ライフサイエンスコーパス: high level

1 mps incidence in mainland China remains at a high level.

2 associated with FEV1 in children exposed to high levels.

3 n just over half of cells, but only 20% have high levels.

4 expressed SrtA secretion into the medium at high levels.

5 Among all subjects, aortic high-level 99mTc-tilmanocept uptake was related to nonca

6 's disease neuropathology, and 63 (30%) with high-level Alzheimer's disease neuropathology.

7 r DNs resting-state network; first-level and high-level analyses were performed by using software too

8 Specifically, high-level and perceptual regions must interact to balan

9 High-level APOBEC3A expression is associated with better

10 We conclude that in deaf humans the high-level auditory cortex switches its input modality f

11 ith decreased ceftriaxone susceptibility and high-level azithromycin resistance may bring the threat

12 edictive success stems from its inclusion of high-level but core principles of SC organization: an ov

13 in those runs where resistance had spread to high levels by 500 generations, 56% favoured sequential

14 encoded by the Chi3l1 gene, is expressed at high levels by macrophages during the early stages of ki

15 R-2-hydroxyglutarate (R-2HG), produced at high levels by mutant isocitrate dehydrogenase 1/2 (IDH1

16 s as impossible, and provide a case study of high-level cognitive judgments relying on default implic

17 Compared to their parent strains, high-level colistin resistance mutants (HLCRMs) show red

18 /CXCL10) was among the highest released, and high levels correlated with poor islet transplant outcom

19 High-level DFT calculations reveal that the receptor, ow

20 onfiguration relaxed the system to the logic high level due to self-charge injection into the redox a

21 lcium in old endbulbs may rise to abnormally high levels during high rates of auditory nerve firing,

22 SP5G expression is induced to high levels during long days in wild species, but not in

23 IFNs are produced at high levels during viral infection and have convergent s

24 d in the alphabaculoviruses and expressed at high levels during virus infection.

25 High-level endurance training has been associated with r

26 ur, flavor, taste, visual appearance) was at high level, except for Mahaleb-added ftp.

27 t diagnosed with EVD, 47.6% (229 of 481) had high level exposure (direct contact with a corpse, body

28 While the mechanisms underlying the high-level expression of GATA1 in maturing erythroid cel

29 In specimen of CRC patients, high-level expression of GM-CSF positively correlates wi

30 c activity of venetoclcax for CLL cells with high-level expression of ROR1, indicating that combining

31 High-level expression of the collagen type 1alpha2 subun

32 RGS10 is normally expressed in microglia at high levels, expression is silenced in vitro following a

33 number of early life risk factors, including high levels (extreme 75th percentile for cumulative risk

34 t the detection of mutations associated with high-level fluoroquinolone (OR, 3.99 [95% CI, 1.10 to 14

35 2 categories: a set of mutations that encode high-level FQ resistance and a second set that encodes i

36 ineage-specific super-enhancer, resulting in high-level gene activation.

37 gh flux toward monoterpenes express, at very high levels, genes coding for a unique pair of ferredoxi

38 ssume that decoding follows the same low- to high-level hierarchy of encoding.

39 am to dynamic indentation is maintained at a high level, higher than the resistance of solid silica o

40 sical GAS virulence factor, was required for high-level histone resistance.

41 e up-regulated postnatally and maintained at high levels in adults.

42 own as ZnT-9) is ubiquitously expressed with high levels in cerebellum, skeletal muscle, thymus and k

43 We find that Torso expressed at high levels in cultured Drosophila cells is activated by

44 Clinically, AURKA displays high levels in NSCLC patients, and correlates with poor

45 and prominent cytokines that are present at high levels in the CP microenvironment.

46 Opioid misuse is at historically high levels in the United States, with inhalation (ie, s

47 Common stereotypes associate high-level intellectual ability (brilliance, genius, etc

48 th fMRI when subjects shift thoughts between high-level internally directed cognitive states, when th

49 ino is an open source program written in the high-level language Go.

50 emporal language network and participates in high-level language processing.

51 Here we report that high-level MDM2 but not MDM4 has a consistent critical r

52 These findings indicate that high-level MDM2 expression is needed in order to perform

53 formance and documentation for moderate- and high-level neurologic evaluations.

