ライフサイエンスコーパス: high-protein

1 Subjects were offered 2 high-protein (30% of energy) ad libitum diets, each for

2 energy intake was significantly lower in the high-protein (7.21 +/- 3.08 MJ/d) condition than in the

3 d carrots (Daucus carota) is determined by a high protein abundance of the rate-limiting enzyme for c

4 Notably, we present a system with high protein abundance that nevertheless requires a prob

5 We focus on low mRNA numbers, high protein abundance, and monomeric transcription-fact

6 The high protein acid load affected bone turnover, as indica

7 Furthermore, bone metabolism is altered by a high-protein acidogenic diet, presumably to buffer the a

8 ifferentiation, the initial segment exhibits high protein and activity levels of phosphatase and tens

9 in corn-broad bean spaghetti-type pasta with high protein and dietary fibre content and adequate qual

10 follow-up of a randomized trial of prenatal high protein and energy supplementation conducted betwee

11 gnancy low-carbohydrate dietary pattern with high protein and fat from animal-food sources is positiv

12 gnancy low-carbohydrate dietary pattern with high protein and fat from vegetable food sources is not

13 The high protein and fiber content of intermediate wheatgras

14 t versus high fat and average protein versus high protein and in the comparison of highest and lowest

15 olorants in complex food matrices presenting high protein and/or fat content.

16 nservatively, with dietary support including high-protein and low-fat diets supplemented with medium-

17 s scenario, that host plant N enrichment and high-protein artificial diets decreased the size and via

18 itivity), oxidation of analyte on drying and high protein binding (low recovery), ODN affinity to exp

19 ith a low packing density is used to achieve high protein binding capacity.

20 ource and adsorbed to a porous membrane with high protein binding capacity.

21 ood samples for all studied compounds with a high protein binding index.

22 was greatly limited by rapid metabolism and high protein binding, although antifibrotic effects with

23 is particularly problematic because of their high protein binding.

24 and also, protein-bound solutes, exhibiting high protein-binding affinity and dependence on tubular

25 se of standard assays.The consumption of the high-protein breakfast before the white-bread challenge

26 The high-protein breakfast resulted in a lower insulin AUCi

27 GSD II treated only with a low-carbohydrate/high-protein, calorie-balanced diet.

28 ains taken under study were found to posses' high protein, carbohydrates, minerals, crude fibers, pol

29 usion, high protein expression of CXCL16 and high protein co-expression of CXCL16/CXCR6 in PC were in

30 e particularly suitable for situations where high protein concentration and long-term stability are r

31 ucture that provides optimal balance between high protein concentration and low resonance energy tran

32 However, at neutral pH under high protein concentration conditions, aggregation and p

33 Cell-free protein expression allowed (i ) high protein concentration in the membrane, (ii ) contro

34 Results showed that high protein concentration led to formation of larger WP

35 quire single protein isolation from within a high protein concentration milieu.

36 Tetramerization occurs spontaneously at high protein concentration or upon addition of the phosp

37 rements as a novel tool for analyzing PPI in high protein concentration systems.

38 Despite the high protein concentration within the complex coacervate

39 We hypothesize that this high protein concentration, like that of Rubisco, is nec

40 Therefore, once RhaS reaches a relatively high protein concentration, presumably sufficient to sat

41 and fluorescence as well as FTIR, at low and high protein concentration, respectively, were carried o

42 At high protein concentration, the complex forms larger ass

43 the tendency to form a non-swapped dimer at high protein concentration.

44 e highest affinity sites under conditions of high protein concentration.

45 ormation of off-pathway soluble oligomers at high protein concentration.

