ライフサイエンスコーパス: higher order

1 sel-SHARPER is also applicable to first- and higher-order (1)H spectra.

2 evealed large interaction domains (TADs) and higher order A and B compartments, reflecting active and

3 rration (P = .018), coma (P = .23) and total higher order aberrations (P = .31).

4 ganization after stroke interact to generate higher order and distinct concepts of regenerative brain

5 lt mammals in the bone marrow, a tissue with higher-order architectural and functional organization t

6 powerful tool through which we can study the higher-order architectural properties of the world aroun

7 orms of learning that have been regarded as "higher order" are computationally more complex than "sim

8 neously in the primary auditory cortex and a higher-order area, the posterior auditory field, known t

9 how information about sounds is conveyed to higher-order areas for further processing and localizati

10 s developmental experience and suggests that higher-order areas involved in the cross-modal reorganiz

11 ed the primary auditory cortex; knowledge of higher-order areas is limited to effects of cross-modal

12 tions in auditory cortex by projections from higher-order areas, including the hippocampus and fronta

13 These cortical areas are involved in higher-order aspects of cognition and affect.

14 Herein, we study how the ability to form higher-order assemblies influences the recruitment of th

15 e characteristic clustering of caveolae into higher-order assemblies is absent; and (2) when the EHD1

16 -a-string-like structure of nucleosomes into higher-order assemblies is crucially linked to nuclear p

17 form oligomers that recapitulate some of the higher-order assemblies observed crystallographically.

18 Higher-order assemblies of proteins, with a structural a

19 CTD contains repeated tyrosines that mediate higher-order assembly of Rbfox/LASR and are required for

20 ernative splicing choices also depend on the higher-order assembly of these regulators within the nuc

21 ent developmental associations, with PSCs in higher-order association cortex networks showing greater

22 and somatomotor networks and diminishing in higher-order association cortex.

23 Motivated by the potential higher order associations, several studies investigated

24 Further, cocaine rats were unable to learn higher-order associations and even altered simple condit

25 We demonstrate GINOM's ability to identify higher-order associations with both simulated and real d

26 e subdivisions of PPC in the rat as diverse, higher order associative cortical areas, comparable to t

27 re studied in roots and shoots of single and higher-order atlazy mutants.

28 herefore, cross-modal plasticity in the deaf higher-order auditory cortex had limited effects on audi

29 resent study examined neural activity in the higher-order auditory cortex Te2 and basolateral amygdal

30 We also show that higher-order auditory cortical areas, by contrast, repre

31 We also show that higher-order auditory cortical areas, by contrast, repre

32 Here, we studied a higher-order auditory field responsible for the supranor

33 er thickness is observed in both primary and higher-order auditory fields in layer IV and infragranul

34 microscale engineering approach to inducing higher-order behaviour in mixed populations of synthetic

35 omplex process involving the spinal cord and higher order brain structures.

36 is of the relationship between breathing and higher-order brain activity is unknown.

37 Putative sleep-wake centers are located in higher-order brain centers that are indirectly connected

38 Slit and Robo receptors in wiring Drosophila higher-order brain circuits and identified differences i

39 ter neural circuits, autonomic function, and higher-order brain function and behavior.

40 disruption in temporal communication between higher-order brain regions associated with mental time t

41 they are not redundant for formation of the higher order chemoreceptor arrays that are known to form

42 -dimensional genome organization destabilize higher order chromatin at specific loci that regulate re

43 and may be dispensable for the formation of higher order chromatin organization.

44 rget genes Foxa2 and Lhx1 is associated with higher order chromatin reorganisation.

