ライフサイエンスコーパス: highlight

1 etabolism of sugars and stress response were highlighted.

2 cribed, and three important applications are highlighted.

3 vision loss in diabetic retinopathy (DR) are highlighted.

4 e and dose in dose-response relationships is highlighted.

5 e control of antibiotic residues in food are highlighted.

6 homeostasis in the GI tract during GVHD are highlighted.

7 of combined etiologies on anemia severity is highlighted.

8 We highlight 16 genes based on expression quantitative trai

9 Together, these findings highlight a biological link between inner ear dysfunctio

10 The results highlight a charge transfer transition that leads to cha

11 al study that focuses on temperate drylands, highlight a distinct fate for these highly populated are

12 Taken together, our findings highlight a pivotal link between an epigenetic regulator

13 These results highlight a plausible stepwise evolutionary trajectory f

14 We highlight a population of CRMs that are continuously occ

15 Y6E promotes HIV-1 entry and replication and highlight a positive regulatory role of IFN-induced prot

16 Our findings highlight a possible asymmetry in protein-ligand associa

17 Overall, the results highlight a potential link between cytosolic Ca(2+) sign

18 ny but not all of the membrane molecules and highlight a powerful experimental approach to decipher s

19 Our findings highlight a role for keratinocytes and their interplay w

20 a maintenance factor in the adult brain, and highlight a trophic pathway that can be targeted to amel

21 Furthermore, our findings may highlight a unique mechanism for how HCMV avoids the ant

22 xpressing upd3 and rescued by deleting upd3, highlighting a crucial role for this cytokine.

23 structures were determined computationally, highlighting a delicate balance between the extent of po

24 enerations of RAFi, vemurafenib and PLX8394, highlighting a distinct responsiveness of CRAF fusions t

25 ns can fail to protect for opposite reasons, highlighting a major challenge in tuberculosis vaccine d

26 argely TL-dependent, we resolve the paradox, highlighting a regulatory role of telomeres in cancer.

27 We present here a summary of meeting highlights, a series of "success factors" that will benc

28 Our findings highlight an important novel function of VitD demonstrat

29 ng therapies for frontotemporal dementia and highlight an important role for neuron-derived progranul

30 eology to (i) catch this phenomenon and (ii) highlight an unexpected consequence: the self-diffusion

31 r CDI experienced greater HO-CDI rates; this highlights an important adverse effect of the PIP/TAZO s

32 Our study highlights an important innate immune signalling pathway

33 pics in the management of these disorders to highlight areas of importance for future clinical trials

34 contributing to pulmonary carcinogenesis and highlight ASXL3 as a novel candidate target for SCLC the

35 es between predation in buffer and serum and highlights both the potential and limitations of B. bact

36 This study highlights broad non-compliance of a range of popular pe

37 l to consider a multifactorial approach that highlights building trust in vaccinators, providing fact

38 The synthesis is highlighted by an enzyme-catalyzed reaction to access 3,

39 Utility is highlighted by gram-scale preparation of representative

40 The interface region is highlighted by interactions that disrupt the cubic symme

41 eral usefulness of the docking algorithm was highlighted by redocking of peptide toxins to two ion ch

42 ials in cancer patients, and our experiments highlight concerns on the homeostasis and regenerative c

43 ld of functional and artificial amyloids and highlight connections between protein/peptide folding, u

44 pressed miRNAs, spearman correlation testing highlighted correlation of hsa-miR-642a-3p, hsa-miR-4459

45 s near high endothelial venules, the results highlight critical roles of innate/inflammatory response

46 vitamins, and biological agents with AIT is highlighting current advances.

47 These methods highlight detailed insights in the structure and dynamic

48 Our findings highlight developmentally regulated changes in mitotic b

49 These results highlight differences in the transfer of favorable gene

50 arned food reward-driven responding, thereby highlighting endocrine and neuropeptidergic signaling in

51 sponse strategies activated by Nrf2, we also highlight endogenous coping responses that might be ther

52 em, comprised of liver, heart, and lung, and highlight examples of inter-organ responses to drug admi

53 tructure and speeds of sound is presented by highlighting existing correlation and evaluative methods

54 abolic and developmental regulator ESRRA was highlighted for an especially early and important regula

55 Our study highlights forensic services as a central component of t

56 for portrayal of demographic inferences and highlight genetic variation indicative of selection at s

57 d that BPAF is more potent than BPA, further highlighting health concerns regarding the use of BPA al

58 1, to circumvent ineffective erythropoiesis, highlighting heme and translation in the regulation of e

