ライフサイエンスコーパス: hippocampal sclerosis

1 farcts, arteriolosclerosis, Lewy bodies, and hippocampal sclerosis).

2 tion profile of Watson Grade 1 samples (mild hippocampal sclerosis).

3 A-binding protein 43 (TDP-43) pathology, and hippocampal sclerosis.

4 t common operation performed for adults with hippocampal sclerosis.

5 l model of temporal lobe epilepsy that lacks hippocampal sclerosis.

6 of human mesial temporal lobe epilepsy with hippocampal sclerosis.

7 sease scores and Braak and Braak stage), and hippocampal sclerosis.

8 eterotopia is not invariably associated with hippocampal sclerosis.

9 ith mesial temporal lobe epilepsy (MTLE) and hippocampal sclerosis.

10 zures may all contribute to the evolution of hippocampal sclerosis.

11 ergoing surgery for refractory seizures with hippocampal sclerosis.

12 s observed in two cases with combined AD and hippocampal sclerosis.

13 ay contribute to the epileptogenic nature of hippocampal sclerosis.

14 ial temporal lobe epilepsy due to unilateral hippocampal sclerosis.

15 es of temporal lobe epilepsy with or without hippocampal sclerosis.

16 sease, including cerebrovascular disease and hippocampal sclerosis.

17 mon being mesial temporal lobe epilepsy with hippocampal sclerosis.

18 ease in all the groups except for those with hippocampal sclerosis.

19 ic spatial task, in patients with unilateral hippocampal sclerosis.

20 Ammon horn atrophy in patients with TLE and hippocampal sclerosis.

21 3 and alpha-synuclein pathologies as well as hippocampal sclerosis.

22 o seizures, who had pathologically confirmed hippocampal sclerosis.

23 al medial temporal lobe epilepsy (25/26 left hippocampal sclerosis, 16/20 right hippocampal sclerosis

24 s with unilateral temporal lobe epilepsy and hippocampal sclerosis (24 left) and 26 healthy control s

25 % CI 1.6 to 3.8 for normal MRI compared with hippocampal sclerosis), a history of secondarily general

26 a mouse model of temporal lobe epilepsy with hippocampal sclerosis, a closed-loop system and selectiv

27 laterally in humans after TBI and resembling hippocampal sclerosis, a hallmark of temporal-lobe epile

28 nd fusiform gyrus whereas patients with left hippocampal sclerosis activated only right posterior hip

29 ople with mesial temporal lobe epilepsy with hippocampal sclerosis and 3591 control subjects.

30 esial temporal lobe epilepsy associated with hippocampal sclerosis and 44 healthy controls.

31 ople with mesial temporal lobe epilepsy with hippocampal sclerosis and 7552 control subjects, with va

32 All three patients with asymmetrical hippocampal sclerosis and all nine patients with unilate

33 Hippocampal sclerosis and benign tumors were associated

34 al lobe epilepsy (TLE) is commonly caused by hippocampal sclerosis and is frequently resistant to dru

35 phase, Braak stage, cerebrovascular disease, hippocampal sclerosis and Pathological 43-kDa transactiv

36 oreactive deposits, alpha-synucleinopathies, hippocampal sclerosis and prion disease) based on a neur

37 e dentate gyrus translate to the severity of hippocampal sclerosis and seizure burden in chronic epil

38 disease pathology, cerebrovascular disease, hippocampal sclerosis and the altered expression of thre

39 one of the three patients with asymmetrical hippocampal sclerosis and three of the nine patients wit

40 white matter, as was cortical astrogliosis, hippocampal sclerosis, and status marmoratus of the basa

41 ampal volume was related to AD pathology and hippocampal sclerosis, and the effects of hippocampal sc

42 izures in mesial temporal lobe epilepsy with hippocampal sclerosis are typically drug-resistant, and

43 temporal lobe seizure onset, had ipsilateral hippocampal sclerosis as the only brain lesion, and unde