45 it DNA of nucleosomes and linker DNA to form higher order chromatin structures with distinct transcri

46 ation, followed by progressive maturation of higher-order chromatin architecture during early develop

47 l protein with a critical role in connecting higher-order chromatin folding in pluripotent stem cells

48 introduce methylation channels and show that higher-order chromatin organization can be predicted fro

49 Higher-order chromatin organization controls transcripti

50 Our results indicate that higher-order chromatin regulation may be an integral par

51 des an update on the mechanisms that control higher-order chromatin remodeling in the context of epid

52 Analysis of higher-order chromatin structure data and RNA polymerase

53 Fertilization triggers assembly of higher-order chromatin structure from a condensed matern

54 powerful tool for investigating the role of higher-order chromatin structure in gene regulation.

55 with nucleosomes to promote the formation of higher-order chromatin structure, but the underlying mol

56 er and enhancer interactions and topology of higher-order chromatin structure.

57 For proper information output, higher-order chromatin structures can be regulated dynam

58 ey are prerequisites for further assembly of higher-order chromatin structures that are refractory to

59 f cohesin-dependent loop extrusion generates higher-order chromatin structures within the one-cell em

60 al domain, which is critical for stabilizing higher-order chromatin structures.

61 d condensin, which are the key components of higher-order chromatin structures.

62 trated H4K20me1's pivotal role in regulating higher-order chromosome structure and X-chromosome-wide

63 rect link between chromatin modification and higher-order chromosome structure in long-range regulati

64 Chromatin modification and higher-order chromosome structure play key roles in gene

65 d Smc5/6 are involved in the organization of higher-order chromosome structure-which is essential for

66 By contrast, higher-order circuit adaptations are not apparent, sugge

67 survival, but a complete wiring diagram of a higher-order circuit supporting associative memory has n

68 oo little is known about their assembly into higher-order clusters.

69 ons, and the other involves areas related to higher order cognition.

70 ome of the deleterious effects of anxiety on higher-order cognition.

71 medial prefrontal cortex plays a key role in higher order cognitive functions like decision making an

72 The prefrontal cortex is responsible for higher order cognitive processing, and prefrontal dysfun

73 s identify a novel neural pathway regulating higher-order cognitive aspects of feeding behavior.

74 gence as well as better function in multiple higher-order cognitive domains.

75 understanding on how MD-PFC circuits support higher-order cognitive function.

76 ize rapid and vigilant reactions over slower higher-order cognitive functions is essential for adapti

77 frontoparietal cortex is believed to reflect higher-order cognitive functions rather than external se

78 in the brain associated with a wide range of higher-order cognitive functions.

79 can occur without conscious intent or other higher-order cognitive process.

80 n efficient interface between perception and higher-order cognitive processes.

81 This indicates that morphologies of natural higher-order collagen packing might be rooted in the cha

82 with sensitivity enhancement via the use of higher order comb modes from an electro-optic comb for u

83 operties as the intact objects, but lack the higher-order combinations of features that are character

84 lecular interface; this heterodimer formed a higher order complex with a second K1-K10-2B heterodimer

85 mutations around the interface destabilized higher-order complex formation and altered the cooperati

86 d key residues in the interface required for higher-order complex formation and long-term plasmid mai

87 ed both its activity and its ability to form higher-order complexes in transfected cells and in vitro

88 se proteins to accumulate at mitochondria in higher-order complexes than those formed in the absence

89 toire by forming different context-dependent higher-order complexes.

90 hores, which should inform future studies of higher-order complexes.

91 ral and acidic conditions reveal areas where higher order conformational changes occur on the amino-a

92 Eukaryotic chromosomes are folded into higher-order conformations to coordinate genome function

93 rackers, GTs) are better able to incorporate higher-order contextual information, perhaps because of

94 ut with strong constraints on the resultant "higher-order cooperativities." Even with such integratio

95 rent network structure produces pairwise and higher-order correlated activity, and how nonlinearities

96 nse of monolayer MoSe2 and identify multiple higher-order correlated states.

97 Similar strategies for parcellating higher-order cortex have proven elusive.

98 tients with cognitive motor dissociation and higher-order cortex motor dissociation recovered beyond

99 Higher-order cortex motor dissociation was identified in

100 nses during language and music stimuli (i.e. higher-order cortex motor dissociation); and (ii) early

101 the retina, while remaining more elusive in higher order cortical regions.

