ライフサイエンスコーパス: histiocytic

1 ons in the tumor microenvironment, featuring histiocytic accumulation and widespread tumor necrosis.

2 Rare cases of histiocytic and dendritic cell (H/DC) neoplasms have bee

3 ry pigmented nodular adrenocortical disease, histiocytic and epithelial hyperplasias, lymphomas, and

4 c malignancies, including lymphoid, myeloid, histiocytic, and mast cell neoplasms.

5 oplasm and pleomorphic nuclei, and expressed histiocytic antigens in the absence of lymphocyte-specif

6 le xanthogranuloma (JXG) is a non-Langerhans histiocytic cell disorder in children which mostly affec

7 neonatal foreskin fibroblasts (HFF), and the histiocytic cell line U937 were cultured for designated

8 ed caspase-3 immunopositivity in lymphocytic/histiocytic cells.

9 ns of ECD seen on multimodal imaging include histiocytic choroidal infiltration causing choroidal les

10 10/21 [48%]), and lymphomas with a prominent histiocytic component (6/7 [86%]).

11 ibitor, vemurafenib, in 3 patients with rare histiocytic conditions, Erdheim-Chester disease and Lang

12 nsdifferentiation and acquired expression of histiocytic/dendritic cell markers.

13 morphologic and immunophenotypic evidence of histiocytic differentiation.

14 sed therapeutic strategies for patients with histiocytic diseases.

15 Erdheim-Chester disease (ECD) is a rare histiocytic disorder that is challenging to diagnose and

16 olecular pathology, and clinical features of histiocytic disorders have been identified.

17 ) and Erdheim-Chester disease (ECD) are rare histiocytic disorders induced by somatic mutation of MAP

18 The etiology of many histiocytic disorders is unknown, but our findings sugge

19 All of the lesions from histiocytic disorders were characterized by an extremely

20 nguishable between LCH and ECD, although the histiocytic disorders were distinct to HCL.

21 tment strategies for some of the most common histiocytic disorders, including Langerhans cell histioc

22 Lesions from other histiocytic disorders, juvenile xanthogranuloma, Erdheim

23 Lck-GM-CSF transgenic mice resemble those of histiocytic human diseases, such as Langerhans cell hist

24 terized by a predominantly polymorphonuclear/histiocytic infiltrate that contained lymphocytes and pl

25 Control mice exhibited mild lymphocytic and histiocytic infiltrates, whereas GKO mice developed larg

26 the lamina propria by lymphoplasmacytic and histiocytic infiltrates.

27 nosis of ECD in 1 case, with the presence of histiocytic infiltration, fibrosis, and characteristic i

28 eflected extracellular-matrix deposition and histiocytic infiltration.

29 Initial neutrophilic and histiocytic inflammation in affected tissues became prog

30 r lumina of the epididymides, and in foci of histiocytic inflammation in the brain, but not in organs

31 ogy comparable to that of WT mice, increased histiocytic inflammation was observed in the uterine hor

32 Lungs of control mice manifested exuberant histiocytic inflammation with visible C. neoformans, fin

33 eas of crypt hyperplasia and a predominantly histiocytic inflammatory cell infiltrate.

34 achio-cervical inflammatory myopathy (BCIM); histiocytic inflammatory myopathies, like sarcoid myopat

35 ed-Sternberg (H-RS) cells or lymphocytic and histiocytic (L&H) cells, respectively.

36 re is general agreement that lymphocytic and histiocytic (L&H) cells, the variants of Reed-Sternberg

37 od borne precursors lead to the formation of histiocytic lesions.

38 iated with Rhodococcus equi, including intra-histiocytic localization.

39 ) and chronic myelogenous (K-562) leukemias, histiocytic lymphoma (U-937), tongue (CAL 27) and pharyn

40 ibitor (Ki = 1 muM), decreases S1P levels in histiocytic lymphoma (U937) cells.

41 s transfected with full-length BAFF, or by a histiocytic lymphoma cell line (U937) that expresses BAF

42 The assay was evaluated with the histiocytic lymphoma cell line U937 and the topoisomeras

43 ol from primary human monocytes, human U-937 histiocytic lymphoma cells and from Chinese hamster ovar

44 ribed here found that adhesion of U937 human histiocytic lymphoma cells to FN provides a survival adv

45 Treatment of U937 human histiocytic lymphoma cells with E7389 led to time-depend

46 ) in IL-8 expression by "monocyte-like" U937 histiocytic lymphoma cells.

47 ct of LPS on TNF-mediated apoptosis in human histiocytic lymphoma U-937 cells was investigated.

48 4 on the cell surface TNF receptors in human histiocytic lymphoma U-937 cells.

49 We show that treatment of human histiocytic lymphoma U937 cells with the HIV-tat protein

50 ngth CD163 cDNAs from PAM, human U937 cells (histiocytic lymphoma), African green monkey kidney cells

51 ociated with rapid cell death in the diffuse histiocytic lymphoma, U937; Burkitt's lymphoma, ST486; b

52 True histiocytic lymphomas (THLs) are rare tumors in which th

53 otheliomas, osteosarcomas, sarcomas and true histiocytic lymphomas when injected in hamsters.

54 markers but showed a positive reactivity to histiocytic markers.

55 shes a novel, transplantable model of murine histiocytic/myeloid sarcoma that recapitulates the natur

56 angerhans cell histiocytosis (LCH) is a rare histiocytic neoplasm associated with somatic mutations i

57 erived xenotransplantation model for a human histiocytic neoplasm.

58 lassical hairy cell leukemia and a number of histiocytic neoplasms.

59 Mild-to-severe lymphoid depletion and histiocytic replacement were detected in lymphoid tissue

60 Moreover, murine histiocytic sarcoma could be similarly induced by intram

61 ce (mixed germ cell tumor, Triton tumor, and histiocytic sarcoma) also developed in Bax-/-ARF-/- anim

62 nts include primary myelofibrosis, leukemia, histiocytic sarcoma, and vasculitis.

63 i-Dorfman disease, juvenile xanthogranuloma, histiocytic sarcoma, xanthoma disseminatum, interdigitat

64 he systemic leukemic phenotypes exhibited by histiocytic sarcoma-bearing mice were nearly identical t

65 ing trans-differentiation into CD19-negative histiocytic sarcoma.

66 ematopoietic system in male and female mice (histiocytic sarcomas and malignant lymphomas), and ovary

67 tiple tumor phenotypes, including lymphomas, histiocytic sarcomas and, less frequently, mammary and h

68 The H/DC tumors included 7 histiocytic sarcomas, 5 of which showed evidence of dend

69 In this model, murine histiocytic sarcomas, equivalent to human myeloid sarcom

70 The histiocytic syndromes of childhood are disorders of the

71 ith evidence of nonlymphoid neoplasia of the histiocytic type leading to death within 4 weeks of age.