46 a promising description of behavior at very high protein concentrations (approximately 250 g/L), sug

47 At high protein concentrations a significant lag in time wa

48 However, lysis at high protein concentrations allows partial recovery of t

49 throughput format, such as a requirement for high protein concentrations and a high coefficient of va

50 icle concentrations, high ionic strength, or high protein concentrations and are spectrally compatibl

51 ch results in the need for unphysiologically high protein concentrations and large ligand:protein rat

52 gates supported the presence of tetramers at high protein concentrations and monomers at low protein

53 At very high protein concentrations compared to the DNA concentr

54 pensity to form amyloid fibers at relatively high protein concentrations in the presence of Cu and be

55 depletion of the inhibiting compounds due to high protein concentrations needed for detectable bindin

56 its in vitro and to test the hypotheses that high protein concentrations or retinal homogenate increa

57 The protein binds cooperatively and at high protein concentrations protects secondary sites tha

58 Aggregates formed at high protein concentrations showed slower degradation ra

59 nger stable, such as denaturing solvents and high protein concentrations where macromolecules tend to

60 t require room temperature conditions and/or high protein concentrations, and thus it will allow more

61 Even at high protein concentrations, every gA dimer requires con

62 hich encompass amyloid-promoting conditions (high protein concentrations, high temperatures, acidic p

63 At high protein concentrations, NFs align to form a nematic

64 High protein concentrations, osmolytic crowding agents,

65 We find that at high protein concentrations, rotational diffusion is dec

66 At high protein concentrations, the rate of fibril formatio

67 HPLC studies confirm ligand cleavage at very high protein concentrations, they indicate that hydrolys

68 ough nonspecific oligomerization occurred at high protein concentrations.

69 ration and is universally suppressed at very high protein concentrations.

70 reases the lifetime of the ferryl species at high protein concentrations.

71 alt buffers but the protein was insoluble at high-protein concentrations in 0.1 M NaCl.

72 itution conditions (such as nonphysiological high-protein concentrations or unrealistically small lip

73 = 0.026) over the day were attenuated in the high-protein condition compared with the normal-protein

74 xpression during human embryogenesis and the high protein conservation from mouse to human implicate

75 Freeze-dried hydrolysate had a high protein content (89.02%, dry weight basis) and it w

76 ulation of functional foods not only for its high protein content but also by the biological and func

77 However, the high protein content of serum poses significant challeng

78 High protein content sport nutritional supplements are f

79 aw material for the process, and presence of high protein content with good amino acid balance and bi

80 Meat has a high protein content, but the small amounts of meat need

81 ectroscopic effects, which were abolished at high protein contents of 10 wt %.

82 circuits that best suppress variability: (i) high protein cooperativity and low miRNA cooperativity,

83 mensional metal oxide environment allows for high protein coverage (26 times an ideal monolayer cover

84 colorectal cancer samples is feasible, with high protein coverage.

85 moose movement into cropland is mediated by high-protein crops, but not by thermoregulatory habitat

86 lations of small vesicles (or micelles) with high protein densities and curvature stress created upon

87 ons yield slow but efficient lipid mixing at high protein densities and variable amounts of lipid mix

88 While high protein density and planar membrane morphology are

89 e to the absence of the viral genome and its high protein density.

90 At high protein/detergent ratios, the SN-CCK4 fusion protei

91 trostatic calculations required the use of a high protein dielectric constant of 10 or higher.

92 Ingestion of a high protein diet did not result in increased production

93 group (6.05 kg; 95% CI, 4.84-7.26 kg) or the high protein diet group (6.51 kg; 95% CI, 5.23-7.79 kg)

94 e maple syrup urine disease mice placed on a high protein diet that mimics the catabolic stress shown

95 On a high protein diet, mutant mice display disease exacerbat

96 ; continuous feeding of a high carbohydrate, high protein diet, preferably by the enteral route; and

97 ur during long-term calorie restriction or a high protein diet.

98 n diet: 160 kcal/d [95% CI, 102-218 kcal/d]; high protein diet: 227 kcal/d [95% CI, 165-289 kcal/d])

99 rotein diet: 2.87 kg [95% CI, 2.11-3.62 kg]; high protein diet: 3.18 kg [95% CI, 2.37-3.98 kg]) incre

100 er after the low-protein diet than after the high-protein diet (253 +/- 70 compared with 225 +/- 63 g

101 ardiovascular effects of a low-carbohydrate, high-protein diet (LCHP) in the ApoE(-/-) mouse model of

102 eduction in fasting insulin when consuming a high-protein diet (P = 0.03).

103 stration increased slightly in animals fed a high-protein diet (protein content 39.4%).