44 Age of death and clinical features of hippocampal sclerosis associated with ageing (with or wi

45 There was no association between cases with hippocampal sclerosis associated with ageing and apolipo

46 en our ability to discriminate patients with hippocampal sclerosis associated with ageing clinically,

47 y but low word list recall distinguished the hippocampal sclerosis associated with ageing group at in

48 a first step in clinical differentiation of hippocampal sclerosis associated with ageing versus pure

49 udinal cognitive profile of 43 patients with hippocampal sclerosis associated with ageing was compare

50 Much remains unknown about hippocampal sclerosis associated with ageing.

51 o hippocampal sclerosis in the aged brain as hippocampal sclerosis associated with ageing.

52 al and pathological features associated with hippocampal sclerosis associated with ageing.

53 h Braak stage and the presence of TDP-43 and hippocampal sclerosis associated with global cognitive f

54 Furthermore, in patients with confirmed hippocampal sclerosis at post-mortem examination, stereo

55 5/26 left hippocampal sclerosis, 16/20 right hippocampal sclerosis) before and after anterior tempora

56 ssociated with amyloid plaques, tangles, and hippocampal sclerosis but not neocortical Lewy bodies or

57 sonance images in about 15% of patients with hippocampal sclerosis, but most such patients are exclud

58 Four infants had bilateral hippocampal sclerosis by magnetic resonance scans, inclu

59 Compared with the autopsies, hippocampal sclerosis cases with decreased neuron densit

60 from 27 patients subsequently proved to have hippocampal sclerosis demonstrated extrahippocampal stru

61 Hippocampal sclerosis describes a pattern of neuronal lo

62 pocampus, whereas patients with preoperative hippocampal sclerosis did not exhibit significant declin

63 mporal reorganization in patients with right hippocampal sclerosis during face encoding were not asso

64 eorganization observed in patients with left hippocampal sclerosis during word encoding and bilateral

65 ents with refractory partial epilepsy due to hippocampal sclerosis fail to become seizure free after

66 12 patients with unilateral MTLE and hippocampal sclerosis (five left and seven right MTLE) a

67 The most common categories were hippocampal sclerosis, found in 36.4% of the patients (8

68 ere reduced, whereas Braak stage, TDP-43 and hippocampal sclerosis frequency increased.

69 Mice stimulated for 24 hours developed hippocampal sclerosis, granule cell mossy fiber sproutin

70 tmortem findings on 1 patient suggested that hippocampal sclerosis had developed following the clinic

71 actory temporal lobe epilepsy and unilateral hippocampal sclerosis had repeat volumetric magnetic res

72 actory temporal lobe epilepsy and unilateral hippocampal sclerosis have progressive hippocampal atrop

73 inated inclusions (FTLD-U) in the setting of hippocampal sclerosis (HpScl) and Alzheimer's disease (A

74 n a better clinicopathological definition of hippocampal sclerosis (HS) and end folium sclerosis (EFS

75 er febrile status epilepticus (FSE) produces hippocampal sclerosis (HS) and temporal lobe epilepsy (T

76 One patient with pre-existing hippocampal sclerosis (HS) did not develop progressive h

77 stingly, this risk is lower in patients with hippocampal sclerosis (HS) relative to those without HS

78 ral lobe epilepsy (TLE) patients show marked hippocampal sclerosis (HS) upon pathological examination

79 ed to determine, in patients with or without hippocampal sclerosis (HS), if there was a correlation b

80 different subtypes of FTLD-TDP as well as in hippocampal sclerosis (HS), which represents a non-FTLD

81 tients with temporal lobe epilepsy (TLE) and hippocampal sclerosis (HS).

82 al lobe epilepsy (mTLE) caused by unilateral hippocampal sclerosis (HS).

83 unilateral temporal lobe epilepsy (TLE) with hippocampal sclerosis (HS-TLE, n = 26) was studied as an

84 focal cortical dysplasia (FCD; 14 cases) and hippocampal sclerosis (HS; eight cases).

