ライフサイエンスコーパス: hippocampal-dependent

1 performed TP and control tasks that are not hippocampal dependent.

2 In primates relatively few hippocampal-dependent abilities (e.g. some aspects of re

3 Interestingly, the hippocampal-dependent alterations were not present in ju

4 In the present study, we examined hippocampal-dependent and -independent working memory us

5 affect fear conditioning, a memory task with hippocampal-dependent and hippocampal-independent compon

6 eptors for the acquisition and expression of hippocampal-dependent and hippocampal-independent forms

7 cognitive assessments distinguishing between hippocampal-dependent and hippocampal-independent functi

8 ome circumstances, delay conditioning can be hippocampal-dependent and trace conditioning can be spar

9 Therefore, the effects of stress on working (hippocampal-dependent) and reference (hippocampal-indepe

10 ction in young or middle-aged animals in the hippocampal-dependent appetitive radial maze task.

11 critical regulator of synaptic function and hippocampal-dependent associative and spatial learning.

12 The results suggest a relationship between hippocampal-dependent behavior and experience-dependent

13 AP5 impaired measures of hippocampal-dependent behavior and increased locomotor a

14 es of synaptic strength were correlated with hippocampal-dependent behavior and synaptic plasticity f

15 rve injury (SNI) neuropathic pain in mice on hippocampal-dependent behavior and underlying cellular a

16 es adult hippocampal neurogenesis and alters hippocampal-dependent behavior in rodents.

17 Evaluation of hippocampal-dependent behavior revealed parallel finding

18 straint stress enhanced freezing to context (hippocampal-dependent behavior) and tone (hippocampal-in

19 LTP and LTD coincides with the emergence of hippocampal-dependent behavior, implying that Ras-GRF pr

20 ne and synapse densities, and impairments in hippocampal-dependent behavior.

21 campal lateralization may play a role in the hippocampal-dependent behavioral deficit.

22 accumulation, tau hyperphosphorylation, and hippocampal-dependent behavioral impairments.

23 compared to sham-irradiated controls in the hippocampal-dependent behavioral task.

24 ed neuronal morphogenesis may be involved in hippocampal-dependent behaviors.

25 ult hippocampal neuron shape acquisition and hippocampal-dependent behaviors.

26 Behaviourally, Fmr1 KO rats show deficits in hippocampal-dependent, but not hippocampal-independent,

27 , the specific role of the D1R versus D5R in hippocampal dependent CFC has not been investigated.

28 tablish SUMO as a novel regulator of LTP and hippocampal-dependent cognition and additionally implica

29 ic factor (BDNF), a growth factor central to hippocampal-dependent cognition and plasticity, instead

30 ration and increases synaptic plasticity and hippocampal-dependent cognition in aged mice.

31 y neurotransmitters, have been implicated in hippocampal-dependent cognition.

32 Hippocampal-dependent cognitive behavior, neurogenesis,

33 As a tool for studying the mechanisms of hippocampal-dependent cognitive decline, we developed a

34 -molecule inhibitor of the ISR, reversed the hippocampal-dependent cognitive deficits induced by TBI

35 n that chronic psychological stress produces hippocampal-dependent cognitive deficits that are consis

36 agonism resulted in a sparing of TBI-induced hippocampal-dependent cognitive dysfunction and reduced

37 potential explanation for the maintenance of hippocampal-dependent cognitive function after androgen

38 ally, or locally in the hippocampus, impairs hippocampal-dependent cognitive function and neurogenesi

39 , both M(1) agonists enhanced acquisition of hippocampal-dependent cognitive function but did not rev

40 amyloid-beta (Abeta) protein expression, and hippocampal-dependent cognitive function in an animal mo

41 hippocampal CA1 neurons and preservation of hippocampal-dependent cognitive function when examined a

42 uble-edged sword': mild stress might promote hippocampal-dependent cognitive function, whereas severe

43 (LTP) in hippocampal CA1 pyramidal cells and hippocampal-dependent cognitive function.

