ライフサイエンスコーパス: hilus

1 1/CA3 and polymorph cells within the dentate hilus).

2 of D cells, largely insulating them from the hilus.

3 r layer) and on interneuron dendrites in the hilus.

4 region and dentate inner molecular layer and hilus.

5 lls found in the highly vascularized ovarian hilus.

6 lar layer, but it was reduced in the dentate hilus.

7 entially in the suprapyramidal region of the hilus.

8 sity bilaterally in area CA1 and the dentate hilus.

9 nd parvalbumin-immunoreactive neurons in the hilus.

10 in hippocampal regions CA1, CA3 and dentate hilus.

11 ell and molecular layers, and in the dentate hilus.

12 e stratum pyramidale of CA3, and the dentate hilus.

13 ata alveus/oriens/pyramidale and the dentate hilus.

14 oth CA1 and CA3 subfields and in the dentate hilus.

15 the dentate molecular layer, and the dentate hilus.

16 ely in GABAergic interneurons of the dentate hilus.

17 labeled Thy 1-positive cells in the JGA and hilus.

18 s in the cornu Ammonis (CA) 1, CA2, CA3, and hilus.

19 he granule cell layer but ineffective in the hilus.

20 intrinsic excitatory input from the dentate hilus.

21 of the granule layer and mossy cells of the hilus.

22 rons in CA1-3 stratum oriens and the dentate hilus.

23 the inner molecular layer and throughout the hilus.

24 other conditions, newborn GCs appear in the hilus.

25 a parallel fiber retraction from the dentate hilus.

26 on EGCs, especially those restricted to the hilus.

27 s after paired electrical stimulation of the hilus.

28 ironment migrate aberrantly into the dentate hilus.

29 opriate target cells in the CA3 area and the hilus.

30 pyramidal-shaped morphology on entering the hilus.

31 rgo a compensatory sprouting response in the hilus.

32 ields CA1, CA3 and the dentate gyrus/dentate hilus.

33 ergic interneurons in the molecular layer or hilus.

34 appearance of ectopic granule neurons in the hilus.

35 onounced in R47H carriers (mean [SD], in the hilus: 0.114 [0.13] for R47H_AD vs 0.574 [0.26] for cont

36 Of the total neuron loss in the hilus, 97% is attributed to two cell types-mossy cells a

37 s were postsynaptic to axon terminals in the hilus, a site where mossy fiber collaterals are prevalen

38 of granule cells in the molecular layer and hilus, aberrant dendritic orientation, occurrence of bas

39 ed 20% acidophilic neurons in dorsal dentate hilus after 40-min SE and no difference between the 1-h

40 is that loss of mossy cells from the dentate hilus after seizures or traumatic brain injury directly

41 ithelium to establish a germinal zone in the hilus and a secondary germinal matrix, near the fimbria,

42 y in degenerating neurons in the hippocampal hilus and CA1, as well as in the cerebral cortex, thalam

43 pocampus, p-Erk and p-tau accumulated in the hilus and CA3 region of the dentate gyrus, where high le

44 ion of mGluR2/3 expression in mossy fiber at hilus and CA3 stratum lucidum in contrast with an enhanc

45 e characteristic of mossy fiber axons in the hilus and CA3.

46 ran exclusively in the stratum oriens of the hilus and CA3.

47 ministration had increased LENK-ir in the DG hilus and CA3c.

48 ed) granule neuron layer, concave toward the hilus and delimited by a hippocampal fissure; 2) nonperi

49 neuronal cell death in the CA1, CA2/3, CA3c, hilus and dentate gyrus were observed in the ipsilateral

50 anule cells that extended in the hippocampal hilus and eventually away into the alveus, and the fimbr

51 fiber pathway, in the stratum oriens of the hilus and field CA3.

52 The thin lamina between the hippocampal hilus and granule cell layer, or subgranule zone (SGZ),

53 sociated with damage in the CA1 and also the hilus and has a different neuropathological basis than H

54 the PV-positive interneurons of the dentate hilus and hippocampus, and the SS-positive cells of area

55 ls also appeared in ectopic locations in the hilus and inner molecular layer of the dentate gyrus.

56 n regions with known mitotic activity (e.g., hilus and lateral ventricle wall).

57 d that progenitors migrate aberrantly to the hilus and molecular layer after prolonged seizures and d

58 Ectopic putative DGCs also were found in the hilus and molecular layer of epileptic human dentate gyr

59 largement and ectopic neurons in the dentate hilus and molecular layer of the hippocampus.

