ライフサイエンスコーパス: higher organism

1 tat1 (alpha-tubulin acetyltransferase 1) per higher organism.

2 of how miRNAs function in the development of higher organisms.

3 ction of hydrogen sulfide, which is toxic to higher organisms.

4 ction on DNA in bacteria and in chromatin of higher organisms.

5 peat structures found in the genomes of most higher organisms.

6 onal interaction has yet to be identified in higher organisms.

7 uggest a similar pathway may be conserved in higher organisms.

8 mic sequence, and they define cell status in higher organisms.

9 ted extensively to manipulate the genomes of higher organisms.

10 ughter cells in a process akin to mitosis in higher organisms.

11 control of developmental gene expression in higher organisms.

12 deal with the complex functional demands of higher organisms.

13 or the regulation of phenotypic diversity of higher organisms.

14 cient secretion of all collagen molecules in higher organisms.

15 ids are regulators of body shape and size in higher organisms.

16 nism controlling protein localization in all higher organisms.

17 circuits controlling spatial orientation in higher organisms.

18 minant of tissue size in both Drosophila and higher organisms.

19 imal phyla suggests mechanistic relevance to higher organisms.

20 rm our understanding of germ cell biology in higher organisms.

21 ggests spatial organization of glycolysis in higher organisms.

22 ays previously known to be available only to higher organisms.

23 but significantly less than that observed in higher organisms.

24 functional genomics and network inference in higher organisms.

25 s critical for the proper development of all higher organisms.

26 ein diversity in eukaryotes, particularly in higher organisms.

27 is essential for normal development in many higher organisms.

28 a signaling molecule and cytotoxic agent in higher organisms.

29 icardial-myocardial interactions relevant to higher organisms.

30 m to enhance cellular transport in yeast and higher organisms.

31 enorhabditis elegans, but is not possible in higher organisms.

32 ion dominate the mRNA stability landscape in higher organisms.

33 t, metabolism, and aging in nematodes and in higher organisms.

34 ntrol of gene expression may have evolved in higher organisms.

35 important families of structural proteins in higher organisms.

36 lex gene expression patterns particularly in higher organisms.

37 mpaction within defined chromatin domains in higher organisms.

38 ionally effective mimics of glycoproteins in higher organisms.

39 ure-function relations with P2X receptors of higher organisms.

40 onfer extracellular and nuclear functions in higher organisms.

41 on may serve as a regulatory modification in higher organisms.

42 yotes to their ability to elicit immunity in higher organisms.

43 ogenetic patterns that may have parallels in higher organisms.

44 lutionary conservation of the Gcm cascade in higher organisms.

45 hat distinguish it from the complex of other higher organisms.

46 and the impact mitochondria have on aging in higher organisms.

47 nt can be found in developmental programs in higher organisms.

48 ommunication and other processes specific to higher organisms.

49 erve transmission and the immune response of higher organisms.

50 uggests that they may serve some function in higher organisms.

51 to regulate complex segmental body plans in higher organisms.

52 e RNase P holoenzyme from archaebacteria and higher organisms.

53 uggest a unique regulatory role for eIF3k in higher organisms.

54 of functions appears to be conserved in all higher organisms.

55 nding tissue-level electric field effects in higher organisms.

56 c changes in viruses, bacteria, and genes of higher organisms.

57 eton play an important role in cell shape in higher organisms.

58 ight regulate critical cellular processes in higher organisms.

59 haracteristic of all grasses and perhaps all higher organisms.

60 m for understanding dopaminergic function in higher organisms.

61 l wave formation in the respiratory cilia of higher organisms.

62 ing domains has so far been observed only in higher organisms.

63 er, little is known about PMR1 homologues in higher organisms.

64 molecules that carry out analogous roles in higher organisms.

65 an reveal novel components and mechanisms in higher organisms.

66 stows upon bacteria some of the qualities of higher organisms.

67 tion of other symbiotic associations between higher organisms.

68 ome bacterial cytochromes c(1) but absent in higher organisms.

69 ed to other aspects of aging in yeast and in higher organisms.

70 mic and proteomic data, both in yeast and in higher organisms.

