ライフサイエンスコーパス: high-throughput

1 high-speed, large-area, high-resolution and high-throughput.

2 ial community structure was characterized by high-throughput 16 s rRNA gene amplicon sequencing.

3 n estimate of net community production, with high-throughput 18 S ribosomal DNA sequencing to elucida

4 Thanks to the high throughput acquisition of biomarker levels in G. fo

5 eer stable, active enzymes without laborious high-throughput activity screens.

6 provides a foundation for the development of high throughput acyclical classifiers and hierarchical s

7 The proposed mutants were tested in a second high-throughput AFM SMFS experiment revealing that in on

8 High-throughput amplicon sequencing of environmental DNA

9 usly, the MHC region has been intractable to high-throughput analysis at complete sequence resolution

10 This high-throughput analysis detected Ag-specific human T ce

11 he use of ethoscopes, which are machines for high-throughput analysis of behavior in Drosophila and o

12 To permit high-throughput analysis of gene networks, we have imple

13 dentification due to a lack of tools for the high-throughput analysis of RNA-RNA interactions in bact

14 the FDL-based approach enabled sensitive and high-throughput analysis of the enzymatic hydrolysis of

15 is compatible with laboratory automation for high-throughput analysis.

16 This work reports a high throughput and label-free microfluidic cell deforma

17 To meet high throughput and rapid turnaround time requirements,

18 adherent cells at multiple frequencies with high throughput and will provide valuable clues in under

19 ed by literature data and were obtained in a high-throughput and automated manner.

20 This enables high-throughput and automated single-cell microscopy for

21 refore, there is an urgent need to develop a high-throughput and efficient strategy to identify the E

22 ion trap mass spectrometer was designed for high-throughput and rapid mass analysis of large biopart

23 With the goal to develop high-throughput and robust quantitative methods for the

24 Here, we adopt a label-free, high-throughput, and continuous technique utilizing iner

25 is compatible with high-content imaging and high-throughput applications.

26 rendering these experiments ineffective for high-throughput applications.

27 ribed here provides a technically simple yet high-throughput approach for generating a collection of

28 Using this high-throughput approach, we defined three sets of chrom

29 These high-throughput approaches offer investigators a toolkit

30 Our device allows high-throughput approaches, patterning different cell ty

31 High-throughput assays for measuring the three-dimension

32 High-throughput assays that produce hundreds of measurem

33 developmental toxicity compared to BDE 47 in high-throughput assays.

34 ighted sequences increasingly available from high-throughput assays.

35 om a single specimen and can be applied to a high-throughput automated platform.

36 hnology opens the possibility to combine the high-throughput biochemical or living cell screenings us

37 High-throughput biology presents unique opportunities an

38 ds much promise for real-time, accurate, and high throughput biosensing.

39 The LOC platform would be widely used as a high-throughput biosensor to analyze food, clinical and

40 ze and cytoplasmic and nuclear morphology in high throughput, but only the final cell counts are comm

41 We used high-throughput calcium-flux assays and patch clamp reco

42 Based on the high-throughput calculation, a sandwich microstructure f

43 ly benefit from low reagents consumption and high throughput capacity of droplet-based microfluidic s

44 Thus, we designed a high-throughput chemical screen platform to quantify PGC

45 Here, we use high-throughput coarse-grained molecular dynamics simula

46 Here, we demonstrate a high-throughput communication approach using the orbital

47 his shortcoming, we have developed a robust, high-throughput compatible, click chemistry-based approa

48 h target properties, such as auxetics, using high-throughput computations, open databases, and effici

49 n automated Web service running on community high-throughput computing and distributed data storage i

50 tivity concentrations (AWBCs) generated from high throughput data as a health-based screen for endocr

51 wing interactive exploration and analysis of high throughput data.

52 scussions regarding the potential synergy of high-throughput data acquisition, data-driven modeling,

53 greatly facilitated neuroscience research in high-throughput data acquisition.

54 ontrol samples (iii) filter large amounts of high-throughput data based on user custom filter require

55 s fast and user-friendly network analysis of high-throughput data by mapping the data onto a biologic

56 technological developments a vast amount of high-throughput data has been profiled to understand the

57 this study, we employed the next generation high-throughput deep sequencing technology to sequence a

58 As can be identified by analyzing reads from high-throughput deep sequencing.

59 The high-throughput detection of organelle composition and p

60 Here we report a method for the high-throughput determination of extracellular segments

61 We present an approach to multidimensional high-throughput discovery of catalytic coupling reaction

62 and paving the way for a broadly applicable high-throughput-discovery and materials-by-design feedba

63 -control studies of MDD: the GlaxoSmithKline-High-Throughput Disease-specific target Identification P

64 High throughput DNA sequencing (HTS) technologies genera

65 The advent of high-throughput DNA methylation profiling techniques has

66 High-throughput DNA sequencing modalities, including sin

67 High-throughput DNA sequencing of microbiota from a dive

68 With the development of new high-throughput DNA sequencing technologies and decreasi

69 With the advent of next generation high-throughput DNA sequencing technologies, omics exper

70 cell viability has been developed towards a high throughput drug screening.