104 (liver FXR-knockout mice) were re-fed with a high-protein diet after 6 hours fasting and gavaged a (1

105 The high-protein diet also reduced the pupal lethality and t

106 bserved lifespan extension is prevented on a high-protein diet and in FoxO-null flies.

107 A high-protein diet caused cortical localization of TRPML,

108 y was markedly increased with the isocaloric high-protein diet despite an unchanged leptin AUC.

109 sistent FoxO activation can be reversed by a high-protein diet in adulthood, through mTORC1 and GCN-2

110 Our data suggest that a high-protein diet may be beneficial for weight loss and

111 resistance and beta cell function, whereas a high-protein diet may be more beneficial for white patie

112 ting that the much-maligned low-carbohydrate-high-protein diet may have a salutary effect on the epid

113 and raise the intriguing possibility that a high-protein diet might reduce the severity of MLIV.

114 ce receiving an isonitrogenic and isocaloric high-protein diet or the AIN-93M diet, and wild-type mic

115 on was prevented when the rats were fed on a high-protein diet rich in glutamine, arginine, fish oil,

116 We evaluated whether an energy-restricted high-protein diet with a low glycemic index and soluble

117 In animals receiving a high-protein diet with low SAA content, the kidney excre

118 eased by 3.7 +/- 0.4 kg with the ad libitum, high-protein diet, despite a significantly decreased lep

119 In liver FXR-knockout mice on a high-protein diet, the plasma concentration of newly for

120 ition, and fat distribution in response to a high-protein diet, whereas an opposite genetic effect wa

121 increased survival in mice challenged with a high-protein diet, which exacerbates disease.

122 increase in HDL seen in all diets except the high-protein diet.

123 activating TORC1 or by feeding the larvae a high-protein diet.

124 days, vs. almost 0% survival on the low-fat/high-protein diet.

125 ngs and appetite scores in participants with high-protein-diet intake (P = 0.027 and 0.047, respectiv

126 ificantly elevated blood ammonia levels with high-protein dietary feeding.

127 special composition of the novel flour with high protein, dietary fiber and fat content results in a

128 Here, we show that high protein diets are lethal to 4-week-old and 8-week-o

129 ffects of normal protein (control) diet with high protein diets containing whey, or its fractions lac

130 increased significantly with the normal and high protein diets.

131 However, consuming high-protein diets (1.6-2.4 g/kg per day), or high-quali

132 ily energy) showed stronger effects than did high-protein diets (25% of daily energy) on reducing con

133 = 658), meal replacements (4 arms; n = 322), high-protein diets (6 arms; n = 865), dietary supplement

134 Although high-protein diets (HPDs) are frequently consumed for bo

135 tention has been focused on low-carbohydrate-high-protein diets (LC-HP) and their potential impact on

136 high-fat than with the high-carbohydrate or high-protein diets (P <or= 0.1).

137 low-carbohydrate, low-GI, Mediterranean, and high-protein diets all led to a greater improvement in g

138 Low-carbohydrate, high-protein diets appear to improve satiety through the

139 Low-carbohydrate, low-GI, Mediterranean, and high-protein diets are effective in improving various ma

140 kg; median duration: 12 mo (10-26 mo)], and high-protein diets by 1.5 kg [95% CI: 0.8, 2.1 kg; media

141 Thus, the acid load associated with high-protein diets causes a concerted response of variou

142 sponse of acid excretory pathways in mice to high-protein diets containing normal or low amounts of a

143 a demonstrate that short-term consumption of high-protein diets does not disrupt calcium homeostasis

144 omeostasis and bone turnover are affected by high-protein diets during weight maintenance (WM) and ED

145 Low-carbohydrate, high-protein diets favorably affect body mass and compos

146 Widespread popularity of high-protein diets has drawn controversy as well as scie

147 High-protein diets increase weight loss (WL) during ener

148 Low-carbohydrate, high-protein diets may be an effective choice for weight

149 Vegetarian and meat-based high-protein diets may have contrasting effects on appet

150 ns have been raised regarding the effects of high-protein diets on bone health.

