ライフサイエンスコーパス: histological

1 restored biochemical defects, corrected the histological abnormalities and improved the resistance t

2 that sustained COX-2/IKK2 expression caused histological abnormalities of pancreas, including increa

3 type and mdx mice, whereas the dko mice show histological abnormalities that are not observed in eith

4 do not cause haematological, biochemical or histological abnormalities, and are rapidly captured by

5 Adult DKO pancreata showed no histological abnormalities, and immunostaining of insuli

6 mproved diastolic dysfunction and attenuated histological abnormalities.

7 Histological activity appears to have an early threshold

8 and 1-mg TAC recipients compared with minor histological alterations in 3 and 5 mg TAC groups.

9 Coincident histological analyses confirmed the cellular basis of tr

10 mental conditions, and accorded closely with histological analyses in both relaxed and contracted sta

11 MSCs and BCs via activation of Fgf8 and Bmp4 Histological analyses indicated full regrowth of digit t

12 cle structural differences were confirmed by histological analyses of the gastrocnemius, revealing a

13 Virological and histological analyses revealed greater infection of musc

14 Unexpectedly, histological analyses revealed that the brain and liver

15 longitudinal magnetic resonance imaging and histological analyses to quantify changes in prostatic v

16 vWF, CD45, GFAP, and Iba-1) and motor neuron histological analyses were performed in cervical and lum

17 Detailed histological analyses were performed, and, when feasible

18 In conjunction with histological analyses, this approach has the high potent

19 ree of tissue inflammation was calculated by histological analyses.

20 00% long term survival, confirmed by MRI and histological analyses.

21 All tumours were harvested for histological analysis and comparison with elasticity mea

22 Clinical tissues are prepared for histological analysis and long-term storage via formalin

23 graft growth reached a plateau at 3 months, histological analysis confirmed progressive maturation f

24 Histological analysis confirmed specific uptake of (99m)

25 The immunological and histological analysis confirmed the positive radiologica

26 nfirmed the accuracy of the PET results, and histological analysis correlated high tumor uptake with

27 Histological analysis highlights myofibre formation, neo

28 Finally, histological analysis in human heart samples obtained fr

29 We also performed micro PET/CT and histological analysis of excised plaque.

30 Histological analysis of intestinal tissue revealed prof

31 Interestingly, histological analysis of lung lesions from Muc4(ko)/NDL

32 he bronchoalveolar lavage fluid, followed by histological analysis of lung sections.

33 Although histological analysis of lymphatic vessels in donor graf

34 Histological analysis of renal arteries yielded a mean n

35 e sacrificed for messenger RNA, protein, and histological analysis of the dorsal root ganglia, spinal

36 In this article we report a histological analysis of the FT NSC niche in postnatal r

37 Histological analysis of the lung sections from anti-IgE

38 Diagnosis was based on histological analysis of the tumour specimen after biops

39 lectrophysiological recordings in slices and histological analysis of the uptake of retrogradely tran

40 Histological analysis on tissue removed on day 14 post-o

41 Histological analysis revealed a significant correlation

42 Kidney histological analysis revealed no significant change in

43 Histological analysis revealed smaller adipocytes and qP

44 Histological analysis revealed structural and molecular

45 Histological analysis revealed that CAR-DCN treatment si

46 RNA sequencing and histological analysis revealed that MORs are expressed b

47 e wounds were ultimately healed in all mice, histological analysis revealed that, in non-transplanted

48 Histological analysis showed reduced collagen deposition

49 The histological analysis showed that remodeling and destruc

50 Histological analysis showed that the deletion of cycloo

51 nd urine sampling, and had kidneys taken for histological analysis.

52 10 young, 20 aged, and 18 with AD) underwent histological analysis.

53 hese data were combined with behavioural and histological analysis.

54 in vivo and investigate any correlation with histological analysis.

55 senilin-1 (PS1DeltaE9) was characterized for histological and behavioural signs of locus coeruleus dy

56 ed regularly, and tissues were collected for histological and biochemical analysis after 16 weeks of

57 M EDTA and may offer better preservation of histological and cellular structure.

58 se has been unequivocally shown to result in histological and clinical improvement.

59 tic increase in regeneration as evident from histological and electrophysiological analyses.

60 enes enriched in distinct cell types through histological and functional analyses, including rare sub

61 cal rejections has only proven beneficial to histological and functional outcome in studies in which

62 musculature and significant amelioration of histological and functional parameters.