54 IT achieved about 90%, suggesting relatively high level of adherence.

55 There was a high level of agreement between participants in defining

56 permeation at the in vitro level, finding a high level of agreement with experimental permeation mea

57 elopment in Hong Kong, China, an area with a high level of air pollution compared with other similarl

58 whose tumor cells characteristically show a high level of aneuploidy and genomic instability.

59 Furthermore, we found a high level of aneuploidy in post-mitotic differentiated

60 ed with lifetime reproductive output up to a high level of annual effort.

61 overed that the noisy spiking is linked to a high level of binocular suppression in visual cortex dur

62 Fungal disease diagnosis requires a high level of clinical suspicion and specialised laborat

63 A high level of clinical suspicion is key for early diagno

64 red by the presence of peri-implantitis with high level of concern and low level of therapeutic satis

65 discrimination of the target species with a high level of confidence (99.3%).

66 The high level of consensus shows that there is good agreeme

67 heterometallic bicyclic architectures with a high level of constitutional control.

68 ng organizational culture scale demonstrated high level of construct validity and internal consistenc

69 foldamer secondary structure coupled to the high level of control over the primary sequence results

70 One explanation may be an unusually high level of convergent and parallel evolution (homopla

71 his new public health challenge; and (3) the high level of coordination and collaboration between dif

72 euterated products in good yields and with a high level of deuterium incorporation.

73 Some GBS cases do not exhibit a high level of diagnostic certainty.

74 ficient for efficient diRNA generation and a high level of diRNAs is not necessary for DSB repair.

75 ne feature of high-risk neuroblastoma is the high level of DNA methylation of putative tumor suppress

76 Generalist pollinators experience a high level of environmental variation, which we suggest

77 ly for aligning long reads contaminated by a high level of errors.

78 nce with (68)Ga-DOTATATE PET/CT; n = 4) or a high level of experience (>/=500 scans or >/=5 y experie

79 ESCd display a high level of expression of genes implicated in migratio

80 nalogues obtained by any method and reveal a high level of functional group tolerance for metal-catal

81 cted regions may suggest that a sufficiently high level of herd immunity was reached during the first

82 EK signaling increased expression of KLF5; a high level of KLF5 increased proliferation.

83 To determine whether the high level of LCN2 in the CNS is protective or deleterio

84 by an activity trough at dusk followed by a high level of male courtship during the night.

85 of complex macromolecule synthesis, where a high level of molecular precision or monomer sequence co

86 The high level of orthogonality between FAIMS and MS provide

87 vel of programmed cell death protein 1 and a high level of OX40 were associated with reduced patient

88 60 degrees C with 60 s of activation), and a high level of ozone (13 ppm with 60 s of activation).

89 rway spruce will contribute to maintaining a high level of productivity across many Central European

90 lso suppress T cell activation via producing high level of prostaglandin E2 (PGE2) due to their thous

91 haracterized by low membrane potential and a high level of reactive oxygen species.

92 However, there is a high level of reported missing heritability, where only

93 Especially given the high level of safety of (177)Lu-PSMA radioligand therapy

94 The uptake carrier exhibits a very high level of selectivity towards small substrates inclu

95 Acute myeloid leukemia (AML) cells exhibit a high level of spontaneous apoptosis when cultured in vit

96 ccordingly, C. cohnii was characterised by a high level of sulfur compounds (dimethyl sulfide, ethane

97 A high level of synteny was found with pine genetic maps,

98 genotypes like Nonabokra and Pokkali show a high level of tolerance towards salinity stress compared

99 ased trabeculectomy surgery, although with a high level of uncertainty owing to low event rates.

100 itted parameters to make predictions shows a high level of variability in the modelled number of pand

101 ES nanostructure is retained to a remarkably high level of water (ca. 42 wt % H2 O) because of solvop

102 flammatory response when they are exposed to high levels of a potentially harmful microorganism.

103 te progenitors, but not neuroblasts, express high levels of a T3-inactivating deiodinase, Dio3.

104 d internal Ags while simultaneously inducing high levels of Abs toward hemagglutinin.