44 Circulating estrogen levels and hippocampal-dependent cognitive functions decline with a

45 ycle in female rats correlate with increased hippocampal-dependent cognitive performance in a manner

46 antation exhibited superior performance on a hippocampal-dependent cognitive task 4 months postirradi

47 expression, concomitant with impairments on hippocampal-dependent cognitive tasks, were observed in

48 d mice exhibited significant improvements in hippocampal-dependent contextual fear conditioning compa

49 emonstrated that memory consolidation of the hippocampal-dependent contextual fear-conditioning task

50 e glucose group showed superior retention of hippocampal-dependent contextual learning at test relati

51 ng glucose consumption improves retention of hippocampal-dependent contextual learning but not cued l

52 rimentally examined the effect of glucose on hippocampal-dependent contextual learning versus cued fe

53 k2(-/-) mice exhibited a striking deficit in hippocampal-dependent (contextual) and hippocampal-indep

54 Impaired, hippocampal-dependent, contextual fear conditioning (CFC

55 ations may lead to therapeutic approaches to hippocampal-dependent dysfunctions, such as Alzheimer's

56 ness, faster conduction speeds, and enhanced hippocampal-dependent emotional learning.

57 episode after incidental encoding based upon hippocampal-dependent episodic memory.

58 drome (DS) patients exhibit abnormalities of hippocampal-dependent explicit memory, a feature that is

59 conditional knock-out mice exhibit impaired hippocampal-dependent fear learning.

60 rat postnatal day (P) 7 permanently impairs hippocampal-dependent function in mature (P60) rats beca

61 ssed animals were impaired in retention of a hippocampal-dependent hidden platform version of the Mor

62 beta (ERbeta) in mediating performance on a hippocampal-dependent, hormone-sensitive task, inhibitor

63 ptor protein tyrosine phosphatase Shp2, show hippocampal-dependent impairments in spatial learning an

64 These data indicate that hippocampal-dependent impairments in spatial processing

65 us work shows that sleep deprivation impairs hippocampal-dependent learning and long-term potentiatio

66 road forebrain regions of adult mice impairs hippocampal-dependent learning and long-term potentiatio

67 inase II (CAMKII) are critical modulators of hippocampal-dependent learning and LTP.

68 arly gene that has been widely implicated in hippocampal-dependent learning and memory and is believe

69 of Hdac4 in brain results in impairments in hippocampal-dependent learning and memory and long-term

70 the hippocampus of middle-aged mice enhances hippocampal-dependent learning and memory and restores i

71 Hippocampal-dependent learning and memory deficits have

72 ing conditional knock-out mice, we show that hippocampal-dependent learning and memory deficits in CD

73 ory synapse number, synaptic plasticity, and hippocampal-dependent learning and memory due to a failu

74 rch and theory point to the possibility that hippocampal-dependent learning and memory mechanisms tra

75 pal neurochemistry, neuronal morphology, and hippocampal-dependent learning and memory processes.

76 Exercise improves performance on hippocampal-dependent learning and memory tasks and incr

77 A1 synapses, and have no deficits in several hippocampal-dependent learning and memory tasks.

78 5-HT(1A)-KO animals showed a deficit in hippocampal-dependent learning and memory tests, such as

79 e experimental design was that the status of hippocampal-dependent learning and memory was documented

80 By contrast, hippocampal-dependent learning and memory were not affec

81 units/kg diet, respectively) vitamin D3, and hippocampal-dependent learning and memory were then test

82 Kcnj6 triploid mice exhibit deficits in hippocampal-dependent learning and memory, altered respo

83 Indeed, leptin influences hippocampal-dependent learning and memory, and more rece

84 and suggest that the Syt IV mutation affects hippocampal-dependent learning and memory, as well as mo

85 tion of HCN1 from forebrain neurons enhances hippocampal-dependent learning and memory, augments the

86 ved in several forms of plasticity including hippocampal-dependent learning and memory, experience-de

87 rs hippocampus-related functions, we studied hippocampal-dependent learning and memory, synaptic plas

88 rtant for the synaptic plasticity underlying hippocampal-dependent learning and memory.

89 vival in the hippocampus as well as enhanced hippocampal-dependent learning and memory.

90 f D(1)/D(5) receptors is required for normal hippocampal-dependent learning and memory.

91 nscription factor in the CNS of mice impairs hippocampal-dependent learning and memory.

92 ion from the locus ceruleus are required for hippocampal-dependent learning and memory.

93 f synaptic connectivity and thus facilitates hippocampal-dependent learning and memory.

94 in vivo are associated with improvements in hippocampal-dependent learning and memory.

95 ity and have been implicated as mediators of hippocampal-dependent learning and memory.

96 y, sensorimotor retardation, and deficits in hippocampal-dependent learning and memory.

97 med feeding resulted in dramatic deficits in hippocampal-dependent learning and memory.