60 ranule cells in ectopic locations within the hilus and molecular layer using both Golgi and retrograd

61 In the hilus and molecular layer, 4% of VAChT-ir terminals cont

62 rogenitor cell formations extending into the hilus and molecular layer, suggesting that seizures alte

63 -IR and DOR-IR, respectively) neurons in the hilus and MOR-IR neurons in the granule cell layer.

64 jacent to the granule cell layer, and 4) the hilus and mossy fiber projection to the CA3 pyramidal ce

65 clustering of GC currents in the interposed hilus and project them through the open side at a distan

66 c input to granule cells from neurons in the hilus and proximal CA3 field.

67 In addition, stimulation spots in the hilus and proximal CA3 pyramidal cell layer were more li

68 Within the hilus and proximal portions of the extrahilar CA3 field,

69 ilocarpine, Gal-IR fibers disappeared in the hilus and remained absent for up to 1 week afterward.

70 S expression declined in hippocampal CA3 and hilus and remained strongly expressed in hippocampal CA1

71 ells in the infrapyramidal blade crossed the hilus and sprouted into the supragranular layer of the s

72 el immunostaining in the mossy fibers at the hilus and stratum lucidum of the CA3 area.

73 has been shown that the interneurons of the hilus and stratum lucidum receive this dual monosynaptic

74 exhibits a rostral to caudal gradient in the hilus and the CA1 regions, (4) there are no sex differen

75 nitor cells divide at the border between the hilus and the granule cell layer (GCL).

76 tive neurons were counted in the hippocampal hilus and two levels of the cerebral cortex.

77 ntified in the hippocampal dentate gyrus and hilus and were related to behavioral performance.

78 ly in fine, varicose fibers primarily in the hilus and, to a lesser extent, in the granule cell and m

79 s, primarily in the cerebral cortex, dentate hilus, and amygdala.

80 pling zones covering the dentate gyrus, CA3c/hilus, and apical dendrites of field CA1, but not for th

81 cells expressing Mash1 reside in the dentate hilus, and by the third postnatal week they have largely

82 rus granule cell and molecular layers, CA2/3-hilus, and CA1), and across the rostral-caudal extent of

83 with inhibitory cells in the dentate gyrus, hilus, and CA3 regions as they integrate into hippocampa

84 liferation of granule cell precursors in the hilus, and defective axonal extension and misorientation

85 urons in the peritrauma cortex, hippocampus, hilus, and dentate gyrus.

86 s from dentate granule cells converge on the hilus, and excitatory hilar mossy cells redistribute the

87 cerebellar cortex, and hippocampus (CA1-CA3, hilus, and granule cell layer) but low in brainstem and,

88 bnormally positioned in the molecular layer, hilus, and granule cell layer.

89 activate neurons in the granule cell layer, hilus, and proximal CA3 pyramidal cell layer while measu

90 s per hippocampus in the granule cell layer, hilus, and pyramidal cell layer of CA3, CA2, and CA1 sub

91 mossy fiber pathway, particularly within the hilus, and regionally specific changes in synaptic prote

92 pression at presynaptic sites in the dentate hilus, and significant increases in postsynaptic density

93 rites were more likely to be confined to the hilus, and some exhibited dendritic features similar to

94 pment, formation of ectopic dendrites in the hilus, and the establishment of aberrant circuits.

95 pocampus, involving subregions CA1, CA3, the hilus, and the subiculum.

96 al terminals, e.g., olfactory glomeruli, CA3-hilus area, cerebellar molecular layer, and pars reticul

97 hilus, suggesting that dividing cells in the hilus belong to a distinct population, most likely glial

98 had lower levels of spinophilin mRNA in CA4 (hilus), CA3, the subiculum, and the entorhinal cortex th

99 elds were defined as the dentate fascia, the hilus (CA4), an amalgamation of the CA2 and CA3 subfield

100 In addition, in the dorsal dentate hilus (CA4), quantitative cell counts of normal and acid

101 arly postnatal mossy fibers severed near the hilus can regenerate across the lesion and elongate rapi

102 n of EG-VEGF was detected in the Leydig-like hilus cells found in the highly vascularized ovarian hil

103 In the central hilus (CH) of the dentate gyrus, Nav 1.1 immunoreactivit

104 They were also seen at the renal hilus close to the renal artery and along the interlobar

105 positive cells of the granule cell layer and hilus combined, and 33% of hilar calretinin-positive cel

106 -labeled small terminals and axons in the DG hilus compared to CA3 which may have contributed to regi

107 vels of LENK-immunoreactivity (ir) in the DG hilus compared to rats in diestrus or proestrus.