71 y tissue-specific physiological responses in higher organisms.

72 e more complex signaling pathways present in higher organisms.

73 This pathway appears to be unique to higher organisms.

74 re critical for successful interactions with higher organisms.

75 for the annotation of complete genomes from higher organisms.

76 ns is of great importance to the survival of higher organisms.

77 rb regulatory systems that control ageing in higher organisms.

78 olutionary forerunner of P2Y(1) receptors of higher organisms.

79 ue domains are widespread among bacteria and higher organisms.

80 their role as agents of natural selection in higher organisms.

81 abolic rate and aging in yeast and, perhaps, higher organisms.

82 gnition motifs within replication origins of higher organisms.

83 ed into much larger tRNA-binding proteins of higher organisms.

84 ant part of the energy homeostasis system of higher organisms.

85 -epimerase has been isolated previously from higher organisms.

86 gest that similar results may be obtained in higher organisms.

87 iption factors involved in such responses in higher organisms.

88 ction(s) related to embryonic development in higher organisms.

89 t for the wingless/wnt signaling pathways in higher organisms.

90 hromatin structure studies in both yeast and higher organisms.

91 undancy seems to be widespread in genomes of higher organisms.

92 hat could be used toward similar purposes in higher organisms.

93 action system itself-toward the evolution of higher organisms.

94 ancient and ubiquitous defense mechanism in higher organisms.

95 he extracellular matrix adhesion proteins of higher organisms.

96 ic adenosine deaminase that is widespread in higher organisms.

97 important role for 3'-UTRs in the biology of higher organisms.

98 complexes are highly conserved from yeast to higher organisms.

99 th several mechanistic aspects distinct from higher organisms.

100 and transfer through the aquatic food-web to higher organisms.

101 g cellular toxicities and ribosomopathies in higher organisms.

102 provides an essential source of N atoms for higher organisms.

103 ptimizing and widening their applications in higher organisms.

104 NAs in other bacteria and regulatory RNAs in higher organisms.

105 ulation, the sulphur cycle and signalling to higher organisms.

106 ental process underlying the behavior of all higher organisms.

107 ereby providing essential nitrogen atoms for higher organisms.

108 te highly important communication systems in higher organisms.

109 oli may help to predict toxicity patterns in higher organisms.

110 cular ageing factors conserved from yeast to higher organisms.

111 networks of chromatin-based interactions in higher organisms.

112 heir targets across bacterial species and in higher organisms.

113 anism regulating histone deubiquitination in higher organisms.

114 e a framework to study commensal biofilms in higher organisms.

115 ortant epigenetic modification in the DNA of higher organisms.

116 ce, a role for P4Hs that may be conserved in higher organisms.

117 involved in sensing touch and sound waves in higher organisms.

118 t account for the helicase domain present in higher organisms.

119 d regulation of distinct subsets of genes in higher organisms.

120 n is structurally homologous to hnRNP-C from higher organisms.

121 riety of oxidation reactions in microbes and higher organisms.

122 thylation is an epigenetic control factor in higher organisms.

123 questions about how these results relate to higher organisms.

124 ts is essential for survival and behavior of higher organisms.

125 ty to suggested mineralization mechanisms in higher organisms.

126 chromosome conformations in prokaryotes and higher organisms.

127 contributed to functional diversification in higher organisms.

128 c microorganisms pose severe problems to all higher organisms.

129 nctional precursor to the internal memory of higher organisms.

130 h, a simple form of learning usually seen in higher organisms [4].

131 ent from the specificity factors employed in higher organisms, a comparison of the sigma/RNA polymera

132 In higher organisms, a major pathway for repairing double s

133 ins to species richness are partly caused by higher organism abundance and are common in plants and b

134 ranzymes) play a critical role in protecting higher organisms against intracellular infections and ce

135 In higher organisms, alpha subunits of G proteins have been

136 Extensive in the brains of higher organisms, alternative splicing might be the prim

137 In higher organisms, aminoacyl-tRNA synthetases developed r

138 igh-pressure-inducible phenomena observed in higher organisms, anaesthetics antagonize high-pressure

139 n important tool for genetic manipulation of higher organisms and a model for site-specific DNA-recom

140 nated Sin3A and Sin3B have been described in higher organisms and although functional differences bet

141 stability and expression within the cells of higher organisms and can exhibit specific antigen recogn

142 is widely expressed in nearly all tissues of higher organisms and couples cellular energy status to m

143 ccurs in the mitochondria and peroxisomes in higher organisms and in the peroxisomes in yeast.