102 phalography can detect command-following and higher-order cortical function in patients with acute se

103 However, in most higher-order cortical sites, it is unknown whether such

104 e are currently no robust methods to profile higher order cysteine oxidation.

105 lation may not be complete, especially among higher order cytotypes.

106 Higher-order data generation implies some automation cha

107 uipment hyphenation are the key to obtaining higher-order data, the required simultaneous control of

108 heoretical studies have been devoted to such higher-order degeneracies, their experimental demonstrat

109 ost them, except for nonlinear theories with higher-order derivatives such as the Skyrme-Faddeev mode

110 Fabrics displaying higher-order diffraction peaks in the visible regime wer

111 able functions including the construction of higher-order DNA assemblies at the cell surface and prog

112 G-quadruplexes (G4s) are higher-order DNA structures typically present at promote

113 egion) identities that produce the acini and higher order ducts, respectively.

114 ue T585 as a joint that links and stabilizes higher-order EBNA1 complexes.

115 can have cascading impacts on understanding higher order ecological phenomena, such as pathogen pers

116 The impacts of length dependent higher-order effects, linear and nonlinear losses includ

117 system act in synergy, sometimes leading to higher-order, emergent phenomena.

118 e characterization of rank orders that imply higher order epistasis.

119 ding of key molecular pathways that underlie higher order events such as cell cycle control, developm

120 Of particular interest is the use of even higher-order exceptional points (greater than second ord

121 Here we report the observation of higher-order exceptional points in a coupled cavity arra

122 ernal magnetic fields, stray field energies, higher-order exchange interactions and the Dzyaloshinski

123 Unidimensionality was confirmed by higher order factor analysis.

124 tereotypy, while not significantly affecting higher order features of song such syllable-type usage (

125 uch as chromosomally interacting domains and higher order features such as centromere clustering.

126 the affinity of the specific motif site and higher-order features of the larger genomic locus, such

127 in our model receive sensory information and higher-order feedback in electrotonically segregated com

128 ty consistent with the D-periodic banding of higher-order fibers assemblies.

129 The Gabor zone plate, which suppresses the higher-order foci to a pair of conjugate foci, is an att

130 These findings indicate that the higher order folding of chromatin topology may act as a

131 condensation, sister chromatid cohesion, and higher order folding of interphase chromatin are mediate

132 -tracts in DNA linkers may control chromatin higher-order folding and thus influence cellular process

133 cture of the core tetrameric HIV-1 STC and a higher-order form that adopts carboxyl-terminal domain r

134 ify interactions between SCPs as a basis for higher order function in a context dependent manner, all

135 A higher-order function may evolve phylogenetically if it

136 he arrangement of cells within organs endows higher-order functionality through a structure-function

137 ulticellular structural organization reveals higher order functions for patterning and principles of

138 long-chain macromolecules needed to support higher-order functions in living systems (e.g., polypept

139 in human may contribute to species-specific, higher-order functions.

140 MYC's promoter is governed by a higher order G-quadruplex (G4) structure in the NHE III1

141 ess occurring in a variety of materials; the higher orders generation is generally less efficient tha

142 ent transcriptional deregulation mediated by higher order genome architecture.

143 in tolerating drugs or induce disease; (iv) higher order genome organization; and (v) host-factors t

144 ts that Mediator plays a significant role in higher-order genome organization.