108 eased seizure-induced neuronal damage in the hilus compared with rats treated with beta-estradiol alo

109 BrdU) labeled cells in the dentate gyrus and hilus compared with the control groups when the animals

110 the central and infragranular regions of the hilus contained the highest densities of TrkA-immunoreac

111 r one-third of the molecular layer, with the hilus containing an average of only 26% of total axon le

112 CA2 stratum radiatum, CA3 stratum radiatum, hilus dentate gyrus and presubiculum, and in the cerebra

113 re observed in a few brain areas such as the hilus dentate in the hippocampus and some nuclei in the

114 n the ipsilateral CA1, CA2/3 and in the CA3c/hilus/dentate gyrus.

115 y of ictal discharges from the dentate gyrus/hilus (DGH) to the medial entorhinal cortex, instead of

116 Similar optical stimulation in the dentate hilus evoked no significant responses in granule cells o

117 ed very sparsely, whereas mossy cells in the hilus fired promiscuously in multiple locations and in m

118 lso eliminated by the removal of the dentate hilus from the slice.

119 dendrites extend into and ramify within the hilus, granule cell layer, and molecular layer of the de

120 The dentate hilus has been extensively studied in relation to its po

121 Examination of the hilus in adjacent Nissl-stained sections with the optica

122 aining neurons were found in the subgranular hilus in adult rats and were more widespread throughout

123 f NA nerves in splenic regions distal to the hilus in arthritic rats compared with nonarthritic rats.

124 e sparsely distributed along the edge of the hilus, in a different pattern from that of the densely p

125 n approximately equal proportions across the hilus, infragranular zone, and the inner, middle, and ou

126 integrity of a specific subpopulation in the hilus is coupled with age-related memory impairment.

127 However, a single episode of hilus lesion (HL)-induced limbic seizures stimulates a b

128 local circuit motifs we find enriched in the hilus may generate sparse neural representations involve

129 n the central and subgranular regions of the hilus, mossy cell axons established a low density of syn

130 naptic densities and microtubules of dentate hilus neurons and CA1 pyramidal cells.

131 e cells, CA1 and CA3 pyramidal cells than in hilus neurons.

132 midal cells in CA1 and subiculum compared to hilus neurons.

133 The hilus occupies a strategic position within the dentate g

134 interneuron progenitors into the hippocampal hilus of aged apoE4 knock-in mice without or with Abeta

135 In the hilus of animals that had recently undergone SE, some SO

136 er unit length than the axon segments in the hilus of both normal and kainate-treated rats but did no

137 vity was detected in the stratum lucidum and hilus of dentate gyrus in areas corresponding to the mos

138 dentified Orx(1)R as highly expressed in the hilus of DG, while Orx(2)R is abundant in CA(2).

139 Mossy fiber axons in the hilus of kainate-treated rats had more small terminal bo

140 spread throughout the granule cell layer and hilus of neonatal rats.

141 xon length compared with mossy fibers in the hilus of normal rats.

142 Mossy cells (MCs), a major cell type in the hilus of the dentate gyrus (DG), are unique in providing

143 hippocampal subregions [granule layer (GL), hilus of the dentate gyrus (DGH), cornu ammonis fields (

144 ial cell loss in the CA1 and CA3 fields, the hilus of the dentate gyrus (with sparing of granule cell

145 ic connectivity in local circuits within the hilus of the dentate gyrus and by increasing the diverge

146 n of the mossy fibers that includes both the hilus of the dentate gyrus and stratum lucidum of the CA

147 are located in greatest concentration in the hilus of the dentate gyrus and the stratum radiatum of t

148 ese dendrites branched and extended into the hilus of the dentate gyrus and were shown to be present

149 is also present in neurons localized to the hilus of the dentate gyrus at a site remote from the are

150 butyric acid (GABA)ergic neuron class in the hilus of the dentate gyrus consists of spiny somatostati

151 Mossy cells in the hilus of the dentate gyrus constitute a major excitatory

152 ABA) immunoreactivities were examined in the hilus of the dentate gyrus following removal of the chol

153 NPY-immunoreactive (IR) interneurons in the hilus of the dentate gyrus in animals with epilepsy (40-

154 deposition, a redistribution of Abeta to the hilus of the dentate gyrus in the hippocampus, and an al

155 ytin-filled granule cells projected from the hilus of the dentate gyrus into the supragranular layer

156 Loss of cells from the hilus of the dentate gyrus is a major histological hallm

157 We evaluated GABAergic interneurons in the hilus of the dentate gyrus of epileptic pilocarpine-trea

158 ) with ventral forebrain identities into the hilus of the dentate gyrus of mice with TLE and evaluate

159 anular ipsilateral layers, as well as in the hilus of the dentate gyrus of the hippocampal formation.

