ライフサイエンスコーパス: high endothelial venule

1 ct sites in the paracortex, particularly the high endothelial venule.

2 and with peripheral node addressin (PNAd) on high endothelial venules.

3 ritical for the formation of lymph nodes and high endothelial venules.

4 heir inability to access lymphoid tissue via high endothelial venules.

5 n vivo, and firm adhesion but not rolling on high endothelial venules.

6 ia L-selectin dependent extravasation across high endothelial venules.

7 t trafficking to lymphoid tissue by means of high endothelial venules.

8 oss a specialized microvasculature, known as high endothelial venules.

9 helial cell lines derived from rat aorta and high endothelial venules.

10 ymphatic vessels but also from blood, across high endothelial venules.

11 and lymph, entering the lymphoid tissue via high endothelial venules.

12 d on Peyer's patch and mesenteric lymph node high endothelial venules.

13 essed in the adult lymphatic endothelium and high endothelial venules.

14 ester core polysaccharide) and to lymph node high endothelial venules.

15 ng of naive T cells into lymph nodes through high endothelial venules.

16 supporting the rolling of lymphocytes along high endothelial venules.

17 ular matrix protein, HP8/HEVIN, expressed in high endothelial venules.

18 ipheral lymph node addressins on specialized high endothelial venules.

19 ent interactions with the natural ligands on high endothelial venules.

20 ymphangiogenesis, and extensive induction of high endothelial venules.

21 tive attachment of leukocytes to specialized high endothelial venules.

22 g networks of follicular dendritic cells and high endothelial venules.

23 62P, in a transient or sustained fashion, on high endothelial venules.

24 ffects on dendritic cells, stromal cells and high endothelial venules.

25 6-sulfo sialyl Lewis X L-selectin ligand in high endothelial venules.

26 arbohydrate ligand 6-sulfo sialyl Lewis X on high endothelial venules.

27 es and reduced sticking of lymphocytes along high endothelial venules.

28 ent on O-glycans of various glycoproteins in high endothelial venules.

29 er/Thr, functions as an L-selectin ligand in high endothelial venules.

30 phocytes to salivary and lacrimal glands via high endothelial venules; 3) clonal expansion of autoimm

31 ance through specialized blood vessels named high endothelial venules, a process that increases marke

32 tal life, when only MAdCAM-1 is expressed on high endothelial venules, an unusual subset of CD4 + CD3

33 21 and CCL19, but not CXCL12, are located in high endothelial venules and are, therefore, in an appro

34 Similarly, in certain lymphoid tissues, high endothelial venules and basal and subcapsular epith

35 ar tLTs, comprising B- and T-cell areas with high endothelial venules and dendritic cells.

36 The mutant CD4(+) T cells adhered poorly to high endothelial venules and exhibited defects in lymph

37 tis (RA) synovial tissue (ST), often contain high endothelial venules and follicular dendritic cells

38 a marked decrease in lymphocyte sticking to high endothelial venules and in recruitment of resident

39 mphoid organ chemokine (SLC) is expressed in high endothelial venules and in T cell zones of spleen a

40 on leukocytes mediating leukocyte rolling in high endothelial venules and inflamed microvessels.

41 the mucosal addressin MAdCAM-1 on lymph node high endothelial venules and its counterreceptor, the Pe

42 enter lymph nodes through and migrate along high endothelial venules and later disperse and integrat

43 High endothelial venules and lymphatic endothelium expre

44 hoid organs and 6Ckine has been localized to high endothelial venules and lymphatic endothelium, we p

45 impaired T-lymphocyte extravasation through high endothelial venules and reduced subsequent parenchy

46 where relatively high shear forces exist in high endothelial venules and sinusoids, respectively.

47 mphocytes and dendritic cells and containing high endothelial venules and stromal cells.

48 lidated into organized lymphoid tissue, with high endothelial venules and stromal reticulum.

49 Ac6ST-2 in L-selectin ligand biosynthesis in high endothelial venules and their importance in immune

50 ased rats was vascularized by aquaporin-1(+) high endothelial venules and vascular cell adhesion mole

51 travital imaging to show that, after exiting high-endothelial venules and before entry into lymph nod

52 pleen, the endothelial cells of capillaries, high endothelial venule, and sinusoids produced abundant

53 M-1, VCAM-1, MAdCAM-1, and PNAd) features of high endothelial venules, and ability to respond to anti

54 in their cellular content and organization, high endothelial venules, and lymphatic vessels (LVs).

