ライフサイエンスコーパス: high-risk group

1 cer or AEH cases were identified within this high risk group.

2 78 (2.59-23.36, P = 0.0003) in the metabolic high risk group.

3 hasis of existing weight guidelines for this high-risk group.

4 tatic tumors has not been documented in this high-risk group.

5 odel accuracy to 0.81 (9.5%, P<0.001) in the high-risk group.

6 pranolol is the least effective drug in this high-risk group.

7 so provide novel targets for therapy in this high-risk group.

8 activated NF-kappaB pathway association with high-risk group.

9 providing several potential benefits in this high-risk group.

10 educe stroke morbidity and mortality in this high-risk group.

11 f T2D in 12,535 Indians, a less explored but high-risk group.

12 verage by race/ethnicity within each age and high-risk group.

13 large nodules (>/=3 cm) were assigned to the high-risk group.

14 as split point, assigning 13 patients into a high-risk group.

15 P = .008) and primarily confined to the non-high-risk group.

16 ied patients with molecular failure as a new high-risk group.

17 or calcium and vitamin D supplements in this high-risk group.

18 Adverse events are uncommon, even in this high-risk group.

19 f recent improved treatment extended to this high-risk group.

20 lation, they remain alarmingly high for this high-risk group.

21 ients, with black women being a particularly high-risk group.

22 mutations, 91% were in the CN-AML molecular high-risk group.

23 fect of the two loci is still greater in the high-risk group.

24 e and reduced acute care utilization among a high-risk group.

25 atic cancer susceptibility gene are one such high-risk group.

26 , we must address the burden of LTBI in this high-risk group.

27 hose with pure amnestic MCI, constituted the high-risk group.

28 ive practices in providing services for this high-risk group.

29 may improve the long-term prognosis of this high-risk group.

30 after diagnosis to advance research in this high-risk group.

31 h sodium reduction and the DASH diet in this high-risk group.

32 interventions to reduce cancer risk in this high-risk group.

33 ve intervention for preventing falls in this high-risk group.

34 with no apparent bleeding liability in this high-risk group.

35 made up the low-risk group; all others, the high-risk group.

36 and new approaches are needed for this very-high-risk group.

37 a low CFH risk score improved more than the high-risk group.

38 aining 73040 women and 34608 men made up the high-risk group.

39 e of prevention and control measures in this high-risk group.

40 tients with low-grade dysplasia to a low- or high-risk group.

41 lternative interventional procedures in this high-risk group.

42 ta applicable to this frequently encountered high-risk group.

43 14.4 % in the low-risk group to 56.2% in the high-risk group.

44 t did not increase prescription rates in the high-risk group.

45 n in cortical surface area compared with the high-risk group.

46 more units screening patients for MRSA from high risk groups.

47 ediate) risk group, and score 4 to 5 as 'C' (high) risk group.

48 eemerging epidemic of HDV infection in these high-risk groups.

49 rapy should be granted for patients in these high-risk groups.

50 ther statins have chemopreventive effects in high-risk groups.

51 tion of infectiousness, and the existence of high-risk groups.

52 ion, but there are no data about patients in high-risk groups.

53 dults, although the uptake was suboptimal in high-risk groups.

54 and used to classify patients into low- and high-risk groups.

55 forecast the progression of periodontitis in high-risk groups.

56 stimated the risk of death at 1 year for the high-risk groups.

57 thus, absolute benefits were greatest in the high-risk groups.

58 general and targeted initiatives focused on high-risk groups.

59 ay be highly cost effective when targeted at high-risk groups.

60 Biomarkers may identify high-risk groups.

61 ge-scale prevention interventions focused on high-risk groups.

62 owed significant divergence between low- and high-risk groups.

63 risk for subsequent stroke may exceed 20% in high-risk groups.

64 ), which is presumed to allow reinfection of high-risk groups.

65 ve pulmonary disease (COPD), particularly in high-risk groups.

66 nutritional biomarkers also differs in these high-risk groups.

67 statistically distinct low-, moderate-, and high-risk groups.