71 rk to integrate drug structural information, high-throughput drug perturbation, and drug sensitivity

72 The dimensional transition enabled by a high throughput electrohydrodynamic process provides hig

73 ethods to be widely applicable to supplement high-throughput experimental antibody sequencing workflo

74 Recently developed high-throughput experimental methods, including protein

75 may have applications for certain classes of high-throughput experiments and the analysis of noisy da

76 This work may set the stage for non-invasive high-throughput experiments evaluating sleep and breathi

77 ed by introducing cost-effective, rapid, and high-throughput fabrication techniques and low-cost reco

78 A simple, high-throughput flow cytometric assay was developed that

79 nce of this work is the demonstration of how high-throughput fluorescence lifetime measurements corre

80 or the development of an array platform with high-throughput for CEA together with other tumor biomar

81 t has been assumed that miniaturisation to a high-throughput format would not be possible without con

82 a-deep transposon insertion site recovery in high-throughput formats within 1 week.

83 ated with F508del-CFTR processing, we used a high-throughput functional assay to screen an siRNA libr

84 In this study, we performed a high-throughput genetic screen to identify kinases that

85 tochondrial homeostasis and lipid metabolism.High-throughput genetic screens in animals could benefit

86 Using high-throughput genetics, 5560 minigene molecules were a

87 Although recent high-throughput genome-wide mapping approaches have allo

88 Our high-throughput genome-wide siRNA screen identified host

89 High-throughput genomic and molecular profiling of tumor

90 The increasing volume and complexity of high-throughput genomic data make analysis and prioritiz

91 Multiple types of high throughput genomics data create a potential opportu

92 The development and application of high-throughput genomics technologies has resulted in ma

93 To facilitate high-throughput genotyping of Arachis species, 20 genoty

94 CRISPR/Cas9 gene editing with an innovative high-throughput genotyping pipeline utilizing KASP (Komp

95 Due to a lack of high throughput glycan sequencing software, glycan spect

96 A high-throughput H2 production assay device (H2 PAD) is p

97 nology that is highly sensitive, robust, and high-throughput has the potential to improve patient car

98 zation resulting from the application of new high-throughput, high-content cytometry and sequencing t

99 lial cell types possesses the capacity to be high-throughput, highly reproducible and integrate the c

100 The high-throughput (HT) approach we present can be readily

101 Thus, the high-throughput (HT)-CBS technology was used for the con

102 idHunter, a new open source software for the high-throughput identification of phospholipids in data

103 High-throughput imaging (HTI) is a powerful tool in the

104 High-throughput imaging and analysis of large DNA single

105 High-throughput immunological testing of such lymphocyte

106 Here we have combined high-throughput immunophenotypic screens with large-scal

107 plicity, speed, wider compound coverage, and high-throughput in comparison to the LC-MS based approac

108 erpret (clinical science) the vast amount of high-throughput information that existing technology pro

109 the clonality of HIV-1-infected cells using high-throughput integration site analysis in a hematopoi

110 Techniques have been developed to conduct high-throughput large-scale phenotyping on animals, plan

111 inate the impact of matrix effects, even for high-throughput LC-MS methods.

112 KEY MESSAGE: Exploration with high throughput leaf metabolomics along with functional

113 Optical analog computing offers high-throughput low-power-consumption operation for spec

114 MALDI-HDX approach can also be applied in a high-throughput manner for batch-to-batch higher-order s

115 r possible therapeutics in a mechanistic and high-throughput manner.

116 ulatory networks in a modular, parallel, and high-throughput manner.

117 Here, using high-throughput marker gene sequencing of soils collecte

118 ge Cardinal for analysis of high-resolution, high-throughput mass spectrometry imaging experiments.

119 e stochastic nature of the process precludes high-throughput measurement (and sorting) of single cell

120 ities as a foundation for massive scaling in high-throughput measurements and new insights into the i

121 High throughput metabolite screening of cerebrospinal fl

122 n challenging when using culture-independent high-throughput metagenomics.