105 ding the helicase gene, showing consistently high levels of adaptive evolution, suggesting that they

106 f approximately 1 per 50 bases suggestive of high levels of allelic diversity.

107 k-2 loss-of-function strains have abnormally high levels of AMX-2 compared with wild-type nematodes.

108 These swellings contain high levels of amyloid precursor protein processing enzy

109 lated recombinant allergens in patients with high levels of anti-CCD IgE antibodies.

110 e poorly protective against reinfection, and high levels of antibodies do not always correlate with p

111 ntibodies, low levels of IgA antibodies, and high levels of antibody-dependent cellular cytotoxicity

112 -resistant VCaP (CR-VCaP) xenografts express high levels of AR and retain intratumoral androgen conce

113 rogens in prostate cancer cells that express high levels of AR.

114 WHO guidelines (2004-2013) and had achieved high levels of ART uptake in HIV-diagnosed individuals f

115 Human and mouse HSCs had unusually high levels of ascorbate, which decreased with different

116 The co-opted PK generates high levels of ATP within the viral replication compartm

117 cells stimulated with TLR2 agonists released high levels of ATP.

118 al significance of B7-H4 is supported by the high levels of B7-H4 expression found in numerous tumor

119 mission from nasally colonized pups required high levels of bacterial shedding in nasal secretions an

120 ssion to castration-resistant PCa (CRPC) and high levels of Bag-1L in primary PCa associate with a re

121 Both human and mouse lung ILC2s express high levels of beta1 and beta2 integrin adhesion recepto

122 ey are highly activated effectors expressing high levels of binding to P-selectin, T-bet, and Blimp-1

123 They contain high levels of both HREE and light REE, but are strongly

124 ediate, and near visual acuity, resulting in high levels of both spectacle independence and patient s

125 As high levels of c-di-GMP are associated with the biofilm

126 Men and women reported similar, high levels of career satisfaction, with women reporting

127 DCs recruited at the diseased tissue produce high levels of CCL-2 and IL-8 and contribute to the infl

128 showed that these TREM-2(+) cells expressed high levels of CCR-7 and CD86 suggesting a potential rol

129 The high levels of CD62L expression suggests this molecule c

130 tivation of Hh signaling was associated with high levels of CDK6, pointing to CDK6 as a direct transc

131 enerally exhibit restricted tropism, produce high levels of cell-free virus, and develop susceptibili

132 abolite pro-drug esters, suggesting that the high levels of cellular 2OG may preclude inhibition.

133 n MF input selectivity will be attenuated by high levels of CGC inhibition providing further flexibil

134 rse events, including death, in persons with high levels of circulating Loa loa microfilariae.

135 Treatment models that maintain high levels of clinical effectiveness but allow for incr

136 ly (HHI value of 2500, indicating relatively high levels of competition), duopoly (HHI value of 5000)

137 All 6 antibodies had high levels of concordance (R2 = 0.76-0.99) when using c

138 e social-emotional stimuli, adolescents with high levels of conduct or hyperactivity/inattention symp

139 of sexual partners in the last 7 days, with high levels of consistent condom use with clients and lo

140 Lastly, we showed that high levels of copper (previously shown to elevate CUP1

141 High levels of DAF-16 (in the daf-16 (mu86); muIs61 stra

142 High levels of DDIT4 were significantly associated with

143 removal of condensin I, chromosomes present high levels of de novo Topoisomerase II (TopoII)-depende

144 ls, arising both from experimental noise and high levels of degeneracy or codependency in parameters,

145 immature and mature granulocytes expressing high levels of degranulation markers, were specifically

146 High levels of depression, anxiety and social anxiety oc

147 conditions at room temperature proceeds with high levels of diastereocontrol, leading to beta-amino k

148 Thus, TRalpha absence with high levels of Dio3 provides double-pronged blockage of

149 ervoir of circulating HIV strains exhibiting high levels of diversity and recombination.