68 risk for the onset of EDs, at least in some high-risk groups.

69 t study to show that EDs can be prevented in high-risk groups.

70 take of STI testing for all groups including high-risk groups.

71 specificity (87.1-100%) in both healthy and high-risk groups.

72 to target lung-cancer prevention measures to high-risk groups.

73 r individual carcinomas between the low- and high-risk groups.

74 ified patients into low-, intermediate-, and high-risk groups.

75 fatty liver disease (NAFLD) is worthwhile in high-risk groups.

76 ationale for future preventive strategies in high-risk groups.

77 us across both time points was found in both high-risk groups.

78 Universal HIV testing may be mandatory in high-risk groups.

79 tient and to form low-risk, medium-risk, and high-risk groups.

80 he APOL1 low-risk group (hazard ratio in the high-risk group, 1.88; P<0.001).

81 , the intermediate-risk group (41%), and the high-risk group (12%) showed 2-year rates of CNS disease

82 progression-free survival was shorter in the high-risk group (18.5 vs 36.5 months, P < .001), but ove

83 validation cohort, m7-FLIPI again defined a high-risk group (22%, 24/107) with 5-year failure-free s

84 In the training cohort, m7-FLIPI defined a high-risk group (28%, 43/151) with 5-year failure-free s

85 In the high-risk group, 3 of 21 eyes that underwent LPI (14.3%)

86 There was increased mortality in the high-risk group (5.5% compared with 2.5%) due to unnatur

87 ), stage T3c, 18% versus 64% (P = .001), and high-risk group (50% v 72%; P = .05).

88 There were 1,018 patients in the high-risk group (50.8% eptifibatide, 49.2% placebo) and

89 In the high-risk group, 75% of patients were accurately predict

90 ight high-grade dysplasia cases, whereas the high-risk group (8% of the cohort) had no non-dysplastic

91 um consumption was 944 (846, 1043) mg in the high-risk group, 821 (788, 854) mg in the moderate-risk

92 V infection is significant, especially among high-risk groups (adjusted odds ratio, 2.0-3.6), when ta

93 ctin-3 with new-onset HF was stronger in the high-risk group (all P<0.05).

94 strategies and the management of cases, and high risk groups and regions should be targeted.

95 ts and 7.99% of eptifibatide patients in the high-risk group and 9.02% of the placebo and 8.11% of ep

96 ammes should recognise men as an underserved high-risk group and improve men's access to diagnostic a

97 curred in 58.1% of the patients in the APOL1 high-risk group and in 36.6% of those in the APOL1 low-r

98 For the high-risk group and its subcategories, the ICER was very

99 result in improved herd immunity in both the high-risk group and the population as whole.

100 CV was 11.87% (95% CI 7.05-16.70) across all high-risk groups and 9.95% (6.79-13.11) in patients with

101 and HIV-infected individuals have emerged as high-risk groups and a reservoir for HDV infection.

102 Interventions should target these high-risk groups and be of sufficient quality to make th

103 Cutoff values define low- and high-risk groups and improve risk prediction of GRACE sc

104 s not declining; more careful prescribing to high-risk groups and improved monitoring of serum levels

105 o suicide prevention include those targeting high-risk groups and population strategies.

106 uberculosis transmission must be targeted to high-risk groups and settings.

107 a mathematical model of HIV transmission in high-risk groups and the general population using data f

108 offspring of parents with major depression (high-risk group) and 22 offspring of parents without his

109 features or more than three seizures as the high-risk group, and those with a single seizure only as

110 otoxic treatments should be reconsidered for high-risk groups, and frequent follow-up for high-risk s

111 w that mutations occur infrequently in these high-risk groups, and that they occur mainly in exons 1a

112 man breast cancer patients into low-risk and high-risk groups, and to predict their risk of early dis

113 OR [AOR] 1.2; 95% CI, .4-3.3) but not in the high-risk group (AOR .4; 95% CI, .3-.5).

114 Screening high-risk groups appears effective, although general pop

115 management of pregnancy and delivery in this high-risk group are lacking.

