ライフサイエンスコーパス: high-turnover

1 h and will be greatest in populations with a high turnover.

2 roendocrine origin, but also in tissues with high turnover.

3 F-actin and regulatory proteins that undergo high turnover.

4 en anthracene and maleimide derivatives with high turnover.

5 aflatoxin B1, naphthalene, and styrene, with high turnover.

6 ecay showed the Aire(+) population to have a high turnover.

7 High turnovers (10(5)) and turnover frequencies (10(4) h

8 es P450 2D6, 3A4, and 4F2 are high-affinity, high-turnover anandamide oxygenases in vitro, forming th

9 were mainly characterized by low dispersal, high turnover and genetically differentiated populations

10 otein kinase can simultaneously achieve both high turnover and good substrate binding properties.

11 always, associated with tissues that display high turnover and high levels of protein synthesis.

12 These include constraints of time, high turnover and the need for early and effective disch

13 Epithelial and hematopoietic cells have a high turnover and their progenitor cells divide continuo

14 os identified a pool of dynamic F-actin with high turnover at EC junctions in vessels.

15 s, as observed previously, with particularly high turnover at super-enhancers.

16 known actions of TNFalpha, we attribute the high-turnover bone loss to an expanded osteoclast precur

17 Therapies tailored specifically to low- or high-turnover bone may treat renal osteodystrophy more e

18 ls expressed telomerase and, in spite of the high turnover, built up a telomeric reserve.

19 sign of a supramolecular catalyst capable of high-turnover catalysis is reported.

20 drogen bonding with C-H activation to obtain high-turnover catalytic regioselective functionalization

21 f the proliferation of lymphocytes and other high-turnover cell populations in vivo can be accomplish

22 We found that, without prior assumptions, high turnover could be used to identify regions involved

23 phoribosyl pyrophosphate amidotransferase, a high-turnover enzyme of the purine biosynthetic pathway

24 se superfamily has evolved in the "extremely high turnover" fashion: numerous losses and duplications

25 enase enzymes use Ni and Fe to oxidize H2 at high turnover frequencies (TOF) (up to 10,000 s(-1)) and

26 e showed that Au/Pd-TiO2 catalysts give very high turnover frequencies (up to 270,000 turnovers per h

27 l or aryl) at the 5 position are crucial for high turnover frequencies and good enantioselectivities.

28 The high turnover frequencies of CoFeOx and CoFeNiOx at low

29 s sets in at about 300 mV overpotential with high turnover frequencies that outperform other metal-or

30 Redox enzymes have high turnover frequencies, typically 10-1000 s(-1), and

31 Under a strong acidic environment, a high turnover frequency (TOF) of ~2.2 x 10(-3) s(-1) per

32 Our study reveals the origin of the high turnover frequency (TOF), and excellent durability

33 alyst oxidizes water with low overpotential, high turnover frequency and minimal degradation.

34 ater oxidation under these conditions with a high turnover frequency of 33 s(-1).

35 MMBL polymerization reaches an exceptionally high turnover frequency up to 122 s(-1) and a high initi

36 yst transfer and its effect on the continued high turnover frequency.

37 alyst is endowed with a good stability and a high turnover frequency.

38 It was assumed that they have a high turnover from blood-borne monocytes.

39 pared with normal or low turnover, bone with high turnover had material and nanomechanical abnormalit

40 romising tool in transfusion medicine and in high turnover/high activation platelet disorders.

41 1.09 [95% CI, 1.07-1.11]), 39% lower odds of high turnover hospitalization (odds ratio [OR], 0.61 [95

42 me measures included (1) length of stay, (2) high turnover hospitalization, (3) total hospital cost,

43 e upslope shift may have been accelerated by high turnover in canopy trees that provided opportunitie

44 lower bioavailability in rat and dog, and a high turnover in human hepatocytes.

45 Problems with high turnover in nursing and of maintaining adequate num

46 ter molecule, and short residence times with high turnover involving multiple water molecules.

47 oxidation actuate amide bond formation with high turnover is offered.

48 In addition, a high turnover number (>3000) can be achieved.

49 rdered loops that may explain the relatively high turnover number (280 s(-1) at pH 7.0) toward CDNB.

50 polymerization of acetylenes and exhibits a high turnover number (4371), activity (1.05 x 10(6) g(PP

51 (-1) g(-1) under full arc), which leads to a high turnover number (TON) of over 641 after 6 h.

52 rate reductase (Frd) is notable both for its high turnover number and for its production of substanti

53 a high level of expression and a relatively high turnover number of the efflux pumps in gram-negativ

54 ithout loss of activity and selectivity, and high turnover number was obtained.

55 tudies of P450BM-3 due to its high affinity, high turnover number, and increased solubility as compar

56 High turnover numbers (ca. 54,000) and turnover frequenc

57 the palladacycles have been used to generate high turnover numbers (TON's) and turnover frequencies (

58 is long-lived and remarkably efficient with high turnover numbers (TONs) and turnover frequencies (T

59 High turnover numbers (up to 2000 for homocoupling of 1-

60 ons to alkynes and cycloisomerizations, with high turnover numbers at room temperature or slightly el

61 ctional groups and displayed unprecedentedly high turnover numbers of approximately 2.5 x 10(6) and t

62 Impressively, sal-Fe-MOF displayed very high turnover numbers of up to 145000 and was recycled a

63 ly, the Mg-functionalized MOF displayed very high turnover numbers of up to 8.4 x 10(4) for ketone hy

64 High turnover numbers reflect the enhanced stability of

65 ge of ethers with excellent mass balance and high turnover numbers under 1 atm of O2 with no need for

66 oxygen production rates up to 286 s(-1) and high turnover numbers up to 55,400.