55 ed exclusively on the lymphatic endothelium, high endothelial venules, and rarely on adult vascular e

56 ny cortical sinuses are situated adjacent to high endothelial venules, and some lymphocytes access th

57 e expression patterns of laminin proteins in high endothelial venule basement membranes and the corti

58 d immunity, OT-II cells arrested on DCs near high endothelial venules beginning shortly after extrava

59 VE-JAM is prominently expressed on high endothelial venules but is also present on the endo

60 cells to their ligands CD34 and CD54 on the high endothelial venule can be enhanced during inflammat

61 tic cells can migrate to lymph nodes through high endothelial venule cells, and chemokines and nonche

62 ated follicular gastritis and MALT lymphomas high endothelial venules coexpressed mucosal addressin c

63 node addressin and sialyl 6-sulfo Lewis X in high endothelial venules, considerably reduced lymphocyt

64 presence of L-selectin ligands on lymph node high endothelial venules does not affect lymphocyte homi

65 Aortic and high endothelial venule EC treated identically resulted

66 e draining lymph node includes the growth of high endothelial venule endothelial cells and is functio

67 Although high endothelial venules expressing peripheral lymph nod

68 cell compartmentalization, the formation of high endothelial venules, follicular dendritic cell netw

69 Lymphatic vessels, as well as high endothelial venules, form within these lymphoid agg

70 excessive collagen deposition, and increased high endothelial venule formation.

71 eucine-rich alpha2 glycoprotein/leucine-rich high endothelial venule glycoprotein, suppressor of cyto

72 antigen), an L-selectin ligand expressed on high endothelial venules, has been shown to require a mi

73 Hec-6st is a highly specific high endothelial venule (HEV) gene that is crucial for r

74 Secondary lymphoid-tissue chemokine (SLC), a high endothelial venule (HEV)-associated chemokine, has

75 ing and rolling of lymphocytes by binding to high endothelial venule (HEV)-expressed ligands during r

76 icular dendritic cells (DC), associated with high endothelial venules (HEV) and clusters of T cells a

77 cyte binding to lymph node and Peyer's patch high endothelial venules (HEV) and inhibits T-cell extra

78 duces adenosine from AMP and is expressed on high endothelial venules (HEV) and subsets of lymphocyte

79 High endothelial venules (HEV) are specialized plump pos

80 All NALT high endothelial venules (HEV) expressed PNAd, either as

81 tes the initial attachment of lymphocytes to high endothelial venules (HEV) in lymph nodes.

82 sed also on vascular endothelium, especially high endothelial venules (HEV) in lymphoid organs, such

83 ated sialyl Lewis(x), which are expressed on high endothelial venules (HEV) in secondary lymphoid org

84 eated cremaster muscles and in Peyer's patch high endothelial venules (HEV) of Core2GlcNAcT-I null (c

85 lomucin ligands such as CD34 and GlyCAM-1 on high endothelial venules (HEV) of lymph nodes results in

86 Lymphocyte trafficking across high endothelial venules (HEV) of peripheral lymph nodes

87 phocytes (>95% inhibition) from attaching to high endothelial venules (HEV) of Peyer's patches and ot

88 cyte adhesion to addressins expressed in the high endothelial venules (HEV) of secondary lymphoid org

89 dhesion to carbohydrate ligands expressed on high endothelial venules (HEV) of the secondary lymphoid

90 kocyte rolling and adhesion in Peyer's patch high endothelial venules (HEV) of wild-type, L-selectin-

91 merged functional blood vessels develop from high endothelial venules (HEV), in which the proliferati

92 of lymphocyte binding in vitro to lymph node high endothelial venules (HEV), specialized vessels that

93 r in chronically inflamed lymph nodes around high endothelial venules (HEV).

94 using L-selectin to bind specific ligands on high endothelial venules (HEV).

95 of T cells to secondary lymphoid organs via high endothelial venules (HEV).

96 ween circulating lymphocytes and specialized high endothelial venules (HEV).

97 sialomucin-like receptors on the surface of high endothelial venules (HEV).

98 ohydrate ligands expressed on the surface of high endothelial venules (HEV).

99 L-selectin ligands on peripheral lymph node high endothelial venules (HEV).

100 eractions with specific ligands presented on high endothelial venules (HEV).

101 endent adhesion of these cells to lymph node high endothelial venules (HEV).

102 normally initiated by L-selectin (CD62L) in high endothelial venules (HEV).

103 eviously described ligands for L-selectin on high endothelial venules (HEV).

104 f L-selectin ligands expressed by lymph node high endothelial venules (HEV).