116 nd why certain individuals within recognized high-risk groups are at greater risks than others for co

117 Prevention strategies targeted at high-risk groups are promising.

118 ts were assigned to mild-, intermediate-, or high-risk groups based on cutoff values for 2 of the fol

119 When categorized into low-, moderate-, and high-risk groups based on risk alleles, we found the per

120 (SAMS) to classify patients into low-risk or high-risk groups based on the 52-gene signature.

121 VEF < or =0.40, MTWA can identify not only a high-risk group, but also a low-risk group unlikely to b

122 iasis in patients with neutropenia and other high-risk groups, but its use in unselected patients wit

123 ta show significantly lower survival in this high-risk group compared to patients transplanted withou

124 l was only significantly associated with the high-risk group compared with the low-risk group.

125 as comparably impaired in the CHR and family high-risk groups compared with controls, but profiles di

126 transplantation in the intermediate-risk and high-risk groups compared with the low-risk group were 4

127 -related events in the intermediate-risk and high-risk groups, compared with the low-risk group, were

128 statistically distinct low-, moderate-, and high-risk groups, corresponding to cumulative incidences

129 If such a high risk group could be identified, they may benefit fr

130 Targeting of this high-risk group could reduce the financial, medical and

131 astasis developed in 0% (0/15) of those with high-risk group D retinoblastoma and 10% (10/102) of tho

132 ng-term outcome was further evaluated in the high-risk group (D+/R-).

133 consistent between sexes and after excluding high-risk groups (defined by age and occurrence of previ

134 ; 95% CI, 0.492-1.240), and in the "expanded high-risk" group, defined as those with high-risk cytoge

135 s the efficacy of therapy, CAC evaluation of high-risk groups (diabetes and other disease states char

136 Within the high-risk group, differences in surface area at baseline

137 nts with 0 to 2 (low-risk group) and 5 to 7 (high-risk group) dosage-altered genes experienced 49.24

138 Pregnant women are a high-risk group during influenza pandemics.

139 etinoblastoma and 10% (10/102) of those with high-risk group E retinoblastoma over a mean follow-up p

140 NSCLC patients identified as high-risk groups exhibited >5 CTCs/15 mL in PPB and >50

141 orn LGA may be identified early in life as a high-risk group for asthma.

142 n whether kidney transplant recipients are a high-risk group for fracture.

143 Injecting drug users are a high-risk group for hepatitis B virus (HBV) infection an

144 Heroin addicts are a high-risk group for hepatitis C virus (HCV) infection an

145 carcinoma, which may allow us to identify a high-risk group for hepatocellular carcinoma among patie

146 patients in the discovery set into a low- or high-risk group for PFS (hazard ratio [HR], 2.43; P = .0

147 offspring of depressed parents constitute a high-risk group for psychiatric and medical problems, wh

148 Children <3-months old were a high-risk group for severe pneumonia, independently of R

149 , HIV-1 infected individuals may represent a high-risk group for XMRV infection and spread.

150 implemented as a pretesting tool to identify high-risk groups for broad monitoring of HPV-associated

151 n (0-19 years) and seniors (65+ years) after high-risk groups for influenza vaccination during times

152 mmend prioritizing seniors (65+ years) after high-risk groups for influenza vaccination during times

153 tion tree analysis was performed to identify high-risk groups for LN positivity.

154 ly useful and may also assist in identifying high-risk groups for melanoma prevention strategies.

155 more marked in patients in the moderate- and high-risk groups for stroke according to the CHADS(2) ri

156 hat heighten risk, and that we better define high-risk groups for targeted preventive and interventio

157 longer duration of antibiotics, appear to be high-risk groups for unplanned, all-cause 30-day readmis

158 Stratification into a low (0/1 point) and high-risk group (>/=2 points) resulted in significantly

159 atelet ratio index and FIB-4 score, only the high-risk group had a greater risk of death or liver tra

160 the CRIC study, black patients in the APOL1 high-risk group had a more rapid decline in the eGFR and

161 the low-risk group, those in the medium- and high-risk group had a significantly increased risk of re