98 9, rescued Abeta-induced deficits in LTP and hippocampal-dependent learning and memory.

99 al suppressor of CA2 synaptic plasticity and hippocampal-dependent learning and memory.

100 an increasingly important role in supporting hippocampal-dependent learning and the modulation of moo

101 ke patterns and sleep EEGs and showed normal hippocampal-dependent learning as assayed by the Morris

102 ent causes hyperactivity and more pronounced hippocampal-dependent learning deficits.

103 eration in the cortex and hippocampus and in hippocampal-dependent learning has been demonstrated, it

104 nesis, with implications for amelioration of hippocampal-dependent learning impairments associated wi

105 We demonstrate that exercise enables hippocampal-dependent learning in conditions that are no

106 potential therapeutic strategy for improving hippocampal-dependent learning in patients with mesial t

107 In experiments with rats, we found that the hippocampal-dependent learning of new paired associates

108 creased after trace eyeblink conditioning, a hippocampal-dependent learning paradigm.

109 ative evidence of behavioral disruption in a hippocampal-dependent learning task following developmen

110 e exposed to the stressor and trained on the hippocampal-dependent learning task of trace conditionin

111 Rats were trained as adults on the hippocampal-dependent learning task of trace eyeblink co

112 ve function in arrhythmic animals by using a hippocampal-dependent learning task.

113 al forms of hippocampal LTP and a particular hippocampal-dependent learning task.

114 long-term potentiation (LTP), and results in hippocampal-dependent learning that seems more rigid and

115 neurotransmitter serotonin (5-HT) modulates hippocampal-dependent learning through serotonin 1A (5-H

116 ear extinction (e.g., appetitive extinction, hippocampal-dependent learning).

117 ormal response to context, indicating intact hippocampal-dependent learning, but reduced response to

118 Hippocampal-dependent learning, memory and ischemic neur

119 ejuvenates hippocampal function and improves hippocampal-dependent learning.

120 fear conditioning, an indicator of defective hippocampal-dependent learning.

121 creases in neuronal activity associated with hippocampal-dependent learning.

122 hippocampus and consequently to deficits in hippocampal-dependent learning.

123 ication necessary for Hebbian plasticity and hippocampal-dependent learning.

124 asticity at Schaffer collateral synapses and hippocampal-dependent learning.

125 re, we focus primarily on genetic studies of hippocampal-dependent learning.

126 Acetylcholine critically influences hippocampal-dependent learning.

127 hanges are responsible for the impairment in hippocampal-dependent learning.

128 ion impairs long-term potentiation (LTP) and hippocampal-dependent learning.

129 were consistent across tasks, regardless of hippocampal-dependent learning.

130 tic potentiation in hippocampus and regulate hippocampal-dependent learning.

131 on making that cannot be explained easily by hippocampal-dependent long-term memory or spatial cognit

132 that are critical for their contribution to hippocampal-dependent long-term memory.

133 of this inhibition lowers the threshold for hippocampal-dependent long-term synaptic potentiation an

134 cted question after incidental encoding in a hippocampal-dependent manner, consistent with the use of

135 rative process supporting the integration of hippocampal-dependent memories into neocortical networks

136 We hypothesize that the consolidation of hippocampal-dependent memories might not depend on SWS p

137 to involve the gradual transfer of transient hippocampal-dependent memories to distributed neocortica

138 r regulating gene expression associated with hippocampal-dependent memories.

139 cts in some forms of synaptic plasticity and hippocampal-dependent memories.

140 odulate both the encoding and the storage of hippocampal-dependent memories.

141 participate in the formation and storage of hippocampal-dependent memories.

142 when" memory while preserving other forms of hippocampal-dependent memories.

143 Finally, LBP k.o. mice show impaired hippocampal-dependent memory and increased anxiety-like

144 Dopamine (DA) is required for hippocampal-dependent memory and long-term potentiation

145 r-deficient mice and found that they develop hippocampal-dependent memory and synaptic dysfunction, w

146 the hippocampus and is reflected in enhanced hippocampal-dependent memory and synaptic plasticity.

147 1 reduces GluA1 and GluA2 levels and impairs hippocampal-dependent memory and synaptic plasticity.

148 That osteocalcin (OCN) is necessary for hippocampal-dependent memory and to prevent anxiety-like

149 DH E2 infusion enhances hippocampal-dependent memory by rapidly activating extra

150 t CREB-mediated transcription is integral to hippocampal-dependent memory consolidation processes.

