ライフサイエンスコーパス: high myopia

1 en associated with patients with moderate to high myopia.

2 an important factor in preventing congenital high myopia.

3 The latter two were also predictors of high myopia.

4 ht vision, mild photophobia, and moderate to high myopia.

5 ascular features of the choroid in eyes with high myopia.

6 gene are causally related to MYP2-associated high myopia.

7 eneficial for subfoveal lesions secondary to high myopia.

8 ethnic origin, positive family history, and high myopia.

9 lose the macular hole in MH-associated RD in high myopia.

10 sion loss among almost 1 billion people with high myopia.

11 y, contractures, mild skeletal dysplasia and high myopia.

12 ht-threatening complications associated with high myopia.

13 tant is likely to contribute to the onset of high myopia.

14 mmon fundus findings among Asian adults with high myopia.

15 mican gene polymorphisms could be related to high myopia.

16 ns (Visian ICL) implantation for moderate to high myopia.

17 ially associated with choroidal thickness in high myopia.

18 inically, was identified in 2 eyes (1%) with high myopia.

19 .32 x 10(-3)), a region previously linked to high myopia.

20 etinas of amblyopic children with unilateral high myopia.

21 iduals presented with excavated optic discs, high myopia (-1.00 to -16.00 diopters), and increased ax

22 D [SD 4.49]); rod dominated dystrophies (OR high myopia 10.1, P < .0001; OR high hyperopia 9.7, P =

23 se subjects also having the highest rates of high myopia (11.8%) and astigmatism (53.4%).

24 eral chromosomal regions have been linked to high myopia (12q, 17q, and 18q), to quantitative refract

25 , followed by cone-dominated dystrophies (OR high myopia 19.5, P < .0001; OR high hyperopia 10.7, P =

26 n [15.2%-31.5%]) and 163 million people with high myopia (2.7% of the world population; 95% CI, 86-38

27 were associated with the highest risk of SE high myopia 239.7; odds ratio (OR) mild hyperopia 263.2,

28 e prevalence of myopia (30.2% vs 23.4 %) and high myopia (4.8% vs 2.5%) were higher in second-generat

29 P = .02; OR: 0.18 [95% CI: 0.05, 0.68]) and high myopia (9% +/- 6% vs 42% +/- 10%; P = .01; OR: 0.13

30 I, 43.4%-55.7%]) and 938 million people with high myopia (9.8% of the world population; 479-2104 mill

31 In high myopia, a region resembling the myopic peripapillar

32 ease (most severe) were at greatest risk for high myopia, absence of binocular fusion, dyskinetic str

33 In eyes with high myopia, after adjusting for age, choroidal vascular

34 High myopia, age-related macular degeneration, or prosta

35 e mechanism of the macular changes is due to high myopia, amblyopia, or a combination of the two.

36 vertical gaze shifts in patients with axial high myopia and a posterior shift from abduction to addu

37 th ROP, the association of early, persistent high myopia and an elevated threshold at 10 degrees was

38 the cornea and sclera in chickens developing high myopia and astigmatism induced by form deprivation.

39 The overall rates of high myopia and astigmatism were 4.6% and 45.0%, respect

40 special needs children who have moderate to high myopia and difficulties wearing glasses or contact

41 Genomic DNA from five pedigrees (with high myopia and either protanopia or deuteranopia) that

42 eta-analysis of the prevalence of myopia and high myopia and estimated temporal trends from 2000 to 2

43 degrees of clarity in 25 eyes (18%): 17 had high myopia and extensive parapapillary atrophy.

44 a broad range (SD: 4.67 D) and included both high myopia and high hyperopia.

45 ropia; rates were 3.6% and 2.0% for moderate-high myopia and hyperopia, respectively.

46 excavated optic disc anomaly associated with high myopia and increased axial length.

47 edecessors for the correction of moderate to high myopia and maintenance of safe IOP levels without i

48 utosomal-recessive syndrome characterized by high myopia and sensorineural deafness.

49 Contrast sensitivity declines with age, high myopia, and astigmatism.

50 Younger age, high myopia, and male sex continue to be associated with

51 ociated with younger age at time of surgery, high myopia, and male sex in several large retrospective

52 y (9 of 13, 70%) of patients had moderate-to-high myopia, and none were using protective eyewear when

53 dness or photophobia, reduced visual acuity, high myopia, and nystagmus.