162 Importantly, patients in the high-risk group had a significantly reduced overall surv

163 Patients in the high-risk group had the greatest benefit of ribavirin-ba

164 Several high-risk groups had more favorable ICERs, including pat

165 The high-risk groups had more than a 2-fold increased risk o

166 clinicopathologic parameters shows that the high-risk group has significantly reduced survival on bo

167 The addition of MRI to mammography in the high-risk group has the greatest potential to detect add

168 low-risk groups and low-risk patients within high-risk groups has the potential to affect therapeutic

169 In contrast, those in the high-risk group have a > 10% risk of CNS relapse and sho

170 rmediate group, and 22.2% (15.3-31.5) in the high-risk group having distant recurrence.

171 [HR], 0.84; 95% CI, 0.80-0.88; P < .001) and high-risk groups (HR, 0.82; 95% CI, 0.78-0.85; P < .001)

172 mediate-2 (HR, 4.9; 95% CI, 3.2 to 7.7), and high-risk groups (HR, 10.7; 95% CI, 6.8 to 16.9), respec

173 ctions suggests that targeting prevention to high-risk groups (HRG) could be very effective.

174 Users of MHT may constitute an additional high-risk group in need of more frequent skin cancer scr

175 ncreas transplantation and clearly defines a high-risk group in need of specific intervention.

176 sidered for clinical use, identifying a very high-risk group in whom liver biopsy would be very likel

177 1.7% of the sample) represent a particularly high-risk group in whom the risk for renal scarring was

178 n to vulnerable, RSV-naive infants and other high risk groups, in which the burden of admission to ho

179 The high-risk group included in the trial comprised asymptom

180 enters that conduct prospective screening in high-risk groups including families with clustering of P

181 ted with rhEPO administration, especially in high-risk groups, including polycythemia-hyperviscosity

182 uggest that novel vaccination strategies for high-risk groups, including the obese population, are re

183 e evaluated enhanced HIV testing (annual for high-risk groups), increased 3-month linkage to care (to

184 into leukemogenesis of the CN-AML molecular high-risk group, indicating that CEBPA mutations are ass

185 of the risk of asthma exacerbations in this high-risk group is attributable to a genetic risk factor

186 Long-term maintenance care for high-risk groups is essential to reduce the risk of peri

187 tanding of the developmental trajectories of high-risk groups is still needed.

188 vaccination for healthcare workers and other high-risk groups is the mainstay of the public health st

189 that met three or fewer conditions formed a high-risk group (log-rank P < .0001).

190 Patients in the metabolic high-risk group (low TSP and weight loss) had an increas

191 absence for a substantial time, and even in high-risk groups, many were not on sickness absence or d

192 Interventions targeting this high-risk group may decrease frequent hospital readmissi

193 d children, depression prevention methods in high-risk groups may need to take into consideration soc

194 Screening high-risk groups may reveal a higher prevalence than see

195 Surveillance of high-risk groups, may facilitate detection of PDAC at an

196 In low-, moderate-, and high-risk groups, mean LDL-C was 119, 109, and 91 mg/dL

197 Patients in high-risk groups might be managed more aggressively and

198 ections for short-term CVCs, particularly in high-risk groups; more research is needed.

199 IV infection (n = 939), 5.2% of those in the high-risk group (n = 1,003), and 0.1% of those in the lo

200 Score, 5.9%) and 206 (12.2%) subjects in the high-risk group (n=1654; Framingham Risk Score, 18.6%).

201 ear kidney allograft survival rates of 6.0% (high-risk group, n=40), 44.9% (intermediate-risk group,

202 r strategies for long-term treatment of this high-risk group need to be identified.

203 This review identified a possible high-risk group (nonresponse), which proved radioresista

204 h for the first time identified a clinically high-risk group of AML that may particularly benefit fro

205 with a restrictive transfusion strategy in a high-risk group of elderly patients with underlying card

206 linical score, serosurveillance in a defined high-risk group of extracorporeal membrane oxygenator pa

207 ral nutrition safely and effectively to this high-risk group of infants.