67 road detection window ranging from single to high turnover numbers.

68 lyze oxidation reactions, in some cases with high turnover numbers.

69 te carbon monoxide from CO2 selectively with high turnover numbers.

70 were defluorinated with high conversions and high turnover numbers.

71 y fast gliding motility, the parasite uses a high turnover of actin polymerization and adhesion sites

72 We found a high turnover of AMF with < 12% of VT present in all veg

73 e from degradation of nucleic acids due to a high turnover of cells in the bladder itself.

74 -mediated drug disposition consistent with a high turnover of endogenous uPA.

75 The testis exhibits relatively high turnover of endothelial cells.

76 iency accelerates telomere shortening during high turnover of hematopoietic cells and promotes telome

77 enetic determination of flowering time and a high turnover of individual plants argues strongly for t

78 equate implementation of the intervention, a high turnover of patients in the intervention units, com

79 re released into the intestinal lumen by the high turnover of the intestinal epithelium.

80 on a relatively long time scale despite the high turnover of the microtubules that comprise it.

81 Our data show a high turnover of transcriptional states between taxa and

82 This was accompanied by a high turnover of tumor cells.

83 to the next or within epidemics) there is a high turnover of variants within genotypes.

84 onstrate that most chromatin proteins have a high turnover on chromatin with a residence time on the

85 in patients with end-stage renal disease: a high-turnover osteodystrophy characterized by osteitis f

86 e-dependent loss of bone mass that resembles high-turnover osteoporosis in humans.

87 ay present a viable therapeutic strategy for high-turnover osteoporosis.

88 vere bone loss, as reported in patients with high-turnover, postmenopausal osteoporosis.

89 ells are a distinctive TRM population with a high turnover rate and a unique phenotype influenced by

90 membrane channels in embryonic cones have a high turnover rate because inhibition of protein synthes

91 This high turnover rate necessitates profound control mechani

92 f nuclear bomb test-derived (14)C revealed a high turnover rate of endothelial cells throughout life

93 This high turnover rate reveals a large and rapid mycorrhizal

94 ly bound pool, and a dynamic bound pool with high turnover rate that exchanges with the cytoplasmic p

95 a2+ exchanger (NCX1) is thought to achieve a high turnover rate, but all estimates to date are indire

96 (2+) and this protein possesses a relatively high turnover rate.

97 ation of closed hexameric toroids capable of high turnover rates and amenable to allosteric regulatio

98 stability of pre-mRNA species with different high turnover rates and investigated potential correlati

99 treating FGE with copper(II) is required for high turnover rates and yields.

100 bstrate and 2,4,6-trichlorophenol also gives high turnover rates in enzymatic studies.

101 90% or higher ee, good regioselectivity, and high turnover rates).

102 Both Npas4 mRNA and protein had high turnover rates, and, at the protein level, degradat

103 the start of treatment and, for cancers with high turnover rates, combination therapy is less likely

104 maintain both high substrate affinities and high turnover rates, the phosphorylation of the yeast RN

105 which are common in regulatory proteins with high turnover rates.

106 re in the mechanism of fumarate reduction at high turnover rates.

107 are dominated by weak ties characterized by high turnover rates.

108 n decoupling of the proton pump but maintain high turnover rates.

109 For very high-turnover rates, increasing the number of drugs used

110 in in the vicinity of the heme iron; (b) the high turnover regio- and stereoselective metabolism of a

111 Cytochrome P450 BM-3 catalyzes the high turnover regio- and stereoselective metabolism of a

112 Uremic mice exhibited high turnover renal osteodystrophy; treatment with sevel

113 nover was also significant (hazard ratio per high-turnover shift, 1.04; 95% CI, 1.02 to 1.06; P<0.001

114 he pulse-chase model artificially eliminated high-turnover solutions.

115 rt a population of renal myofibroblasts in a high turnover state and in matrix deposition.

116 cantly reduced, and most TEM maintained very high turnover throughout anti-IL-15 treatment.

117 In cycling tissues that exhibit high turnover, tissue maintenance and repair are coordin

118 ncapping, causing defects most pronounced in high-turnover tissues including intestinal epithelium.

119 rogressive atrophy and functional decline in high-turnover tissues.

120 ensure maintenance of tissue homeostasis in high-turnover tissues.

121 sin to switch during S phase from a state of high turnover to one capable of tenaciously holding sist

122 he poly(propylene oxide) in high yields with high turnover (TON>2000), which renders this the most ac

123 High turnover was seen at enhancers, as observed previou

124 , where normal mouse bone marrow cells (i.e. high turnover) were evaluated post labeling, demonstrate

125 , low in D-aspartate, may represent areas of high turnover where D-aspartate may be physiologically i