150 at combines high levels of step economy with high levels of efficiency and scalability has remained e

151 inyl chlorides are difficult to prepare with high levels of enantiopurity and are prone to undergo de

152 ncluded the flexibility of the approach, the high levels of engagement and responsiveness of patients

153 High levels of ERBB2/HER2 and low levels of ESR1 were as

154 pus tropicalis as a model, we show here that high levels of EVI and MDS/EVI are expressed in the inte

155 Not unexpectedly, saliva samples have high levels of exogenous sequence that can be traced to

156 g is consistent among observers with low and high levels of experience.

157 These results, in combination with the high levels of exposure, indicate a potentially serious

158 Search criteria included high levels of expression, conservation in all parasite

159 as predicted jointly by low levels of SA and high levels of FCA-that is a level of SA lower than woul

160 Importantly, in cancer cells expressing high levels of FGF13, the depletion of FGF13 elicits inc

161 deficient CMD patients, all of which present high levels of fibrosis.

162 Engineered escape variants had high levels of fitness.

163 e number of prominent cell groups expressing high levels of FMRP at the subcortical levels, in partic

164 ons between measurements of OVOCs, including high levels of formic acid, in the atmosphere (measured

165 also HNSCC patients with TP53 mutations and high levels of FOXM1 expression have the poorest surviva

166 ty may become even more important to support high levels of functioning in European forests.

167 n between subpopulations was low, indicating high levels of gene flow, probably due to cross-pollinat

168 We show that gAHB retains high levels of genetic diversity after evolution of gent

169 ylogeographic studies have found evidence of high levels of genetic variation structured across the G

170 Patients demonstrated high levels of HCC-related knowledge (summary score, 77.

171 Strong product binding and high levels of holo-ACPP in the cell identify a potentia

172 ng hematopoietic cells from a pig expressing high levels of human CD47.

173 TH1 polarization, which is characterized by high levels of IFN-gamma.

174 Tolerant Treg cell produced high levels of IL-10 and had diverse T cell receptor Vbe

175 High levels of IL-10 and IL-12/23p40 were significantly

176 Moreover, the association of high levels of IL-15 expression with inflammatory and au

177 ly driven by pathogenic T cells that produce high levels of IL-17 in response to IL-23.

178 In contrast, classical monocytes secreted high levels of IL-6, the blockade of which resulted in i

179 In co-culture systems, MFs secreted high levels of IL-6, while cancer cells produced high le

180 ere the most abundant genera associated with high levels of inflammation in healthy feet.

181 ociated with mononuclear cell infiltrate and high levels of inflammatory cytokine production.

182 the muscle fiber atrophy was associated with high levels of inflammatory cytokines: tumor necrosis fa

183 do not induce pro-inflammatory cytokines and high levels of interferons can be used as scaffolds to c

184 ng from day 15 after HSCT and favored by the high levels of interleukin-15 present in patients' sera,

185 ession of the GLUT5 fructose transporter and high levels of ketohexokinase were identified as molecul

186 ne of the European blood donors tested, have high levels of LAIR1-containing antibodies that dominate

187 um conditions, the calibration curves showed high levels of linearity (R(2)>0.9993) for acrylamide in

188 The malodor was attributable to high levels of methanethiol and dimethylsulfide, the mai

189 re epithelial carcinoma cell lines expressed high levels of MHC-I, low levels of PD-L1, and contained

190 Histopathological analysis revealed high levels of microvascular nestin immunoreactivity in

191 tients with HTR metastatic disease expressed high levels of miR-221.

192 d not be included in our analysis because of high levels of missing data.

193 tin-resistant ovarian cancer cells expressed high levels of MKP-1 and PARP-1 proteins, and that silen

194 High levels of moesin were also observed in muscle biops

195 Because these diseases have high levels of morbidity and can be lethal, it is import

196 remarkable dietary plasticity and consuming high levels of moss, which is exceptionally high in fibr

197 6 mice with hypha-defective strains attained high levels of mucosal colonization but failed to induce

198 ses demonstrate that quiescent MuSCs express high levels of Myogenic Differentiation 1 (MyoD) transcr

199 area of nanofibrous reservoir layers allows high levels of nanoparticle loading.