160 gG-saporin, NPY-immunolabeled neurons in the hilus of the dentate gyrus were examined by electron mic

161 amygdalostriatal zone and caudoputamen, the hilus of the dentate gyrus, and stratum lacunosum-molecu

162 nal somata in the mediodorsal neocortex, the hilus of the dentate gyrus, and the dorsolateral thalamu

163 ; in the olfactory tubercle; in CA1-CA3, the hilus of the dentate gyrus, and the subicular complex of

164 In the hilus of the dentate gyrus, LE-containing terminals (n =

165 In the hilus of the dentate gyrus, the study also supports the

166 tum oriens of hippocampal field CA1, and the hilus of the dentate gyrus.

167 ral lobe epilepsy display neuron loss in the hilus of the dentate gyrus.

168 jection of an NMDA receptor agonist into the hilus of the dentate gyrus.

169 persed interneurons, especially those in the hilus of the dentate gyrus.

170 ed interneurons in stratum oriens and in the hilus of the dentate gyrus.

171 me of aging were observed exclusively in the hilus of the dentate gyrus.

172 granule cells in the granule cell layer and hilus of the dentate gyrus.

173 s layer III of the entorhinal cortex and the hilus of the dentate gyrus.

174 rmed an early and selective cell loss in the hilus of the DG and area CA3 of hippocampus, ipsilateral

175 BrdU-labeled cells in the dentate gyrus and hilus of the hippocampus.

176 increase GAD cell counts in the hippocampal hilus of the injured brain.

177 ach, the first 8 cm of the duodenum, and the hilus of the liver were prepared as wholemounts and proc

178 spatial distribution of NG2(+) cells in the hilus of the mouse dentate gyrus, we demonstrate that NG

179 ehavioral correlates of cells located in the hilus of the rat dentate gyrus are unknown.

180 neurons containing either PARV or NPY in the hilus of the rat dentate gyrus were examined in single s

181 ed with newborn granule cells located in the hilus or granule cell layer or in wild-type controls.

182 s with multiple fields might be cells of the hilus or newborn granule cells.

183 l differentiation, granule cells born in the hilus or the subgranular zone begin to express NeuroD fo

184 educed in the CA2 and CA3 subregions, and in hilus/polymorphic layer of the dentate gyrus.

185 Galanin (0.05 nmol) injected into the hilus prevented the induction of SSSE, and 0.5 nmol of g

186 3 pyramidal neurons (subfield CA3c) into the hilus rather than an evolutionary change of the mossy fi

187 stratum radiatum and moleculare, and in the hilus region of the dentate gyrus, strongly expressed al

188 ly to the population of large neurons in the hilus region of the dentate gyrus.

189 ein and lipid metabolism particularly in the hilus region of the hippocampus within days of mechanica

190 MARCKS expression declined gradually in the hilus, remained elevated in hippocampal CA1, CA3, and gr

191 nucleus of the trapezoid body, its main and hilus subnuclei, contained predominantly glycine-immunor

192 reater in the granule cell layer than in the hilus, suggesting that dividing cells in the hilus belon

193 In contrast, SOMIs with axon in the hilus, termed hilar interneurons (HILs), provide perisom

194 of the suppressive effect was larger in the hilus than in the subgranular zone (SGZ).

195 cells are excitatory neurons in the dentate hilus that regulate dentate gyrus activity and function.

196 After detachment, the hilus, the opening through which postsynaptic processes

197 are born after seizures can migrate into the hilus, the results suggest that some newly born granule

198 ministration, Gal-IR neurons appeared in the hilus; these neurons increased in number after 1 d and g

199 otential recordings, which progress from the hilus to CA1 at 0.023 +/- 0.002 m/sec and in intracellul

200 unlike granule cells, which migrate from the hilus to the granular layer, interneurons traverse this

201 the seventh branching order (i.e., from the hilus toward the periphery of the liver), and probably b

202 d release of endogenous dynorphin within the hilus was effective in reducing hilar excitation of gran

203 As many types of neurons are found in the hilus, we used a new transgenic mouse expressing green f

204 eurons of the dentate granule cell layer and hilus were detected in numbers greater than previously r

205 atin-immunoreactive neuron number beyond the hilus were regionally selective and spared the CA1 field

206 er of the dentate granule cell layer and the hilus were studied in hippocampal slices using whole-cel

207 eled neurons, primarily in the infragranular hilus, were colocalized with neurons containing GABA imm

208 otic cells in the granule cell layer and the hilus, where granule cell precursors divide to generate

209 mmunoreactive (Gal-IR) fibers in the dentate hilus, whereas no Gal-IR neurons were observed.

210 eurons in the CA1 stratum oriens and dentate hilus (which themselves do not express COX-2), intensifi