59 life viral disease and asthma-like features, highlighting HMGB1 as a possible novel therapeutic targe

60 atocyte transdifferentiation; moreover, they highlight HOTAIR as a crucial player in the Snail-mediat

61 We also highlight how further improvements to these exciting tec

62 regarding PSGL-1 structure and function and highlight how it may act as an immune checkpoint inhibit

63 These results highlight how nanoscale changes can induce reactivity in

64 levant to drug response and immunity, and we highlight how such improvements enable a greater underst

65 al characteristics of CRISPR-Cas systems and highlight how these features can be used in industrial s

66 k this to the TRIM21 effector mechanism, and highlight how this work is exposing the previously restr

67 elationship between ambivalence and conflict highlights how both extremely peaceful and extremely con

68 tructural brain alterations in the disorder, highlighting impediments to progress, recent development

69 s on the quality of footprint predictions to highlight important considerations when conducting footp

70 Recent studies, highlighted in this review, started to interconnect PI3K

71 As highlighted in this review, the exact nature and extent

72 nd porphyrin-based nanostructures, have been highlighted in this review.

73 field by showing a diverse number of recent highlights, including out-of-equilibrium self-assembly,

74 articularly major depressive disorder (MDD), highlighting insights from positron emission tomography

75 The present findings highlight insular disintegration (ie, compromised salien

76 The authors highlight irritability and callous behavior as two core

77 fort to condense the recent research on l-Th highlighting its biological resource, plausible role in

78 le transduction following IP administration, highlighting its potential as a new muscle-targeting vec

79 iation pathways in autoreactive CD4 T cells, highlighting its potential as a therapeutic target for t

80 ed motifs in core sequences, we were able to highlight key conserved residues driving essential eleme

81 These results highlight key genes, biological processes, and cell type

82 ides a resource for the scientific community highlighting key paradigms of the type I IFN response.

83 This article highlights key lessons learned during the introduction o

84 for measurement of ongoing transmission, and highlight knowledge gaps that must be addressed.

85 egration in spatial optimization modeling we highlight lands and waters that together achieve joint c

86 pid progress within in the field, while also highlighting limitations of current methods.

87 This review seeks to highlight multiple cheminformatic approaches in drug dis

88 yses and wet bench experiments, our findings highlight new biological pathways for blood pressure reg

89 by self-propagating gene drive technologies, highlight new gene drive designs that might achieve bett

90 nabling technology are critically discussed, highlighting new opportunities, problems to be solved an

91 ensitivities to a mutation in fgf8a Our data highlight novel aspects of SHF, OFT and HM development i

92 These loci highlight novel biological functions, including response

93 his is thought to have evolutionary origins, highlighting objects likely to provide benefit in the fu

94 This report presents highlights of this working group review and a summary of

95 provides insights toward the cell of origin, highlighting oligodendroglial lineage genes, and reveals

96 lds of computational and systems biology and highlight opportunities for researchers to use big data

97 ions can be used to assess ligandability and highlight opportunities for successful lead and tool dis

98 common traits shared by most groups and also highlights particular features in lungfishes different f

99 remains unknown whether L1 expression simply highlights piRNA deficiency or actually drives the germ-

100 In-silico analysis further highlighted potential association of select claudins, mo

101 t crystal structure and in vitro experiments highlighted potential residues mediating the AP-1/Arf1 i

102 Moreover, we highlight recent advancement in functionalizing gold by

103 Here, we highlight recent advances in our understanding of how th

104 Finally, we briefly highlight recent applications to illustrate future direc

105 We highlight recent empirical studies of transgenerational

106 In this review, we highlight recent progress (2008-2016) in infrared reflec

107 In this review we highlight recent studies that advance the knowledge and

108 es in these three aspects of cancer biology, highlighting recent advances and potential limitations.

109 ponatremia, comparing the two guidelines and highlighting recent developments.

110 equence variation in modern elite germplasm, highlighting regions vulnerable to genetic erosion.