145 Our results define a higher-order genomic instability element that has shaped

146 igh resolution of the faradaic signal in the higher order harmonics and the fact that a single electr

147 ty profile of the launched beam and also the higher-order harmonics that were not reported previously

148 Membrane proteins frequently assemble into higher order homo- or hetero-oligomers within their natu

149 Our results suggest that higher order homotypic and/or heterotypic interactions w

150 ssor NaCl, and by indirectly controlling the higher-order idler phase through tuning the signal (2.4-

151 he precatalyst, A = (COD)Ir.POM(8-), not the higher order implied by classic nucleation theory and it

152 ns in primary sensory processing centers and higher order integration centers, whereas AT immunoreact

153 nse signals derive from the mushroom bodies, higher-order integration centers for olfactory, visual,

154 by jointly testing for genotypic effect and higher order interaction effects between genotype, methy

155 For all systems, our approach revealed higher order interactions among mutations.

156 In our framework, higher-order interactions are completely defined by pair

157 ons, and chromosome compartments, defined as higher-order interactions between TADs sharing functiona

158 Although higher-order interactions have been studied for decades,

159 We show that higher-order interactions have strong effects in models

160 The inclusion of higher-order interactions in competitive network models

161 ld persist thanks to the stabilizing role of higher-order interactions, in which the presence of a sp

162 ifically the presence of relatively stronger higher-order "jumping links" between nonadjacent perisyl

163 eby providing insight into the mechanisms of higher order learning.

164 iscriminative models from (i) first-order to higher-order linear-chain CRFs, and from (ii) first-orde

165 Preferential adsorption of higher order liquid polysulfides and subsequent conversi

166 hains that coalesce to form microfibrils and higher-ordered macrofibrils.

167 solvent-dependent dynamic properties of the higher-order mechanically interlocked molecule.

168 tworks (RSNs) involved in internally-guided, higher-order mental functions (default mode, central exe

169 les with divergent protofilament numbers and higher-order microtubule assemblies have been discovered

170 d state is unknown, previous observations of higher-order MinE self-association may explain this inhi

171 uate size variations, it invariably leads to higher-order moments growing unboundedly over time.

172 ivities, but that their amplitude depends on higher-order moments of the heterogeneity.

173 ain how HIV-1 IN, which self-associates into higher-order multimers, can form a functional intasome,

174 is monomeric and sequestered when SMN forms higher-order multimers.

175 and homicide, may be higher among twins and higher-order multiples than among singletons in the Unit

176 Twins and higher-order multiples were at greater risk of infant mo

177 odulators through the analysis of single and higher order mutants of IRE1, bZIP60, bZIP28 and BI1 in

178 lution microscopy to reveal the existence of higher-order NEMO lattice structures dependent on the pr

179 es in the CNS has important consequences for higher-order nervous system function (e.g., [1-4]), and

180 Such higher order network interactions contribute in unexpect

181 r knowledge, this is the first work to apply higher-order network analysis to study PM 2.5 transport.

182 r, due to the weak intrinsic response of the higher-order nonlinear processes.

183 G-quadruplex (G4) is a higher-order nucleic acid structure that is formed by gu

184 ped to track and label G-quadruplexes: these higher-order nucleic acid structures originate in the as

185 ealed that ParB dimers tetramerize to form a higher order nucleoprotein complex.

186 The intasome, a higher-order nucleoprotein complex composed of viral int

187 The role of the early visual cortex and higher-order occipitotemporal cortex has been studied ex

188 sis revealed that MCU oxidation promotes MCU higher order oligomer formation.

189 of the peptide and formation of dimeric and higher order oligomeric receptor multimers.

190 propose that EBNA1 dimers can assemble into higher-order oligomeric structures important for diverse

191 role of the C-terminal tail region of IN in higher order oligomerization of intasomes, potentially i

192 ranging from monomers, dimers, tetramers to higher order oligomers to generate a double strand break

193 loroplast, where it associated in dimers and higher order oligomers.

194 ing evidence suggests that Abeta trimers and higher-order oligomers derived from trimers have special

195 n the oligomerization state of Spc110p, with higher-order oligomers dramatically enhancing the stabil

196 cidating the structures of these trimers and higher-order oligomers is paramount for understanding th

197 y deciphering the distribution of dimers and higher-order oligomers of K-Ras4B, the most frequently m

198 R stress conditions causes IRE1alpha to form higher-order oligomers that exhibit continuous activatio

199 emonstrate that the Ml proteins studied form higher-order oligomers through their N-terminal region a

200 Many membrane proteins are known to form higher-order oligomers, but the degree to which membrane

201 Ang1 binding may cross-link Tie2 dimers into higher-order oligomers, potentially explaining how Tie2

202 dimer with EGFR in the absence of detectable higher-order oligomers.