123 ial (i.e. BP) and further validates a rapid, high-throughput method for immunoproteomic antigen ident

124 Here, we describe a high-throughput method for rapid identification of syner

125 Using a high-throughput method, we developed a T7 phage display

126 n the western Arctic and sub-Arctic, we used high throughput methods to sequence 18S rRNA, cloned and

127 on, 16-S rRNA gene amplicon sequencing), yet high-throughput methods for assessing community structur

128 nvironment is hampered by a lack of adequate high-throughput methods for distinguishing and quantifyi

129 ation has been hindered by a lack of simple, high-throughput methods for mapping the transcriptomes o

130 High-throughput methods for screening protein-protein in

131 Here we report improved high-throughput methods for single-nucleus droplet-based

132 High-throughput methods now allow us to interrogate the

133 Hence, high-throughput methods that generate vast libraries of

134 tudies and computational identification from high-throughput methylome data.

135 Recently, the high-throughput microarray and sequencing technologies h

136 orized fluorescence microscopy combined with high-throughput microfluidic chips is a powerful method

137 l this differentiation switch, we employed a high-throughput microfluidic imaging system that allows

138 In this paper, we use a high-throughput microfluidic platform as a quantitative

139 High throughput mRNA expression profiling can be used to

140 The high-throughput multiplex assay allowed us to simultaneo

141 y comparing its predictions with outcomes of high-throughput mutagenesis experiments and measurements

142 Here, we combined high-throughput mutagenesis, functional screening, and d

143 tegy used to identify protein complexes from high-throughput network data has been to extract near-cl

144 The advent of high-throughput next generation sequencing technology ha

145 Using high-throughput next-generation sequencing techniques op

146 culating metabolic traits were quantified by high-throughput nuclear magnetic resonance metabolomics.

147 r individual dual-labeled protein samples at high throughputs or protein libraries compatible with mu

148 Filopodyan supports high-throughput phenotype characterization as well as de

149 Here, we used high-throughput phenotype data from 14,250 wildtype and

150 Even though high-throughput phenotyping platforms have been develope

151 ogy was proven robust to obtain ground-based high-throughput plant architecture parameters of sorghum

152 have been active research efforts to develop high-throughput platforms to mechanically characterize s

153 reproducibility, short turnaround time, and high-throughput potential of this platform demonstrate E

154 ed method, DRNApred, which accurately and in high-throughput predicts and discriminates between DNA-

155 al systems are increasingly being studied by high throughput profiling of molecular data over time.

156 proach and introduce emerging strategies for high-throughput progression from profiles to function.

157 o history of skin disease was analysed using high-throughput proteomic analysis that detects expressi

158 rdiovascular risk proteins, we used an OLINK high-throughput proteomic assay to analyze moderate-to-s

159 Using high throughput proteomics, we identified 84 candidate m

160 ssure measurement system that allows for the high-throughput quantification of gas evolution under re

161 proves to be a promising alternative for the high-throughput quantification of lignin in milled bioma

162 hether HIV antibody responses as measured by high-throughput quantitative and qualitative assays coul

163 We developed a high-throughput quantitative microarray antibody capture

164 along with automated analysis, provides for high-throughput quantitative volumetric interrogation of

165 SynAg enables the high-throughput, quantitative characterization of protei

166 all, we demonstrate that Mt/AFM-SECM enables high throughput reading of dense nanoarrays, with a sens

167 onsortium, made possible by a new, low-cost, high-throughput reduced representation expression profil

168 Nevertheless, designing high-throughput reporter assay experiments such as massi

169 th the use of reversible technologies enable high-throughput, reproducible, functional annotation of

170 strains we engineered, they can be used for high-throughput reverse genetic screens to help function

171 Illumina high throughput RNA-Seq technology was employed and gene

172 High-throughput RNA sequencing (RNA-seq) analysis of HIF

173 In the presented study we used high-throughput RNA sequencing in combination with syste

174 High-throughput RNA sequencing methods coupled with spec

175 Using a high-throughput RNA structure probing method, we provide

176 rs (WQRs) and queenless workers (WQLs) using high-throughput RNA-sequencing technology.

177 sults indicated AutoTip has applications for high-throughput sample preparation for studying the N-li

178 Cas9-mediated, high-throughput, saturating in situ mutagenesis permits

179 dentify reversible inhibitors of LSD1 from a high throughput screen and subsequent in silico modeling

180 A duplexed, functional multiaddition high throughput screen and subsequent optimization effor

181 gene-editing studies and is well-suited for high-throughput screen application.