200 gs provide a framework for rationalizing the high levels of noise in metazoan signaling networks and

201 The set of TADs that are associated with high levels of noncoding conservation exhibit distinct p

202 nd two ancient Irish genomes, we demonstrate high levels of North-West French-like and West Norwegian

203 High levels of OTUD1 inhibit cancer stemness and shut of

204 stressed siblings showed reduced body size, high levels of oxidative damage in lipids and proteins,

205 High levels of PalC localised to sites within the MLNs w

206 Patients reported high levels of patient-centered care: 90% easily underst

207 trongly occupied by CBP and GAGA factor have high levels of paused Pol II, a unique chromatin signatu

208 borted fetuses from sows with PDNS contained high levels of PCV3 (7.57 x 10(7) genome copies/ml), and

209 l subpopulation of human NK cells expressing high levels of PD-1.

210 g EMT markers expressed low levels of MHC-I, high levels of PD-L1, and contained within their stroma

211 Conversely, high levels of PDK1 enhance BCSC properties and are corr

212 adverse birth outcomes is observed with very high levels of pesticide exposure.

213 , when Ambra1 cannot bind to FAK, abnormally high levels of phospho-Src and phospho-FAK accumulate at

214 We present evidence demonstrating that high levels of physical activity predict metabolic flexi

215 High levels of PM2.5 probably contribute to increased T2

216 omes cope with oxidative stress by producing high levels of polyunsaturated fatty acids, oxylipins, a

217 about four or five, but only at moderate-to-high levels of population coverage (>65%) and if systema

218 l Vt, low plateau and driving pressures, and high levels of positive end-expiratory pressure.

219 intimate molecular contacts that explain the high levels of potency and selectivity we have measured.

220 High levels of PPIA were found in the CSF of SOD1(G93A)

221 Low, medium and high levels of predicted extractable total anthocyanin c

222 h Plasmodium yoelii nigeriensis N67C display high levels of pro-inflammatory cytokines and chemokines

223 vered that not only does vaccination provide high levels of protection against lethal aerosol challen

224 High levels of PSY and several other carotenogenic enzym

225 Shh-dependent cell populations that express high levels of Ptchd1 mRNA: cerebellar granule cell prec

226 s with closed neural tubes (nSR-BI(-/-)) had high levels of reactive oxygen species (ROS), intermedia

227 r its activation, leads to the production of high levels of reactive oxygen species in a p38 mitogen-

228 , which counteract the effects of relatively high levels of reactive oxygen species.

229 ealing that P2P networks display exceedingly high levels of reciprocity.

230 tested, RAS at amino acids 28 and 93 led to high levels of resistance.

231 trace metals, organic compounds, and often, high levels of salts.

232 se Gmsacpd-c mutants were identified to have high levels of seed, nodule, and leaf stearic acid conte

233 e nanomolar inhibition of NaV1.7 and exhibit high levels of selectivity over other sodium channel iso

234 for VEGF and 1-100ng/mL for PSA), as well as high levels of sensitivity and selectivity (i.e., resist

235 at uninfected Irgm1-deficient mice displayed high levels of serum cytokines typifying profound autoin

236 re capable of IL-17 production and expressed high levels of signature genes of the TH17 pathway, RORg

237 Rs, containing 50 nM or 100 nM siRNA, showed high levels of silencing, particularly in primary airway

238 ther low levels of the dual-stained cells or high levels of single-stained cells, and such patterns d

239 but it is difficult to achieve exceptionally high levels of site-selectivity.

240 Unexpectedly, we discover high levels of somatic hypermutation in infants as young

241 Consistently, restoring high levels of SOX5/6/21 in human primary glioblastoma c

242 nomical syntheses, a synthesis that combines high levels of step economy with high levels of efficien

243 , and the most useful syntheses will combine high levels of step-economy with efficiency and scalabil

244 enantioenriched form for the first time with high levels of stereocontrol, and this technology is app

245 ote nitrogen and sulfur functionalities with high levels of stereocontrol.

246 tereogenic alpha-keto esters was achieved in high levels of stereoselectivity, affording versatile te

247 Extremely high levels of Streptococcus mutans were detected in the

248 erleukin 17 (IL-17) production as well as by high levels of T-bet and related orphan receptor 3 expre

249 tional chemotherapy for cancer patients with high levels of TCTP expression.