203 As low-level, sensory processing impacts higher-order operations, such sensory anomalies can cont

204 Higher-order organisms produce surface-active proteins w

205 The framework reveals higher-order organization in a number of networks, inclu

206 We apply higher-order organization of complex networks to identif

207 Our results demonstrate that the higher-order organization of HER receptors is an essenti

208 del of cortical tactile processing, in which higher-order perceptual processing depends upon informat

209 the hypothesis that immunity to malaria is a higher-order phenomenon related to a pattern of response

210 amined how circadian rhythms are affected in higher order pif mutants and the mechanisms by which PIF

211 at the cardinal points of the corresponding higher-order Poincare sphere.

212 Postzygotic isolation was weaker among higher order polyploids than between diploids and tetrap

213 going interploid gene flow, especially among higher order polyploids, which may slow divergence and s

214 subclass of astrocytes found exclusively in higher-order primates.

215 ons, and of representations underlying other higher-order processes, is unknown.

216 modulatory role in sensory input regions and higher order processing centers in the desert ant brain.

217 relative investment in both lower-order and higher-order processing regions in the brain responsible

218 per-enhancers have been proposed to manifest higher-order properties important in development and dis

219 ons at different time points, as well as the higher-order properties of multisensory integration, suc

220 Both robustness and plasticity in this higher order property of atrichoblast patterning was obs

221 gy in health and disease and an unrecognized higher-order property of super-enhancers in RNA processi

222 e/tyrosine repeats that mediate formation of higher-order protein assemblies implicated in gene regul

223 and gel-filtration chromatography to define higher-order protein complexes containing K-H scaffoldin

224 They are thought to form higher-order protein complexes for their functions, but

225 d periodically modulated propagation for the higher-order pure-quartic solitons.

226 However, these higher-order radiative processes are usually quenched in

227 ary Supplements for several years to develop higher-order reference measurement procedures and Standa

228 emarkable hierarchical order from primary to higher-order regions, unparalleled structural and functi

229 ns as a novel substrate of importance in the higher-order regulation of feeding behavior.

230 However, the whole picture of such higher-order regulatory modules across the transcriptome

231 omers are organized into chromosome-specific higher-order repeats (HORs) that are reiterated thousand

232 ified 394 repeated coding motif variants and higher-order repetitive cassette structures unique to sp

233 entations of the specific physical cues or a higher-order representation of auditory space (i.e., int

234 Together, these results suggest a higher-order representation of auditory space in the hum

235 are their inputs to predictions derived from higher-order representations and signal their deviation

236 multilayer architectures to identify useful higher-order representations-the hallmark of deep learni

237 Although viral IRES typically contain higher-order RNA structure, an unstructured sequence of

238 oth sustained and diverse mental operations, higher-order RSNs had lower metastability and synchrony.

239 enerate and dynamically control well-defined higher-order (secondary) conformations of the SP backbon

240 ear-chain CRFs, and from (ii) first-order to higher-order semi-Markov CRFs (semi-CRFs).

241 likely allowed for more complex synchrony of higher-order sensorimotor coordination, proprioceptive a

242 Moreover, the first-order and higher-order sensory and motor nuclei across different m

243 tion, we tested a new strategy for attaining higher-order signal amplification, in which a target seq

244 ms, ranging from bacteria, through fungi, to higher order species, including humans, comprising two-s

245 Higher-order states, such as bound biexcitons, are possi

246 ombine lower-level sensory signals to detect higher-order stimulus features critical to survival, suc

247 oop structure, or to interconversion between higher-order structural conformations of a G-rich motif,

248 yl NMR provides a powerful tool to probe the higher order structure (HOS) of monoclonal antibodies (m

249 Understanding protein higher order structure and interfacial interactions is c

250 first tetrapods to man, that is crucial for higher order structure self-assembly of the key intrinsi

251 To identify and quantify such higher order structure, we applied Raman optical activit

252 sociation (UVPD) for the characterization of higher order structure.

