ライフサイエンスコーパス: highly structured

1 o MM-1 in a specific manner without becoming highly structured.

2 cells in these dimensions was nonuniform and highly structured.

3 for the mRNA target even in a region that is highly structured.

4 d visual neuropils of the praying mantis are highly structured.

5 urvive in an environment that is diverse yet highly structured.

6 This implies that the G-matrix will be highly structured.

7 Ecosystems are highly structured.

8 n give rise to communities that are socially highly structured.

9 possibility that this fusion peptide may be highly structured.

10 ndary and tertiary structure contacts in the highly structured 16S rRNA.

11 In mammalian selenoprotein mRNAs, the highly structured 3' UTR contains selenocysteine inserti

12 is-acting RNA elements mainly located in the highly structured 5' and 3' untranslated regions.

13 ntron removal and the presence of a long and highly structured 5' untranslated region that inhibits e

14 enger RNA selectivity is proposed to reflect highly structured 5' untranslated regions that depend st

15 nomes occurs via internal ribosomal entry at highly structured 5' untranslated regions.

16 f a group of mRNAs that possesses a long and highly structured 5'-untranslated region (UTR) containin

17 that translation of MS, which has a long and highly structured 5'-untranslated region, is initiated f

18 ith stimulation of translation of mRNAs with highly structured 5'-untranslated regions.

19 lting in repressed translation of mRNAs with highly structured 5'-untranslated regions.

20 bl mRNA was discovered to possess a long and highly structured 5'-UTR containing a 12-pyrimidine TOP

21 These mRNAs possess highly structured 5'-UTRs that impede ribosome recruitme

22 fficient 48S complex formation on mRNAs with highly structured 5'UTRs, and that this process requires

23 the Deep Impact encounter returned detailed, highly structured, 5- to 35-micrometer spectra of the ej

24 The highly structured (64% GC) covalently closed circular (C

25 linary rehabilitation team, but incorporates highly structured activity-based therapies, pharmacology

26 Resident among the highly structured adult nervous system, a few cells, ref

27 y process is highlighted by the inability of highly structured alpha-globins to undergo ordered oligo

28 lded microtubule-associated protein Tau to a highly structured amyloid fibril underlies human Tauopat

29 compassing most of the central beta-sheet is highly structured and alpha-helix 3, which is partially

30 point for folding under native conditions is highly structured and already poised to adopt the native

31 ctions to transform the nucleus and assemble highly structured and compartmentalized viral genome dom

32 some entry sites (IRESes) of viral mRNAs are highly structured and comprise several hundred nucleotid

33 on function AF-1 and DNA binding domains, is highly structured and contributes significantly to the o

34 esults indicate that DB340 binds to RRE in a highly structured and cooperative complex at a 2:1 DB340

35 ons of neurons whose electrical activity was highly structured and correlated with the images on the

36 (BBM) of intestinal epithelial cells forms a highly structured and dynamic environmental interface th

37 rocircuits in which synaptic connectivity is highly structured and excitatory neurons form subnetwork

38 o TNPO3 architecture and indicate that it is highly structured and exists in a monomer-dimer equilibr

39 dation is surprising, since SsrA RNA is both highly structured and highly abundant.

40 pe 4.3.1), the global S. Typhi population is highly structured and includes dozens of subclades that

41 -untranslated region that is predicted to be highly structured and is important for regulating the ra

42 Four different, both highly structured and nonstructured downstream GC-rich s

43 loop portion of the 690 hairpin folds into a highly structured and novel conformation.

44 calize PrP(C) expression in a tissue that is highly structured and of crucial behavioral importance t

45 by the Cluster mission that clearly show the highly structured and periodic pattern of these waves.

46 Furthermore, these model organisms are highly structured and require correction for population

47 nd then by organizing protein and DNA into a highly structured and stable nucleoprotein 'synaptic' co

48 IMPC mouse clinics worldwide follow rigorous highly structured and standardized protocols for the exp

49 lding and suggests that thiopeptoids will be highly structured and therefore potentially useful as th

50 he untranslated region (UTR) predicted to be highly structured and to encode a small ORF.