208 Finally, in the ALSPAC high-risk group of male participants, those who used can

209 risk factors cannot identify a sufficiently high-risk group of outpatients for thromboprophylaxis.

210 The high-risk group of patients had a shorter median TFS (22

211 urthermore, mutational analysis identified a high-risk group of patients with a shorter time to disea

212 The greatest effects were evident in the high-risk group of patients with all KIR ligands (relaps

213 Statistical models identified a homogeneous high-risk group of patients with lesions > or = 4 cm, pe

214 ood response rates in this highly pretreated high-risk group of patients, there was no benefit in sur

215 risk prediction and therapeutic targets for high-risk groups of patients and offenders.

216 ogically based assessments can also identify high-risk groups of patients.

217 d on risk of death and return on investment, high-risk groups of the three age group subpopulations c

218 ed into clinical standard, intermediate, and high risk groups on the basis of a combination of Nation

219 ion (n = 17); and 3) subjects matched to the high-risk group on personal drug use but without a FH of

220 inical standard-risk, intermediate-risk, and high-risk groups on the basis of a combination of Nation

221 causes fulminant hepatic failure in specific high-risk groups only.

222 Vaccine-delivery strategies that target high-risk groups or settings might yield proportionally

223 2 copies of high-risk APOL1 variants (APOL1 high-risk group) or 0 or 1 copy (APOL1 low-risk group).

224 by subgroup for excess prematurity risk, the high-risk group (overall prematurity of 22.2% to 62.8%)

225 re < 5%, compared with approximately 20% for high-risk groups ( P < .001); cumulative incidence was o

226 e-risk group and 70% (54-84) in those in the high-risk group (p=0.04); 5-year event-free survival was

227 n users was seen in low-, intermediate-, and high-risk groups (P = .0401, P = .0331, and P = .0034, r

228 strains of cannabis on risk, and to identify high-risk groups particularly susceptible to the effects

229 ork might help reduce HIV prevalence in this high-risk group, particularly in countries where the jud

230 Comparisons were made between high-risk group patients (PN) versus all others: 5-year

231 After three blocks of therapy, all high-risk group patients and those from the intermediate

232 High-risk group patients and those that remain RT-PCR po

233 g criterion for localized PC that identifies high-risk group patients with clinically relevant occult

234 In this biologically high-risk group, pCR differs by receptor subset.

235 irmed ccRCC and fell into 1 of the following high-risk groups: pT3/pT4Nx/N0M0 or pTanyN+M0 or pT1b/pT

236 stents versus bare metal stents in specific high-risk groups require further study.

237 BWH T2b/T3 tumors define a high-risk group requiring further study for optimal mana

238 nd 9.0 months for lower-, intermediate-, and high-risk groups, respectively (P < .001).

239 %, and 87.5% in the low-, intermediate-, and high-risk groups, respectively.

240 y were 12% and 42% higher in the medium- and high-risk groups, respectively.

241 the medium (risk score 0-4, 103 events) and high risk groups (risk score >/= 5, 505 events), respect

242 uction of mortality in the intermediate- and high-risk groups (risk ratio, 0.84; 95% CI, 0.77-0.92 an

243 grams using an ECG and targeting 2 potential high-risk groups: school-aged children initiating stimul

244 .0), and 39.1% (95% CI: 19.7%, 61.5%) in the high-risk group (score > 8.0).

245 sk categories, and the gaps between low- and high-risk groups seem to be narrowing.

246 ion of empiric antimicrobial therapy in this high-risk group should be restructured.

247 creening of pregnant and postpartum women in high-risk groups should be evaluated.

248 ower than the control group, while the ultra-high-risk group showed a trend toward the early group.

249 The ultra-high-risk group showed significantly smaller differentia

250 en of disease now disproportionately affects high-risk groups such as migrants, homeless persons, and

251 tion with a high mortality rate that affects high-risk groups such as patients with neutropenia and h

252 Systematic application of FRAX to screen high-risk groups such as patients with RA may be used to

253 e target for preventing colorectal cancer in high-risk groups such as those with familial adenomatosi

254 Programmes focused on high-risk groups, such as individuals leaving prisons, p

255 zation of race or ethnicity did not identify high-risk groups, such as persons of Asian and Pacific I

256 treatment, and increasing testing frequency, high-risk-group testing, and adherence.