105 igh T-cell infiltration, and the presence of high endothelial venules (HEV).

106 and donor-specific cell location relative to high endothelial venules (HEV).

107 l lymph node addressing (PNAd) and MAdCAM on high endothelial venules (HEV).

108 remain unknown, particularly with regard to high endothelial venules (HEV).

109 ral lymph node addressin (PNAd) presented on high-endothelial venule (HEV)-like vessels.

110 (LNCs) tethered and rolled in postcapillary high endothelial venules (HEVs) and to a lesser extent i

111 g lymph nodes across vascular portals termed high endothelial venules (HEVs) because of lack of expre

112 High endothelial venules (HEVs) developed that expressed

113 mentalization, antigen presenting cells, and high endothelial venules (HEVs) expressing mucosal addre

114 We show that high endothelial venules (HEVs) in BALT express substant

115 e recirculation and endothelial phenotype at high endothelial venules (HEVs) in lymph node cortex.

116 s for lymphocyte L-selectin are expressed on high endothelial venules (HEVs) in peripheral lymph node

117 ipheral lymph node addressin (PNAd)-positive high endothelial venules (HEVs) in relationship to the s

118 the tethering and rolling of lymphocytes on high endothelial venules (HEVs) in secondary lymphoid or

119 receptor, mediates rolling of lymphocytes on high endothelial venules (HEVs) in secondary lymphoid or

120 es home to peripheral lymph nodes (PLNs) via high endothelial venules (HEVs) in the subcortex and inc

121 microscopy, we find that B cell adhesion to high endothelial venules (HEVs) is disrupted when CCR7 a

122 eased binding of monocytes to perifollicular high endothelial venules (HEVs) of lymph nodes draining

123 ctin on lymphocytes with sulfated ligands on high endothelial venules (HEVs) of lymph nodes results i

124 in (PNAd), a set of sialomucins displayed on high endothelial venules (HEVs) of lymph nodes.

125 ectin initiates lymphocyte interactions with high endothelial venules (HEVs) of lymphoid organs throu

126 -selectin mediates rolling of lymphocytes in high endothelial venules (HEVs) of peripheral lymph node

127 Here, we demonstrate that high endothelial venules (HEVs) of the greater omentum c

128 How high endothelial venules (HEVs) permit lymphocyte transm

129 (ICAM-1) and CCL21 chemokine, exclusively in high endothelial venules (HEVs) that are chief portals f

130 tensively studied, little is known about how high endothelial venules (HEVs) within Peyer's patches (

131 These vessels, designated tumor high endothelial venules (HEVs), appear to facilitate tu

132 ture phenotype of peripheral lymph node (LN) high endothelial venules (HEVs), defined as MAdCAM-1(low

133 ell migration to LNs, their interaction with high endothelial venules (HEVs), specialized blood vesse

134 (CM) rolled and firmly adhered (sticking) in high endothelial venules (HEVs), whereas naive T cells w

135 not CD8(IL-2) cells, rolled and arrested in high endothelial venules (HEVs).

136 numbers of blood-borne monocytes to LNs via high endothelial venules (HEVs).

137 between lymphocytes and endothelial cells in high endothelial venules (HEVs).

138 bility to initiate rolling along specialized high endothelial venules (HEVs).

139 er, remnant LNs showed impaired formation of high endothelial venules (HEVs).

140 lymph nodes by interacting with and crossing high endothelial venules (HEVs).

141 edominately used CCR7 signaling to adhere to high endothelial venules (HEVs).

142 dent firm adhesion to the luminal surface of high endothelial venules (HEVs).

143 issues and rare cognate T cells entering via high endothelial venules (HEVs).

144 attenuated integrin-mediated firm arrest in high endothelial venules (HEVs).

145 3(-/-) mice has peripheral node addressin(+) high endothelial venules (HEVs).

146 L-selectin binding to sialomucin ligands in high endothelial venules (HEVs).

147 Lymphocytes are recruited from blood by high-endothelial venules (HEVs).

148 Small venules (high endothelial venules [HEVs]) in inflammatory lesions

149 t Rgs1-/- B cells stick better to lymph node high endothelial venules, home better to lymph nodes, an

150 tion is dependent on direct contact with the high endothelial venule in inflamed lymph node.

151 ng the simultaneous visualization of LVs and high endothelial venules in a lymph node of a living mou

152 nd B cell zones or in close association with high endothelial venules in adult lymph nodes.