144 ing enzyme that is ubiquitously expressed in higher organisms and many prokaryotes.

145 system with features common to those used by higher organisms and outlines a novel mechanism for deli

146 provide an example of trans-kingdom RNAi in higher organisms and suggest the potential of bacteria-m

147 ggered regulatory hierarchies exist in other higher organisms and that Drosophila is providing our fi

148 of a battle for nutritional resource between higher organisms and their microbial pathogens.

149 se LIN proteins have also been identified in higher organisms, and here we analyze the MALS/Veli (mam

150 core set of regulatory factors conserved in higher organisms, and the complex pattern of EB1 targeti

151 tant consideration given that the genomes of higher organisms are riddled with partial tRNA sequences

152 ilin/Aip1 complex regulates, particularly in higher organisms, are yet to be determined.

153 ondrial receptors for DRP-1-like proteins in higher organisms as well and that BH3-only proteins play

154 Higher organisms as well as medical and technological ma

155 mbination and repair in bacteria, and in all higher organisms as well, due to the functional and stru

156 f the replication primosome subassemblies of higher organisms as well.

157 Homologous enzymes may be widespread in higher organisms, as sulfide-oxidizing activities have b

158 In many higher organisms, autocatalysis and decarboxylation are

159 This higher organism burden most likely impacted disease path

160 -deficient mice to succumb more quickly with higher organism burden, increased lung pathology, and de

161 meostatic control in physiologic response of higher organisms but is not well understood.

162 are often targets of natural selection among higher organisms, but quantifying the effects of such se

163 utes to the complexity of gene expression in higher organisms, but the regulation of the splice site

164 metal ions that are bound and transported in higher organisms by transferrin.

165 Cells of higher organisms can commit suicide in response to genom

166 Higher organisms can establish complex associations betw

167 Such behaviour in higher organisms can often be reduced to a few stereotyp

168 in genetics textbooks, gene transcription in higher organisms cannot be fully understood by analysing

169 In higher organisms, carnitine has specific functions in in

170 Casein kinase CK2 is an essential enzyme in higher organisms, catalyzing the transfer of the gamma p

171 The genome in a higher organism consists of a number of types of nucleot

172 hough they share similar folds, the FEN1s of higher organisms contain a 3'-extrahelical nucleotide (3

173 nase activity than is present in the PKGs of higher organisms containing only two allosteric sites.

174 t an intermediate degree of sensitivity, and higher organisms (containing cholesterol) are largely re

175 ese results we propose that GST evolution in higher organisms could be linked to the defense against

176 many neurotransmitter:sodium symporters from higher organisms depend on Cl(-) ions.

177 The growth and behavior of higher organisms depend on the accurate perception and i

178 Genetic efficiency in higher organisms depends on mechanisms to create multipl

179 The transcriptional machinery of higher organisms, despite its greater inherent complexit

180 Thus, higher organisms developed a strategy to make tRNA a reg

181 ultiple molecules and elements reflects that higher organism develops a complex translation regulator

182 This suggests that evolution of higher organisms does not suffer a 'cost of complexity'

183 t value to the study of related processes in higher organisms due to the growing evidence for the cro

184 Cell motility in higher organisms (eukaryotes) is crucial to biological f

185 ion during mitosis is thought to act, in all higher organisms, exclusively through the kinetochore.

186 triction and oxidative stress, features that higher organisms exploit in defending themselves against

187 Male meiosis in higher organisms features synchronous cell divisions in

188 h may prove useful to study gene function in higher organisms for which transgenic technology is avai

189 ic interactions might not become apparent in higher organisms for years.

