ライフサイエンスコーパス: hint

1 the QuickSIN and the Hearing in Noise Test (HINT).

2 s rarity, contributes intriguing ontogenetic hints.

3 minus in governing the catalytic function of Hints.

4 r activity trends in 7/8 scaffolds for CoMFA+HINT (8/8 for CoMFA).

5 rent from a traditionally simplified concept hinting a molecular size increase-induced FA increase.

6 netic remodelling of surrounding genes, thus hinting a novel retrotransposition-independent role for

7 Based on our results, it gives us a hint about the evolution trajectory of HGT events.

8 gnitive aging and give science and society a hint about what would be possible if conditions were dif

9 sed to uncover functional modules and obtain hints about cellular organization.

10 of the new vinca derivatives, provide useful hints about how a given functionalization introduced at

11 ntal studies on the Pdu system have provided hints about its organization, a clear picture of how all

12 variant with bound 3-hydroxybenzoate provide hints about oxygen activation and substrate hydroxylatio

13 evolutionary paths between domains and give hints about protein evolution and the underlying biophys

14 limited and not sufficient to provide useful hints about secretion to the bloodstream.

15 ed analysis of PAG c-Fos expression provided hints about some of the physiological changes evoked by

16 l information makes it hard to interpret the hints about the insertion mechanism provided by biochemi

17 hese subsets is unknown but their immaturity hints against memory.

18 /IGHMBP2, CMT2T/HSJ1, CMTRID/COX6A1, ARAN-NM/HINT and GAN/GAN), for the genes related to autosomal re

19 The cellular function of Hint and the rationale for its evolutionary conservation

20 ure knowledge were subjected to CoMFA, CoMFA+HINT, and CoMSIA 3D-QSAR analyses.

21 Often, these "hints" are buried on expansive websites that require con

22 These studies, however, provide only hints as to the flexibility of each state.

23 membranes are bent in yeast and mammals give hints as to the molecular mechanisms we expect to see us

24 ion during development; more generally, they hint at a broader role for bistable switches in the init

25 l and retrotransposon transposition, and may hint at a common gap-repair mechanism in these diverse t

26 Furthermore, our data hint at a common pathway for DSB repair whereby BCR-ABL,

27 findings coupled with previous observations hint at a complex multifaceted role of the natural produ

28 These studies hint at a connection between ATP-binding site occupancy

29 al constitution of the retrieved DNA adducts hint at a direct link with an increase in NOCs and LPOs

30 tensive volcanism and high-temperature lavas hint at a global magma reservoir in Io, but no direct ev

31 t cats develop paw preferences by 1 year and hint at a relative stability in preferred paw use over t

32 ests could not reject neutrality, other data hint at a role for natural selection.

33 Yet previous studies hint at a surprisingly low diversity of intestinal IgA,

34 -dihydroxyphenylalanine) and lysine residues hint at a synergistic interplay in adhesion.

35 These findings hint at a top-down, cognitive enhancement of corticospin

36 functions in goal-directed movement but also hint at a wider variety of motor coordination roles.

37 flow is perhaps the most regimented of all, hint at an autonomous process of microfilament self-orga

38 These contacts hint at an even deeper density of encoded functions in v

39 Several studies hint at an important role for the C terminus of the alph

40 of IIS in diverse species, our results also hint at an intriguing connection of IIS and Ptf1a in mam

41 These observations hint at conserved roles for the NO(2)(-)-NO pool in cell

42 a major driver of species co-occurrence and hint at cooperative groups as recurring modules of micro

43 ribe a wide range of microbial responses and hint at evolutionary processes where a handful of succes

44 This could hint at higher speciation rates in more favourable low-e

45 Collectively, these results hint at intramolecular coevolution where the fold diverg

46 ent RNAs have distinct m(6)A patterns, which hint at mRNA fate.

47 The differences observed in genomic content hint at niche partitioning among the bifidobacterial spe

48 Our findings hint at possible design strategies for controlling elect

49 pectral and angular responses, these results hint at promising applications in solar-energy harvestin

50 nts-the Kuroshio and East Australia currents-hint at similar trends.