111 We highlight research that reveals to what extent convergen

112 rovide mechanistic insight into RNR biology, highlighting RRM2B as a hypoxic-specific, anti-cancer th

113 that underlie external task engagement, and highlight selective changes in brain connectivity suppor

114 We highlight several plant natural products that are either

115 Taken together, these data highlight several potential biomarkers that can be used

116 We conclude by highlighting shared themes that may be key for advancing

117 Through this process, we highlight some of the more controversial aspects of cari

118 This review will highlight some recent novel cardiovascular magnetic reso

119 In particular, it highlights some of the critical roles and functions of a

120 changes reminiscent of dedifferentiation and highlight SOX5 as a regulator of beta-cell phenotype and

121 90 distinct in vitro conditions by RB-TnSeq, highlighting specific metabolic functions associated wit

122 In this Review, we highlight synergistic biological pathways through which

123 Our findings highlight TBX2 as a novel therapeutic target upstream of

124 We also highlight technological developments in 2D IR that conti

125 sights into the activation of IL-36gamma and highlight that cathepsin S-mediated activation of IL-36g

126 Overall, these differences highlight that changes in infant formula composition imp

127 We highlight that correct identification of cancer in indet

128 Thus, the findings highlight that in addition to tanning bed avoidance, it

129 nhancer RNAs (eRNAs) in early elongation and highlight that transcriptional enhancers might modulate

130 These results highlighted that gastrointestinal digestion may substant

131 Genetic analysis highlighted that Italian swine IDVs are closely related

132 Results highlighted that KuQs are highly active toward the analy

133 ies, and transition metal ion sequestration, highlighting that the immune response is dominated by in

134 Furthermore, these results highlight the advantage of the use of class II tetramers

135 These experiments also highlight the applicability of RT-QuIC to identify poten

136 These findings highlight the capacity of DA neurons to act as metabolic

137 Together, our results highlight the chemical versatility of artificial aldolas

138 We also highlight the complex role of the necroptotic pathway in

139 In aggregate, our findings highlight the complexity of the genetic regulation of pu

140 of NoV proteins during virus replication and highlight the conserved properties of the NoV NS3 protei

141 Our experiments highlight the contingent nature of predator-prey interac

142 Our data highlight the contribution of CD69 as a nonredundant key

143 ld-changes between different cell-types, and highlight the contribution of post-transcriptional regul

144 ere we untangle some of these intricacies to highlight the contributions of inflammation, angiogenesi

145 Our results also highlight the critical role played by antigen density in

146 axis in myelopoiesis and leukemogenesis and highlight the critical roles of METTL14 and m(6)A modifi

147 using a primitive method without BSSVS, and highlight the differences in phylogenies created by each

148 inhibition of prion-seeded amyloid formation highlight the diverse roles lipid constituents may play

149 id domains or "lipid rafts." Recent findings highlight the dynamic nature of such domains and the key

150 These results highlight the fact that geographic area and environmenta

151 canonical NF-kappaB in Tconv and Treg cells highlight the functional plasticity of the NF-kappaB sig

152 uce and maintain the dysfunctional state and highlight the heterogeneity of CD8(+) T-cell phenotypes

153 -resolution microscopy and flow cytometry to highlight the heterogeneity of drug activity within tumo

154 The results highlight the importance and functional consequence of t

155 The discrepancies between models highlight the importance for policy makers to carefully

156 These results highlight the importance of choosing cells lacking endog

157 eation of avian-specific traits, and further highlight the importance of cis-regulatory rewiring duri

158 These methods highlight the importance of computational techniques in

159 Our results highlight the importance of kinesin-3 based axonal trans

160 These studies highlight the importance of multiscale imaging of HIV-1-

161 utational models reproduce these results and highlight the importance of neurons coding feature value

162 Collectively, these studies highlight the importance of nucleobase desolvation as a

163 pendent versus homeostatic regeneration, and highlight the importance of postmitotic cell growth in g

164 These findings highlight the importance of prompt diagnosis, care engag

165 Taken together, our results highlight the importance of RALY as an indirect regulato

166 Our data not only highlight the importance of regulating the epigenetic la

167 These results highlight the importance of seagrass ecosystems to the h

168 These results highlight the importance of sequence context for alt-EJ

169 These results highlight the importance of soil- and leaf-P in defining

170 Not only do our results highlight the importance of the gut microbiome in honeyb

171 sitive impacts on housing stability and STIs highlight the importance of the supportive housing progr

172 These results highlight the important role of C. difficile flagella in

173 Our results highlight the intimate relation between attentional mech

174 In this review, we highlight the key aspects of the 2016 update with partic

175 In this Perspective, we highlight the key contributions of these synthetic appro

176 ependency of dispersion are discussed, which highlight the major flaws in parametrization of existing

177 Our findings highlight the molecular and anatomical heterogeneity of

178 quality and health cobenefits of biochar use highlight the need for an improved understanding of bioc

179 ing GPP under current and future climate; we highlight the need for experimental studies to identify

180 Our findings highlight the need for further analysis of the T cells i

181 acquired drug resistance are concerning and highlight the need for longer-term follow-up studies.