190 ation events occurring within the genomes of higher organisms, for example, detecting alternative RNA

191 der to construct gene regulatory networks of higher organisms from gene expression and promoter seque

192 However, in higher organisms, fully effective TLS also requires a no

193 eded to generate molecular physical maps for higher-organism genomes.

194 unction and regulation of nicotinamidases in higher organisms has not been determined.

195 of the consequences of ageing on the HSR in higher organisms has not been documented.

196 wever, the complexity of circadian clocks in higher organisms has prevented a clear understanding of

197 Studying the consequences of DSBs in higher organisms has, however, been hindered by a scarci

198 t opening of the heme crevice, suggests that higher organisms have evolved to inhibit peroxidase acti

199 ed to test for dsRNA interference effects in higher organisms in which it is feasible to construct tr

200 r repeat (TTAGGG)n found at the telomeres of higher organisms including humans.

201 Ser/Thr kinase, plays critical roles in all higher organisms including plants.

202 likely to elucidate circadian timekeeping in higher organisms, including how transcription and transl

203 inform stem cell function and dysfunction in higher organisms, including humans.

204 ions of cell-cycle studies in C. elegans for higher organisms, including humans.

205 rapidly cataloguing and cloning the genes of higher organisms, including humans.

206 for our understanding of circadian clocks in higher organisms, including mammals.

207 netic program is evolutionarily conserved in higher organisms, including mammals.

208 Despite intense study in higher organisms, investigations of voltage and calcium

209 te that degradation of proteins by MPCs from higher organisms involves a nonprocessive mechanism comp

210 PEPCK from higher organisms is a monomer, specifically requires GTP

211 well defined in yeast, but its complexity in higher organisms is barely understood.

212 Cellular differentiation in higher organisms is generally considered irreversible, a

213 However, the translation control system of higher organisms is less understood.

214 Migration of cells in higher organisms is mediated by adhesion receptors, such

215 Perception of heat or cold in higher organisms is mediated by specialized ion channels

216 his overview is that the unit of function in higher organisms is neither the genome nor the cell alon

217 The complexity of higher organisms is not simply a reflection of the numbe

218 than half of the genome) of noncoding DNA in higher organisms is not well understood.

219 g evidence indicates that gene expression in higher organisms is regulated by RNA polymerase II stall

220 One of the unique characteristics of higher organisms is their ability to learn and adapt to

221 Gene expression in higher organisms is thought to be regulated by a complex

222 al expansion of specific tRNA synthetases in higher organisms is well documented.

223 which is essential for normal development in higher organisms, is one such macromolecular machine.

224 nal circuitry that takes years to develop in higher organisms, it also poses a major obstacle for CNS

225 es by plants suggested toxicological risk to higher organisms known to utilize macrophytes as a food

226 ortant for the interactions of bacteria with higher organisms - leading to rhizosphere colonization a

227 e presence of highly conserved paralogues in higher organisms led us to assess whether compensation b

228 ng in both lower organisms like bacteria and higher organisms like yeast, which allows them to prefer

229 PAK-family kinases in higher organisms may have similar functions.

230 fe-span extension by CR and suggest that, in higher organisms, multiple members of the Sir2 family ma

231 s is among the most fundamental processes of higher organism ontogenesis.

232 In higher organisms PAPS synthesis is catalyzed by a bifunc

233 one's own body, is a fundamental ability of higher organisms, playing a central role in many percept

234 These results indicate that Sir2 in higher organisms plays an essential role in both euchrom

235 titution of functionally effective mimics of higher organism PTMs.

236 ained and propagated within somatic cells of higher organisms, recent in vitro and in vivo evidence d

237 E-B unstructured C-terminal domain unique to higher organisms regulates DUE-B intermolecular binding.

238 Entrainment of circadian rhythms in higher organisms relies on light-sensing proteins that c

239 the circadian clock in Drosophila and other higher organisms relies on the quantification of rhythmi

240 Higher organisms rely on a closed cardiovascular circula

241 de novo pathway in bacteria and plants, most higher organisms rely on a salvage pathway that phosphor

242 t molecular mechanisms, both prokaryotes and higher organisms rely on programmed genetic variation to

243 f the large non-coding part of the genome in higher organisms remains poorly understood.