51 planta, these results nevertheless provide a hint at the currently unknown metabolic fate of this dit

52 ated with hormonal regulation of the Vdr and hint at the differential nature of VDR binding activity

53 These preliminary reactivity studies hint at the enormous potential synthetic utility of this

54 These findings hint at the existence of endogenous cytoplasmic ligands

55 Our results hint at the fate of "lost" plastic in the ocean, and pro

56 rigorous feature selection in LIBS and also hint at the feasibility of using a discrete filter based

57 Emerging data hint at the immune system's ability to intercept premali

58 These findings hint at the importance of elucidating how other glycans

59 idates salinosporamide A and bryostatin only hint at the incredible wealth of drug leads hidden just

60 nal changes observed near the 'Ca(2+) clasp' hint at the mechanism of Ca(2+)-dependent gating.

61 These observations hint at the polariton fluid dynamics in conditions of ex

62 iopolymers from other serpentinizing systems hint at the possibility of deep microbial life within th

63 at is interrelated with the metabolites, and hint at the underlying pathways.

64 en drawn to the unusual magnetic orders that hint at the underlying spin correlations.

65 Our results hint at the utility of this method to further model othe

66 ining tissue homeostasis in resting skin and hint at their contribution to signaling, cross-support,

67 perties as biological signal transducers and hint at their possible origins in evolution.

68 1), while recent studies on prokaryotic Agos hint at their role in the protection against invading DN

69 mpletely abolish the transcript response but hinted at a link with jasmonic acid and gibberellin sign

70 species richness and phenotypic traits that hinted at a potential adaptive radiation.

71 nt of valve-related and ischaemic events but hinted at a reduction in cardiovascular events in this h

72 Many studies have hinted at a role for p53 in meiosis, but how it function

73 Previous studies have hinted at a role for protein arginine methylation in imm

74 , which seemed to contradict this model, and hinted at an undiscovered active mechanism, as often fou

75 transmission to the possibility of HIV cure hinted at by the Mississippi baby experience, paediatric

76 nature of this modification has so far been hinted at indirectly.

77 Behavioral and neuroimaging studies have hinted at interrelations between processing of these thr

78 CRISPR spacer comparisons hinted at larger pools of accessory DNA sequences in Lp

79 tionalities of the identified MC9 substrates hinted at metacaspase functions other than those related

80 haeological and paleoenvironmental data have hinted at pre-Holocene rainforest foraging, earlier huma

81 nce that the human body harbors a microbiota hinted at the complexity of host-associated microbial ec

82 n intensively studied, genetic analyses long hinted at the existence of components that remained elus

83 Recent work has hinted at the linkage disequilibrium (LD)-dependent arch

84 erivatives obtained by semisynthesis (9a-11) hinted at the location of the biaryl axis and the presen

85 l microwear and stable isotope analyses have hinted at unexpected diversity and complexity in early h

86 cereals and perhaps other monocots has been hinted at, but remain unclear.

87 uired during cytokinesis in mammalian cells, hinting at a link between these pathways.

88 ils of these channels exhibit high homology, hinting at a long-shared and purposeful module.

89 /ATR is either unknown or poorly understood, hinting at a much broader and overarching role for these

90 ed attenuated pupillary responses to action, hinting at a noradrenergic contribution to impaired acti

91 lar loop induced water permeability of AqpB, hinting at a novel gating mechanism.

92 of the organization seen in higher mammals, hinting at a possible common origin.

93 eficient mutation A30P disrupted clustering, hinting at a possible loss of function phenotype for thi

94 tep in the infectious pathway nuclear entry, hinting at a possible perturbation of VP1 phospholipase

95 r interaction with the human sweet receptor, hinting at a previously unpredicted role of plasticity i

96 SAP30 SID complex can bind to nucleic acids, hinting at a role for a nucleolar localization sequence

97 data has offered novel quantitative insights hinting at a strong geographical confinement of human in

98 and the inhibition of pyoverdine production, hinting at a unique pathogenic-specific mechanism of act

99 ffer in only five nucleotides out of 15,452, hinting at a very low genetic diversity shortly before e

100 e functions for both the E5 and E6 proteins, hinting at additional targets and roles for these oncopr

101 of curvature, rather than curvature itself, hinting at an adaptation mechanism controlling the flage

102 In such hosts virulent strains can encyst, hinting at an explanation for the evolution of virulence

103 elect chloroplast envelope membrane proteins hinting at an origin of LDs, at least in part, from chlo

104 tream triterpene saponin biosynthetic genes, hinting at distinct functionalities within the regulatio

105 prediabetic stage to a somewhat lower level, hinting at functional reorganization of the cerebral net

106 atterns of inequality in nature and society, hinting at fundamental unifying mechanisms.