182 Our results highlight the need for more detailed studies of tree phy

183 t in treatment delay during the study period highlight the need for standardized diagnostic routines

184 D24(-) cells can remain aggressive, and they highlight the need to consider nucCD24 in both fundament

185 gions of tidal decrease and/or amplification highlight the non-linear response to sea-level variation

186 d be a useful tool for the olive industry to highlight the nutritional quality of EVOOs and improve t

187 Overall, our results highlight the overlapping timescales and the interplay o

188 Our analyses highlight the performance characteristics of these workf

189 ytokine recognition by the IL-10R family and highlight the plasticity of type III interferon signalin

190 These data highlight the potential benefits of BACE inhibition for

191 We highlight the potential challenges associated with progr

192 These results highlight the potential for "big data" techniques to pro

193 Taken together, the data highlight the potential impact of that small RNAs and hi

194 Our results highlight the potential of gene expression data to quant

195 tivity of individual OPCs and more generally highlight the potential of traditional Chinese medicine-

196 These results highlight the power of large-scale proteomics to identif

197 y for patients with F3 fibrosis; our results highlight the promise of bariatric surgery for treating

198 r conditions of sustained BAT activation and highlight the relevance of cholesterol metabolism by the

199 Altogether, these advances highlight the rich potential of nanoplasmonic sensors an

200 The findings highlight the richness of polar topologies possible in u

201 These data highlight the role of ctDNA as a minimally invasive mole

202 Our calculations highlight the role of differential distortion of the anh

203 hrony in key nonverbal social behaviors, and highlight the role of human attachment in providing a te

204 These findings highlight the role of the inhibitory microenvironment an

205 These findings highlight the role of the transamidase complex in the de

206 c modification to mammalian neurogenesis and highlight the role of this nutrient-sensing pathway in d

207 therefore be avoided, and two recent papers highlight the roles of p53, senescence, and the immune s

208 These observations highlight the serotype-dependent heterogeneity of the ca

209 These results highlight the significance of the relative contributions

210 These data highlight the unique contributions CHY4 and MMSD make to

211 These findings highlight the unknown complexity of telomerase structura

212 Moreover, we highlighted the cross-talk between nitric oxide and H2S

213 ellular basis of transcriptional changes and highlighted the dramatic acceleration of development in

214 This study highlighted the fact that surfactant precipitation can b

215 Recent studies have highlighted the importance of such metabolic regulation

216 Staff highlighted the importance of training, but staff traini

217 here, the findings presented at the meeting highlighted the important contributions of TGFbeta famil

218 te with protection against dengue virus have highlighted the need for a human DENV challenge model to

219 disrupt PD-L1-mediated tumour tolerance has highlighted the need to understand the molecular regulat

220 Additionally, the 2009 IAV pandemics highlighted the role of pigs in the emergence of IAVs wi

221 ynthetic analysis of dibenz[c,e]azepines has highlighted the use of imine reductase (IRED) and omega-

222 scopy resulted in an increase in resolution, highlighting the advantages in using a smaller, brighter

223 rom DSS-induced colitis than curcumin alone, highlighting the anti-inflammatory potential of turmeric

224 e kinome, with and without known substrates, highlighting the applicability of the method.

225 ath to successful clinical implementation by highlighting the application of chimeric antigen recepto

226 h subsequent post-transcriptional modulation highlighting the complexity of the processes involved in

227 r stop of therapy impaired immune tolerance, highlighting the dependence of the therapy-induced toler

228 to DNA and RNA molecules have been reported, highlighting the diverse roles that proteinaceous solven

229 or the K. marmoratus South Korea (SK) strain highlighting the diversity and distribution of transposa

230 om accumulation of unidentified suppressors, highlighting the importance and power of strain validati

231 roscopic mechanism of the phase transitions, highlighting the importance of cooperative multiscale pr

232 baseline parasympathetic tone respectively, highlighting the importance of individual neural and aut

233 alling promotes inflammatory ILC2 responses, highlighting the importance of neuro-immune crosstalk in

234 horylation also affected neuronal migration, highlighting the importance of tightly regulated CAMK2 a

235 We review here recent advances highlighting the interplay between epigenetics, genetics

236 SYNTHESIS: We identified four issues highlighting the key areas of ethical tension central to

237 of previously unseen features are reported, highlighting the local interplay between ordered and dis

238 esents a nutrient reservoir for tumour cells highlighting the metabolic flexibility of this cancer.