257 These patients represent a high risk group that may benefit from integrated therapy

258 nction in school age children may identify a high-risk group that could be targeted for intervention.

259 ne a pathogenesis for type 2 diabetes in one high-risk group that is characterized by a relatively lo

260 are classified into low-, intermediate-, and high-risk groups that reflect relative survival categori

261 istory of the disease to accurately identify high-risk groups that would be best served by screening.

262 In this high-risk group, the emergence of new viral strains foll

263 In the Thymoglobulin high-risk group, the transcriptome profile was identical

264 rent outcomes, particularly in the molecular high-risk group, thus improving molecular risk-based cla

265 AIMS: To engage with high risk groups to identify knowledge and awareness of

266 shifting vaccination resources away from the high-risk group to the high-activity group will result i

267 for prospective and longitudinal studies in high-risk groups to clarify how changes in sleep physiol

268 ast cancer prevention, should be targeted to high-risk groups to maintain a favourable benefit-risk r

269 factors), with 5-year survival of 44%, and a high-risk group (two to five factors), with 5-year survi

270 ere stratified into low-, intermediate-, and high-risk groups using the Framingham risk score.

271 Identification of high-risk groups using this index would distinguish pati

272 edictive value for cirrhosis was >66% in the high-risk group vs approximately 50% in the low-risk gro

273 The median overall survival for the GEP70 high-risk group was 19 months versus not reached for the

274 Morbidity in this high-risk group was equally low: 1 of 47 (2%) patients u

275 The early onset of disorder seen in the high-risk group was not offset by a later onset in the l

276 in-hospital mortality for low-, medium-, and high-risk groups was 8%, 7%, and 16%, respectively, for

277 del for OS separating patients into low- and high-risk groups was produced using penalized Cox regres

278 An immunization campaign targeting high-risk groups was undertaken with pneumococcal polysa

279 The corresponding odds ratios for the high-risk group were 0.79 (0.55-1.13 [n=3561]), 0.75 (0.

280 e increased rates of major depression in the high-risk group were largely accounted for by the early

281 e early onsets, but later recurrences in the high-risk group were significantly increased.

282 ar EFS rates in the low-, intermediate-, and high-risk groups were 70%, 56%, and 29%, respectively.

283 year OS rates in MIPI low, intermediate, and high-risk groups were 83%, 63%, and 34%, respectively.

284 Using this score, low-, medium-, and high-risk groups were defined, with predicted survival a

285 Two high-risk groups were identified: men and women with der

286 berculosis in the low-risk, medium-risk, and high-risk groups were, respectively, 1.4% (95% CI 0.7-2.

287 berculosis in the low-risk, medium-risk, and high-risk groups were, respectively, 2.8% (95% CI 1.7-4.

288 activation than RISK+ subjects) and the SCZ high-risk group, where the opposite genotype effect was

289 DGKH gene in healthy controls vs the bipolar high-risk group, which manifests as a failure to disenga

290 early recurrences of VT after ablation are a high risk group who may be identifiable from their clini

291 Smokers aged >/= 65-80 y are a high-risk group who may benefit from screening.

292 In the healthy controls and high-risk group who remained well, this region demonstra

293 Dual expresser status may help to identify a high-risk group who should undergo CNS-directed evaluati

294 is only likely to be cost-effective for very high-risk groups who may be exposed to multiple exposure

295 nths (median survival was not reached) and a high-risk group with a median survival of 7.8 months (95

296 -fold (0.92-1.81) increased risk whereas the high-risk group with more than two unfavorable genotypes

297 Community-based screening of high-risk groups with functional testing using FDT perim

298 re stratified the patients into low-risk and high-risk groups with significant survival difference.

299 ed mortality, morbidity, and expense in this high-risk group, with decreased longevity, present a gro

300 ficantly shorter MICU length of stay in this high-risk group without any significant differences in m