54 usion, choroidal neovascularization (CNV) in high myopia, and other causes of CNV.

55 Most of these individuals also have high myopia, and some have retinal dystrophy and patchy

56 of retinal pigment epithelium (RPE) humps in high myopia, and to describe the distinctive features fr

57 our loci for nonsyndromic autosomal dominant high myopia at 18p11.31, 12q22-q23, 17q21-q23, and 7q36.

58 yperopia to 33.7% (standard error, 0.08) for high myopia at 85 years of age.

59 een noted to demonstrate increasing rates of high myopia at earlier ages, sometimes with associated v

60 s a known candidate gene for MYP2-associated high myopia, based on its mapped location within the MYP

61 oroidal vascularity was greater in eyes with high myopia (beta = 0.032, P < .001).

62 on refractive lens exchange and cataract in high myopia between 1996 and 2004 included some 2036 eye

63 w variations in the prevalence of myopia and high myopia between regions and ethnic groups, and there

64 Odds ratios (ORs) for myopia and high myopia by birth order, using logistic regression an

65 impairment will occur if uncorrected, whilst high myopia causes sight-threatening complications.

66 and stability of refraction in patients with high myopia compared with similar short-term studies.

67 etoid, hypotonic, and ataxic) more often had high myopia, CVI, dyskinetic strabismus, and gaze dysfun

68 ung men (mean age 21.59 +/- 1.15 years) with high myopia (defined as -6.0 diopter [D] or worse, mean

69 ncoded TGIF gene for MYP2 autosomal dominant high myopia did not identify sequence alterations associ

70 th order was associated with both myopia and high myopia (eg, comparing first- vs second-born individ

71 Myopia and high myopia estimates from 2000 to 2050 suggest signific

72 We suggest naming this entity high myopia-excavated optic disc anomaly.

73 underwent cataract surgery with a history of high myopia, eye trauma, or retinal detachment was 0.49%

74 The high myopia group mean age was 54.4 +/- 18.2 years (rang

75 In the high myopia group, axial length had the best correlation

76 Mild myopia and moderate to high myopia groups were negatively associated with devel

77 Very high myopia (>/=-8.00 D) occurred in zone I in 2 of 52 (

78 Among risk factors evaluated, high myopia (>/=6 diopters; odds ratio [OR], 5.7; 95% CI

79 pared with those with emmetropia, those with high myopia had a significantly increased lifetime risk

80 High myopia had been present since age 18 months or youn

81 Although lens surgery for high myopia has a long History, it has been extremely co

82 A locus for autosomal dominant pathologic high myopia has been mapped to 18p11.31.

83 The genetic basis for congenital high myopia has frequently been connected to mutations i

84 Of all refractive errors, high myopia has the most severe visual consequences.

85 orrhage during pars plana vitrectomy include high myopia, history of previous retinal detachment surg

86 Retinal detachment was associated with high myopia (HR, 6.12; 95% CI, 5.84-6.41), vitrectomy fo

87 rs (D)/> +0.5 D, and the cutoff for moderate-high myopia/hyperopia was 3.0 D.

88 ed from -25 to +14 diopters; 796 persons had high myopia (ie, a spherical equivalent of -6 diopters o

89 A total of 23 eyes with high myopia implanted with an angle-supported phakic IOL

90 has been identified in a number of cases of high myopia, implicating it in the aetiology of this dis

91 view, 16 years [range, 2-38 years]), all had high myopia in at least 1 eye and severely reduced visio

92 PD) to estimate the prevalence of myopia and high myopia in each country of the world.

93 d to be a candidate gene for MYP2-associated high myopia in single-nucleotide polymorphism studies.

94 ess the place of refractive lens exchange in high myopia in the light of more recent reports in the l

95 A sibling pair had unilateral high myopia in their right eyes and near emmetropia in t

96 (-/-)Fmod(-/-) mice show certain features of high myopia: increased axial length, thin sclera, and re

97 High myopia is a common complex-trait eye disorder, with

98 Although high myopia is a strong risk factor for glaucoma subtype

99 Congenital high myopia is an early-onset enlargement of the eye glo

100 uggests that choroidal thinning in eyes with high myopia is associated with the reduction in both its

101 l history of choroidal neovascularization in high myopia is variable, and reports to date have some c

102 ci, including three previously identified AD high-myopia loci on 18p11.31, 12q22-q23, and 7q36.