63 ac surgeon intraoperatively and confirmed by histological and genetic examinations.

64 visual impairment at an early age, while the histological and immunofluorescence assays indicated the

65 A biopsy of the subcutaneous lesion showed histological and immunohistochemical characteristics of

66 Quantitative histological and in vivo MRI assessments of non-heme cel

67 -94 d of age and the liver was harvested for histological and metabolomic analyses.

68 X-ray, histological and micro CT (microCT) analyses showed that

69 On histological and micro PET/CT analysis, (18)F-fluoride s

70 l lesions from patients with metastatic PCa, histological and molecular analyses revealed that IL-1be

71 g in prostate tissue grafts with appropriate histological and molecular properties that respond to an

72 ive mice induces cutaneous inflammation with histological and molecular signs of both diseases.

73 pathogenesis of metaplastic carcinomas with histological and molecular similarities with human disea

74 Immunohistochemistry and histological and morphometric analyses revealed a twofol

75 ied by perturbations in metabolic, skeletal, histological and other physiological parameters.

76 ed staining of intact tissues with preserved histological and spatial information.

77 Histological and ultrastructural studies indicated that

78 rash, a monoclonal gammopathy, and clinical, histological, and biological signs of neutrophil-mediate

79 re collected on day 28 for further cellular, histological, and molecular analysis.

80 al cord injury using a combined behavioural, histological, and molecular approach.

81 ure-volume measurements, along with lung, RV histological, and protein analyses.

82 No endoscopic or histological anomalies were found at the anastomosis sit

83 res: Frequency, anatomic location, size, and histological appearance of connective tissue nevi in pat

84 PLC-derived organoid cultures preserve the histological architecture, gene expression and genomic l

85 Histological assessment indicated that deletion of TSP-1

86 Histological assessment of CA19-9 and CA-125 suggested t

87 l-characterized molecular markers, have made histological assessment of microglia populations more ac

88 A postmortem examination, including a histological assessment, revealed both BRSs to be patent

89 Following histological assessment, tumour-rich regions of formalin

90 d labeled these structures using an existing histological atlas.

91 pretype 2 diabetes, a result corroborated by histological beta-cell mass measurements and live-cell i

92 after adjusting for patient age, gender and histological brain tumor diagnosis (beta = -0.253, p < 0

93 We evaluated if histological categories at week 6 could predict the deve

94 lation and could alleviate CsA-induced renal histological changes and function.

95 We investigated histological changes and metabolomic profile in the live

96 this threshold correlates with metabolic and histological changes and whether a further accumulation

97 erone treatment, but not estradiol, produces histological changes in female rat liver that mimic NAFL

98 for macrophage phagocytosis activity, ocular histological changes, and retinal function.

99 A not only attenuated proteinuria and kidney histological changes, but also ameliorated podocyte and

100 and hormone receptor expression, but not the histological changes.

101 Most of the excised tissue samples displayed histological characteristics of bone, fibroproliferative

102 iple-negative (TN) breast cancer (BC) shares histological characteristics with germline BRCA1 mutatio

103 Histological chorioamnionitis (HCA) is an intrauterine i

104 accurately differentiate between 4 different histological classes.

105 ms (IPMNs) and predictors of their pathology/histological classification.

106 odel of HTG-AP that can mimic physiological, histological, clinical features of human HTG-AP and it c

107 refractory to the effects of anti-TNF: their histological colitis scores were as severe as those from

108 d colitis, disease activity index (DAI), and histological colitis scores, and increased the body weig

109 ndocardial contact electrogram amplitude and histological composition of myocardium.

110 ars, median 61.06 years) with 4 well defined histological conditions: 20 controls with histological f

111 at least 18 months post-treatment including histological confirmation of the occurrence of CIN2+.

112 This leads to a reciprocal pattern of histological correction in the respective tissues when c

113 f congenital diffuse lung disease, provide a histological correlate, and support a critical role for

114 In the absence of histological criteria that distinguish between inflammat

115 fication or documented mastocytosis based on histological criteria, at 50 centres in 15 countries.