151 The long-term safety of low-carbohydrate, high-protein diets on cardiovascular disease risk remain

152 ormula diets have been shown to elevate, and high-protein diets to depress, the tryptophan-LNAA ratio

153 Anti-obesity drugs, meal replacements, and high-protein diets were associated with improved weight-

154 c index (GI), high-fiber, Mediterranean, and high-protein diets with control diets including low-fat,

155 were observed in rats fed ketogenic diets or high-protein diets, but AQP9 levels were elevated in liv

156 several nutritional interventions, including high-protein diets, caloric supplementation, calcium and

157 tion and absorption by individuals consuming high-protein diets, particularly when the calcium conten

158 High-protein diets, rich in methionine and branched chai

159 Long-term adherence to high-protein diets, without discrimination toward protei

160 ent years have seen strong tendencies toward high-protein diets.

161 consume relative to energy requirements from high-protein diets.

162 een considerable interest in the benefits of high-protein diets.

163 Although a mutant exhibiting high-protein digestibility and lysine content has market

164 These data suggest high protein divergence between species and rapid change

165 ronutrient beverage can be as effective as a high-protein dose (25 g) at stimulating increased MPS ra

166 High-protein enteral nutrition enriched with immune-modu

167 with immune-modulating nutrients vs standard high-protein enteral nutrition, initiated within 48 hour

168 Based on these results, AgNP toxicity in high protein environments (e.g., wastewater) is expected

169 st that efficient translation initiation and high protein expression are aided by reduced secondary s

170 ZNP delivery of mRNA results in high protein expression at low doses in vitro (<600 pM)

171 that gene amplification was associated with high protein expression for both genes and that protein

172 High protein expression of BUB1, BUB3, and CDC42 in low-

173 High protein expression of coinhibitory molecules PD1, C

174 As a conclusion, high protein expression of CXCL16 and high protein co-ex

175 patients in the Mayo Clinic cohort with EZH2-high protein expression were 1.4 times more likely to ex

176 Patients in the Mayo Clinic cohort with EZH2-high protein expression were nearly two times more likel

177 Southwestern Medical Center cohort with EZH2-high protein expression were two times more likely to ex

178 etically incorporated into histone H3 with a high protein expression yield.

179 r fluorescence endoscopy because it showed a high protein expression, especially in sessile serrated

180 gene sequences to maximize the likelihood of high protein expression.

181 om a distal promoter, which is necessary for high protein expression.

182 al contamination and transforming waste into high-protein feed that can replace increasingly more exp

183 ow-protein diet, food preferences for savory high-protein foods were enhanced.

184 it and vegetables; grains other than cereal; high-protein foods, including beans, legumes, and soy; f

185 e and that these involve selection of savory high-protein foods.

186 pite the popularity of the low-carbohydrate, high-protein, high-fat (Atkins) diet, no randomized, con

187 effects and mechanisms, a low-carbohydrate, high-protein, high-fat diet may be considered a feasible

188 domly assigned to either a low-carbohydrate, high-protein, high-fat diet or a low-calorie, high-carbo

189 -based diet, high in fruit and vegetables; a high-protein, high-fat diet, high in meats, eggs, fried

190 erm safety and efficacy of low-carbohydrate, high-protein, high-fat diets.

191 The high-protein, high-fat, and high-carbohydrate diets cont

192 ts were studied after 3 wk of diets with 50% high protein (HiPro) and 20% control (CON) casein-provid

193 otein (MHP; 25% of energy from protein), and high protein (HP, 50% of energy from protein).

194 The objective was to examine whether a high-protein (HP) compared with a normal-protein (NP) br

195 of this study was to compare the effect of a high-protein (HP) diet to a standard-protein (SP) diet i

196 ial effects on weight loss and blood lipids, high-protein (HP) diets have been shown to increase insu

197 veloped than in developing countries because high-protein (HP) Western diets induce metabolic acidosi

198 a normal-protein [NP (control); n = 23] or a high-protein (HP; n = 21) (0.8 compared with 1.5 g . kg(

199 of TSH antigens were employed to demonstrate high protein immobilization and high antigen detection c

200 tered vitamin K usage or glucose regulation (high protein-induced vitamin K antagonist-II).