107 been implicated as the primary contributor, hinting at its future vulnerability.

108 ly and simultaneously enhanced MC mediators, hinting at MCs as direct targets.

109 xpression patterns within the mantle tissue, hinting at modular organisation, which is also observed

110 romoter ON/OFF times can be non-exponential, hinting at more complex transcriptional regulatory archi

111 istic for the majority of group VII members, hinting at more specific/localized roles for some of the

112 ind in close proximity on the SLX4 scaffold, hinting at possible cooperation.

113 elements and enhancers transcribe lincRNAs, hinting at possible roles in long-range control.

114 h conserved upstream sequences and activity, hinting at potential regulatory roles.

115 wild-type CFTR and the major F508del mutant, hinting at potential therapeutic strategies.

116 Paleoproterozoic rise in atmospheric oxygen, hinting at previously unexplored texture and variability

117 ealed potential cracks in the standard model-hinting at the existence of new phenomena.

118 he first time, the amorphization process and hinting at the formation of the Li(15)Si(4) phase.

119 -cyclohexadiene over its 1,4-isomer, perhaps hinting at the potential for concerted 2 e(-) /2 H(+) tr

120 tecting mice from lethal infection dose, and hinting at the role of these transcriptional regulators

121 an onlookers embodied the virtual character, hinting at the tight link between early, automatic codin

122 nges in both cis- and trans-acting elements, hinting at widespread and frequent turnover of regulator

123 This mapping hints at a common language for disordered states that wi

124 formation in the two other FaeG variants and hints at a heterogeneous binding pocket among the FaeG s

125 Recent literature hints at a misunderstanding of the difference between ac

126 RNase T in the mark-up or digestion of crRNA hints at a novel mechanism for evading the host CRISPR s

127 which the two associate and it additionally hints at a plausible biological role for the Grp94/OS-9

128 Although the structure of OMTs hints at a possible role as conduits for exchange, evide

129 e mitotic cyclin CYCLINA2;1 (CYCA2;1), which hints at a role for cell divisions in regulating hyponas

130 The unique substrate profile of XylO hints at a role in the degradation of xylan-derived olig

131 fluenced signaling of ETA-WT and ETA-6PD and hints at an additional phosphorylation-independent regul

132 ontact with ordered protein domains; it also hints at an approach to the stabilization of lipid micro

133 LOAD's correlation with cognitive traits and hints at an autoimmune component for ALS.

134 in presumed symbiotic and parasitic bacteria hints at an intermediate step in the process of genome r

135 whereas the behavior of amorphous particles hints at an underlying commonality among recently propos

136 might consider a practical contribution, and hints at directions the field might take in the future.

137 ht partitioning of oligofructan biosynthesis hints at distinct functions of the various fructan types

138 More importantly, the CLASH model hints at latitudinal, equatorial, and hemispheric upgrad

139 ggests a broader role for these proteins and hints at new pathways to be discovered.

140 yote with a remarkably plastic genome, which hints at peculiar genome maintenance mechanisms.

141 aeolian-like features resembling wind tails hints at regolith mobilization and erosion processes.