85 Hippocampal sclerosis (HS; n = 16), non-HS (n = 10), and

86 ry in hippocampi from three groups: TLE with hippocampal sclerosis (HS; n = 17), epileptic hippocampi

87 Hippocampal sclerosis, identified in 40% (bilateral in 4

88 oinfarcts, cystic infarcts, Lewy bodies, and hippocampal sclerosis in all studies.

89 l attempts to replicate the human pattern of hippocampal sclerosis in animals indicate that prolonged

90 Similar to human patients, hippocampal sclerosis in sea lions was unilateral in 79%

91 different underlying causes, and we refer to hippocampal sclerosis in the aged brain as hippocampal s

92 nt in temporal lobe epilepsy with or without hippocampal sclerosis, in addition to a common methylati

93 he three patients with bilateral symmetrical hippocampal sclerosis, in one of the three asymmetrical

94 Hippocampal sclerosis is a relatively common neuropathol

95 tant, and mesial temporal lobe epilepsy with hippocampal sclerosis is frequently associated with impo

96 These results indicate that classic hippocampal sclerosis is uniquely produced by a single e

97 cause of mesial temporal lobe epilepsy with hippocampal sclerosis is unknown, but there is an associ

98 ly common, and not typically associated with hippocampal sclerosis, is an appropriate target for cont

99 Neurofibrillary tangles (NFTs), hippocampal sclerosis, lacunar infarcts, hyaline atheros

100 Hippocampal sclerosis may be reliably identified, quanti

101 sial temporal lobe epilepsy with and without hippocampal sclerosis (mTLE + HS and mTLE -HS) to invest

102 ries with mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS) and to elucidate the cli

103 ubset of cases with neuropathology-confirmed hippocampal sclerosis (n=106).

104 osis positive patients compared with 9.7% of hippocampal sclerosis negative patients.

105 ern of selective neuron loss called "classic hippocampal sclerosis." No single experimental injury ha

106 a subsample of frontal cortex sections from hippocampal sclerosis of ageing (n = 15) and control (n

107 yses incorporate 226 cases of autopsy-proven hippocampal sclerosis of ageing and 1792 controls.

108 Arteriolosclerosis appears specific to hippocampal sclerosis of ageing brains, because brains w

109 Hippocampal sclerosis of ageing is a prevalent brain dis

110 rodmann area 9) was strongly associated with hippocampal sclerosis of ageing pathology (P < 0.001).

111 ntre) showing a specific association between hippocampal sclerosis of ageing pathology and arteriolos

112 We found no evidence of associations between hippocampal sclerosis of ageing pathology and lacunar in

113 Individuals with hippocampal sclerosis of ageing pathology did not show i

114 e correlation between arteriolosclerosis and hippocampal sclerosis of ageing pathology was strong in

115 dimensions that were unchanged in cases with hippocampal sclerosis of ageing versus controls.

116 In frontal cortex of cases with hippocampal sclerosis of ageing, smooth muscle actin-imm

117 acts multiple brain areas and contributes to hippocampal sclerosis of ageing.

118 erosis and all nine patients with unilateral hippocampal sclerosis on MRI showed unilateral reduction

119 mesial temporal lobe epilepsy and unilateral hippocampal sclerosis on MRI than was subsequently histo

120 to have unilateral or bilateral asymmetrical hippocampal sclerosis on MRI.

121 No evidence of hippocampal sclerosis or dysplasia was present on brain

122 c resonance imaging (MRI) or MRI evidence of hippocampal sclerosis over a 10-year period.

123 out "high"-level ADNC, Lewy body disease, or hippocampal sclerosis pathologies; this group was enrich

124 ears correlated with increased prevalence of hippocampal sclerosis pathology and decreased prevalence

125 Hippocampal sclerosis pathology can be associated with d

126 t the disease is usually bilateral even when hippocampal sclerosis pathology is not obvious by haemat

127 Hippocampi from hippocampal sclerosis patients (n = 28) and temporal mas

128 sclerosis, in one of the three asymmetrical hippocampal sclerosis patients and in six of the nine un

129 for changes in neuron densities showed that hippocampal sclerosis patients had increased AMPA and NM

130 s patients and in six of the nine unilateral hippocampal sclerosis patients.