116 neurobehavioral deficits, E/I imbalance, and histological damage are all ameliorated by treatment wit

117 There was no evidence of histological damage caused by Hemopure.

118 The incidence and severity of chronic histological damage have decreased substantially over th

119 vere and/or sustained, can result in chronic histological damage of which interstitial fibrosis and t

120 In addition, clinical symptoms and histological damage were more severe in AKAP12 KO mice t

121 The ensuing cellular infiltration, histological damage, and decline in lung function were q

122 ML) to classify disease using endoscopic and histological data for 287 children diagnosed with PIBD.

123 t lab migration experiments and quantitative histological data of human colorectal cancer tissue samp

124 Consideration of histological data reduced the number of kidneys thought

125 Histological data reveal that a large number of pretecta

126 oys mathematical modelling of endoscopic and histological data to aid diagnostic accuracy.

127 y, histological only and combined endoscopic/histological data yielding classification accuracy of 71

128 ix ontogenetic stages based on body size and histological data.

129 , gender, history of cardiovascular disease, histological diagnosis and adjuvant therapy.

130 The histological diagnosis at 6 weeks was: normal (n = 206),

131 surgical lung biopsy to secure a definitive histological diagnosis of usual interstitial pneumonia p

132 ngly, by postnatal day 60 it also caused CA1 histological disorganization, with a selective decline i

133 lastography and FibroTest were compared with histological endpoints.

134 orrelated with increased disease severity by histological evaluation and paw swelling compared with G

135 Histological evaluation demonstrated increased albumin i

136 Prostate cancer (PC) diagnosis is based on histological evaluation of prostate needle biopsies, whi

137 Prerecovery liver biopsy (PLB) allows histological evaluation of the organ before procurement.

138 aire and underwent endoscopic assessment and histological evaluation of their BE.

139 Histological evaluation showed larger lumen areas and ev

140 Histological evaluation was performed at 90 days.

141 detectable via dermatological inspection and histological evaluation.

142 ches confirm the need of both endoscopic and histological evidence for an accurate diagnosis.

143 Histological evidence from young rhesus monkeys suggests

144 and oligomeric amyloid beta (oAbeta) but no histological evidence of amyloid deposition.

145 with lower plasma histamine levels and with histological evidence of defective MC degranulation but

146 gressive form of invasive breast cancer with histological evidence of epithelial to mesenchymal trans

147 ormal perfusion by clinical imaging and lack histological evidence of hemorrhage organization or thro

148 Patients had histological evidence of metastatic or surgically unrese

149 Histological evidence of molting suggests that after sum

150 There was no histological evidence of rejection in the other 9 patien

151 Histological evidence of tubular injury and cell death w

152 Histological evidence suggests that neurons in the VNLL

153 nes in ex vivo fracture cultures, supporting histological evidence that transdifferentiation occurs a

154 The volumes of mPFC areas across histological, ex vivo and in vivo MRI delineations were

155 Histological examination demonstrated pathological findi

156 Histological examination included hematoxylin and eosin

157 Histological examination of allograft tissues showed a s

158 m both colonoscopy reports and corresponding histological examination of excised lesions.

159 Histological examination of hepatic and renal tissue fro

160 The histological examination of temporal bones of cadaver an

161 ere: 1) endoscopic findings of GU and biopsy histological examination plus rapid urease test indicati

162 Histological examinations of tissue sections confirm the

163 cy typical of classic HCM, and this prompted histological examinations.

164 Clinical and histological experimental autoimmune encephalomyelitis w

165 We reviewed histological features and clinical imaging properties, a

166 demonstrate that the tumorogenic potential, histological features and metastatic properties of PLC-d

167 the cranial nerves and meninges with typical histological features and molecular profiles of human rh

168 dalities as well as uncertainty about unique histological features and their predictive value.

169 Here, we demonstrate that these histological features are associated with distinct trans

170 lasma biomarkers to estimate the presence of histological features of AH among patients with clinical

171 test cohort, 46 of 83 (55%) patients showed histological features of AH.

172 The histological features of HCM include myocyte hypertrophy

173 The thyroid tumors closely phenocopied the histological features of human RAS-driven, poorly differ

174 cted by type 2 diabetes, and correlated with histological features of NASH; these observations provid

175 stage-specific and strongly associated with histological features of poor prognosis.

176 cle, we briefly introduce the anatomical and histological features of the human insula.

177 , oxygen extraction, metabolic activity, and histological features were compared during 6 hours of NM

178 Clinical and histological features, complement assessment, and free e

179 available clinical, laboratory, imaging, and histological features.

180 nohistochemistry and fluorescent staining of histological features.

181 ed histological conditions: 20 controls with histological finding of non-transformed gastric mucosa,

182 Histological findings and transcriptome changes indicate

183 Secondary outcomes suggest that histological findings do not directly contribute to majo

184 Histological findings were comparable between groups.

185 human coronary samples and corroborated with histological findings.