142 nsible for the high melting temperature, and hints at residual structure or compactness of the denatu

143 This hints at sex- or estrus-dependent features of BLA functi

144 tion research has produced new evidence that hints at significant commonalities between the neural su

145 functional importance and provide the first hints at structural elements that have important functio

146 r understanding TEs and genome evolution and hints at the diversity we verge on discovering by expand

147 tail-binding proteins such as Cdc13 and Pot1 hints at the evolutionary advantage of having multiple G

148 This proximity hints at the importance of electron correlation effects

149 The better performance of LaScSi, however, hints at the importance of the high concentration (>1.6

150 e of MalF-P2 adopts a similar semiopen state hints at the origin of the futile ATP hydrolysis of MalF

151 Our anatomical analysis hints at the possibility that subgroups of Odd neurons c

152 halpy-driven, higher stability of the former hints at the possibility that the 2'-substituent, in add

153 ease-relevant neural circuits in action, and hints at the potential of optogenetics to open up entire

154 h the evolution of animal neural systems and hints at the preservation of a vitally important functio

155 Our study hints at the therapeutic potential of the selective acti

156 the current repertoire of viral enzymes only hints at their overall potential.

157 ructural model of C9, as present in the MAC, hints at their putative roles in pore formation or recep

158 Our work hints at unexplored physics in Hofstadter butterfly syst

159 In the case of TFs, the latter criterion hints at upstream cross-regulation.

160 Hinted by that mRNA architecture determined secondary st

161 Despite indirect hints, direct evidence of a martian origin came with the

162 int on a long era of study of this topic and hint directly and indirectly at new avenues for this lin

163 he lack of obvious mutualism between HEN and HINT domains, HEN domains are persistently found at one

164 ights into the mutualism between the HEN and HINT domains.

165 Hedgehog/INTein (HINT) domains catalyzing protein splicing and their nest

166 ilarity to eukaryote Hint1 [Escherichia coli Hint (echinT) is 48% identical with human Hint1], prokar

167 coccus vulcanius, revealing a novel modified HINT fold that might provide new insights into the mutua

168 These data hint for a possible role of diverse T-cells subsets in d

169 shortening of the donor lifetime as a clear hint for Forster resonance energy transfer (FRET).

170 This work has thus provided an intriguing hint for further investigation into how the competence s

171 ble-dome superconducting phase may provide a hint for pursuing the superconducting coupling-mechanism

172 avage by the enzymes can be interpreted as a hint for the existence of sequence specificity.

173 Finally, we postulated first functional hints for 235 hypothetical genes.

174 itrate spike due to the biomass destruction, hints for an extraterrestrial source of Pt.

175 These findings are remarkable hints for an opioidergic modulation of the interaction b

176 sulting statistical models provide the first hints for coregulation patterns involving primary metabo

177 f the present article was to provide helpful hints for creating figures in SAS/GRAPH that meet the re

178 ults reveal a complex signaling network that hints for the first time at the granular layer as a majo

179 The resulting models can provide key hints for uncovering the evolutionary trajectories of ca

180 al performance on the Hearing in Noise Test (HINT) for which musicians outperformed the nonmusician c

181 length N-terminal and C-terminal residues of Hint from the E. coli complex with GMP.

182 ation and infection in the 21st century: new hints from decoding resolution mediators and mechanisms.

183 Gram-positive bacteria, typically encode one Hint gene.

184 48% identical with human Hint1], prokaryote Hint has been reported in only a few studies.

185 The Pab PolII intein has a common HINT (hedgehog intein) fold but contains an extra beta-h

186 r, its catabolic pathway, despite intriguing hints in a few distinct organisms, has never been establ

187 hese preclinical studies provide provocative hints into the direction MSC therapeutics may take in th

188 ckage containing a simple tutorial and usage hints is available from http://www.bioconductor.org.

189 Histidine triad nucleotide binding protein (Hint) is considered as the ancestor of the histidine tri

190 y better performance on the QuickSIN and the HINT measures with the binaural broadband hearing instru

191 The CoMFA+HINT model (docked alignment) showed the best statistics

192 r, vertebrate circadian receptors display no hint of a microvillar specialization and show an extreme

193 cating previous reports, 3-year-olds show no hint of anthropocentrism.

194 r System reveal it to be asteroidal, with no hint of cometary activity despite an approach within 0.2

195 g out of a huge number of analyses to find a hint of importance for a particular marker.

196 One hint of theta's function came from the discovery in rode

197 The first hints of a global public health crisis emerged with the

198 However, there are hints of a much more rapid communication network that ha

199 Some of these monolayers exhibit tantalizing hints of a poorly understood structural metal-to-insulat

200 tates at filling factors nu = 2p + 2/3, with hints of additional states appearing at nu = 2p + 3/5, w

201 There are hints of as yet unidentified sources of SL, as well as u

202 the accelerating pace of research and early hints of clinical successes to come were palpable throug

203 We also observed hints of disruptions in protein and small molecule traff

204 oped surveillance and response strategies to hints of microbial intent.