250 Ecological theory predicts that high levels of temporal autocorrelation in the environme

251 Developmentally, males are exposed to high levels of testosterone and its byproduct, estradiol

252 levels of IL-6, while cancer cells produced high levels of TGF-beta.

253 Populations with high levels of the 2L+(a) allele may form reservoirs of

254 Circulating monocytes uniformly express high levels of the canonical E-selectin binding determin

255 n immature NK cell population that expressed high levels of the coinhibitory molecules PD-1, Lag-3, a

256 We record high levels of the dung fungus Sporormiella, a proxy for

257 ient Mtb cultured on fatty acids accumulated high levels of the ICL aldehyde endproduct, glyoxylate,

258 dings show that human melanoma cells express high levels of the immune checkpoint molecule CTLA4, wit

259 engaging the T cell receptor (TCR), express high levels of the immunosuppressive cytokine IL-10, but

260 tissues, we find that cancer cells depend on high levels of the iron-sulfur cluster biosynthetic enzy

261 Relatively high levels of the main regulated mycotoxins and presenc

262 ry tumor, tumor cell cultures expressed very high levels of the Myc protein and, in contrast to all o

263 rice, is highly nutritious but contains very high levels of the non-threshold carcinogen inorganic ar

264 osis, extensive CD4 T cell accumulation, and high levels of the proinflammatory factors IFN-gamma, TN

265 bolomic profiling and uncovered unexpectedly high levels of the sesquiterpene volatile beta-selinene

266 Treg cell precursors expressed high levels of the tumor necrosis factor receptor superf

267 ivers of MAT1A-KO mice were characterized by high levels of triglycerides, diglycerides, fatty acids,

268 tation was characterized by three stages: i) high levels of tryptamine, phenolics, and scavenging cap

269 er lesions in biopsy specimens or persistent high levels of tTGA.

270 ISG15 deficiency also leads to persistently high levels of type I IFN-stimulated gene expression and

271 neoplasia in mouse prostate with aberrantly high levels of Ube2e1 in the cytoplasm.

272 The CSC-like properties were correlated with high levels of unphosphorylated IFN-stimulated gene fact

273 Feeding with ADM leads to high levels of viable egg production, but also does not

274 Mice with high levels of viremia had HBV-infected liver progenitor

275 EVD is characterized by high levels of virus replication and dissemination, dysr

276 vestigated factors mediating these extremely high levels of VSG expression by inserting ectopic VSG11

277 ival curves and log-rank tests revealed that high levels of WIF1 methylation were associated with low

278 , we generated a stable cell line expressing high levels of ZIKV prM-E proteins that constitutively p

279 s within the 530 bp that are responsible for high-levels of ltxA expression.

280 TDP genes are constitutively expressed at high levels or induced during desiccation in multiple ta

281 The purpose of this article is to provide a high-level overview of what is known about tuberculosis

282 We also identify the high-level path selection rules nature seems to use when

283 bility, the integration processes underlying high-level perception are much less understood.

284 These findings suggest that high-level post-conventional moral reasoning is associat

285 However, high-level production of HBc particles in bacteria is de

286 ction, low-temperature NMR spectroscopy, and high-level quantum chemical calculations.

287 scription of the transformation from low- to high-level representations of facial identity in human f

288 providing a clear identification of low- and high-level rule representations.

289 ed for the increased burden of fungus in the high-level samples.

290 The SB system enables high-level stable gene transfer and sustained transgene

291 ug environment they promote the evolution of high-level, target-based resistance.

292 We analyzed both high level terms (HLT) and preferred terms (PT) for frac

293 DiD-NCM had similar high-level uptake in tumor with DiD-BCM within the first

294 ctivity against bacterial strains possessing high level vancomycin resistance mediated by the reprogr

295 Those recommendations provided a high-level view of how to accelerate the conversion of n

296 y confined to a subset of the visual system (high-level vision: faces, scenes) and relatively late in

297 nvestigated children (4 years and older) and high-level visual areas.

298 on speed, indicating that both low-level and high-level visual properties of the adapting stimulus co

299 Fluorescent marker proteins are expressed at high levels within 1 week, and a proof of efficient func

300 The ITS repeats generally exhibit high-level within-individual homogeneity, while relative