186 iarrhoea and is diagnosed by colonoscopy and histological findings.

187 l of 12 CpG sites within the L1 gene, to the histological grade of cervical precancer and cancer.

188 predictors in predicting histological type, histological grade, and FIGO stage were 0.993, 0.961 and

189 non-SMGs, which were highly associated with histological grade, histological type and FIGO stage, re

190 groups divided by the clinical endpoints of histological grade, histological type as well as the Int

191 stage III or IV) follicular lymphoma of WHO histological grades 1, 2, or 3a were randomly assigned (

192 f miR-218 were significantly associated with histological grades and lymph node metastasis.

193 towards the centre of the fibre was a novel histological hallmark in one family.

194 ed excellent agreement between the MALDI and histological images.

195 r blocking studies, western blot, and tissue histological imaging suggested that the observed BAT con

196 Use of the chick also allowed us to merge histological, immunochemical and cell proliferation labe

197 Histological, immunohistochemical, biochemical, function

198 (GPC3) has been reported to be an excellent histological immunomarker for HB.

199 ormation along with preservation of specific histological information at cellular levels.

200 f proteins directly on tissue samples, where histological information is preserved, remain challengin

201 eased serum alanine aminotransferase levels, histological injury, the number of terminal deoxynucleot

202 The histological integrity of the lungs is improved with iCR

203 ents (n = 324) were assessed by clinical and histological (Kleiner score) features.

204 d the different absorption sites assigned to histological landmarks for the three drugs.

205 ) polymorphism was demonstrated to influence histological liver damage in alcoholic liver disease, no

206 This Review describes the clinical and histological manifestations of AMR, and discusses the im

207 ed ligand binding in post-mortem tissue, and histological markers of dopaminergic integrity.

208 is, as assessed by measuring biochemical and histological markers.

209 regation was also apparent by an increase in histological measures of tau pathology in young APP/PS1-

210 crab Neohelice granulata using a variety of histological methods that include silver reduced stainin

211 Here, using a palette of histological methods we describe neurons and their neuro

212 ded in paraffin, sectioned, and analyzed via histological methods.

213 ung cancer (NSCLC) and are distinct in their histological, molecular and clinical presentation.

214 ighlights the need for combined quantitative histological MRI studies.SIGNIFICANCE STATEMENT This stu

215 Close agreement between histological myelin staining and MPF suggests that fast

216 epatic inflammation was further confirmed by histological observation of increase of infiltrated neut

217 re developed utilising endoscopic data only, histological only and combined endoscopic/histological d

218 We found no histological or behavioral differences between adult wil

219 ce, incidence, progression, or regression of histological or cytological cervical abnormalities, or i

220 (-1)) was infused, and the heart removed for histological or electrophysiological study.

221 e, demonstrating the need to investigate the histological origin of gray matter alterations for every

222 By providing information on the histological origins of cerebral gray matter alterations

223 ALCL, we treated ALK- cell lines of various histological origins with JAK inhibitors.

224 nd after a further 6 months of follow-up for histological outcomes (dataset closed 31 August 2016).

225 0) serum keratin-18 fragments (n = 204) with histological parameters (n = 106) in heavy drinkers prim

226 Among the histological parameters, both M30/65 correlated signific

227 essing a range of metabolic, biochemical and histological parameters.

228 sse and sagA deletion-caused changes in the histological pattern at skin infection sites could be co

229 response after infection with L. interrogans Histological periodic acid-Schiff D staining of infected

230 s a distinctive serum biochemical as well as histological phenotype.

231 we aimed to identify these mPFC subareas in histological preparations of human brain tissue, determi

232 co-primary endpoints were treatment failure (histological progression of cancer from low to moderate

233 om healthy controls in parallel with classic histological quantification of beta-cell mass from pancr

234 Histological regression of BE was seen in 41% (20/49).

235 presenting with residual masses on MRI had a histological response >50%.

236 Histological review was performed on liver core biopsies

237 Histological sample preparation procedures are generally

238 tent than that with MSC in reducing DAI, the histological score, and nitrite levels.

239 ntestinal barrier disruption, with increased histological scores and proinflammatory cytokine express

240 allocated according to reliable clinical or histological scores, dual and single ECD transplantation

241 applicability and prognostic value of three histological scoring systems in a single PSC cohort.