205 derstanding of gene regulation and providing hints of new phenomena.

206 ce of three VP4 molecules in one spike, only hints of the third molecule are observed above the capsi

207 Studies on present day MAPKs and MKKs hint on the way protein kinase networks may evolve.

208 opment of G4-specific antibodies and ligands hinted on their presence in vivo, but recent advances in

209 understanding of these processes can provide hints on delivering more efficient dental therapies in t

210 rial's processing history and hence provides hints on its place and date of production and on the int

211 l heterogeneity of TFII-I proteins, provides hints on search for regulatory pathways governing their

212 nsplantation (HSCT), thereby providing novel hints on the contribution of this subset to posttranspla

213 n a key phase of their life cycle, providing hints on the evolution and putative function of their ge

214 c insights into a new candidate phylum offer hints on the targeted cultivation of the chemically most

215 extual and biomedical factors in response to hints or red flags and the proportion of visits that res

216 ith those published previously gives further hints regarding the enzymatic mechanism of HAP.

217 y exploiting the SAR of a pyrrole subset and HINT scoring, guided ensemble docking of all 59 compound

218 Our results hint that (18)F-clofarabine can be used safely in humans

219 Conclusion: Our results hint that (18)F-clofarabine can be used safely in humans

220 Inspired by nature's hint that a beta-turn loop within calpastatin forms a br

221 This study gives a clear hint that also micro-organisms in anaerobic habitats can

222 rance of dominant sex determining genes, and hint that drift-induced selection may be a common force

223 lts can be considered as generic and give no hint that electronic quantum coherence plays any biofunc

224 umber of seemingly modern propatagial traits hint that feathering was a significant factor in how bas

225 er, our results implicate MED15 in HNSCC and hint that MED15 overexpression is a clonal event during

226 These results hint that sex moderates the association between the rs20

227 Interestingly, current published data hint that some of these mechanisms may be non-random wit

228 These results hint that temporal envelope cues influence spatial heari

229 hogens that undergo biphasic development and hint that the PSGL-1-targeting adhesin(s) may be upregul

230 oss-modality integration of information, and hint that the strength of these interactions depends on

231 nt observations of supernova remnants (SNRs) hint that they accelerate cosmic rays to energies close

232 Recent evidence has increasingly hinted that microRNAs may be involved in canalizing gene

233 Stokes radii measured by SEC hinted that PCNA in complex with NEIL1 (+/-DNA) was no l

234 Previous work has hinted that prospective and retrospective coding modes e

235 A further 8% of trees hinted that the probability of speciation changes accord

236 But recent studies have hinted that the process may not be so simple.

237 Previously published data have hinted that the RD of CaN is intrinsically disordered.

238 Previous studies have hinted that TRIB3 could be also involved in megakaryocyt

239 e the other attenuates behavioral responses, hinting that both "prorelapse" and "antirelapse" pathway

240 ning highly acidic stretches of amino acids, hinting that electrostatic interactions may be a common

241 ion (HR) repair of DNA double-strand breaks, hinting that FANCD2 utilizes HR proteins to mediate repl

242 is involved in postsynaptic signaling, while hinting that its signaling role may differ in different

243 bulk solution concentration of the stannane, hinting that more than one alkyl can be transferred from

244 served using Npi-bonded Cu(II) 2 O2 species, hinting that Ntau-imidazole ligation, conserved in all c

245 SOD1 accumulation in mitochondria, initially hinting that SOD1 may inhibit respiration directly withi

246 has a protein-coding conservation signature, hinting that stop codon readthrough might be common in D

247 aced to the last eukaryotic common ancestor, hinting that the removal of damaged mitochondrial conten

248 ins, the complex was also found to bind FAD, hinting that these cofactors may be involved in sensing

249 Emerging evidence hints that CAC may also promote long-term adherence to a

250 of distinct NS3 helicase knockout mutations hints that certain conformations of this enzyme might be