51 own by circular dichroism spectroscopy to be highly structured and to exhibit about 25% sequence iden

52 ner radiation belt are organized in regular, highly structured and unexpected 'zebra stripes', even w

53 re, the temporal pattern of EOD intervals is highly structured and varies depending on the behavioral

54 dues 22-421, that is proteolytically stable, highly structured, and able to fully support ERAD in viv

55 ully solvent-exposed and mobile, the core is highly structured, and the C-termini are flexible but re

56 Thus, the second SID, SID2, is highly structured, and this alpha helix (helix 2(58-72))

57 The data also clearly show that highly structured ANME-2/Desulfosarcina consortia are no

58 application of tumor down-staging requires a highly structured approach using a treatment protocol th

59 , we present evidence demonstrating that the highly structured approximately 160-nucleotide adenovira

60 x interactions, which ultimately mediate the highly structured arrangement of cells on a basement mem

61 t twitches are not produced randomly but are highly structured at multiple timescales.

62 at the site of the ciliary dilation (CD), a highly structured axonemal inclusion of hitherto unknown

63 ' turn of CD4 on this tryptophan "stem" are highly structured beta-hairpins in water.

64 how for the first time that pneumococci form highly structured biofilm communities during colonizatio

65 discuss these points we use microbial mats - highly-structured biofilm communities living under sharp

66 GroEL-polypeptide complexes assembled into a highly structured but inactive 85.5-kDa alpha beta dimer

67 These data are often highly structured, but that structure is hidden in a com

68 which hydrolyzes only one peptide bond in a highly structured calcium-binding domain of desmoglein 1

69 procedures for quantifying small amounts of highly structured cDNAs and their RNA templates.

70 VAI consists of an apical stem-loop, a highly structured central domain, and a terminal stem.

71 ntains three domains: an apical stem-loop, a highly structured central domain, and a terminal stem.

72 The resulting highly structured ceramics could have applications in ar

73 se results suggest that HCR-1 functions in a highly structured chromatin environment requiring a comp

74 The highly structured, cis-encoded RNA elements known as rib

75 At neutral pH, DOBMP forms highly structured, clustered dispersions 500 nm in size.

76 In addition, NC destabilizes the highly structured complementary trans-activation respons

77 ectable binding to duplex DNA, RusA formed a highly structured complex with a synthetic Holliday junc

78 customized chaperones, with which they form highly structured complexes.

79 elegans neuromuscular junctions (NMJs) were highly structured, composed of building units forming ba

80 uel cells, its near-surface layer exhibits a highly structured compositional oscillation in the outer

81 which four are proline, giving the peptide a highly structured conformation.

82 The specific, highly structured connectivity rules suggest that these

83 in residues critical to hormone binding were highly structured, constraining potential allosteric mec

84 ligands and contain iron centers embedded in highly structured coordination sites defined by two bulk

85 ions: an unstructured N terminus (1-6) and a highly structured core (7-23).

86 brate TERs are thought to share a conserved, highly structured core domain that includes the templati

87 We show that a highly structured course design, based on daily and week

88 of the subunit ectodomain, which contains a highly structured cysteine-rich repeat region.

89 view about the molecule, with citations, and highly structured data for bioinformatics interrogation,

90 eway Molecule Pages (SGMP) database provides highly structured data on proteins which exist in differ

91 ted, ranging from simple data collections to highly structured databases.

92 Bivalent shells possess two highly structured defects, which are composed of a numbe

93 in the NMR spectrum are consistent with the highly structured dimeric native state of the protein.

94 Tetrahymena thermophila stem-loop IV shows a highly structured distal stem-loop linked to a conformat

95 The structure of one of the toxins reveals a highly structured, disulfide-rich core and a structurall

96 en insensitivity syndrome are located in the highly structured DNA and ligand binding domains.