153 ) is selectively expressed on endothelium of high endothelial venules in gut and gut-associated lymph

154 s expressed by only a few tissues, including high endothelial venules in lymph nodes, but inflammator

155 tes and sulfated carbohydrates restricted to high endothelial venules in lymph nodes.

156 79 as an inhibitor of lymphocyte adhesion to high endothelial venules in lymphoid organs.

157 eripheral node addressins are upregulated on high endothelial venules in peripheral and mesenteric ly

158 ential interaction with ligands expressed on high endothelial venules in secondary lymphoid organs su

159 ke conduits connect the external lamina with high endothelial venules in T-cell areas and also extend

160 ycans supported the binding of L-selectin to high endothelial venules in vitro and contributed in viv

161 ired for efficient attachment and rolling on high endothelial venules in vivo in both nonstimulated a

162 pendent lymphocyte adhesion to Peyer's patch high endothelial venules in vivo, but the factors respon

163 and mouse T cells, and prevented homing from high endothelial venules into murine LNs.

164 ation through the intercellular junctions of high endothelial venules is lacking.

165 rophils and L-selectin binding to lymph node high endothelial venules is reduced in the absence of ST

166 IL-33 (previously known as NF from high endothelial venules) is an IL-1 family cytokine tha

167 splenic red pulp and the luminal surface of high endothelial venules lacked HA.

168 ctin on lymphocytes with sulfated ligands on high endothelial venules leads to rolling and is critica

169 triad of defects, including overadherence to high-endothelial venules, less interstitial migration an

170 ted as potential recognition determinants on high endothelial venule ligands for L-selectin.

171 the accumulation of IL-12p40 protein around high endothelial venules located in close proximity to p

172 JAM/JAM 2 expression to be restricted to the high endothelial venule of tonsil and lymph nodes, and w

173 -tissue chemokine (SLC), is expressed in the high endothelial venules of lymph nodes and Peyer's patc

174 ocytes binds to peripheral node addressin on high endothelial venules of lymph nodes to mediate leuko

175 omucins that are constitutively displayed on high endothelial venules of lymph nodes.

176 we found that ATX had high expression in the high endothelial venules of lymphoid organs and was secr

177 e to the formation of the MECA-79 epitope in high endothelial venules of mouse lymph nodes.

178 esion molecule (MAdCAM), which is present on high endothelial venules of mucosal lymphoid organs.

179 Interestingly, high endothelial venules of peripheral and mesenteric ly

180 Trafficking across high endothelial venules of peripheral lymph nodes (PLN)

181 ration by mediating lymphocyte attachment to high endothelial venules of peripheral lymph nodes (PLN)

182 ency and velocity of transfectant rolling in high endothelial venules of peripheral lymph nodes using

183 re expressed in endothelial cells lining the high endothelial venules of peripheral lymph nodes, mese

184 ectin, was almost completely absent from the high endothelial venules of these mutant mice, whereas t

185 mor infiltration with a limited induction of high endothelial venules on tumor vasculature, provided

186 show that T cells roll on most Peyer's patch high endothelial venules (PP-HEVs), but preferentially a

187 PBMCs bind in vitro to MECA-79(+) high endothelial venules present in the PVS, suggesting

188 tin/IgM immunohistochemical probe and by the high endothelial venule-reactive monoclonal antibody MEC

189 ysiological shear and is highly expressed by high endothelial venules, specialized vessels involved i

190 tructures that contained B and T cell zones, high endothelial venules, stromal cells, and the chemoki

191 ice displayed enhanced intratumor content of high endothelial venules surrounded by high CD8(+) T-cel

192 as chemokines, regulate the phenotype of the high endothelial venule, the recruitment of lymphocytes,

193 e to enter Ag-stimulated lymph nodes through high endothelial venules, the cellularity of draining ly

194 ells (DCs), and residential macrophages near high endothelial venules, the results highlight critical

195 iates lymphocyte binding to, and rolling on, high endothelial venules; these are prerequisites for th

196 hesion to the luminal surface of specialized high endothelial venules, thus regulating lymphocyte rec

197 s form a network of fibers that radiate from high endothelial venules to all areas of the lymph node

198 ed endothelial cell proliferation, increased high endothelial venule trafficking efficiency and VCAM-

199 ed the B cell follicles while lymphatics and high endothelial venules were found at the B cell/T cell

200 discrete lymphoid aggregates associated with high endothelial venules) were detectable in 9 of 13 hea

201 -1 integrins, and CXCR4 to get access across high endothelial venules, whereas macrophage-1 Ag, LFA-1

202 extravasation of lymphocytes at specialized high endothelial venules within lymph nodes and other le