151 Since PAF is required for hippocampal-dependent memory consolidation, and since th

152 ation by low-dose anisomycin failed to block hippocampal-dependent memory consolidation.

153 vely support the idea that the transience of hippocampal-dependent memory directly reflects the turno

154 is underscored by behavioral impairments in hippocampal-dependent memory displayed by MMP-9 null-mut

155 However, the effect of dietary intake on hippocampal-dependent memory during childhood has remain

156 the role of apamin-sensitive SK channels on hippocampal-dependent memory encoding and retention was

157 ation of hippocampal synaptic plasticity and hippocampal-dependent memory encoding.

158 investigated the role of mRNA methylation in hippocampal-dependent memory formation in mice.

159 patients experience cognitive deficits, and hippocampal-dependent memory impairment has been reporte

160 The hippocampal-dependent memory impairment was paralleled b

161 (BDNF) modulates hippocampal plasticity and hippocampal-dependent memory in cell models and in anima

162 from forebrain glutamatergic neurons impairs hippocampal-dependent memory in male conditional knock-o

163 ults indicate that exogenous OCN can improve hippocampal-dependent memory in mice and identify molecu

164 pocampus, as transducing OCN's regulation of hippocampal-dependent memory in part through inositol 1,

165 th elevated anxiety and impaired working and hippocampal-dependent memory in these mice.

166 The latter, hippocampal-dependent memory loss occurred in the absenc

167 synaptic learning rule for distinct forms of hippocampal-dependent memory mediated by distinct hippoc

168 and spatial recognition tasks are solved by hippocampal-dependent memory processes.

169 ion, and long-term plasticity, important for hippocampal-dependent memory processes.

170 ation facilitates hippocampal plasticity and hippocampal-dependent memory storage by modulating the a

171 sed that performing the 2-Back WM prior to a hippocampal-dependent memory task would impair performan

172 'matching-to-place' Morris water maze test-a hippocampal-dependent memory task-without the convulsant

173 no behavioral abnormalities were detected in hippocampal-dependent memory tasks, which correlated wit

174 role for neurogenesis in some, but not all, hippocampal-dependent memory tasks.

175 are not only affected by the formation of a hippocampal-dependent memory, but also participate in it

176 relevance of journey-dependent activity for hippocampal-dependent memory, however, is not well under

177 ove neurocognitive functioning, particularly hippocampal-dependent memory, in children with FASDs.

178 ed long term potentiation (LTP) and impaired hippocampal-dependent memory, suggesting a 'detrimental'

179 o investigate the roles phosphatases play in hippocampal-dependent memory, we studied transgenic mice

180 ss and may be associated with enhancement of hippocampal-dependent memory.

181 nduced cognitive impairments have focused on hippocampal-dependent memory.

182 by suggesting that stress should also impair hippocampal-dependent memory.

183 intervals commensurate with the duration of hippocampal-dependent memory.

184 echanism underlying the action of ghrelin on hippocampal-dependent memory.

185 ibit a spectrum of individual differences in hippocampal-dependent memory.

186 beta, regulated transcription and maintained hippocampal-dependent memory.

187 s an increase in sleep drive and deficits in hippocampal-dependent memory.

188 Feeding behavior is heavily influenced by hippocampal-dependent mnemonic functions, including epis

189 c acetylcholine receptors (mAChRs) influence hippocampal-dependent mnemonic processing.

190 rs consolidation of long-term memory, in the hippocampal-dependent Morris water maze spatial memory t

191 and contextual memory but were impaired in a hippocampal-dependent, nonmatching-to-place working memo

192 sgenic mice showed significant deficits in a hippocampal-dependent object location task and a prefron

193 lic pulse of estradiol prior to testing on a hippocampal-dependent object placement (OP) task to asse

194 Immediately after training in a hippocampal-dependent object recognition task, mice rece

195 sion levels of synaptic protein markers, and hippocampal-dependent object-placement memory as a behav

196 We developed a novel version of the hippocampal-dependent paired associate inference (PAI) p

197 In experiments using a hippocampal-dependent paired-associate task for rats, th

198 valuated brain activity at rest and during a hippocampal-dependent pattern separation task.

199 tly enhancing and attenuating, respectively, hippocampal-dependent place conditioning.

200 nvestigations to uncover the role of D2Rs in hippocampal-dependent plasticity and learning.

201 sNS selectively impaired working memory in a hippocampal-dependent radial arm water-maze task without

202 g performance of more cognitively demanding, hippocampal-dependent recognition memory tasks.