97 Here, we show that replication of a highly structured DNA in the presence of a unique set of

98 been ascribed to NS5A that is composed of a highly structured domain 1 (D1), as well as two intrinsi

99 An array of highly structured domains that function as metabolite-re

100 iting Enriched Regions (EERs), indicative of highly structured dsRNA.

101 ting and storing human genomic variations in highly structured, easily accessible databases.

102 The presence of highly structured, easily evoked behavioral systems offe

103 This highly structured element induces valylation of the vira

104 es a protein, Rev, which binds to a complex, highly structured element within viral RNA, the Rev resp

105 e extragenic palindromic (REP) sequences are highly structured elements found downstream of approxima

106 ome the translation-inhibitory effect of the highly structured encapsidation signal and other replica

107 Highly structured environments might offer clues.

108 re, we present a nucleotide-level model of a highly structured equilibrium folding intermediate of th

109 ensemble of the encapsulated beta-hairpin is highly structured even at substantially elevated tempera

110 that activity in macaque auditory cortex is highly structured even in the absence of sensory stimuli

111 The plasma is highly structured-exhibiting sharp breaks, smooth variat

112 rom an intrinsically disordered monomer to a highly structured fiber.

113 rix uncovered by this procedure consisted of highly structured fibers, connected to the nuclear lamin

114 Highly structured FLN spectra obtained at 4.2 K allowed

115 Double emulsions are highly structured fluids consisting of emulsion drops th

116 Each channel involves a stable, highly structured folding intermediate whose kinetic pro

117 oDB, GUS (Genomics Unified Schema) employs a highly structured format to accommodate the diverse data

118 ) and RNA Abundance Database (RAD)] employ a highly structured format to accommodate the diverse data

119 These conotoxins fold into small highly structured frameworks, allowing them to potently

120 f rhinophores, tentacles, and mouth showed a highly structured glomerular organization of 5-HT-IR fib

121 should observe forms of reciprocity even in highly structured group environments in which reciprocit

122 Highly structured group intervention did not outperform

123 They can also produce highly structured, high-quality data that could be exami

124 , which infer that such targets will produce highly structured hot electron transport.

125 ntaneous activity in cortical populations is highly structured in both space and time, (b) the spatio

126 Sensory signals are highly structured in both space and time.

127 tudies show that long-range correlations are highly structured in spatiotemporal patterns, known as r

128 s compartment, the matrix, is bounded by the highly structured inner membrane, which in turn is bound

129 ates were randomly assigned to view either a highly structured instructional videotape about the cons

130 atitis C virus (HCV) RNA is initiated from a highly structured internal ribosomal entry site (IRES) i

131 op V attenuation determinants lie within the highly structured internal ribosome entry site.

132 tions in low-resource settings have employed highly structured interventions delivered by non-profess

133 and in absence of any task, is astonishingly highly structured into spatiotemporal patterns.

134 These signals need to be integrated through highly structured intracellular networks to ensure coher

135 FMDV IRES is phylogenetically conserved and highly structured; it contains four-way junctions where

136 llic systems is to exploit the intricate and highly structured ligands found in natural metalloprotei

137 xplain how long-range correlations flow from highly structured linguistic levels down to the building

138 , the ability of ceramide to localize within highly structured lipid microdomains (rafts) and activat

139 Pharmacological disruption of highly structured lipid microdomains resulted in abrogat

140 This highly structured loop contained between helices two and

141 spatial frequency tuning was organized into highly structured maps that remained consistent across t

142 in nanotechnology to direct the assembly of highly structured materials with specific nanoscale feat

143 Bone is a complex highly structured mechanically active 3D tissue composed

144 bacterial cells and further development into highly structured microcolonies.