131 43 immunohistochemistry was seen in 89.9% of hippocampal sclerosis positive patients compared with 9.

132 w international consensus classification for hippocampal sclerosis proposed by the International Leag

133 quent memory in patients with left and right hippocampal sclerosis, respectively, representing effect

134 osed the alternative hypothesis that classic hippocampal sclerosis results from a single excitatory e

135 Patients with right hippocampal sclerosis showed increased temporal activati

136 left hippocampus whereas patients with left hippocampal sclerosis showed significant additional righ

137 ll three patients with bilateral symmetrical hippocampal sclerosis showed significant bilateral reduc

138 d three of the nine patients with unilateral hippocampal sclerosis showed significant reductions of F

139 Patients with right hippocampal sclerosis showed subsequent visual memory ef

140 hese findings suggest that tangle pathology, hippocampal sclerosis, TDP-43 and perforant pathway syna

141 ontrolling for amyloid plaques, tangles, and hippocampal sclerosis, TDP-43 pathology was associated w

142 ymmetry was more pronounced in patients with hippocampal sclerosis than in those without.

143 mmonic and perforant pathways that accompany hippocampal sclerosis, the pathological hallmark of this

144 on with outcome for epilepsy associated with hippocampal sclerosis, this figure is low.

145 er symmetrical on MRI (bilateral symmetrical hippocampal sclerosis; three patients) or bilateral but

146 or bilateral but asymmetrical (asymmetrical hippocampal sclerosis; three patients), and in nine pati

147 est series of autopsy-verified patients with hippocampal sclerosis to date, we characterized the clin

148 with associated another principal lesion as hippocampal sclerosis, tumor, vascular malformation or a

149 atients with intractable mTLE and unilateral hippocampal sclerosis underwent comprehensive presurgica

150 re freedom and histopathological evidence of hippocampal sclerosis was not found.

151 -grade tumor were the most common causes and hippocampal sclerosis was rare.

152 In addition, hippocampal sclerosis was specific to participants with

153 -resistant focal epilepsy requiring surgery, hippocampal sclerosis was the most common histopathologi

154 Gross and microscopic cerebral infarcts and hippocampal sclerosis were also identified.

155 infarcts, Lewy bodies, TDP-43 pathology, and hippocampal sclerosis were associated with progressive c

156 nd hippocampal sclerosis, and the effects of hippocampal sclerosis were greater for subjects with low

157 ed Wada result or the presence of unilateral hippocampal sclerosis, whereas none of the patients with

158 on of inflammatory processes associated with hippocampal sclerosis which warrants further studies elu

159 nd a quantitative MRI diagnosis of bilateral hippocampal sclerosis, which appeared either symmetrical

160 equency epileptic seizures cause progressive hippocampal sclerosis, which is associated with caspase-

161 ases with substantial lesions in the form of hippocampal sclerosis, which suggests that neuronal loss

162 eport 10 right-handed TLE patients with left hippocampal sclerosis who underwent left hippocampal res

163 pileptic patients (11 women) with unilateral hippocampal sclerosis, who served as a hippocampal lesio

164 ases with mesial temporal lobe epilepsy with hippocampal sclerosis with (overall n = 757) and without

165 onal analysis showed that patients with left hippocampal sclerosis with better verbal memory addition

166 nal analysis showed that patients with right hippocampal sclerosis with better visual memory activate

167 ation for mesial temporal lobe epilepsy with hippocampal sclerosis with febrile seizures at the sodiu

168 anding of mesial temporal lobe epilepsy with hippocampal sclerosis with febrile seizures, and open av

169 dant neocortical amyloid-beta deposition and hippocampal sclerosis with its attendant TDP-43 patholog

170 cBZR in mesial temporal lobe epilepsy due to hippocampal sclerosis with optimal sensitivity.

171 tensive neuronal injury that defines classic hippocampal sclerosis, without giving any clinical indic