103 identified risk factors include keratoconus, high myopia, low residual stromal bed thickness from exc

104 ce of myopia < or = -1.0 D was 16.8%, and of high myopia < or = -5.0 D, 2.4%.

105 myopia (-1.0 D to -2.99 D), and moderate to high myopia (</=-3.0 D).

106 D) and 11 (11.7%) were categorized as having high myopia (</=-5.00 D).

107 Very high myopia occurred in zone II posterior in 1 of 58 (1.

108 f myopia of -0.50 diopter (D) or less and of high myopia of -5.00 D or less, projected to the year 20

109 e a refractive surgery option for those with high myopia or astigmatism.

110 ascular Inner Retinal Defect Associated With High Myopia or Epiretinal Membrane," published online Ja

111 "Pathologic" high myopia, or myopia of <=-6.00 diopters, predisposes

112 High myopia, or pathologic myopia, usually refers to a c

113 .004), and higher proportions of moderate to high myopia (P < 0.001) were found in patients with mirr

114 keratomileusis in patients with moderate and high myopia, particularly in the areas of visual quality

115 ients 18 to 49 years of age with moderate to high myopia (preoperative corrected distance visual acui

116 Patients with diabetes mellitus, glaucoma, high myopia, pseudoexfoliation, traumatic cataract, subl

117 % CI, 1.06-1.25; P = 4.60E-04 for myopia and high myopia, respectively) and the apparent dose respons

118 % CI, 1.11-1.30; P = 3.60E-06 for myopia and high myopia, respectively).

119 -0.5 diopter (D) for myopia, and < -5 D for high myopia, respectively.

120 erited disorder classically characterized by high myopia, retinal detachment, and occipital encephalo

121 Eyes with high myopia (SE <-6.0 D) were more likely to have POAG (

122 A total of 120 eyes of 83 patients with high myopia (spherical equivalent >/=-6 diopters or axia

123 Amblyopic children with unilateral high myopia tend to have a thicker fovea and thinner inn

124 In patients with moderate to high myopia, the AcrySof Cachet angle-supported pIOL pro

125 -cone dystrophy, a mild learning difficulty, high myopia, three limb post-axial polydactyly, horsesho

126 We now report significant linkage of high myopia to a second locus at the 12q21-23 region in

127 acquired conditions such as angioid streaks, high myopia, trauma, choroidal tumors, familial macular

128 The findings provide an explanation for high myopia, vitreoretinal degeneration and retinal deta

129 Incidence of moderate-high myopia was also related to baseline age, nuclear op

130 High myopia was defined as myopic refractive error of </

131 defined as SE of -1.0 diopters (D) or less; high myopia was defined as SE of -5.0 D or less; any hyp

132 More very high myopia was found in eyes that received laser treatm

133 The most common disc finding associated with high myopia was peripapillary atrophy (81.2%), followed

134 yopia-related macular finding in adults with high myopia was staphyloma (23%), followed by chorioreti

135 ited Kingdom and Israel suggested myopia and high myopia were approximately 10% more common in first-

136 Myopia and high myopia were defined as autorefraction of -0.75 diop

137 Myopia and high myopia were defined as spherical equivalents (SE) o

138 Adults 40 years and older (n = 359) with high myopia were pooled from 3 population-based surveys

139 who require laser treatment may develop very high myopia, which has considerable clinical consequence

140 precious stroma in eyes with thin corneas or high myopia, which otherwise may not qualify for LASIK.

141 retrospective study involving eight cases of high myopia with foveoschisis and foveal detachment in w

142 X-linked high myopia with mild cone dysfunction and color vision

143 uscle weakness and bone dysplasia as well as high myopia, with evidence of clinical improvement of mo

144 tive surgeries in patients with moderate and high myopia, with or without astigmatism, especially in

145 de a hierarchy of risk factors for RD onset: high myopia, young age, capsular rupture, history of eye