182 We performed a high-throughput screen of 484 small-molecule compounds t

183 Here, we report a nanotechnology-enabled high-throughput screen to identify small-molecule agonis

184 Two different formats of an enzyme-based high-throughput screen yielded two attractive chemotypes

185 , the development of a cell-based, medium to high throughput screening assay that is capable of monit

186 thiazolidine-2,4-dione, was obtained from a high throughput screening of 40000 compounds against KGA

187 iques of both bacterial and host factors and high throughput screening of novel therapeutics becoming

188 We used a genetically encoded high throughput screening platform to screen a SICLOPPS

189 o extrapolation (IVIVE) analyses translating high-throughput screening (HTS) data to human relevance

190 In this study, we utilized high-throughput screening (HTS) in vitro data of PAHs to

191 rgently required, however current cell-based high-throughput screening (HTS) models to identify molec

192 In parallel, high-throughput screening (HTS) was conducted using the

193 H binding site using an ADP-TAMRA probe in a high-throughput screening assay.

194 tion, and has immense potential for fast and high-throughput screening bacterial chemotaxis.

195 tion, we prioritized candidate compounds via high-throughput screening based on reversal of green flu

196 of false positives and false negatives under high-throughput screening conditions is particularly dif

197 bility to high-content microscopy in 96-well high-throughput screening format and validate its applic

198 High-throughput screening identified anthracyclines incl

199 escence spectroscopy could offer a rapid and high-throughput screening method for identification of L

200 s being considered for large-scale use, this high-throughput screening method will facilitate rapid s

201 In this study, using a cell-based high-throughput screening model representing Runt-relate

202 uantitative sensing technology allowed for a high-throughput screening of a panel of polymer carriers

203 omplexes opens up the possibility to perform high-throughput screening of G-quadruplex ligands for th

204 he CRISPR/Ca9s system is also being used for high-throughput screening of genes, gene regulatory regi

205 The former method is convenient for high-throughput screening of potential GLUT5 inhibitors

206 High-throughput screening of the host transcriptional re

207 rganization for fundamental studies, and for high-throughput screening of various biomolecules for st

208 f electrochemical methods for the purpose of high-throughput screening remains very limited.

209 We previously identified, by high-throughput screening, aminophenyl-1,3,5-triazine CF

210 s9 system, from efficient genome editing, to high-throughput screening, to recruitment of a range of

211 lenges that are currently encountered during high-throughput screening.

212 ombinant RSV virus and applied the strain to high-throughput screening.

213 We performed fragment-based and high-throughput screens against an amino-sugar acetyltra

214 ism of action (MoA) of hits from these noisy high-throughput screens remain difficult.

215 Utilizing high-throughput screens, we identify prion-curing mutant

216 We developed an assay for the high-throughput search for compounds that prime microbia

217 he basis of our new multiplexed protocol for high-throughput, selective RNA-sequencing called SL-seq.

218 luding protein binding microarrays (PBM) and high-throughput SELEX (HT-SELEX), have enabled rapid mea

219 This has created a need for high throughput sequence analysis directly on surfaces.

220 One of the most crucial steps in high-throughput sequence-based microbiome studies is the

221 By high throughput sequencing (HTS), we obtained the first

222 approaches (transcriptomics, proteomics and high throughput sequencing crosslinking immunoprecipitat

223 We also applied the algorithm to high throughput sequencing data obtained for viruses pre

224 CGD, which allows online browsing of mapped high throughput sequencing data, and its implementation

225 High throughput sequencing techniques are poorly adapted

226 Due to the recent advances in high throughput sequencing technologies, an increased nu

227 transposase-accessible chromatin coupled to high-throughput sequencing (ATAC-seq) data, we found tha

228 oss-Linked ImmunoPrecipitation associated to high-throughput sequencing (CLIP-seq).

229 High-throughput sequencing (HTS) and bioinformatics have

230 .) has many advantages over laboratory-based high-throughput sequencing (HTS) methods for species lev

231 ith pathogenic RASGRP2 variants, we compared high-throughput sequencing and phenotype data from 2042

232 High-throughput sequencing data are widely collected and

233 By integrating high-throughput sequencing data for binding and splicing

234 The use of high-throughput sequencing data has improved the results

235 High-throughput sequencing has made it theoretically pos

236 High-throughput sequencing in the four remaining familie

237 Here we develop a high-throughput sequencing method that enables accurate

238 High-throughput sequencing of 16SrRNA genes demonstrated

239 Most discordances were clarified upon high-throughput sequencing of antigen-receptor rearrange

240 As high-throughput sequencing of B cells becomes more commo

241 The recent high-throughput sequencing of cancer genomes and transcr

242 species by combining systemic dsx knockdown, high-throughput sequencing of diverse tissues and a geno