203 of the hippocampus, but left performance on hippocampal-dependent reference and working memory tasks

204 3 (n-3) fatty acids, and refined sugar, with hippocampal-dependent relational memory in prepubescent

205 t it is paradoxically less active during the hippocampal-dependent relational memory phase relative t

206 e was selectively positively associated with hippocampal-dependent relational memory.

207 In parallel, we show a shift away from hippocampal-dependent representational patterns to distr

208 gth, however, the functional neuroanatomy of hippocampal-dependent scene perception is unknown.

209 By 6 months, deficits in hippocampal-dependent spatial (Morris water maze) and as

210 c transmission, the mutants displayed normal hippocampal-dependent spatial and contextual memory but

211 treated with apamin demonstrated accelerated hippocampal-dependent spatial and nonspatial memory enco

212 hened short- and long-term memory in several hippocampal-dependent spatial and nonspatial tasks.

213 NAc shell DA as being necessary for enabling hippocampal-dependent spatial information to gain contro

214 nduced, and VGF mutant mice were impaired in hippocampal-dependent spatial learning and contextual fe

215 pheral metabolism and cognition, deficits in hippocampal-dependent spatial learning and memory were e

216 xpression may play a role in the deficits in hippocampal-dependent spatial learning and sleep/wake st

217 Hippocampal-dependent spatial learning tasks such as the

218 The status of hippocampal-dependent spatial learning was evaluated in

219 impaired acquisition, but not retrieval, of hippocampal-dependent spatial learning, a deficit that i

220 t impact anxiety/depression-like behavior or hippocampal-dependent spatial learning, it leads to an a

221 and aged rats behaviorally characterized in hippocampal-dependent spatial learning.

222 ective defects in LTP and in the encoding of hippocampal-dependent spatial memories.

223 kinase A, which has been reported to improve hippocampal-dependent spatial memory in aged animals, ha

224 contributing to the transformation of a new hippocampal-dependent spatial memory into a remote one a

225 Moreover, chronic restraint impaired hippocampal-dependent spatial memory on the Y maze (4-hr

226 ry using the T-maze, Y-maze, and water maze, hippocampal-dependent spatial memory tasks.

227 circuit is likely to mediate key aspects of hippocampal-dependent spatial memory.

228 Learning based on hippocampal-dependent spatial navigation in female rats

229 MK2/3 DKO mice have distinctive deficits in hippocampal-dependent spatial reversal learning.

230 levels were correlated with learning of the hippocampal-dependent spatial, but not hippocampal-indep

231 The threshold for hippocampal-dependent synaptic plasticity and memory sto

232 extends to the optimal phase for learning a hippocampal-dependent task and to the phase of hippocamp

233 t these effects extend to performance on the hippocampal-dependent task of trace conditioning.

234 ed aged rats behaviorally characterized in a hippocampal-dependent task to evaluate the status of lon

235 tion would affect trace fear conditioning, a hippocampal-dependent task.

236 been systematically evaluated on a specific hippocampal-dependent task.

237 py rescues the early cognitive deficits on a hippocampal-dependent task.

238 otor activity and decreased habituation in a hippocampal-dependent task.

239 of the literature in rodents has focused on hippocampal dependent tasks, studies suggest that tasks

240 lt neurogenesis supports performance in many hippocampal dependent tasks.

241 nd for behavioral phenotyping when nonvisual hippocampal-dependent tasks are utilized.

242 ayed by this important neuromodulator during hippocampal-dependent tasks in vivo.

243 se uptake observed during the performance of hippocampal-dependent tasks.

244 ology and function as well as performance on hippocampal-dependent tests of learning and memory in th

245 y generated neurons in the adult rat impairs hippocampal-dependent trace conditioning, a task in whic

246 g and memory function was assessed using the hippocampal-dependent trace eye-blink conditioning parad

247 in young and aged Long-Evans rats by using a hippocampal-dependent version of the Morris water maze.

248 ng communication partners, and the nature of hippocampal-dependent versus hippocampal-independent lea

249 separate explicit and implicit components of hippocampal-dependent visuomotor associative memories af

250 ack of contiguity renders trace conditioning hippocampal dependent, we designed a "contiguous trace c

251 ptic transmission and contextual learning is hippocampal dependent, we hypothesized that this deficit

252 lating neurogenesis caused an improvement of hippocampal-dependent working memory when repetitive inf