251 There are some hints that cortical neurons may also degenerate without

252 Such unprecedented cognitive flexibility hints that entirely novel behaviors could emerge relativ

253 sis using DFT-calibrated Huckel calculations hints that Fe-Fe multiple bonding underlies these short

254 ration in determining reversibility; and (6) hints that hepatic stellate cells may contribute to hepa

255 crystalline state, although there were also hints that including crystal contacts in the calculation

256 This new evidence hints that interindividual differences in the microbiome

257 This work hints that membrane-induced cross-fibrillation of unrela

258 -4 channels, evidence from the present study hints that NA may share the same activation pathway as 2

259 Finally, the analysis provided hints that one additional group of RRs, the type-C RRs,

260 There are hints that other alpha(1) subunit cytoplasmic domains ma

261 This research hints that our capacity to synchronize to a beat, i.e.,

262 Finally, there are tantalizing hints that the CDC pore-forming mechanism is more sophis

263 spect, the literature often contains earlier hints that the original judgment was not correct.

264 The stochastic nature of these processes hints that the surface/atmospheric abundances of biosphe

265 plexity of very different biological systems hints that there is something more general to be discove

266 Our findings hint to an evolutionary conserved mechanism for sensing

267 Mechanisms underlying this reorganization hint to essential links between pain, especially its aff

268 MSH2 deficiency, providing a new mechanistic hint to previously recognized neurological disorders in

269 ere potential associations between them were hinted to the MAPK signaling pathway.

270 nels in excised inside-out membrane patches, hinting to a direct block of TRPC5 by clemizole.

271 ala is more responsive to evocative stimuli, hinting to less local inhibitory regulation of the amygd

272 pathogen, reports from other countries gave hints to a completely new aspect: a possible decrease in

273 al systems cannot be designed, this tutorial hints to a methodology based on database analysis princi

274 Our study hints to a novel mechanism that implicates PKCepsilon-IR

275 e correlation of IP with Barrett's esophagus hints to a partly common pathogenesis.

276 ished very early following tumor seeding and hints to a role of IL-1beta in promoting early colonizat

277 approaches continue to provide promising new hints to answer these questions.

278 ferent distal pocket architecture, providing hints to engineer peroxidases with a higher rate of H2O2

279 lated member of ADAMTS family, have provided hints to investigate the role of the amino acid residues

280 ribosomal RNA distribution inside the cells hints to spatially differential gene expression.

281 ctroscopy, structure, and reactivity provide hints to the potential role of primary amine ligation in

282 anscription of RAB20 and TXNIP These results hint toward a novel function of HIF-1alpha as a potentia

283 e nucleation complex during capsid assembly, hint toward its participation in key protein-protein int

284 other negatively charged drugs and may also hint toward more general mechanisms underlying the induc

285 As a hint toward the induction of redox signaling, we have ob

286 Although few studies hint toward the proinflammatory role of bronchoalveolar

287 ce as a probe for PSMA-targeted RGS and also hint toward the unexpected potential of (99m)Tc-PSMA-I&S

288 rvice cost, emissions, and with split fares, hinting toward a wide passenger acceptance of such a sha

289 among the most conserved UTRs in the genome, hinting toward posttranscriptional regulation.

290 calization we observed may provide important hints toward potential functions of PrP(C).

291 crostructural markers in providing important hints toward the mechanisms underpinning training-induce

292 he structural plasticity in Bcl-xL providing hints toward the probable molecular mechanism for Bcl-xL

293 ions have a core of filamentous actin, which hints toward transport of virus particles through the us

294 estimates of the fundamental physical limit, hinting towards active sensing strategies.

295 for co-variation between sampler and sensor, hinting towards an 'optimization' for efficient chemorec

296 carbon atoms in the melt at high pressures, hinting towards possible exsolution of carbon from silic

297 Further, our model provides hints towards understanding the molecular basis of the n

298 the aim of this paper is to review outcomes, hints, trends, and perspectives in orbital decompression

299 A truncated mutant of Int, hInt V371S(UGA), lacking the putative zinc finger could

300 The bioinformatic tools, Wellington and HINT, were used to infer transcription factor footprints