253 Higher-order structure (HOS) is a crucial determinant fo

254 rikingly, chromatin shows greatly diminished higher-order structure after fertilization.

255 oligomeric state of FtsA may influence FtsZ higher-order structure and divisome function.

256 a high-throughput manner for batch-to-batch higher-order structure comparison, as well as for the op

257 tures remain rare, despite the importance of higher-order structure in biomacromolecules.

258 The usefulness of the higher-order structure information provided by hydrogen/

259 We detected the presence of a localized higher-order structure motif in the pro-part of proNGF.

260 ified by the folded secondary, tertiary, and higher-order structure of biomolecules.

261 nucleosomes, which further compact into the higher-order structure of chromatin.

262 fferences in morphology and composition, the higher-order structure of the inner and outer rings is u

263 ippocampal patients were unable to grasp the higher-order structure of the task with the same success

264 We find evidence for higher-order structure within satDNA arrays that suggest

265 his hypothesis depends on the formation of a higher-order structure, which has yet to be identified u

266 iversify their molecular fate while adopting higher-order structure.

267 a well-known technique for studying protein higher-order structure.

268 by linking PRC1 to formation of a repressive higher-order structure.

269 Moreover, a higher-ordered structure, Co-Ni-Cu-O, was found to follo

270 he scaffold for describing the mechanisms of higher order structures as organelles and cells.

271 ture epitopes displayed on E-homo-dimers and higher order structures.

272 anization of individual building blocks into higher order structures.

273 asing attention due to their ability to form higher ordered structures similar to proteins.

274 Significantly, higher-order structures (oligonucleotides, peptides and

275 ed a nuclear imaging system to visualize the higher-order structures along with their dynamics in liv

276 (4.8.8) and (3.6.3.6), and one pattern with higher-order structures beyond the complexity observed i

277 interactors of insoluble proteins that form higher-order structures have remained challenges in biol

278 e mechanisms that fold chromatin fibers into higher-order structures is therefore key to understandin

279 Higher-order structures like fibril bundles and fibers a

280 ence-directed versatile assembly of periodic higher-order structures reveals a general organizational

281 bles the self-assembly of the particles into higher-order structures.

282 o influence the assembly and architecture of higher-order structures.

283 dynamics and the formation of VPS-dependent higher-order structures.

284 generation of the corresponding oligomers or higher-order structures.

285 interactions within the nucleosome unit and higher-order supercoiled chromatin leading to neutraliza

286 h as words and nucleotides that give rise to higher order syntactic constructs.

287 tum dynamics to guide the rational design of higher-order synthetic circuits consisting of multiple d

288 nker histone (H1)-dependent stabilization of higher order 'tertiary' chromatin structures but do not

289 ion of tumor-to-background-based general and higher-order textural features by applying 5 different b

290 of arrhythmic activity was localized to the higher-order thalamic relays of the medial dorsal nucleu

291 his arrhythmic activity was localized to the higher-order thalamic relays of the medial dorsal nucleu

292 d a modified version of what is known as the higher-order theory of consciousness.

293 atives must move beyond city-level data to a higher-order understanding of cities as transboundary, m

294 segmentation hypothesis holds within leaves, higher order veins that are most terminal in the plant h

295 Increased vulnerability in the higher order veins would also be consistent with these e

296 and subcortical structures participating in higher order visual processing.

297 and propagate to retinal ganglion cells and higher-order visual areas, but the mechanism responsible

298 entral and peripheral representation of five higher-order visual areas, V2/18, V3/19, V4/21a,V5/PMLS,

299 rapidly combined into global information in higher-order visual areas, where conscious percepts emer

300 and superior frontal gyrus) and primary and higher-order visual, somatosensory and motor areas (d: -