239 ith a CI defect of Mendelian origins, whilst highlighting the necessity of complete mitochondrial gen

240 es as a possible risk factor for stillbirth, highlighting the need for better skilled care during del

241 unced in adolescents than in young children, highlighting the need for raising public health awarenes

242 model NiAz system and the native ACS enzyme, highlighting the potential for related reactivity in thi

243 s against tumors, and discuss recent studies highlighting the potential of combination therapies recr

244 ferent analytical instruments in this field, highlighting the research needed for future focus.

245 e a revised clinical pathway for management, highlighting the role of genetic testing, a detailed ped

246 Yet, empirical evidence highlighting the sensitivity of ancient ice sheets to vo

247 Highlighting the significance of this mechanism, we foun

248 thelial cell infection for clinical disease, highlighting the spread to epithelia as an attractive ta

249 cinogenic role of the microbiota, as well as highlighting the therapeutic potential of microorganisms

250 The review also highlights the benefit of combining experimental and the

251 This study highlights the breadth of conditions influencing the bio

252 Emerging research highlights the complex interrelationships between sleep-

253 spectrum as well as its genetic etiology and highlights the complexity of the spliceosomal gene netwo

254 grees with our previous genetic analysis and highlights the consequences of redundancy and synergy du

255 Our review highlights the contrast between the abundance of insight

256 hich obliquity prevails over precession, and highlights the decisive role of astronomically forced "M

257 for release of the inactivation domain, and highlights the functional specialization of channel doma

258 Our comparative epidemiological approach highlights the heterogeneity among polio transmission de

259 sity-ecosystem variability relationships and highlights the importance of conserving regional species

260 long-term temperature dependence of GPP, and highlights the importance of considering physiological,

261 This analysis highlights the importance of considering the legacy of p

262 Our study highlights the importance of considering the packing whe

263 pic network model (an elastic network model) highlights the importance of flexibility in the entrance

264 Our study highlights the importance of lifelong monitoring of card

265 This finding highlights the importance of macrocyclization in combina

266 prevalence of pathogenic CNVs in this study highlights the importance of microarray analysis in adul

267 in neuronal saltatory migration in vivo and highlights the importance of MT flexibility in N-C coupl

268 This highlights the importance of selecting from both chemo-

269 Thus, our study highlights the importance of SENP8 in maintaining proper

270 e the predicted rate enhancements, our study highlights the importance of the atomistic and chemical

271 composition of cultured CD11c(+) cells, and highlights the important role of SWAP-70 in Cer dynamics

272 This study highlights the influence of posttranslational modificati

273 a prototypical heavy-fermion superconductor highlights the interrelation of nematicity and unconvent

274 high prevalence of IDH1 mutations in glioma highlights the need for brain-penetrant IDH1 mutant-sele

275 ble explanation for the observed pattern and highlights the need of better understanding human mobili

276 The growing elderly population worldwide highlights the need to understand how aging promotes CVD

277 ce pathways with that of emerging mechanisms highlights the overall complexity of GBM treatment resis

278 Furthermore, this study also highlights the overall transcriptomic control of the pla

279 This study highlights the poor representation of Arctic photosynthe

280 This finding highlights the possibility that the bioactivity of such

281 ation of effects over time for many outcomes highlights the potential for resilience in children who

282 This work highlights the power of (1)H photo-CIDNP for characteriz

283 This discovery highlights the role that intracellular localization play

284 Our phenotypic characterization highlights the suitability of iPSC-derived cortical neur

285 g of the gut-hormone glucagon-like peptide-1 highlights the therapeutic potential of gut-derived sign

286 The present review highlights the therapeutic potential of targeting B7-H4.

287 YAP reprograms glucose metabolism, but also highlights the therapeutic potential of targeting YAP-BC

288 Our study highlights the urgency of determining specific managemen

289 The target article highlights the utility of new technology to study sign l

290 We call them swarmalators, to highlight their dual character.

291 eduction in foam degradation of the proteins highlights their use in beverages where the foam is an i

292 onships of late Palaeozoic actinopterygians, highlights this part of the fossil record as a major fro

293 ric regression misspecification; our results highlight TMLE's property of double robustness.

294 Highlighted topics include how solution-processing techn

295 cules is unprecedented among eukaryotes, and highlights unexpected variation in plastid genome archit

296 The results also highlight unique as well as conserved elements in the PA

297 Our findings highlight unique immunological processes leading to BOS

298 ize their complementary functionalities, and highlight which tool is best equipped for specific tasks

299 regarding terpene metabolic engineering are highlighted, with a special focus on tobacco (Nicotiana

300 imination of historical Pb input phases, and highlight within-estuary mixing and supply of reworked,