243 Short- and long-read high-throughput sequencing of DNA and RNA demonstrated t

244 atients and 7 healthy controls, we performed high-throughput sequencing of immunoglobulin heavy chain

245 We used high-throughput sequencing of short, cyclobutane pyrimid

246 High-throughput sequencing of TEM-1 populations shows th

247 olism in the reactor, and the Illumina MiSeq high-throughput sequencing revealed 22 phyla and 88 gene

248 High-throughput sequencing revealed that a 22 nt miRNA w

249 However, despite high-throughput sequencing studies, the cause of the dis

250 cture and compositions were determined using high-throughput sequencing targeting the V3-V4 regions o

251 Meanwhile, the advent of several high-throughput sequencing techniques for profiling init

252 along with advances in mass spectrometry and high-throughput sequencing techniques, have caused resea

253 High-throughput sequencing technologies and a suite of c

254 High-throughput sequencing technology contributed to con

255 Here, we develop a high-throughput sequencing technology to define TOP2 cle

256 Massively parallel high-throughput sequencing technology, where DNA is shea

257 use a combination of targeted enrichment and high-throughput sequencing to assemble and interpret a d

258 es, and RNA sequencing (RNA-Seq), which uses high-throughput sequencing to capture all sequences.

259 advanced in-solution mitogenome capture and high-throughput sequencing to fourteen dental samples ob

260 High-throughput sequencing was performed on 12 different

261 nt problem, particularly given the growth of high-throughput sequencing, cell sorting and single cell

262 By high-throughput sequencing, we identified the main bacte

263 ker, Tn5 tagmentation, PCR amplification and high-throughput sequencing.

264 se transcriptase PCR, microarray analysis or high-throughput sequencing.

265 saturated transposon mutagenesis coupled to high-throughput sequencing.

266 e quantification of cytosine methylation via high-throughput sequencing.

267 sition were revealed by quantitative PCR and high-throughput sequencing.

268 andscape of anaerobic infections in HS using high-throughput sequencing.

269 s now yielding to much larger data sets from high-throughput sequencing.

270 -linking and immunoprecipitation followed by high-throughput sequencing.

271 ine for developing STR markers directly from high-throughput shotgun sequencing data without a refere

272 A high-throughput single cell profiling method has been de

273 re and dynamics on alphavbeta3 binding using high-throughput single-molecule three-color Forster reso

274 High throughput size based separation and sorting of bio

275 This technique performs continuous-flow, high throughput size based sorting of millions of partic

276 We performed miRNA and mRNA profiling using high throughput stem-loop reverse-transcriptase quantita

277 findings demonstrate a previously unexplored high-throughput strategy for GSC-selective antibody disc

278 synaptic networks will require new tools for high-throughput structural and molecular profiling of th

279 er it can be used for biomarker discovery in high throughput studies is yet to be determined.

280 dividual studies with those identified in 13 high-throughput studies reveals limited consistency.

281 g and extracting single-cell data, mean that high-throughput systematic analyses of signalling dynami

282 scaling translational microbiome research to high-throughput target discovery across large population

283 ng short analysis time, make it suitable for high-throughput targeted UPLC-ESI-MS/MS metabonomic anal

284 Tn-Seq is a high throughput technique for analysis of transposon mut

285 In summary, this high-throughput technique catalogs the potential phospho

286 here are significant improvements using this high-throughput technique for the generation of mAbs inc

287 Our precise, high-throughput technique revealed stable between-host v

288 scription assays are a relatively new set of high throughput techniques that measure the location of

289 Advances in high-throughput technologies allow for measurements of m

290 High-throughput technologies have revolutionized medical

291 ary generation capacity outpaces the rate of high-throughput testing and screening.

292 Despite that many techniques are high-throughput, they usually use singular features of t

293 n the basis of calculations, once coupled to high throughput, this method can potentially yield prepa

294 110 ER and 212 AR bioactive chemicals using high throughput ToxCast data from in vitro screening ass

295 eening assays and predictive pathway models, high-throughput toxicokinetic data, and data-driven assu

296 display distinct transcriptional profiles in high-throughput transcription analyses.

297 ombine targeted mcircRasGEF1B depletion with high-throughput transcriptomic analysis to gain insight

298 igm for environmental health but still lacks high-throughput, user-friendly technology.

299 High-throughput UV-vis titrations in combination with ch

300 measure integrin-binding of RGD-peptides in high-throughput without using cells, ECM-proteins, or an