201 on to either low protein intake (LOW PRO) or high protein intake (HIGH PRO) on the postprandial muscl

202 High protein intake during infancy may contribute to obe

203 In a population with relatively high protein intake during pregnancy, higher protein int

204 There is emerging evidence that high protein intake during the first 2 y of life is a ri

205 It therefore seems prudent to avoid a high protein intake during the first 2 y of life.

206 Various purine-rich foods and high protein intake have long been thought to be risk fa

207 Only in those children with high protein intake in our population (i.e., >42 g/d), a

208 ever, renal function decreases with age, and high protein intake is contraindicated in individuals wi

209 diposity, suggesting that potential risks of high protein intake may differ between breastfed and for

210 The objective was to ascertain the effect of high protein intake on insulin-like growth factor I (IGF

211 High protein intake was not associated with renal functi

212 In multivariate linear regression analyses, high protein intake was not significantly associated wit

213 in dogs by salt and water restriction, or a high protein intake.

214 ervational human studies have suggested that high-protein intake may increase CKD progression and eve

215 High-protein intake may positively impact bone health by

216 about kidney-damaging effects of long-term, high-protein intake.

217 d be considered before and during long-term, high-protein intake.

218 t average protein intakes (72 g/d) to 70% at high protein intakes (212 g/d).

219 Excess acid generated from high protein intakes increases calcium excretion and bon

220 nly distributed protein intakes and men with high protein intakes showed higher LM or aLM throughout

221 There is little evidence that links high protein intakes to increased risk for impaired kidn

222 ressed in >70% of breast tumors and that its high protein level correlates well with tumor histologic

223 Western analysis showed a high protein level of ABCA7 in mouse spleen, lung, adren

224 on characterized by the existence of low and high protein levels ("off" and "on" levels, respectively

225 scapigera, LFY-specific antibodies detected high protein levels in developing flowers but not in the

226 he subcellular fractions studied both showed high protein levels of hnRNP F in colon tumors compared

227 PTEN KO cells were found to have high protein levels of PFKFB3, which directly contribute

228 Immunoblot analysis revealed collectively high protein levels of prosurvival Bcl-2 members in cell

229 However, vesicles containing syntaxin at a high protein/lipid ratio (>or=1:250) lost membrane integ

230 ging rates of pollen from plant species with high protein:lipid (P:L) ratios; the most preferred plan

231 res were found to be not ideal for obtaining high protein loading (>2% w/w of LYZ).

232 obilized CAT retained its bioactivity with a high protein loading of 4.072 x 10(-10) mol cm(-2), thus

233 o-layer" structure for ultra low fouling and high protein loading properties was developed.

234 tion of the subunits can be observed even in high-protein loads (up to 40microg of protein).

235 Results showed that these species contain high protein, low cholesterol and energy levels, being i

236 er, appetite, and weight-loss responses to a high-protein, low-carbohydrate [(LC) ketogenic] and thos

237 Derived from these outcomes, high-protein, low-carbohydrate diets are also being exam

238 High-protein, low-carbohydrate diets have also been inve

239 High-protein, low-carbohydrate diets have been found to

240 In the short term, high-protein, low-carbohydrate ketogenic diets reduce hu

241 that compared energy-restricted, isocaloric, high-protein, low-fat (HP) diets with standard-protein,

242 he basis of our previous data, we designed a high-protein/low-carbohydrate, weight-maintaining, nonke

243 ine, in an amount likely to be ingested in a high-protein meal, does not stimulate insulin secretion

244 ief periods of fasting or the ingestion of a high-protein meal.

245 t redistributing total protein intake from 1 high-protein meal/d to multiple moderately high-protein

246 and susceptibility to hypoglycemia following high protein meals.

247 1 high-protein meal/d to multiple moderately high-protein meals improves 24-h muscle protein synthesi

248 carbohydrate [(LC) ketogenic] and those to a high-protein, medium-carbohydrate [(MC) nonketogenic] di

249 lower food intake significantly more than do high-protein, medium-carbohydrate nonketogenic diets.