242 nella species using cleared whole-mounts and histological sectioning combined with three-dimensional

243 Using classical histological sectioning in combination with fluorescent

244 ated by a network of channels that appear in histological sections as interstitial gaps.

245 on data collected in two dimensions: either histological sections imaged by light microscopy, or ele

246 mposition of calcifications contained within histological sections of breast tissue biopsies, and rel

247 Histological sections of treated tumors have detected re

248 mice were initially evaluated by PPCST with histological sections subsequently analyzed to confirm t

249 Microglia morphology was quantified from histological sections using Image J skeleton and fractal

250 Lung injury scoring of histological sections was significantly worse in mitocho

251 Histological sections were used for the morphometric ana

252 Histological severity of liver disease (inflammation, ba

253 rvations were mirrored in transcriptomic and histological signatures of residual cancer cells from ne

254 -term allograft survival (>100 days) without histological signs of chronic rejection, whereas the sim

255 blast development, confirmed by Micro-CT and histological staining as well as expression of osteoblas

256 Consecutive histological staining demonstrated that the signaling co

257 Moreover, histological staining exhibited goblet cell hyperplasia,

258 microscopy in neutrophils and macrophages by histological staining.

259 k of therapeutic failure associated with the histological status of the margins of the tissue excised

260 tioxidant defense system and preservation of histological structure and electrophysiological function

261 Histological structure of the retina was examined using

262 ally, ex vivo biodistribution, blocking, and histological studies were performed to establish the aff

263 d symptom-free survival, bacteriological and histological studies, as well as flow cytometry and meas

264 ss on the infarcted heart were studied using histological studies, assessment of protein, and gene ex

265 The liver function test and histological study revealed minimal hepatocyte, biliary

266 In this MRI-histological study, postmortem in situ scans were acquir

267 Histological subgroups included: early lesions (n = 1);

268 The main histological subtype in our cohort and combined analyses

269 signet-ring cell carcinoma (SRCC) is a rare histological subtype of colorectal adenocarcinoma, which

270 this work was to document the prevalence and histological subtype of lesions seen in patients aged <5

271 tified by age (</=18 years vs >18 years) and histological subtype.

272 tric rhabdomyosarcoma (RMS), irrespective of histological subtype.

273 them as biomarkers for the classification of histological subtypes and the prediction of clinical out

274 geneity in genetic susceptibility across the histological subtypes of lung cancer, with four loci ass

275 er cells and soft tissue sarcomas of diverse histological subtypes.

276 ood and adult tumours encompassing all major histological subtypes.

277 The histological sum score was 2.9 +/- 1.4 in the BAV group

278 electromyography, behavioral follow-up, and histological techniques was used to characterize spastic

279 g of the notochord has classically relied on histological techniques, which introduces sectioning art

280 rescence workflow on FFPE sections milled at histological thickness, cellular architecture can now be

281 have limitations in preserving molecular and histological tissue morphology, resulting in interfered

282 PET) probe for imaging DIPG in vivo In human histological tissues, the probes target, PARP1, was high

283 Here, we exploit histological, transcriptomic, and tomographic methods to

284 l cancer patients, with subgroup analyses by histological type (squamous cell carcinoma vs adenocarci

285 e highly associated with histological grade, histological type and FIGO stage, respectively, from the

286 nd most common differentiated thyroid cancer histological type and has been overshadowed by its more

287 he clinical endpoints of histological grade, histological type as well as the International Federatio

288 sophageal squamous cell carcinoma is a major histological type of esophageal cancer, with distinct in

289 elated with T stage, N stage, TNM stage, and histological type of the disease.

290 e, we assessed such disparities according to histological type, based on a variety of disparity metri

291 ntified non-SMGs as predictors in predicting histological type, histological grade, and FIGO stage we

292 this study, we show for the first time that histological types of breast tumors can be classified us

293 system, we succeeded in classifying the four histological types with 90.9% accuracy.

294 When stratified by different histological types, low FSTL1, BMP4, and Smad4 expressio

295 ively, and this difference remained for both histological types.

296 titatively measured 11661 nuclei on the four histological types: normal cases, usual ductal hyperplas

297 ence of PFC-labeled CAR T cells, followed by histological validation.

298 Group (COG; ANBL1221), patients had to have histological verification of neuroblastoma or ganglioneu

299 rcinoma based on noninvasive methods without histological verification, possibly associated with miss

300 identified in MRI and normalized to chronic histological volume.