heterotopic ossification (HO) caused by heterozygous ina

183 Pathologic extraskeletal bone formation, or heterotopic ossification (HO), occurs following mechanic

184 Heterotopic ossification (HO), or the abnormal formation

185 Heterotopic ossification (HO), the abnormal formation of

186 mine the contribution of lymphatic tissue to heterotopic ossification (HO).

187 a disabling genetic disorder of progressive heterotopic ossification (HO).

188 al admission according to risk of developing heterotopic ossification (HO).

189 cer, may possibly be repurposed for treating heterotopic ossification and other diseases caused by GN

190 udy the role of the BMP signaling pathway in heterotopic ossification and to improve our understandin

191 Heterotopic ossification consisting of mature lamellar b

192 Heterotopic ossification consists of ectopic bone format

193 essiva (FOP), a debilitating and progressive heterotopic ossification disease caused by activating mu

194 We studied the prevalence and pathology of heterotopic ossification in 347 surgically excised heart

195 Occasional reports of mild heterotopic ossification in Albright's hereditary osteod

196 ective against injury-induced and congenital heterotopic ossification in humans.

197 Lineage tracing of heterotopic ossification in mice using a Tie2-Cre constr

198 iption in cells and disrupted caALK2-induced heterotopic ossification in mice.

199 RAR-gamma agonists are potent inhibitors of heterotopic ossification in mouse models and, thus, may

200 In addition, an RAR-gamma agonist blocked heterotopic ossification in transgenic mice expressing a

201 ation of muscle architecture adjacent to the heterotopic ossification lesion, suggesting that RARgamm

202 ficans progressiva (FOP), a disease in which heterotopic ossification occurs as a result of activatin

203 ldhood, followed by disabling and widespread heterotopic ossification of skeletal muscle and deep con

204 2, which lead to inappropriate signaling and heterotopic ossification of soft tissues.

205 We also observed heterotopic ossification of the spleen and perturbation

206 Heterotopic ossification or postoperative osteolysis was

207 tients with AHO who had atypically extensive heterotopic ossification suggested a common genetic basi

208 Here we show that heterotopic ossification was essentially prevented in mi

209 cid receptor gamma (RARgamma) agonist blocks heterotopic ossification, a pathological bone formation

210 The factors contributing to heterotopic ossification, the formation of bone in abnor

211 Heterotopic ossification, the pathologic formation of ex

212 c Hedgehog signaling is sufficient to induce heterotopic ossification, whereas inhibition of this sig

213 that multiple cell sources contribute to the heterotopic ossification.

214 precluded bone union, and resulted in robust heterotopic ossification.

215 of fracture repair and substantially limited heterotopic ossification.

216 ogressiva is a rare genetic disease in which heterotopic ossifications appear in early childhood and

217 t a case of a 31-year-old woman with massive heterotopic ossifications who suffered multiple injuries

218 Associated with the heterotopic osteogenesis is an upregulation of Bmp signa

219 ibition of MSC lineage commitment may reduce heterotopic osteogenic differentiation within the injure

220 Heterotopic osteomyocutaneous flap transplantation was p

221 diation (TBI) followed by transplantation of heterotopic osteomyocutaneous flaps from hindlimbs of Au

222 ntigens by skin transplantation and received heterotopic osteomyocutaneous VCTA flaps.

223 An isolated heterotopic pancreas as a cause of bowel intussusception

224 Heterotopic pancreas is a rare developmental anomaly def

225 Though a rare entity, heterotopic pancreas should be considered in the differe

226 xamination confirmed the excised lesion as a heterotopic pancreatic tissue.

227 ograft biopsies from nonhuman primates after heterotopic partial facial segment allotransplantation f

228 velopment in immune-deficient mice receiving heterotopic porcine bronchus transplants, and major hist

229 median survival of 76 days in this group of heterotopic porcine-to-baboon cardiac xenografts represe

230 nterogradely labeled terminals, suggesting a heterotopic projection from Imc upon TeO.

231 Heterotopic projections (>1 mm beyond the main homotopic

232 Heterotopic pyramidal neurons in Lis1+/- mice were stunt

233 Here we demonstrate that heterotopic pyramidal neurons in the hippocampus fail to

234 mally positioned (normotopic) and misplaced (heterotopic) pyramidal neurons in the tish neocortex exh

235 This, and data from heterotopic quail-chick grafting studies, suggests that

236 poptosis, experiments were performed using a heterotopic rat abdominal heart transplant model and cyt

237 METHODS AND Using heterotopic rat cardiac transplantation, we tested the e

238 The heterotopic rat trachea transplant model was used.

239 evelopment, we have investigated evidence of heterotopic (relative changes in position) and heterochr

240 h deficient or sufficient for TLR4 underwent heterotopic renal allograft transplantation, with an add

241 Heterotopic renal transplantation and bilateral native n

242 Heterotopic renal transplantation was performed in 20 do

243 Heterotopic SBTx was performed from DA to Lewis rats and

244 more readily from orthotopic sites than from heterotopic sites, to identify metastasis-permissive tum

245 Heterotopic slice transplant and explant cultures sugges

246 ction in an experimental model of allogeneic heterotopic small bowel transplantation (SBTx).