250 ein (NP; 14% of energy from protein), medium-high protein (MHP; 25% of energy from protein), and high

251 using proteins for biorefineries, for which high-protein microalgae could be used as a feedstock wit

252 The effect of enteral high-protein, mixed-nutrient load on tracer-determined v

253 s that this region in the beta subunit has a high protein mobility with a low energy barrier to trans

254 al samples from obese volunteers following a high-protein moderate carbohydrate weight-loss diet, com

255 lysis of the protease) can be severe, due to high protein molecular weight(s) and the broad isotopic

256 eage priming and proposes the need of either high protein numbers or long-term modifications such as

257 rmediate-moisture food (IMF) market, such as high protein nutrition bars (HPNB), has significantly in

258 er individuals fared better when maintaining high-protein nutritional plane.

259 meals (i.e., high carbohydrate, high fat, or high protein) on separate days in a random order, which

260 Thus, the Gcdh-/- mouse exposed to high protein or lysine may be a useful model of human GA

261 oped technique for dilution of the naturally high protein packing density in isolated grana membranes

262 Promotion of high-protein, palatable eudicots or increasing the prote

263 lar organisms and rapidly growing cells with high protein production have short NRL ranging from 160

264 ides a relevant concentration for a range of high-protein products.

265 is an intracellular adaptor molecule with a high protein-protein interaction capacity.

266 n of a variety of proinflammatory cytokines, high-protein pulmonary edema, and neutrophilic lung infl

267 ng profiles of extracts was evidenced, where high protein recovery levels did not always correlate wi

268 CAX-PAGE provides high protein resolving power with a theoretical peak cap

269 ddition, AFM images of ORF1p bound to RNA at high protein/RNA molar ratios show that ORF1p can form t

270 ules under tensional loading, albeit only at high protein:RNA ratios.

271 r sustainable food production, especially of high-protein seed.

272 -30 A away from the methyl group, indicating high protein sensitivity and plasticity to DNA modificat

273 The results show that high protein sequence coverages (>80%) can be obtained f

274 Despite high protein sequence similarity and partially overlappi

275 High protein sequence similarity correlated inversely wi

276 anel of recombinant CAP256 gp120s displaying high protein sequence variability and changes in PNGS nu

277 stically with MSG when tasted, is present in high-protein sources, and may potentially further enhanc

278 We find that RBPs generally exhibit high protein stability, translational efficiency, and pr

279 Taken together, these factors contribute to high protein stability.

280 , striatum) in a low-protein state than in a high-protein state.

281 e in the ad libitum phase as compared with a high-protein state.

282 fect of a low protein status compared with a high protein status on food intake and food preferences.

283 The Western diet is characterized by high protein, sugar, fat, and low fiber intake, and is w

284 toichiometry complexes, even in the limit of high [protein], suggests that the 2:2 species represents

285 L of breast milk [n = 15]) or individualized high-protein supplementation based on protein and fat co

286 iple myeloma (MM) cells are characterized by high protein synthesis resulting in chronic endoplasmic

287 Pancreatic acinar cells possess very high protein synthetic rates as they need to produce and

288 that Smc2/4-DNA-bound species formed at even high protein to DNA mole ratios remain reversible.

289 nerally nutrient dense, whereas insects with high protein-to-fat ratios were eaten by nonhuman primat

290 scs carrying an inserted receptor dimer have high protein-to-lipid ratios approximating native membra

291 most likely due to the exocrine function and high protein turnover within the pancreas.

292 at ETHE1 has a key function in situations of high protein turnover, such as seed production and the u

293 pid proliferation of cancer cells mandates a high protein turnover.

294 e low-grade B-cell lymphoma characterized by high protein turnover.

295 hagy-lysosomal degradation, accompanied by a high-protein-turnover state.

296 sess appetite response to meat or vegetarian high-protein weight-loss (HPWL) diets in obese men to mo

297 It is unclear whether low-carbohydrate, high-protein, weight-loss diets benefit body mass and co

298 (low protein), 15% (normal protein), or 25% (high protein), which they were overfed during the last 8

299 These reagents are renewable and have high protein yields (~20-25mg/L), when expressed in Esch

300 on coopts the host cell machinery to provide high protein yields of industrial enzymes or biotherapeu