145 sition state, the antibody pocket provides a highly structured microenvironment for the reaction in w

146 Plant cells create highly structured microtubule arrays at the cell cortex

147 These natural networks are highly structured, modular, coherent, and nested to some

148 mperatures, the rpoH gene transcript forms a highly structured mRNA containing several three-way junc

149 interaction to modulate translation of their highly structured mRNA.

150 is often due to the increased propensity of highly structured mRNAs to be degraded and/or processed

151 The optical spectrum of this NC displayed highly structured multiple absorption peaks.

152 se range of ecosystems are often composed of highly structured multispecies communities.

153 sting of a relatively amorphous matrix and a highly structured network of microfibrils embedded in th

154 Instead, these are highly structured networks held together by receptor dim

155 Behaviour is governed by activity in highly structured neural circuits.

156 Here we show highly structured neuronal encoding of vowel articulatio

157 These highly structured non-coding RNAs of approximately 117 n

158 ymes are catalytically competent examples of highly structured noncoding RNAs, which are ubiquitous i

159 biology and engineering and emphasizes, (i) highly structured, nongeneric, self-dissimilar internal

160 The 5' end of the viral genome contains a highly structured nontranslated region (5'NTR) which fol

161 Strand transfer in highly structured nucleic acid species from the U3 3' lo

162 completely unable to stimulate annealing of highly structured nucleic acids.

163 uences of histones H3 and H4 extend from the highly structured nucleosome core.

164 assays were completed with unstructured and highly structured oligonucleotide complements.

165 of class A beta-lactamases: enzymes that are highly structured on the ps-ns timescale, with important

166 of HDX simulations in a three-state system (highly structured, partially unstructured, and fully uns

167 ccessible chromatin (ATAC-seq), we observe a highly structured pattern of DNA fragment lengths and po

168 Highly structured, peptide antagonists of the interactio

169 enomous cone snails (genus Conus) use small, highly structured peptides (conotoxins) for interacting

170 Ph)Pz]Cu}(3) compound exhibits an additional highly structured phosphorescence with a vibronic struct

171 stry correction, GWAS remains challenging in highly structured populations, such as S. cerevisiae.

172 f association mapping in barley, even within highly structured populations.

173 ce selectively stimulates the translation of highly structured proliferation and tumor-promoting mRNA

174 pper-zinc superoxide dismutase-1 (SOD1) is a highly structured protein and, a priori, one of the leas

175 ibrillation of this exceptionally stable and highly structured protein under mild, physiologically ac

176 involve somatosensory cortical neurons with highly structured receptive fields: these cortical popul

177 nate is 0.46 A for the backbone atoms in the highly structured region and 0.88 A along the entire bac

178 ments reveal that Hsp90 binds to a specific, highly structured region of Delta131Delta.

179 were more frequent but were restricted to a highly structured region of the reporter.

180 sociate with the telomerase RNA depends on a highly structured region rather than specific sequence e

181 uding a shifty heptanucleotide followed by a highly structured region.

182 slated region of poliovirus RNA contains two highly structured regions, the cloverleaf (CL) and the i

183 Riboswitches represent a family of highly structured regulatory elements found primarily in

184 Highly structured retinal waves were first observed at E

185 zinc finger structures are needed to unfold highly structured RNA and DNA strand transfer intermedia

186 ecific metal ion interactions in this large, highly structured RNA are poorly understood.

187 Analysis of PTE by SHAPE revealed a highly structured RNA comprising seven stem-loop structu

188 ichroism spectra indicated the presence of a highly structured RNA conformation with a significant am

189 CV) internal ribosome entry site (IRES) is a highly structured RNA element that directs cap-independe

190 irus encodes virus-associated RNA I (VAI), a highly structured RNA inhibitor that binds PKR but fails

191 ocess Rev oligomerizes in association with a highly structured RNA motif, the Rev response element.