247 directional graft-versus-host disease (GvHD) heterotopic small bowel transplantation was performed us

248 oth porcinized and humanized mouse models of heterotopic subcutaneous bronchus transplantation imitat

249 F/SF ligand significantly enhances growth of heterotopic subcutaneous xenografts derived from human M

250 rate that GABA-mediated synaptic function at heterotopic synapses is altered and suggests that inhibi

251 The heterotopic syngeneic murine head and neck cancer model

252 notably, there is an order of magnitude more heterotopic than homotopic projections; all cortical reg

253 ding pyramidal cell somata in normotopic and heterotopic tish neocortex.

254 g stromal or lymphoid proliferations or even heterotopic tissue.

255 cells to repopulate tumors in orthotopic and heterotopic tissues.

256 tors were upregulated during OB in the mouse heterotopic trachea model.

257 study evaluates the role of HO-1 in a murine heterotopic tracheal allograft model for obliterative br

258 Using this murine heterotopic tracheal allograft model, we evaluated the e

259 are the principal alloantigens in the mouse heterotopic tracheal model of obliterative bronchiolitis

260 ective role on chronic lung rejection in the heterotopic tracheal transplant model.

261 hrough Smad3, in the development of OB using heterotopic tracheal transplantation in wild-type and Sm

262 Using the heterotopic tracheal transplantation model, we examined

263 Using the mouse model of heterotopic tracheal transplantation, we examined the ro

264 amined using murine models of orthotopic and heterotopic tracheal transplantation.

265 literative airway disease (OAD) after murine heterotopic tracheal transplantation.

266 Murine heterotopic tracheal transplants into fully allogeneic m

267 Stuart Welch who performed a heterotopic transplant in the canine species in 1955.

268 Heterotopic transplantation in the rabbit does allow rec

269 five (R5, n=12) or nine (R9, n=12) prior to heterotopic transplantation into ACI recipients.

270 iversity of Wisconsin (UW) solution prior to heterotopic transplantation into syngeneic recipients.

271 However, after heterotopic transplantation into the hippocampus, transp

272 Using a rat (Lewis-Wistar Furth) abdominal heterotopic transplantation model, we reported previousl

273 Beta-catenin co-expression, heterotopic transplantation of CNC cells into the pharyn

274 Heterotopic transplantation of donor hearts was performe

275 By utilizing a novel EFE model of heterotopic transplantation of hearts from newborn repor

276 Heterotopic transplantation of olfactory progenitors rev

277 (I-Ad restricted) TCR-Tg CD4+ T cells after heterotopic transplantation of OVA transgene-expressing

278 Following heterotopic transplantation of rhombomeres along the ros

279 in a model of atrophic remodeling induced by heterotopic transplantation of the rat heart (duration 1

280 In a model of atrophic remodeling induced by heterotopic transplantation of the rat heart, we measure

281 loading of failing rabbit hearts by use of a heterotopic transplantation technique could lead to reco

282 ed cells repopulated tracheal scaffolds in a heterotopic transplantation xenograft model.

283 ction) or decreased (mechanical unloading by heterotopic transplantation).

284 In animal models of heterotopic transplantation, mechanical unloading of the

285 niquet placement or myocardial isolation via heterotopic transplantation.

286 tiation of these cells is also observed upon heterotopic transplantation.

287 Using heterotopic transplantations, we show that the fate of C

288 treatments need to consider the location of heterotopic transplants and administration of chemothera

289 Heterotopic transplants were performed using minor major

290 pathological retinal neovascularization and heterotopic tumor growth.

291 ing PHD3 were investigated in orthotopic and heterotopic tumor models.

292 dult tissues and in capillaries growing into heterotopic tumors expressed ADAMTS9.

293 d reduction in the spontaneous metastases of heterotopic tumors to the lungs of CXCR2(-/-) mice.

294 Valve-in-ring or heterotopic TV implantation procedures were not included

295 We performed heterotopic uterine transplants in genetically defined m

296 rized neonatal ear-heart transplantation and heterotopic vascularized heart transplantation models to

297 A rodent heterotopic working heart-lung transplantation model was

298 We have employed a rat heterotopic working-heart CR model for a magnetic resona

299 idual macrophages in vivo by MRI in a rodent heterotopic working-heart transplantation model using a

300 etry for IgG binding from sensitized cardiac heterotopic xenograft recipients.