244 ole of the coagulation system in immunity in higher organisms remains unclear.

245 REVIEW Most higher organisms reproduce sexually, despite the automat

246 Thus, higher organisms require alternate modes of reducing the

247 Transcription in higher organisms requires spatiotemporal coordination of

248 Sulfation of all macromolecules in higher organisms requires the high-energy donor 3'-phosp

249 uent quantitative analysis of total RNA from higher organisms revealed varying levels and TET-indepen

250 r based on host defense peptides (HDPs) from higher organisms, show promising activity against human

251 In all higher organisms studied to date, related Group B Sox pr

252 this approach remains a major challenge for higher organisms such as humans.

253 ity has not yet been clearly demonstrated in higher organisms such as mammals.

254 ingle cell eukaryotes such as yeasts, and in higher organisms such as man.

255 y perceived that tissues were only formed by higher organisms such as plants and animals.

256 In higher organisms such as vertebrates, it is generally be

257 tingly, R(442) is conserved in most STATs in higher organisms, suggesting conservation of function.

258 he amino acid sequences of p67 from lower to higher organisms suggests that there is a progressive ad

259 e closely related to 2-Cys peroxiredoxins of higher organisms than to most other eubacterial AhpC pro

260 peptides are important defense compounds of higher organisms that can be used as therapeutic agents

261 tion is a post-translational modification of higher organisms that deiminates arginines in proteins a

262 Redundancy is common among phenotypes of higher organisms that experience low mutation rates and

263 Unlike the PKGs of higher organisms that have two cGMP binding sites in the

264 network of apoptotic pathways has evolved in higher organisms that possess homologs within each set o

265 a class of small cationic peptides found in higher organisms that serve as both antimicrobial and ce

266 tances, directly influence interactions with higher organisms, the broader physiological significance

267 Thus, as in higher organisms, the Drosophila nervous system is diffe

268 In higher organisms, the functions of many proteins are mod

269 disadvantages like notable toxicity against higher organisms, the high price, and low abundance of s

270 -surface receptors, muscle structure and, in higher organisms, the immune system.

271 of TyrRS directly controlled by tRNA(Tyr) in higher organisms, the NLS of lower eukaryotes was abando

272 In higher organisms, the phenotypic impacts of potentially

273 genetic pathways and pathway components with higher organisms, the study of its interaction with bact

274 s an integral role in calcium homeostasis in higher organisms through its actions in the intestine, k

275 Information on responses of higher organisms to climate change is dominated by event

276 nt a new class of genes that have evolved in higher organisms to govern the synthesis of highly speci

277 tic life cycle, as well as traits that allow higher organisms to survive rare environmental disasters

278 Particularly in higher organisms, transcription factors (TFs), microRNAs

279 ein degradative process that is activated in higher organisms under conditions of prolonged starvatio

280 llular apoptosis: why do the mitochondria of higher organisms, unlike their bacterial ancestors, use

281 espite what is known about apocarotenoids in higher organisms, very little is known about apocaroteno

282 hese postulates are valid for the MPC from a higher organism, we examined the size distributions of p

283 d feature prediction tools in the genomes of higher organisms, we evaluated their performance on a la

284 sulfate donor for sulfate ester formation in higher organisms, we have undertaken a kinetic character

285 , inspired by scaffold-directed signaling in higher organisms, we modularize prokaryotic signal trans

286 t composite TFBS elements, commonly found in higher organisms where two or more TFBSs form functional

287 n of replicating entities (molecules, cells, higher organisms), where evolutionary principles prevail

288 Phe37 exists only in higher organisms, whereas it is replaced by other residu

289 biosynthesis requires 10 enzymatic steps in higher organisms, while prokaryotes require an additiona

290 ted at the beginning of the fossil record of higher organisms, while the differences between the anci

291 How could this happen in higher organisms whose populations are small compared to

292 head: understanding the molecular biology of higher organisms will require revealing all proteins (Pr

293 teractions between vibrios, (micro)algae and higher organisms, with major ecological and practical im