192 Ribozymes are highly structured RNA sequences that can be tailored to

193 DAD2 and Staufen1 display higher affinity to highly structured RNA substrates.

194 RNase R readily degrades highly structured RNA, whereas its paralogue, RNase II,

195 lease that has the unusual ability to digest highly structured RNA.

196 5' hydrolytic exoribonuclease able to digest highly structured RNA.

197 Barr virus (EBV) EBER transcripts are small, highly structured RNAs able to bind to and inhibit activ

198 ins accelerate folding and rearrangements of highly structured RNAs and RNA-protein complexes (RNPs)

199 A-binding motifs (dsRBMs) and interacts with highly structured RNAs as well as the dsRNA-activated pr

200 lding transitions involving large regions of highly structured RNAs can proceed in a concerted fashio

201 SHAPE-directed modeling of these highly structured RNAs gave an overall false negative ra

202 ture formation event and suggest that large, highly structured RNAs may have local regions that are m

203 and have developed conditions for purifying highly structured RNAs on a modified tube-gel apparatus.

204 Many lupus autoantigens contain small, highly structured RNAs, and studies have shown that the

205 bonucleases, RNase R can efficiently degrade highly structured RNAs, but the mechanism by which this

206 inger 1 (N-terminal) being more important on highly structured RNAs.

207 o mediate specific interactions with various highly structured RNAs.

208 of spurious association expected to occur in highly structured samples.

209 , folds into a conformation containing three highly structured segments, consisting of contiguous seq

210 uctures remain ill-defined, other than being highly structured, self-propagating, and often fibrillar

211 We have identified a small, highly structured (shs)RNA that binds human recombinant

212 me of the more fascinating features of these highly structured single stranded RNAs (ssRNAs) with emp

213 e human delta hepatitis agent is a circular, highly structured single-stranded RNA lacking regular ru

214 s at one locus express surface proteins with highly structured size-variable repeating domains, where

215 xhibit distinct physiological signatures and highly structured spatial distributions with mediolatera

216 At both ages, twitches exhibited highly structured spatiotemporal properties at multiple

217 Highly structured specific psychotherapy was moderately

218 plexes consist of SRP proteins and a single, highly structured SRP RNA.

219 proteins fold via parallel channels through highly structured submillisecond intermediates before ac

220 When analyzed within the context of highly structured, surface-associated communities (biofi

221 Biofilms are highly structured, surface-associated communities.

222 Gln3 is concentrated in or associated with a highly structured system in the cytosol, one that is pos

223 These results show how the highly structured T stem-loop region in a pre-tRNA subst

224 The accelerating and highly structured temporal pattern of thalamocortical ne

225 data and is not well-suited for signals with highly structured time-frequency representations.

226 n proteins reveals a remarkably dynamic, but highly structured, tip growth apparatus.

227 How the ribosomal 30S subunit assembles on highly structured TIR is not known.

228 tify orientations of the apatite crystals in highly structured tissue matrices such as bone.

229 NC destabilizes the highly structured transactivation response region (TAR)

230 These findings disclose a highly structured transcriptional network that couples m

231 for most positions, indicating a polarized, highly structured TSE for folding of P. aeruginosa apo-a

232 vage sites within a large (4.2-kilobase) and highly structured viral mRNA, the 26 S subgenomic RNA of

233 on the interaction of the Rev protein with a highly structured viral RNA sequence, the Rev-responsive

234 he interleukin-2 promoter as well as certain highly structured viral RNAs.

235 he interaction of PKR with a number of other highly structured viral single-stranded RNAs, which inhi

236 R function can be evaded by transcription of highly structured virus-encoded dsRNA inhibitors that bi

237 MMN impairments were more likely to live in highly structured vs independent settings.

238 r cavities can be filled at equilibrium with highly structured water clusters.

239 These highly structured water molecules line up in a string th

240 er that the trapped intermediate ensemble is highly structured with little exposed hydrophobic surfac

241 solution studies suggest that the domain is highly structured, with the three stems assuming a Y-sha